chloroquine and quinidine

chloroquine has been researched along with quinidine in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (35.80)	18.7374
1990's	10 (12.35)	18.2507
2000's	24 (29.63)	29.6817
2010's	18 (22.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Choi, WS; Choi, YJ; Huh, SC; Huh, TL; Kim, DY; Kim, JE; Kim, MH; Kim, SM; Lee, BJ; Lee, SE; Park, BS; Park, E-; Rosenthal, PJ; Suh, KH	1
Galanakis, D; Ganellin, CR	1
Caron, G; Ermondi, G; Lorenti, M	1
Harada, S; Huy, NT; Kamei, K; Maeda, A; Oida, T; Trang, DT; Uyen, DT	1
Acharya, BN; Kaushik, MP; Saraswat, D	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y	1
Dinio, T; Gorka, AP; McGinniss, A; Morgan, JB; Roepe, PD	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Caridha, D; Gerena, L; Korotchenko, V; Kreishman-Deitrick, M; Li, Q; Lin, AJ; Sathunuru, R; Smith, PL	1
Albuquerque, IS; Burojević, J; D'Alessandro, S; Djurković-Djaković, O; Konstantinović, J; Machado, M; Pecic, S; Prudêncio, M; Sciotti, RJ; Šolaja, BA; Srbljanović, J; Štajner, T; Taramelli, D; Terzić, N; Tot, M; Verbić, T; Zlatović, M	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Combrinck, JM; Egan, TJ; Hunter, R; Smith, PJ; Wicht, KJ	1
Battista, MR; Brun, R; Calvet, CM; Cirilli, R; Costi, R; De Leo, A; De Vita, D; Di Marco, A; Di Santo, R; Faggi, C; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pepe, G; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Summa, V; Tudino, V	1
Horrobin, DF; Manku, MS	2
Scott, WA; Solomon, B	1
Garber, G; Thind, J	1
Bazill, GW; Dexter, TM	1
Bunnag, D; Chittamas, S; Harinasuta, T; Looareesuwan, S; White, NJ	1
Brubaker, G; Draper, CC; Hills, M; Kilimali, VA	1
Chan, LA; Matsuura, GK	1
Chanthavanich, P; Karbwang, J; Looareesuwan, S; Phillips, RE; Supanaranond, W; Turner, RC; Warrell, DA; White, NJ	1
Bunnag, D; Chittamas, S; Harinasuta, T; Jochims, E; Looareesuwan, S; Punnavut, W; Vanijanonta, S	1
Buregea, H; Cibanguka, J; Delacollette, C; Nkera, J	1
Holmes, J; Sapeika, N; Zwarenstein, H	2
Alekseev, GK	1
Fain, JN; Pointer, RH	1
Alvarez Sotolongo, M; Krácmar, J; Krácmarová, J	1
Ball, EG; Markus, HB	1
Balwani, JH; Kulkarni, SD; Phansalkar, AG	1
Krishan, I; Malhotra, V	1
Lamela, M	1
Balasubramanian, D; Mohan Rao, C; Panijpan, B	1
Chiodini, PL; Ellis, CJ	1
Turner, GD	1
Bennett, T; Lot, TY	1
Schubarth, P	1
Krishna, S; White, NJ	1
Gawdi, G; Misra, UK; Pizzo, SV	1
Akkawi, M; Blauer, G	1
Gros, P; Housman, D; Kast, C; Landers, J; Pelletier, J; Prawitt, D; Reece, M; Zabel, BU	1
Goldberg, DE; Matile, H; Ridley, RG; Sullivan, DJ	1
Burgel, PR; Camara, P; Hovette, P; Klotz, F; Mbaye, PS; Sane, M	1
Brasch, F; Falk, S; Göggel, R; Heydasch, U; Müller, KM; Uhlig, S; Wendel, A	1
Dasgupta, A; Paul, A; Wells, A	1
Bachhawat, K; Surolia, A; Surolia, N; Thomas, CJ	1
Cooper, RA; Ferdig, MT; Fidock, DA; Fujioka, H; Mu, J; Nomura, T; Roepe, PD; Su, XZ; Ursos, LM; Wellems, TE	1
De Dios, AC; DuBay, K; Leed, A; Roepe, PD; Sears, D; Ursos, LM	1
McCracken, MA; Strobl, JS; Zhou, Q	1
KURNICK, NB; RADCLIFFE, IE	1
ARORA, RB; LAL, A	1
ARIAS, IM; FURMAN, M; GARTNER, L; WOLFSON, S	1
ABELS, J; BOUMA, HG; NIEWEG, HO; SOEPARMAN, R	1
BONAMOUR, G; DIDIER-LAURENT, A	1
BESSON, H	1
CARBONELL, LM; SANABRIA, A; SOTO, R	1
Beg, MA; Khan, MA; Razi, ST; Smego, RA	1
Emerson, LR; Kuchler, K; Skillman, BC; Wirth, DF; Wolfger, H	1
Casabianca, LB; de Dios, AC; Kosar, A; Roepe, PD	1
Brzostowski, JA; Kimmel, AR; Naudé, B; Wellems, TE	1
Ballestero, JA; Elgoyhen, AB; Gómez-Casati, ME; Katz, E; Kracun, S; Millar, NS; Plazas, PV; Rothlin, CV; Taranda, J	1
Cooper, RA; Deng, B; Ferdig, MT; Lane, KD; Mu, J; Patel, JJ; Su, X; Wellems, TE	1
Ferrer-Villada, T; Jalife, J; López-Izquierdo, A; Noujaim, SF; Pandit, SV; Ponce-Balbuena, D; Sánchez-Chapula, JA; Stuckey, JA	1
