chloroquine has been researched along with quinine in 794 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 378 (47.61) | 18.7374 |
| 1990's | 159 (20.03) | 18.2507 |
| 2000's | 152 (19.14) | 29.6817 |
| 2010's | 90 (11.34) | 24.3611 |
| 2020's | 15 (1.89) | 2.80 |
| Authors | Studies |
|---|---|
| Genther, CS; Smith, CS | 1 |
| Angerhofer, CK; König, GM; Pezzuto, JM; Sticher, O; Wright, AD | 1 |
| Klayman, DL; Lee, M; Lin, AJ | 1 |
| Angerhofer, CK; Chai, H; Cordell, GA; Hu, SF; Lin, J; Lin, LZ; Pezzuto, JM; Zaw, K; Zheng, DM | 1 |
| Denny, WA; Figgitt, DP; Gamage, SA; Ralph, RK; Tepsiri, N; Wilairat, P; Wojcik, SJ | 1 |
| Angerhofer, CK; Chai, H; Cordell, GA; Likhitwitayawuid, K; Pezzuto, JM; Ruangrungsi, N | 2 |
| Cabral, JA; McChesney, JD; Milhous, WK | 1 |
| Angerhofer, CK; Cordell, GA; Likhitwitayawuid, K; Pezzuto, JM; Ruangrungsi, N | 1 |
| Angerhofer, CK; Desqueyroux-Faúndez, R; Greenidge, P; König, GM; Linden, A; Wright, AD | 1 |
| Angerhofer, CK; Böhlke, M; Farnsworth, NR; Guinaudeau, H; Mora, GA; Poveda, LJ; Soejarto, DD; Wongpanich, V | 1 |
| Angerhofer, C; Arnason, JT; Durst, T; Gbeassor, M; MacKinnon, S; Pezzuto, J; Poveda, LJ; Sanchez-Vindas, PE | 1 |
| Cimanga, K; De Bruyne, T; Pieters, L; Turger, CA; Vlietinck, AJ | 1 |
| Fushiya, S; Murata, K; Oshima, Y; Takano, F | 1 |
| Angerhofer, CK; Cordell, GA; Guinaudeau, H; Pezzuto, JM; Wongpanich, V | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Angenot, L; Brandt, V; De Pauw, M; DeMol, P; Frédérich, M; Hayette, M; Penelle, J; Prosperi, C; Tits, M | 1 |
| Jomaa, H; Mitsch, A; Schlitzer, M; Wiesner, J; Wissner, P | 1 |
| Do, TT; Fong, HH; Ghee, TT; Le, MH; Le, TX; Nguyen, MC; Nguyen, VH; Pezzuto, JM; Soejarto, DD; Tamez, PA; Vu, DH; Zhang, HJ | 1 |
| Angerhofer, CK; Cordell, GA; Han, J; Kim, SU; Lee, JG; Min, SS; Park, SH | 1 |
| Jomaa, H; Kettler, K; Schlitzer, M; Wiesner, J | 1 |
| Ihara, M; Inoue, H; Kim, HS; Shishido, T; Suzuki, M; Takasu, K; Wataya, Y | 1 |
| Choi, WS; Choi, YJ; Huh, SC; Huh, TL; Kim, DY; Kim, JE; Kim, MH; Kim, SM; Lee, BJ; Lee, SE; Park, BS; Park, E-; Rosenthal, PJ; Suh, KH | 1 |
| Malan, SF; Uys, AC; van Dyk, S; van Zyl, RL | 1 |
| Ager, A; Alvim-Gaston, M; Avery, MA; Charman, W; Peters, W; Robinson, BL; Vroman, JA; Wu, B | 1 |
| Jomaa, H; Krämer, O; Mitsch, A; Schlitzer, M; Wiesner, J; Wissner, P | 1 |
| Angenot, L; De Mol, P; Delaude, C; Frédérich, M; Jacquier, MJ; Philippe, G; Thépenier, P; Tits, M; Zèches-Hanrot, M | 1 |
| Jomaa, H; Mitsch, A; Schlitzer, M; Wiesner, J | 1 |
| Armas, MG; Deharo, E; del Olmo, E; Giménez, A; López, JL; Oporto, P; San Feliciano, A; Ybarra, M | 1 |
| Galanakis, D; Ganellin, CR | 1 |
| Brun, R; Cimanga, K; Dommisse, R; Hostyn, S; Kaiser, M; Lemière, G; Maes, BU; Mátyus, P; Pieters, L; Van Miert, S; Vlietinck, A | 1 |
| Bohle, DS; Fotie, J; Georges, E; Leimanis, ML; Nkengfack, AE; Rukunga, G | 1 |
| Fujimoto, K; Hye-Sook, K; Kakuta, H; Kourai, H; Morisaki, D; Namba, T; Sasaki, K; Wataya, Y; Yoshida, M | 1 |
| Angerhofer, CK; de Nys, R; Gurrath, M; Pezzuto, JM; Wright, AD | 1 |
| Fukuda, M; Jongsakul, K; Knirsch, C; Krudsood, S; Leowattana, W; Looareesuwan, S; Miller, RS; Noedl, H; Ohrt, C; Sriwichai, S; Tangpukdee, N; Thanachartwet, W; Yingyuen, K | 1 |
| Baniecki, ML; Clardy, J; Wirth, DF | 1 |
| Dennull, RA; Gerena, L; Johnson, JD; Lopez-Sanchez, M; Roncal, NE; Waters, NC | 1 |
| Dodean, RA; Gard, GL; Kelly, JX; Peyton, D; Riscoe, MK; Winter, RW | 1 |
| Egan, TJ; Hoppe, HC; Joiner, KA; Roberts, L | 1 |
| Acharya, BN; Kaushik, MP; Saraswat, D | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Desai, SA; Fay, MP; Furuya, T; Gluzman, IY; Goldberg, DE; Kambhampati, S; Lisk, G; Pain, M; Su, XZ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Krungkrai, J; Krungkrai, SR; Supuran, CT | 1 |
| Bambal, RB; Bates, M; Berry, N; Biagini, GA; Bonar-Law, R; Bray, PG; Brigandi, RA; Davis, CB; Gargallo, DV; Gibbons, P; Gomez-delas-Heras, FM; Gresham, SL; Hart, TK; Hindley, S; Lawrence, RM; Maggs, JL; Mukhtar, A; O'Neill, PM; Park, BK; Roberts, P; Shone, AE; Stocks, PA; Ward, SA; Winstanley, PA | 1 |
| Bacon, DJ; Escalante, AA; Griffing, SM; Haley, R; Lucas, C; McCollum, AM; Salas, C; Santolalla, M; Soberon, V; Tsukayama, P; Udhayakumar, V | 1 |
| Alumasa, JN; Brodie, PJ; Callmander, MW; Cao, S; Hou, Y; Kingston, DG; Rakotobe, EA; Rasamison, VE; Ratovoson, F; Ratsimbason, M; Roepe, PD | 1 |
| Asadollahy, E; Bambal, RB; Bates, M; Berry, N; Biagini, G; Bray, PG; Brigandi, RA; Davies, J; Davis, CB; Gargallo, DV; Gomez-de-Las-Heras, FM; Gresham, SL; Hall, C; Hindley, S; Lander, H; Maggs, JL; Nixon, G; O'Neill, PM; Parapini, S; Park, BK; Rimmer, K; Roberts, P; Shone, AE; Stanford, D; Stocks, PA; Taramelli, D; Vivas, L; Ward, SA; Winstanley, PA | 1 |
| Almeras, L; Amalvict, R; Baret, E; Briolant, S; Fusaï, T; Henry, M; Parquet, V; Pradines, B; Rogier, C; Torrentino-Madamet, M | 1 |
| Masseno, V; Muriithi, S; Nzila, A | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Fuehrer, HP; Haque, R; Hofecker, V; Khan, WA; Ley, B; Noedl, H; Siedl, A; Starzengruber, P; Thriemer, K; Wernsdorfer, WH | 1 |
| Andrianaranjaka, V; Andriantsoanirina, V; Bouchier, C; Durand, R; Jahevitra, M; Ménard, D; Mercereau-Puijalon, O; Rabarijaona, LP; Rabearimanana, S; Radrianjafy, R; Randriantsoa, T; Rason, MA; Ratsimbasoa, A; Tichit, M | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Ane, M; Baziard-Mouysset, G; El Hage, S; Marjorie, M; Payard, M; Stigliani, JL; Vial, H | 1 |
| Anquetin, G; Biot, C; Dive, D; Dubar, F; Khalife, J; Pradines, B | 1 |
| Choo, YM; Doerksen, RJ; Gertsch, J; Hamann, MT; Jacob, MR; Khan, SI; Kudrimoti, S; Madgula, V; Mayer, AM; Odde, S; Peng, J; Pennaka, HK; Prasanna, S; Rao, KV; Tekwani, BL; Tu, LC; Wang, B | 1 |
| Greenhouse, B; Joloba, M; Kiggundu, M; Nanyunja, S; Nsobya, SL; Rosenthal, PJ | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Biot, C; Brun, R; Chavain, N; Davioud-Charvet, E; Friebolin, W; Herold-Mende, C; Lanzer, M; Maes, L; Pradines, B; Tóth, K; Wang, Y; Wenzel, NI; Yardley, V | 1 |
| Borrmann, S; Kiara, SM; Mwai, L; Nzila, A; Ochola, LI; Ohuma, E; Okombo, J; Pole, L; Rono, J | 1 |
| Amalvict, R; Baret, E; Briolant, S; Didillon, E; Henry, M; Oeuvray, C; Pradines, B; Rogier, C | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Carvalho, L; Castanys, S; Gamarro, F; Manzano, JI; Pérez-Victoria, JM | 1 |
| Azam, A; Hayat, F; Moseley, E; Salahuddin, A; Van Zyl, RL | 1 |
| Balzarini, J; Bharatam, PV; Chibale, K; Kaur, H; Little, S; Singh, K | 1 |
| Dinio, T; Gorka, AP; McGinniss, A; Morgan, JB; Roepe, PD | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| de Dios, A; Gorka, AP; Roepe, PD | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Keller, PA; Mahalingam, S; Rashad, AA | 1 |
| Gut, J; Kumar, V; Raj, R; Rosenthal, PJ; Singh, P | 1 |
| Kalaria, PN; Raval, DK; Satasia, SP | 1 |
| Karad, SC; Purohit, VB; Raval, DK | 1 |
| D'hooghe, M; Vandekerckhove, S | 1 |
| Aroonkit, P; Krajangsri, S; Mungthin, M; Ruchirawat, S; Thongsornkleeb, C; Tummatorn, J | 1 |
| Karad, SC; Purohit, VB; Raval, DK; Thakkar, VR; Thakor, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Sankar, C; Umamatheswari, S | 1 |
| Ibezim, A; Kumar, NM; Okafor, S; Okoro, UC; Ugwu, DI; Ukoha, PO | 1 |
| Feng, LS; Gao, C; Hu, YQ; Wu, X; Xu, L; Xu, Z; Zhang, S; Zhao, F | 1 |
| Bhatt, JD; Chudasama, CJ; Dixit, BC; Dixit, RB; Patel, BD; Patel, TS; Patel, UH; Vanparia, SF | 1 |
| Higuchi, T; Hisamatsu, Y; Ishikawa, H; Kato, K; Kato, N; Kim, HS; Kobayashi, Y; Omiya, H; Sakata, Y; Satoh, T; Tomita, Y; Umezawa, N; Wataya, Y; Yabunaka, K; Yagi, H | 1 |
| Bane, CE; Black, C; Butler, K; Caridha, D; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Huezo, SJ; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Nolan, C; Olmeda, R; Potter, B; Pou, S; Rasmussen, SA; Read, L; Riscoe, MK; Roncal, N; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Stephens, MT; Tan, JC; Vesely, B; Vuong, C; Winter, RW; Xie, L; Zeng, Q; Zhang, J; Zhang, P | 1 |
| Bhatt, JD; Chudasama, CJ; Dixit, BC; Dixit, RB; Patel, BD; Patel, TS | 1 |
| Cheong, SL; Ng, CH; Tibon, NS | 1 |
| Daraji, DG; Jayanthi, S; Patel, HD; Pithawala, EA; Rajani, DP; Rajani, SD | 1 |
| Beteck, RM; Bokosi, FRB; Hoppe, HC; Khanye, SD; Laming, D; Mbaba, M; Mtshare, TE | 1 |
| Ademola, IK; Gordon, M; Karpoormath, R; Kayamba, F; Kushwaha, ND; Mahlalela, M; Malimabe, T; Mudau, PT; Nyamori, VO; Pooe, OJ; Shonhai, A; van Zyl, RL; Zininga, T | 1 |
| Agnamey, P; Azas, N; Cohen, A; Damiani, C; Dassonville-Klimpt, A; Dormoi, J; Guillon, J; Marchivie, M; Mullié, C; Pradines, B; Schneider, J; Sonnet, P; Taudon, N; Tisnerat, C; Totet, A | 1 |
| Sybirska, H | 1 |
| Horrobin, DF; Manku, MS | 2 |
| Hybels, RL | 1 |
| Schmidt, LH | 4 |
| Crosby, R; Rasco, J; Schmidt, LH; Vaughan, D | 1 |
| Hommel, M; McColm, AA; Trigg, PI | 1 |
| Cambournac, FJ | 1 |
| Hlaing, N; Htun Nyun, R; Kyi, KK; Myint, T; Tin, F; U, T | 1 |
| Hlaing, N; Tin, F | 1 |
| Scott, WA; Solomon, B | 1 |
| Degrémont, A | 1 |
| Bruce-Chwatt, LJ | 2 |
| Duursma, SA | 1 |
| Hall, AP | 3 |
| Maier, W; Piekarski, G | 1 |
| Chongsuphajaisiddhi, T; Harinasuta, T; Puangpartk, S; Subchareon, A | 1 |
| Spicer, AJ | 1 |
| Fradkin, R; Rasco, J; Schmidt, LH; Vaughan, D | 1 |
| Krebs, A | 1 |
| Mukherjee, DK; Mukherjee, K | 1 |
| Amin, NM | 1 |
| Van Poucke, G | 1 |
| François, J | 1 |
| Thomas, SC; Warhurst, DC | 3 |
| Clyde, DF; Hornick, RB; McCarthy, VC; Miller, RM | 1 |
| Aikawa, M; Einheber, A; Palmer, DM | 1 |
| Peters, W; Porter, M | 1 |
| Strube, RE | 1 |
| Allison, RG; Hahn, FE | 1 |
| Bricaire, F; Charmot, G | 1 |
| Boykin, DW; Davidson, MW; Griggs, BG; Wilson, WD | 1 |
| Bradley, DJ; Lumsden, WH; Mackay, DM; Southgate, BA | 1 |
| Montuori, WA; Most, H | 1 |
| Doberstyn, EB; Hall, AP; Nanokorn, A; Sonkom, P | 1 |
| Ryan, BP | 1 |
| Bruce-Chwatt, LJ; Marsden, PD | 1 |
| Peters, W | 7 |
| Bhoola, RL; Pillay, N | 1 |
| Mattock, NM; Peters, W | 1 |
| Ghosh, SK; Sharma, VP; Yadav, RS | 1 |
| Badoual, J | 1 |
| Ikeda, I; Kamiyama, T; Matsubara, J; Niinuma, S | 1 |
| Chutmongkonkul, M; Maier, WA; Seitz, HM | 1 |
| Havlik, I; Monteagudo, FS; van Zyl, RL | 1 |
| Giboda, M; Gutvirth, J; Hongvanthong, B; Pholsena, K; Rubik, I | 1 |
| Chuanak, N; Sookto, P; Timasarn, K; Webster, HK; Wernsdorfer, WH; Wimonwattrawatee, T; Wongsrichanalai, C | 1 |
| Brandling-Bennett, AD; Kamsteeg, H; Keuter, M; Khalumi, G; Ngwawe, W; Ronday, M; Sanders, J; Schouten, E; Veltkamp, S; Wetsteyn, JC | 1 |
| Aikawa, M; Ann, TK; Hoang, VT; Nagatake, T; Rabbege, J; Tegoshi, T | 1 |
| Fadat, G; Gardon, J; Gazin, P; Hengy, C; Jambou, R; Louis, FJ; Louis, JP; Trebucq, A | 1 |
| Bustos, MD; Ciceron, L; Danis, M; Gay, F; Gentilini, M; Pichet, C; Rojas-Rivero, L | 1 |
| Ali, FR; Ali, ME; Ibrahim, AM | 1 |
| Brasseur, P; Druilhe, P; Kouamouo, J; Moyou-Somo, R | 1 |
| Rieckmann, KH; Yeo, AE | 1 |
| Salako, LA; Sowunmi, A | 1 |
| Basco, LK; Bouchaud, O; Coulaud, JP; Farinotti, R; Gillotin, C; Gimenez, F; Le Bras, J; Rabenjarson, E; Ringwald, P | 1 |
| Mansor, S; Molyneux, ME; Taylor, TE; Thomas, CG; Wirima, JJ | 1 |
| Airede, AI | 1 |
| Masterton, RG; McKinlay, KP | 1 |
| Baudon, D; Cordoliani, G; Da Conceicao, S; Delolme, H; Doury, JC; Hovette, P; Lecamus, JL; Martet, G; Raphenon, G; Touze, JE | 1 |
| Allaouchiche, B; Biron, F; Boibieux, A; Gaussorgues, P; Gerard-Boncompain, M; Peyramond, D; Robert, D; Salord, F; Sirodot, M | 1 |
| Trigg, PI | 1 |
| Carme, B | 1 |
| Baird, JK; Bangs, MJ; Basri, H; Jones, TR; Ritonga, A | 1 |
| Clarke, JB; Kitteringham, NR; Neftel, K; Park, BK | 1 |
| Chamberland, M; Dubé, P; Duperval, R; Marcoux, JA; Pigeon, N | 1 |
| Amanuel, B; Endeshaw, Y; Seyoum, A | 1 |
| Abua, JU; Lege-Oguntoye, L; Ogala, WN; Olurinola, PF; Slotboom, AB; Werblinska, B | 1 |
| Bondi, FS | 1 |
| Sugioka, Y; Suzuki, M | 1 |
| Brandicourt, O; Carme, B; Gay, F; Gentilini, M; Turk, P | 1 |
| Bourdeau, EF; Childs, GE; Milhous, WK; Pang, L; Wimonwattratee, T | 1 |
| Le Bras, M; Mazaudier, E; Raccurt, CP; Ripert, C; Schmitt, A | 1 |
| Davidson, RN; Houston, S; Stein, CM | 1 |
| Chakrabarti, NK; Nagaraj, C; Narasimham, MV | 1 |
| Berger, M; Beytout, J; Cambon, M; Rey, M; Ringwald, P | 1 |
| Abissegue, B; Farinotti, R; Gelas, H; Ghipponi, PM; Hengy, C; Jambou, R; Le Bras, J | 1 |
| Brandicourt, O; Carme, B; Gay, F; Gentilini, M; Le Bras, J; Mbitsi, A; Moudzeo, H; Ndounga, M; Sathounkazi, C | 1 |
| Bazill, GW; Dexter, TM | 1 |
| Le Bras, J; Malhotra, K; Salmon, D; Vilde, JL | 1 |
| De Boeck, H; Maguire, PA; Sherman, IW; Zidovetzki, R | 1 |
| Andersen, BJ; Bygbjerg, IC; Pedersen, BK; Theander, TG | 1 |
| Kano, S; Matsuoka, Y; Obana, M; Suzuki, M; Waki, S; Yamakawa, H | 1 |
| Brewster, D; Craddock, C; Krishna, S; Kwiatkowski, D; Waller, D; White, NJ | 1 |
| Disu, MM; Kalonji, MW; Mbudi, PK; Pela, NN | 1 |
| Abissègue, B; Garrigue, G; Gazin, P; Gelas, H; Ghogomu, NA; Hengy, C; Jambou, R; Kouka-Bemba, D; Le Bras, J | 1 |
| Bellony, S; Claustre, J; Gay, F; Lepelletier, L; Mouchet, J; Nadire-Galliot, M; Poman, JP; Traore, BM | 1 |
| Ellis, CJ | 2 |
| Okeahialam, BN; Okeke, EN | 1 |
| de Geus, A; Diepersloot, RJ; Elshot, SR; Keuning, JJ | 1 |
| Warrell, DA | 1 |
| Belec, L; Bouree, P; Delmont, J; Georges, AJ; Quenum, B; Testa, J | 1 |
| Andriamangatiana-Rason, MD; Coulanges, P; Deloron, P; Lepers, JP; Ramanamirija, JA | 1 |
| Ndumbe, PM | 1 |
| Atiya, A; De Boeck, H; Sherman, IW; Zidovetzki, R | 1 |
| Emerole, GO; Nashiru, TO; Thabrew, MI | 1 |
| Larricart, P | 1 |
| Bunnag, D; Chittamas, S; Harinasuta, T; Looareesuwan, S; White, NJ | 1 |
| Beck, WT; Cirtain, MC; Felsted, RL; Glover, CJ; Safa, AR | 1 |
| Lwin, M; Zaw, M | 1 |
| Shute, JK; Smith, ME | 1 |
| Bonnevie, O; Cordoliani, G; Dedet, JP; Germanetto, P; Le Bras, J | 1 |
| Denis, MB; Giboda, M | 1 |
| Brandicourt, O; Brasseur, P; Druilhe, P; Kouamouo, J; Moyou-Somo, R | 1 |
| Brubaker, G; Draper, CC; Hills, M; Kilimali, VA | 1 |
| Ellis-Pegler, RB | 1 |
| Doi, H; Ishii, A; Shimono, K | 1 |
| Alban, P; Long, GW; Padre, LP; Ranoa, CP; Sangalang, R; Watt, G | 1 |
| Druilhe, P; Gentilini, M; Stahel, E | 1 |
| Birk, O; Golinski, M; Sack, J | 1 |
| Laoye, OJ; Salako, LA; Sowunmi, A | 1 |
| Bouchara, JP; Chabasse, D; De Gentile, L; Le Bras, J; Ligny, C; Rialland, X | 1 |
| Rolfe, M | 1 |
| Dunbar, EM; Ong, EL | 1 |
| Mankad, VN; Moore, RB | 1 |
| Childs, GE; Pooyindee, N; Wimonwattrawatee, T | 1 |
| Boudreau, EF; Chen, C; Childs, GE; Häusler, B; Milhous, W; Pooyindee, N; Wimonwattrawatee, T | 1 |
| Bugilimfura, L; Deloron, P; Neill, M; Ntilivamunda, A; Sexton, JD | 1 |
| Ginsburg, H; Krugliak, M | 1 |
| Björkman, A; Willcox, M | 1 |
| Charmot, G; Clair, B; Faucher, C; Girard, PM; Le Bras, J; Pichon, F; Simon, F | 1 |
| Bastien, P | 1 |
| Hioki, A; Ishizaki, T; Nakabayashi, T; Ohtomo, H; Tanabe, K | 1 |
| Davachi, F; Embonga, B; Goussard, B; Greenberg, AE; Kabote, N; Nguyen-Dinh, P | 1 |
| Buck, RL; Long, GW; Ranoa, CP; Sangalang, RP; Sy, N; Watt, G | 1 |
| Brockelman, CR; Bunnag, D; Satayavivad, J; Tan-ariya, P; Wongsawatkul, O | 1 |
| Brasseur, P; Druilhe, P; Pathe-Diallo, M | 1 |
| Biaud, JM; Calmel, MB; Clausse, JL; Deloron, P; Hatin, I; Le Bras, J; Marchais, H; Porte, J; Ramanamirija, JA; Simon, F | 1 |
| Buisson, Y; Chabiersky, M; Daly, JP; Le Bras, J; Roué, R; Saliou, P; Simon, F; Talarmin, F | 1 |
| Buregea, H; Cibanguka, J; Delacollette, C; Nkera, J | 1 |
| Bendtzen, K; Bygbjerg, IC; Svenson, M; Theander, TG | 1 |
| Doenhoff, MJ; Targett, GA | 1 |
| Baker, PB; Dronen, SC | 1 |
| Henderson, A; McCallum, J; Melia, W; Navein, J; Simon, J | 1 |
| Brandicourt, O; Brasseur, P; Danis, M; Druilhe, P; Kouamouo, J; Moyou, SR | 1 |
| Brandicourt, O; Brasseur, P; Danis, M; Diouf, F; Druilhe, P; Turk, P | 1 |
| Ginsburg, H; Krugliak, M; Zarchin, S | 1 |
| Afshar, A; Edrissian, GH; Emadi, AM; Ghorbani, M; Hajseyed-Javadi, J; Khaleghian, B; Pishva, E; Saghari, H; Shahabi, S | 1 |
| Cook, GC | 1 |
| Dini, GC | 1 |
| Aujard, Y; Gouyon, JB; Helias, JP; Jacqz, E; Pascal, A; Schlegel, N | 1 |
| Denis, MB | 1 |
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| Bouchaud, O; Durand, R; Godineau, N; Jezic, Z; Keundjian, A; Le Bras, J; Pradines, B; Ralaimazava, P | 1 |
| Jambou, R; Randrianarijaona, A; Randrianarivelojosia, M; Randrianasolo, L; Ratsimbasoa, A | 1 |
| Faiz, MA; Hossain, MA; Miller, RS; Noedl, H; Pang, LW; Rahman, MR; Samad, R; Wongsrichanalai, C; Yunus, EB | 1 |
| Ariey, F; Duchemin, JB; Harisoa, JL; Mauclere, P; Pietra, V; Rabarijaona, LP; Raharimalala, LA; Rakotomanana, F; Ranaivo, L; Randrianarivelojosia, M; Robert, V | 1 |
| Tumwesigire, S; Watson, S | 1 |
| Hoelscher, M; Löscher, T | 1 |
| Benito, A; Guerra-Neira, A; Raso, J; Roche, J | 1 |
| Bouchaud, O; Durand, R; Godineau, N; Hamane, S; Keundjian, A; Le Bras, J; Ralaimazava, P | 1 |
| Munasinghe, A; Myrick, A; Patankar, S; Wirth, DF | 1 |
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| PASTOR BOTIJA, F | 1 |
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| SRIVASTAVA, JR | 1 |
| ALVING, AS; ARNOLD, J; BEUTLER, E; CLAYMAN, CB; DERN, RJ; FLANAGAN, CL; HOCKWALD, RS | 1 |
| JINDAL, MN | 1 |
| FERNANDEZ NAFRIA, A | 1 |
| GREWAL, RS; SHARMA, ML | 1 |
| KURNICK, NB; RADCLIFFE, IE | 1 |
| BASU, PC; RAMAKRISHNAN, SP; SINGH, H; SINGH, N | 1 |
| CONTACOS, PG; MILLAR, JW; STITCHER, JE; YOUNG, MD | 1 |
| MOLENAAR, JC; VOORS, AW | 1 |
| EYLES, DE; HOO, CC; SANDOSHAM, AA; WARREN, M | 1 |
| COLLINS, WE; JEFFERY, GM; SKINNER, JC | 2 |
| COATNEY, GR; CONTACOS, PG; LUNN, JS | 1 |
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| Dev, V; Dua, VK; Gupta, NC; Phookan, S; Sharma, VP; Subbarao, SK | 1 |
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| Chaijaroenkul, W; Harnyuttanakorn, P; Mungthin, M; Na Bangchang, K; Suwandittakul, N | 1 |
| Chaijaroenkul, W; Na-Bangchang, K; Wisedpanichkij, R | 1 |
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| Ariey, F; Beck, HP; Bouth, DM; Chim, P; Chy, S; Coppee, JY; Duong, S; Fandeur, T; Genton, B; Gobert, JG; Khim, N; Kim, S; Le Bras, J; Lim, P; Mercereau-Puijalon, O; Nhem, S; Ringwald, P; Rogers, WO; Sem, R; Wongsrichanalai, C; Yi, P | 1 |
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| Andriantsoanirina, V; Bouchier, C; Bras, JL; Durand, R; Hubert, V; Ménard, D; Rabearimanana, S; Tichit, M | 1 |
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| Ariey, F; Beck, HP; Decosterd, LA; Duong, S; Genton, B; Hodel, EM; Mercier, T; Olliaro, P; Zanolari, B | 1 |
| Puri, SK; Singh, S; Srivastava, K; Srivastava, M; Srivastava, RK | 1 |
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| Berger, F; Bertani, S; Bouchier, C; Ekala, MT; Legrand, E; Mercereau-Puijalon, O; Meynard, JB; Musset, L; Péneau, J; Volney, B; Yrinesi, J | 1 |
| Barnwell, JW; Collins, WE; Galland, GG; Jeffery, GM; Nace, D; Sullivan, JS; Williams, A; Williams, T | 1 |
| Garner, P; Gelband, H; Graves, PM | 3 |
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| Alecrim, Md; Chaves, FC; Costa, MR; Hidalgo, Ade F; Magalhães, PM; Pohlit, AM; Silva, LF; Vieira, PP | 1 |
| Beeson, JG; Goodman, CD; Langer, C; McFadden, GI; Wilson, DW | 1 |
| Dwivedi, H; Pandey, SK; Rizvi, A; Saxena, JK; Tripathi, R | 1 |
| Abolghasemi, E; Davoudi, M; Moosa-Kazemi, SH; Reisi, A; Satvat, MT | 1 |
| Agarwal, SM; Avecilla, F; Azam, A; Chen, CT; Heslop, DC; Inam, A; Salahuddin, A; van Zyl, RL | 1 |
| Cooksey, R; Dahlström, S; Fairhurst, RM; Flegg, JA; Guerin, PJ; Johnson, JD; Le Bras, J; Le Nagard, H; Lim, P; Ménard, D; Mentré, F; Murillo, C; Musset, L; Noedl, H; Nosten, F; Nsobya, SL; Pradines, B; Quashie, NB; Sibley, CH; Sinou, V; Sriprawat, K; Woodrow, CJ | 1 |
| Baruah, I; Dhiman, S; Goswami, D; Rabha, B; Sharma, DK; Singh, L; Veer, V | 1 |
| Costa, FT; Cravo, P; Frausin, G; Freitas-Junior, LH; Lacerda, MV; Lima, RB; Lopes, SC; Moraes, CB; Pohlit, AM; Silva, LF; Siqueira, AM | 1 |
| Jegajeevanram, K; Karunamoorthi, K; Sabesan, S; Vijayalakshmi, J | 1 |
| Dondorp, AM; Faiz, MA; Hien, TT; Mokuolu, OA; Pukrittayakamee, S; White, NJ | 1 |
| Abdi, AI; Kiara, SM; Mwai, L; Nzila, A; Ochola-Oyier, LI; Okombo, J; Pole, L; Sutherland, CJ | 1 |
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| Chaijaroenkul, W; Muhamad, P; Na-Bangchang, K; Phompradit, P; Wisedpanichkij, R | 1 |
| Aldebert, D; Barale, JC; Jambou, R; Razakandrainibe, R; Varela, ML | 1 |
| Bala, N; Betuela, I; Davis, TM; Hetzel, MW; Lavu, EK; Page-Sharp, M; Pulford, J | 1 |
| Adner, M; Al-Ameri, M; Bergman, P; Dahlén, SE; James, A; Manson, ML; Orre, AC; Säfholm, J; Swärd, K | 1 |
| Arboleda, M; Blair, S; Fernández, D; Garavito, G; Pabón, A; Segura, C | 1 |
| Baret, E; Bercion, R; Camara, C; Diatta, B; Diémé, Y; Fall, B; Fall, KB; Fall, M; Mbaye, PS; Nakoulima, A; Pascual, A; Pradines, B; Wade, B; Wurtz, N | 1 |
| Bellanca, S; Dave, A; Dittmer, M; Lanzer, M; Martin, RE; Meyrath, M; Nash, MN; Sanchez, CP; Stein, WD; Summers, RL | 1 |
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61 review(s) available for chloroquine and quinine
| Article | Year |
|---|---|
Antimalarial activity: the search for marine-derived natural products with selective antimalarial activity.
