chloroquine and quinazolines

chloroquine has been researched along with quinazolines in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19907 (29.17)18.7374
1990's0 (0.00)18.2507
2000's3 (12.50)29.6817
2010's12 (50.00)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Schmidt, LH1
Balaraman, R; Gokhale, SV; Parikh, SH; Saibaba, P1
Cheng, CC1
Ha, SH; Shao, BR; Zhan, CQ1
Chhabra, MB; Ruprah, NS; Sanyal, PK1
Elslager, EF1
Divo, AA; Geary, TG; Jensen, JB1
Ishih, A; Miyase, T; Suzuki, T; Terada, M; Watanabe, M1
Evans, LA; Lewis, M; Lindqvist, S; Parris, A; Reynolds, A; Sharp, P; Tighe, R; Williams, MR1
Azas, N; Ducros, C; Gasquet, M; Hutter, S; Laget, M; Rathelot, P; Rault, S; Vanelle, P; Verhaeghe, P1
Byer, S; Carroll, SL; Kaza, N; Kohli, L; Lavalley, NJ; Roth, KA; Turner, KL1
Alcantara, LM; Ayong, LS; Franco, CH; Franzoi, KD; Freitas-Junior, LH; Kim, J; Lee, S; Moraes, CB1
Ling, YH; Perez-Soler, R; Piperdi, B; Schwartz, EL; Sironi, J; Zou, Y1
Fang, W; Li, A; Luo, S; Niu, X; Ruan, J; Shen, J; Tian, G; Zhao, P; Zheng, H1
Bertrand, M; Correa, RJ; DiMattia, GE; Fazio, EN; McGee, J; Peart, TM; Préfontaine, M; Shepherd, TG; Sugimoto, A; Valdes, YR1
Bokobza, SM; Devery, AM; Jiang, Y; Ryan, AJ; Weber, AM1
Chang, YT; Huang, HJ; Hwang, MH; Lin, AM; Tang, MC; Wu, MY; Yang, JC1
Bekerman, E; Einav, S1
Fan, LL; Gao, S; Li, WC; Li, XQ; Liu, JT; Sun, GP; Wang, F; Wang, H; Wei, W; Yu, HQ1
Chen, Q; Deitsch, KW; Heinberg, AR; Ukaegbu, UE; Wele, M; Zhang, X1
Chang, J; Shi, Y; Su, C; Yang, G; Zhao, L1
Shi, Y; Su, C; Zhao, L; Zheng, Y1
Chen, Y; Haase, D; Li, Y; Lu, G; Ma, Y; Nenkov, M; Petersen, I; Zhou, Z1
Bao, X; Deng, A; Li, Q; Wang, L; Wang, M; Xiang, Y; Yu, W; Zhang, B; Zhang, Y1

Reviews

1 review(s) available for chloroquine and quinazolines

ArticleYear
New perspectives on the chemotherapy of malaria, filariasis, and leprosy.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1974, Volume: 18

    Topics: Amodiaquine; Aniline Compounds; Antimalarials; Chloroquine; Cresols; Dapsone; Drug Resistance; Filariasis; Folic Acid Antagonists; Guanidines; Humans; Leprosy; Malaria; Phenethylamines; Plasmodium falciparum; Pyrrolidines; Quinazolines; Quinolines; Schiff Bases; Sulfones

1974

Other Studies

23 other study(ies) available for chloroquine and quinazolines

ArticleYear
Studies on the 2,4-diamino-6-substituted quinazolines. II. Activities of selected derivatives against infections with various drug-susceptible and drug-resistant strains of Plasmodium falciparum and Plasmodium vivax in owl monkeys.
    The American journal of tropical medicine and hygiene, 1979, Volume: 28, Issue:5

    Topics: Animals; Aotus trivirgatus; Chemical Phenomena; Chemistry; Chloroquine; Drug Resistance, Microbial; Female; Haplorhini; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinazolines

1979
Effect of acute and chronic treatment of phenobarbital and chloroquin on the turnover of 2- [2-(3-pyridyl)vinyl] -3-o-tolyl-3,4-dihydro quinazoline-4-one (SRC-909).
    Indian journal of medical sciences, 1979, Volume: 33, Issue:7

