chloroquine and tamoxifen

chloroquine has been researched along with tamoxifen in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.13)18.7374
1990's4 (8.51)18.2507
2000's17 (36.17)29.6817
2010's22 (46.81)24.3611
2020's3 (6.38)2.80

Authors

AuthorsStudies
Gochfeld, DJ; Hamann, MT1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Alvarez, DE; Boiani, L; Bollini, M; Bruno, AM; Casal, JJ; Cerecetto, H; González, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
De Vita, D; Di Santo, R; Maes, L; Matheeussen, A; Moraca, F; Pandolfi, F; Scipione, L; Tortorella, S; Zamperini, C1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Augustyns, K; Baán, A; Caljon, G; Kiekens, F; Maes, L; Matheeussen, A; Salado, IG; Van der Veken, P; Verdeyen, T1
Amporndanai, K; Antonyuk, S; Berry, NG; Biagini, GA; David Hong, W; Davies, J; Leung, SC; Nixon, GL; O'Neill, PM; Priestley, RS; Samar Hasnain, S; Ward, SA1
Caljon, G; Courtens, C; Maes, L; Martin, A; Risseeuw, M; Van Calenbergh, S1
Caljon, G; Cos, P; Courtens, C; Martin, A; Risseeuw, M; Van Calenbergh, S1
Caljon, G; Cos, P; Courtens, C; Maes, L; Martin, A; Risseeuw, M; Van Calenbergh, S1
Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL1
Balde, AM; Baldé, MA; Caljon, G; Cos, P; Foubert, K; Herrebout, W; Matheeussen, A; Peeters, L; Pieters, L; Traoré, MS; Tuenter, E; Vermeyen, T1
Drenckhahn, D; Jacobi, B; Lüllmann-Rauch, R1
Kayyali, R; Marriott, C; Wiseman, H1
Salminen, L; Tähti, H; Toimela, T2
Balafa, C; Eves, P; Hedley, S; Mac Neil, S; Smith-Thomas, L; Wagner, M1
Mäenpää, H; Mannerström, M; Salminen, L; Tähti, H; Toimela, T1
Diehl, H; Engelke, M; Huhtala, A; Mäenpää, H; Mannerström, M; Mäntylä, E; Mäntylä, M; Marselos, M; Pappas, P; Salminen, L; Tähti, H; Toimela, T; Uusitalo, H; Zorn-Kruppa, M1
Mäenpää, H; Mannerström, M; Salminen, L; Saransaari, P; Tähti, H; Toimela, T1
Mäenpää, H; Mannerström, M; Saransaari, P; Tähti, H; Toimela, T1
Toler, SM1
Beraru, V1
Amaravadi, RK; Bui, T; Christophorou, MA; Evan, GI; Lum, JJ; Thomas-Tikhonenko, A; Thompson, CB; Yu, D1
Ravet, O1
Laties, AM; Liu, J; Lu, W; Mitchell, CH; Nguyen, J; Reigada, D1
Garralda Luquin, A1
Aréchiga-Figueroa, IA; Ferrer, T; López-Izquierdo, A; Ponce-Balbuena, D; Rodríguez-Menchaca, AA; Sánchez-Chapula, JA1
Hoffmann, GR; Laterza, AM; Sylvia, KE; Tartaglione, JP1
Flomenberg, N; Howell, A; Ko, YH; Lin, Z; Lisanti, MP; Martinez-Outschoorn, UE; Pestell, RG; Sotgia, F1
Ann, DK; Chen, YR; Hu, S; Liu, X; Ma, H; Tsou, B; Yen, Y1
Abdulaziz, N; McCune, WJ; Shah, AR1
Beljanski, V; Nathanson, L; Noren, H; Rossi, F; Sarria, L; Schiller, PC1
Banga, R; Banga, V; Beljanski, V; Eltalla, A; Iyer, E; Kumrah, N; Naim, M; Nathanson, L; Parag, S; Shahin, L; Zacharias, B1

Reviews

7 review(s) available for chloroquine and tamoxifen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
    Medicinal research reviews, 2021, Volume: 41, Issue:1