Topics: Animals; Antimalarials; Magnetic Resonance Spectroscopy; Marine Toxins; Plants; Plasmodium; Porifera; Rhodophyta; Structure-Activity Relationship | 1996 |
Quinoline drug-heme interactions and implications for antimalarial cytostatic versus cytocidal activities.
Topics: Antimalarials; Crystallization; Drug Resistance; Heme; Hemeproteins; Humans; Malaria, Falciparum; Molecular Structure; Plasmodium falciparum; Quinolines | 2013 |
Quinoline-based antimalarial hybrid compounds.
Topics: Animals; Antimalarials; Drug Discovery; Humans; Malaria; Plasmodium; Quinolines | 2015 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Quinoline hybrids and their antiplasmodial and antimalarial activities.
Topics: Antimalarials; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines | 2017 |
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines | 2020 |
[Current information on treatment and prophylaxis of malaria (author's transl)].
Topics: Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Dose-Response Relationship, Drug; Female; Humans; Infant; Insect Repellents; Malaria; Male; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Pregnancy; Pyrimethamine; Quinine; Sulfadiazine; Sulfadoxine; Tetracycline | 1979 |
The treatment of severe falciparum malaria.
Topics: Adult; Antimalarials; Chloroquine; Erythrocytes; Humans; Infusions, Parenteral; Malaria; Male; Plasmodium falciparum; Quinine | 1977 |
The treatment of malaria.
Topics: Anemia; Antimalarials; Blackwater Fever; Child; Child, Preschool; Chloroquine; Coma; Drug Combinations; Drug Resistance, Microbial; Hemorrhage; Humans; Kidney Failure, Chronic; Malaria; Piperidines; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pulmonary Edema; Quinine; Quinolines; Sulfadoxine | 1976 |
Cerebral Malaria.
Topics: Adolescent; Adult; Antimalarials; Brain Diseases; Capillaries; Cerebral Cortex; Cerebral Hemorrhage; Child; Child, Preschool; Chloroquine; Diagnosis, Differential; Drug Administration Schedule; Female; Humans; Immunoglobulin G; Infant; Intracranial Embolism and Thrombosis; Kidney Diseases; Malaria; Male; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Cardiovascular; Quinine | 1975 |
Therapeutics review: the use of parenteral drugs for falciparum malaria.
Topics: Animals; Chloroquine; Drug Resistance, Microbial; Humans; Infusions, Intravenous; Injections, Intramuscular; Injections, Subcutaneous; Malaria; Plasmodium falciparum; Quinine | 1990 |
Treatment of severe malaria.
Topics: Animals; Antimalarials; Chloroquine; Critical Care; Drug Resistance; Female; Humans; Malaria; Plasmodium falciparum; Pregnancy; Quinine | 1989 |
Extension of multiple drug resistant Plasmodium falciparum malaria in Africa: report of a Central African case.
Topics: Adult; Animals; Chloroquine; Drug Resistance; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfanilamides | 1989 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
Pharmacokinetics of antimalarial drugs: their therapeutic and toxicological implications.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Half-Life; Humans; Kinetics; Male; Mefloquine; Mice; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine; Sulfalene | 1985 |
Recent advances in antimalarial chemotherapy and drug resistance.
Topics: Agglutination; Amodiaquine; Animals; Anti-Bacterial Agents; Antimalarials; Chloroquine; Cross Reactions; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Haplorhini; Humans; Lincomycin; Malaria; Pigments, Biological; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Quinacrine; Quinine; Quinolines; Structure-Activity Relationship; Sulfonamides; Sulfones | 1974 |
The present status of chloroquine in the drug treatment of malaria.
Topics: Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfonamides; Sulfones; Triazines | 1972 |
The problem of drug-resistant malaria.
Topics: Amodiaquine; Anopheles; Antimalarials; Asia; Chloroquine; Drug Resistance, Microbial; Humans; Insect Vectors; Malaria; Mutation; Plasmodium falciparum; Primaquine; Proguanil; Quinine; South America; Sulfonamides; Sulfones; Tetracycline; Virulence | 1972 |
A review of the drug sensitivity of Plasmodium falciparum in Thailand.
Topics: Chloroquine; Drug Resistance; Geography; Humans; Malaria; Methylamines; Naphthacenes; Plasmodium falciparum; Pyrazines; Pyrimethamine; Pyrimidines; Quinine; Sulfamethoxazole; Sulfonamides; Tetracycline; Thailand; Trimethoprim | 1972 |
Antimalarial drugs and their actions.
Topics: Antimalarials; Chloroquine; Drug Compounding; Drug Resistance, Microbial; Humans; Malaria; Plasmodium; Quinine; Sulfonamides | 1973 |
[Toxic effect of synthetic antimalarial drugs].
Topics: Accommodation, Ocular; Antimalarials; Chloroquine; Diplopia; Eye Diseases; Humans; Quinine; Retinal Pigments; Retinal Vessels | 1969 |
Chemotherapy of the drug-resistant malarias.
Topics: Chloroquine; Cinchona; Drug Resistance, Microbial; Malaria; Mutation; Phytotherapy; Plants, Medicinal; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Quinolines; Sulfonamides; Sulfones | 1969 |
Malaria treatment and prevention. A review.
Topics: Adolescent; Adult; Africa, Eastern; Antimalarials; Biguanides; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Humans; Infant; Infant Mortality; Infant, Newborn; Malaria; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Quinacrine; Quinine; Quinolines; Sulfonamides | 1969 |
Malaria. Chemoprophylaxis and chemotherapy.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Drug Synergism; Humans; Malaria; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Pyrimidines; Quinine; Sulfonamides; Triazines | 1971 |
Resistance of Plasmodium falciparum.
Topics: Africa; Animals; Antimalarials; Asia; Chloroquine; DNA; Drug Resistance; Drug Synergism; Hemin; Malaria; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Quinolines; Research; RNA; South America | 1984 |
[Progress in immunodiagnosis and chemotherapy of protozoan infections].
Topics: Amebiasis; Animals; Antibodies; Babesiosis; Chloroquine; Drug Resistance, Microbial; Giardiasis; Humans; Leishmaniasis; Malaria; Mefloquine; Pneumocystis; Pneumonia, Pneumocystis; Primaquine; Protozoan Infections; Pyrimethamine; Quinine; Quinolines; Serologic Tests; Sulfadoxine; Tetracycline; Toxoplasmosis; Trypanosomiasis | 1983 |
[Drug resistance in malaria].
Topics: Africa; Amodiaquine; Animals; Asia; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; South America; Sulfanilamides | 1980 |
Antimalarial drug resistance: an increasing problem.
Topics: Aminoquinolines; Animals; Antimalarials; Aotus trivirgatus; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Mice; Microbial Sensitivity Tests; Plasmodium; Plasmodium falciparum; Plasmodium vivax; Primaquine; Quinine; Triazines | 1982 |
[Current malaria management in Switzerland].
Topics: Adult; Animals; Antimalarials; Chloroquine; Critical Care; Drug Resistance; Female; Humans; Malaria; Malaria, Falciparum; Male; Plasmodium; Quinine; Switzerland | 1994 |
Clinical pharmacokinetics in the treatment of tropical diseases. Some applications and limitations.
Topics: Chloroquine; Diethylcarbamazine; Drug Resistance; Echinococcosis; Filariasis; Humans; Malaria; Mefloquine; Pharmacokinetics; Phenanthrenes; Pyrimethamine; Quinine; Sulfadoxine; Tropical Medicine | 1994 |
[Research for new antimalarial molecules: an emergency, a hope].
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Emergency Medicine; Humans; In Vitro Techniques; Phospholipids; Plasmodium falciparum; Quinine | 1994 |
[Malaria: the most important emergency in subjects returning from the tropics].
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Emergencies; Humans; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium; Pyrimethamine; Quinidine; Quinine; Sulfadoxine | 1993 |
Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Interactions; Drug Therapy, Combination; Malaria, Falciparum; Molecular Conformation; Quinidine; Quinine | 1996 |
Quinoline antimalarials: mechanisms of action and resistance.
Topics: Animals; Antimalarials; Blood Proteins; Chloroquine; Drug Resistance; Erythrocytes; Hemoglobins; Humans; Mefloquine; Membrane Proteins; Plasmodium; Quinine; Quinolines | 1997 |
[Neurological toxicity of antifungal and antiprotozoal drugs].
Topics: Amphotericin B; Antifungal Agents; Antimalarials; Antiprotozoal Agents; Antitrichomonal Agents; Central Nervous System Diseases; Chloroquine; Humans; Mefloquine; Metronidazole; Quinine | 1999 |
In vitro activities of strychnos alkaloids and extracts against Plasmodium falciparum.
Topics: Alkaloids; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Plasmodium falciparum; Quinine; Structure-Activity Relationship | 1999 |
Comparative efficacy and safety of chloroquine and alternative antimalarial drugs: a meta-analysis from six African countries.
Topics: Africa, Eastern; Africa, Western; Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Costs; Humans; Malaria; Mefloquine; Patient Selection; Phenanthrenes; Pyrimethamine; Quinine; Safety; Sulfadoxine; Treatment Outcome | 1999 |
Clindamycin as an antimalarial drug: review of clinical trials.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Chloroquine; Clindamycin; Drug Combinations; Female; Humans; Malaria; Plasmodium vivax; Pregnancy; Quinine | 2002 |
Chemotherapeutic agents against malaria: what next after chloroquine?
Topics: Animals; Antimalarials; Artemisinins; Biological Factors; Chloroquine; Folic Acid Antagonists; Humans; Malaria; Protease Inhibitors; Quinine; Sesquiterpenes | 2002 |
[EXTRAMALARIAL THERAPUETIC APPLICATIONS OF ANTIMALARIAL DRUGS. 1. CLINICAL UTILIZATIONS].
Topics: Amodiaquine; Antimalarials; Chloroquine; Collagen Diseases; Dermatology; Drug Utilization; Epilepsy; Female; Heart Diseases; Hematology; Humans; Hydroxychloroquine; Hypersensitivity; Multiple Sclerosis; Muscular Diseases; Neurology; Parasitic Diseases; Pharmacology; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Toxicology; Uterus | 1963 |
THE PENDULUM IN MALARIA CHEMOTHERAPY: FROM QUININE TO CHLOROQUINE AND BACK TO QUININE?
Topics: Antimalarials; Biomedical Research; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Humans; Malaria; Military Medicine; Quinine; Tropical Medicine | 1964 |
Management of severe malaria.
Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Combined Modality Therapy; Developing Countries; Endemic Diseases; Exchange Transfusion, Whole Blood; Female; Humans; Incidence; India; Infant; Malaria, Falciparum; Male; Quinine; Randomized Controlled Trials as Topic; Risk Assessment; Sesquiterpenes; Severity of Illness Index; Sex Distribution | 2004 |
QTL analysis for discovery of genes involved in drug responses.
Topics: Alleles; Animals; Biological Evolution; Chloroquine; Chromosome Mapping; Drug Design; Drug Resistance; Drug Resistance, Multiple; Gene Expression; Genes; Genome, Protozoan; Genomics; Humans; Malaria, Falciparum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Quinine | 2004 |
Emerging drug--resistance and guidelines for treatment of malaria.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Pakistan; Phenanthrenes; Plasmodium falciparum; Quinidine; Quinine; Sesquiterpenes; Time Factors | 2004 |
[Combined antimalarial therapy using artemisinin].
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2004 |
Malaria in endemic areas.
Topics: Antimalarials; Artemether; Artemisinins; Blood Transfusion; Chloroquine; Deferoxamine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
Effectiveness of antimalarial drugs.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Life Cycle Stages; Malaria; Mefloquine; Patient Compliance; Plasmodium; Primaquine; Pyrimethamine; Quinine; Secondary Prevention; Sulfadoxine; Treatment Failure | 2005 |
Antimalarial drugs: recent advances in molecular determinants of resistance and their clinical significance.
Topics: Africa; Amino Alcohols; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Biological Transport; Calcium-Transporting ATPases; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Gene Amplification; Humans; Malaria, Falciparum; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Models, Biological; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinine; Sesquiterpenes | 2006 |
Current malaria status and distribution of drug resistance in East and Southeast Asia with special focus to Thailand.
Topics: Age Factors; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium; Quinine; Sesquiterpenes; Sex Factors; Sulfadoxine | 2007 |
Pharmacokinetics of antimalarials in pregnancy: a systematic review.
Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Sulfadoxine | 2011 |
Primaquine for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2012 |
Chemotherapy and drug resistance status of malaria parasite in northeast India.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; India; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Quinine | 2013 |
Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads.
Topics: Antimalarials; Artemisia annua; Biological Products; Chloroquine; Drug Discovery; Humans; Malaria; Plasmodium falciparum; Quinine | 2013 |
Role of traditional antimalarial plants in the battle against the global malaria burden.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Global Health; Humans; Malaria; Medicine, Traditional; Plant Components, Aerial; Plant Roots; Plants, Medicinal; Plasmodium; Quinine | 2013 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine | 2014 |
Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2014 |
Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2015 |
Primaquine or other 8-aminoquinolines for reducing Plasmodium falciparum transmission.
Topics: Adult; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Non-Randomized Controlled Trials as Topic; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine; Time Factors | 2018 |
Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup.
Topics: Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Female; Humans; Hydroxychloroquine; Male; Outcome Assessment, Health Care; Pandemics; Pneumonia, Viral; Poisoning; Practice Guidelines as Topic; Quinine; Renal Dialysis; Risk Assessment; United States | 2020 |
[History of aminoquinoline preparations: from cinchona bark to chloroquine and hydroxychloroquinon].
Topics: Antimalarials; Chloroquine; Cinchona; Plant Bark; Quinine | 2020 |
Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines.
Topics: Adult; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Chloroquine; Drug Combinations; Female; Humans; Malaria; Parasitemia; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinine; Sulfadoxine | 2021 |
36 trial(s) available for chloroquine and quinine
| Article | Year |
|---|---|
In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda.
Topics: Antimalarials; Child; Child, Preschool; Cohort Studies; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Treatment Outcome; Uganda | 2010 |
Chloroquine-resistant malaria in Burma.
Topics: Chloroquine; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Myanmar; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfamethoxypyridazine; Trimethoprim | 1975 |
A comparative study on the use of intramuscular chloroquine and quinine (as Quinimax) in the treatment of uncomplicated falciparum malaria in adults.
Topics: Adult; Chloroquine; Female; Humans; Injections, Intramuscular; Malaria; Male; Quinine | 1979 |
Parasitological, clinical and haematological response of children with Plasmodium falciparum to 4-aminoquinolines and to pyrimethamine-sulfadoxine with quinine in western Kenya.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Erythrocyte Count; Female; Hematocrit; Hemoglobins; Hospitals; Humans; Infant; Kenya; Malaria, Falciparum; Male; Pyrimethamine; Quinine; Reticulocytes; Seroepidemiologic Studies; Sulfadoxine | 1992 |
Evaluation of the relative efficacy of various antimalarial drugs in Nigerian children under five years of age suffering from acute uncomplicated falciparum malaria.
Topics: Acute Disease; Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Mefloquine; Nigeria; Pyrimethamine; Quinine; Sulfadoxine | 1992 |
Efficacy of quinine for falciparum malaria according to previous chloroquine exposure.
Topics: Animals; Child; Child, Preschool; Chloroquine; Coma; Drug Evaluation; Drug Resistance; Female; Humans; Infant; Malaria; Malawi; Male; Plasmodium falciparum; Quinine | 1991 |
Open comparison of intramuscular chloroquine and quinine in children with severe chloroquine-sensitive falciparum malaria.
Topics: Administration, Oral; Animals; Child; Child, Preschool; Chloroquine; Female; Gambia; Humans; Infant; Injections, Intramuscular; Malaria; Male; Plasmodium falciparum; Quinine; Random Allocation | 1989 |
Chloroquine and quinine: a randomized, double-blind comparison of efficacy and side effects in the treatment of Plasmodium falciparum malaria in the Philippines.
Topics: Adolescent; Adult; Animals; Chloroquine; Clinical Trials as Topic; Double-Blind Method; Humans; Malaria; Male; Middle Aged; Philippines; Plasmodium falciparum; Quinine; Random Allocation | 1988 |
Evaluation of the sensitivity in vivo and in vitro of Plasmodium falciparum malaria to quinine in an area of full sensitivity to chloroquine.
Topics: Animals; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Resistance; Female; Humans; Infant; Malaria; Male; Nigeria; Plasmodium falciparum; Quinine | 1988 |
Parasitologic and clinical efficacy of 25 and 50 mg/kg of chloroquine for treatment of Plasmodium falciparum malaria in Rwandan children.
Topics: Animals; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Infant; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Rwanda | 1988 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
The influence of ovarian hormones and of pregnancy on the action of some antimalarials on the isolated spontaneously contracting rat uterus.
Topics: Antimalarials; Chloroquine; Clinical Trials as Topic; Drug Interactions; Estradiol; Female; Histamine H1 Antagonists; Hormones; Humans; Ovary; Progesterone; Proguanil; Quinacrine; Quinine; Uterus | 1971 |
Tetracycline treatment of chloroquine-resistant falciparum malaria in Thailand.
Topics: Administration, Oral; Chloroquine; Drug Resistance, Microbial; Drug Synergism; Humans; Malaria; Plasmodium falciparum; Quinine; Tetracycline; Thailand; Time Factors | 1972 |
The drug response of a normal and a multi-resistant strain of P. falciparum to sulphalene.
Topics: Chloroquine; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Synergism; Folic Acid Antagonists; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Quinine; Sulfonamides | 1968 |
Characterization of a drug resistant strain of Plasmodium falciparum from the Philippines.
Topics: Adult; Anopheles; Chloroquine; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Malaria; Male; Philippines; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine | 1971 |
Prophylactic and sporontocidal treatment of chloroquine-resistant Plasmodium falciparum from Vietnam.
Topics: Adult; Antimalarials; Chloroquine; Clinical Trials as Topic; Dapsone; Humans; Malaria; Male; Methemoglobin; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine; Sulfonamides; United States; Vietnam | 1971 |
Clinical studies with a drug-resistant strain of Plasmodium falciparum from Vietnam.
Topics: Adult; Chloroquine; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Vietnam | 1966 |
Characteristics of four new drug-resistant strains of Plasmodium falciparum from South-East Asia.
Topics: Adult; Antimalarials; Asia, Southeastern; Chloroquine; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine | 1969 |
In vivo and in vitro sensitivity of Falciparum malaria to quinine in Thai children.
Topics: Child; Child, Preschool; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Female; Humans; Infant; Malaria; Male; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Random Allocation; Thailand | 1981 |
Efficacy and tolerance in adults of a short (3 days) course of quinine for uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Cameroon; Chloroquine; Drug Tolerance; Female; Humans; Malaria, Falciparum; Male; Quinine | 1995 |
Clindamycin in combination with chloroquine or quinine is an effective therapy for uncomplicated Plasmodium falciparum malaria in children from Gabon.
Topics: Adolescent; Child; Child, Preschool; Chloroquine; Clindamycin; Drug Therapy, Combination; Female; Gabon; Humans; Malaria, Falciparum; Male; Quinine | 1994 |
Resistance of Plasmodium falciparum to antimalarial drugs in Equatorial Guinea.
Topics: Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Equatorial Guinea; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1993 |
Therapeutic effects of chloroquine in combination with quinine in uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antimalarials; Chloroquine; Drug Therapy, Combination; Fever; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Parasitemia; Quinine; Recurrence; Tetracycline; Thailand; Treatment Outcome | 1996 |
A comparative study of parenteral chloroquine, quinine and pyrimethamine-sulfadoxine in the treatment of Gambian children with complicated, non-cerebral malaria.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Data Interpretation, Statistical; Drug Combinations; Drug Resistance; Gambia; Humans; Infant; Infusions, Parenteral; Malaria, Falciparum; Pyrimethamine; Quinine; Sulfadoxine; Time Factors | 1996 |
Response of uncomplicated falciparum malaria to oral chloroquine and quinine in Burundi highlands.
Topics: Administration, Oral; Adolescent; Age Factors; Antimalarials; Burundi; Child; Child, Preschool; Chloroquine; Humans; Infant; Malaria, Falciparum; Quinine; Treatment Outcome | 1998 |
In vivo-in vitro model for the assessment of clinically relevant antimalarial cross-resistance.
Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Models, Biological; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Recurrence; Sesquiterpenes | 2001 |
In vivo drug resistance of falciparum malaria in mining areas of Venezuela.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Health Promotion; Humans; Malaria, Falciparum; Male; Mining; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Treatment Failure; Treatment Outcome; Venezuela | 2002 |
Artemether bioavailability after oral or intramuscular administration in uncomplicated falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Area Under Curve; Artemether; Artemisinins; Biological Assay; Biological Availability; Biotransformation; Chloroquine; Drug Resistance; Female; Humans; Injections, Intramuscular; Intestinal Absorption; Malaria, Falciparum; Male; Middle Aged; Quinine; Sesquiterpenes | 2003 |
Low-dose quinine is effective in the treatment of chloroquine-resistant Plasmodium falciparum malaria in eastern Sudan.
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Resistance; Humans; Infant; Malaria, Falciparum; Middle Aged; Parasitemia; Quinine; Recurrence | 2004 |
A prospective study evaluating the efficacy of a single, 45-mg dose of primaquine, as a gametocytocidal agent, in patients with Plasmodium falciparum malaria in Mumbai, India.
Topics: Adolescent; Adult; Aged; Antimalarials; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Primaquine; Prospective Studies; Quinine | 2004 |
Efficacies of chloroquine, sulfadoxine-pyrimethamine and quinine in the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Humans; Infant; Malaria, Falciparum; Pyrimethamine; Quinine; Sudan; Sulfadoxine; Treatment Failure; Treatment Outcome | 2004 |
Quinine for the treatment of chloroquine-resistant Plasmodium falciparum malaria in pregnant and non-pregnant Sudanese women.
Topics: Adult; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Quinine; Treatment Outcome | 2005 |
Clinical-parasitological response and in-vitro sensitivity of Plasmodium vivax to chloroquine and quinine on the western border of Thailand.
Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Drug Resistance; Female; Humans; Malaria, Vivax; Male; Middle Aged; Myanmar; Parasitic Sensitivity Tests; Plasmodium vivax; Quinine; Thailand | 2006 |
Thymus size at 6 months of age and subsequent child mortality.
Topics: BCG Vaccine; Child; Child Mortality; Chloroquine; Cohort Studies; Female; Humans; Infant; Male; Measles Vaccine; Quinine; Risk Factors; Thymus Extracts; Thymus Gland; Ultrasonography | 2008 |
A controlled trial to assess the effect of quinine, chloroquine, amodiaquine, and artesunate on Loa loa microfilaremia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amodiaquine; Animals; Anthelmintics; Artemisinins; Artesunate; Chloroquine; Humans; Loa; Loiasis; Middle Aged; Quinine; Young Adult | 2010 |
Temporal and seasonal changes of genetic polymorphisms associated with altered drug susceptibility to chloroquine, lumefantrine, and quinine in Guinea-Bissau between 2003 and 2012.
Topics: Adolescent; Antimalarials; Child; Child, Preschool; Chloroquine; Ethanolamines; Female; Fluorenes; Guinea-Bissau; Humans; Lumefantrine; Malaria, Falciparum; Male; Quinine | 2015 |
698 other study(ies) available for chloroquine and quinine
| Article | Year |
|---|---|
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Acid Antagonists; Malaria; Mice; Plasmodium berghei; Triazines | 1977 |
Antimalarial activity of sesquiterpenes from the marine sponge Acanthella klethra.
Topics: Animals; Antimalarials; Cell Survival; Humans; KB Cells; Plasmodium falciparum; Porifera; Sesquiterpenes | 1992 |
Antimalarial activity of new water-soluble dihydroartemisinin derivatives. 2. Stereospecificity of the ether side chain.
Topics: Animals; Artemisinins; Chemical Phenomena; Chemistry; Malaria; Mice; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Solubility; Stereoisomerism; Structure-Activity Relationship; Water | 1989 |
Thalifaberidine, a cytotoxic aporphine-benzylisoquinoline alkaloid from Thalictrum faberi.
Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Aporphines; Drugs, Chinese Herbal; HIV; Humans; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Mice; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured | 1994 |
Synthesis and in vitro evaluation of 9-anilino-3,6-diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum.
Topics: Aminoacridines; Animals; Antimalarials; Cell Division; Cells, Cultured; Drug Resistance; Erythrocytes; Humans; Plasmodium falciparum; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1994 |
Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Phenanthridines; Plants, Medicinal; Plasmodium falciparum; Spectrophotometry, Ultraviolet | 1993 |
Cytotoxic and antimalarial alkaloids from the tubers of Stephania pierrei.
Topics: Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Aporphines; Drug Screening Assays, Antitumor; Glucosides; Isoquinolines; Magnetic Resonance Spectroscopy; Molecular Weight; Plants, Medicinal; Plasmodium falciparum; Species Specificity | 1993 |
A new antimalarial quassinoid from Simaba guianensis.
Topics: Animals; Antimalarials; Brazil; Bridged Bicyclo Compounds; Chromatography, Thin Layer; Glaucarubin; Magnetic Resonance Spectroscopy; Plant Extracts; Plants, Medicinal; Plasmodium falciparum; Quassins; Spectrophotometry, Ultraviolet | 1993 |
Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Stephania erecta.
Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Cell Survival; Drug Screening Assays, Antitumor; Erythrocytes; Female; Humans; In Vitro Techniques; Male; Mice; Plants, Medicinal; Plasmodium falciparum; Thailand; Tumor Cells, Cultured | 1993 |
Costaricine, a new antiplasmodial bisbenzylisoquinoline alkaloid from Nectandra salicifolia trunk bark.
Topics: Alkaloids; Animals; Antimalarials; Chromatography, Thin Layer; Costa Rica; Mass Spectrometry; Plants, Medicinal; Plasmodium falciparum | 1996 |
Antimalarial activity of tropical Meliaceae extracts and gedunin derivatives.
Topics: Animals; Antimalarials; Cell Survival; Chloroquine; Drug Resistance; Humans; KB Cells; Limonins; Malaria, Falciparum; Mice; Plant Extracts; Plants, Medicinal; Plasmodium falciparum; Rats; Secosteroids; Structure-Activity Relationship | 1997 |
In vitro and in vivo antiplasmodial activity of cryptolepine and related alkaloids from Cryptolepis sanguinolenta.
Topics: Alkaloids; Animals; Antimalarials; Humans; In Vitro Techniques; Indole Alkaloids; Indoles; Mice; Microbial Sensitivity Tests; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Quinolines; Spectrum Analysis | 1997 |
Enhancement of NO production in activated macrophages in vivo by an antimalarial crude drug, Dichroa febrifuga.
Topics: Animals; Antimalarials; China; In Vitro Techniques; Macrophages; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Nitric Oxide; Piperidines; Plant Extracts; Plant Roots; Plants, Medicinal; Quinazolines; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1998 |
Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids.
Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Strychnogucines A and B, two new antiplasmodial bisindole alkaloids from Strychnos icaja.
Topics: Alkaloids; Animals; Antimalarials; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plasmodium falciparum; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Strychnine | 2001 |
Structure-activity relationships of novel anti-malarial agents. Part 2: cinnamic acid derivatives.
Topics: Animals; Antimalarials; Cinnamates; Combinatorial Chemistry Techniques; Inhibitory Concentration 50; Microbial Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2001 |
Antimalarial compounds from Rhaphidophora decursiva.
