chloroquine has been researched along with sesquiterpenes in 200 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (14.00) | 18.7374 |
| 1990's | 48 (24.00) | 18.2507 |
| 2000's | 116 (58.00) | 29.6817 |
| 2010's | 6 (3.00) | 24.3611 |
| 2020's | 2 (1.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, DQ; Dong, Y; He, H; Liu, DQ; Liu, RJ; Yang, HL; Yang, PF; Zhang, CY | 1 |
| Brewster, D; Chapman, D; Crawley, J; Greenwood, BM; Nosten, F; Waller, D; White, NJ | 1 |
| Chandiwana, S; Mharakurwa, S; Mutetwa, S; Neill, P; Simooya, O; Stein, M | 1 |
| Trigg, PI | 1 |
| Bourdeau, EF; Childs, GE; Milhous, WK; Pang, L; Wimonwattratee, T | 1 |
| Bunyaratvej, A; Butthep, P; Fucharoen, S; Yuthavong, Y | 1 |
| Gu, HM; Inselburg, J | 1 |
| Castranova, V; Van Dyke, K; Ye, ZG | 1 |
| Walter, RD | 1 |
| Kirk, RG; Lee, P; Van Dyke, K; Ye, Z | 1 |
| Druilhe, P; Gentilini, M; Stahel, E | 1 |
| Huang, WJ; Li, J | 1 |
| Chen, L; Gu, HM; Li, GD; Li, J; Qian, YL; Waki, S; Zhu, MY | 1 |
| Carroll, FI; Kepler, JA; Lee, YW; Morey, MC; Philip, A | 1 |
| Du, YL; Jiang, Q; Li, CS | 1 |
| Van Dyke, K; Wimmer, M; Ye, ZG | 1 |
| Choudhury, DS; Devi, CU; Ghosh, SK; Sharma, VP; Sinha, S | 1 |
| Chawira, AN; Peters, W; Warhurst, DC | 1 |
| Chawira, AN; Warhurst, DC | 1 |
| Peters, W | 1 |
| Beale, GH; Thaithong, S | 1 |
| Cai, XZ; He, XZ; Yang, XP; Ye, BS; Zhan, WC; Zhan, X | 1 |
| Fukamiya, N; Kiyokawa, H; Lee, KH; Musallam, HA; Pick, RO; Tani, S | 1 |
| Li, GD | 1 |
| Fu, XQ; Gao, MX; Li, GQ; Li, ZL; Liu, HP; Ye, ZG | 1 |
| Chiodini, PL; Ellis, CJ | 1 |
| Gu, HM; Peters, W; Warhurst, DC | 1 |
| Gu, HM; Lu, BF; Qu, ZX | 1 |
| Chen, KY; Lin, BY; Ye, XY; Zhang, JX; Zheng, H | 1 |
| Howells, RE | 1 |
| Cai, XZ | 1 |
| Dong, Y; Liu, D; Liu, R; Yang, H; Yang, P; Zhang, B; Zhang, C | 1 |
| Baric, RS; Bright, P; Handy, J; Peel, SA; Yount, B | 1 |
| Basco, LK; Le Bras, J | 2 |
| Chen, YD; Lin, BY; Pan, YR; Tang, WZ; Xu, B; Zhang, JX; Zheng, H | 1 |
| Avery, MA; Chandra-ngam, G; Kamchonwongpaisan, S; Yuthavong, Y | 1 |
| Fang, Y; Lin, BY; Pan, YR; Zhang, JX; Zheng, H | 1 |
| O'Brien, L; Sherman, IW; Zidovetzki, R | 1 |
| Holloway, P; Krishna, S; Pasvol, G; ter Kuile, F; White, NJ | 1 |
| Ager, AL; Canfield, CJ; Heiffer, MH; Klayman, DL; Kyle, DE; Milhous, WK; Rossan, RN; Schuster, BG; Shmuklarsky, MJ; Tang, DB | 1 |
| Alin, MH; Ashton, M; Bjorkman, A; Bwijo, BA; Kihamia, CM; Mtey, GJ; Premji, Z | 1 |
| Adams, PA; Berman, PA; Egan, TJ; Marsh, PJ; Silver, J | 1 |
| White, NJ | 1 |
| Ezedinachi, E | 1 |
| Davis, TM; Johnston, WA; Manning, LS; Skinner, TS | 1 |
| Bienzle, U; Kremsner, PG; Müller, S; Prada, J | 1 |
| Bishop, LP; Hawley, SR; Maggs, JL; O'Neill, PM; Park, BK; Storr, RC; Ward, SA | 1 |
| Meshnick, SR | 1 |
| Heppner, DG; Kawamoto, F; Nguyen, TD; Sookto, P; Trieu, NT; Wimonwattrawatee, T; Wongsrichanalai, C | 1 |
| Oduola, AM; Sowunmi, A | 1 |
| Van Dyke, K; Ye, Z | 1 |
| Alin, MH | 1 |
| Falade, CO; Fehintola, FA; Kyle, DE; Makler, MT; Milhous, WK; Oduola, AM; Ogundahunsi, OA; Omitowoju, GO; Piper, RC; Schuster, BG; Sowunmi, A | 1 |
| Cumming, JN; Park, SB; Posner, GH; Shapiro, TA; Wang, D | 1 |
| Doury, JC; Fusai, T; Pradines, B; Rogier, C; Tall, A; Trape, JF | 1 |
| Dong, Y; Huang, KG; Liao, MZ; Liu, DQ; Yang, HL; Yang, PF; Yang, YM; Zhang, CY | 1 |
| Gathmann, I; Jiao, X; Li, XW; Liu, GY; Royce, C; Shan, CO; Zhao, X | 1 |
| Kremsner, PG; Philipps, J; Radloff, PD; Wernsdorfer, W | 1 |
| Abdulla, S; Beck, HP; Felger, I; Hatz, C; Irion, A; Mull, R; Smith, T; Tanner, M | 1 |
| Abdulla, S; Beck, HP; Gathmann, I; Hatz, C; Kibatala, P; Mull, R; Royce, C; Schellenberg, D; Tanner, M | 1 |
| Ambroise-Thomas, P | 1 |
| Bachi, MD; Cumming, JN; Korshin, EE; Ploypradith, P; Posner, GH; Shapiro, TA; Xie, S | 1 |
| Doury, JC; Kombila, M; Lebeau, C; Mabika Mamfoumbi, M; Mourou Mbina, JR; Owono Medang, M; Parzy, D; Pradines, B | 1 |
| Le Bras, J | 1 |
| White, N | 1 |
| Akompong, T; Ghori, N; Haldar, K; VanWye, J | 1 |
| Björkman, A; Hassan Alin, M; Wernsdorfer, WH | 1 |
| Benoit-Vical, F; Meunier, B; Robert, A | 2 |
| Chang, HL; Chang, SC; Chen, YC; Fang, CT; Hsieh, WC; Hsueh, PR; Hung, CC | 1 |
| Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC | 1 |
| Ding, DB; Li, GF; Shi, YL; Yang, JD; Zhao, JH | 1 |
| Jain, GK; Pandey, VC; Puri, SK; Singh, S; Srivastava, P | 1 |
| Caruana, SR; Cowman, AF; Kirk, K; Reed, MB; Saliba, KJ | 1 |
| Fusai, T; Mosnier, J; Parzy, D; Pradines, B; Rogier, C; Spiegel, A; Tall, A; Trape, JF | 1 |
| Dalvi, SS; Gogtay, NJ; Kshirsagar, NA; Rajgor, D; Wakde, M | 1 |
| Bhatt, AD; Chogle, AR; Dalvi, SS; Garg, MR; Gathmann, I; Gogtay, NJ; Kshirsagar, NA; Marathe, SN; Moorthy, NS; Mull, R; Sane, SP; Sorabjee, JS; Tilve, GH | 1 |
| Agbenyega, T; Agranoff, D; Appiah, JA; Bedu-Addo, G; Krishna, S; Mansor, SM; Navaratnam, V; Owusu-Ofori, AK; Planche, T; Ramanathan, S; Woodrow, C | 1 |
| Bloland, PB; Ettling, M; Meek, S | 1 |
| Ikemoto, N; Ishizuka, Y; Kim, HS; Ko, N; Kobayashi, M; Murakami, N; Shibata, Y; Sugimoto, M; Wataya, Y | 1 |
| Coleman, R; Doherty, T; Jawara, M; Targett, G; von Seidlein, L; Walraven, G | 1 |
| Coleman, R; Deen, J; Doherty, T; Drakeley, C; Jawara, M; Milligan, P; Pinder, M; Sutherland, C; Targett, G; von Seidlein, L; Walraven, G | 1 |
| Ager, AL; Andersen, SL; Angerhofer, CK; Grace, JM; Hu, JK; Vennerstrom, JL; Wesche, DL; Wongpanich, V | 1 |
| Etchegorry, MG; Galinski, M; Matthys, F; Nosten, F; White, NJ | 1 |
| Ariey, F; Jambou, R; Raharimalala, LA; Randrianarivelojosia, M; Randrianasolo, L; Rason, MA; Ratsimbasoa, A | 1 |
| Adabayeri, V; Akanmori, BD; Asare-Odei, G; Goka, BQ; Kurtzhals, J; Neequaye, J; Ofori-Adjei, D; Ofori-Adjei, E; Quarshie, B | 1 |
| Takeuchi, T | 1 |
| Angerhofer, CK; Cordell, GA; Han, J; Kim, SU; Lee, JG; Min, SS; Park, SH | 1 |
| Ishiyama, A; Kohana, A; Manabe, C; Omura, S; Otoguro, K; Shiomi, K; Ui, H; Yamada, H | 1 |
| Dunbar, DC; ElSohly, MA; Khan, IA; Li, XC; Muhammad, I | 1 |
| Bringmann, G; Chimanuka, B; François, G; Heyden, YV; Holenz, J; Plaizier-Vercammen, J; Timperman, G | 1 |
