chloroquine and suramin

chloroquine has been researched along with suramin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's2 (7.69)18.2507
2000's8 (30.77)29.6817
2010's10 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Figadère, B; Fournet, A; Franck, X; Hocquemiller, R; Mahieux, R; Prina, E1
Berger, H; Brun, R; Kaiser, M; Saf, R; Seebacher, W; Weis, R1
Lombardo, F; Obach, RS; Waters, NJ1
Alvarez, DE; Boiani, L; Bollini, M; Bruno, AM; Casal, JJ; Cerecetto, H; González, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A1
Glen, RC; Lowe, R; Mitchell, JB1
Haiech, J; Hibert, M; Kellenberger, E; Kuhn, I; Lobstein, A; Muller-Steffner, H; Rognan, D; Said-Hassane, F; Schuber, F; Villa, P1
Anklin, C; Bahar, M; Deng, Y; Doskotch, RW; Drew, ME; Gil, RR; He, S; Kinghorn, AD; Navarro-Vázquez, A; Pandharkar, T; Werbovetz, KA; Zhu, X1
Agarwal, H; Bahar, M; Brun, R; Cason, E; Doskotch, RW; Drew, ME; Endeshaw, M; He, S; Kaiser, M; Kinghorn, AD; Li, C; Mahasenan, KV; Munde, M; Pandharkar, T; Werbovetz, KA; Wilson, WD; Zhu, X1
Ariën, KK; Augustyns, K; Cos, P; Dirié, B; Heeres, J; Joossens, J; Lewi, PJ; Lyssens, S; Maes, L; Michiels, J; Van der Veken, P; Vanham, G; Venkatraj, M1
Brantner, A; Brun, R; Bucar, F; Faist, J; Gröblacher, B; Kaiser, M; Kalia, Y; Merino, V; Perozzo, R; Saf, R; Scapozza, L; Seebacher, W; Weis, R; Wolkinger, V1
Amata, E; Devine, W; Erath, J; Lee, PJ; Leed, SE; Mensa-Wilmot, K; Patel, G; Pollastri, MP; Rodriguez, A; Roncal, NE; Sciotti, RJ; Swaminathan, U; Woodring, JL1
Mattock, NM; Peters, W1
Buyst, H1
Courtois, Y; Mascarelli, F; Tassin, J1
Flesch, IE; Kaufmann, SH1
Barrett-Connor, E1
Busch, U; Korolenko, TA; Schneider, P1
Martins, IJ; Redgrave, TG; Vermeulen, R1
HARTENSTEIN, H; KALLEE, E1
TELLA, A1

Reviews

2 review(s) available for chloroquine and suramin

ArticleYear
Drugs for the treatment of parasitic infection.
    The Medical clinics of North America, 1982, Volume: 66, Issue:1

    Topics: Antimony; Bithionol; Chloroquine; Diethylcarbamazine; Humans; Mebendazole; Melarsoprol; Metronidazole; Niclosamide; Niridazole; Oxamniquine; Parasitic Diseases; Pentamidine; Piperazines; Primaquine; Pyrantel Pamoate; Pyrimethamine; Suramin; Thiabendazole; Trichlorfon

1982
A review of drug-induced lysosomal disorders of the liver in man and laboratory animals.
    Microscopy research and technique, 1997, Feb-15, Volume: 36, Issue:4

    Topics: Animals; Chloroquine; Humans; Hypolipidemic Agents; Lipid Metabolism; Liver; Lysosomes; Metals; Suramin; Vinblastine

1997

Other Studies

24 other study(ies) available for chloroquine and suramin

ArticleYear
Biological evaluation of substituted quinolines.
    Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14

    Topics: Animals; Antiparasitic Agents; Cell Line; Cell Transformation, Viral; Evaluation Studies as Topic; HTLV-I Infections; Leishmania; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Trypanosoma

2004
Antiprotozoal activities of new bis-chlorophenyl derivatives of bicyclic octanes and aza-nonanes.
    Bioorganic & medicinal chemistry letters, 2006, Oct-15, Volume: 16, Issue:20

    Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds, Heterocyclic; In Vitro Techniques; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense

2006
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: biological evaluation and structure-activity relationships.
    Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4

    Topics: Animals; Chagas Disease; DNA, Protozoan; Dose-Response Relationship, Drug; Glutathione; HeLa Cells; Humans; Imidazoles; Isoquinolines; Models, Molecular; Oxidation-Reduction; Quantitative Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
    Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18

    Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids.
    Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

    Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme.
    Bioorganic & medicinal chemistry, 2010, Nov-15, Volume: 18, Issue:22

    Topics: ADP-ribosyl Cyclase 1; Animals; Binding Sites; Catalytic Domain; Computer Simulation; Enzyme Inhibitors; Flavonoids; High-Throughput Screening Assays; Humans; NAD+ Nucleosidase; Schistosoma mansoni; Schistosomicides; Structure-Activity Relationship