Topics: Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Leaves; Plant Stems; Plants, Medicinal; Plasmodium falciparum; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured; Vietnam | 2001 |
Synthesis of new artemisinin analogues from artemisinic acid modified at C-3 and C-13 and their antimalarial activity.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Chromatography, Thin Layer; Drug Resistance, Microbial; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; KB Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Structure-Activity Relationship | 2001 |
Structure-activity relationships of novel anti-malarial agents. Part 3: N-(4-acylamino-3-benzoylphenyl)-4-propoxycinnamic acid amides.
Topics: Amides; Animals; Antimalarials; Benzophenones; Cinnamates; Humans; Inhibitory Concentration 50; Phenylacetates; Plasmodium falciparum; Structure-Activity Relationship | 2002 |
Rhodacyanine dyes as antimalarials. 1. Preliminary evaluation of their activity and toxicity.
Topics: Animals; Antimalarials; Coloring Agents; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Thiazoles | 2002 |
Synthesis and evaluation of new antimalarial analogues of quinoline alkaloids derived from Cinchona ledgeriana Moens ex Trimen.
Topics: Animals; Antimalarials; Chloroquine; Cinchona Alkaloids; Drug Design; Drug Resistance; Erythrocytes; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Plasmodium; Quinolines; Structure-Activity Relationship | 2002 |
Antimalarial compounds from Parinari capensis.
Topics: Animals; Antimalarials; Cell Line; Diterpenes; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Kidney; Lactones; Molecular Structure; Plant Extracts; Plant Stems; Plasmodium falciparum; Rosales | 2002 |
Structure-activity relationships of the antimalarial agent artemisinin. 7. Direct modification of (+)-artemisinin and in vivo antimalarial screening of new, potential preclinical antimalarial candidates.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Drug Evaluation, Preclinical; Drug Resistance; Injections, Intravenous; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 2002 |
Structure-activity relationships of novel anti-malarial agents. Part 4: N-(3-benzoyl-4-tolylacetylaminophenyl)-3-(5-aryl-2-furyl)acrylic acid amides.
Topics: Acrylamides; Animals; Antimalarials; Drug Resistance; Hydrogen Bonding; Indicators and Reagents; Plasmodium falciparum; Structure-Activity Relationship | 2002 |
Antiplasmodial activity of alkaloids from various strychnos species.
Topics: Alkaloids; Animals; Antimalarials; Drug Evaluation, Preclinical; Plasmodium falciparum; Structure-Activity Relationship; Strychnos | 2002 |
Structure-activity relationships of novel anti-malarial agents. Part 7: N-(3-benzoyl-4-tolylacetylaminophenyl)-3-(5-aryl-2-furyl)acrylic acid amides with polar moieties.
Topics: Acrylates; Alkyl and Aryl Transferases; Amides; Animals; Antimalarials; Enzyme Inhibitors; Farnesyltranstransferase; Furans; Hydrogen Bonding; Indicators and Reagents; Plasmodium falciparum; Structure-Activity Relationship | 2003 |
The imidazo[2,1-a]isoindole system. A new skeletal basis for antiplasmodial compounds.
Topics: Animals; Antimalarials; Chloroquine; Imidazoles; Indoles; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2003 |
Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry.
Topics: Animals; Apamin; Guinea Pigs; Hepatocytes; Kinetics; Molecular Conformation; Potassium Channels, Calcium-Activated | 2004 |
Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound.
Topics: Alkaloids; Animals; Antimalarials; Apocynaceae; Indole Alkaloids; Indoles; Molecular Structure; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2005 |
Lupeol long-chain fatty acid esters with antimalarial activity from Holarrhena floribunda.
Topics: Animals; Antimalarials; Cameroon; Erythrocytes; Fatty Acids; Holarrhena; Molecular Structure; Pentacyclic Triterpenes; Plant Bark; Plants, Medicinal; Plasmodium falciparum; Structure-Activity Relationship; Triterpenes | 2006 |
Antimalarial effect of bis-pyridinium salts, N,N'-hexamethylenebis(4-carbamoyl-1-alkylpyridinium bromide).
Topics: Animals; Antimalarials; Cell Line, Tumor; Mice; Plasmodium falciparum; Pyridinium Compounds | 2006 |
Biological activities and 3D QSAR studies of a series of Delisea pulchra (cf. fimbriata) derived natural products.
Topics: Anti-Infective Agents; Antimalarials; Antineoplastic Agents; Antitubercular Agents; Furans; HIV Reverse Transcriptase; Hydrocarbons, Halogenated; Interleukin-1; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Kinase C; Protein-Tyrosine Kinases; Quantitative Structure-Activity Relationship; Rhodophyta | 2006 |
In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Azithromycin; Clinical Trials, Phase II as Topic; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes | 2007 |
High-throughput Plasmodium falciparum growth assay for malaria drug discovery.
Topics: Animals; Biological Assay; Child, Preschool; DNA, Protozoan; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Female; Humans; Indoles; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Pregnancy | 2007 |
Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening.
Topics: Animals; Antimalarials; Benzothiazoles; Diamines; Drug Evaluation, Preclinical; Erythrocytes; Fluorescent Dyes; Humans; Hypoxanthine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Reproducibility of Results; Sensitivity and Specificity | 2007 |
Synthesis and heme-binding correlation with antimalarial activity of 3,6-bis-(omega-N,N-diethylaminoamyloxy)-4,5-difluoroxanthone.
Topics: Animals; Antimalarials; Fluorine; Heme; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Spectrophotometry; Structure-Activity Relationship; Xanthones | 2008 |
Differential effects of quinoline antimalarials on endocytosis in Plasmodium falciparum.
Topics: Amodiaquine; Animals; Antimalarials; Blotting, Western; Chloroquine; Endocytosis; Erythrocytes; Hemoglobins; Humans; Mefloquine; Peroxidase; Phenanthrenes; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Quinolines | 2008 |
Pharmacophore based discovery of potential antimalarial agent targeting haem detoxification pathway.
Topics: Animals; Antimalarials; Drug Discovery; Heme; Isoniazid; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Small Molecule Libraries; Stereoisomerism | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytes.
Topics: Animals; Antimalarials; Biological Transport, Active; Cell Membrane Permeability; Cysteine Proteinase Inhibitors; Drug Resistance; Erythrocytes; Genes, Protozoan; Humans; In Vitro Techniques; Ion Channels; Leupeptins; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Carbonic anhydrase inhibitors: inhibition of Plasmodium falciparum carbonic anhydrase with aromatic/heterocyclic sulfonamides-in vitro and in vivo studies.
Topics: Animals; Antimalarials; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chemistry, Pharmaceutical; Drug Design; Humans; Inhibitory Concentration 50; Kinetics; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Pyrimidines; Sulfonamides | 2008 |
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Benzylamines; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Female; Haplorhini; Heme; Humans; Malaria; Mice; Models, Molecular; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Structure-Activity Relationship | 2009 |
Dynamics of malaria drug resistance patterns in the Amazon basin region following changes in Peruvian national treatment policy for uncomplicated malaria.
Topics: Animals; Antimalarials; Drug Resistance; Genotype; Haplotypes; Health Policy; Humans; Malaria, Falciparum; Microsatellite Repeats; Mutation; Parasitic Sensitivity Tests; Peru; Plasmodium falciparum; Protozoan Proteins | 2009 |
Antiproliferative and antimalarial anthraquinones of Scutia myrtina from the Madagascar forest.
Topics: Animals; Anthraquinones; Antimalarials; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Madagascar; Plant Bark; Plant Extracts; Plasmodium falciparum; Rhamnaceae | 2009 |
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Cell Survival; Chloroquine; Dogs; Drug Resistance; Female; Haplorhini; Hepatocytes; Humans; In Vitro Techniques; Malaria; Male; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Rats, Wistar; Structure-Activity Relationship | 2009 |
Atorvastatin is a promising partner for antimalarial drugs in treatment of Plasmodium falciparum malaria.
Topics: Animals; Antimalarials; Atorvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Plasmodium falciparum; Pyrroles | 2009 |
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid.
Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Antimalarial activity of tigecycline, a novel glycylcycline antibiotic.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Doxycycline; Inhibitory Concentration 50; Minocycline; Parasitic Sensitivity Tests; Plasmodium falciparum; Tetracycline; Tetracyclines; Tigecycline | 2009 |
Plasmodium falciparum drug resistance in Madagascar: facing the spread of unusual pfdhfr and pfmdr-1 haplotypes and the decrease of dihydroartemisinin susceptibility.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Haplotypes; Madagascar; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Synthesis and antimalarial activity of new atovaquone derivatives.
Topics: Antimalarials; Atovaquone; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2009 |
Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.
Topics: Aminoquinolines; Antimalarials; Ciprofloxacin; Ferrous Compounds; Metallocenes; Plasmodium falciparum; Prodrugs | 2009 |
Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections.
Topics: Animals; Anti-Infective Agents; Carbazoles; Cerebellar Diseases; Indole Alkaloids; Mice; Microbial Sensitivity Tests; Molecular Structure; Neurogenic Inflammation; Porifera; Stereoisomerism; Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA.
Topics: Aminoquinolines; Antimalarials; Antineoplastic Agents; Cell Line, Tumor; DNA; Drug Resistance; Drug Screening Assays, Antitumor; Hemeproteins; Humans; Mannich Bases; Plasmodium falciparum; Structure-Activity Relationship | 2010 |
In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya.
Topics: Amino Acid Sequence; Animals; Antimalarials; Drug Resistance; Humans; Kenya; Mefloquine; Membrane Transport Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Sequence Analysis, DNA; Sodium-Hydrogen Exchangers | 2010 |
Absence of association between piperaquine in vitro responses and polymorphisms in the pfcrt, pfmdr1, pfmrp, and pfnhe genes in Plasmodium falciparum.
Topics: Animals; Antimalarials; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania major.
Topics: Adenosine Triphosphate; Aminoquinolines; Antiprotozoal Agents; Drug Resistance; Glycolysis; Leishmania major; Pyruvate Kinase | 2011 |
Antiprotozoal activity of chloroquinoline based chalcones.
Topics: Antiprotozoal Agents; Cell Line, Tumor; Cell Proliferation; Chalcones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Entamoeba histolytica; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Stereoisomerism; Structure-Activity Relationship | 2011 |
2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.
Topics: Aminoquinolines; Animals; Antimalarials; Cell Line; DNA; Dogs; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Plasmodium falciparum; Protoporphyrins; Pyrimidines; Structure-Activity Relationship; Viruses | 2012 |
Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum.
Topics: Antimalarials; Chloroquine; Cinchona Alkaloids; Drug Resistance; Inhibitory Concentration 50; Molecular Structure; Plasmodium falciparum; Quinine | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Chikungunya virus: emerging targets and new opportunities for medicinal chemistry.
Topics: Alphavirus Infections; Chikungunya Fever; Chikungunya virus; Disease Outbreaks; Europe; Humans; Models, Molecular | 2014 |
Urea/oxalamide tethered β-lactam-7-chloroquinoline conjugates: synthesis and in vitro antimalarial evaluation.
Topics: Antimalarials; beta-Lactams; Chloroquine; Humans; Malaria, Falciparum; Oxamic Acid; Plasmodium falciparum; Structure-Activity Relationship; Urea | 2014 |
Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Bacteria; Dose-Response Relationship, Drug; Fungi; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymers; Pyrazoles; Quinolines; Structure-Activity Relationship | 2014 |
Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Bacteria; Dose-Response Relationship, Drug; Drug Design; Fungi; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrazoles; Structure-Activity Relationship | 2014 |
Synthesis of isocryptolepine analogues and their structure-activity relationship studies as antiplasmodial and antiproliferative agents.
Topics: Antimalarials; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Chemistry Techniques, Synthetic; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Indole Alkaloids; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2015 |
Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities.
Topics: Anti-Infective Agents; Antimalarials; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi; Humans; Malaria, Falciparum; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Mycoses; Plasmodium falciparum; Pyrazoles; Quinolines; Structure-Activity Relationship; Tuberculosis | 2016 |
Synthesis, identification and in vitro biological evaluation of some novel quinoline incorporated 1,3-thiazinan-4-one derivatives.
Topics: Anti-Bacterial Agents; Antimalarials; Antitubercular Agents; Clostridium tetani; Gram-Negative Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmodium falciparum; Quinolines; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thiazines | 2017 |
Synthesis, characterization, molecular docking and in vitro antimalarial properties of new carboxamides bearing sulphonamide.
Topics: Antimalarials; Dose-Response Relationship, Drug; Malaria; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Sulfonamides | 2017 |
Ionic liquid mediated stereoselective synthesis of alanine linked hybrid quinazoline-4(3H)-one derivatives perturbing the malarial reductase activity in folate pathway.
Topics: Alanine; Animals; Antimalarials; Caco-2 Cells; Catalysis; Chlorocebus aethiops; Dose-Response Relationship, Drug; Enzyme Inhibitors; Folic Acid; Humans; Ionic Liquids; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinazolinones; Stereoisomerism; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Vero Cells | 2017 |
Potent Antimalarial Activity of Two Arenes Linked with Triamine Designed To Have Multiple Interactions with Heme.
Topics: | 2018 |
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Topics: Acridones; Animals; Antimalarials; Disease Models, Animal; Drug Discovery; Hep G2 Cells; Humans; Malaria; Mice; Plasmodium; Species Specificity; Structure-Activity Relationship | 2019 |
Green synthesis, biological evaluation, molecular docking studies and 3D-QSAR analysis of novel phenylalanine linked quinazoline-4(3H)-one-sulphonamide hybrid entities distorting the malarial reductase activity in folate pathway.
Topics: Antimalarials; Humans; Malaria, Falciparum; Molecular Docking Simulation; Molecular Structure; Phenylalanine; Quantitative Structure-Activity Relationship; Sulfonamides | 2019 |
Structure based design, synthesis, and biological evaluation of imidazole derivatives targeting dihydropteroate synthase enzyme.
Topics: Anti-Bacterial Agents; Dihydropteroate Synthase; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Imidazoles; Ligands; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin-Resistant Enterococci | 2021 |
Design, synthesis and biological evaluation of mono- and bisquinoline methanamine derivatives as potential antiplasmodial agents.
Topics: Antimalarials; Dose-Response Relationship, Drug; Drug Design; Methylamines; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2021 |
Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors.
Topics: Antimalarials; Cell Survival; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimidines; Quinolines; Structure-Activity Relationship; Thermodynamics | 2021 |
Design, synthesis, and characterization of novel aminoalcohol quinolines with strong in vitro antimalarial activity.
Topics: Amino Alcohols; Animals; Antimalarials; Cell Line; Cricetulus; Dose-Response Relationship, Drug; Drug Design; Ether-A-Go-Go Potassium Channels; Female; Humans; Malaria; Mice; Mice, Inbred BALB C; Microsomes, Liver; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2022 |
[Use of cation exchange filter paper for the assaying of small amounts of quinine, aminophenazone, chloroquine, ajmaline, promazine and pernazine].
Topics: Ajmaline; Aminopyrine; Antipsychotic Agents; Cation Exchange Resins; Chloroquine; Ion Exchange Resins; Microchemistry; Perazine; Promazine; Quinine | 1977 |
Chloroquine, quinine, procaine, quinidine, tricyclic antidepressants, and methylxanthines as prostaglandin agonists and antagonists.
Topics: Antidepressive Agents, Tricyclic; Antimalarials; Chloroquine; Ductus Arteriosus, Patent; Humans; Infant; Procaine; Prostaglandin Antagonists; Quinidine; Quinine; Xanthines | 1976 |
Drug toxicity of the inner ear.
Topics: Animals; Chloroquine; Dihydrostreptomycin Sulfate; Ethacrynic Acid; Furosemide; Gentamicins; Humans; Kanamycin; Labyrinth Diseases; Neomycin; Quinine; Salicylates; Streptomycin; Tobramycin | 1979 |
Plasmodium falciparum and Plasmodium vivax infections in the owl monkey (Aotus trivirgatus). II. Responses to chloroquine, quinine, and pyrimethamine.
Topics: Animals; Aotus trivirgatus; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Haplorhini; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine | 1978 |
Antimalarial activities of various 9-phenanthrenemethanols with special attention to WR-122,455 and WR-171,669.
Topics: Animals; Antimalarials; Chloroquine; Haplorhini; Humans; Malaria; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine | 1978 |
Plasmodium knowlesi: inhibition of invasion by pretreatment of erythrocytes with chloroquine and quinine.
Topics: Animals; Chloroquine; Erythrocytes; Haplorhini; In Vitro Techniques; Macaca mulatta; Osmotic Fragility; Plasmodium; Quinine | 1979 |
Resistance to antimalarials by Plasmodium falciparum in Burma.
Topics: Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria; Myanmar; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1977 |
Adenosine 3',5'-cyclic monophosphate and morphology in Neurospora crassa: drug-induced alterations.
Topics: Adenylyl Cyclases; Antimalarials; Atropine; Chloroquine; Cyclic AMP; Histamine; Kinetics; Neurospora; Neurospora crassa; Phosphoric Diester Hydrolases; Quinidine; Quinine; Theophylline | 1975 |
[Biological diagnosis of malaria and amebiasis].
Topics: Acetamides; Amebiasis; Chloroquine; Emetine; Entamoeba histolytica; Feces; Humans; Malaria; Methods; Nitroimidazoles; Primaquine; Quinine; Serologic Tests | 1977 |
Prevention and treatment of malaria.
Topics: Amodiaquine; Chloroquine; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Trimethoprim | 1977 |
[Chloroquine resistant tropical malaria imported from Surinam].
Topics: Chloroquine; Drug Resistance; Female; Humans; Malaria; Middle Aged; Netherlands; Plasmodium falciparum; Pyrimethamine; Quinine; Suriname; Travel | 1977 |
[Malaria; a summary].
Topics: Chloroquine; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine | 1978 |
Treatment of falciparum malaria in Thai children.
Topics: Child; Child, Preschool; Chloroquine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Thailand | 1979 |
Treatment and chemoprophylaxis of malaria.
Topics: Aminoquinolines; Antimalarials; Biguanides; Chloroquine; Dapsone; Humans; Malaria; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Quinine; Sulfonamides | 1979 |
Radical cure of infections with Plasmodium cynomolgi: a function of total 8-aminoquinoline dose.
Topics: Aminoquinolines; Animals; Antimalarials; Blood; Chloroquine; Female; Haplorhini; Macaca mulatta; Malaria; Male; Plasmodium; Primaquine; Quinine | 1977 |
[Drug-induced Lichen ruber planus].
Topics: Chloroquine; Gold; Humans; Lichen Planus; Methyldopa; Penicillamine; Quinine | 1979 |
Ototoxicity of commonly used pharmaceutical preparations.
Topics: Adolescent; Adult; Ampicillin; Antihypertensive Agents; Antineoplastic Agents; Aspirin; Child; Chloroquine; Deafness; Dextroamphetamine; Drug-Related Side Effects and Adverse Reactions; Humans; Magnoliopsida; Nigeria; Plants, Toxic; Prednisolone; Quinine; Streptomycin | 1979 |
Malaria--a red alert.
Topics: Aged; Child; Chloroquine; Drug Resistance; Drug Therapy, Combination; Health Education; Humans; Malaria; Pyrimethamine; Quinine; Sulfadiazine; Tetracycline; Travel | 1979 |
[Toxic retinopathies].
Topics: Chloroquine; Copper; Digitalis Glycosides; Epinephrine; Ethambutol; Humans; Immunosuppressive Agents; Indomethacin; Lysergic Acid Diethylamide; Ophthalmic Solutions; Phenothiazines; Quinine; Retinal Diseases; Siderosis | 1979 |
Proceedings: Pharmacology of Plasmodium berghei.
Topics: Chloroquine; Oligomycins; Plasmodium berghei; Quinine | 1975 |
Chloroquine-resistant falciparum malaria from Irian Jaya (Indonesian New Guinea).
Topics: Amodiaquine; Chloroquine; Drug Resistance; Humans; Malaria; Male; Piperidines; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Quinolines | 1976 |
Plasmodium berghei: phase contrast and electron microscopical evidence that certain antimalarials can both inhibit and reverse pigment clumping caused by chloroquine.
Topics: Animals; Antimalarials; Chloroquine; Cytoplasmic Granules; Erythrocytes; Female; Malaria; Mice; Phenanthrenes; Pigments, Biological; Piperidines; Plasmodium berghei; Quinine; Quinolines; Vacuoles | 1976 |
The chemotherapy of rodent malaria, XXVI. The potential value of WR 122,455 (a 9-phenanthrenemethanol) against drug-resistant malaria parasites.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Erythrocytes; Malaria; Male; Mice; Phenanthrenes; Piperidines; Plasmodium berghei; Quinine; Virulence | 1976 |
The search for new antimalarial drugs.
Topics: Animals; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Drug Evaluation, Preclinical; Haplorhini; Humans; Models, Chemical; Models, Structural; Plasmodium berghei; Plasmodium falciparum; Quinine; Rodentia | 1975 |
[Chemotherapy and chemoprophylaxis of malaria (author's transl)].
Topics: Adult; Amodiaquine; Antimalarials; Asia, Southeastern; Central America; Child; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfadoxine; Sulfalene; Travel | 1976 |
Changes in superhelical density of closed circular deoxyribonucleic acid by intercalation of anti-R-plasmid drugs and primaquine.
Topics: Acridines; Chemical Phenomena; Chemistry; Chloroquine; Chlorpromazine; DNA, Circular; Ethidium; Extrachromosomal Inheritance; Methylene Blue; Plasmids; Primaquine; Pseudomonas; Quinine | 1977 |
[Present-day problems of malaria. Prophylaxis and treatment].
Topics: Chloroquine; Drug Resistance; Female; Humans; Malaria; Male; Pregnancy; Quinine | 1977 |
Molecular structural effects involved in the interaction of quinolinemethanolamines with DNA. Implications for antimalarial action.
Topics: Amino Alcohols; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; DNA; Drug Interactions; Piperidines; Quinacrine; Quinine; Quinolines | 1977 |
Melanotropic drugs and retinal functions. I. Effects of quinine and chloroquine on the sheep ERG.
Topics: Animals; Chloroquine; Electroretinography; Pigment Epithelium of Eye; Quinine; Retina; Sheep | 1976 |
Chloroquine, quinine, procaine, quinidine and clomipramine are prostaglandin agonists and antagonists.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Chloroquine; Clomipramine; Dibenzazepines; Indomethacin; Male; Mesenteric Arteries; Norepinephrine; Procaine; Prostaglandin Antagonists; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Quinidine; Quinine; Rats | 1976 |
Letter: Unexplained fever.
Topics: Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Primaquine; Quinine | 1975 |
Rodent systems (Plasmodium berghei-Anopheles Stephensi) for screening compounds for potential causal prophylaxis.
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Drug Evaluation, Preclinical; Female; Malaria; Mice; Plasmodium berghei; Primaquine; Quinine; Quinolines; Rats | 1975 |
Falciparum malaria semi-resistant to clindamycin.
Topics: Blood; Child; Chloroquine; Clindamycin; Colitis; Digestive System; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male; Plasmodium falciparum; Quinine; Tetracycline | 1975 |
Sulfadoxine and pyrimethamine in the treatment of falciparum malaria in Vietnam.
Topics: Adolescent; Adult; Blood; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfanilamides; Time Factors; Vietnam | 1975 |
The chemotherapy of rodent malaria, XXII. The value of drug-resistant strains of P. berghei in screening for blood schizontocidal activity.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Chloroquine; Diamines; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Erythrocytes; Folic Acid Antagonists; Malaria; Male; Mice; Neuraminidase; Plasmodium berghei; Quinine; Sulfonamides; Sulfones; Virulence | 1975 |
Probable chloroquine-resistant Plasmodium falciparum malaria from Mozambique A case report.
Topics: Adult; Chloroquine; Drug Resistance, Microbial; Female; Humans; Malaria; Mozambique; Plasmodium falciparum; Quinine | 1975 |
Pharmacology of the malaria parasite--a study of dose-response relationships in chloroquine-induced autophagic vacuole formation in Plasmodium berghei.
Topics: Animals; Antimalarials; Binding Sites; Binding, Competitive; Chloroquine; Culture Media; Dose-Response Relationship, Drug; Erythrocytes; Kinetics; Mice; Pigments, Biological; Plasmodium berghei; Quinine; Structure-Activity Relationship | 1975 |
The experimental chemotherapy of leishmaniasis. II. The activity in tissue culture of some antiparasitic and antimicrobial compounds in clinical use.
Topics: Aminoquinolines; Animals; Anti-Bacterial Agents; Antimalarials; Antimony; Antiprotozoal Agents; Ascitic Fluid; Cell Line; Chloroquine; Cricetinae; Culture Techniques; Dogs; Drug Evaluation, Preclinical; Folic Acid Antagonists; Leishmania; Niridazole; Pentamidine; Primaquine; Quinacrine; Quinine; Sarcoma; Sulfonamides; Sulfones; Suramin | 1975 |
Malaria--general management as recommended by WHO.
Topics: Adult; Antimalarials; Child; Chloroquine; Drug Resistance; Humans; Malaria; Malaria, Cerebral; Malaria, Falciparum; Nursing Care; Quinine; Severity of Illness Index; World Health Organization | 1992 |
Sensitivity status of Plasmodium falciparum to chloroquine, amodiaquine, quinine, mefloquine and sulfadoxine/pyrimethamine in a tribal population of District Sundargarh, Orissa.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; India; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1992 |
[Treatment of malaria in children in France].
Topics: Antimalarials; Child; Chloroquine; France; Humans; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Phenanthrenes; Quinine | 1992 |
Incorporation of [3H]hypoxanthine by short-term cultured Theileria sergenti and its inhibition by drugs.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Cattle; Cells, Cultured; Chloroquine; Diminazene; Dose-Response Relationship, Drug; Erythrocytes; Hypoxanthine; Hypoxanthines; Immune Sera; Pyrimethamine; Quinine; Theileria | 1992 |
A new model for testing gametocytocidal effects of some antimalarial drugs on Plasmodium falciparum in vitro.
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; In Vitro Techniques; Models, Biological; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine | 1992 |
The combined effect of iron chelators and classical antimalarials on the in-vitro growth of Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Drug Synergism; Iron Chelating Agents; Plasmodium falciparum; Pyrimethamine; Quinine | 1992 |
Malariometric survey in Keoudom District, Laos: sensitivity of Plasmodium falciparum to anti-malarials and automedication with chloroquine.
Topics: Adolescent; Adult; Animals; Antibodies, Protozoan; Child; Child, Preschool; Chloroquine; Disease Reservoirs; Drug Resistance; Humans; Infant; Laos; Malaria, Falciparum; Microbial Sensitivity Tests; Middle Aged; Plasmodium falciparum; Quinine; Self Medication; Seroepidemiologic Studies | 1992 |
In vitro sensitivity of Plasmodium falciparum isolates in Thailand to quinine and chloroquine, 1984-1990.
Topics: Animals; Chloroquine; Drug Resistance; Humans; Plasmodium falciparum; Quinine; Thailand | 1992 |
Pathology of falciparum malaria in Vietnam.
Topics: Adult; Aged; Aged, 80 and over; Brain; Chloroquine; Female; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Quinine; Vietnam | 1992 |
Proposals for a new therapeutic strategy for simple Plasmodium falciparum malaria attacks in Cameroon.
Topics: Administration, Oral; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine | 1992 |
Mefloquine-halofantrine cross-resistance in Plasmodium falciparum induced by intermittent mefloquine pressure.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine | 1992 |
Assessment of chloroquine resistance of Plasmodium falciparum in children of Wad Medani (Central Sudan).
Topics: Adolescent; Animals; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; In Vitro Techniques; Infant; Injections, Intravenous; Malaria, Falciparum; Male; Plasmodium falciparum; Quinine; Sudan | 1992 |
Multi-drug resistant falciparum malaria in Cameroon in 1987-1988. I. Stable figures of prevalence of chloroquine- and quinine-resistant isolates in the original foci.
Topics: Animals; Cameroon; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Prevalence; Quinine | 1992 |
Unexpected response to treatment of falciparum malaria illness.
Topics: Adult; Antimalarials; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Quinine | 1992 |
Type RI resistance to halofantrine in West Africa.
Topics: Animals; Antimalarials; Biological Availability; Chloroquine; Cote d'Ivoire; Drug Resistance; Follow-Up Studies; France; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Phenanthrenes; Plasmodium falciparum; Quinine; Recurrence; Travel | 1991 |
Congenital malaria with chloroquine resistance.
Topics: Chloroquine; Drug Resistance; Female; Humans; Infant, Newborn; Malaria, Falciparum; Quinine | 1991 |
West African malaria.
Topics: Chloroquine; Female; Humans; Immunity, Innate; Malaria, Falciparum; Male; Middle Aged; Military Personnel; Quinine; Sierra Leone; Travel; United Kingdom | 1991 |
[Malaria in the republic of São Tomé and Principe. Epidemiologic evaluation and chemoresistance of P. falciparum].
Topics: Age Factors; Animals; Antimalarials; Atlantic Islands; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Seasons; Sex Factors; Splenomegaly | 1991 |
Severe falciparum malaria (21 cases).
Topics: Adolescent; Adult; Child, Preschool; Chloroquine; Exchange Transfusion, Whole Blood; Female; Humans; Infusions, Intravenous; Intensive Care Units; Malaria, Cerebral; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinine; Respiration, Artificial; Retrospective Studies | 1991 |
Drug use and design in the nineties.
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine | 1991 |
[Prevention and treatment of malaria in expatriates living in Black Africa. Influence of chemoresistance. Investigations conducted in Brazzaville (Congo)].
Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Congo; Drug Combinations; Drug Resistance, Microbial; Europe; Humans; Infant; Infant, Newborn; Malaria; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1991 |
Resistance to antimalarials by Plasmodium falciparum in Arso PIR, Irian Jaya, Indonesia.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Indonesia; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1991 |
Detection of antidrug IgG antibodies in patients with adverse drug reactions to amodiaquine.