| Faiz, MA; Kawamoto, F; Laoboonchai, A; Lin, K; Noedl, H; Pang, LW; Wimonwattrawatee, T; Wongsrichanalai, C | 1 |
| Kollaritsch, H; Krudsood, S; Looareesuwan, S; Noedl, H; Viriyavejakul, P; Wernsdorfer, WH; Wiedermann, G; Wilairatana, P | 1 |
| Benoit-Vical, F; Dechy-Cabaret, O; Meunier, B; Robert, A | 1 |
| Chauhan, VS; Kannan, R; Sahal, D | 1 |
| Björkman, A; Gupta, S; Mariga, ST; Thapar, MM; Wernsdorfer, WH | 1 |
| Ferreras, A; Herrera, F; Sánchez, E; Triana, L | 1 |
| Fan, B; Huang, Z; Ma, X; Wen, Y; Yang, J; Yang, Z; Zhao, W | 1 |
| Belsare, H; Patel, AB | 1 |
| Angenot, L; da Cunha, AP; de Madureira, Mdo C; De Mol, P; Frederich, M; Goffin, E; Martins, AP; Philippe, G; Tits, M; Ziemons, E | 1 |
| Christensen, J; Ekpe, P; Hägerstrand, H; Jaroszewski, JW; Jensen, TH; Olsen, CE; Sittie, AA; Staalsø, T; Staerk, D; Ziegler, HL | 1 |
| Domínguez, JN | 1 |
| de Vries, PJ; Heisterkamp, SH; Kager, PA; Le, HQ; Nguyen, NV; Nguyen, TV; Phan, GT; Tran, BQ | 1 |
| Bray, PG; Hastings, IM; Ward, SA | 1 |
| Fidock, DA; Sidhu, AB; Verdier-Pinard, D | 1 |
| Anstey, NM; Baker, J; Cheng, Q; Suprianto, S; Tjitra, E | 1 |
| Folb, P; Gumede, B; Ryffel, B | 1 |
| Gao, B; Huang, K; Yang, H | 1 |
| Faiz, MA; Hossain, MA; Miller, RS; Noedl, H; Pang, LW; Rahman, MR; Samad, R; Wongsrichanalai, C; Yunus, EB | 1 |
| Benoit-Vical, F; Camus, D; Capron, M; Delhaes, L; Meunier, B | 1 |
| Coleman, R; Drakeley, CJ; Jawara, M; Milligan, P; Obisike, U; Pinder, M; Sutherland, CJ; Targett, GA; Walraven, G | 1 |
| DAVILA, M; FUENZALIDA, JM; PERALTA, O; VARGAS, H | 1 |
| Cox-Singh, J; Davis, TM; Doan, HN; Hewitt, S; Le, DC; Nguyen, MH; Nguyen, TH; Tran, BK; Tran, QT; Vo, NP | 1 |
| Feng, XP; Liu, DQ | 1 |
| Newton, PN; Pukrittayakamee, S; Rasameesoraj, M; Silamut, K; Siriyanonda, D; Suputtamongkol, Y; Teja-Isavadharm, P; White, NJ | 1 |
| Dalvi, SS; Desai, S; Gogtay, NJ; Kadam, VS; Kamtekar, KD; Kshirsagar, NA | 1 |
| Coleman, R; Drakeley, CJ; Jawara, M; Obisike, U; Pinder, M; Sutherland, CJ; Targett, GA; Walraven, G | 1 |
| Attaran, A; Barnes, KI; Curtis, C; d'Alessandro, U; Fanello, CI; Galinski, MR; Kokwaro, G; Looareesuwan, S; Makanga, M; Mutabingwa, TK; Talisuna, A; Trape, JF; Watkins, WM | 1 |
| Barman, K; Dev, V; Phookan, S | 1 |
| Singhal, T | 1 |
| Carucci, DJ; Cooper, RA | 1 |
| Brown, ML; Geyer, JA; Terrell, JC; Trotta, RF | 1 |
| Niagia, S | 1 |
| Egan, J; Hoppe, HC; Meredith, SA; van Schalkwyk, DA; Weber, BW; Wiehart, UI | 1 |
| Fontanet, A; Looareesuwan, S; Nacher, M; Phumratanaprapin, W; Silachamroon, U; Singhasivanon, P; Wilairatana, P | 1 |
| Beg, MA; Khan, MA; Razi, ST; Smego, RA | 1 |
| Chim, P; Fandeur, T; Lim, P; Maciejewski, L; Nhem, S; Sem, R | 1 |
| Majori, G | 1 |
| Stingl, P | 1 |
| Garner, P; Omari, A | 1 |
| Basilico, N; Mondani, M; Monti, D; Olliaro, P; Parapini, S; Taramelli, D | 1 |
| Alexander, N; Alloueche, A; Drakeley, CJ; Hallett, RL; Jawara, M; Ord, R; Pinder, M; Sutherland, CJ; Targett, GA; Walraven, G | 1 |
| Annerberg, A; Barends, M; Keola, S; Khanthavong, M; Lindegårdh, N; Mayxay, M; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; White, NJ; Yapom, R | 1 |
| Kyaw, MK; Lwin, S; Savran, O; Shahmanesh, M; Smithuis, F; White, NJ | 1 |
| Chim, P; Denis, MB; Fandeur, T; Lim, C; Lim, P; Nemh, S; Poravuth, Y; Seila, S; Sem, R; Socheat, D; Tsuyuoka, R | 1 |
| Hamedi, Y; Kojima, S; Looareesuwan, S; Safa, O; Tan-ariya, P; Zare, S | 1 |
| Adams, B; Elandalloussi, LM; Smith, PJ | 1 |
| Atkin, S; Checchi, F; Ford, N; Hamour, S; Hook, C; Keus, K; Melaku, Y; Montgomery, J; Wambugu, J | 1 |
| Ampuero, J; Balkan, S; D'Alessandro, U; Denoncin, A; Dujardin, JC; Dunand, J; Fortes, F; Franco, J; Gaboulaud, V; Gillet, P; Guthmann, JP; Legros, D; Saraiva, N; Tobback, S; van Herp, M; van Overmeir, C | 1 |
| Dismukes, R; Franco-Paredes, C; Kozarsky, PE; Nicolls, D | 1 |
| Anderson, TJ; Brockman, A; Nair, S; Nosten, F; Paiphun, L; Qin, H; Singlam, S | 1 |
| Ahmad, F; Durrani, N; Graham, K; Leslie, T; Rahim, S; Rowland, M | 1 |
| Bakyaita, N; Banek, K; Dorsey, G; Kamya, MR; Kilian, A; Kironde, F; Nsobya, SL; Reingold, A; Rosenthal, PJ; Slater, M; Staedke, SG; Talisuna, A; Wabwire-Mangen, F; Yeka, A | 1 |
| Abuaku, B; Duah, N; Koram, KA; Quashie, N | 1 |
| Bangchang, KN; Chaijaroenkul, W; Mungthin, M; Ward, SA | 1 |
| Bangali, AM; Barends, M; Das, S; Faiz, AM; Kamal, M; Liem, L; Maung, UA; Peters, A; Rahman, M; Rahman, MR; van den Broek, IV | 1 |
| Agnamey, P; Brasseur, P; Cisse, M; Dumoulin, J; Gaye, O; Olliaro, P; Rigal, J; Taylor, WR | 1 |
| Garner, P; Jones, K; Taylor-Robinson, D | 1 |
| Eriksen, J; Gustafsson, LL; Minzi, OM; Nsimba, SE; Petzold, M; Sanga, AJ; Tomson, G; Warsame, MY | 1 |
| Hamer, DH; Ndhlovu, M; Rowe, AK; Snow, RW; Thea, DM; Zurovac, D | 1 |
| Akoachere, M; Becker, K; Buchholz, K; Burhenne, J; Fischer, E; Haefeli, WE; Schirmer, RH | 1 |
| Adedeji, AA; Fateye, BA; Fehintola, FA; Gbotosho, GO; Happi, TC; Oduola, AM; Sowunmi, A; Tambo, E | 1 |
| Day, NP; Newton, PN; White, NJ | 1 |
| Baruah, S; Campbell, P; Narain, K; Rogers, CC | 1 |
| Akanmori, BD; Goka, BQ; Kurtzhals, JA; Ofori-Adjei, D; Quashie, NB | 1 |
| D'Alessandro, U; Erhart, A; Karema, C; Mupfasoni, D; Rusanganwa, E; Rwagacondo, C; Tinto, H; Van Marck, E; Van Overmeir, C; Vandoren, W | 1 |
| Arbe-Barnes, S; Brun, R; Kocken, CH; Matile, H; Scheurer, C; Thomas, AW; van der Wel, A; Wittlin, S | 1 |
| Agnamey, P; Brasseur, P; de Pecoulas, PE; Olliaro, P; Vaillant, M | 1 |
| Bourée, P | 1 |
| Krishna, S; Woodrow, CJ | 1 |
| de Radiguès, X; Diallo, KI; Diallo, M; Djimdé, A; Doumbo, O; Guthmann, JP; Maiga, H; Ngwakum, PA; Sacko, M | 1 |
| Ferdig, MT; Fidock, DA; Friedrich, O; Hayton, K; Lanzer, M; Patel, J; Rohrbach, P; Sanchez, CP; Sidhu, AB | 1 |
| Ahmed, ES; Elamin, SB; Elhassan, AH; Elmardi, KA; Malik, EM; Mannan, AA; Mohamed, TA; Mowien, RM | 1 |
| Fernández, FM; Grande Ortiz, M; Green, MD; Khounsaknalath, L; Manolin, O; Nettey, H; Newton, PN; Pamanivong, C; Villalva Rojas, O; Vongsack, L | 1 |
| Fidock, DA; Valderramos, SG | 1 |
| Azas, N; Chea, A; Elias, R; Faure, R; Hout, S; Long, C; Marcourt, L | 1 |