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization

2021
Oxidative stress plays an important role in the pathogenesis of drug-induced retinopathy.
    Experimental biology and medicine (Maywood, N.J.), 2004, Volume: 229, Issue:7

    Topics: Animals; Blindness; Chloroquine; Humans; Indomethacin; Oxidative Stress; Retina; Retinal Diseases; Tamoxifen; Thioridazine

2004
[Drug-induced retinopathies].
    Oftalmologia (Bucharest, Romania : 1990), 2006, Volume: 50, Issue:3

    Topics: Chloroquine; Humans; Phenothiazines; Piperazines; Purines; Retinal Diseases; Sildenafil Citrate; Sulfones; Tamoxifen; Vasodilator Agents

2006
[Toxic effects of medications on the cornea].
    Bulletin de la Societe belge d'ophtalmologie, 2007, Issue:304

    Topics: Belgium; Chloroquine; Cornea; Corneal Diseases; Cytarabine; Drug-Related Side Effects and Adverse Reactions; Humans; Isotretinoin; Keratitis; Pharmaceutical Preparations; Rifabutin; Tamoxifen

2007
[Ocular toxicity induced by medication].
    Anales del sistema sanitario de Navarra, 2008, Volume: 31 Suppl 3

    Topics: Antimalarials; Antirheumatic Agents; Chloroquine; Estrogen Antagonists; Humans; Hydroxychloroquine; Tamoxifen

2008
Hydroxychloroquine: balancing the need to maintain therapeutic levels with ocular safety: an update.
    Current opinion in rheumatology, 2018, Volume: 30, Issue:3

    Topics: Antirheumatic Agents; Chloroquine; Corneal Diseases; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Humans; Hydroxychloroquine; Mass Screening; Renal Insufficiency; Retinal Diseases; Retrospective Studies; Rheumatic Diseases; Risk Factors; Tamoxifen; Tomography, Optical Coherence

2018

Other Studies

40 other study(ies) available for chloroquine and tamoxifen

ArticleYear
Isolation and biological evaluation of filiformin, plakortide F, and plakortone G from the Caribbean sponge Plakortis sp.
    Journal of natural products, 2001, Volume: 64, Issue:11

    Topics: Animals; Antimalarials; Bromobenzenes; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dioxanes; Gas Chromatography-Mass Spectrometry; Hepatitis B; HIV; Humans; Jamaica; Lactones; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Mycobacterium tuberculosis; Neoplasms, Unknown Primary; Nuclear Magnetic Resonance, Biomolecular; Plasmodium berghei; Plasmodium falciparum; Porifera; Spectrometry, Mass, Electrospray Ionization; Tumor Cells, Cultured

2001
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: biological evaluation and structure-activity relationships.
    Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4

    Topics: Animals; Chagas Disease; DNA, Protozoan; Dose-Response Relationship, Drug; Glutathione; HeLa Cells; Humans; Imidazoles; Isoquinolines; Models, Molecular; Oxidation-Reduction; Quantitative Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vitro screening of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives as antiprotozoal agents and docking studies on Trypanosoma cruzi CYP51.
    European journal of medicinal chemistry, 2016, May-04, Volume: 113

    Topics: Antiprotozoal Agents; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibroblasts; Humans; Imidazoles; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Phenylethyl Alcohol; Structure-Activity Relationship; Trypanosoma cruzi

2016
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Disease Models, Animal; Humans; Mice; Structure-Activity Relationship; Triazines; Tropolone; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2018
Potent Antimalarial 2-Pyrazolyl Quinolone
    ACS medicinal chemistry letters, 2018, Dec-13, Volume: 9, Issue:12

    Topics:

2018
Amino acid based prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents.
    Bioorganic & medicinal chemistry, 2019, 03-01, Volume: 27, Issue:5

    Topics: Amino Acids; Animals; Antimalarials; Antitubercular Agents; Cell Line; Female; Fosfomycin; Humans; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmodium berghei; Plasmodium falciparum; Prodrugs

2019
Phosphonodiamidate prodrugs of N-alkoxy analogs of a fosmidomycin surrogate as antimalarial and antitubercular agents.
    Bioorganic & medicinal chemistry letters, 2019, 05-01, Volume: 29, Issue:9