Bellanca, S; Dave, A; Dittmer, M; Lanzer, M; Martin, RE; Meyrath, M; Nash, MN; Sanchez, CP; Stein, WD; Summers, RL	1
Abraham, GM; Al Hammadi, A; Mitchell, M; Wang, JP	1

Reviews

4 review(s) available for chloroquine and quinidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Malaria: the most important emergency in subjects returning from the tropics]. Schweizerische medizinische Wochenschrift, 1993, May-01, Volume: 123, Issue:17 Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Emergencies; Humans; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium; Pyrimethamine; Quinidine; Quinine; Sulfadoxine	1993
Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications. Clinical pharmacokinetics, 1996, Volume: 30, Issue:4 Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Interactions; Drug Therapy, Combination; Malaria, Falciparum; Molecular Conformation; Quinidine; Quinine	1996
Emerging drug--resistance and guidelines for treatment of malaria. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2004, Volume: 14, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Pakistan; Phenanthrenes; Plasmodium falciparum; Quinidine; Quinine; Sesquiterpenes; Time Factors	2004

Trials

1 trial(s) available for chloroquine and quinidine

Article	Year
Slow-release quinidine in the treatment of chloroquine resistant falciparum malaria: a double-blind trial. Acta Leidensia, 1987, Volume: 55 Topics: Adolescent; Adult; Animals; Chloroquine; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Drug Resistance; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinidine; Random Allocation	1987

Other Studies

76 other study(ies) available for chloroquine and quinidine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Synthesis and evaluation of new antimalarial analogues of quinoline alkaloids derived from Cinchona ledgeriana Moens ex Trimen. Bioorganic & medicinal chemistry letters, 2002, May-20, Volume: 12, Issue:10 Topics: Animals; Antimalarials; Chloroquine; Cinchona Alkaloids; Drug Design; Drug Resistance; Erythrocytes; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Plasmodium; Quinolines; Structure-Activity Relationship	2002
Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry. Bioorganic & medicinal chemistry letters, 2004, Aug-02, Volume: 14, Issue:15 Topics: Animals; Apamin; Guinea Pigs; Hepatocytes; Kinetics; Molecular Conformation; Potassium Channels, Calcium-Activated	2004
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction. Journal of medicinal chemistry, 2004, Jul-29, Volume: 47, Issue:16 Topics: Chromatography, Affinity; Hydrogen-Ion Concentration; Ions; Models, Molecular; Molecular Conformation; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin, Bovine; Ultracentrifugation	2004
Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1 Topics: Animals; Antimalarials; Colorimetry; Crystallization; Drug Evaluation, Preclinical; Heme; Hemeproteins; Plasmodium falciparum; Polysorbates; Reproducibility of Results	2007
Pharmacophore based discovery of potential antimalarial agent targeting haem detoxification pathway. European journal of medicinal chemistry, 2008, Volume: 43, Issue:12 Topics: Animals; Antimalarials; Drug Discovery; Heme; Isoniazid; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Small Molecule Libraries; Stereoisomerism	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26 Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061 Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites	2011
Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum. Bioorganic & medicinal chemistry, 2012, May-15, Volume: 20, Issue:10 Topics: Antimalarials; Chloroquine; Cinchona Alkaloids; Drug Resistance; Inhibitory Concentration 50; Molecular Structure; Plasmodium falciparum; Quinine	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Antimalarial activity of 4-amidinoquinoline and 10-amidinobenzonaphthyridine derivatives. Journal of medicinal chemistry, 2015, Apr-23, Volume: 58, Issue:8 Topics: Animals; Antimalarials; Hep G2 Cells; Humans; Malaria; Malaria, Falciparum; Male; Mice; Naphthyridines; Plasmodium berghei; Plasmodium falciparum; Quinolines	2015
Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials? Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1 Topics: Aminoquinolines; Animals; Antimalarials; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; Hemin; Hepatocytes; Humans; In Vitro Techniques; Liver; Mice; Microsomes, Liver; Parasite Load; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Tetraoxanes	2016
Identification and SAR Evaluation of Hemozoin-Inhibiting Benzamides Active against Plasmodium falciparum. Journal of medicinal chemistry, 2016, 07-14, Volume: 59, Issue:13 Topics: Antimalarials; Benzamides; Dose-Response Relationship, Drug; Hemeproteins; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2016
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents. Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Animals; Antiprotozoal Agents; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Drug Evaluation, Preclinical; Humans; Imidazoles; Parasitic Sensitivity Tests; Trypanosoma	2019
Chloroquine, quinine, procaine, quinidine, tricyclic antidepressants, and methylxanthines as prostaglandin agonists and antagonists. Lancet (London, England), 1976, Nov-20, Volume: 2, Issue:7995 Topics: Antidepressive Agents, Tricyclic; Antimalarials; Chloroquine; Ductus Arteriosus, Patent; Humans; Infant; Procaine; Prostaglandin Antagonists; Quinidine; Quinine; Xanthines	1976
Adenosine 3',5'-cyclic monophosphate and morphology in Neurospora crassa: drug-induced alterations. Journal of bacteriology, 1975, Volume: 122, Issue:2 Topics: Adenylyl Cyclases; Antimalarials; Atropine; Chloroquine; Cyclic AMP; Histamine; Kinetics; Neurospora; Neurospora crassa; Phosphoric Diester Hydrolases; Quinidine; Quinine; Theophylline	1975
Chloroquine, quinine, procaine, quinidine and clomipramine are prostaglandin agonists and antagonists. Prostaglandins, 1976, Volume: 12, Issue:5 Topics: Animals; Blood Flow Velocity; Blood Pressure; Chloroquine; Clomipramine; Dibenzazepines; Indomethacin; Male; Mesenteric Arteries; Norepinephrine; Procaine; Prostaglandin Antagonists; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Quinidine; Quinine; Rats	1976
Death from a severe case of Plasmodium falciparum in a Canadian. Canada communicable disease report = Releve des maladies transmissibles au Canada, 1992, May-15, Volume: 18, Issue:9 Topics: Adult; Animals; Antimalarials; Cause of Death; Chloroquine; Drug Combinations; Female; Humans; Malaria, Falciparum; Multiple Organ Failure; Plasmodium falciparum; Pyrimethamine; Quinidine; Sulfadoxine; Travel	1992
Role of endocytosis in the action of ether lipids on WEHI-3B, HL60, and FDCP-mix A4 cells. Cancer research, 1990, Dec-01, Volume: 50, Issue:23 Topics: Animals; Antineoplastic Agents; Azepines; Cell Survival; Chloroquine; Diltiazem; Drug Synergism; Endocytosis; Furans; Humans; Hydroxyzine; In Vitro Techniques; Leukemia, Myeloid; Mice; Nifedipine; Phospholipid Ethers; Platelet Activating Factor; Pyridines; Quinidine; Quinine; Sodium Fluoride; Thiazoles; Triazoles; Verapamil	1990
High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand. Lancet (London, England), 1987, Nov-07, Volume: 2, Issue:8567 Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Chloroquine; Female; Follow-Up Studies; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Quinidine; Quinine; Quinolines; Recurrence; Thailand	1987