    Topics: Animals; Chloroquine; Female; Phenobarbital; Pyridines; Quinazolines; Rats

1979
Structural similarity between febrifugine and chloroquine.
    Journal of theoretical biology, 1976, Jul-07, Volume: 59, Issue:2

    Topics: Antimalarials; Chloroquine; Models, Structural; Piperidines; Quinazolines; Structure-Activity Relationship

1976
[Evaluation of the phototoxicity of five antimalarial agents and praziquantel in mice].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:3

    Topics: Animals; Antimalarials; Chloroquine; Female; Male; Mice; Naphthyridines; Photosensitivity Disorders; Praziquantel; Quinacrine; Quinazolines; Quinolines; Ultraviolet Rays

1986
Chemotherapeutic efficacy of sulphadimidine, amprolium, halofuginone and chloroquine phosphate in experimental Eimeria bareillyi coccidiosis of buffaloes.
    Veterinary parasitology, 1985, Volume: 17, Issue:2

    Topics: Amprolium; Animals; Buffaloes; Chloroquine; Coccidiosis; Coccidiostats; Eimeria; Intestine, Small; Piperidines; Quinazolines; Quinazolinones; Sulfamethazine

1985
An in vitro assay system for the identification of potential antimalarial drugs.
    The Journal of parasitology, 1983, Volume: 69, Issue:3

    Topics: Animals; Antimalarials; Cattle; Chloramphenicol; Chloroquine; Clindamycin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Piperidines; Plasmodium falciparum; Quinazolines; Quinazolinones; Rabbits

1983
Combination effects of chloroquine with the febrifugine and isofebrifugine mixture against a blood-induced infection with chloroquine-resistant Plasmodium berghei NK65 in ICR mice.
    Phytotherapy research : PTR, 2003, Volume: 17, Issue:10

    Topics: Animals; Antimalarials; Chloroquine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Malaria; Male; Mice; Mice, Inbred ICR; Parasitic Sensitivity Tests; Phytotherapy; Piperidines; Plasmodium berghei; Quinazolines

2003
Dynamic and differential regulation of NKCC1 by calcium and cAMP in the native human colonic epithelium.
    The Journal of physiology, 2007, Jul-15, Volume: 582, Issue:Pt 2

    Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Calcium; Calcium Signaling; Chloroquine; Cholinergic Agents; Colforsin; Colon; Cyclic AMP; ErbB Receptors; Humans; Intestinal Mucosa; Lysosomes; Middle Aged; Protein Synthesis Inhibitors; Quinazolines; Receptor, Muscarinic M3; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Tissue Distribution; Tyrphostins

2007
Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines.
    Bioorganic & medicinal chemistry letters, 2008, Jan-01, Volume: 18, Issue:1

    Topics: Animals; Antimalarials; Cell Line; Chloroquine; Drug Resistance; Humans; Hydrocarbons, Chlorinated; Plasmodium falciparum; Quinazolines

2008
The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells.
    Neuro-oncology, 2012, Volume: 14, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Caspases; Cell Line, Tumor; Cell Proliferation; Chloroquine; ErbB Receptors; Genes, erbB; Humans; Lysosomes; Molecular Targeted Therapy; Nerve Sheath Neoplasms; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; TOR Serine-Threonine Kinases

2012
Chemosensitization potential of P-glycoprotein inhibitors in malaria parasites.
    Experimental parasitology, 2013, Volume: 134, Issue:2

    Topics: Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Boron Compounds; Chloroquine; Chlorpheniramine; Dibenzocycloheptenes; Drug Interactions; Drug Resistance, Multiple; Erythrocytes; Fluorescent Dyes; Gefitinib; Humans; Imatinib Mesylate; Mefloquine; Piperazines; Plasmodium falciparum; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Quinolines

2013
The autophagy inhibitor chloroquine overcomes the innate resistance of wild-type EGFR non-small-cell lung cancer cells to erlotinib.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2013, Volume: 8, Issue:6