Topics: Adult; Aged; Amodiaquine; Antibodies, Anti-Idiotypic; Chloroquine; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Malaria; Male; Middle Aged; Neutropenia; Primaquine; Quinine | 1991 |
Severe falciparum malaria in nonendemic areas: an unrecognized medical emergency.
Topics: Adult; Aged; Animals; Canada; Child, Preschool; Chloroquine; Communicable Disease Control; Emergencies; Female; Humans; Malaria; Male; Plasmodium falciparum; Quinine | 1991 |
Clinical and laboratory features of severe and complicated falciparum malaria the experience from Gonder Hospital.
Topics: Adolescent; Adult; Aged; Animals; Chloroquine; Ethiopia; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinine; Survival Rate | 1991 |
Chloroquine-resistant Plasmodium falciparum with reduced sensitivity in vitro to mefloquine and quinine in Zaria, northern Nigeria.
Topics: Animals; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Infant; Malaria; Mefloquine; Nigeria; Plasmodium falciparum; Quinine | 1991 |
Childhood cerebral malaria in Ibadan.
Topics: Acute Disease; Child; Child, Preschool; Chloroquine; Coma; Female; Humans; Infant; Malaria; Male; Nigeria; Quinine | 1991 |
The chemical basis for the ferriprotoporphyrin IX-chloroquine complex induced lipid peroxidation.
Topics: Animals; Antimalarials; Apoproteins; Benzoates; Benzoic Acid; Catalase; Chloroquine; Hemin; Hydrogen-Ion Concentration; Iron; Kinetics; Lipid Peroxidation; Liposomes; Mefloquine; Oxygen; Primaquine; Quinine; Rats; Spectrum Analysis; Superoxide Dismutase; Transferrin | 1991 |
Widespread in vitro resistance to chloroquine of Plasmodium falciparum in the Congo, 1987.
Topics: Adolescent; Animals; Child; Child, Preschool; Chloroquine; Congo; Drug Resistance; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Quinine; Regression Analysis | 1991 |
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Butylated Hydroxytoluene; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Mefloquine; Molecular Structure; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Sesquiterpenes; Thailand | 1991 |
[Imported malaria in Bordeaux in 1989. Epidemiologic, clinical and therapeutic study of 71 cases].
Topics: Animals; Antimalarials; Chloroquine; Female; France; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Travel | 1990 |
An in-vitro profile of the action of four antimalarials on indigenous cases of Plasmodium falciparum malaria in Karnataka.
Topics: Amodiaquine; Animals; Chloroquine; Drug Resistance, Microbial; Malaria; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine | 1990 |
[A case of Plasmodium falciparum malaria contracted in Guinea-Bissau during chemoprophylaxis with chloroquine].
Topics: Animals; Chloroquine; Drug Resistance; Female; Humans; Malaria; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine | 1990 |
[Uncomplicated attack of malaria in an area with high resistance to chloroquine. I. Evaluation of a short treatment with quinine].
Topics: Adolescent; Animals; Cameroon; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Infant; Malaria; Male; Plasmodium falciparum; Quinine | 1990 |
[Plasmodium falciparum drug resistance in the Congo. Evaluation of surveys carried out from 1985 to 1989].
Topics: Adolescent; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Congo; Drug Combinations; Drug Resistance; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1990 |
Role of endocytosis in the action of ether lipids on WEHI-3B, HL60, and FDCP-mix A4 cells.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Survival; Chloroquine; Diltiazem; Drug Synergism; Endocytosis; Furans; Humans; Hydroxyzine; In Vitro Techniques; Leukemia, Myeloid; Mice; Nifedipine; Phospholipid Ethers; Platelet Activating Factor; Pyridines; Quinidine; Quinine; Sodium Fluoride; Thiazoles; Triazoles; Verapamil | 1990 |
Potentiation of chloroquine activity against Plasmodium falciparum by the peroxidase-hydrogen peroxide system.
Topics: Animals; Cells, Cultured; Chloroquine; Drug Synergism; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Mefloquine; Peroxidases; Plasmodium falciparum; Quinine | 1990 |
A nuclear magnetic resonance study of the interactions of the antimalarials chloroquine, quinacrine, quinine and mefloquine with lipids extracted from normal human erythrocytes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antimalarials; Chloroquine; Deuterium; Erythrocytes; Humans; Magnetic Resonance Spectroscopy; Mefloquine; Membrane Lipids; Phosphatidylethanolamines; Phosphorus Isotopes; Quinacrine; Quinine | 1990 |
Effects of chloroquine, mefloquine and quinine on natural killer cell activity in vitro. An analysis of the inhibitory mechanism.
Topics: Cell Adhesion; Chloroquine; Cytotoxicity, Immunologic; Humans; Immunity, Cellular; Immunity, Innate; In Vitro Techniques; Interferons; Interleukin-2; Killer Cells, Natural; Mefloquine; Quinine; Quinolines | 1986 |
[Chloroquine-resistant Plasmodium falciparum malaria confirmed by semi-micro sensitivity test for chloroquine seen in a person returned from Nigeria to Japan].
Topics: Adult; Animals; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Male; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Travel | 1989 |
[Comparative efficacy of alternative treatments in Plasmodium falciparum infections in Zaire].
Topics: Animals; Antimalarials; Child, Preschool; Chloroquine; Democratic Republic of the Congo; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1989 |
[Surveillance of Plasmodium falciparum drug sensitivity in Yaounde and its surroundings (Cameroon). In vivo and in vitro study].
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Chloroquine; Humans; In Vitro Techniques; Infant; Malaria; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Plasmodium falciparum; Quinine; Quinolines; Rural Population | 1989 |
[Malaria in Guiana. I. General status of the endemic].
Topics: Adolescent; Adult; Amodiaquine; Animals; Child; Child, Preschool; Chloroquine; Drug Resistance; French Guiana; History, 17th Century; History, 19th Century; History, 20th Century; Humans; Infant; Malaria; Plasmodium falciparum; Plasmodium vivax; Quinine | 1989 |
Chloroquine in the treatment of malaria.
Topics: Animals; Chloroquine; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Quinine | 1989 |
Chloroquine-resistant malaria in Jos, Nigeria.
Topics: Adolescent; Animals; Brain Diseases; Chloroquine; Drug Resistance; Humans; Malaria; Male; Nigeria; Plasmodium falciparum; Quinine | 1989 |
[A very severe Plasmodium falciparum infection in spite of malaria prophylaxis].
Topics: Animals; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Proguanil; Quinine | 1989 |
[Sensitivity of Plasmodium falciparum to different antimalarials. A study in 1988 in a village in the Hauts-Plateaux of Madagascar].
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Madagascar; Mefloquine; Plasmodium falciparum; Quinine | 1989 |
Curative and preventive treatment of uncomplicated malaria in public health institutions in Cameroon.
Topics: Amodiaquine; Antimalarials; Cameroon; Child; Chloroquine; Drug Combinations; Female; Humans; Malaria; Medicine; Nurses; Physicians; Pregnancy; Public Health; Pyrimethamine; Quinine; Specialization; Sulfadoxine; Surveys and Questionnaires | 1989 |
A nuclear magnetic resonance study of the interactions of the antimalarials chloroquine, quinacrine, quinine and mefloquine with dipalmitoylphosphatidylcholine bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antimalarials; Chloroquine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Mefloquine; Quinacrine; Quinine; Quinolines; Temperature | 1989 |
Drug induced alterations in some rat hepatic microsomal components: a comparative study of four structurally different antimalarials.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Antimalarials; Aryl Hydrocarbon Hydroxylases; Chloroquine; Cholesterol; Cytosol; Glutathione Transferase; Liver; Male; Microsomes, Liver; Phospholipids; Primaquine; Quinacrine; Quinine; Rats; Rats, Inbred Strains | 1985 |
[Retinal diseases].
Topics: Anti-Bacterial Agents; Antimalarials; Antineoplastic Agents; Antipsychotic Agents; Canthaxanthin; Carotenoids; Chloroquine; Contraceptives, Oral; Deferoxamine; Digitalis Glycosides; Epinephrine; Humans; Indomethacin; Macula Lutea; Miotics; Phenothiazines; Quinine; Retinal Diseases | 1985 |
High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand.
Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Chloroquine; Female; Follow-Up Studies; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Quinidine; Quinine; Quinolines; Recurrence; Thailand | 1987 |
Effects of indole alkaloids on multidrug resistance and labeling of P-glycoprotein by a photoaffinity analog of vinblastine.
Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Survival; Chloroquine; Drug Interactions; Drug Resistance; Humans; Indoles; Leukemia; Membrane Glycoproteins; Photochemistry; Quinacrine; Quinine; Reserpine; Verapamil; Vinblastine; Vinca Alkaloids; Vindesine; Yohimbine | 1988 |
In vitro sensitivity of Plasmodium falciparum isolates from Burma to chloroquine quinine and mefloquine.
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Mefloquine; Myanmar; Plasmodium falciparum; Quinine; Quinolines | 1985 |
Inhibition of phosphatidylinositol phosphodiesterase activity in skeletal muscle by metal ions and drugs which block neuromuscular transmission.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Calcium; Chloroquine; Humans; In Vitro Techniques; Metals; Muscles; Neuromuscular Blocking Agents; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Quinine | 1985 |
[In vitro activity of various antimalarials (chloroquine, amodiaquine, quinine and mefloquine) against 32 isolates of Plasmodium falciparum in French Guiana].
Topics: Amodiaquine; Animals; Chloroquine; Drug Resistance; French Guiana; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1988 |
Response of Kampuchean strains of Plasmodium falciparum to antimalarials: in-vivo assessment of quinine and quinine plus tetracycline; multiple drug resistance in vitro.
Topics: Adolescent; Adult; Animals; Cambodia; Chloroquine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Humans; In Vitro Techniques; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine; Quinolines; Tetracycline | 1988 |
Patterns of in vitro resistance to chloroquine, quinine, and mefloquine of Plasmodium falciparum in Cameroon, 1985-1986.
Topics: Adolescent; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Infant; Mefloquine; Plasmodium falciparum; Quinine; Quinolines; Time Factors | 1988 |
Serial studies on the evolution of drug resistance in malaria in an area of east Africa: findings from 1979 up to 1986.
Topics: Age Factors; Amodiaquine; Animals; Antibodies, Protozoan; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Quinolines; Sulfadoxine; Tanzania | 1988 |
Malaria prophylaxis.
Topics: Animals; Chloroquine; Drug Resistance; Humans; Malaria; New Zealand; Plasmodium falciparum; Quinine | 1988 |
A rapid in vitro assay system using anti-bromodeoxyuridine for drug susceptibility of Plasmodium falciparum.
Topics: Animals; Bromodeoxyuridine; Chloroquine; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Plasmodium falciparum; Pyrimethamine; Quinine | 1988 |
Antagonism of chloroquine with other antimalarials.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Interactions; Drug Resistance; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1988 |
[An imported case of malaria resistant to chloroquine].
Topics: Animals; Cameroon; Child; Child, Preschool; Chloroquine; Doxycycline; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Israel; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1988 |
Chloroquine-resistant Plasmodium falciparum in Mali revealed by congenital malaria.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance; Female; Humans; Infant, Newborn; Malaria; Mali; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1988 |
Multiple drug resistant Plasmodium falciparum malaria in a pregnant indigenous Zambian woman.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Erythromycin; Female; Humans; Malaria; Mefloquine; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 1988 |
Death despite malaria prophylaxis.
Topics: Adult; Animals; Chloroquine; Humans; Malaria; Male; Plasmodium falciparum; Proguanil; Quinine; Travel | 1988 |
Death despite malaria prophylaxis.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1988 |
Death despite malaria prophylaxis.
Topics: Animals; Chloroquine; Humans; Malaria; Male; Plasmodium falciparum; Quinine | 1988 |
Reduction in morphological sickling of red cells incubated with quinine.
Topics: Anemia, Sickle Cell; Chloroquine; Cyanates; Drug Synergism; Erythrocytes, Abnormal; Humans; Quinine | 1987 |
Evaluation of an in vitro assay system for drug susceptibility of field isolates of Plasmodium falciparum from southern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Butylated Hydroxytoluene; Chloroquine; Humans; Mefloquine; Parasitology; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Quinolines; Thailand; Triazines | 1988 |
In vitro activity of pyronaridine against field isolates and reference clones of Plasmodium falciparum.
Topics: Amodiaquine; Animals; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Drug Resistance; Humans; Mefloquine; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Thailand | 1988 |
Effects of quinoline-containing antimalarials on the erythrocyte membrane and their significance to drug action on Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Erythrocyte Membrane; Hemolysis; Humans; Hydrogen-Ion Concentration; Mefloquine; Phospholipids; Plasmodium falciparum; Potassium; Proteins; Quinine; Quinolines | 1988 |
In vitro susceptibility of Plasmodium falciparum to amodiaquine, mefloquine, quinine and chloroquine in Liberia, West Africa.
Topics: Amodiaquine; Animals; Chloroquine; Drug Resistance; Liberia; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
Severe chloroquine-resistant falciparum malaria in Gabon with decreased sensitivity to quinine.
Topics: Adult; Chloroquine; Drug Resistance; Female; Gabon; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinine | 1986 |
Quinine resistant falciparum malaria in Vanuatu? A case report.
Topics: Animals; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Malaria; Male; Melanesia; Plasmodium falciparum; Quinine | 1987 |
Clinical evaluation of antimalarial regimens in Japan.
Topics: Animals; Antimalarials; Chloroquine; Drug Therapy, Combination; Humans; Japan; Malaria; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Prognosis; Pyrimethamine; Quinine; Recurrence; Sulfonamides; Surveys and Questionnaires | 1987 |
Plasmodium falciparum in Kinshasa, Zaire: in vitro drug susceptibility studies.
Topics: Animals; Child; Chloroquine; Democratic Republic of the Congo; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine | 1987 |
In vitro drug response of Plasmodium falciparum in the Philippines: increased resistance to amodiaquine.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Philippines; Plasmodium falciparum; Quinine; Quinolines | 1987 |
Flunarizine and verapamil inhibit chloroquine-resistant Plasmodium falciparum growth in vitro.
Topics: Animals; Antimalarials; Chloroquine; Chlorpromazine; Drug Resistance; Flunarizine; Mefloquine; Plasmodium falciparum; Quinine; Quinolines; Regression Analysis; Verapamil | 1987 |
Low sensitivity to chloroquine and quinine of Plasmodium falciparum isolates from Guinea in March 1986.
Topics: Africa, Western; Animals; Chloroquine; Drug Resistance; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Plasmodium falciparum; Quinine | 1987 |
[Sensitivity of Plasmodium falciparum to quinolines and therapeutic strategies: comparison of the situation in Africa and Madagascar between 1983 and 1986].
Topics: Amodiaquine; Angola; Animals; Antimalarials; Burkina Faso; Cameroon; Chloroquine; Drug Resistance; Humans; Madagascar; Malaria; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1987 |
[Current aspects of imported drug-resistant Plasmodium falciparum].
Topics: Adult; Africa, Central; Aged; Aged, 80 and over; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; France; Humans; Malaria; Middle Aged; Military Personnel; Plasmodium falciparum; Quinine | 1987 |
Compared response to chloroquine, fansidar, quinine, and quinidine slow release of infections with Plasmodium falciparum in the Kivu region of Zaire.
Topics: Animals; Antimalarials; Chloroquine; Delayed-Action Preparations; Democratic Republic of the Congo; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Sulfadoxine; Sulfanilamides | 1987 |
Effect of antimalarial drugs on stimulation and interleukin 2 production of human lymphocytes.
Topics: Antimalarials; Candida; Cells, Cultured; Chloroquine; Drug Administration Schedule; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mefloquine; Protein Biosynthesis; Pyrimethamine; Quinine; Quinolines; Tuberculin | 1987 |
Reduced efficacy of chemotherapy of Plasmodium chabaudi in T cell-deprived mice.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Lymphocyte Depletion; Malaria; Mice; Mice, Inbred CBA; Pyrimethamine; Quinine; T-Lymphocytes | 1987 |
Vivax malaria.
Topics: Acute Disease; Adult; Cambodia; Chloroquine; Emergencies; Emigration and Immigration; Female; Fluid Therapy; Humans; Malaria; Male; Middle Aged; Plasmodium vivax; Quinine; Time Factors; Vietnam | 1986 |
Polyresistant malaria in Gurkha soldiers returning from Papua New Guinea: treatment and prevention.
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Ethnicity; Hong Kong; Humans; Malaria; Male; Military Personnel; Nepal; Oxytetracycline; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Primaquine; Proguanil; Quinine; United Kingdom | 1986 |
High level of sensitivity to chloroquine of 72 Plasmodium falciparum isolates from southern Cameroon in January 1985.
Topics: Animals; Antimalarials; Cameroon; Child; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
Decreased sensitivity to chloroquine and quinine of some Plasmodium falciparum strains from Senegal in September 1984.
Topics: Adolescent; Animals; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Quinine; Senegal | 1986 |
Digestion of the host erythrocyte by malaria parasites is the primary target for quinoline-containing antimalarials.
Topics: Amino Acids; Ammonium Chloride; Animals; Antimalarials; Chloroquine; Erythrocytes; Host-Parasite Interactions; Humans; Mefloquine; Methylamines; Plasmodium falciparum; Quinine; Quinolines; Vacuoles | 1986 |
Imported cases of chloroquine-resistant falciparum malaria in Iran.
Topics: Adolescent; Adult; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Iran; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadiazine; Sulfadoxine; Travel | 1986 |
Serious problems with antimalarial drugs.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfadoxine | 1986 |
The efficacy of artemether (qinghaosu) in Plasmodium falciparum and P. vivax in Burma.
Topics: Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrans; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 1986 |
Chloroquine-resistant malaria. A case report.
Topics: Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinine | 1986 |
[A Parisian case of congenital malaria].
Topics: Chloroquine; Female; Humans; Infant, Newborn; Malaria; Maternal-Fetal Exchange; Paris; Plasmodium vivax; Pregnancy; Quinine | 1986 |
[Preliminary study, in vitro, of the sensitivity of P. falciparum to chloroquine, mefloquine and quinine during 1985, in Kampuchea].
Topics: Adult; Antimalarials; Cambodia; Chloroquine; Humans; Malaria; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Quinolines | 1986 |
In vitro effect of chloroquine, mefloquine and quinine on human lymphocyte proliferative responses to malaria antigens and other antigens/mitogens.
Topics: Adult; Antigens, Fungal; Antigens, Protozoan; Candida albicans; Chloroquine; Humans; Lymphocyte Activation; Mefloquine; Mitogens; Plasmodium falciparum; Quinine; Quinolines; Tuberculin | 1986 |
Effects of combinations of quinoline-containing antimalarials on Plasmodium falciparum in culture.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Interactions; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
Chloroquine-resistant falciparum malaria from East Africa.
Topics: Adult; Africa, Eastern; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 1986 |
A combination of sulfamonomethoxine and pyrimethamine versus other drugs for the treatment of malaria.
Topics: Adolescent; Adult; Aged; Chloroquine; Drug Combinations; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfadoxine; Sulfamonomethoxine; Sulfanilamides | 1986 |
Plasmodium falciparum drug resistance in West Africa.
Topics: Africa, Western; Animals; Antimalarials; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
[Development of P. falciparum sensitivity to chloroquine, to quinine and to mefloquine between 1983 and 1985 in Zaire].
Topics: Animals; Antimalarials; Chloroquine; Democratic Republic of the Congo; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1986 |
Antimalarial drug susceptibility testing of Plasmodium falciparum in Thailand using a microdilution radioisotope method.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Lethal Dose 50; Malaria; Male; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Quinolines; Thailand | 1985 |
Studies of resistance to chloroquine, quinine, amodiaquine and mefloquine among Philippine strains of Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Mefloquine; Philippines; Plasmodium falciparum; Quinine; Quinolines | 1985 |
Mefloquine failure in a case of falciparum malaria induced with a multidrug-resistant isolate in a non-immune subject.
Topics: Adult; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Pyridines; Quinine; Quinolines | 1985 |
Chloroquine-resistant Plasmodium falciparum malaria in South Africa. A case report.
Topics: Adolescent; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium falciparum; Quinine; Tetracycline | 1985 |
Malaria prophylaxis for Canadian travellers.
Topics: Amodiaquine; Canada; Chloroquine; Dapsone; Doxycycline; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Infant; Infant, Newborn; Malaria; Plasmodium; Plasmodium falciparum; Pregnancy; Premedication; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Travel | 1985 |
Antimalarials increase vesicle pH in Plasmodium falciparum.
Topics: Ammonia; Animals; Antimalarials; Biological Transport; Chloroquine; Erythrocytes; Hydrogen-Ion Concentration; Lysosomes; Mefloquine; Organoids; Plasmodium falciparum; Quinine; Quinolines | 1985 |
[Sensitivity of strains of Plasmodium falciparum to chloroquine, mefloquine and quinine in 1983 in Zaire].
Topics: Animals; Antimalarials; Chloroquine; Democratic Republic of the Congo; Drug Resistance, Microbial; In Vitro Techniques; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1985 |
Plasmodium falciparum in Madagascar: in vivo and in vitro sensitivity to seven drugs.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Humans; Infant; Madagascar; Malaria; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines | 1985 |
[In vivo and in vitro sensitivity to 4-aminoquinolines of Plasmodium falciparum in Madagascar: results of 2 years' study].
Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Madagascar; Malaria; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines | 1985 |
Failure of large-dose erythromycin in combination with a standard dose of chloroquine or quinine in the treatment of human falciparum malaria.
Topics: Adult; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Erythromycin; Humans; Malaria; Male; Plasmodium falciparum; Quinine; Thailand | 1985 |
Drug-resistant malaria--changing patterns mean difficult decisions.
Topics: Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Humans; Infant; Kenya; Malaria; Microbial Sensitivity Tests; Plasmodium; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sulfadoxine | 1985 |
[Malaria chemoprophylaxis. Resistance problems].
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 1985 |
Effects of lysosomotropic agents on lipogenesis.
Topics: Acetates; Ammonium Chloride; Cells, Cultured; Chloroquine; Choline; Cycloheximide; Fibroblasts; Humans; Hydrogen-Ion Concentration; Lipids; Lysosomes; Palmitates; Pyruvates; Quinine; Water | 1986 |
A nuclear magnetic resonance study of the interactions of antimalarial drugs with porphyrins.
Topics: Chloroquine; Heme; Hemin; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Porphyrins; Quinine; Uroporphyrins | 1985 |
[Tactics and strategy of malaria control].
Topics: Animals; Anopheles; Chloroquine; Developing Countries; Female; Humans; Malaria; Mosquito Control; Quinine; Socioeconomic Factors | 1985 |
Ototoxic drugs: a review of clinical aspects, histopathologic changes and mechanisms of action.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Aspirin; Chloroquine; Cochlea; Dihydrostreptomycin Sulfate; Ear, Inner; Ethacrynic Acid; Female; Hearing Disorders; Humans; Kanamycin; Neomycin; Poisons; Pregnancy; Quinine; Streptomycin | 1971 |
Mechanism of drug-induced chronic otic lesions. Role of drug accumulation on the melanin of the inner ear.
Topics: Animals; Anti-Infective Agents; Carbon Radioisotopes; Chloroquine; Dihydrostreptomycin Sulfate; Ear, Inner; Female; Fetus; Kanamycin; Labyrinth Diseases; Maternal-Fetal Exchange; Melanins; Mice; Pregnancy; Quinine; Streptomycin; Viomycin | 1973 |
Effect of quinoline, phthalazine and coumarin derivatives on the absorbance of NADPH.
Topics: Chloroquine; Coumarins; Heterocyclic Compounds; Hydralazine; Indophenol; NADP; Novobiocin; Quinacrine; Quinidine; Quinine; Quinolines; Spectrophotometry; Warfarin | 1974 |
Observations on the binding site for antimalarial schizontocides.
Topics: Antimalarials; Binding Sites; Binding, Competitive; Chloroquine; Ephedrine; Isoproterenol; Plasmodium berghei; Quinine | 1973 |
Effects of antimalarial drugs and clofibrate on in vitro lipid synthesis in Tetrahymena pyriformis GL.
Topics: Acetates; Adenosine Triphosphate; Carbon Radioisotopes; Cell Division; Cell-Free System; Chloroquine; Chromatography, Thin Layer; Clofibrate; Depression, Chemical; Fatty Acids, Nonesterified; Lipids; NADH, NADPH Oxidoreductases; Phospholipids; Primaquine; Quinacrine; Quinine; Stimulation, Chemical; Tetrahymena pyriformis; Triglycerides | 1974 |
Chloroquine-resistant falciparum malaria in Thailand.
Topics: Adolescent; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Humans; Infant; Malaria; Plasmodium falciparum; Quinacrine; Quinine; Thailand | 1965 |
125-I-labelled fibrinogen in cerebral malaria.
Topics: Adolescent; Adult; Blood Coagulation; Brain Diseases; Chloroquine; Drug Resistance, Microbial; Fibrinogen; Humans; Injections, Intravenous; Iodine Isotopes; Liver Function Tests; Malaria; Middle Aged; Plasmodium falciparum; Prothrombin Time; Quinine; Thailand | 1966 |
Choroquine-resistant Plasmodium falciparum malaria in the United Kingdom.
Topics: Adult; Chloroquine; England; Humans; Malaria; Malaysia; Male; Penicillin Resistance; Penicillins; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Sulfonamides | 1968 |
Drug-resistant malaria.
Topics: Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine; Sulfonamides | 1969 |
The effects of antimalarial drugs on nucleic acid synthesis in vitro in Tetrahymena pyriformis.
Topics: Animals; Antimalarials; Cell Nucleus; Chloroquine; Dactinomycin; DNA; DNA Nucleotidyltransferases; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Guanosine Triphosphate; Primaquine; Quinine; RNA; Tetrahymena pyriformis; Tritium | 1973 |
Experience with mixed infections of Plasmodium falciparum and vivax.
Topics: Antimalarials; Chloroquine; Dapsone; Humans; Malaria; Military Medicine; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine; Sulfisoxazole; United States; Vietnam | 1973 |
Response to treatment in man of multi-drug resistant Plasmodium falciparum from Panama.
Topics: Adult; Amodiaquine; Animals; Anopheles; Antimalarials; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Haplorhini; Humans; Malaria; Male; Panama; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Recurrence; Sulfadiazine | 1974 |
Infections with Plasmodium falciparum and Plasmodium vivax in the owl monkey--model systems for basic biological and chemotherapeutic studies.
Topics: Animal Feed; Animals; Butylamines; Chlorobenzenes; Chloroquine; Colombia; Darkness; Disease Models, Animal; Drug Resistance, Microbial; Haplorhini; Humans; Injections, Intravenous; Malaria; Methanol; Methods; Piperidines; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quarantine; Quinine; Quinolines; Splenectomy | 1973 |
[Prevention and treatment of malaria. 1. Analysis of 73 cases of malaria in Japan].
Topics: Adult; Chloroquine; Humans; Japan; Malaria; Middle Aged; Primaquine; Quinine | 1973 |
Coombs'-positive hemolytic disease in malaria.
Topics: Adrenal Cortex Hormones; Adult; Anemia, Hemolytic; Antibodies; Chloroquine; Coombs Test; Drug Eruptions; Drug Resistance, Microbial; Erythrocytes; Hematocrit; Humans; Malaria; Male; Pyrimethamine; Quinine; Sulfadiazine | 1968 |
Characterization of a drug resistant strain of Plasmodium falciparum from Burma.
Topics: Adult; Amodiaquine; Anopheles; Chloroquine; Drug Resistance, Microbial; Human Experimentation; Humans; Insect Vectors; Malaria; Male; Myanmar; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine | 1973 |
Inactivation of lysosomal function in normal cultured human fibroblasts by chloroquine.
Topics: Cell Survival; Cells, Cultured; Chloroquine; Fibroblasts; Glycosaminoglycans; Humans; Hydrogen-Ion Concentration; Lysosomes; Microscopy, Electron; Quinacrine; Quinine; Sulfur Radioisotopes; Time Factors | 1973 |
Antihistaminic activity of synthetic quinoline derivatives.
Topics: Acridines; Animals; Chloroquine; Guinea Pigs; Histamine H1 Antagonists; Pyridines; Quinine; Quinolines | 1971 |
Effect of antimalarial drugs on the efflux of K+ from Streptococcus pyogenes.
Topics: Antimalarials; Biological Transport; Cell Membrane Permeability; Chloroquine; Culture Media; Potassium; Potassium Isotopes; Primaquine; Quinacrine; Quinine; Streptococcus pneumoniae; Streptococcus pyogenes | 1971 |
[UV-spectrophotometry in drug control. 14. Characterization and determination of drugs with quinoline and isoquinoline chromophores].
Topics: Amodiaquine; Chloroquine; Hydroxychloroquine; Isoquinolines; Papaverine; Primaquine; Quinidine; Quinine; Quinolines; Spectrophotometry, Ultraviolet | 1974 |
Plasmodium falciparum malaria in Panama resistant to 4-aminoquinoline drugs.
Topics: Amodiaquine; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Panama; Plasmodium falciparum; Quinine; Quinolines; Time Factors | 1972 |
Malaria--again a diagnostic consideration.
Topics: Chloroquine; Diagnosis, Differential; Erythrocytes; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Primaquine; Quinine | 1972 |
Malaria.
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Fluorescent Antibody Technique; Humans; Immunoglobulins; Malaria; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Quinine | 1972 |
Preliminary studies on a Philippine strain of Plasmodium falciparum resistant to amodiaquine.
Topics: Adult; Amodiaquine; Body Weight; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Philippines; Plasmodium falciparum; Quinine | 1972 |
A model in vitro system to test the susceptibility of human malarial parasites to antimalarial drugs.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Trimethoprim | 1972 |
Relapses of vivax malaria after a conventional course of primaquine and chloroquine: report of 2 cases.