    Topics: Antimalarials; Antitubercular Agents; Cell Line; Cell Survival; Fosfomycin; Humans; Hydroxamic Acids; Mycobacterium tuberculosis; Organophosphonates; Plasmodium falciparum; Prodrugs

2019
Double prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents.
    Bioorganic & medicinal chemistry letters, 2019, 05-15, Volume: 29, Issue:10

    Topics: Antimalarials; Antitubercular Agents; Carbamates; Drug Evaluation, Preclinical; Fosfomycin; Humans; Inhibitory Concentration 50; Molecular Structure; Mycobacterium tuberculosis; Nitrofurans; Plasmodium falciparum; Prodrugs; Signal Transduction; Structure-Activity Relationship

2019
Antiplasmodial Oleanane Triterpenoids from
    Journal of natural products, 2021, 03-26, Volume: 84, Issue:3

    Topics: Antimalarials; Guinea; Molecular Structure; Oleanolic Acid; Phytochemicals; Plant Bark; Plant Roots; Plasmodium falciparum; Terminalia

2021
Corneal lipidosis in rats treated with amphiphilic cationic drugs.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:6

    Topics: Animals; Cations; Chloroquine; Chlorphentermine; Corneal Diseases; Female; Iprindole; Lipidoses; Male; Quinacrine; Rats; Rats, Inbred Strains; Tamoxifen

1983
Tamoxifen decreases drug efflux from liposomes: relevance to its ability to reverse multidrug resistance in cancer cells?
    FEBS letters, 1994, May-16, Volume: 344, Issue:2-3

    Topics: Antineoplastic Agents; Chloroquine; Cholesterol; Drug Resistance; Humans; Kinetics; Liposomes; Membrane Fluidity; Neoplasms; Phosphatidylcholines; Tamoxifen

1994
Retinal pigment epithelium cell culture as a model for evaluation of the toxicity of tamoxifen and chloroquine.
    Ophthalmic research, 1995, Volume: 27 Suppl 1

    Topics: Acetylglucosaminidase; Animals; Antimalarials; Cathepsin D; Cells, Cultured; Chloroquine; Drug Evaluation; Estrogen Antagonists; L-Lactate Dehydrogenase; Lysosomes; Pigment Epithelium of Eye; Swine; Tamoxifen

1995
Effects of tamoxifen, toremifene and chloroquine on the lysosomal enzymes in cultured retinal pigment epithelial cells.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:6

    Topics: Acetylglucosaminidase; Animals; Antimalarials; Cathepsin D; Cells, Cultured; Chloroquine; Estrogen Antagonists; Pigment Epithelium of Eye; Swine; Tamoxifen; Toremifene

1998
A comparative study of the effect of pigment on drug toxicity in human choroidal melanocytes and retinal pigment epithelial cells.
    Pigment cell research, 1999, Volume: 12, Issue:1

    Topics: Antimalarials; Antipsychotic Agents; Cell Survival; Chloroquine; Choroid; Estrogen Antagonists; Flow Cytometry; Humans; Melanins; Melanocytes; Monophenol Monooxygenase; Phagocytosis; Pigment Epithelium of Eye; Pigmentation; Pigments, Biological; Retina; Tamoxifen; Thioridazine; Ultraviolet Rays; Xenobiotics

1999
The phagocytosis of rod outer segments is inhibited by selected drugs in retinal pigment epithelial cell cultures.
    Pharmacology & toxicology, 2001, Volume: 88, Issue:1

    Topics: Animals; Cell Division; Cell Line; Cell Survival; Chloroquine; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Humans; Mitochondria; Phagocytosis; Pigment Epithelium of Eye; Rod Cell Outer Segment; Swine; Tamoxifen; Toremifene

2001
Evaluation of the cytotoxicity of selected systemic and intravitreally dosed drugs in the cultures of human retinal pigment epithelial cell line and of pig primary retinal pigment epithelial cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:2

    Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Fluorouracil; Ganciclovir; Gentamicins; Humans; Pigment Epithelium of Eye; Species Specificity; Swine; Tamoxifen; Toremifene

2002
Glutamate uptake is inhibited by tamoxifen and toremifene in cultured retinal pigment epithelial cells.
    Pharmacology & toxicology, 2002, Volume: 91, Issue:3

