Compounds > chloroquine

chloroquine and trametinib

chloroquine has been researched along with trametinib in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Affolter, KE; Boespflug, AM; Burrell, LD; Camolotto, SA; Cavalieri, CC; Cutler, SL; Foth, M; Gilcrease, GW; Guillen, KP; Kinsey, CG; Lum, DH; McMahon, M; Rehbein, KM; Scaife, CL; Schuman, SS; Seipp, MT; Shea, JE; Snyder, EL; Truong, A; Welm, AL; Welm, BE; Whisenant, JR; Yap, JT1
Evernden, BR; Forsyth, P; Fusco, MJ; Macaulay, RJ; Peguero, E; Piña, Y; Smalley, KS; Walko, CM1
Blumer, KJ; Dale, KJ; Ghazi, PC; Kinsey, CG; McMahon, M; Odelberg, SJ; Onken, MD; Richards, JR; Sanchez, JMS; Scherzer, MT; Shin, D; Truong, A; Yoo, JH1
Affolter, K; Gudipaty, S; Kinsey, C; McMahon, M; Rohweder, R; Schuman, S; Silva, D; Silvis, MR; Truong, A; Yap, J1

Other Studies

4 other study(ies) available for chloroquine and trametinib

ArticleYear
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.
    Nature medicine, 2019, Volume: 25, Issue:4

    Topics: Animals; Autophagy; CA-19-9 Antigen; Cell Line, Tumor; Chloroquine; Humans; MAP Kinase Signaling System; Mice, SCID; Mitogen-Activated Protein Kinase Kinases; Pancreatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; ras Proteins; Xenograft Model Antitumor Assays

2019
Using personalized medicine in gliomas: a genomic approach to diagnosis and overcoming treatment resistance in a case with pleomorphic xanthoastrocytoma.
    Journal of neurology, 2020, Volume: 267, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chloroquine; Drug Resistance, Neoplasm; Humans; Imidazoles; Male; Oximes; Precision Medicine; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Young Adult

2020
Chloroquine Sensitizes
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 12-01, Volume: 26, Issue:23

    Topics: Animals; Antimalarials; Apoptosis; Cell Proliferation; Chloroquine; Drug Resistance, Neoplasm; Drug Therapy, Combination; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Mutation; Protein Kinase Inhibitors; Pyridones; Pyrimidinones; Tumor Cells, Cultured; Uveal Neoplasms; Xenograft Model Antitumor Assays

2020
MYC-mediated resistance to trametinib and HCQ in PDAC is overcome by CDK4/6 and lysosomal inhibition.
    The Journal of experimental medicine, 2023, 03-06, Volume: 220, Issue:3

    Topics: Carcinoma, Pancreatic Ductal; Chloroquine; Cyclin-Dependent Kinase 4; Humans; Hydroxychloroquine; Lysosomes; Pancreatic Neoplasms

2023