| Kollaritsch, H; Kyavar, L; Rojanawatsirivet, C; Sirichaisinthop, J; Wernsdorfer, G; Wernsdorfer, WH | 1 |
| Brockman, A; Chotivanich, K; Day, NP; Stepniewska, K; White, NJ | 1 |
| Congpuong, K; Na-Bangchang, K | 1 |
| Anderson, T; Barends, M; Brockman, A; Jaidee, A; Mayxay, M; Nair, S; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Sudimack, D; White, NJ | 1 |
| Keola, S; Khanthavong, M; Mayxay, M; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Taylor, AM; White, NJ | 1 |
| Benoit-Vical, F; Berry, A; Lelièvre, J | 1 |
| Cao, YM; Chen, G; Feng, H; Guo, SY; Li, DM; Liu, YJ; Ma, SH; Wang, JC; Zheng, L | 1 |
| Noe, D; Sharma, A; Toler, SM | 1 |
| Adagu, IS; Fivelman, QL; Warhurst, DC | 1 |
| Andrianina, NN; Jahevitra, M; Ménard, D; Ramiandrasoa, Z; Randriamanantena, A; Rasoarilalao, N; Ratsimbasoa, A; Raveloson, A; Tuseo, L | 1 |
| Abuaku, B; Duah, NO; Koram, KA; Quashie, NB | 1 |
| Adjei, L; Anemana, SD; Bienzle, U; Burchard, GD; Eggelte, TA; Ehrhardt, S; Kaiser, S; Mockenhaupt, FP | 1 |
| Ariey, F; Bedja, SA; Rabarijaona, LP; Randrianarivelojosia, M; Robert, V; Tall, A | 1 |
| Afonso, A; Carter, R; Cheesman, S; Cravo, P; Creasey, A; Culleton, R; do Rosario, V; Fidock, DA; Hunt, P; Logan, J; McNae, I; Sidhu, AB; Valderramos, SG | 1 |
| Sharma, VP | 1 |
| Benoit-Vical, F; Lelièvre, J; Loup, C; Meunier, B | 1 |
| Durrani, N; Kolaczinski, K; Rahim, S; Rowland, M | 1 |
| Nyunt, MM; Plowe, CV | 1 |
| Batty, KT; Davis, TM; Ilett, KF; Karunajeewa, HA; Lammey, J; Law, I; Lin, E; Mueller, I; Page-Sharp, M; Siba, P | 1 |
| Chaijaroenkul, W; Muhamad, P; Na-Bangchang, K; Pruktal, P | 1 |
| Agbowai, C; Akogbeto, M; Coosemans, M; D'Alessandro, U; Erhart, A; Gazard, D; Massougbodji, A; Menten, J; Nahum, A; van Loen, H; Van Overmeir, C | 1 |
| Bissagnene, E; Die-Kakou, H; Jansen, FH; Lesaffre, E; Penali, LK; Zattera, MJ | 1 |
| Chung, IM; Kim, MY; Moon, HI | 1 |
| Brun, R; Connolly, JD; Efange, SM; Hoye, TR; Makolo, FL; Mbah, JA; McAkam, T; Nelson, DP; Nyongbela, KD; Wirmum, CK; Wittlin, S | 1 |
| Bero, J; Frédérich, M; Ganfon, H; Gbaguidi, F; Gbenou, J; Moudachirou, M; Quetin-Leclercq, J; Tchinda, AT | 1 |
| Hou, KZ; Liu, J; Liu, YP; Qu, XJ; Wang, KF; Wu, B; Zhan, YH | 1 |
| Antheaume, C; Boyom, FF; Fongang, YF; Laatsch, H; Lenta, BN; Mba'ning, BM; Ngouela, SA; Noungoué, DT; Rosenthal, PJ; Sewald, N; Tsamo, E | 1 |
| Bauer, JO; Kouam, SF; Laatsch, H; Lamshöft, M; Ngadjui, BT; Ngouonpe, AW; Spiteller, M; Strohmann, C; Talontsi, FM | 1 |
| Avery, VM; Carroll, AR; Duffy, S; Senadeera, SPD | 1 |
| Cassera, MB; Dalal, SR; Ju, E; Kingston, DGI; Kong, CS; Latif, A; Lee, YJ; Seo, Y | 1 |
| Chen, B; Chen, Z; Jiang, T; Lai, X; Li, C; Li, Y; Liu, Y; Nie, J; Su, Z; Sun, C; Yang, H; Zheng, J; Zhuo, J | 1 |
| Ahn, SC; Kim, KY; Kim, SC; Kim, YW; Lee, HJ; Park, KI; Yeom, SH; Yun, UJ | 1 |
22 review(s) available for chloroquine and sesquiterpenes
| Article | Year |
|---|---|
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
Advances in chemotherapy.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Malaria; Plasmodium; Plasmodium falciparum; Primaquine; Sesquiterpenes; Triazines | 1982 |
The treatment of malaria.
Topics: Adult; Antimalarials; Artemisinins; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Malaria, Falciparum; Pregnancy; Prognosis; Sesquiterpenes | 1996 |
Is haemozoin a target for antimalarial drugs?
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Hemeproteins; Mice; Plasmodium; Sesquiterpenes | 1996 |
[New antimalarial drugs].
Topics: Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Approval; Drug Combinations; Drug Industry; Drug Resistance; Guidelines as Topic; Humans; Proguanil; Sesquiterpenes | 1998 |
Combination therapy for malaria in Africa: hype or hope?
Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Cross-Cultural Comparison; Half-Life; Humans; Insecticide Resistance; Malaria; Mefloquine; Pyrimethamine; Self Medication; Sesquiterpenes; Sulfadoxine; Thailand | 2000 |
[Malaria].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Diagnosis, Differential; Humans; Malaria; Prognosis; Sesquiterpenes | 2001 |
Chemotherapeutic agents against malaria: what next after chloroquine?
Topics: Animals; Antimalarials; Artemisinins; Biological Factors; Chloroquine; Folic Acid Antagonists; Humans; Malaria; Protease Inhibitors; Quinine; Sesquiterpenes | 2002 |
Chloroquine and artemisinin: six decades of research--what next?
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Genes, Protozoan; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Sesquiterpenes | 2003 |
WHO, the Global Fund, and medical malpractice in malaria treatment.
Topics: Africa; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Drug Costs; Drug Resistance; Drug Therapy, Combination; Humans; International Agencies; Malaria; Malaria, Falciparum; Malpractice; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; World Health Organization | 2004 |
Management of severe malaria.
Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Combined Modality Therapy; Developing Countries; Endemic Diseases; Exchange Transfusion, Whole Blood; Female; Humans; Incidence; India; Infant; Malaria, Falciparum; Male; Quinine; Randomized Controlled Trials as Topic; Risk Assessment; Sesquiterpenes; Severity of Illness Index; Sex Distribution | 2004 |
Proteomic approaches to studying drug targets and resistance in Plasmodium.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Computational Biology; Computers; Drug Resistance; Gene Expression Profiling; Genes, Protozoan; Genome, Protozoan; Genomics; Humans; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mass Spectrometry; Plasmodium; Plasmodium falciparum; Plasmodium vivax; Proteomics; Protozoan Proteins; Sesquiterpenes; Software | 2004 |
Emerging drug--resistance and guidelines for treatment of malaria.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Pakistan; Phenanthrenes; Plasmodium falciparum; Quinidine; Quinine; Sesquiterpenes; Time Factors | 2004 |
[Combined antimalarial therapy using artemisinin].