Serial studies on the evolution of drug resistance in malaria in an area of east Africa: findings from 1979 up to 1986. The Journal of tropical medicine and hygiene, 1988, Volume: 91, Issue:5 Topics: Age Factors; Amodiaquine; Animals; Antibodies, Protozoan; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Quinolines; Sulfadoxine; Tanzania	1988
Ineffectiveness of continuous quinidine gluconate infusion in the treatment of severe chloroquine-resistant Plasmodium falciparum malaria. Drug intelligence & clinical pharmacy, 1988, Volume: 22, Issue:11 Topics: Animals; Chloroquine; Drug Resistance; Humans; Infusions, Intravenous; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinidine	1988
Hypoglycaemia and antimalarial drugs: quinidine and release of insulin. British medical journal (Clinical research ed.), 1986, May-17, Volume: 292, Issue:6531 Topics: Amodiaquine; Antimalarials; Blood Glucose; Chloroquine; Humans; Hypoglycemia; Insulin; Mefloquine; Phenanthrenes; Quinidine; Quinolines; Thailand	1986
Compared response to chloroquine, fansidar, quinine, and quinidine slow release of infections with Plasmodium falciparum in the Kivu region of Zaire. Acta Leidensia, 1987, Volume: 55 Topics: Animals; Antimalarials; Chloroquine; Delayed-Action Preparations; Democratic Republic of the Congo; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Sulfadoxine; Sulfanilamides	1987
Effect of quinoline, phthalazine and coumarin derivatives on the absorbance of NADPH. Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1 Topics: Chloroquine; Coumarins; Heterocyclic Compounds; Hydralazine; Indophenol; NADP; Novobiocin; Quinacrine; Quinidine; Quinine; Quinolines; Spectrophotometry; Warfarin	1974
[Observations on the treatment of certain forms of arrhythmia using contemporary methods]. Kardiologiia, 1968, Volume: 8, Issue:1 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Cardiac Glycosides; Chloroquine; Electric Countershock; Female; Humans; Male; Middle Aged; Procainamide; Quinidine; Sympathomimetics; Tachycardia; Thiamine Pyrophosphate	1968
Response of isolated white fat cells to anti-malarial drugs. Biochemical pharmacology, 1973, Dec-01, Volume: 22, Issue:23 Topics: Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Antimalarials; Bucladesine; Chloroquine; Drug Synergism; Fatty Acids, Nonesterified; Female; Glycerol; Norepinephrine; Primaquine; Proteins; Quinacrine; Quinidine; Rats; Theophylline; Triglycerides	1973
[UV-spectrophotometry in drug control. 14. Characterization and determination of drugs with quinoline and isoquinoline chromophores]. Die Pharmazie, 1974, Volume: 29, Issue:12 Topics: Amodiaquine; Chloroquine; Hydroxychloroquine; Isoquinolines; Papaverine; Primaquine; Quinidine; Quinine; Quinolines; Spectrophotometry, Ultraviolet	1974
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro. Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2 Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts	1973
Inhibition of lipolytic processes in rat adipose tissue by antimalaria drugs. Biochimica et biophysica acta, 1969, Dec-17, Volume: 187, Issue:4 Topics: Adipose Tissue; Animals; Antimalarials; Chloroquine; Epididymis; Fatty Acids; Heparin; Hydroxychloroquine; Lipid Metabolism; Male; Primaquine; Quinacrine; Quinidine; Quinine; Rats	1969
Influence of some antiarrhythmic agents on electrically induced convulsive seizures in rats. Indian journal of physiology and pharmacology, 1970, Jul-03, Volume: 14, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Chloroquine; Electroshock; Female; Lidocaine; Male; Phenytoin; Procainamide; Procaine; Quinidine; Quinine; Rats; Seizures; Time Factors; Water	1970