Topics: Adult; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Glucosephosphate Dehydrogenase; Hemolysis; Humans; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Primaquine; Quinine; Recurrence; Time Factors | 1973 |
Ferrokinetics in patients with malaria: normoblasts and iron incorporation in vitro.
Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Cell Count; Cells, Cultured; Chloroquine; Erythropoiesis; Female; Humans; In Vitro Techniques; Iron; Iron Isotopes; Malaria; Male; Methods; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Primaquine; Quinine | 1973 |
Characterisation of a drug resistant strain of Plasmodium falciparum from Sabah.
Topics: Adult; Amodiaquine; Borneo; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine | 1973 |
Experimental infection in man with Plasmodium malariae.
Topics: Adult; Animals; Anopheles; Chloroquine; Disease Vectors; Humans; Informed Consent; Injections, Intravenous; Malaria; Male; Nigeria; Philippines; Plasmodium malariae; Quinine; Time Factors | 1973 |
Five day primaquine therapy--an evaluation of radical curative activity against vivax malaria infection.
Topics: Chloroquine; Evaluation Studies as Topic; Humans; India; Malaria; Male; Pakistan; Plasmodium vivax; Primaquine; Quinine; Time Factors | 1973 |
Chloroquine-resistant Falciparum malaria acquired in Vietnam.
Topics: Acute Kidney Injury; Adolescent; Adult; Blood Cell Count; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Leukopenia; Liver Diseases; Liver Function Tests; Malaria; Male; Military Medicine; Plasmodium falciparum; Proteinuria; Pulmonary Edema; Pyrimethamine; Quinine; Thrombocytopenia; Vietnam | 1973 |
Characteristics of Plasmodium falciparum from the Solomon Islands.
Topics: Anopheles; Blood; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Pacific Islands; Plasmodium falciparum; Pyrimethamine; Quinine | 1974 |
The chemotherapy and prophylaxis of malaria.
Topics: Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Female; Humans; Infant; Infant, Newborn; Malaria; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Pregnancy; Primaquine; Proguanil; Quinine | 1973 |
Letter: Quinine and chloroquine antagonism in falciparum malaria.
Topics: Chloroquine; Humans; Malaria; Plasmodium falciparum; Quinine | 1973 |
Multidrug-resistant strain of Plasmodium falciparum from eastern Colombia.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Colombia; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Malaria; Male; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfadiazine | 1974 |
A survey of imported malaria in Western Australia including four cases of drug resistance.
Topics: Adolescent; Adult; Australia; Brain Diseases; Chloroquine; Drug Resistance, Microbial; Emigration and Immigration; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Quinine; Time Factors; Travel | 1974 |
A comparison between the quinine and chloroquine regimens for falciparum malaria in Vietnam.
Topics: Administration, Oral; Chloroquine; Dapsone; Humans; Injections, Intravenous; Malaria; Male; Military Medicine; Naval Medicine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfisoxazole; United States; Vietnam | 1974 |
Some pharmacological aspects of antimalarial drugs.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfonamides; Trimethoprim | 1974 |
[Treatment of drug-resistant malaria: animal experiments].
Topics: Amodiaquine; Animals; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Folic Acid Antagonists; Leucomycins; Malaria; Mice; Plasmodium berghei; Pyrimethamine; Quinine; Quinolines; Time Factors | 1974 |
Acute falciparum malaria. Complications and treatment.
Topics: Acute Kidney Injury; Brain Diseases; Chloroquine; Coma; Disseminated Intravascular Coagulation; Heparin; Humans; Malaria; Plasmodium falciparum; Quinine; Thrombocytopenia | 1974 |
Experiences with malaria in the early phase of Australian army involvement in South Vietnam.
Topics: Administration, Oral; Australia; Chloroquine; Humans; Injections, Intravenous; Malaria; Male; Military Medicine; Plasmodium falciparum; Plasmodium vivax; Proguanil; Quinine; Vietnam; Warfare | 1974 |
Recrudescence, poor response or resistance to quinine of falciparum malaria in Thailand.
Topics: Administration, Oral; Adult; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Injections, Intravenous; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Recurrence; Sulfadoxine; Thailand | 1974 |
The effects of antimalarial drugs on uptake and incorporation of macromolecular precursors by Tetrahymena pyriformis.
Topics: Amino Acids; Animals; Antimalarials; Carbon Isotopes; Cell Division; Chloroquine; Cycloheximide; Dactinomycin; DNA; Kinetics; Macromolecular Substances; Nalidixic Acid; Primaquine; Quinacrine; Quinine; RNA; Tetrahymena pyriformis; Thymidine; Uridine | 1972 |
Studies on the characterization of plasmodium vivax strains from Central America.
Topics: Animals; Central America; Chloroquine; Haplorhini; Humans; Lincomycin; Malaria; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinine; Recurrence; Time Factors | 1972 |
Electrodiagnostic procedures in drug-induced ocular diseases.
Topics: Chloroquine; Electrodiagnosis; Electrooculography; Electroretinography; Evoked Potentials; Eye; Humans; Indomethacin; Photic Stimulation; Quinine; Retinal Diseases; Time Factors | 1973 |
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro.
Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts | 1973 |
[Etiology and pathogenesis of toxic side-effects of drugs on the retina (author's transl)].
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Agents; Cardiac Glycosides; Cats; Chloramphenicol; Chloroquine; Contraceptives, Oral; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Melanins; Phenothiazines; Protein Binding; Quinine; Retinal Diseases | 1973 |
Similarities between antimalarial schizontocides.
Topics: Antimalarials; Binding Sites; Chloroquine; Quinacrine; Quinine; Structure-Activity Relationship | 1973 |
In vitro inhibition of protein synthesis in the retinal pigment epithelium by chloroquine.
Topics: Animals; Carbon Radioisotopes; Cattle; Chloroquine; Cycloheximide; Epithelium; Eye Proteins; Hydroxychloroquine; In Vitro Techniques; Leucine; Lysine; Phenylalanine; Puromycin; Quinine; Retina; Tissue Extracts | 1974 |
[A febrile crisis of suspected malarial etiology in a person returning from the tropics].
Topics: Antimalarials; Blood; Chloroquine; Drug Synergism; Fever; Humans; Liver Function Tests; Malaria; Plasmodium; Quinine | 1974 |
[Chloroquine-resistant malignant malaria].
Topics: Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Quinine; South America | 1967 |
Treatment of acute falciparum malaria with sulfalene and trimethoprim.
Topics: Chloroquine; Folic Acid Antagonists; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Quinine; Sulfonamides | 1968 |
Apparent chloroquine-resistant falciparum malaria from coastal Brazil.
Topics: Brazil; Chloroquine; Drug Resistance, Microbial; Geography; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadiazine | 1968 |
Early experiences in the treatment of falciparum malaria from Southeast Asia.
Topics: Asia, Southeastern; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Military Medicine; Plasmodium malariae; Pyrimethamine; Quinine | 1968 |
Surveys on chloroquine resistant P. falciparum in Thailand.
Topics: Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium; Plasmodium falciparum; Plasmodium vivax; Quinine; Thailand | 1968 |
The sporogonous of Plasmodium vivax in Anopheles mosquitoes as a system for evaluating the prophylactic and curative capabilities of potential antimalarial compounds.
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Malaria; Naphthoquinones; Oxytetracycline; Penicillin G; Plasmodium vivax; Primaquine; Proguanil; Pyridines; Pyrimethamine; Quinacrine; Quinine; Quinolines; Sulfadiazine; Thiosemicarbazones | 1968 |
Effects of chloroquine, quinine, and cycloguanil upon the maturation of asexual erythrocytic forms of two strains of Plasmodium falciparum in vitro.
Topics: Chloroquine; Culture Techniques; Erythrocytes; Humans; Malaria; Male; Methods; Plasmodium falciparum; Proguanil; Quinine | 1968 |
Oliguric renal failure in blackwater fever.
Topics: Acute Kidney Injury; Adolescent; Adult; Anuria; Biopsy; Black People; Chloroquine; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Kidney; Kidneys, Artificial; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinine; Renal Dialysis; Water-Electrolyte Balance; White People | 1968 |
Chloroquine-pyrimethamine-sulfisoxazole therapy of Plasmodium falciparum malaria. An alternative to quinine.
Topics: Chloroquine; Dapsone; Drug Resistance, Microbial; Fever; Humans; Malaria; Male; Military Medicine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfisoxazole; Vietnam | 1969 |
Malaria--a persistent threat.
Topics: Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Military Medicine; Mosquito Control; Plasmodium falciparum; Quinine; United States | 1969 |
A clinical view of the biology of Plasmodia.
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine | 1969 |
Acute falciparum malaria. Field experience with quinine-pyrimethamine combined therapy.
Topics: Chloroquine; Humans; Malaria; Military Medicine; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine; Vietnam | 1969 |
Response to drugs of South American strains of Plasmodium falciparum.
Topics: Chloroquine; Drug Resistance, Microbial; Drug Synergism; Fever; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; South America; Sulfadiazine; Sulfadimethoxine; Sulfamethoxypyridazine; Sulfonamides | 1968 |
Combined pyrimethamine-quinine therapy for chloroquine-resistant P. falciparum infections.
Topics: Adolescent; Adult; Agranulocytosis; Anemia, Hemolytic; Chloroquine; Clinical Laboratory Techniques; Drug Resistance, Microbial; Fever; Humans; Iron; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Scrub Typhus; Sulfadiazine; Thrombocytopenia; Vietnam | 1969 |
Malaria in American soldiers.
Topics: Anemia, Hemolytic; Blood Cell Count; Carrier State; Chloroquine; Hematocrit; Hemoglobinometry; Hepatitis; Humans; Intestinal Diseases, Parasitic; Leukopenia; Malaria; Military Medicine; Plasmodium falciparum; Plasmodium vivax; Primaquine; Quinine; Rupture, Spontaneous; Splenic Rupture; Thrombocytopenia; United States; Vietnam | 1969 |
Studies concerning the mechanism of action of antimalarial drugs. Inhibition of the incorporation of adenosine-8-3H into nucleic acids of Plasmodium berghei.
Topics: Animals; Antimalarials; Autoradiography; Chloroquine; DNA Nucleotidyltransferases; DNA Replication; Escherichia coli; Male; Methods; Nucleosides; Phenanthridines; Plasmodium; Quinacrine; Quinine; Rats; RNA; RNA Nucleotidyltransferases; Time Factors; Tritium | 1969 |
Fatal transfusion malaria.
Topics: Blood Volume; Chloroquine; Chorea; Dehydration; Dexamethasone; Humans; Malaria; Male; Middle Aged; Neurologic Manifestations; Plasmodium falciparum; Pulmonary Edema; Pyrimethamine; Quinine; Transfusion Reaction | 1969 |
Vietnam malaria. Clinical experience with 50 patients.
Topics: Adult; Chloroquine; Humans; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Primaquine; Quinine; Sulfadiazine; United States; Vietnam | 1970 |
Fatal pulmonary edema as a complication of acute falciparum malaria.
Topics: Adolescent; Adult; Cephalosporins; Chloroquine; Digitalis Glycosides; Humans; Hypersensitivity; Malaria; Male; Meperidine; Morphine; Penicillins; Plasmodium falciparum; Pulmonary Edema; Pyrimethamine; Quinine; Radiography; Sulfisoxazole; Vietnam | 1970 |
Response of Laotian malaria strains to chemotherapy.
Topics: Adult; Antimalarials; Asian People; Chloroquine; Drug Resistance, Microbial; Humans; Japan; Laos; Malaria; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfamethoxypyridazine; Sulfonamides; Thailand; Time Factors | 1970 |
The problems of drug-resistant pathogenic bacteria. Elimination of bacterial episomes by DNA-complexing compounds.
Topics: Acridines; Carbon Isotopes; Centrifugation, Density Gradient; Cesium; Chloramphenicol; Chlorides; Chloroquine; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Kanamycin; Lactose; Methylene Blue; Phenanthridines; Quinacrine; Quinine; Rosaniline Dyes; Spermine; Thymidine | 1971 |
Curative and suppressive treatment of P. falciparum malaria with oral and parenteral Fansidar.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Synergism; Female; Humans; Infant; Injections, Intramuscular; Malaria; Mozambique; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Quinine; Sulfadoxine; Sulfonamides | 1971 |
Effects of tetracycline against chloroquine-resistant and chloroquine-sensitive Plasmodium falciparum.
Topics: Administration, Oral; Body Temperature; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Quinine; Recurrence; Tetracycline; Time Factors | 1971 |
Acquired decrease in sensitivity to quinine observed during studies with a strain of chloroquine-resistant Plasmodium falciparum.
Topics: Adult; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Recurrence; Sulfadiazine; Time Factors | 1967 |
The routine treatment of malaria.
Topics: Acute Disease; Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Chronic Disease; Drug Resistance, Microbial; Female; Humans; Infant; Malaria; Male; Plasmodium falciparum; Quinacrine; Quinine; Sulfonamides | 1971 |
The influence of methylene blue on the pentose phosphate pathway in erythrocytes of monkeys infected with Plasmodium knowlesi.
Topics: Animals; Carbon Isotopes; Chloroquine; DNA; Erythrocytes; Glucose; Haplorhini; Isoleucine; Malaria; Methylene Blue; Orotic Acid; Pentosephosphates; Plasmodium; Protein Biosynthesis; Quinacrine; Quinine; RNA; Tritium | 1969 |
Uptake of chloroquine-3-H3 by plasmodium knowlesi in vitro.
Topics: Albumins; Animals; Chloroquine; Cyanates; Dinitrophenols; Erythrocytes; Fluorides; Glucose; Haplorhini; In Vitro Techniques; Iodoacetates; Lysosomes; Malaria; Pinocytosis; Plasmodium; Quinacrine; Quinine; Temperature; Time Factors; Tritium | 1969 |
Effects of quinine and of chloroquine in vitro against a strain of chloroquine-resistant Plasmodium falciparum that displays a relative resistance to quinine in vivo.
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Malaysia; Male; Plasmodium falciparum; Quinine | 1969 |
[Chemotherapeutic activity of standard antimalarials in a simplified test for Plasmodium vinckey infection in the NMPI mouse].
Topics: Animals; Antimalarials; Chloroquine; Long-Term Care; Malaria; Mice; Plasmodium; Primaquine; Pyrimethamine; Quinacrine; Quinine; Sulfadiazine; Sulfonamides; Time Factors | 1970 |
Observations on the relapse activity of Plasmodium fieldi in the rhesus monkey.
Topics: Aedes; Animals; Chloroquine; Chronic Disease; Disease Models, Animal; Haplorhini; Insect Vectors; Malaria; Monkey Diseases; Plasmodium; Quinine; Species Specificity; Time Factors | 1971 |
Action of some antimalaria compounds against Plasmodium berghei in vitro.
Topics: Animals; Antimalarials; Chloroquine; Haplorhini; Leucine; Plasmodium; Primaquine; Proguanil; Pyrimethamine; Quinine; Triazines; Tritium | 1971 |
Quinine: effect of Tetrahymena pyriformis. 3. Energetics of isolated mitochondria in the presence of quinine and other antimalarial drugs.
Topics: Chloroquine; Citrates; Citric Acid Cycle; Depression, Chemical; Fumarates; Glutamates; Hydroxybutyrates; Isocitrates; Ketoglutaric Acids; Malates; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Primaquine; Quinacrine; Quinine; Stimulation, Chemical; Succinates; Tetrahymena pyriformis; Uncoupling Agents | 1971 |
[Causal preventive activity of standard antimalarials in rodent malaria (Plasmodium berghei yoelii)].
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Malaria; Mice; Mice, Inbred Strains; Plasmodium; Primaquine; Pyrimethamine; Quinine; Rodent Diseases; Sulfadiazine | 1972 |
Tetracyclines for malaria.
Topics: Chloroquine; Drug Combinations; Humans; Malaria; Quinine; Tetracycline | 1972 |
[Clinical aspects of G 6 PD deficiency in African children (apropos of 50 cases in Dakars)].
Topics: Adolescent; Anemia, Hemolytic; Child; Child, Preschool; Chloramphenicol; Chloroquine; Erythrocyte Count; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Hemolysis; Humans; Infant; Male; Methods; Quinine; Senegal; Sulfonamides | 1971 |
Studies concerning the mechanism of action of antimalarial drugs. II. Inhibition of the incorporation of adenosine-5'-monophosphate- 3 H into nucleic acids of erythrocyte-free malarial parasites.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Amodiaquine; Animals; Antimalarials; Chloroquine; DNA; Erythrocytes; Methods; Naphthalenes; Phenanthridines; Plasmodium; Proguanil; Quinacrine; Quinine; Rats; RNA; Saponins; Triazines; Trimethoprim; Tritium | 1971 |
Relapse activity in sporozoite-induced infections with a West African strain of Plasmodium ovale.
Topics: Africa, Western; Anopheles; Chloroquine; Humans; Malaria; Male; Plasmodium; Quinine; Recurrence; Time Factors; United States | 1971 |
[Hexamitiasis in two hen turkey flocks].
Topics: Animals; Antiprotozoal Agents; Chloroquine; Disease Outbreaks; Eukaryota; Female; Germany, East; Poultry Diseases; Protozoan Infections; Protozoan Infections, Animal; Quinine; Turkeys | 1971 |
[Effects of quinine, chloroquine, iodoacetate and chlordiazepoxide on the ERG of the isolated rabbit retina].
Topics: Animals; Antimalarials; Chlordiazepoxide; Chloroquine; Electroretinography; Injections; Iodoacetates; Quinine; Rabbits; Retina; Vitreous Body | 1968 |
[Direct and indirect influencing of the ERG through antimalarials].
Topics: Animals; Antimalarials; Blood Pressure; Cats; Chloroquine; Electrocardiography; Electroretinography; Injections, Intra-Arterial; Quinine; Retina | 1968 |
The therapy of cerebral malaria in children. Editorial comment.
Topics: Blood; Brain Diseases; Child; Child, Preschool; Chloroquine; Female; Humans; Malaria; Male; Plasmodium falciparum; Quinine; Tropical Medicine | 1966 |
Reactions of quinine, chloroquine, and quinacrine with DNA and their effects on the DNA and RNA polymerase reactions.
Topics: Chemical Phenomena; Chemistry; Chloroquine; DNA; Escherichia coli; Nucleotidyltransferases; Quinacrine; Quinine; Spermine | 1966 |
[Natural and acquired resistance to malaria: a model case].
Topics: Chloroquine; Fluorescent Antibody Technique; Glucosephosphate Dehydrogenase Deficiency; Humans; Immunity; Immunoglobulin G; Malaria; Oxidative Phosphorylation; Quinine | 1967 |
Management of chloroquine-resistant falciparum malaria.
Topics: Asia, Southeastern; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Military Medicine; Plasmodium falciparum; Quinine; Sulfates; United States; Vietnam; White People | 1967 |
Management of chloroquine resistant falciparum malaria.
Topics: Adult; Brain Diseases; Chloroquine; Dapsone; Dexamethasone; Drug Resistance, Microbial; Edema; Humans; Malaria; Male; Military Medicine; Plasmodium falciparum; Pyrimethamine; Quinine; Tropical Medicine; United States; Vietnam | 1967 |
Imported falciparum malaria with inadequate response to chloroquine.
Topics: Adult; Ambulatory Care; Chloroquine; Communicable Disease Control; Humans; Japan; Malaria; Male; Plasmodium falciparum; Primaquine; Quinine; Thailand | 1966 |
Accidental poisoning in children in Uganda.
Topics: Amitriptyline; Aspirin; Barbiturates; Child; Child, Preschool; Chloroquine; Codeine; Dapsone; Diazepam; Ethanol; Female; Humans; Infant; Iron; Kerosene; Male; Pesticides; Poisoning; Quinine; Tetrachloroethylene; Uganda | 1969 |
Inhibition of lipolytic processes in rat adipose tissue by antimalaria drugs.
Topics: Adipose Tissue; Animals; Antimalarials; Chloroquine; Epididymis; Fatty Acids; Heparin; Hydroxychloroquine; Lipid Metabolism; Male; Primaquine; Quinacrine; Quinidine; Quinine; Rats | 1969 |
[Symptomatology, diagnosis and therapy of malaria].
Topics: Chloroquine; Diagnosis, Differential; Erythrocytes; Humans; Malaria; Plasmodium; Primaquine; Quinine | 1969 |
An automated method of mass drug testing applied to screening for antimalarial activity.
Topics: Animals; Antimalarials; Automation; Chloroquine; Erythrocytes; Glucose; Glycolysis; Lactates; Male; Methods; Neoplasms, Experimental; Pharmacology; Plasmodium; Primaquine; Pyrimethamine; Quinacrine; Quinine; Rats; Sulfadiazine; Sulfones | 1970 |
A unique antinucleic acid approach to the mass screening of antimalarial drugs.
Topics: Animals; Antimalarials; Cell Membrane; Chemical Phenomena; Chemistry; Chloroquine; Computers; DNA, Bacterial; Erythrocytes; Hydrogen-Ion Concentration; Nucleosides; Pharmacology; Plasmodium; Primaquine; Pyrimethamine; Quinacrine; Quinine; Rats; RNA, Bacterial; Sulfones; Temperature; Tritium | 1970 |
Synthesis of potential antimalarials: primaquine analogs.
Topics: Animals; Antimalarials; Chemical Phenomena; Chemistry; Chickens; Chloroquine; Chromatography, Thin Layer; Infrared Rays; Methods; Mice; Primaquine; Quinine; Quinolines; Spectrophotometry | 1970 |
Influence of sucrose on chloroquine-3-H3 content of mammalian cells in vitro: the possible role of lysosomes in chloroquine resistance.
Topics: Animals; Carbon Isotopes; Cell Line; Chloroquine; Cold Temperature; Cricetinae; Culture Techniques; Drug Resistance, Microbial; HeLa Cells; Hexoses; Hydrogen-Ion Concentration; Kidney; Lysosomes; Pinocytosis; Plasmodium; Primaquine; Quinacrine; Quinine; Sucrose; Tritium | 1970 |
Antimalarials: effects on in vivo and in vitro protein synthesis.
Topics: Amino Acids; Antimalarials; Carbon Isotopes; Cell-Free System; Chloroquine; Cycloheximide; Primaquine; Protein Biosynthesis; Quinacrine; Quinine; Tetrahymena | 1970 |
The chemotherapy of rodent malaria. IX. Causal prophylaxis. I. A method for demonstrating drug action on exo-erythrocytic stages.
Topics: Animals; Antimalarials; Chloroquine; Dapsone; Malaria; Male; Mice; Plasmodium; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfadiazine; Triazines | 1970 |
Cerebral malaria.
Topics: Adult; Brain Diseases; Chloroquine; Drug Resistance, Microbial; Female; Humans; Malaria; Male; Quinine | 1970 |
Influence of some antiarrhythmic agents on electrically induced convulsive seizures in rats.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Chloroquine; Electroshock; Female; Lidocaine; Male; Phenytoin; Procainamide; Procaine; Quinidine; Quinine; Rats; Seizures; Time Factors; Water | 1970 |
Methaemoglobin levels in soldiers receiving antimalarial drugs.
Topics: Antimalarials; Australia; Chloroquine; Dapsone; Erythrocyte Count; Humans; Methemoglobin; Military Personnel; Primaquine; Pyrimethamine; Quinine; Reticulocytes; Vietnam | 1971 |
Resistance to primaquine in Plasmodium gallinaceum, and the problem of resistance to quinoline compounds in malaria parasites.
Topics: Aedes; Animals; Chickens; Chloroquine; Drug Resistance, Microbial; Malaria, Avian; Primaquine; Quinacrine; Quinine; Quinolines | 1967 |
[Further development of the Roehl test for testing antimalarial agents on Plasmodium cathemerium in the canary by intravenous administration].
Topics: Animals; Animals, Laboratory; Antimalarials; Canaries; Chloroquine; Injections, Intravenous; Malaria, Avian; Methods; Primaquine; Proguanil; Pyrimethamine; Quinine; Sulfadiazine; Sulfanilamides; Sulfonamides | 1967 |
[Cardiac complications in acute poisoning].
Topics: Adolescent; Adult; Amitriptyline; Arrhythmias, Cardiac; Child; Child, Preschool; Chloroquine; Digitalis Glycosides; Electrocardiography; Heart; Humans; Imipramine; Middle Aged; Poisoning; Quinine | 1967 |
[The effect of lipolytic activity inhibitors on the development of experimental cholesterol atherosclerosis in rabbits].
Topics: Animals; Arteriosclerosis; Chinchilla; Chloroquine; Cholesterol; Diet, Atherogenic; Fibrinolytic Agents; Lipid Metabolism; Liver; Male; Quinine; Rabbits | 1967 |
Falciparum malaria in the United States. Report of a case in a South Viet Nam veteran.
Topics: Adult; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Military Personnel; Plasmodium falciparum; Quinine; United States; Vietnam | 1967 |
Chloroquine-resistant falciparum malaria.
Topics: Chloroquine; Humans; Injections, Intramuscular; Injections, Intravenous; Malaria; Quinine | 1967 |
Chloroquine-resistant falciparum malaria.
Topics: Chloroquine; Humans; Malaria; Military Medicine; Pyrimethamine; Quinine; Vietnam | 1967 |
Treatment of malaria.
Topics: Antimalarials; Chloroquine; Humans; Malaria; Military Medicine; Quinine; Tropical Medicine; Vietnam | 1968 |
[Malaria therapy: quinine again in style].
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; History, 19th Century; History, 20th Century; Humans; Malaria; Mice; Plasmodium; Quinine; Sulfonamides | 1968 |
The lethal effect of certain antimalarial drugs on Tetrahymena pyriformis.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Chloroquine; Chlortetracycline; Metronidazole; Nitrofurantoin; Penicillins; Primaquine; Proguanil; Quinacrine; Quinine; Streptomycin; Sulfadiazine; Sulfisoxazole; Tetrahymena | 1968 |
Chemotherapeutic nitroheterocycles. Nitropyrrole-2-carboxaldehyde derivatives.
Topics: Aldehydes; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Bacteria; Chloroquine; Elements; Fungi; Mice; Pyrroles; Quinine | 1968 |
[On quinine poisoning of the retina. With a remark on experimental chloroquine poisoning].
Topics: Adolescent; Adult; Animals; Blindness; Cats; Chloroquine; Color Perception; Electroretinography; Female; Fundus Oculi; Hearing Disorders; Humans; Optic Nerve; Quinine; Rabbits; Retina; Retinal Hemorrhage; Retinal Pigments; Retinal Vessels; Suicide | 1968 |
[Electroretinographic studies on the development of quinine and resochin retinopathies].
Topics: Animals; Chloroquine; Electroretinography; Eye Diseases; Injections, Intravenous; Quinine; Rabbits; Retina | 1968 |
Characteristics and cross-resistance patterns of chloroquine-resistant Plasmodium berghei infections in mice.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Female; Hematocrit; Isoenzymes; L-Lactate Dehydrogenase; Malaria; Mice; Organ Size; Plasmodium; Primaquine; Pyrimethamine; Quinacrine; Quinine; Rodent Diseases; Serum Albumin; Serum Globulins; Spleen; Splenomegaly; Sulfadiazine | 1968 |
Causal prophylactic effect of Menoctone (a new hydroxynaphthoquinone) against sporozoite-induced Plasmodium berghei infection in mice.
Topics: Animals; Antimalarials; Chloroquine; Cricetinae; Malaria; Mice; Naphthoquinones; Plasmodium; Primaquine; Quinine | 1968 |
Selection of strains of Plasmodium berghei resistant to quinine, chloroquine, and pyrimethamine.
Topics: Animals; Chloroquine; Mice; Pigmentation; Plasmodium; Pyrimethamine; Quinine | 1965 |
[On clinical features, etiology and treatment of acute lupus erythematosus].
Topics: Adolescent; Adult; Aged; Animals; Anti-Bacterial Agents; Blood Transfusion; Child; Chloroquine; Female; Guinea Pigs; Humans; Hydralazine; Lupus Erythematosus, Discoid; Male; Middle Aged; Quinine; Vitamins | 1965 |
[Standardization of chemotherapy of rodent malaria (Plasmodium berghei) on NMRI mice].
Topics: Animals; Body Temperature; Body Weight; Chloroquine; Injections, Intraperitoneal; Malaria; Mice; Quinine; Sulfanilamides | 1965 |
Investigations of the possible relation of ferrihemic acid to drug resistance in Plasmodium berghei.
Topics: Chloroquine; Drug Antagonism; Drug Resistance, Microbial; Heme; Oxygen Consumption; Plasmodium; Quinine; Spectrophotometry | 1966 |
Chloroquine: physiological basis of drug resistance in Plasmodium berghei.
Topics: Animals; Carbon Isotopes; Chloroquine; Drug Resistance, Microbial; Erythrocytes; In Vitro Techniques; Liver; Malaria; Male; Mice; Plasmodium; Quinacrine; Quinine; Radiometry; Spleen | 1966 |
Drug responses of mepacrine- and primaquine-resistant strains of Plasmodium berghei Vincke and Lips, 1948.
Topics: Animals; Antimalarials; Chloroquine; Dapsone; Mice; Plasmodium; Primaquine; Pyrimethamine; Quinine; Sulfadiazine | 1966 |
Comparison of the effects of several drugs on tissue uptake of labeled thyroxine and triiodothyronine in the presence of rat plasma in vitro.
Topics: Animals; Chloroquine; Coloring Agents; Dinitrophenols; In Vitro Techniques; Isoniazid; Liver; Methylene Blue; Muscles; Novobiocin; Pituitary Gland; Quinine; Rats; Rose Bengal; Salicylates; Surface-Active Agents; Thyroxine; Triiodothyronine; Trypan Blue | 1966 |
Treatment of chloroquine-resistant Plasmodium falciparum infections in Vietnam.