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2004 |
[Malaria: prophylaxis, treatment, stand-by medication. A single mosquito bite suffices].
Topics: Adult; Antimalarials; Artemether; Artemisinins; Atovaquone; Chloroquine; Climate; Doxycycline; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Male; Mefloquine; Naphthoquinones; Pregnancy; Proguanil; Risk Factors; Self Medication; Sesquiterpenes; Time Factors; Travel | 2004 |
Malaria in endemic areas.
Topics: Antimalarials; Artemether; Artemisinins; Blood Transfusion; Chloroquine; Deferoxamine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
Malaria: uncomplicated, caused by Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Proguanil; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2005 |
Antimalarial drugs: recent advances in molecular determinants of resistance and their clinical significance.
Topics: Africa; Amino Alcohols; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Biological Transport; Calcium-Transporting ATPases; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Gene Amplification; Humans; Malaria, Falciparum; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Models, Biological; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinine; Sesquiterpenes | 2006 |
Transporters involved in resistance to antimalarial drugs.
Topics: Animals; Antimalarials; Artemisinins; Calcium-Transporting ATPases; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Sodium-Hydrogen Exchangers | 2006 |
Current malaria status and distribution of drug resistance in East and Southeast Asia with special focus to Thailand.
Topics: Age Factors; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium; Quinine; Sesquiterpenes; Sex Factors; Sulfadoxine | 2007 |
Artemisinin and chloroquine: do mode of action and mechanism of resistance involve the same protagonists?
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drugs, Investigational; Humans; Malaria, Falciparum; Molecular Structure; Plasmodium falciparum; Sesquiterpenes | 2007 |
Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Bayes Theorem; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Malaria; Mefloquine; Pyrimethamine; Randomized Controlled Trials as Topic; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
38 trial(s) available for chloroquine and sesquiterpenes
| Article | Year |
|---|---|
Comparison of artemether and chloroquine for severe malaria in Gambian children.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Gambia; Humans; Injections, Intramuscular; Malaria, Falciparum; Plasmodium falciparum; Sesquiterpenes; Severity of Illness Index | 1992 |
A comparative study of the schizontocidal efficacy and safety of artemether versus chloroquine in uncomplicated malaria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Chloroquine; Female; Humans; Malaria, Falciparum; Male; Sesquiterpenes | 1992 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
Efficacy of oral and intravenous artesunate in male Tanzanian adults with Plasmodium falciparum malaria and in vitro susceptibility to artemisinin, chloroquine, and mefloquine.
Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drugs, Chinese Herbal; Erythrocytes; Humans; Injections, Intravenous; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Parasitemia; Plasmodium falciparum; Recurrence; Sesquiterpenes; Tanzania | 1995 |
In vivo efficacy of chloroquine, halofantrine, pyrimethamine-sulfadoxine and qinghaosu (artesunate) in the treatment of malaria in Calabar, Nigeria.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Nigeria; Phenanthrenes; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Time Factors; Urban Health | 1996 |
Efficacy of artemether in severe falciparum malaria in African children.
Topics: Adolescent; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 1996 |
Phase II trial in China of a new, rapidly-acting and effective oral antimalarial, CGP 56697, for the treatment of Plasmodium falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; China; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Middle Aged; Sesquiterpenes; Time Factors; Treatment Outcome | 1997 |
Distinction of recrudescences from new infections by PCR-RFLP analysis in a comparative trial of CGP 56 697 and chloroquine in Tanzanian children.
Topics: Acute Disease; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Recurrence; Sesquiterpenes; Tanzania; Time Factors; Treatment Outcome | 1998 |
Efficacy and safety of CGP 56697 (artemether and benflumetol) compared with chloroquine to treat acute falciparum malaria in Tanzanian children aged 1-5 years.
Topics: Acute Disease; Administration, Oral; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Sesquiterpenes; Tanzania; Treatment Outcome | 1998 |
A randomized, double-blind, parallel-group, comparative safety, and efficacy trial of oral co-artemether versus oral chloroquine in the treatment of acute uncomplicated Plasmodium falciparum malaria in adults in India.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Double-Blind Method; Drug Combinations; Electrocardiography; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Middle Aged; Polymerase Chain Reaction; Sesquiterpenes; Time Factors | 2000 |
Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Female; Follow-Up Studies; Ghana; Humans; Infant; Injections, Intravenous; Malaria; Malaria, Cerebral; Male; Sesquiterpenes | 2001 |
Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.
Topics: Adolescent; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Gambia; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2001 |
Comparison of chloroquine with artesunate in the treatment of cerebral malaria in Ghanaian children.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Female; Ghana; Humans; Malaria, Cerebral; Male; Plasmodium falciparum; Sesquiterpenes | 2001 |
In vivo-in vitro model for the assessment of clinically relevant antimalarial cross-resistance.
Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Models, Biological; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Recurrence; Sesquiterpenes | 2001 |
Artemisinin or chloroquine for blood stage Plasmodium vivax malaria in Vietnam.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Double-Blind Method; Drug Resistance; Female; Humans; Malaria, Vivax; Male; Middle Aged; Parasitemia; Plasmodium vivax; Sesquiterpenes; Treatment Outcome; Vietnam | 2002 |
Therapeutic efficacies of artesunate-sulfadoxine-pyrimethamine and chloroquine-sulfadoxine-pyrimethamine in vivax malaria pilot studies: relationship to Plasmodium vivax dhfr mutations.
Topics: Adolescent; Adult; Animals; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Vivax; Male; Plasmodium vivax; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2002 |
The addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children delays, but does not prevent treatment failure.
Topics: Age Factors; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Gambia; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Sesquiterpenes; Treatment Failure | 2003 |
Treatment of uncomplicated falciparum malaria in southern Vietnam: can chloroquine or sulfadoxine-pyrimethamine be reintroduced in combination with artesunate?
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Humans; Malaria, Falciparum; Male; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Vietnam | 2003 |
Artemether bioavailability after oral or intramuscular administration in uncomplicated falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Area Under Curve; Artemether; Artemisinins; Biological Assay; Biological Availability; Biotransformation; Chloroquine; Drug Resistance; Female; Humans; Injections, Intramuscular; Intestinal Absorption; Malaria, Falciparum; Male; Middle Aged; Quinine; Sesquiterpenes | 2003 |
Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes.
Topics: Acute Disease; Age Factors; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Gambia; Humans; Infant; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Prevalence; Sesquiterpenes; Treatment Failure | 2004 |
Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2004 |
Comparison of chloroquine, sulfadoxine/pyrimethamine, mefloquine and mefloquine-artesunate for the treatment of falciparum malaria in Kachin State, North Myanmar.
Topics: Adolescent; Adult; Age Distribution; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Myanmar; Pyrimethamine; Recurrence; Sesquiterpenes; Sulfadoxine; Treatment Failure | 2004 |
Therapeutic efficacy of artesunate in Plasmodium vivax malaria in Thailand.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Primaquine; Sesquiterpenes; Thailand; Treatment Outcome | 2004 |
Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Membrane Proteins; Membrane Transport Proteins; Protozoan Proteins; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2005 |
Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central Angola.
Topics: Amodiaquine; Angola; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure | 2005 |
Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum in Afghanistan.
Topics: Adolescent; Adult; Afghanistan; Aged; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasite Egg Count; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; Treatment Outcome | 2005 |
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda.
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Humans; Infant; Infections; Malaria; Male; Pyrimethamine; Risk Factors; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Uganda | 2005 |
Comparative efficacy of antimalarial drugs including ACTs in the treatment of uncomplicated malaria among children under 5 years in Ghana.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Ghana; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2005 |
Efficacy of chloroquine + sulfadoxine--pyrimethamine, mefloquine + artesunate and artemether + lumefantrine combination therapies to treat Plasmodium falciparum malaria in the Chittagong Hill Tracts, Bangladesh.
Topics: Adolescent; Antimalarials; Artemether; Artemisinins; Artesunate; Bangladesh; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2005 |
Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Fever; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Parasitemia; Polymerase Chain Reaction; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; Treatment Outcome | 2005 |
A randomized trial comparing the efficacy of four treatment regimens for uncomplicated falciparum malaria in Assam state, India.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; India; Infant; Malaria, Falciparum; Male; Mefloquine; Prospective Studies; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2006 |
Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Recurrence; Sesquiterpenes; Sulfadoxine; Treatment Failure | 2006 |
Thiamin deficiency and uncomplicated falciparum malaria in Laos.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Beriberi; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Enzyme Activation; Erythrocytes; Female; Humans; Infant; Laos; Malaria, Falciparum; Male; Middle Aged; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Thiamine Deficiency; Transketolase; Treatment Outcome | 2007 |
Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Madagascar; Malaria, Falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Efficacy of artesunate plus amodiaquine, artesunate plus sulfadoxine-pyrimethamine, and chloroquine plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union.
Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Comoros; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2007 |
Sulfadoxine-pyrimethamine plus artesunate compared with chloroquine for the treatment of vivax malaria in areas co-endemic for Plasmodium falciparum and P. vivax: a randomised non-inferiority trial in eastern Afghanistan.
Topics: Adolescent; Afghanistan; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; Humans; Malaria, Falciparum; Malaria, Vivax; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria.