Resistant ventricular tachycardia responsive to chloroquine. Indian heart journal, 1968, Volume: 20, Issue:2 Topics: Chloroquine; Humans; Male; Middle Aged; Myocardial Infarction; Procainamide; Quinidine; Tachycardia, Paroxysmal	1968
Combined effects of antiarrhythmic drugs on the experimentally induced fibrillation of isolated rat's atria. Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 157, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atropine; Chloroquine; Diphenhydramine; Heart Atria; Heart Rate; In Vitro Techniques; Phenformin; Quinidine; Rats; Sparteine	1965
Interaction of antimalarial drugs with hemin. Bioscience reports, 1983, Volume: 3, Issue:12 Topics: Animals; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Circular Dichroism; Heme; Hemin; Plasmodium berghei; Quinidine; Quinine; Spectrometry, Fluorescence; Spectrum Analysis	1983
The treatment of falciparum malaria. The Journal of antimicrobial chemotherapy, 1984, Volume: 13, Issue:4 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinidine; Quinine; Quinolines; Sesquiterpenes	1984
Kenyan chloroquin, fansidar and quninine resistant P. Falciparum. The Central African journal of medicine, 1984, Volume: 30, Issue:7 Topics: Adolescent; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinidine; Sulfadoxine; Sulfanilamides	1984
Comparison of the effects of chloroquine quinacrine and quinidine on autonomic neuroeffector mechanisms. Medical biology, 1982, Volume: 60, Issue:6 Topics: Animals; Autonomic Nervous System; Chickens; Chloroquine; Electric Stimulation; Female; Indomethacin; Male; Mice; Norepinephrine; Quinacrine; Quinidine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Tetrodotoxin	1982
Chloroquine, quinine and quinidine inhibit calcium release from macrophage intracellular stores by blocking inositol 1,4,5-trisphosphate binding to its receptor. Journal of cellular biochemistry, 1997, Volume: 64, Issue:2 Topics: Animals; Antimalarials; Calcium; Calcium Channels; Cell Compartmentation; Chloroquine; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Macrophages, Peritoneal; Mice; Protein Binding; Quinidine; Quinine; Receptors, Cytoplasmic and Nuclear	1997
Investigations of B- and beta-hematin. Journal of inorganic biochemistry, 1997, May-01, Volume: 66, Issue:2 Topics: Amodiaquine; Chloroquine; Hemin; Hydrogen Bonding; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Models, Structural; Quinidine; Solubility; Spectroscopy, Fourier Transform Infrared	1997
Functional characterization of ORCTL2--an organic cation transporter expressed in the renal proximal tubules. FEBS letters, 1998, Aug-21, Volume: 433, Issue:3 Topics: Animals; Bacteria; Base Sequence; Beckwith-Wiedemann Syndrome; Biological Transport; Carrier Proteins; Chloroquine; Chromosome Mapping; Chromosomes, Human, Pair 11; COS Cells; Drug Resistance, Multiple; Humans; Kidney Tubules, Proximal; Kinetics; Membrane Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Organic Cation Transport Proteins; Quinidine; Recombinant Proteins; Tetracycline; Tetracycline Resistance; Transcription, Genetic; Transfection	1998
A common mechanism for blockade of heme polymerization by antimalarial quinolines. The Journal of biological chemistry, 1998, Nov-20, Volume: 273, Issue:47 Topics: Animals; Antimalarials; Chloroquine; Erythrocytes; Heme; Hemeproteins; Mefloquine; Plasmodium falciparum; Polymers; Quinidine; Quinolines	1998
[Pulmonary manifestations associated with malaria]. Revue de pneumologie clinique, 1998, Volume: 54, Issue:6 Topics: Adult; Anti-Bacterial Agents; Antimalarials; Bronchitis; Child; Chloroquine; Female; Humans; Infant, Newborn; Lung Diseases; Malaria, Falciparum; Male; Mefloquine; Oxygen Inhalation Therapy; Phenanthrenes; Pleurisy; Pregnancy; Pregnancy Complications, Parasitic; Pulmonary Edema; Quinidine; Quinine; Respiratory Distress Syndrome, Newborn; Travel	1998