    Topics: Animals; Antimalarials; Cells, Cultured; Chloroquine; Estrogen Antagonists; Glutamic Acid; Humans; Pigment Epithelium of Eye; Swine; Tamoxifen; Toremifene

2002
Toxicity of selected cationic drugs in retinoblastomal cultures and in cocultures of retinoblastomal and retinal pigment epithelial cell lines.
    Neurochemical research, 2004, Volume: 29, Issue:1

    Topics: Cations; Cell Line; Cell Survival; Chloroquine; Coculture Techniques; Estrogen Receptor Modulators; Humans; Pigment Epithelium of Eye; Retinoblastoma; Tamoxifen; Toremifene

2004
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:2

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Autophagy; Cell Line, Tumor; Chloroquine; Genes, myc; Genes, p53; Lymphoma; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptors, Estrogen; Recombinant Fusion Proteins; Tamoxifen; Tumor Suppressor Protein p53

2007
Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:2

    Topics: Animals; ATP-Binding Cassette Transporters; Cattle; Cells, Cultured; Chloroquine; Cyclic AMP; Humans; Hydrogen-Ion Concentration; Lysosomes; Mice; Mice, Inbred C57BL; Mice, Knockout; Photoreceptor Cells, Vertebrate; Pigment Epithelium of Eye; Receptor, Adenosine A2A; Receptors, Adrenergic, beta; Recovery of Function; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tamoxifen

2008
Tamoxifen inhibits inward rectifier K+ 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate-channel interactions.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:2

    Topics: Animals; Cats; Cell Line; Chloroquine; Electrophysiology; Estrogen Antagonists; Heart Atria; Heart Ventricles; Humans; Ion Channel Gating; Ion Channels; Kinetics; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Raloxifene Hydrochloride; Tamoxifen; Transfection

2009
Potentiation of the mutagenicity and recombinagenicity of bleomycin in yeast by unconventional intercalating agents.
    Environmental and molecular mutagenesis, 2011, Volume: 52, Issue:2

    Topics: Amines; Animals; Benzophenones; Bleomycin; Cell Line; Chloroquine; Chlorpromazine; Cricetinae; DNA Damage; Drug Synergism; Gene Conversion; Intercalating Agents; Mefloquine; Mutagenicity Tests; Mutagens; Recombination, Genetic; Saccharomyces cerevisiae; Tamoxifen

2011
Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance.
    Cancer biology & therapy, 2011, Dec-15, Volume: 12, Issue:12

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Caveolin 1; Cell Communication; Cell Line, Tumor; Chloroquine; Coculture Techniques; Epithelial Cells; Fibroblasts; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; MCF-7 Cells; Mitochondria; Neoplasms; Oxidative Phosphorylation; Phosphoric Monoester Hydrolases; Stromal Cells; Tamoxifen; Tumor Microenvironment

2011
Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells.
    Oncotarget, 2016, Jan-12, Volume: 7, Issue:2

    Topics: Animals; Antimalarials; Antineoplastic Agents, Hormonal; Apoptosis; Autophagy; Benzamides; Blotting, Western; Breast Neoplasms; Cell Proliferation; Chloroquine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred NOD; Mice, SCID; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleoside Diphosphate Reductase; RNA, Messenger; Tamoxifen; Thiazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Combination therapies enhance immunoregulatory properties of MIAMI cells.
    Stem cell research & therapy, 2019, 12-18, Volume: 10, Issue:1

    Topics: Autophagy; B7-H1 Antigen; CD4-Positive T-Lymphocytes; Cell Proliferation; Chloroquine; Coculture Techniques; Gene Expression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Interleukin-6; Leukocytes, Mononuclear; Lymphocyte Activation; Mesenchymal Stem Cells; MicroRNAs; Tamoxifen

2019
Effects of autophagy modulators tamoxifen and chloroquine on the expression profiles of long non-coding RNAs in MIAMI cells exposed to IFNγ.
    PloS one, 2022, Volume: 17, Issue:4

    Topics: Autophagy; Chloroquine; Humans; Inflammation; Interferon-gamma; RNA, Long Noncoding; Tamoxifen

2022