Topics: Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2008 |
Adding artesunate to sulphadoxine-pyrimethamine greatly improves the treatment efficacy in children with uncomplicated falciparum malaria on the coast of Benin, West Africa.
Topics: Analysis of Variance; Anemia; Animals; Antimalarials; Artemisinins; Artesunate; Benin; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Fever; Follow-Up Studies; Humans; Infant; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Respiratory Tract Infections; Sesquiterpenes; Sulfadoxine; Time Factors; Treatment Outcome | 2007 |
141 other study(ies) available for chloroquine and sesquiterpenes
| Article | Year |
|---|---|
[Sensitivity in vitro of Plasmodium falciparum to chloroquine, pyronaridine, artesunate and piperaquine in south Yunnan].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes | 1992 |
Drug use and design in the nineties.
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine | 1991 |
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Butylated Hydroxytoluene; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Mefloquine; Molecular Structure; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Sesquiterpenes; Thailand | 1991 |
Decreased sensitivity of artesunate and chloroquine of Plasmodium falciparum infecting hemoglobin H and/or hemoglobin constant spring erythrocytes.
Topics: Animals; Artemisinins; Artesunate; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Erythrocytes; Hemoglobin H; Hemoglobins, Abnormal; Humans; Malaria; Plasmodium falciparum; Sesquiterpenes | 1989 |
Premature release of Plasmodium falciparum from swollen erythrocytes induced by some antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Azure Stains; Cells, Cultured; Chloroquine; Erythrocyte Membrane; Erythrocytes; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes | 1989 |
The potentiating action of tetrandrine in combination with chloroquine or qinghaosu against chloroquine-sensitive and resistant falciparum malaria.
Topics: Alkaloids; Animals; Antimalarials; Artemisinins; Benzylisoquinolines; Chloroquine; Drug Resistance; Drug Synergism; Malaria; Plasmodium falciparum; Sesquiterpenes; Species Specificity | 1989 |
Plasmodium falciparum: inhibition of dolichol kinase by mefloquine.
Topics: Animals; Artemisinins; Cations, Divalent; Chloroquine; Cytidine Triphosphate; Detergents; Dolichols; Egtazic Acid; Erythrocytes; Hydrogen-Ion Concentration; Kinetics; Mefloquine; Microsomes; Nucleotides; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Plasmodium falciparum; Quinolines; Sesquiterpenes; Trifluoperazine | 1986 |
X-ray microanalysis of Plasmodium falciparum and infected red blood cells: effects of qinghaosu and chloroquine on potassium, sodium, and phosphorus composition.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Electrolytes; Electron Probe Microanalysis; Erythrocytes; Humans; In Vitro Techniques; Phosphorus; Plasmodium falciparum; Potassium; Sesquiterpenes; Sodium | 1988 |
Antagonism of chloroquine with other antimalarials.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Interactions; Drug Resistance; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1988 |
[Effects of artesunate, pyronaridine and hydroxypiperaquine on chloroquine-sensitive and chloroquine-resistant isolates of Plasmodium falciparum in vitro].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes | 1988 |
Fluorometric determination of the antimalarial efficacy of artemisinin and artemether against Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Plasmodium falciparum; Sesquiterpenes; Spectrometry, Fluorescence | 1988 |
1,2,4-Trioxanes as potential antimalarial agents.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 1988 |
[Development of a qinghaosu-resistant line of Plasmodium berghei ANKA and N strain].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Microbial; Malaria; Male; Mice; Plasmodium berghei; Primaquine; Pyrans; Sesquiterpenes | 1986 |
Effect of artemisinin (qinghaosu) and chloroquine on drug-sensitive and drug-resistant strains of Plasmodium falciparum malaria: use of [2,8-3H]adenosine as an alternative to [G-3H]hypoxanthine in the assessment of in vitro antimalarial activity.
Topics: Adenosine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Malaria; Mice; Plasmodium falciparum; Sesquiterpenes | 1987 |
In vitro chloroquine resistant Plasmodium falciparum in Calcutta and its sensitivity to qinghaosu (artemisitene).
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Humans; India; Plasmodium falciparum; Sesquiterpenes | 1987 |
The efficacy of artemether (qinghaosu) in Plasmodium falciparum and P. vivax in Burma.
Topics: Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrans; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 1986 |
Qinghaosu resistance in rodent malaria.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Malaria; Male; Mice; Plasmodium; Plasmodium berghei; Sesquiterpenes | 1986 |
The effect of artemisinin combined with standard antimalarials against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Plasmodium falciparum; Sesquiterpenes | 1987 |
Susceptibility of Thai isolates of Plasmodium falciparum to artemisinine (qinghaosu) and artemether.
Topics: Animals; Artemether; Artemisinins; Chloroquine; Drug Combinations; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Thailand | 1985 |
[The combined use of artemether, sulfadoxine, pyrimethamine and primaquine in the treatment of chloroquine-resistant falciparum malaria].
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Child; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Malaria; Male; Plasmodium falciparum; Primaquine; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 1985 |
Antimalarial agents. 1. alpha-Santonin-derived cyclic peroxide as potential antimalarial agent.
Topics: Animals; Chemical Phenomena; Chemistry; Chloroquine; Drug Resistance; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Sesquiterpenes, Eudesmane | 1985 |
[Development of a piperaquine-resistant line of Plasmodium berghei K 173 strain].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes | 1985 |
Effects of Qinghaosu and chloroquine on the ultrastructure of the erythrocytic stage of P. falciparum in continuous cultivation in vitro.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Erythrocytes; Microscopy, Electron; Plasmodium falciparum; Sesquiterpenes | 1983 |
The treatment of falciparum malaria.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinidine; Quinine; Quinolines; Sesquiterpenes | 1984 |
Uptake of [3H] dihydroartemisinine by erythrocytes infected with Plasmodium falciparum in vitro.
Topics: Anisomycin; Antimalarials; Artemether; Artemisinins; Chloroquine; Erythrocytes; Humans; Plasmodium falciparum; Pyrans; Sesquiterpenes | 1984 |
[Antimalarial activities of 25 derivatives of artemisinine against chloroquine-resistant plasmodium berghei (author's transl)].
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Male; Mice; Plasmodium berghei; Pyrans; Sesquiterpenes; Structure-Activity Relationship | 1980 |
[A combined regimen of pyronaridin-artemether-chloroquine (PAC) for the treatment of Plasmodium cynomolgi infection in the rhesus monkey].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Therapy, Combination; Macaca mulatta; Malaria; Naphthyridines; Pyrans; Sesquiterpenes | 1984 |
[Observation of therapeutic effect of single-dose combined administration of Qinghaosu, sulphomethoxine, pyrimethamine and primaquine in the treatment of chloroquine-resistant malignant malaria (author's transl)].
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Middle Aged; Primaquine; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfamethazine | 1981 |
[Sensitivity of Plasmodium falciparum to seven antimalarials in China-Laos border].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes | 1995 |
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Blotting, Southern; Chloroquine; DNA Primers; DNA, Protozoan; Drug Resistance; Gene Amplification; Gene Expression; Genes, Protozoan; Mefloquine; Molecular Sequence Data; Phenanthrenes; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Quinine; RNA, Messenger; Selection, Genetic; Sequence Homology, Nucleic Acid; Sesquiterpenes | 1994 |
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives.
Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Mefloquine; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Triazines | 1994 |
[Studies on the establishment of malarial animal model of short-term relapse. IV. Short-term relapse in rhesus monkeys infected with sporozoites of Plasmodium cynomolgi].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Disease Models, Animal; Drug Therapy, Combination; Erythrocytes; Macaca mulatta; Malaria; Naphthyridines; Plasmodium cynomolgi; Recurrence; Sesquiterpenes | 1993 |
Resistance to artemisinin of malaria parasites (Plasmodium falciparum) infecting alpha-thalassemic erythrocytes in vitro. Competition in drug accumulation with uninfected erythrocytes.
Topics: alpha-Thalassemia; Animals; Antimalarials; Artemisinins; Biological Transport; Chloroquine; Drug Resistance; Erythrocytes; Hemoglobin H; Hemoglobins, Abnormal; Humans; Plasmodium falciparum; Reference Values; Sesquiterpenes | 1994 |
[Studies on the establishment of malarial animal model of short-term relapse. III. Combined therapy with pyronaridine-artemether-chloroquine for parasitemia clearance].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Disease Models, Animal; Drug Therapy, Combination; Macaca mulatta; Malaria; Naphthyridines; Plasmodium cynomolgi; Recurrence; Sesquiterpenes | 1993 |
Inhibition of Plasmodium falciparum phospholipase A2 by chloroquine, quinine, and arteether.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Erythrocytes; Humans; Hydrogen-Ion Concentration; Phospholipases A; Phospholipases A1; Phospholipases A2; Plasmodium falciparum; Quinine; Sesquiterpenes | 1993 |
In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 1993 |
Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria.
Topics: Animals; Antimalarials; Artemisinins; Cell Differentiation; Chloroquine; Drugs, Chinese Herbal; Hypoxanthine; Hypoxanthines; Lactates; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes | 1993 |
Comparison of beta-artemether and beta-arteether against malaria parasites in vitro and in vivo.