Quinolines attenuate PAF-induced pulmonary pressor responses and edema formation. American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:5 Pt 1 Topics: Airway Resistance; Animals; Aspirin; Benzoquinones; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Chloroquine; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; In Vitro Techniques; Interleukin-6; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Pulmonary Circulation; Pulmonary Edema; Quinidine; Quinine; Quinolines; Rats; Rats, Wistar; Receptors, Thromboxane; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction	1999
Stereospecificity of antibody: quinine, the optical isomer of quinidine and anti-malarial drug chloroquine do not cross-react with quinidine immunoassays. Therapeutic drug monitoring, 2000, Volume: 22, Issue:2 Topics: Antibodies; Antimalarials; Chloroquine; Cross Reactions; Humans; Immunoassay; Quinidine; Quinine; Stereoisomerism	2000
Interaction of chloroquine and its analogues with heme: An isothermal titration calorimetric study. Biochemical and biophysical research communications, 2000, Oct-05, Volume: 276, Issue:3 Topics: Amodiaquine; Antimalarials; Binding Sites; Calorimetry; Chloroquine; Hemin; Hydrogen-Ion Concentration; Mefloquine; Octoxynol; Quinidine; Quinine; Solubility; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Titrimetry	2000
Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum. Molecular pharmacology, 2002, Volume: 61, Issue:1 Topics: Acridine Orange; Animals; Antimalarials; Calcium Channel Blockers; Chloroquine; Drug Interactions; Drug Resistance; Fluorescence; Membrane Proteins; Membrane Transport Proteins; Molecular Conformation; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinidine; Quinine; Verapamil	2002
Solution structures of antimalarial drug-heme complexes. Biochemistry, 2002, Aug-13, Volume: 41, Issue:32 Topics: Aminoquinolines; Antimalarials; Binding Sites; Chloroquine; Dimerization; Hemin; Hydrogen-Ion Concentration; Macromolecular Substances; Nuclear Magnetic Resonance, Biomolecular; Protons; Quinidine; Quinine; Solutions; Thermodynamics	2002
Control of mammary tumor cell growth in vitro by novel cell differentiation and apoptosis agents. Breast cancer research and treatment, 2002, Volume: 75, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Differentiation; Cell Division; Chloroquine; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Humans; In Vitro Techniques; Intercalating Agents; Ki-67 Antigen; Molecular Structure; Quinidine; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2002
Reaction between DNA and quinacrine and other antimalarials. The Journal of laboratory and clinical medicine, 1962, Volume: 60 Topics: Antimalarials; Chloroquine; DNA; Quinacrine; Quinidine; Quinine	1962
ANTIMALARIAL DRUGS ON THE AUTOMATICITY OF SINO-AURICULAR AND ATRIO-VENTRICULAR NODES. The Indian journal of medical research, 1963, Volume: 51 Topics: Administration, Intravenous; Amodiaquine; Animals; Anti-Arrhythmia Agents; Antimalarials; Atrioventricular Node; Atropine; Chloroquine; Dogs; Heart Conduction System; Humans; Hydroxychloroquine; Hypotension; Injections, Intravenous; Primaquine; Quinacrine; Quinidine; Research; Statistics as Topic	1963
STUDIES OF THE EFFECT OF SEVERAL DRUGS ON HEPATIC GLUCURONIDE FORMATION IN NEWBORN RATS AND HUMANS. Annals of the New York Academy of Sciences, 1963, Dec-30, Volume: 111 Topics: Animals, Newborn; Benzopyrenes; Chloroquine; Glucuronates; Hyperbilirubinemia; Infant, Newborn; Liver; Metabolism; Pregnancy; Pregnancy, Animal; Quinidine; Quinolines; Rats; Research	1963