2010
Potent antiprotozoal activity of a novel semi-synthetic berberine derivative.
    Bioorganic & medicinal chemistry letters, 2011, May-01, Volume: 21, Issue:9

    Topics: Animals; Antiprotozoal Agents; Berberine; Chlorocebus aethiops; Disease Models, Animal; Inhibitory Concentration 50; Leishmania; Leishmaniasis; Malaria; Mice; Models, Molecular; Parasites; Plasmodium falciparum; Protozoan Infections; Trypanosoma brucei brucei; Trypanosomiasis; Vero Cells

2011
8,8-dialkyldihydroberberines with potent antiprotozoal activity.
    Journal of natural products, 2013, Mar-22, Volume: 76, Issue:3

    Topics: Animals; Antimalarials; Antiprotozoal Agents; Berberine Alkaloids; Crystallography, X-Ray; Female; Inhibitory Concentration 50; Leishmania donovani; Mice; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma

2013
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.
    Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19

    Topics: Anti-HIV Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense

2014
Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Administration, Oral; Animals; Antiprotozoal Agents; Azabicyclo Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship; Tissue Distribution; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2015
Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery.
    Journal of medicinal chemistry, 2015, Jul-23, Volume: 58, Issue:14

    Topics: Animals; Antiprotozoal Agents; Drug Discovery; Drug Evaluation, Preclinical; Growth Inhibitors; Hep G2 Cells; Humans; Parasites; Quinazolines

2015
The experimental chemotherapy of leishmaniasis. II. The activity in tissue culture of some antiparasitic and antimicrobial compounds in clinical use.
    Annals of tropical medicine and parasitology, 1975, Volume: 69, Issue:3

    Topics: Aminoquinolines; Animals; Anti-Bacterial Agents; Antimalarials; Antimony; Antiprotozoal Agents; Ascitic Fluid; Cell Line; Chloroquine; Cricetinae; Culture Techniques; Dogs; Drug Evaluation, Preclinical; Folic Acid Antagonists; Leishmania; Niridazole; Pentamidine; Primaquine; Quinacrine; Quinine; Sarcoma; Sulfonamides; Sulfones; Suramin

1975
The treatment of T. rhodesiense sleeping sickness, with special reference to its physio-pathological and epidemiological basis.
    Annales de la Societe belge de medecine tropicale, 1975, Volume: 55, Issue:2

    Topics: Arsenicals; Chloroquine; Humans; Melarsoprol; Proguanil; Suramin; Trypanosomiasis, African; Zambia

1975
Effect of FGFs on adult bovine Muller cells: proliferation, binding and internalization.
    Growth factors (Chur, Switzerland), 1991, Volume: 4, Issue:2

    Topics: Animals; Binding, Competitive; Cattle; Cell Division; Cells, Cultured; Chloroquine; Cross-Linking Reagents; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Heparin; Neuroglia; Phorbol Esters; Protamines; Receptors, Cell Surface; Receptors, Fibroblast Growth Factor; Retina; Suramin

1991
Attempts to characterize the mechanisms involved in mycobacterial growth inhibition by gamma-interferon-activated bone marrow macrophages.
    Infection and immunity, 1988, Volume: 56, Issue:6

    Topics: Animals; Antibiosis; Bone Marrow Cells; Butylamines; Chloroquine; Female; Free Radicals; Interferon-gamma; Macrophage Activation; Mice; Mice, Inbred C57BL; Mycobacterium bovis; Mycobacterium tuberculosis; Oxygen; Polyglutamic Acid; Recombinant Proteins; Suramin; Tetracaine

1988
Relative roles of mitochondrial and peroxisomal fatty acid oxidation in the metabolism of chylomicron remnants in rats and mice as assessed by a stable-isotope breath test.
    Atherosclerosis, 2000, Volume: 150, Issue:1

    Topics: Administration, Oral; Animals; Breath Tests; Carbon Dioxide; Carbon Isotopes; Chloroquine; Cholesterol Esters; Chylomicrons; Epoxy Compounds; Fat Emulsions, Intravenous; Fatty Acids; Hepatectomy; Hydrolysis; Lactoferrin; Liver; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxidation-Reduction; Peroxisomes; Propionates; Rats; Rats, Wistar; Suramin

2000
[The effect of germanin and chloroquine (resochin) on iodine-131 metabolism in the rat].
    Nuclear-Medizin, 1960, Jul-01, Volume: 1

    Topics: Animals; Chloroquine; Iodine; Iodine Radioisotopes; Rats; Suramin

1960
CHEMOTHERAPY OF TROPICAL DISEASES.
    Current medicine and drugs, 1964, Volume: 4, Issue:10

    Topics: Amebiasis; Amebicides; Anti-Bacterial Agents; Antimalarials; Antimony; Arsenicals; Chagas Disease; Chloroquine; Dysentery, Amebic; Emetine; Humans; Iodoquinol; Leishmaniasis; Leishmaniasis, Mucocutaneous; Leishmaniasis, Visceral; Malaria; Suramin; Trypanosomiasis; Trypanosomiasis, African; United States

1964