Topics: Animals; Antimalarials; Aotus trivirgatus; Artemether; Artemisinins; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Malaria; Malaria, Falciparum; Male; Mefloquine; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 1993 |
The iron environment in heme and heme-antimalarial complexes of pharmacological interest.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Heme; Hemeproteins; Hemin; Humans; Iron; Malaria; Quinine; Sesquiterpenes; Spectroscopy, Mossbauer | 1996 |
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs.
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes | 1996 |
Upregulation of reactive oxygen and nitrogen intermediates in Plasmodium berghei infected mice after rescue therapy with chloroquine or artemether.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Enzyme Induction; Female; Genetic Code; In Situ Hybridization; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitrogen Compounds; Plasmodium berghei; Reactive Oxygen Species; Sesquiterpenes; Spleen; Up-Regulation | 1996 |
Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of benzylamino and alkylamino ether analogues of artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Cell Line; Chloroquine; Drugs, Chinese Herbal; Plasmodium falciparum; Sesquiterpenes | 1996 |
In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes; Vietnam | 1997 |
Interaction of artemisinin and tetracycline or erythromycin against Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Erythromycin; Plasmodium falciparum; Protein Synthesis Inhibitors; Sesquiterpenes; Tetracycline | 1994 |
In vitro susceptibility of Tanzanian wild isolates of Plasmodium falciparum to artemisinin, chloroquine, sulfadoxine/pyrimethamine and mefloquine.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Humans; Mefloquine; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Tanzania | 1997 |
Plasmodium falciparum: evaluation of lactate dehydrogenase in monitoring therapeutic responses to standard antimalarial drugs in Nigeria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; L-Lactate Dehydrogenase; Malaria, Falciparum; Male; Monitoring, Physiologic; Nigeria; Phenanthrenes; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 1997 |
Design, synthesis, derivatization, and structure-activity relationships of simplified, tricyclic, 1,2,4-trioxane alcohol analogues of the antimalarial artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Design; Drug Evaluation, Preclinical; Heterocyclic Compounds; Plasmodium falciparum; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 1998 |
In vitro activity of artemether against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial drugs.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Erythrocytes; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Senegal; Sesquiterpenes | 1998 |
In vitro sensitivity of Plasmodium falciparum to eight antimalarials in China-Myanmar and China-Lao PDR border areas.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; China; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Laos; Microbial Sensitivity Tests; Myanmar; Naphthyridines; Plasmodium falciparum; Quinine; Sesquiterpenes | 1997 |
Follow-up of the susceptibility of Plasmodium falciparum to antimalarials in Gabon.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Follow-Up Studies; Gabon; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes; Sulfadoxine | 1998 |
Synthesis and in vitro antimalarial activity of sulfone endoperoxides.
Topics: Animals; Antimalarials; Chloroquine; Drugs, Chinese Herbal; Models, Molecular; Molecular Conformation; Molecular Structure; Peroxides; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship; Sulfones | 1998 |
In vitro susceptibility of Gabonese wild isolates of Plasmodium falciparum to artemether, and comparison with chloroquine, quinine, halofantrine and amodiaquine.
Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Gabon; Humans; Infant; Malaria, Falciparum; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 1998 |
In vitro susceptibility of African Plasmodium falciparum isolates to dihydroartemisinin and the risk factors for resistance to qinghaosu.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Evaluation, Preclinical; Drug Resistance; France; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes; Travel | 1998 |
Antimalarial drug resistance and combination chemotherapy.
Topics: Animals; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Sesquiterpenes | 1999 |
Artemisinin and its derivatives are transported by a vacuolar-network of Plasmodium falciparum and their anti-malarial activities are additive with toxic sphingolipid analogues that block the network.
Topics: Animals; Antimalarials; Artemisinins; Biological Transport; Chloroquine; Drug Resistance; Drug Synergism; Erythrocytes; Fluorescent Antibody Technique, Indirect; Humans; Malaria, Falciparum; Membrane Proteins; Microscopy, Electron; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Sphingolipids; Vacuoles | 1999 |
Synergism of benflumetol and artemether in Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Culture Media; Drug Resistance, Multiple; Drug Synergism; Ethanolamines; Fluorenes; Inhibitory Concentration 50; Lumefantrine; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes | 1999 |
Potentiation of artemisinin activity against chloroquine-resistant Plasmodium falciparum strains by using heme models.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Erythrocytes; Humans; Metalloporphyrins; Plasmodium falciparum; Sesquiterpenes | 1999 |
Imported malaria: successful treatment of 31 patients in the era of chloroquine resistance.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Male; Middle Aged; Primaquine; Quinine; Retrospective Studies; Sesquiterpenes; Travel | 1999 |
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes | 1999 |
Schizontocidal effects of oral artesunate on Plasmodium berghei in mice and P knowlesi in monkeys.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Female; Macaca mulatta; Malaria; Male; Mice; Plasmodium berghei; Plasmodium knowlesi; Sesquiterpenes | 1999 |
A simple and rapid evaluation of methemoglobin toxicity of 8-aminoquinolines and related compounds.
Topics: Administration, Cutaneous; Administration, Oral; Aminoquinolines; Animals; Antimalarials; Artemisinins; Cell-Free System; Chloroquine; Cytochrome-B(5) Reductase; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Macaca mulatta; Methemoglobin; Methemoglobinemia; Muridae; Oxyhemoglobins; Primaquine; Rats; Sesquiterpenes | 2000 |
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum.
Topics: Amino Acid Substitution; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Mefloquine; Mutation; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes; Verapamil | 2000 |
Antibiotics for prophylaxis of Plasmodium falciparum infections: in vitro activity of doxycycline against Senegalese isolates.
Topics: Amodiaquine; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antimalarials; Artemether; Artemisinins; Chloroquine; Doxycycline; Drug Resistance; Erythrocytes; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Scintillation Counting; Senegal; Sesquiterpenes; Statistics, Nonparametric; Triazines | 2000 |
An unusual case of multidrug-resistant Plasmodium vivax malaria in Mumbai (Bombay), India.
Topics: Adolescent; Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Humans; India; Malaria, Vivax; Male; Mefloquine; Plasmodium vivax; Primaquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2000 |
In vitro and in vivo potentiation of artemisinin and synthetic endoperoxide antimalarial drugs by metalloporphyrins.
Topics: Animals; Antimalarials; Artemisinins; Cell Line; Chloroquine; Drug Resistance; Drug Synergism; Humans; Malaria, Falciparum; Metalloporphyrins; Mice; Peroxides; Plasmodium falciparum; Sesquiterpenes | 2000 |
Potent in vivo antimalarial activity of 3,15-di-O-acetylbruceolide against Plasmodium berghei infection in mice.
Topics: Animals; Antimalarials; Artemisinins; Carbolines; Chloroquine; Dose-Response Relationship, Drug; Malaria; Male; Mice; Mice, Inbred ICR; Plasmodium berghei; Pyridones; Random Allocation; Sesquiterpenes | 2000 |
Parasitaemia and gametocytaemia after treatment with chloroquine, pyrimethamine/sulfadoxine, and pyrimethamine/sulfadoxine combined with artesunate in young Gambians with uncomplicated malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Cost-Benefit Analysis; Disease Transmission, Infectious; Drug Combinations; Female; Gambia; Gametogenesis; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Pyrimethamine; Random Allocation; Rural Health; Seasons; Sesquiterpenes; Sulfadoxine; Time Factors; Treatment Outcome | 2001 |
Assessment of the antimalarial potential of tetraoxane WR 148999.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Humans; Lactones; Malaria; Malaria, Falciparum; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Spiro Compounds; Tetraoxanes | 2000 |
Malaria epidemic in Burundi.
Topics: Antimalarials; Artemisinins; Burundi; Chloroquine; Disease Outbreaks; Drug Therapy, Combination; Humans; Malaria, Falciparum; Sesquiterpenes | 2001 |
Madagascan isolates of Plasmodium falciparum showing low sensitivity to artemether in vitro.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Confidence Intervals; Drug Resistance; Drug Therapy, Combination; Humans; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes; Statistics, Nonparametric | 2001 |
Synthesis of new artemisinin analogues from artemisinic acid modified at C-3 and C-13 and their antimalarial activity.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Chromatography, Thin Layer; Drug Resistance, Microbial; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; KB Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Structure-Activity Relationship | 2001 |
Potent antimalarial activities of polyether antibiotic, X-206.
Topics: Actinomycetales; Animals; Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Artesunate; Cell Death; Cell Line; Chloroquine; Drug Resistance; Embryo, Mammalian; Embryo, Nonmammalian; Ethers, Cyclic; Humans; Malaria; Mice; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes | 2001 |
Antimalarial (+)-trans-hexahydrodibenzopyran derivatives from Machaerium multiflorum.
