chloroquine has been researched along with theophylline in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (44.83) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 6 (20.69) | 29.6817 |
| 2010's | 9 (31.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bathurst, I; Burrows, JN; Charman, SA; Cross, RM; Flanigan, DL; Fronczek, FR; Guida, WC; Kyle, DE; LaCrue, AN; Maignan, JR; Manetsch, R; Monastyrskyi, A; Mutka, TS; Sáenz, FE; Shackleford, DM; White, KL; Wojtas, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Scott, WA; Solomon, B | 1 |
| Latarjet, R; Zajdela, F | 1 |
| Gombe, S; Norman, C | 1 |
| Thurn, G | 1 |
| Alberto, R; Lyman, M; May, CD | 1 |
| Dukor, P; Weissmann, G; Zurier, RB | 1 |
| Dinnendahl, V; Peters, HD; Schönhöfer, PS | 1 |
| Fain, JN; Pointer, RH | 1 |
| Hawkins, D | 1 |
| Furkert, K | 1 |
| Igarashi, SJ; Nakano, NI | 1 |
| Adewunmi, AI; Enwonwu, CO; Okolie, EE | 1 |
| Donowitz, M; Fogel, R; Sharp, GW | 1 |
| Ashton, M; Motti, BA | 1 |
| Insanov, AB; Mustafaeva, LI | 1 |
2 review(s) available for chloroquine and theophylline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Antiasthmatics. 12].
Topics: Adrenal Cortex Hormones; Aminophylline; Anti-Bacterial Agents; Asthma; Atropine; Barbiturates; Bronchodilator Agents; Calcium Chloride; Central Nervous System Stimulants; Chloroquine; Ephedrine; Epinephrine; Expectorants; Histamine H1 Antagonists; Humans; Isoproterenol; Papaverine; Phenothiazines; Potassium Iodide; Theophylline; Trypsin | 1967 |
27 other study(ies) available for chloroquine and theophylline
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.
Topics: Animals; Antimalarials; Humans; Inhibitory Concentration 50; Malaria; Mice; Microsomes, Liver; Parasitemia; Plasmodium; Plasmodium berghei; Quinolones; Structure-Activity Relationship | 2014 |
Adenosine 3',5'-cyclic monophosphate and morphology in Neurospora crassa: drug-induced alterations.
Topics: Adenylyl Cyclases; Antimalarials; Atropine; Chloroquine; Cyclic AMP; Histamine; Kinetics; Neurospora; Neurospora crassa; Phosphoric Diester Hydrolases; Quinidine; Quinine; Theophylline | 1975 |
Inhibition of skin carcinogenesis in vivo by caffeine and other agents.
Topics: Animals; Caffeine; Cell Line; Chloroquine; DNA; DNA Repair; Female; Malondialdehyde; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Skin; Skin Neoplasms; Theophylline; Ultraviolet Rays | 1978 |
Stimulatory effect of the lysosomal stabilizer, chloroquine, on the respiration and motility of fresh and aged bovine spermatozoa.
Topics: Animals; Caffeine; Cattle; Chloroquine; In Vitro Techniques; Male; Oxygen Consumption; Sperm Motility; Sperm Tail; Spermatozoa; Stimulation, Chemical; Theophylline; Tissue Preservation | 1975 |
[Side effects of various drugs acting on the eye].
Topics: Cardiac Glycosides; Chloroquine; Contraceptives, Oral; Cyproheptadine; Drug-Related Side Effects and Adverse Reactions; Eye Diseases; Female; Ganglionic Blockers; Glaucoma; Humans; Insulin; Intraocular Pressure; Male; Methyldopa; Muscle Relaxants, Central; Parasympatholytics; Reserpine; Sympathomimetics; Theophylline | 1972 |
Effects of compounds which inhibit lymphocyte stimulation on the utilization of glucose by leukocytes.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Carbon Isotopes; Chloroquine; Colchicine; Culture Media; Culture Techniques; Ethanol; Glucose; Humans; Hydrocortisone; Lectins; Leukocytes; Lymphocyte Activation; Lymphocytes; Niacinamide; Ouabain; Theophylline; Time Factors; Tritium | 1970 |
Effect of cyclic AMP on release of lysosomal enzymes from phagocytes.