Topics: Chloroquine; Dapsone; Humans; Malaria; Military Medicine; Pyrimethamine; Quinacrine; Quinine; Sulfadiazine; Sulfonamides; Vietnam | 1967 |
Hückel molecular orbital calculations for some antimalarial drugs and related molecules.
Topics: Antimalarials; Chemical Phenomena; Chemistry, Physical; Chloroquine; DNA; Primaquine; Pyrimethamine; Quinacrine; Quinine; RNA | 1967 |
Chemotherapy of sporozoite- and blood-induced Plasmodium berghei infections with selected antimalarial agents.
Topics: Animals; Chloroquine; Cricetinae; Dapsone; Malaria; Mice; Primaquine; Pyrimethamine; Quinine; Rats | 1967 |
An outbreak of malaria on shipboard.
Topics: Adolescent; Adult; Chloroquine; Female; Humans; Malaria; Male; Middle Aged; Quinine; Ships | 1967 |
Carbon dioxide fixation in plasmodia and the effect of some antimalarial drugs on the enzyme.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cell-Free System; Chloroquine; Depression, Chemical; Kinetics; Magnesium; Mice; Plasmodium; Quinine; Spectrophotometry; Spermine; Ultrasonics | 1967 |
An analysis of the inhibitory effects of quinine and mepacrine in the guinea-pig isolated ileum.
Topics: Animals; Chloroquine; Depression, Chemical; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Prostaglandin Antagonists; Prostaglandins E; Quinacrine; Quinine | 1980 |
Quinine in chloroquine-resistant falciparum malaria.
Topics: Chloroquine; Humans; Malaria; Plasmodium falciparum; Quinine; Tissue Distribution | 1983 |
Interactions of hemin, antimalarial drugs and hemin-antimalarial complexes with phospholipid monolayers.
Topics: Animals; Antimalarials; Cattle; Chloroquine; Heme; Hemin; Mathematics; Mefloquine; Membranes, Artificial; Phospholipids; Quinine; Quinolines; Surface Properties | 1984 |
The effect of anti-malarial drugs on human natural killer cells in vitro.
Topics: Antimalarials; Cell Line; Chloroquine; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Leukemia, Myeloid, Acute; Mefloquine; Primaquine; Pyrimethamine; Quinacrine; Quinine; Quinolines | 1984 |
Toxicity and side-effects of antimalarials in Africa: a critical review.
Topics: Africa; Aminoquinolines; Antimalarials; Cardiovascular Diseases; Chloroquine; Dapsone; Eye Diseases; Humans; Labyrinth Diseases; Movement Disorders; Neuromuscular Diseases; Pyrimethamine; Quinine; Sulfadoxine | 1984 |
[Falciparum malaria in East African tourists in spite of fansidar prevention. A contribution on increased chloroquine and pyrimethamine-sulfadoxine resistance in areas of East Africa].
Topics: Adult; Africa, Eastern; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Erythrocytes; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1983 |
[Drug-resistant malaria in East Africa].
Topics: Adult; Africa, Eastern; Aged; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1983 |
Lack of cross-resistance to 4-aminoquinolines in chloroquine-resistant Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Plasmodium falciparum; Quinine; Structure-Activity Relationship | 1983 |
In vitro study of drug sensitivity of Plasmodium falciparum: evaluation of a new semi-micro test.
Topics: Antimalarials; Chloroquine; Evaluation Studies as Topic; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Quinolines | 1983 |
Susceptibility of Plasmodium falciparum to five drugs: an in vitro study of isolates mainly from Thailand.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Thailand | 1983 |
Plasmodium falciparum: drug sensitivity in vitro of isolates before and after adaptation to continuous culture.
Topics: Adaptation, Physiological; Animals; Antimalarials; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1983 |
The management of cerebral malaria in African children.
Topics: Africa; Brain Diseases; Child, Preschool; Chloroquine; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Malaria; Male; Plasmodium falciparum; Quinine | 1983 |
Clinical management of acute falciparum malaria in Tanzania.
Topics: Acute Disease; Administration, Oral; Adult; Antimalarials; Child; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Humans; Infusions, Parenteral; Malaria; Plasmodium falciparum; Quinine; Tanzania | 1983 |
Interaction of antimalarial drugs with hemin.
Topics: Animals; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Circular Dichroism; Heme; Hemin; Plasmodium berghei; Quinidine; Quinine; Spectrometry, Fluorescence; Spectrum Analysis | 1983 |
The treatment of falciparum malaria.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinidine; Quinine; Quinolines; Sesquiterpenes | 1984 |
[Chloroquine and pyrimethamine/sulfadoxine resistant malaria tropica in a child with diabetes mellitus].
Topics: Adolescent; Chloroquine; Diabetes Mellitus, Type 1; Diagnosis, Differential; Doxycycline; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfanilamides | 1984 |
Probable chloroquine-resistant Plasmodium falciparum malaria in south-western Africa.
Topics: Adult; Africa, Southern; Africa, Western; Animals; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Tetracycline | 1984 |
The relationship between the in vitro response of Plasmodium falciparum to chloroquine, quinine and mefloquine.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1984 |
Application of an in vitro semi-microtest to the study of drug sensitivity of 66 Plasmodium falciparum isolates from 15 countries.
Topics: Animals; Chloroquine; Drug Resistance, Microbial; Mefloquine; Microbial Sensitivity Tests; Piperazines; Plasmodium falciparum; Quinine; Quinolines | 1984 |
[In vitro sensitivity tests of Plasmodium falciparum samples of the Amazonian Basin (Brazil)].
Topics: Amodiaquine; Animals; Antimalarials; Brazil; Chloroquine; In Vitro Techniques; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines | 1983 |
[Treatment of malaria. Update].
Topics: Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfadoxine | 1984 |
[Drug sensitivity of Plasmodium falciparum in Madagascar. V. Study of the in vitro activity of quinine, mefloquine and halofantrine].
Topics: Antimalarials; Chloroquine; Humans; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Quinolines | 1984 |
Chloroquine resistant Plasmodium falciparum malaria in a local Kenyan: a case report.
Topics: Adult; Chloroquine; Drug Resistance, Microbial; Humans; Kenya; Malaria; Male; Plasmodium falciparum; Quinine | 1984 |
Management of Plasmodium falciparum malaria.
Topics: Amodiaquine; Anemia; Antimalarials; Brain Diseases; Chloroquine; Drug Resistance; Female; Humans; Hypoglycemia; Malaria; Oliguria; Pregnancy; Pregnancy Complications, Infectious; Pulmonary Edema; Pyrimethamine; Quinine; Sulfadoxine | 1984 |
Diverse membrane-active agents modify the hemolytic response to ferriprotoporphyrin IX.
Topics: Adult; Antimalarials; Calcium; Chloroquine; Drug Synergism; Erythrocytes; Female; Heme; Hemin; Hemolysis; Humans; Male; Mefloquine; Osmotic Fragility; Quinine; Quinolines; Sodium Chloride | 1983 |
Effects of antimalarial drugs on human natural killer cell activity.
Topics: Antimalarials; B-Lymphocytes; Chloroquine; Humans; Killer Cells, Natural; Lymphocytes; Lymphocytes, Null; Malaria; Potassium; Pyrimethamine; Quinine; Sodium; T-Lymphocytes | 1983 |
Effect of drug pretreatment on the metabolic oxidation of chlorpromazine in rat.
Topics: Animals; Anthracenes; Chloroquine; Chlorpromazine; Ethanol; Female; Male; Metyrapone; Oxidation-Reduction; Pentobarbital; Premedication; Pyridines; Quinine; Rats; Rats, Inbred Strains; Safrole | 1983 |
Effect of antimalarial drugs on human neutrophil chemotaxis in vitro.
Topics: Antimalarials; Chemotaxis, Leukocyte; Chloroquine; Drug Combinations; Humans; Neutrophils; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Tetracycline; Triazines | 1983 |
[Standardisation of the in vitro chemosensitivity test for Plasmodium falciparum ].
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Erythrocytes; Humans; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Quinolines | 1982 |
[Quartan malaria in a 2-year-old girl].
Topics: Child, Preschool; Chloroquine; Drug Resistance, Microbial; Female; Humans; Italy; Malaria; Plasmodium malariae; Quinine | 1982 |
Imported malaria in adults in Auckland.
Topics: Adolescent; Adult; Chloroquine; Drug Resistance, Microbial; Female; Humans; Kenya; Malaria; Male; Middle Aged; New Zealand; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Primaquine; Quinine; Splenomegaly; Time Factors; Travel | 1982 |
[Resistance of Plasmodium falciparum to fansidar, quinine and tetracycline].
Topics: Adolescent; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfanilamides; Tetracycline | 1982 |
Chloroquine and quinine resistant Plasmodium falciparum on the island of Mindoro, Philippines, 1982.
Topics: Chloroquine; Drug Resistance; Humans; Philippines; Plasmodium falciparum; Quinine | 1982 |
Inhibition of the metabolism and motility of human spermatozoa by various alkaloids.
Topics: Antimalarials; Carbon Dioxide; Chloroquine; Emetine; Humans; Lactates; Lactic Acid; Male; Quinacrine; Quinine; Sperm Motility; Spermatozoa | 1982 |
Fatal falciparum malaria and the availability of parenteral antimalarial drugs in hospitals.
Topics: Chloroquine; England; Formularies, Hospital as Topic; Humans; Infusions, Parenteral; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinine | 1982 |
Suppression by phospholipase A2 inhibitors of secretion of catecholamines from isolated adrenal medullary cells by suppression of cellular calcium uptake.
Topics: Acetophenones; Adrenal Medulla; Animals; Calcium; Carbachol; Catecholamines; Cattle; Chloroquine; Dose-Response Relationship, Drug; Phospholipases; Phospholipases A; Phospholipases A2; Quinacrine; Quinine | 1983 |
In vitro response of Plasmodium falciparum in Thailand to antimalarial drugs.
Topics: Amodiaquine; Antimalarials; Cells, Cultured; Chloroquine; Drug Resistance, Microbial; Female; Humans; Male; Plasmodium falciparum; Quinine; Thailand | 1980 |
Malaria in southeast Queensland in 1979.
Topics: Adolescent; Adult; Australia; Child; Child, Preschool; Chloroquine; Dapsone; Female; Humans; Infant; Infant, Newborn; Malaria; Male; Middle Aged; New Guinea; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine; Sulfadoxine; Tinnitus; Vietnam | 1980 |
[Plasmodium falciparum malaria resistant to polychemotherapy. Usefulness of pathogen culture (author's transl)].
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; In Vitro Techniques; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1981 |
An analysis of the relationship of host factors to clinical falciparum malaria by multiple regression techniques.
Topics: Adult; Age Factors; Black People; Body Weight; Chloroquine; Clindamycin; Fever; Humans; Malaria; Male; Plasmodium falciparum; Quinine; Recurrence; Regression Analysis; White People | 1982 |
Drug-resistant malaria in Africa. A case report and review of the problem and treatment.
Topics: Adult; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Tetracycline | 1982 |
The pharmacology of ototoxic drugs.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Chloroquine; Deafness; Diuretics; Ear, Inner; Hair Cells, Auditory; Humans; Kidney; Kinetics; Neuromuscular Junction; Quinine; Salicylates | 1982 |
Congenital malaria: a report of four cases and a review.
Topics: Asia, Southeastern; Chloroquine; Female; Humans; Infant, Newborn; Malaria; Maternal-Fetal Exchange; Pregnancy; Quinine; United States | 1982 |
Ocular findings in human babesiosis (Nantucket fever).
Topics: Adult; Animals; Babesiosis; Chloroquine; Collagen Diseases; Diagnosis, Differential; Female; Humans; Quinine; Retinal Diseases; Splenectomy | 1982 |
Comparative efficacies of quinine and chloroquine as companions to primaquine in a curative drug regimen.
Topics: Animals; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Macaca mulatta; Malaria; Primaquine; Quinine | 1981 |
The effects of calcium ions on the depression of cardiac contractility by chloroquine and quinine.
Topics: Animals; Calcium; Chloroquine; Depression, Chemical; In Vitro Techniques; Myocardial Contraction; Quinine; Turtles | 1981 |
Normal immunological responses in mice treated with chloroquine, quinine and primaquine.
Topics: Animals; Antibody Formation; Chloroquine; Drug Administration Schedule; Immunity, Cellular; Male; Mice; Mice, Inbred BALB C; Primaquine; Quinine | 1981 |
Induction of selective acid hydrolase release from mouse macrophages during exposure to chloroquine and quinine.
Topics: Animals; Chloroquine; Dose-Response Relationship, Drug; Enzyme Induction; Glycoside Hydrolases; Macrophages; Male; Mice; Mice, Inbred BALB C; Quinine; Time Factors | 1981 |
[Contribution to the determination of four antimalarial molecules (chloroquine, quinine, pyrimethamine, sulfadoxime) mixed in biological fluids. I. Spectrophotometry UV (author's transl)].
Topics: Antimalarials; Chloroquine; Pyrimethamine; Quinine; Spectrophotometry, Ultraviolet; Sulfadoxine | 1981 |
Inhibition of hepatitis B virus specific DNA polymerase by intercalating agents.
Topics: Carrier State; Chloroquine; DNA-Directed DNA Polymerase; Ethidium; Hepatitis B; Hepatitis B Antigens; Hepatitis B virus; Humans; Intercalating Agents; Magnesium; Methylene Blue; Nucleic Acid Synthesis Inhibitors; Primaquine; Quinacrine; Quinine | 1980 |
In vitro susceptibility of Plasmodium falciparum to chloroquine, amodiaquine, quinine, mefloquine, and sulfadoxine/pyrimethamine in Equatorial Guinea.
Topics: Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Equatorial Guinea; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Regression Analysis; Sulfadoxine | 1995 |
Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Base Sequence; Biological Transport; Cell Survival; Chloroquine; CHO Cells; Colchicine; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Protozoan; Doxorubicin; Drug Resistance; Female; Gene Expression; Genes, Protozoan; Membrane Proteins; Oligonucleotides, Antisense; Oocytes; Plasmodium falciparum; Primaquine; Protozoan Proteins; Quinine; Restriction Mapping; Verapamil; Vinblastine; Xenopus laevis | 1994 |
Efficacy of a 3-day oral regimen of quinine in an area of northern Nigeria with low-grade resistance of Plasmodium falciparum to chloroquine and sulphadoxine-pyrimethamine.
Topics: Administration, Oral; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple; Humans; Infant; Malaria, Falciparum; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1995 |
Quinine resistant falciparum malaria acquired in east Africa.
Topics: Adult; Africa, Eastern; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetracycline | 1995 |
Drug-resistant Plasmodium falciparum malaria in the eastern Transvaal.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1994 |
High level chloroquine resistance of Plasmodium falciparum in Madras, Tamil Nadu.
Topics: Adult; Animals; Chloroquine; Doxycycline; Drug Resistance; Humans; India; Malaria, Falciparum; Male; Plasmodium falciparum; Quinine | 1994 |
Congenitally acquired chloroquine-resistant P. falciparum malaria in an infant born in the United States.
Topics: Adult; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Pyrimethamine; Quinine; Sulfadoxine; United States | 1995 |
An etiologic study of hemoglobinuria and blackwater fever in the Kivu Mountains, Zaire.
Topics: Adolescent; Adult; Blackwater Fever; Child; Chloroquine; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobinuria; Hemorrhagic Fever with Renal Syndrome; Humans; Leptospirosis; Malaria, Falciparum; Male; Quinine | 1995 |
Combined chloroquine and primaquine resistant Plasmodium vivax malaria in a patient returning from India.
Topics: Adult; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Vivax; Primaquine; Quinine; Recurrence | 1995 |
Hyper parasitaemia due to plasmodium falciparum malaria.
Topics: Animals; Chloroquine; Host-Parasite Interactions; Humans; Infusions, Intravenous; Injections, Intramuscular; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Quinine | 1994 |
Plasmodium falciparum and Plasmodium vivax: lactate dehydrogenase activity and its application for in vitro drug susceptibility assay.
Topics: Animals; Antimalarials; Chloroquine; Colorimetry; Erythrocytes; Humans; L-Lactate Dehydrogenase; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax; Quinine | 1995 |
[In vitro sensitivity of Plasmodium falciparum to mefloquine, quinine, amodiaquine, chloroquine, pyronaridine and sulfadoxine/pyrimethamine in south Yunnan].
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Mefloquine; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1994 |
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Blotting, Southern; Chloroquine; DNA Primers; DNA, Protozoan; Drug Resistance; Gene Amplification; Gene Expression; Genes, Protozoan; Mefloquine; Molecular Sequence Data; Phenanthrenes; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Quinine; RNA, Messenger; Selection, Genetic; Sequence Homology, Nucleic Acid; Sesquiterpenes | 1994 |
Simple and rapid HPLC of quinine, hydroxychloroquine, chloroquine, and desethylchloroquine in serum, whole blood, and filter paper-adsorbed dry blood.
Topics: Adsorption; Chloroquine; Chromatography, High Pressure Liquid; Humans; Hydroxychloroquine; Quinine; Sensitivity and Specificity; Specimen Handling | 1994 |
Ten-year surveillance of drug-resistant malaria in Burkina Faso (1982-1991).
Topics: Adolescent; Animals; Antimalarials; Burkina Faso; Child; Chloroquine; Drug Resistance; Humans; Longitudinal Studies; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Prevalence; Pyrimethamine; Quinine; Retrospective Studies; Sulfadoxine | 1994 |
Management of malaria before and after introduction of a treatment protocol at the Eldoret District Hospital.
Topics: Adult; Altitude; Chloroquine; Clinical Protocols; Decision Trees; Diagnosis, Differential; Drug Costs; Drug Resistance; Drug Utilization; Hospitals, District; Humans; Kenya; Malaria; Practice Patterns, Physicians'; Prospective Studies; Quinine; Retrospective Studies; Severity of Illness Index | 1994 |
Anaemia, iron deficiency and malaria in a rural community in Brazilian Amazon.
Topics: Adolescent; Adult; Anemia, Hemolytic, Autoimmune; Anemia, Hypochromic; Animals; Brazil; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Female; Ferrous Compounds; Hemoglobinometry; Humans; Incidence; Infant; Intestinal Diseases, Parasitic; Malaria; Male; Mebendazole; Plasmodium falciparum; Plasmodium vivax; Population Surveillance; Pregnancy; Primaquine; Quinine; Rural Population | 1994 |
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives.
Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Mefloquine; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Triazines | 1994 |
Vivax malaria resistant to treatment and prophylaxis with chloroquine.
Topics: Adolescent; Adult; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance, Microbial; Humans; Infant; Malaria, Falciparum; Malaria, Vivax; Polymerase Chain Reaction; Quinine | 1993 |
In vitro activity of pyrimethamine, cycloguanil, and other antimalarial drugs against African isolates and clones of Plasmodium falciparum.
Topics: Africa; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Triazines | 1994 |
Photoaffinity labeling of chloroquine-binding proteins in Plasmodium falciparum.
Topics: Affinity Labels; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Carrier Proteins; Chloroquine; Indicators and Reagents; Iodine Radioisotopes; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Protozoan Proteins; Quinine | 1994 |
Poor response to primaquine in two cases of Plasmodium vivax malaria from Guatemala.
Topics: Chloroquine; Drug Resistance; Drug Therapy, Combination; Guatemala; Humans; Malaria, Vivax; Male; Primaquine; Quinine | 1994 |
In vitro responses of P. falciparum parasites to chloroquine, amodiaquine and quinine in two ecological zones in Ghana.
Topics: Amodiaquine; Animals; Child; Chloroquine; Drug Resistance; Ghana; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinine; Rural Population; Urban Population | 1993 |
Efficacy of chloroquine on Plasmodium falciparum transmitted at Amani, eastern Usambara Mountains, north-east Tanzania: an area where malaria has recently become endemic.
Topics: Adolescent; Adult; Amodiaquine; Animals; Child; Child, Preschool; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Female; Follow-Up Studies; Hemoglobins; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Quinine; Regression Analysis; Sickle Cell Trait; Tanzania | 1993 |
[Acute respiratory failure in tropical malaria during pregnancy. Successful treatment using extracorporeal CO2 elimination].
Topics: Acute Disease; Adult; Carbon Dioxide; Cesarean Section; Chloroquine; Drug Therapy, Combination; Extracorporeal Membrane Oxygenation; Female; Humans; Lung; Malaria, Falciparum; Oxygen; Positive-Pressure Respiration; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinine; Respiratory Distress Syndrome; Tomography, X-Ray Computed | 1993 |
Inhibition of Plasmodium falciparum phospholipase A2 by chloroquine, quinine, and arteether.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Erythrocytes; Humans; Hydrogen-Ion Concentration; Phospholipases A; Phospholipases A1; Phospholipases A2; Plasmodium falciparum; Quinine; Sesquiterpenes | 1993 |
Assessment of the response in vivo and in vitro of Plasmodium falciparum to sulphadoxine-pyrimethamine in the malarious areas of Iran.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amodiaquine; Animals; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Iran; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Regression Analysis; Sulfadoxine | 1993 |
A novel pyrrolidonoalkaneamine (WR268954) that modulates chloroquine resistance of Plasmodium falciparum in vitro.
Topics: Animals; Anisoles; Antimalarials; Chloroquine; Drug Resistance; Drug Synergism; Molecular Structure; Plasmodium falciparum; Pyrrolidines; Quinine; Verapamil | 1993 |
In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 1993 |
Malaria: impact of a standardized protocol on inpatient management.
Topics: Chloroquine; Clinical Protocols; Drug Resistance; Hospitalization; Hospitals, District; Humans; Kenya; Malaria; Prospective Studies; Quinine | 1993 |
Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria.
Topics: Animals; Antimalarials; Artemisinins; Cell Differentiation; Chloroquine; Drugs, Chinese Herbal; Hypoxanthine; Hypoxanthines; Lactates; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes | 1993 |
Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Erythrocytes; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Serial Passage; Vacuoles | 1993 |
Interference by antimalarial drugs with the in-vitro production of reactive nitrogen intermediates by murine macrophages.
Topics: Animals; Antimalarials; Cells, Cultured; Chloroquine; Female; Interferon-gamma; Macrophages; Mice; Mice, Inbred BALB C; Nitrites; Nitrogen; Quinine; Reactive Oxygen Species | 1993 |
Simultaneous determination of chloroquine and quinine in human biological fluids by high-performance liquid chromatography.
Topics: Chloroquine; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Indicators and Reagents; Plasma; Quinine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1993 |
In vitro activity of chloroquine and quinine in combination with desferrioxamine against Plasmodium falciparum.
Topics: Animals; Anti-Bacterial Agents; Chloroquine; Deferoxamine; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Plasmodium falciparum; Quinine | 1993 |
Malaria among United States troops in Somalia.
Topics: Anti-Bacterial Agents; Antimalarials; Chemoprevention; Chloroquine; Clothing; Cohort Studies; Doxycycline; Drug Resistance; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Mefloquine; Military Personnel; Population Surveillance; Prospective Studies; Protective Devices; Pyrimethamine; Quinine; Risk Factors; Somalia; Sulfadoxine; Treatment Failure; Treatment Refusal; United States | 1996 |
Effect of pH on in vitro potency of amantadine against Plasmodium falciparum.
Topics: Adamantane; Amantadine; Ammonium Chloride; Animals; Antimalarials; Chloroquine; Culture Media; Dose-Response Relationship, Drug; Drug Resistance; Humans; Hydrogen-Ion Concentration; Mefloquine; Plasmodium falciparum; Quinine | 1996 |
The iron environment in heme and heme-antimalarial complexes of pharmacological interest.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Heme; Hemeproteins; Hemin; Humans; Iron; Malaria; Quinine; Sesquiterpenes; Spectroscopy, Mossbauer | 1996 |
[Diagnostic and prognostic importance of laboratory tests in malaria in airports. Study of six recent cases].
Topics: Adult; Aerospace Medicine; Antimalarials; Chloroquine; Female; France; Humans; Malaria, Falciparum; Male; Microbiological Techniques; Middle Aged; Phenanthrenes; Platelet Count; Prognosis; Quinine | 1996 |
Severe and complicated malaria in KwaZulu-Natal.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Animals; Antimalarials; Child; Chloroquine; Drug Resistance; Female; Humans; Logistic Models; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Retrospective Studies; South Africa | 1996 |
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs.
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes | 1996 |
In vitro drug sensitivity and clinical aspects of Plasmodium falciparum malaria in African children.
Topics: Animals; Child; Child, Preschool; Chloroquine; Congo; Humans; Infant; Malaria, Falciparum; Mefloquine; Parasitemia; Plasmodium falciparum; Quinine | 1995 |
The interaction of the heme-octapeptide, N-acetylmicroperoxidase-8 with antimalarial drugs: solution studies and modeling by molecular mechanics methods.
Topics: Animals; Antimalarials; Binding Sites; Chloroquine; Drug Design; Drug Interactions; Hemeproteins; In Vitro Techniques; Models, Molecular; Molecular Structure; Peptide Fragments; Peroxidases; Quinine; Solutions; Spectrophotometry; Thermodynamics | 1996 |
Chloroquine resistant Plasmodium vivax malaria in India.
Topics: Adolescent; Antimalarials; Chloroquine; Chromatography, High Pressure Liquid; Drug Resistance; Female; Humans; India; Malaria, Vivax; Quinine | 1996 |
Severe falciparum malaria with hyperparasitaemia: management without exchange blood transfusion.
Topics: Adolescent; Animals; Antimalarials; Chloroquine; Female; Fetal Death; Humans; Malaria, Falciparum; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Quinine; Treatment Outcome | 1996 |
In vitro selection of halofantrine resistance in Plasmodium falciparum is not associated with increased expression of Pgh1.
Topics: Animals; Antimalarials; ATP-Binding Cassette Transporters; Biological Transport; Chloroquine; DNA Fingerprinting; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Gene Dosage; Gene Expression; Immunoblotting; Mefloquine; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Selection, Genetic; Sequence Analysis, DNA; Verapamil | 1996 |
High prevalence of chloroquine resistant Plasmodium falciparum infection in Rajasthan epidemic.
Topics: Animals; Antibodies, Protozoan; Antimalarials; Chloroquine; Disease Outbreaks; Drug Resistance, Microbial; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Immunoglobulin M; India; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Seroepidemiologic Studies; Sulfadoxine; Tumor Necrosis Factor-alpha | 1996 |
Chloroquine, quinine and quinidine inhibit calcium release from macrophage intracellular stores by blocking inositol 1,4,5-trisphosphate binding to its receptor.
Topics: Animals; Antimalarials; Calcium; Calcium Channels; Cell Compartmentation; Chloroquine; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Macrophages, Peritoneal; Mice; Protein Binding; Quinidine; Quinine; Receptors, Cytoplasmic and Nuclear | 1997 |
In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes; Vietnam | 1997 |
Selective induction of phase II drug metabolizing enzyme activities by quinolines and isoquinolines.
Topics: Animals; Chloroquine; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Induction; Epoxide Hydrolases; Glucuronosyltransferase; Glutathione Transferase; Isoquinolines; Liver; Male; Microsomes, Liver; NAD(P)H Dehydrogenase (Quinone); Pharmaceutical Preparations; Quinine; Quinolines; Rats; Rats, Sprague-Dawley | 1997 |
Activity of pyronaridine and mepacrine against twelve strains of Plasmodium falciparum in vitro.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Mefloquine; Naphthyridines; Plasmodium falciparum; Quinacrine; Quinine | 1996 |
Plasmodium falciparum chloroquine and quinine sensitivity in asymptomatic and symptomatic children in São Tomé Island.
Topics: Adolescent; Animals; Antimalarials; Atlantic Islands; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Plasmodium falciparum; Quinine | 1997 |
Evaluation of a solid phase red cell adherence technique for platelet antibody screening.
Topics: Antigens, Human Platelet; Autoantibodies; Blood Platelets; Cell Adhesion; Chloroquine; Erythrocytes; Evaluation Studies as Topic; Humans; Integrin beta3; Quinine; Serology; Thrombocytopenia | 1991 |
Chronic cerebral malaria--is there such a clinical entity?
Topics: Antimalarials; Chloroquine; Chronic Disease; Diabetes Complications; Diabetic Coma; Humans; Malaria, Cerebral; Male; Middle Aged; Quinine | 1995 |
Coexistence of enteric fever with malaria.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Brain Diseases; Chloroquine; Ciprofloxacin; Drug Resistance; Humans; Malaria, Falciparum; Quinine; Tetracycline; Typhoid Fever | 1995 |
Modified antimalarial treatment for chloroquin resistant plasmodium falciparum infection.
Topics: Antimalarials; Chloroquine; Drug Resistance; Endemic Diseases; Humans; Malaria, Falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1995 |
World malaria situation in 1994. Part I. Population at risk.
Topics: Adolescent; Adult; Africa; Age Distribution; Antimalarials; Asia; Child; Child, Preschool; Chloroquine; Disease Transmission, Infectious; Drug Resistance, Multiple; Europe; Humans; Incidence; Malaria, Falciparum; Malaria, Vivax; Quinine; Risk Factors; Survival Rate; United States; World Health Organization | 1997 |
Regulation of heme polymerizing activity and the antimalarial action of chloroquine.
