chloroquine and tilorone

chloroquine has been researched along with tilorone in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's3 (21.43)18.2507
2000's1 (7.14)29.6817
2010's4 (28.57)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Denny, WA; Feigon, J; Kearns, DR; Leupin, W1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Byun, SY; Choi, I; Jeon, S; Kim, S; Ko, M; Lee, J; Park, S; Shum, D1
Anderson, SN; Kacew, S; Ruben, Z1
Shall, S; Tavassoli, M; Tavassoli, MH1
DiPasquale, G; Hubbs, SJ; Marks, RL; Pasternak, RD1
D'Amico, DJ; Kenyon, KR1
Lüllmann-Rauch, R; Pods, R; Von Witzendorff, B2
Bodem, J; Diesendorf, V; Fähr, S; Geiger, N; Obernolte, H; Roll, V; Sewald, K1

Other Studies

14 other study(ies) available for chloroquine and tilorone

ArticleYear
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship

1984
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs.
    Antimicrobial agents and chemotherapy, 2020, 06-23, Volume: 64, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Betacoronavirus; Cell Line; Chlorocebus aethiops; Coronavirus Infections; COVID-19; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Niclosamide; Pandemics; Pneumonia, Viral; Pregnenediones; SARS-CoV-2; Vero Cells

2020
Changes in saccharide and phospholipid content associated with drug storage in cultured rabbit aorta muscle cells.
    Laboratory investigation; a journal of technical methods and pathology, 1991, Volume: 64, Issue:4

    Topics: Amines; Amiodarone; Animals; Anti-Arrhythmia Agents; Aorta; Cells, Cultured; Chloroquine; Desipramine; Ethylenediamines; Kinetics; Microscopy, Electron; Monosaccharides; Muscle, Smooth, Vascular; Phospholipids; Piperidines; Rabbits; Tilorone

1991
Effect of DNA intercalators on poly(ADP-ribose) glycohydrolase activity.
    Biochimica et biophysica acta, 1985, Mar-01, Volume: 827, Issue:3

    Topics: Aminoacridines; Amsacrine; Animals; Chloroquine; Daunorubicin; DNA; Ellipticines; Ethacridine; Ethidium; Glycoside Hydrolases; Histones; Intercalating Agents; Kinetics; Proflavine; Swine; Thymus Gland; Tilorone

1985
Effect of antirheumatic agents on the mitogen response of arthritic rat spleen cells.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Arthritis, Rheumatoid; Chloroquine; Gold Sodium Thiomalate; Levamisole; Lymphocyte Activation; Male; Penicillamine; Rats; Rats, Inbred Lew; Spleen; Tilorone

1985
Drug-induced lipidoses of the cornea and conjunctiva.
    International ophthalmology, 1981, Volume: 4, Issue:1-2

    Topics: Amiodarone; Amodiaquine; Chloroquine; Conjunctival Diseases; Corneal Diseases; Fabry Disease; Female; Gentamicins; Humans; Hydroquinones; Lipidoses; Male; Tilorone

1981
Tilorone-induced lysosomal storage of sulphated glycosaminoglycans can be separated from tilorone-induced enhancement of lysosomal enzyme secretion.
    Biochemical pharmacology, 1995, May-11, Volume: 49, Issue:9

    Topics: Ammonium Chloride; Animals; beta-N-Acetylhexosaminidases; Cattle; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Fibroblasts; Glycosaminoglycans; Lysosomes; Mucopolysaccharidoses; Tilorone

1995
The antimalarials quinacrine and chloroquine induce weak lysosomal storage of sulphated glycosaminoglycans in cell culture and in vivo.
    Toxicology, 1996, Jun-17, Volume: 110, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Antimalarials; beta-N-Acetylhexosaminidases; Cattle; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Female; Fibroblasts; Glycosaminoglycans; Histocytochemistry; Lipidoses; Liver; Lysosomes; Microscopy, Electron; Microscopy, Fluorescence; Mucopolysaccharidoses; Quinacrine; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfates; Tilorone

1996
Drug-induced phospholipidosis is not correlated with the inhibition of SARS-CoV-2 - inhibition of SARS-CoV-2 is cell line-specific.
    Frontiers in cellular and infection microbiology, 2023, Volume: 13

    Topics: Antiviral Agents; Cell Line; Chloroquine; COVID-19; Fluoxetine; Humans; SARS-CoV-2; Tilorone

2023