Topics: Adenine Nucleotides; Amidohydrolases; Animals; Cathepsins; Chloroquine; Colchicine; Culture Techniques; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dimethyl Sulfoxide; Glucuronidase; Humans; Hydrolases; L-Lactate Dehydrogenase; Leukocytes; Lysosomes; Macrophages; Mice; Phagocytosis; Prostaglandins; Stimulation, Chemical; Sulfatases; Theophylline; Vinblastine; Zymosan | 1971 |
Effects of antilipolytic drugs on cyclic 3',5'-AMP dependent protein kinase.
Topics: Adipose Tissue; Animals; Cattle; Chloroquine; Cyclic AMP; Dose-Response Relationship, Drug; Flufenamic Acid; In Vitro Techniques; Insulin; Lipid Metabolism; Mefenamic Acid; Muscles; Nicotinic Acids; Norepinephrine; Phentolamine; Phenylbutazone; Phosphotransferases; Propranolol; Prostaglandins; Protein Kinase Inhibitors; Protein Kinases; Pyrazoles; Theophylline | 1973 |
Response of isolated white fat cells to anti-malarial drugs.
Topics: Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Antimalarials; Bucladesine; Chloroquine; Drug Synergism; Fatty Acids, Nonesterified; Female; Glycerol; Norepinephrine; Primaquine; Proteins; Quinacrine; Quinidine; Rats; Theophylline; Triglycerides | 1973 |
Neutrophilic leukocytes in immunologic reactions in vitro. 3. Pharmacologic modulation of lysosomal constituent release.
Topics: Animals; Bucladesine; Chloroquine; Colchicine; Collagen; Epinephrine; Ethylmaleimide; Exocytosis; Ferritins; Glucose; Hydrocortisone; Iodoacetates; Isoproterenol; Latex; Lysosomes; Membranes; Microspheres; Models, Biological; Neutrophils; Phagocytosis; Phenylephrine; Propranolol; Rabbits; Salicylates; Theophylline; Vinblastine | 1974 |
Molecular interactions of pyrimidines, purines, and some other heteroaromatic compounds in aqueous media.
Topics: Adenine; Caffeine; Chemical Phenomena; Chemistry; Chloroquine; Drug Stability; Guanidines; Hypoxanthines; Nucleosides; Purines; Pyrimidines; Quinoxalines; Solubility; Theophylline; Tritium; Water | 1970 |
Antimalarial activity of inhibitors of ADP-ribosyl transferase against Plasmodium yoelii infection in mice. 1. Preliminary data.
Topics: Animals; Antimalarials; Benzamides; Chloroquine; Drug Evaluation, Preclinical; Malaria; Male; Mice; Niacinamide; Nucleotidyltransferases; Plasmodium; Poly(ADP-ribose) Polymerases; Theobromine; Theophylline | 1982 |
Chloroquine stimulates absorption and inhibits secretion of ileal water and electrolytes.
Topics: Absorption; Animals; Calcium; Chloroquine; Cholera Toxin; Cyclic AMP; Electrolytes; Ileum; Male; Rabbits; Rats; Rats, Inbred Strains; Stimulation, Chemical; Theophylline; Water | 1982 |
No effect of chloroquine on theophylline pharmacokinetics in the rat.
Topics: Animals; Antimalarials; Chloroquine; Data Interpretation, Statistical; Drug Interactions; Male; Rats; Rats, Sprague-Dawley; Theophylline; Time Factors; Vasodilator Agents | 1998 |
[Insanovin aerosol therapy in the treatment of bronchial asthma].
Topics: Adult; Aerosols; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchodilator Agents; Chloroquine; Drug Combinations; Ephedrine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prednisolone; Respiratory Function Tests; Theophylline; Time Factors | 2004 |