Topics: Animals; Antimalarials; Chloroquine; Cycloheximide; Erythrocytes; Hemin; Injections, Intraperitoneal; Male; Mice; Plasmodium berghei; Polymers; Quinine; Transferases | 1997 |
Pfmdr1 Asn1042Asp and Asp1246Tyr polymorphisms, thought to be associated with chloroquine resistance, are present in chloroquine-resistant and -sensitive Brazilian field isolates of Plasmodium falciparum.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Quinine | 1998 |
Resistance of Plasmodium falciparum malaria to amodiaquine, chloroquine and quinine in the Madang Province of Papua New Guinea, 1990-1993.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Case-Control Studies; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Follow-Up Studies; Humans; Infant; Malaria, Cerebral; Malaria, Falciparum; Male; Papua New Guinea; Parasitemia; Plasmodium falciparum; Prevalence; Quinine; Recurrence; Treatment Failure | 1996 |
In vitro activity of artemether against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial drugs.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Erythrocytes; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Senegal; Sesquiterpenes | 1998 |
In vitro sensitivity of Plasmodium falciparum to eight antimalarials in China-Myanmar and China-Lao PDR border areas.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; China; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Laos; Microbial Sensitivity Tests; Myanmar; Naphthyridines; Plasmodium falciparum; Quinine; Sesquiterpenes | 1997 |
A primary malarial infection is composed of a very wide range of genetically diverse but related parasites.
Topics: Africa; Animals; Antimalarials; Biomarkers; Chloroquine; Clone Cells; Culicidae; Drug Resistance; Genetic Variation; Humans; Insect Bites and Stings; Malaria, Falciparum; Mefloquine; Parasitology; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Quinine; Thailand | 1998 |
Follow-up of the susceptibility of Plasmodium falciparum to antimalarials in Gabon.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Follow-Up Studies; Gabon; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes; Sulfadoxine | 1998 |
In vitro sensitivity of Plasmodium falciparum to halofantrine compared with chloroquine, quinine and mefloquine in the region of Bobo-Dioulasso, Burkina Faso (West Africa).
Topics: Animals; Antimalarials; Burkina Faso; Chloroquine; Drug Resistance; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine | 1998 |
Use of antimalarial drugs in Mali: policy versus reality.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Consumer Behavior; Data Collection; Drug Combinations; Drug Utilization; Female; Health Knowledge, Attitudes, Practice; Humans; Interviews as Topic; Malaria; Male; Mali; Medicine, Traditional; Middle Aged; Proguanil; Pyrimethamine; Quinine; Rural Population; Suburban Population; Sulfadoxine | 1998 |
In-vitro activity of pyronaridine and amodiaquine against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial agents.
Topics: Africa; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Naphthyridines; Plasmodium falciparum; Quinine | 1998 |
In vitro susceptibility studies of Malaysian Plasmodium falciparum isolates and clones against schizontocidal drugs.
Topics: Animals; Antimalarials; Chloroquine; Malaysia; Mefloquine; Plasmodium falciparum; Quinine | 1998 |
[Malaria in an urban environment: the case of the city of Rufisque in Senegal].
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Chloroquine; Drug Resistance; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Prevalence; Quinine; Seasons; Senegal; Urban Population | 1997 |
In vitro susceptibility of Gabonese wild isolates of Plasmodium falciparum to artemether, and comparison with chloroquine, quinine, halofantrine and amodiaquine.
Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Gabon; Humans; Infant; Malaria, Falciparum; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 1998 |
In vitro susceptibility of African isolates of Plasmodium falciparum from Gabon to pyronaridine.
Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Gabon; Humans; Infant; Malaria, Falciparum; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Quinine | 1999 |
[The proper use of antimalarial drugs currently available].
Topics: Animals; Antimalarials; Chemoprevention; Chloroquine; Contraindications; Drug Combinations; Drug Resistance; Endemic Diseases; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Travel | 1998 |
[Pulmonary manifestations associated with malaria].
Topics: Adult; Anti-Bacterial Agents; Antimalarials; Bronchitis; Child; Chloroquine; Female; Humans; Infant, Newborn; Lung Diseases; Malaria, Falciparum; Male; Mefloquine; Oxygen Inhalation Therapy; Phenanthrenes; Pleurisy; Pregnancy; Pregnancy Complications, Parasitic; Pulmonary Edema; Quinidine; Quinine; Respiratory Distress Syndrome, Newborn; Travel | 1998 |
A case of fever, confusion and anaemia in a young woman.
Topics: Adult; Anemia; Antimalarials; Chloroquine; Confusion; Drug Therapy, Combination; Female; Fever; Humans; Malaria, Cerebral; Quinine | 1999 |
Plasmodium falciparum: drug-resistant malaria complicating leukemias and lymphomas in children.
Topics: Adolescent; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Infant; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Malaria, Falciparum; Male; Plasmodium falciparum; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimethamine; Quinine; Sulfalene | 1999 |
Plasmodium chabaudi: effect of antimalarial drugs on gametocytogenesis.
Topics: Animals; Antimalarials; Chloroquine; Gametogenesis; Malaria; Male; Mefloquine; Mice; Mice, Inbred C57BL; Plasmodium chabaudi; Pyrimethamine; Quinine | 1999 |
Phenotypic and genotypic characteristics of recently adapted isolates of Plasmodium falciparum from Thailand.
Topics: Animals; Antimalarials; Blotting, Western; Chloroquine; DNA Fingerprinting; DNA, Protozoan; Drug Resistance; Electrophoresis, Agar Gel; Gene Dosage; Genotype; Humans; Malaria, Falciparum; Mefloquine; Penfluridol; Phenanthrenes; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Quinine; Thailand; Verapamil | 1999 |
[Health assessments of a military company stationed on the Maroni River in French Guiana].
Topics: Acclimatization; Animals; Anti-Bacterial Agents; Antimalarials; Chloroquine; Condoms; Crotalid Venoms; Crotalus; Dermatomycoses; Doxycycline; France; French Guiana; Health Education; HIV Infections; Humans; Leishmaniasis, Cutaneous; Malaria, Falciparum; Military Personnel; Phenanthrenes; Quinine; Risk Factors; Sexual Abstinence; Snake Bites; Staphylococcal Skin Infections; Tropical Medicine | 1999 |
The microculture tetrazolium assay (MTA): another colorimetric method of testing Plasmodium falciparum chemosensitivity.
Topics: Animals; Antimalarials; Chloroquine; Colorimetry; Dose-Response Relationship, Drug; Drug Resistance; L-Lactate Dehydrogenase; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetrazolium Salts | 1999 |
Assessment of drug resistance to the malaria parasite in residents of Kampala, Uganda.
Topics: Antimalarials; Chloroquine; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Quinine; Uganda; Urban Health | 1999 |
Quinolines attenuate PAF-induced pulmonary pressor responses and edema formation.
Topics: Airway Resistance; Animals; Aspirin; Benzoquinones; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Chloroquine; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; In Vitro Techniques; Interleukin-6; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Pulmonary Circulation; Pulmonary Edema; Quinidine; Quinine; Quinolines; Rats; Rats, Wistar; Receptors, Thromboxane; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction | 1999 |
Imported malaria: successful treatment of 31 patients in the era of chloroquine resistance.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Male; Middle Aged; Primaquine; Quinine; Retrospective Studies; Sesquiterpenes; Travel | 1999 |
Pseudo-reticulocytosis as a result of malaria parasites.
Topics: Afghanistan; Animals; Autoanalysis; Chloroquine; DNA; DNA, Protozoan; Electronic Data Processing; Erythrocyte Inclusions; Exchange Transfusion, Whole Blood; False Positive Reactions; Fatal Outcome; Female; Gambia; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Plasmodium vivax; Quinine; Reticulocyte Count; Reticulocytes; RNA; RNA, Protozoan; Time Factors | 1999 |
Analysis of mefloquine resistance and amplification of pfmdr1 in multidrug-resistant Plasmodium falciparum isolates from Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Chromosome Mapping; DNA Primers; DNA, Protozoan; Drug Resistance, Multiple; Electrophoresis, Agar Gel; Electrophoresis, Gel, Pulsed-Field; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Quinine; Scintillation Counting; Sequence Analysis, DNA; Thailand | 1999 |
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes | 1999 |
[Chloroquine sensitivity of Plasmodium falciparum at the Gamkalley Clinic and the Nigerian armed forces PMI (Niamey, Niger)].
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Infant; Malaria, Falciparum; Nigeria; Parasitemia; Plasmodium falciparum; Pyrimethamine; Quinine; Recurrence; Sulfadoxine | 1999 |
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum.
Topics: Amino Acid Substitution; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Mefloquine; Mutation; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes; Verapamil | 2000 |
Antibiotics for prophylaxis of Plasmodium falciparum infections: in vitro activity of doxycycline against Senegalese isolates.
Topics: Amodiaquine; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antimalarials; Artemether; Artemisinins; Chloroquine; Doxycycline; Drug Resistance; Erythrocytes; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Scintillation Counting; Senegal; Sesquiterpenes; Statistics, Nonparametric; Triazines | 2000 |
Re: Drug-resistant falciparum malaria with bowel symptoms.
Topics: Abdomen, Acute; Adult; Antimalarials; Chloroquine; Drug Resistance; Humans; Ileal Diseases; Ileum; Intestinal Perforation; Ischemia; Malaria, Falciparum; Male; Quinine | 2000 |
Stereospecificity of antibody: quinine, the optical isomer of quinidine and anti-malarial drug chloroquine do not cross-react with quinidine immunoassays.
Topics: Antibodies; Antimalarials; Chloroquine; Cross Reactions; Humans; Immunoassay; Quinidine; Quinine; Stereoisomerism | 2000 |
Prevention and treatment of malaria in UK travellers.
Topics: Age Factors; Antimalarials; Chloroquine; Contraindications; Doxycycline; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Proguanil; Quinine; Risk Factors; Travel | 2000 |
[Epidemiological, clinical and therapeutic aspects of severe malaria in adults in the infectious disease department of Central University Hospital of Dakar].
Topics: Adolescent; Adult; Aged; Antimalarials; Chloroquine; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Quinine; Senegal; Urban Population | 1999 |
Therapy and drug resistance in malaria.
Topics: Adolescent; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Infant; Malaria; Male; Prospective Studies; Quinine | 2000 |
Chloroquine resistant malaria.
Topics: Africa South of the Sahara; Anti-Bacterial Agents; Antimalarials; Chloroquine; Doxycycline; Drug Antagonism; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Patient Selection; Pyrimethamine; Quinine; Sulfadoxine | 2000 |
Haemozoin formation in the midgut of the blood-sucking insect Rhodnius prolixus.
Topics: Animals; Biological Factors; Chloroquine; Crystallization; Female; Heme; Hemeproteins; Hemolymph; Hot Temperature; Intestinal Mucosa; Intestines; Lipid Peroxidation; Microscopy, Electron; Pigments, Biological; Quinine; Rhodnius; Spectroscopy, Fourier Transform Infrared | 2000 |
In vitro susceptibility of Plasmodium falciparum to four antimalarial drugs in the Central Province of Papua New Guinea.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Mefloquine; Microbial Sensitivity Tests; Papua New Guinea; Phenanthrenes; Plasmodium falciparum; Quinine | 1998 |
Interaction of chloroquine and its analogues with heme: An isothermal titration calorimetric study.
Topics: Amodiaquine; Antimalarials; Binding Sites; Calorimetry; Chloroquine; Hemin; Hydrogen-Ion Concentration; Mefloquine; Octoxynol; Quinidine; Quinine; Solubility; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Titrimetry | 2000 |
Declining chloroquine resistance of Plasmodium falciparum in Lambaréné, Gabon from 1992 to 1998.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Gabon; Humans; In Vitro Techniques; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Practice Guidelines as Topic; Prospective Studies; Quinine | 2001 |
Pulmonary manifestations in malaria.
Topics: Adult; Animals; Antimalarials; Chloroquine; Female; Humans; Lung Diseases; Malaria, Falciparum; Malaria, Vivax; Male; Plasmodium falciparum; Plasmodium vivax; Quinine | 2000 |
Use of the DELI-microtest to determine the drug sensitivity of Plasmodium falciparum in Burkina Faso.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Malaria, Falciparum; Mefloquine; Parasitemia; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Reagent Kits, Diagnostic; Sensitivity and Specificity; Statistics, Nonparametric | 2001 |
Potent antimalarial activities of polyether antibiotic, X-206.
Topics: Actinomycetales; Animals; Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Artesunate; Cell Death; Cell Line; Chloroquine; Drug Resistance; Embryo, Mammalian; Embryo, Nonmammalian; Ethers, Cyclic; Humans; Malaria; Mice; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes | 2001 |
Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum.
Topics: Acridine Orange; Animals; Antimalarials; Calcium Channel Blockers; Chloroquine; Drug Interactions; Drug Resistance; Fluorescence; Membrane Proteins; Membrane Transport Proteins; Molecular Conformation; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinidine; Quinine; Verapamil | 2002 |
Acute acalculous cholecystitis associated with co-infection by Plasmodium falciparum and Plasmodium vivax.
Topics: Animals; Antimalarials; Chloroquine; Cholecystitis; Female; Humans; Malaria; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Quinine | 2002 |
Resistant malaria in a neonate.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant, Newborn; Malaria, Falciparum; Mefloquine; Quinine; Risk Assessment; Sesquiterpenes; Severity of Illness Index; Treatment Outcome | 2002 |
[A collective malarial infestation during a humanitarian mission in west Africa].
Topics: Adult; Altruism; Animals; Antimalarials; Body Weight; Chemoprevention; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Male; Mali; Mauritania; Middle Aged; Morocco; Phenanthrenes; Plasmodium falciparum; Proguanil; Quinine; Travel | 2002 |
Solution structures of antimalarial drug-heme complexes.
Topics: Aminoquinolines; Antimalarials; Binding Sites; Chloroquine; Dimerization; Hemin; Hydrogen-Ion Concentration; Macromolecular Substances; Nuclear Magnetic Resonance, Biomolecular; Protons; Quinidine; Quinine; Solutions; Thermodynamics | 2002 |
[Center of multidrug-resistant malaria in a forest zone of Cameroon revisited after 14 years].
Topics: Amodiaquine; Animals; Cameroon; Chloroquine; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Quinine; Trees | 2002 |
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.
Topics: Alleles; Amodiaquine; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Genes, Protozoan; Haplotypes; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine; Sesquiterpenes; Transfection; Verapamil | 2002 |
Haem polymerase as a novel target of antimalarial action of cyproheptadine.
Topics: Animals; Antimalarials; Chloroquine; Cyproheptadine; Disease Models, Animal; Drug Resistance; Enzyme Inhibitors; Hemeproteins; Mefloquine; Mice; Plasmodium yoelii; Quinine; Transferases; Treatment Outcome | 2002 |
Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand.
Topics: Amodiaquine; Animals; Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Gene Frequency; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Thailand | 2002 |
In vitro activity of chloroquine, quinine, mefloquine and halofantrine against Gabonese isolates of Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Gabon; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine | 2003 |
[Assay of sensitivity of Plasmodium falciparum to chloroquine, amodiaquine, piperaquine, mefloquine and quinine in Yunnan province].
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 1999 |
Profile and evolution of the chemosusceptibility of falciparum malaria imported into France in 2000.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; France; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Proguanil; Quinine; Triazines | 2002 |
In-vitro sensitivity of Plasmodium falciparum to chloroquine, halofantrine, mefloquine and quinine in Madagascar.
Topics: Animals; Antimalarials; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Hospitals, Public; Hospitals, Urban; Humans; Madagascar; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Rural Health | 2002 |
Drug-resistant malaria in Bangladesh: an in vitro assessment.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Bangladesh; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes | 2003 |
In vitro sensitivity of Plasmodium falciparum to amodiaquine compared with other major antimalarials in Madagascar.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Humans; Inhibitory Concentration 50; Madagascar; Malaria, Falciparum; Mefloquine; Parasitemia; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Triazines | 2002 |
Health seeking behavior by families of children suspected to have malaria in Kabale: Uganda.
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Family; Female; Health Facilities; Health Knowledge, Attitudes, Practice; Health Services Accessibility; Humans; Infant; Malaria, Falciparum; Male; Medicine, African Traditional; Patient Acceptance of Health Care; Pyrimethamine; Quinine; Sulfadoxine; Uganda | 2002 |
[Malaria--case report].
Topics: Adult; Anti-Infective Agents; Antidiarrheals; Antimalarials; Chloroquine; Ciprofloxacin; Diarrhea; Emergencies; Fluid Therapy; Glasgow Coma Scale; Humans; Loperamide; Malaria, Cerebral; Malaria, Falciparum; Male; Mefloquine; Nigeria; Parasitemia; Positive-Pressure Respiration; Proguanil; Quinine; Respiratory Distress Syndrome; Travel | 2003 |
Surveillance of in vivo resistance of Plasmodium falciparum to antimalarial drugs from 1992 to 1999 in Malabo (Equatorial Guinea).
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Equatorial Guinea; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 2003 |
[Imported malaria in 2000 in 2 northern Paris hospitals].
Topics: Africa; Antimalarials; Chemoprevention; Chloroquine; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Paris; Quinine; Travel; Treatment Failure | 2003 |
Mapping of the Plasmodium falciparum multidrug resistance gene 5'-upstream region, and evidence of induction of transcript levels by antimalarial drugs in chloroquine sensitive parasites.
Topics: 5' Untranslated Regions; Animals; Antimalarials; ATP-Binding Cassette Transporters; Base Sequence; Chloroquine; Chromosome Mapping; Drug Resistance, Multiple; Gene Expression Regulation; Genes, MDR; Genes, Protozoan; Genes, Reporter; Luciferases; Mefloquine; Molecular Sequence Data; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Nucleic Acid; Transcription, Genetic | 2003 |
Multiple transporters associated with malaria parasite responses to chloroquine and quinine.
Topics: Animals; Antimalarials; Chloroquine; Databases, Nucleic Acid; Drug Resistance; Genes, Protozoan; Humans; Linkage Disequilibrium; Malaria, Falciparum; Membrane Transport Proteins; Molecular Sequence Data; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine | 2003 |
[Case of malaria due to Plasmodium falciparum resistant to quinacrine and to quinine and treated with nivaquine].
Topics: Chloroquine; Humans; Malaria; Plasmodium falciparum; Quinacrine; Quinine | 1952 |
Screening of antimalarials against P. gallinaceum in chicks.
Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Chickens; Chloroquine; Malaria; Proguanil; Quinacrine; Quinine; Sulfadiazine | 1952 |
Effect of parenteral-administration of antimalarials in simian malaria.
Topics: Antimalarials; Arsenicals; Chloroquine; Malaria; Quinine | 1952 |
Therapeutic trials with pyrimethamine (daraprim), resochin, amodiaquin (camoquin) and quinine.
Topics: Amodiaquine; Antimalarials; Chloroquine; Humans; Malaria; Pyrimethamine; Quinine | 1953 |
Potentiation of the curative action of primaquine in vivax malaria by quinine and chloroquine.
Topics: Antimalarials; Chloroquine; Humans; Malaria; Malaria, Vivax; Primaquine; Quinine | 1955 |
Effects of quinine, proguanil and chloroquine on cardio-vascular responses of adrenaline and acetylcholine in dogs.
Topics: Acetylcholine; Animals; Cardiovascular System; Chloroquine; Dogs; Epinephrine; Heart; Humans; Proguanil; Quinine | 1956 |
[Experimental malaria: Plasmodium berghei].
Topics: Chloroquine; Malaria; Plasmodium berghei; Quinacrine; Quinine | 1958 |
Action of quinine, qunidine mepacrine and chloroquine on the skeletal muscle.
Topics: Antimalarials; Chloroquine; Humans; Muscle, Skeletal; Muscles; Quinacrine; Quinine | 1960 |
Reaction between DNA and quinacrine and other antimalarials.
Topics: Antimalarials; Chloroquine; DNA; Quinacrine; Quinidine; Quinine | 1962 |
Studies on the toxicity and action of diaminodiphenyl-sulfone (DDS) in avian and simian malaria.
Topics: Animals; Antimalarials; Birds; Chloroquine; Dapsone; Malaria; Malaria, Avian; Proguanil; Pyrimethamine; Quinine | 1962 |
DRUG RESISTANCE IN PLASMODIUM FALCIPARUM FROM THAILAND.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Humans; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine; Thailand | 1963 |
BLACKWATER FEVER AFTER THE USE OF CHLOROQUINE-PYRIMETHAMINE.
Topics: Blackwater Fever; Chloroquine; Hemolysis; Humans; Malaria; New Guinea; Pyrimethamine; Quinine; Toxicology | 1963 |
PLASMODIUM FALCIPARUM RESISTANT TO CHLOROQUINE IN CAMBODIA.
Topics: Cambodia; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Humans; Plasmodium falciparum; Pyrimethamine; Quinine | 1963 |
ANTIMALARIAL DRUG TRIALS ON A MULTIRESISTANT STRAIN OF PLASMODIUM FALCIPARUM.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Humans; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Thailand | 1963 |
DRUG-RESISTANT FALCIPARUM MALARIA FROM CAMBODIA AND MALAYA.
Topics: Animals; Cambodia; Chloroquine; Culicidae; Drug Resistance; Drug Resistance, Microbial; Humans; Malaria; Malaria, Falciparum; Malaysia; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine | 1963 |
TROPICAL DISEASES OF THE EYE.
Topics: Arsenicals; Arsphenamine; Chlamydia; Chlamydophila psittaci; Chloroquine; Deficiency Diseases; Diagnosis; Hemoglobins; Hemoglobins, Abnormal; Iatrogenic Disease; Ophthalmology; Quinine; Sparganosis; Sulfamethoxypyridazine; Toxicology; Trachoma; Tropical Medicine | 1964 |
FLUORESCENT ANTIBODY STUDIES IN HUMAN MALARIA. II. DEVELOPMENT AND PERSISTENCE OF ANTIBODIES TO PLASMODIUM FALCIPARUM.
Topics: Amodiaquine; Antibodies; Antigen-Antibody Reactions; Chloroquine; Fluorescent Antibody Technique; Humans; Immune Sera; Malaria; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinine; Vaccination | 1964 |
STUDIES ON A STRAIN OF CHLOROQUINE-RESISTANT PLASMODIUM FALCIPARUM FROM THAILAND.
Topics: Amodiaquine; Antimalarials; Asia, Southeastern; Biomedical Research; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Humans; Hydroxychloroquine; Malaria; Malaria, Falciparum; Pharmacology; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine; Thailand | 1964 |
[A PATIENT WITH TROPICAL MALARIA].
Topics: Amodiaquine; Antimalarials; Chloroquine; Dosage Forms; Drug Resistance; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Primaquine; Quinine | 1964 |
[OPHTHALMOLOGICAL COMPLICATIONS OF CERTAIN GENERAL THERAPEUTICS].
Topics: Acetazolamide; Adrenal Cortex Hormones; Anthelmintics; Arsenicals; Barbiturates; Chloroquine; Chlorpromazine; Dinitrophenols; Ophthalmology; Parasympathomimetics; Quinidine; Quinine; Streptomycin; Sulfonamides; Toxicology; Tranquilizing Agents; Vitamin D; Vitamins | 1964 |
DRUG-RESISTANCE IN FALCIPARUM MALARIA IN SOUTH-EAST ASIA.
Topics: Adolescent; Asia, Southeastern; Child; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Humans; Malaria; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine; Statistics as Topic; Toxicology | 1964 |
ANTIHISTAMINIC ACTION OF ANTIMALARIALS.
Topics: Acetylcholine; Animals; Antimalarials; Blood Pressure; Blood Pressure Determination; Capillary Permeability; Chloroquine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Muscle, Smooth; Pharmacology; Quinacrine; Quinine; Research | 1963 |
[THE HEART AND POISONINGS].
Topics: Chloroquine; Diagnosis; Digitalis Glycosides; Heart; Heart Failure; Imipramine; Prognosis; Quinidine; Quinine; Toxicology | 1964 |
UPTAKE OF DYES AND DRUGS BY LIVING CELLS IN CULTURE.
Topics: Acridines; Anthracenes; Carcinogens; Chloroquine; Chlortetracycline; Coloring Agents; Dexamethasone; Fluorescence; Histocytochemistry; Humans; Indoles; Indomethacin; Lysosomes; Metabolism; Microscopy; Microscopy, Fluorescence; Porphyrins; Quinine; Quinolines; Research; Research Design; Stilbamidines; Tissue Culture Techniques; Trypan Blue; Vitamin A | 1964 |
APPARENT REFRACTORINESS TO CHLOROQUINE, PYRIMETHAMINE, AND QUININE IN STRAINS OF PLASMODIUM FALCIPARUM FROM VIETNAM.
Topics: Chloroquine; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Humans; Malaria; Military Medicine; Plasmodium falciparum; Pyrimethamine; Quinine; Vietnam | 1965 |
STUDIES ON A STRAIN OF CHLOROQUINE-RESISTANT PLASMODIUM FALCIPARUM FROM VIET-NAM.
Topics: Amodiaquine; Antimalarials; Biomedical Research; Chloroquine; Drug Therapy; Humans; Malaria; Malaria, Falciparum; Pharmacology; Plasmodium falciparum; Pyrimethamine; Quinine; Statistics as Topic; Vietnam | 1964 |
A PROBLEM IN RESEARCH.
Topics: Antineoplastic Agents; Chloroquine; Electron Transport Complex IV; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Quinine; Rabbits; Rats; Research | 1965 |
QUININE-RESISTANT PLASMODIUM BERGHEI IN MICE.
Topics: Animals; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Malaria; Mice; Pharmacology; Plasmodium berghei; Quinine; Research; Toxicology | 1965 |
CHLOROQUINE-RESISTANT STRAIN OF PLASMODIUM FALCIPARUM FROM KHAO MAI KHAEO, THAILAND.
Topics: Chloroquine; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Humans; Malaria; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Thailand | 1965 |
The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids.
Topics: Animals; Antiprotozoal Agents; Chloroquine; Cinchona Alkaloids; Drug Design; Drug Resistance; Hemeproteins; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Quinine; Stereoisomerism | 2003 |
Multi-drug resistant Plasmodium falciparum malaria in Assam, India: timing of recurrence and anti-malarial drug concentrations in whole blood.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Chloroquine; Drug Resistance, Multiple; Female; Humans; India; Malaria, Falciparum; Male; Plasmodium falciparum; Quinine; Recurrence; Sulfadoxine; Time Factors | 2003 |
Therapeutic efficacies of antimalarial drugs in the treatment of uncomplicated, Plasmodium falciparum malaria in Assam, north-eastern India.
Topics: Adolescent; Adult; Aged; Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; India; Infant; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
A comparison of chloroquine and emetine in the treatment of amoebic liver abscess.
Topics: Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Liver Abscess, Amebic; Quinine | 1951 |
Treatment with antimalarials adversely affects the oxidative energy metabolism in rat liver mitochondria.
Topics: Adenosine Triphosphatases; Animals; Antimalarials; Chloroquine; Cytochromes; Energy Metabolism; Male; Mitochondria, Liver; Oxidative Phosphorylation; Primaquine; Quinine; Rats; Rats, Inbred Strains | 2004 |
Malaria during pregnancy in a reference centre from the Brazilian Amazon: unexpected increase in the frequency of Plasmodium falciparum infections.
Topics: Adolescent; Adult; Antimalarials; Brazil; Child; Chloroquine; Cross-Sectional Studies; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Quinine | 2004 |
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfanilamide; Sulfanilamides; Ultraviolet Rays | 2004 |
Dissecting the loci of low-level quinine resistance in malaria parasites.
Topics: Amino Acid Sequence; Animals; Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Chromosome Mapping; Drug Resistance; Genes, Protozoan; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Multifactorial Inheritance; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quantitative Trait Loci; Quantitative Trait, Heritable; Quinine; Repetitive Sequences, Nucleic Acid; Sodium-Hydrogen Exchangers | 2004 |
Polymorphism of the Plasmodium falciparum multidrug resistance and chloroquine resistance transporter genes and in vitro susceptibility to aminoquinolines in isolates from the Peruvian Amazon.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Genes, MDR; Genotype; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine | 2004 |
Retail supply of malaria-related drugs in rural Tanzania: risks and opportunities.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Antimalarials; Chloroquine; Commerce; Dosage Forms; Health Services Accessibility; Humans; Malaria; Private Sector; Quinine; Rural Health; Tanzania; Trimethoprim, Sulfamethoxazole Drug Combination | 2004 |
Drug resistance in Plasmodium falciparum from the Chittagong Hill Tracts, Bangladesh.
Topics: Adolescent; Adult; Animals; Antimalarials; ATP-Binding Cassette Transporters; Bangladesh; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Genetic Markers; Genotype; Humans; Malaria, Falciparum; Male; Membrane Proteins; Membrane Transport Proteins; Mutation; Parasitemia; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Quinine; Sulfadoxine; Treatment Outcome | 2004 |
The antimalarial drug resistance protein Plasmodium falciparum chloroquine resistance transporter binds chloroquine.
Topics: Animals; Antimalarials; Biological Transport; Cell Membrane; Chloroquine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Kinetics; Membrane Proteins; Membrane Transport Proteins; Mutation; Pichia; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Quinine; Subcellular Fractions; Time Factors | 2004 |
Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts.
Topics: Animals; Antimalarials; Chloroquine; Mefloquine; Molecular Conformation; Molecular Structure; Plasmodium falciparum; Quinine; Structure-Activity Relationship | 2004 |
The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs.
Topics: Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Cycloheximide; Drug Resistance, Multiple, Fungal; Gene Deletion; Genes, Fungal; Mefloquine; Mutation; Quinacrine; Quinidine; Quinine; Saccharomyces cerevisiae; Transcription, Genetic | 2004 |
Chloroquine, proguanil, mepacrine and quinine in the treatment of malaria caused by Plasmodium falciparum.
Topics: Chloroquine; Humans; Malaria; Plasmodium falciparum; Proguanil; Quinacrine; Quinine | 1949 |
Assessment of doctors' management of severe malaria in urban centres in Eastern Nigeria.