[CLINICAL STUDY ON CHANGES IN THE BLOOD CAUSED BY DRUGS]. Nederlands tijdschrift voor geneeskunde, 1963, Nov-09, Volume: 107 Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Blood Platelet Disorders; Chloramphenicol; Chloroquine; Drug Hypersensitivity; Drug Therapy; Iatrogenic Disease; Phenylbutazone; Poisoning; Purpura; Purpura, Thrombocytopenic; Quinidine; Thrombocytopenia; Toxicology	1963
[OPHTHALMOLOGICAL COMPLICATIONS OF CERTAIN GENERAL THERAPEUTICS]. Journal de medecine de Lyon, 1964, Mar-05, Volume: 45 Topics: Acetazolamide; Adrenal Cortex Hormones; Anthelmintics; Arsenicals; Barbiturates; Chloroquine; Chlorpromazine; Dinitrophenols; Ophthalmology; Parasympathomimetics; Quinidine; Quinine; Streptomycin; Sulfonamides; Toxicology; Tranquilizing Agents; Vitamin D; Vitamins	1964
[THE HEART AND POISONINGS]. Maroc medical, 1964, Volume: 43 Topics: Chloroquine; Diagnosis; Digitalis Glycosides; Heart; Heart Failure; Imipramine; Prognosis; Quinidine; Quinine; Toxicology	1964
Action of procainamide, quinidine and chloroquine upon the conduction system of the dog's heart (histochemical study). The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1959, Volume: 7 Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Chloroquine; Dogs; Heart; Heart Conduction System; Procainamide; Quinidine	1959
The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs. Annals of tropical medicine and parasitology, 2004, Volume: 98, Issue:6 Topics: Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Cycloheximide; Drug Resistance, Multiple, Fungal; Gene Deletion; Genes, Fungal; Mefloquine; Mutation; Quinacrine; Quinidine; Quinine; Saccharomyces cerevisiae; Transcription, Genetic	2004
Structure of the amodiaquine-FPIX mu oxo dimer solution complex at atomic resolution. Inorganic chemistry, 2004, Dec-13, Volume: 43, Issue:25 Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Quinidine; Quinine	2004
Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT. The Journal of biological chemistry, 2005, Jul-08, Volume: 280, Issue:27 Topics: Acids; Amino Acid Sequence; Animals; Antimalarials; Chloroquine; Cytoplasmic Vesicles; Dictyostelium; Drug Resistance, Bacterial; Gene Expression; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Phenotype; Phylogeny; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinidine; Quinine; Quinolines; Transfection	2005
Effects of quinine, quinidine, and chloroquine on alpha9alpha10 nicotinic cholinergic receptors. Molecular pharmacology, 2005, Volume: 68, Issue:3 Topics: Animals; Antimalarials; Chloroquine; Hair Cells, Auditory, Inner; Quinidine; Quinine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Recombinant Proteins; Xenopus laevis	2005
Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine. Molecular microbiology, 2007, Volume: 63, Issue:1 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Quinidine; Quinine	2007
Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine. Cardiovascular research, 2011, Mar-01, Volume: 89, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Chloroquine; Mice; Models, Molecular; Mutation; Potassium Channels, Inwardly Rectifying; Quinidine	2011
Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites. The Journal of biological chemistry, 2014, Dec-26, Volume: 289, Issue:52 Topics: Animals; Antimalarials; Binding Sites; Binding, Competitive; Biological Transport; Cells, Cultured; Chloroquine; Drug Resistance; Female; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Quinidine; Quinine; Verapamil; Xenopus laevis	2014
Recrudescence of The American journal of tropical medicine and hygiene, 2017, Volume: 96, Issue:3 Topics: Administration, Intravenous; Adult; Antimalarials; Chemoprevention; Chloroquine; Female; Gravidity; Humans; Malaria, Falciparum; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Quinidine; Recurrence; Risk Factors	2017