Topics: Amphotericin B; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Benzopyrans; Benzoxazines; Cannabinoids; Cells, Cultured; Chloroquine; Cryptococcus neoformans; Drug Resistance, Microbial; Fabaceae; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methicillin; Molecular Conformation; Molecular Structure; Morpholines; Naphthalenes; Peru; Plant Stems; Plants, Medicinal; Plasmodium falciparum; Sesquiterpenes; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Staphylococcus aureus; Structure-Activity Relationship; Tetracycline | 2001 |
A comparison of the stage-specific efficacy of chloroquine, artemether and dioncophylline B against the rodent malaria parasite Plasmodium chabaudi chabaudi in vivo.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Female; Isoquinolines; Life Cycle Stages; Malaria; Mice; Parasitemia; Plasmodium chabaudi; Sesquiterpenes | 2001 |
In vitro susceptibility of Plasmodium falciparum isolates from Myanmar to antimalarial drugs.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes | 2001 |
Preparation and antimalarial activities of "trioxaquines", new modular molecules with a trioxane skeleton linked to a 4-aminoquinoline.
Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Citrates; Drug Resistance; In Vitro Techniques; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 2000 |
Heme-artemisinin adducts are crucial mediators of the ability of artemisinin to inhibit heme polymerization.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Heme; Plasmodium yoelii; Polymers; Protein Binding; Proteins; Sesquiterpenes | 2002 |
Plasmodium falciparum: in vitro interactions of artemisinin with amodiaquine, pyronaridine, and chloroquine.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Interactions; Drug Resistance; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes | 2002 |
Effect of antimalarial drugs on plasmodia cell-free protein synthesis.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Electrophoresis, Polyacrylamide Gel; Plasmodium falciparum; Primaquine; Protein Biosynthesis; Protein Synthesis Inhibitors; Protozoan Proteins; RNA, Messenger; Sesquiterpenes | 2002 |
[In vitro sensitivity of Plasmodium falciparum to chloroquine, piperaquine, pyronaridine and artesunate in Yuxi prefecture of Yunnan province].
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; In Vitro Techniques; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes | 1998 |
Resistant malaria in a neonate.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant, Newborn; Malaria, Falciparum; Mefloquine; Quinine; Risk Assessment; Sesquiterpenes; Severity of Illness Index; Treatment Outcome | 2002 |
In vitro antiplasmodial activity of Tithonia diversifolia and identification of its main active constituent: tagitinin C.
Topics: Animals; Antimalarials; Asteraceae; Chloroquine; Humans; Inhibitory Concentration 50; Plant Extracts; Plasmodium falciparum; Sesquiterpenes; Tumor Cells, Cultured | 2002 |
Possible artefacts in the in vitro determination of antimalarial activity of natural products that incorporate into lipid bilayer: apparent antiplasmodial activity of dehydroabietinol, a constituent of Hyptis suaveolens.
Topics: Abietanes; Animals; Antimalarials; Artifacts; Biological Products; Cell Size; Chloroquine; Diterpenes; Erythrocytes; Humans; Inhibitory Concentration 50; Lamiaceae; Lipid Bilayers; Microscopy, Electron; Plasmodium falciparum; Sesquiterpenes; Tumor Cells, Cultured | 2002 |
Parasitology. A requiem for chloroquine.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Drug Tolerance; Evolution, Molecular; Genes, Protozoan; Humans; Malaria, Falciparum; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Tetrahydrofolate Dehydrogenase | 2002 |
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.
Topics: Alleles; Amodiaquine; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Genes, Protozoan; Haplotypes; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine; Sesquiterpenes; Transfection; Verapamil | 2002 |
Oral artesunate prevents Plasmodium berghei Anka infection in mice.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Therapy, Combination; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Plasmodium berghei; Sesquiterpenes | 2003 |
[Comparison of sensitivity of artesunate-sensitive and artesunate-resistant Plasmodium falciparum to chloroquine and amodiaquine].
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Drug Synergism; Plasmodium falciparum; Sesquiterpenes | 1999 |
Drug-resistant malaria in Bangladesh: an in vitro assessment.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Bangladesh; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes | 2003 |
[Treatment of intestinal amebiasis with chloroquine with bismuth glycolylarsanilate and with fumagillin].
Topics: Amebiasis; Anti-Bacterial Agents; Arsenicals; Bismuth; Chloroquine; Cyclohexanes; Dysentery, Amebic; Fatty Acids, Unsaturated; Sesquiterpenes | 1955 |
[Factors affecting the in vitro microtest for drug sensitivity of Plasmodium falciparum].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood; Chloroquine; Humans; Malaria, Falciparum; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes | 2003 |
A cost-effectiveness analysis of three antimalarial treatments for acute, uncomplicated Plasmodium falciparum malaria in Mumbai, India.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Combinations; Economics, Pharmaceutical; Ethanolamines; Female; Fluorenes; Hospitalization; Humans; India; Malaria, Falciparum; Male; Mefloquine; Sesquiterpenes | 2003 |
Therapeutic efficacies of antimalarial drugs in the treatment of uncomplicated, Plasmodium falciparum malaria in Assam, north-eastern India.
Topics: Adolescent; Adult; Aged; Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; India; Infant; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfanilamide; Sulfanilamides; Ultraviolet Rays | 2004 |
Ghana battles drug-resistant malaria with artesunate.
Topics: Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Malaria; Sesquiterpenes | 2004 |
Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparum.
Topics: Ammonium Chloride; Animals; Antimalarials; Artemisinins; Biotin; Blotting, Western; Chloroquine; Dextrans; Endocytosis; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Hemoglobins; Mefloquine; Microscopy, Electron; Microscopy, Fluorescence; Monensin; Plasmodium falciparum; Quinolones; Sesquiterpenes; Transport Vesicles; Vacuoles | 2004 |
Comparison of artesunate and chloroquine activities against Plasmodium vivax gametocytes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemisinins; Artesunate; Carrier State; Child; Child, Preschool; Chloroquine; Female; Humans; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Risk Assessment; Sesquiterpenes | 2004 |
The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Sesquiterpenes | 2004 |
Evidence that haem iron in the malaria parasite is not needed for the antimalarial effects of artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Carbon Monoxide; Chloroquine; Erythrocytes; Heme; Hemoglobins; Humans; Iron; Malaria; Oxidation-Reduction; Oxidative Stress; Oxygen; Plasmodium falciparum; Sesquiterpenes | 2004 |
Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes.
Topics: Alleles; Animals; Anopheles; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Drug Resistance; Drug Therapy, Combination; Genotype; Humans; Malaria; Membrane Proteins; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes | 2004 |
In vitro monitoring of Plasmodium falciparum susceptibility to artesunate, mefloquine, quinine and chloroquine in Cambodia: 2001-2002.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Statistics, Nonparametric | 2005 |
ATPase activity of purified plasma membranes and digestive vacuoles from Plasmodium falciparum.
Topics: Adenosine Triphosphatases; Animals; Antimalarials; Artemisinins; Cell Membrane; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Subcellular Fractions; Vacuoles | 2005 |
Neurotoxicity due to antimalarial therapy associated with misdiagnosis of malaria.
Topics: Adult; Antimalarials; Anxiety; Artemisinins; Artesunate; Ataxia; Chloroquine; Diagnostic Errors; Humans; Malaria; Male; Sesquiterpenes; Tremor | 2005 |
Are transporter genes other than the chloroquine resistance locus (pfcrt) and multidrug resistance gene (pfmdr) associated with antimalarial drug resistance?
Topics: Animals; Antimalarials; Artemisinins; Artesunate; ATP-Binding Cassette Transporters; Chloroquine; Drug Resistance; Genes, MDR; Genes, Protozoan; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Sesquiterpenes | 2005 |
In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Thailand; Time Factors | 2005 |
Economic evaluation of a policy change from single-agent treatment for suspected malaria to artesunate-amodiaquine for microscopically confirmed uncomplicated falciparum malaria in the Oussouye District of south-western Senegal.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Health Care Costs; Health Policy; Humans; Infant; Malaria, Falciparum; Male; Quinine; Rural Health; Senegal; Sesquiterpenes | 2005 |
Adoption of the new antimalarial drug policy in Tanzania--a cross-sectional study in the community.
Topics: Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Therapy, Combination; Female; Focus Groups; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Malaria, Falciparum; Male; Patient Acceptance of Health Care; Population Surveillance; Pyrimethamine; Rural Health; Self Administration; Sesquiterpenes; Sulfadoxine; Tanzania | 2005 |
Treatment of paediatric malaria during a period of drug transition to artemether-lumefantrine in Zambia: cross sectional study.
Topics: Ambulatory Care; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Prescriptions; Ethanolamines; Fluorenes; Health Policy; Humans; Malaria; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Zambia | 2005 |
In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins.
Topics: Animals; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Erythrocytes; Methylene Blue; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes | 2005 |
Misattribution of central nervous system dysfunction to artesunate.
Topics: Antimalarials; Artemisinins; Artesunate; Central Nervous System Diseases; Chloroquine; Humans; Sesquiterpenes | 2005 |
Factors contributing to the development of anaemia in Plasmodium falciparum malaria: what about drug-resistant parasites?
Topics: Amodiaquine; Anemia; Animals; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria; Plasmodium falciparum; Sesquiterpenes | 2006 |
In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda.