Topics: Adult; Analgesics; Analgesics, Non-Narcotic; Anemia; Antimalarials; Blood Transfusion; Chloroquine; Drinking Behavior; Dyspnea; Female; Fever; Hematinics; Histamine H1 Antagonists; Humans; Malaria, Cerebral; Male; Medicine; Nigeria; Practice Patterns, Physicians'; Quinine; Seizures; Specialization; Unconsciousness; Urban Health Services; Vomiting | 2004 |
Structure of the amodiaquine-FPIX mu oxo dimer solution complex at atomic resolution.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Quinidine; Quinine | 2004 |
In vitro monitoring of Plasmodium falciparum susceptibility to artesunate, mefloquine, quinine and chloroquine in Cambodia: 2001-2002.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Statistics, Nonparametric | 2005 |
[Drug susceptibility of Plasmodium falciparum from polyclonal isolates].
Topics: Africa, Western; Alleles; Animals; Antigens, Protozoan; Antimalarials; Cells, Cultured; Chloroquine; DNA, Protozoan; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Evolution, Molecular; France; Gene Amplification; Genotype; Humans; Malaria, Falciparum; Merozoite Surface Protein 1; Minisatellite Repeats; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Genetic; Protozoan Proteins; Quinine | 2004 |
[Imported cerebral malaria].
Topics: Adult; Antimalarials; Chloroquine; Drug Resistance; Female; France; Humans; Malaria, Cerebral; Malaria, Falciparum; Quinine; Senegal; Travel | 2005 |
Chemosensitizing action of cepharanthine against drug-resistant human malaria, Plasmodium falciparum.
Topics: Alkaloids; Animals; Benzylisoquinolines; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Humans; Inhibitory Concentration 50; KB Cells; Malaria, Falciparum; Male; Mice; Parasitemia; Parasitic Sensitivity Tests; Plasmodium berghei; Quinine; Verapamil | 2005 |
ATPase activity of purified plasma membranes and digestive vacuoles from Plasmodium falciparum.
Topics: Adenosine Triphosphatases; Animals; Antimalarials; Artemisinins; Cell Membrane; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Subcellular Fractions; Vacuoles | 2005 |
Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT.
Topics: Acids; Amino Acid Sequence; Animals; Antimalarials; Chloroquine; Cytoplasmic Vesicles; Dictyostelium; Drug Resistance, Bacterial; Gene Expression; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Phenotype; Phylogeny; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinidine; Quinine; Quinolines; Transfection | 2005 |
Simultaneous determination of quinine and chloroquine anti-malarial agents in pharmaceuticals and biological fluids by HPLC and fluorescence detection.
Topics: Antimalarials; Chloroquine; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Quinine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2005 |
Effects of quinine, quinidine, and chloroquine on alpha9alpha10 nicotinic cholinergic receptors.
Topics: Animals; Antimalarials; Chloroquine; Hair Cells, Auditory, Inner; Quinidine; Quinine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Recombinant Proteins; Xenopus laevis | 2005 |
In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Thailand; Time Factors | 2005 |
Economic evaluation of a policy change from single-agent treatment for suspected malaria to artesunate-amodiaquine for microscopically confirmed uncomplicated falciparum malaria in the Oussouye District of south-western Senegal.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Health Care Costs; Health Policy; Humans; Infant; Malaria, Falciparum; Male; Quinine; Rural Health; Senegal; Sesquiterpenes | 2005 |
Antimalarials inhibit human erythrocyte membrane acetylcholinesterase.
Topics: Acetylcholinesterase; Adult; Antimalarials; Chloroquine; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Erythrocyte Membrane; Female; Humans; Kinetics; Male; Middle Aged; Primaquine; Quinine | 2005 |
In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda.
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Multiple; Female; Humans; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Rwanda; Sesquiterpenes | 2006 |
Hepatic dysfunction in a patient with Plasmodium vivax infection.
Topics: Adult; Antimalarials; Chloroquine; Doxycycline; Drug Resistance, Microbial; Drug Therapy, Combination; Erythrocytes; Humans; Liver; Malaria, Vivax; Male; Quinine | 2005 |
In vitro study assessing the response of plasmodium falciparum malaria to chloroquine, sulfadoxine/pyrimethamine, quinine and mefloquine in Wad Medani District, Sudan.
Topics: Animals; Antimalarials; Chloroquine; In Vitro Techniques; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Sudan; Sulfadoxine | 2006 |
Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum.
Topics: Aniline Compounds; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Biological Transport, Active; Cell Membrane Permeability; Chloroquine; Drug Resistance; Erythrocytes; Fluorescent Dyes; Genetic Linkage; In Vitro Techniques; Intracellular Membranes; Lactones; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Sesquiterpenes; Substrate Specificity; Vacuoles; Xanthenes | 2006 |
Use of refractometry and colorimetry as field methods to rapidly assess antimalarial drug quality.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Chromatography, High Pressure Liquid; Colorimetry; Indicators and Reagents; Quality Control; Quinine; Reference Standards; Refractometry; Sesquiterpenes; Spectrophotometry, Ultraviolet; Sulfadoxine | 2007 |
[Successful management of malaria tropica with 50% parasitaemia].
Topics: Animals; Antimalarials; Chloroquine; Female; Germany; Humans; Kenya; Liver Function Tests; Malaria, Falciparum; Middle Aged; Parasitemia; Plasmodium falciparum; Quinine; Travel | 2006 |
Therapeutic efficacy of quinine plus sulfadoxine-pyremethamine for the treatment of uncomplicated falciparum malaria in Bangladesh.
Topics: Adolescent; Adult; Animals; Antimalarials; Bangladesh; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Treatment Failure | 2006 |
Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Quinidine; Quinine | 2007 |
[A plasmodium alciparum malaria case originated from Mozambique: clues for the diagnosis and therapy].
Topics: Animals; Antimalarials; Canada; Chloroquine; Doxycycline; Drug Resistance; Erythrocytes; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Mozambique; Parasitemia; Plasmodium falciparum; Quinine; Secondary Prevention; Travel; Turkey | 2006 |
Very small injected samples to study chloroquine and quinine in human serum using capillary-LC and native fluorescence.
Topics: Antimalarials; Chloroquine; Chromatography, High Pressure Liquid; Fluorescence; Humans; Hydrogen-Ion Concentration; Lasers; Quinine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2007 |
A non-radiolabeled heme-GSH interaction test for the screening of antimalarial compounds.
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Chloroquine; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Glutathione; Heme; Indicators and Reagents; Mefloquine; Methylene Blue; o-Phthalaldehyde; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Spectrometry, Fluorescence | 2007 |
Quality evaluation of chloroquine, quinine, sulfadoxine-pyrimethamine and proguanil formulations sold on the market in East Congo DR.
Topics: Antimalarials; Chloroquine; Chromatography, High Pressure Liquid; Democratic Republic of the Congo; Drug Approval; Drug Combinations; Drug Industry; Pharmaceutical Preparations; Product Surveillance, Postmarketing; Proguanil; Pyrimethamine; Quality Control; Quinine; Sulfadoxine; Tablets | 2007 |
Diagnosis and management of malaria by rural community health providers in the Lao People's Democratic Republic (Laos).
Topics: Administration, Oral; Adult; Antimalarials; Child; Chloroquine; Clinical Competence; Community Health Services; Cross-Sectional Studies; Female; Health Knowledge, Attitudes, Practice; Health Personnel; Hospitalization; Humans; Injections, Intravenous; Laos; Malaria, Falciparum; Male; Pregnancy; Pregnancy Complications, Infectious; Quinine; Rural Health; Severity of Illness Index; Treatment Failure; Volunteers | 2007 |
The antimalarial drugs quinine, chloroquine and mefloquine are antagonists at 5-HT3 receptors.
Topics: Algorithms; Animals; Antimalarials; Binding, Competitive; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Electrophysiology; Female; Granisetron; In Vitro Techniques; Kinetics; Mefloquine; Models, Molecular; Oocytes; Quinine; Radioligand Assay; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Xenopus laevis | 2007 |
Analytical interferences of drugs in the chemical examination of urinary protein.
Topics: Chloroquine; Ciprofloxacin; Clinical Laboratory Techniques; Humans; Pharmaceutical Preparations; Proteinuria; Quinine; Reagent Strips; Reproducibility of Results; Sensitivity and Specificity | 2007 |
The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Infant; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 2007 |
Prevalent pfmdr1 n86y mutant Plasmodium falciparum in Madagascar despite absence of pfcrt mutant strains.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; DNA, Protozoan; Drug Resistance; Humans; Inhibitory Concentration 50; Madagascar; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Protozoan Proteins; Quinine; Rural Population | 2007 |
In vitro antimalarial activity of methylene blue against field isolates of Plasmodium falciparum from children in Southwest Nigeria.
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Male; Methylene Blue; Plasmodium falciparum; Quinine | 2007 |
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Global Health; Half-Life; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2007 |
Extensive genetic diversity in the Plasmodium falciparum Na+/H+ exchanger 1 transporter protein implicated in quinine resistance.
Topics: Amino Acid Sequence; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Gene Frequency; Genetic Variation; Genotype; Geography; India; Molecular Sequence Data; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Quinine; Sequence Homology, Amino Acid; Sodium-Potassium-Chloride Symporters; Sulfadoxine | 2007 |
A simple technique for the detection of anti-malarial drug formulations and their presence in human urine.
Topics: Amodiaquine; Antimalarials; Biological Assay; Biological Availability; Chloroquine; Chromatography, Thin Layer; Fraud; Humans; Malaria; Primaquine; Product Surveillance, Postmarketing; Pyrimethamine; Quality Control; Quinine; Sulfadoxine | 2006 |
Pharmacokinetic determinants of the window of selection for antimalarial drug resistance.
Topics: Algorithms; Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Computer Simulation; Drug Resistance; Malaria; Mefloquine; Models, Theoretical; Pyrimethamine; Quinine | 2008 |
Antimalarial drugs inhibit human 5-HT(3) and GABA(A) but not GABA(C) receptors.
Topics: Animals; Antimalarials; Binding, Competitive; Cells, Cultured; Chloroquine; Electrophysiology; Female; GABA-A Receptor Antagonists; Humans; Inhibitory Concentration 50; Mefloquine; Oocytes; Quinine; Receptors, GABA; Serotonin 5-HT3 Receptor Antagonists; Xenopus laevis | 2008 |
Malaria in Egypt, Saudi Arabia and Yemen: a clinical pilot study.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Egypt; Female; Humans; Infant; Malaria; Male; Mefloquine; Middle Aged; Pilot Projects; Quinine; Saudi Arabia; Severity of Illness Index; Yemen | 2007 |
Malaria--an experience at CMH Khuzdar (Balochistan).
Topics: Antimalarials; Chloroquine; Disease Outbreaks; Doxycycline; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Pakistan; Parasitemia; Quinine; Treatment Outcome | 2008 |
Quinine and chloroquine differentially perturb heme monomer-dimer equilibrium.
Topics: Chloroquine; Dimerization; Heme; Hemin; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Magnetics; Quinine | 2008 |
Diminished Plasmodium falciparum sensitivity to quinine exposure in vitro and in a sequential multi-drug regimen: A preliminary investigation in Guyana, South America.
Topics: Animals; Antimalarials; Child; Chloroquine; Doxycycline; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Guyana; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Treatment Outcome; Young Adult | 2008 |
Chloroquine resistant vivax malaria in an infant: a report from India.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Female; Humans; India; Infant; Malaria, Vivax; Quinine; Treatment Outcome | 2008 |
Stereoselective C9 carbon-carbon couplings of quinine: synthesis and conformational analysis of new C2-symmetric dimers.
Topics: Carbon; Chloroquine; Crystallography, X-Ray; Dimerization; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Organometallic Compounds; Quinine; Stereoisomerism | 2008 |
A field trial of chloroquine (SN 7618) as a suppressive against malaria in the Philippines.
Topics: Chloroquine; Humans; Malaria; Philippines; Quinine | 1948 |
Comparison of chloroquine, quinacrine (atabrine) and quinine in the treatment of acute attacks of sporozoite-induced vivax malaria, Chesson strain.
Topics: Animals; Behavior, Animal; Chloroquine; Humans; Malaria, Vivax; Quinacrine; Quinine; Sporozoites | 1948 |
The efficacy of chloroquine, quinacrine, quinine and totaquine in the treatment of Plasmodium malariae infections (quartan malaria).
Topics: Chloroquine; Humans; Malaria; Plasmodium malariae; Quinacrine; Quinine | 1948 |
Malaria; observations on treatment with chloroquine (SN7618) and combined quinine and plasmochin.
Topics: Chloroquine; Humans; Malaria; Quinine | 1948 |
Chloroquine resistant vivax malaria in an infant: a report from India.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Infant; Malaria, Vivax; Male; Plasmodium vivax; Quinine | 2009 |
In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays.
Topics: Administration, Oral; Adolescent; Animals; Antigens, Protozoan; Antimalarials; Artemisinins; Artesunate; Biological Assay; Child; Child, Preschool; Chloroquine; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Female; Gabon; Humans; Infant; Malaria, Falciparum; Male; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinine; Regression Analysis | 2009 |
Drug resistance and in vitro susceptibility of Plasmodium falciparum in Thailand during 1988-2003.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Thailand | 2009 |
Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Gene Dosage; Genetic Markers; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Myanmar; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Thailand | 2010 |
Quinine for the treatment of malaria in pregnancy.
Topics: Animals; Antimalarials; Azithromycin; Chloroquine; Clindamycin; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Quinine | 2010 |
Decreased in vitro susceptibility of Plasmodium falciparum isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001 to 2007.
Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance, Bacterial; Geographic Information Systems; In Vitro Techniques; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Oligonucleotide Array Sequence Analysis; Plasmodium falciparum; Point Mutation; Polymorphism, Single Nucleotide; Quinine | 2010 |
Association of microsatellite variations of Plasmodium falciparum Na+/H+ exchanger (Pfnhe-1) gene with reduced in vitro susceptibility to quinine: lack of confirmation in clinical isolates from Africa.
Topics: Africa; Amino Acid Sequence; Animals; Antimalarials; Chloroquine; Drug Resistance; Genotype; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Microsatellite Repeats; Molecular Sequence Data; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Sequence Alignment; Sodium-Hydrogen Exchangers | 2010 |
Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue.
Topics: Antimalarials; Binding Sites; Chloroquine; Drug Resistance, Multiple; Mefloquine; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protein Binding; Quinine | 2010 |
Residual antimalarial concentrations before treatment in patients with malaria from Cambodia: indication of drug pressure.
Topics: Adolescent; Adult; Antimalarials; Cambodia; Child; Child, Preschool; Chloroquine; Chromatography, Liquid; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Quinine; Quinolines; Selection, Genetic; Serum; Tandem Mass Spectrometry; Young Adult | 2010 |
In-vitro culture of Plasmodium falciparum: utility of modified (RPNI) medium for drug-sensitivity studies using SYBR Green I assay.
Topics: Antimalarials; Artemether; Artemisinins; Benzothiazoles; Chloroquine; Culture Media; Diamines; Fluorescent Dyes; Mefloquine; Organic Chemicals; Plasmodium falciparum; Quinine; Quinolines | 2011 |
Plasmodium falciparum: Solanum nudum SN-1 steroid antiplasmodial activity when combined with antimalarial drugs.
Topics: Amodiaquine; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Synergism; Erythrocytes; Flow Cytometry; Humans; Phytosterols; Plasmodium falciparum; Quinine; Solanum; Trophozoites | 2011 |
The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dimerization; Dose-Response Relationship, Drug; Hemeproteins; Hemin; Hydroxyl Radical; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Malaria, Falciparum; Nitrogen; Plasmodium falciparum; Quinine | 2011 |
Chloroquine for treatment of acute attacks of vivax malaria.
Topics: Animals; Behavior, Animal; Chloroquine; Humans; Malaria; Malaria, Vivax; Quinine; Social Behavior | 1946 |
ACTIVITY of a new antimalarial agent, chloroquine (SN 7618).
Topics: Anaphylaxis; Antimalarials; Chloroquine; Humans; Hypersensitivity; Immune System Diseases; Malaria; Quinine; Vaccines | 1946 |
[Plasmodium ovale malaria severity].
Topics: Adult; Antimalarials; Chloroquine; Female; Ghana; Humans; Malaria; Male; Nigeria; Plasmodium ovale; Quinine; Respiration, Artificial; Respiratory Distress Syndrome | 2011 |
In vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na+/H+ exchanger (Pfnhe-1) gene: the absence of association in clinical isolates from the Republic of Congo.
Topics: Amino Acid Sequence; Antimalarials; Chloroquine; Congo; Drug Resistance; Genotype; Humans; Inhibitory Concentration 50; Insect Proteins; Malaria, Falciparum; Microsatellite Repeats; Molecular Sequence Data; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Sequence Alignment; Sodium-Hydrogen Exchangers | 2011 |
In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs.
Topics: Amodiaquine; Antimalarials; Chloroquine; Ethanolamines; Fluorenes; Inhibitory Concentration 50; Lumefantrine; Mefloquine; Methylene Blue; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine | 2011 |
Simple flow cytometric detection of haemozoin containing leukocytes and erythrocytes for research on diagnosis, immunology and drug sensitivity testing.
Topics: Animals; CD11b Antigen; Chloroquine; Erythrocyte Count; Erythrocytes; Flow Cytometry; Hemeproteins; Humans; Leukocyte Count; Leukocytes; Lipopolysaccharide Receptors; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Quinine; Receptors, Cell Surface; Receptors, IgG; Sensitivity and Specificity | 2011 |
HPLC with ultraviolet detection for the determination of chloroquine and desethylchloroquine in whole blood and finger-prick capillary blood dried on filter paper.
Topics: Animals; Blood; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chloroquine; Chromatography; Chromatography, High Pressure Liquid; Clinical Chemistry Tests; Humans; Models, Chemical; Plasmodium vivax; Quality Control; Quinine; Reproducibility of Results; Spectrophotometry, Ultraviolet; Ultraviolet Rays | 2011 |
Severe Plasmodium knowlesi malaria in a tertiary care hospital, Sabah, Malaysia.
Topics: Acute Kidney Injury; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Ethanolamines; Female; Fluorenes; Hospitals, Urban; Humans; Lumefantrine; Malaria; Malaysia; Microscopy; Middle Aged; Parasitemia; Patient Selection; Plasmodium knowlesi; Polymerase Chain Reaction; Quinine; Respiratory Distress Syndrome; Severity of Illness Index; Shock; Survival Rate | 2011 |
Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta).
Topics: Aminoquinolines; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Chromatography, Liquid; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Macaca mulatta; Malaria; Male; Mass Spectrometry; Mefloquine; Plasma; Plasmodium cynomolgi; Primate Diseases; Quinine; Treatment Outcome | 2011 |
Quality of essential drugs in tropical countries: evaluation of antimalarial drugs in the Brazilian Health System.
Topics: Antimalarials; Brazil; Chloroquine; Chromatography, High Pressure Liquid; Drug Storage; Drugs, Essential; Humans; Mefloquine; Primaquine; Quality Control; Quinine | 2011 |
Extracellular heme enhances the antimalarial activity of artemisinin.
Topics: Antimalarials; Antioxidants; Artemisia; Artemisinins; Chloroquine; Cholesterol, LDL; Fluorescence; Heme; Hemin; Humans; Lipid Peroxidation; Mefloquine; Oxidants; Oxidation-Reduction; Plasmodium falciparum; Quinine; Tryptophan; Vitamin E | 2012 |
Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana.
Topics: Aminoquinolines; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Evolution, Molecular; Fluorenes; French Guiana; Gene Dosage; Haplotypes; Humans; Inhibitory Concentration 50; Longitudinal Studies; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Practice Guidelines as Topic; Protozoan Proteins; Quinine | 2012 |
Mosquito infection studies with Aotus monkeys and humans infected with the Chesson strain of Plasmodiun vivax.
Topics: Animals; Anopheles; Antimalarials; Aotidae; Chloroquine; Disease Management; Disease Models, Animal; Host-Parasite Interactions; Humans; Malaria; Male; Monkey Diseases; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinine | 2012 |
The in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine.
Topics: Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Malaria; Male; Methylene Blue; Mice; Plasmodium berghei; Pyrimethamine; Quinine | 2012 |
In vitro susceptibility of Plasmodium falciparum Welch field isolates to infusions prepared from Artemisia annua L. cultivated in the Brazilian Amazon.
Topics: Antimalarials; Artemisia annua; Artemisinins; Brazil; Chloroquine; Drug Synergism; Inhibitory Concentration 50; Parasitic Sensitivity Tests; Plant Extracts; Plasmodium falciparum; Quinine | 2012 |
Defining the timing of action of antimalarial drugs against Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Flow Cytometry; High-Throughput Screening Assays; Hydroxamic Acids; Inhibitory Concentration 50; Mefloquine; Merozoites; Plasmodium falciparum; Quinine; Quinolines; Schizonts; Time Factors | 2013 |
Ketoconazole, a cytochrome P(450) inhibitor can potentiate the antimalarial action of α/β arteether against MDR Plasmodium yoelii nigeriensis.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Multiple; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ketoconazole; Liver; Malaria; Male; Mefloquine; Mice; Plasmodium falciparum; Plasmodium yoelii; Quinine | 2013 |
Comparative study of chloroquine and quinine on malaria rodents and their effects on the mouse testis.
Topics: Animals; Antimalarials; Chloroquine; Disease Models, Animal; Malaria; Male; Mice; Orchitis; Parasitemia; Plasmodium berghei; Quinine; Testis | 2012 |
Synthesis and evaluation of 7-chloro-4-(piperazin-1-yl)quinoline-sulfonamide as hybrid antiprotozoal agents.
Topics: Amino Acid Sequence; Antiprotozoal Agents; Cell Survival; Chloroquine; Crystallography, X-Ray; Dihydropteroate Synthase; Drug Resistance; Entamoeba histolytica; Erythrocytes; Hemeproteins; Hemolysis; Humans; Molecular Docking Simulation; Molecular Sequence Data; Piperazines; Plasmodium falciparum; Protozoan Proteins; Quinine; Quinolines; Structure-Activity Relationship | 2013 |
High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.
Topics: Amodiaquine; Antimalarials; Artemisinins; Automation, Laboratory; Chloroquine; Drug Resistance; Drug Therapy, Combination; High-Throughput Screening Assays; Internet; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine | 2013 |
Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.
Topics: Amino Acid Motifs; Antimalarials; Artemisinins; Asparagine; Aspartic Acid; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Genome, Protozoan; Lumefantrine; Mefloquine; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine | 2013 |
Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity.
Topics: Airway Resistance; Animals; Bronchodilator Agents; Caffeine; Calcium Channel Blockers; Calcium Signaling; Chloroquine; Drug Resistance; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lung; Mice; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Ryanodine; Taste | 2014 |
Four years' monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Seasons; Thailand; Time Factors | 2014 |
Cytometric measurement of in vitro inhibition of Plasmodium falciparum field isolates by drugs: a new approach for re-invasion inhibition study.
Topics: Antimalarials; Benzothiazoles; Chloroquine; Drug Resistance; Flow Cytometry; Fluorescent Dyes; Inhibitory Concentration 50; Phenanthridines; Plasmodium falciparum; Quinine; Quinolines | 2014 |
Quality of antimalarial drugs and antibiotics in Papua New Guinea: a survey of the health facility supply chain.
Topics: Amodiaquine; Amoxicillin; Antimalarials; Artemether; Artemisinins; Biosimilar Pharmaceuticals; Chloroquine; Drug Resistance; Health Facilities; Humans; Malaria, Falciparum; Malaria, Vivax; Papua New Guinea; Primaquine; Quality Control; Quinine | 2014 |
Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle.
Topics: Aged; Animals; Aorta, Thoracic; Chloroquine; Colon; Dextromethorphan; Female; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Mice, Knockout; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Noscapine; Pulmonary Artery; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Saccharin; Taste; Trachea | 2014 |
In vitro susceptibility of Plasmodium vivax to antimalarials in Colombia.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Colombia; Drug Resistance; Malaria, Vivax; Mefloquine; Parasitic Sensitivity Tests; Plasmodium vivax; Quinine | 2014 |
Role of Pfmdr1 in in vitro Plasmodium falciparum susceptibility to chloroquine, quinine, monodesethylamodiaquine, mefloquine, lumefantrine, and dihydroartemisinin.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Biological Transport; Child; Chloroquine; Drug Resistance; Erythrocytes; Ethanolamines; Female; Fluorenes; Gene Expression; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinine; Senegal | 2014 |
Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites.
Topics: Animals; Antimalarials; Binding Sites; Binding, Competitive; Biological Transport; Cells, Cultured; Chloroquine; Drug Resistance; Female; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Quinidine; Quinine; Verapamil; Xenopus laevis | 2014 |
Evaluation of malaria cases in individuals after traveling to endemic regions of the world.
Topics: Adult; Chloroquine; Doxycycline; Female; Humans; Malaria; Male; Quinine; Travel | 2014 |
Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children.
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Clinical Trials as Topic; Ethanolamines; Fluorenes; Humans; Infant; Lumefantrine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Quinolines; Uganda | 2015 |
Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Lumefantrine; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Quinine; Quinolines; Senegal; Ubiquitin-Protein Ligases | 2016 |
Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter.
Topics: Amantadine; Animals; Antimalarials; Biological Transport; Blotting, Western; Chloroquine; Drug Resistance; Fluorescent Antibody Technique; Humans; Malaria, Falciparum; Membrane Transport Proteins; Mutagenesis, Site-Directed; Plasmodium falciparum; Protein Isoforms; Protozoan Proteins; Quinine; Xenopus laevis | 2016 |
The expression of bitter taste receptors in mesenteric, cerebral and omental arteries.
Topics: Animals; Cerebral Arteries; Cerebrovascular Circulation; Chloroquine; Female; Gene Expression Regulation; Humans; Liver; Male; Mesentery; Microscopy, Fluorescence; Middle Aged; Omentum; Quinine; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taste; Tongue; Vasodilation | 2017 |
In vitro sensitivity of antimalarial drugs and correlation with clinico-parasitological response following treatment with a 3-day artesunate-mefloquine combination in patients with falciparum malaria along the Thai-Myanmar border.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Myanmar; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Thailand; Young Adult | 2017 |
Association between Polymorphisms in the Pf
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal | 2017 |
Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Chemotaxis; Chloroquine; Cytokines; Disease Models, Animal; Female; Humans; Hypersensitivity; Immunization; Inflammation; Lung; Matrix Metalloproteinases; Mice, Inbred BALB C; Mucus; Muscle, Smooth; Neutrophils; Pyroglyphidae; Quinine; Receptors, G-Protein-Coupled; Taste | 2017 |
Heterologous Expression of a Novel Drug Transporter from the Malaria Parasite Alters Resistance to Quinoline Antimalarials.
Topics: Amino Acid Transport Systems; Amodiaquine; Animals; Antimalarials; Biological Transport; Chloroquine; Conserved Sequence; Drug Resistance; Gene Expression; Humans; Mefloquine; Mutation; Plasmodium chabaudi; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinine; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transgenes | 2018 |
Topics: Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Atovaquone; Azithromycin; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Humans; India; Lumefantrine; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 2017 |
Nanomolar binding affinity of quinine-based antimalarial compounds by the cocaine-binding aptamer.
Topics: Amodiaquine; Antimalarials; Aptamers, Nucleotide; Binding Sites; Chloroquine; Cocaine; Ligands; Mefloquine; Primaquine; Quinine; Thermodynamics | 2018 |
Monocyte phagocytosis of malaria β-haematin in the presence of artemisinin, amodiaquine, chloroquine, doxycycline, primaquine, pyrimethamine and quinine.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Cell Count; Cell Line; Chloroquine; Doxycycline; Electron Probe Microanalysis; Heme; Hemeproteins; Humans; Leukocytes, Mononuclear; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Monocytes; Peroxidase; Phagocytosis; Primaquine; Pyrimethamine; Quinine; Spectrophotometry; Temperature; U937 Cells | 2019 |
Adherence to antimalarial drug policy among doctors in Delta State, Nigeria: implications for malaria control.
Topics: Adult; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Chloroquine; Drug Resistance, Microbial; Female; Guideline Adherence; Health Policy; Humans; Malaria, Falciparum; Male; Middle Aged; Nigeria; Plasmodium falciparum; Practice Guidelines as Topic; Practice Patterns, Physicians'; Quinine; Surveys and Questionnaires; Young Adult | 2019 |
The bitter taste receptor agonist-induced negative chronotropic effects on the Langendorff-perfused isolated rat hearts.
Topics: Animals; Chloroquine; Gene Expression; Heart Rate; Heart Ventricles; In Vitro Techniques; Isolated Heart Preparation; Male; Protein Subunits; Quinine; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Sinoatrial Node | 2020 |
Ex-vivo Sensitivity of Plasmodium falciparum to Common Anti-malarial Drugs: The Case of Kéniéroba, a Malaria Endemic Village in Mali.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Endemic Diseases; Humans; Infant; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mali; Mefloquine; Plasmodium falciparum; Quinine; Quinolines | 2020 |
Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in Northern Uganda.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Lumefantrine; Mefloquine; Plasmodium falciparum; Quinine; Uganda | 2021 |
Atovaquone, chloroquine, primaquine, quinine and tetracycline: antiproliferative effects of relevant antimalarials on Neospora caninum.
Topics: Antimalarials; Atovaquone; Chloroquine; Neospora; Primaquine; Quinine; Tetracyclines | 2021 |
Quinine Inhibits Infection of Human Cell Lines with SARS-CoV-2.
Topics: A549 Cells; Animals; Caco-2 Cells; Cell Line; Cell Survival; Chlorocebus aethiops; Chloroquine; Colon; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Lung; Middle Aged; Quinine; SARS-CoV-2; Vero Cells | 2021 |
Historical 8-Aminoquinoline Combinations: Not All Antimalarial Drugs Work Well Together.
Topics: Aminoquinolines; Antimalarials; Chloroquine; Hemolysis; Humans; Primaquine; Quinine | 2022 |
[Malaria in 2022: clinical and therapeutic aspects].
Topics: Antimalarials; Chloroquine; Humans; Malaria, Cerebral; Plasmodium; Quinine | 2023 |