chloroquine and thioridazine

chloroquine has been researched along with thioridazine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19908 (33.33)18.7374
1990's1 (4.17)18.2507
2000's7 (29.17)29.6817
2010's6 (25.00)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Sen, S; Sinha, N1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Byun, SY; Choi, I; Jeon, S; Kim, S; Ko, M; Lee, J; Park, S; Shum, D1
Gershon, S; Hine, B; Sakalis, G; Traficante, LJ1
Greenseid, DZ; Zinn, KM1
Hayasaka, S; Mizuno, K; Tsuchiya, M1
Onaya, T1
Davidorf, FH1
Podos, SM1
Grützner, P1
Potts, AM1
Balafa, C; Eves, P; Hedley, S; Mac Neil, S; Smith-Thomas, L; Wagner, M1
Toler, SM1
Steffen, AC; Sundberg, AL1
Duarte, D; Nunes, M; Ricardo, S; Vale, N1

Reviews

4 review(s) available for chloroquine and thioridazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Toxicology of the retinal pigment epithelium.
    International ophthalmology clinics, 1975,Spring, Volume: 15, Issue:1

    Topics: Animals; Chloroquine; Chlorpromazine; Dose-Response Relationship, Drug; Epithelium; Humans; Melanins; Retinal Diseases; Thioridazine

1975
[Thyroid stimulating hormone (TSH)].
    Horumon to rinsho. Clinical endocrinology, 1971, Volume: 19, Issue:10

    Topics: Adenylyl Cyclases; Animals; Chloroquine; Chlorpheniramine; Cyclic AMP; Dactinomycin; Iodine; Lysosomes; Phlorhizin; Phospholipids; Prostaglandins; Protein Biosynthesis; Rats; Thioridazine; Thyroid Gland; Thyrotropin; Trifluoperazine

1971
Oxidative stress plays an important role in the pathogenesis of drug-induced retinopathy.
    Experimental biology and medicine (Maywood, N.J.), 2004, Volume: 229, Issue:7

    Topics: Animals; Blindness; Chloroquine; Humans; Indomethacin; Oxidative Stress; Retina; Retinal Diseases; Tamoxifen; Thioridazine

2004

Trials

1 trial(s) available for chloroquine and thioridazine

ArticleYear
Chloroquine potentiation of thioridazine effects in rats and drug-resistant schizophrenic patients: a preliminary report.
    Communications in psychopharmacology, 1977, Volume: 1, Issue:4

    Topics: Amphetamine; Animals; Brain; Chloroquine; Clinical Trials as Topic; Drug Resistance; Drug Synergism; Humans; Male; Rats; Schizophrenia; Stereotyped Behavior; Thioridazine; Time Factors

1977

Other Studies

19 other study(ies) available for chloroquine and thioridazine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs.
    Antimicrobial agents and chemotherapy, 2020, 06-23, Volume: 64, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Betacoronavirus; Cell Line; Chlorocebus aethiops; Coronavirus Infections; COVID-19; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Niclosamide; Pandemics; Pneumonia, Viral; Pregnenediones; SARS-CoV-2; Vero Cells

2020
Affinity of ocular acid-insoluble melanin for drugs in vitro.
    Investigative ophthalmology & visual science, 1987, Volume: 28, Issue:5

    Topics: Animals; Cattle; Chloroquine; Ciliary Body; Daunorubicin; Eye; Hydrogen-Ion Concentration; Iris; Melanins; Pharmaceutical Preparations; Spectrophotometry; Thioridazine

1987
Ocular toxicity of systemic drugs. A review of the effects of seven commonly used agents.
    The Ohio State medical journal, 1972, Volume: 68, Issue:11

    Topics: Chloramphenicol; Chloroquine; Chlorpromazine; Contraceptives, Oral; Eye Diseases; Glucocorticoids; Humans; Indomethacin; Thioridazine

1972
Retinal pigmentary disease.
    International ophthalmology clinics, 1967,Winter, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Blindness; Brain Diseases; Chloroquine; Chorioretinitis; Choroid; Diagnosis, Differential; Eye Diseases; Female; Friedreich Ataxia; Fundus Oculi; Humans; Lipidoses; Male; Night Blindness; Ophthalmoscopy; Pigmentation Disorders; Retinal Pigments; Retinitis; Retinitis Pigmentosa; Rubella; Scotoma; Syphilis, Congenital; Thioridazine

1967
Acquired color vision defects secondary to retinal drug toxicity.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1969, Volume: 158 Suppl

    Topics: Adult; Chloroquine; Color Perception Tests; Color Vision Defects; Digoxin; Eye Diseases; Female; Humans; Indomethacin; Male; Middle Aged; Retina; Thioridazine

1969
Agents which cause pigmentary retinopathy.
    Diseases of the nervous system, 1968, Volume: 29, Issue:3

    Topics: Antibiotics, Antineoplastic; Chloroquine; Chlorpromazine; Chronic Disease; Female; Humans; Iodine; Male; Retinitis Pigmentosa; Salts; Thioridazine; Time Factors

1968
A comparative study of the effect of pigment on drug toxicity in human choroidal melanocytes and retinal pigment epithelial cells.
    Pigment cell research, 1999, Volume: 12, Issue:1

    Topics: Antimalarials; Antipsychotic Agents; Cell Survival; Chloroquine; Choroid; Estrogen Antagonists; Flow Cytometry; Humans; Melanins; Melanocytes; Monophenol Monooxygenase; Phagocytosis; Pigment Epithelium of Eye; Pigmentation; Pigments, Biological; Retina; Tamoxifen; Thioridazine; Ultraviolet Rays; Xenobiotics

1999
Enhancing the effect of radionuclide tumor targeting, using lysosomotropic weak bases.
    International journal of radiation oncology, biology, physics, 2007, Jan-01, Volume: 67, Issue:1

    Topics: Amantadine; Ammonium Chloride; Antimalarials; Antipsychotic Agents; Antiviral Agents; Astatine; Carcinoma, Squamous Cell; Cell Line, Tumor; Chloroquine; Epidermal Growth Factor; Glioma; Humans; Iodine Radioisotopes; Radioimmunotherapy; Radioisotopes; Recombinant Fusion Proteins; Thioridazine

2007
Combination of Antimalarial and CNS Drugs with Antineoplastic Agents in MCF-7 Breast and HT-29 Colon Cancer Cells: Biosafety Evaluation and Mechanism of Action.
    Biomolecules, 2022, Oct-16, Volume: 12, Issue:10

    Topics: Adenosine Diphosphate; Antimalarials; Antineoplastic Agents; Artesunate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benztropine; Breast Neoplasms; Cell Line, Tumor; Chloroquine; Colonic Neoplasms; Containment of Biohazards; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Fluoxetine; Fluphenazine; Humans; Ki-67 Antigen; MCF-7 Cells; Michigan; NF-kappa B; Paclitaxel; Poly(ADP-ribose) Polymerase Inhibitors; Ribose; Sertraline; Thioridazine

2022