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Multiple; Female; Humans; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Rwanda; Sesquiterpenes | 2006 |
Plasmodium vivax: in vitro susceptibility of blood stages to synthetic trioxolane compounds and the diamidine DB75.
Topics: Animals; Antimalarials; Aotidae; Artemether; Artemisinins; Artesunate; Benzamidines; Chloroquine; Drug Resistance; Heterocyclic Compounds, 1-Ring; Inhibitory Concentration 50; Malaria, Vivax; Parasitemia; Peroxides; Plasmodium falciparum; Plasmodium vivax; Sesquiterpenes; Spiro Compounds; Time Factors | 2006 |
Plasmodium falciparum in vitro susceptibility to antimalarial drugs in Casamance (southwestern Senegal) during the first 5 years of routine use of artesunate-amodiaquine.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Plasmodium falciparum; Sesquiterpenes | 2006 |
[Malaria: a medical and economic problem].
Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Health Care Costs; Humans; Lumefantrine; Malaria, Falciparum; Naphthoquinones; Proguanil; Sesquiterpenes; Survival Rate; World Health Organization | 2006 |
Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum.
Topics: Aniline Compounds; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Biological Transport, Active; Cell Membrane Permeability; Chloroquine; Drug Resistance; Erythrocytes; Fluorescent Dyes; Genetic Linkage; In Vitro Techniques; Intracellular Membranes; Lactones; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Sesquiterpenes; Substrate Specificity; Vacuoles; Xanthenes | 2006 |
From chloroquine to artemisinin-based combination therapy: the Sudanese experience.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Policy; Humans; Lumefantrine; Malaria, Falciparum; Product Surveillance, Postmarketing; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Time Factors | 2006 |
Use of refractometry and colorimetry as field methods to rapidly assess antimalarial drug quality.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Chromatography, High Pressure Liquid; Colorimetry; Indicators and Reagents; Quality Control; Quinine; Reference Standards; Refractometry; Sesquiterpenes; Spectrophotometry, Ultraviolet; Sulfadoxine | 2007 |
Antimalarial activity of sesquiterpene lactones from Vernonia cinerea.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; In Vitro Techniques; Lactones; Magnetic Resonance Spectroscopy; Molecular Structure; Parasitic Sensitivity Tests; Plant Extracts; Plasmodium falciparum; Reference Standards; Sensitivity and Specificity; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship; Vernonia | 2006 |
In vitro interaction between artemisinin and chloroquine as well as desbutyl-benflumetol in Plasmodium vivax.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Ethanolamines; Fluorenes; Humans; In Vitro Techniques; Parasitic Sensitivity Tests; Plasmodium vivax; Sesquiterpenes; Thailand | 2006 |
Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC50 values using a Bayesian approach.
Topics: Algorithms; Animals; Antimalarials; Artemisinins; Artesunate; Bayes Theorem; Chloroquine; Computer Simulation; Dose-Response Relationship, Drug; Drug Resistance; False Positive Reactions; Inhibitory Concentration 50; Mefloquine; Models, Biological; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes | 2007 |
In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Protozoan Proteins; Sesquiterpenes | 2007 |
Plasmodium yoelii: influence of antimalarial treatment on acquisition of immunity in BALB/c and DBA/2 mice.
Topics: Animals; Antibodies, Protozoan; Antimalarials; Artemisinins; Artesunate; Chloroquine; Female; Immunoglobulin G; Interferon-gamma; Malaria; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Parasitemia; Plasmodium yoelii; Recurrence; Sesquiterpenes | 2007 |
Selective enhancement of cellular oxidative stress by chloroquine: implications for the treatment of glioblastoma multiforme.
Topics: Animals; Artemisinins; Brain Neoplasms; Chloroquine; Cyclic N-Oxides; Glioblastoma; Hemin; Humans; Intracellular Membranes; Iron; Lipid Peroxidation; Lysosomes; Membrane Lipids; Oxidants; Oxidation-Reduction; Oxidative Stress; Plasmodium; Radiation-Sensitizing Agents; Sesquiterpenes; Spin Labels | 2006 |
Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Antagonism; Drug Combinations; Drug Interactions; Drug Resistance; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes; Tritium | 2007 |
The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Infant; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 2007 |
Large-scale surveillance of Plasmodium falciparum crt(K76T) in northern Ghana.
Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Genes, Protozoan; Genotype; Ghana; Humans; Lactones; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Population Surveillance; Sesquiterpenes | 2007 |
Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites.
Topics: Amino Acid Sequence; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Female; Genes, Protozoan; Humans; Mice; Mice, Inbred CBA; Models, Molecular; Mutation; Parasitic Sensitivity Tests; Plasmodium chabaudi; Sesquiterpenes; Ubiquitin | 2007 |
Battling the malaria iceberg with chloroquine in India.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Delivery of Health Care; Drug Combinations; Drug Resistance; Humans; India; Malaria; Preventive Health Services; Pyrimethamine; Sesquiterpenes; Socioeconomic Factors; Sulfadoxine; Time Factors | 2007 |
Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine.
Topics: Alkylation; Animals; Antimalarials; Artemisinins; Chloroquine; Dioxanes; Heme; Hemeproteins; Plasmodium; Sesquiterpenes; Spectrophotometry, Infrared | 2007 |
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Global Health; Half-Life; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2007 |
Assessment of in vitro antimalarial interactions between dihydroartemisinin and fosmidomycin.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Fosfomycin; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Schizonts; Sesquiterpenes | 2007 |
Antiplasmodial activity of sesquiterpene lactone from Carpesium rosulatum in mice.
Topics: Animals; Animals, Outbred Strains; Antimalarials; Asteraceae; Chloroquine; Malaria; Male; Mice; Mice, Inbred ICR; Parasitemia; Plant Extracts; Plasmodium berghei; Schizonts; Sesquiterpenes | 2008 |
Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from Scleria striatinux with antiplasmodial activity.
Topics: Antimalarials; Chloroquine; Cyperaceae; Drug Resistance; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plants, Medicinal; Plasmodium falciparum; Sesquiterpenes; Stereoisomerism | 2009 |
Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum hispidum D.C.
Topics: Animals; Antimalarials; Asteraceae; Cell Line; Chloroquine; Disease Models, Animal; Female; Humans; L-Lactate Dehydrogenase; Lactones; Leishmania mexicana; Magnetic Resonance Spectroscopy; Malaria; Mice; Molecular Structure; Parasitic Sensitivity Tests; Phytotherapy; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei | 2012 |
β-Elemene induces apoptosis in human renal-cell carcinoma 786-0 cells through inhibition of MAPK/ERK and PI3K/Akt/ mTOR signalling pathways.
Topics: Adenine; Apoptosis; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Chloroquine; Extracellular Signal-Regulated MAP Kinases; Humans; Kidney Neoplasms; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Sesquiterpenes; TOR Serine-Threonine Kinases | 2012 |
Antiplasmodial sesquiterpenes from the seeds of Salacia longipes var. camerunensis.
Topics: Cameroon; Chloroquine; Disease Resistance; Erythrocytes; Humans; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Salacia; Seeds; Sesquiterpenes | 2013 |
Indolosesquiterpene alkaloids from the Cameroonian medicinal plant Polyalthia oliveri (Annonaceae).
Topics: Animals; Antimalarials; Cameroon; Chloroquine; Indole Alkaloids; Male; Molecular Structure; Myoblasts, Skeletal; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plant Bark; Plants, Medicinal; Plasmodium falciparum; Polyalthia; Polycyclic Aromatic Hydrocarbons; Rats; Sesquiterpenes | 2014 |
Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana.
Topics: Antimalarials; Australia; Cell Survival; Chloroquine; Drug Resistance; Flowers; HEK293 Cells; Humans; Ketones; Magnetic Resonance Spectroscopy; Molecular Conformation; Myrtaceae; Plant Extracts; Plasmodium falciparum; Sesquiterpenes | 2017 |
Antimalarial activity of the isolates from the marine sponge Hyrtios erectus against the chloroquine-resistant Dd2 strain of Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Inhibitory Concentration 50; Molecular Structure; Plasmodium falciparum; Porifera; Quinones; Sesquiterpenes | 2018 |
Patchouli alcohol protects against chronic unpredictable mild stress-induced depressant-like behavior through inhibiting excessive autophagy via activation of mTOR signaling pathway.
Topics: Animals; Antidepressive Agents; Autophagy; Behavior, Animal; Chloroquine; Depression; Disks Large Homolog 4 Protein; Hippocampus; Intracellular Signaling Peptides and Proteins; Male; Microtubule-Associated Proteins; Phosphorylation; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Sequestosome-1 Protein; Sesquiterpenes; Signal Transduction; Sirolimus; Stress, Psychological; Synapsins; TOR Serine-Threonine Kinases | 2020 |
Inhibition of Autophagy Promotes Hemistepsin A-Induced Apoptosis via Reactive Oxygen Species-Mediated AMPK-Dependent Signaling in Human Prostate Cancer Cells.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Lactones; Male; Mice; PC-3 Cells; Prostatic Neoplasms; Reactive Oxygen Species; Sesquiterpenes; Signal Transduction; Xenograft Model Antitumor Assays | 2021 |