    Topics: Animals; Antimalarials; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Proliferation; Chloroquine; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Flow Cytometry; Humans; Lung Neoplasms; Mice; Mice, Nude; Protein Kinase Inhibitors; Quinazolines; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2013
Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma.
    British journal of cancer, 2013, Jul-09, Volume: 109, Issue:1

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 7; Beclin-1; Cell Line, Tumor; Cell Survival; Chloroquine; ErbB Receptors; Glioblastoma; Humans; Membrane Proteins; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-ret; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; TOR Serine-Threonine Kinases; Ubiquitin-Activating Enzymes; Xenograft Model Antitumor Assays

2013
Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability.
    Carcinogenesis, 2014, Volume: 35, Issue:9

    Topics: Allosteric Regulation; Antineoplastic Agents; Ascites; Autophagy; Benzylamines; Cell Line, Tumor; Cell Survival; Chloroquine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Inhibitory Concentration 50; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Quinazolines; Quinoxalines; Spheroids, Cellular

2014
Combining AKT inhibition with chloroquine and gefitinib prevents compensatory autophagy and induces cell death in EGFR mutated NSCLC cells.
    Oncotarget, 2014, Jul-15, Volume: 5, Issue:13

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Drug Synergism; ErbB Receptors; Female; Gefitinib; Heterocyclic Compounds, 3-Ring; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Mutation; Proto-Oncogene Proteins c-akt; Quinazolines; RNA Interference; Xenograft Model Antitumor Assays

2014
Chloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Adenine; Antineoplastic Agents; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chloroquine; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Quinazolines

2015
Infectious disease. Combating emerging viral threats.
    Science (New York, N.Y.), 2015, Apr-17, Volume: 348, Issue:6232

    Topics: Adenine; Adenosine; Antiviral Agents; Benzamides; Chloroquine; Communicable Diseases, Emerging; Cyclosporins; Cytosine; Dengue; Drug Approval; Drug Design; Erlotinib Hydrochloride; Hemorrhagic Fever, Ebola; Humans; Imatinib Mesylate; Indoles; Organophosphonates; Piperazines; Purine Nucleosides; Pyrimidines; Pyrroles; Pyrrolidines; Quinazolines; Sunitinib; Viruses

2015
Autophagy Inhibition Overcomes the Antagonistic Effect Between Gefitinib and Cisplatin in Epidermal Growth Factor Receptor Mutant Non--Small-Cell Lung Cancer Cells.
    Clinical lung cancer, 2015, Volume: 16, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chloroquine; Cisplatin; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Mutation; Protein Kinase Inhibitors; Quinazolines

2015
A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum.
    PLoS genetics, 2015, Volume: 11, Issue:5

    Topics: Antigenic Variation; Antigens, Protozoan; Azepines; Chloroquine; Gene Expression Regulation; Genetic Loci; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Hydroxamic Acids; Immune Evasion; Inhibitory Concentration 50; Malaria, Falciparum; Models, Theoretical; Piperazines; Plasmodium falciparum; Promoter Regions, Genetic; Protozoan Proteins; Quinazolines; RNA Polymerase II; Terpenes; Transcriptional Activation; Transcriptome

2015
Co-delivery of Gefitinib and chloroquine by chitosan nanoparticles for overcoming the drug acquired resistance.
    Journal of nanobiotechnology, 2015, Sep-22, Volume: 13

    Topics: Adenosine Triphosphate; Annexin A5; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Chitosan; Chloroquine; Drug Delivery Systems; Drug Resistance, Neoplasm; Endocytosis; Fluorescein-5-isothiocyanate; Gefitinib; Humans; Intracellular Space; Nanoparticles; Necrosis; Quinazolines

2015
mAb MDR1-modified chitosan nanoparticles overcome acquired EGFR-TKI resistance through two potential therapeutic targets modulation of MDR1 and autophagy.
    Journal of nanobiotechnology, 2017, Oct-04, Volume: 15, Issue:1

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autophagy; Cell Line, Tumor; Chitosan; Chloroquine; Drug Delivery Systems; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Nanoparticles; Neoplasms; Protein Kinase Inhibitors; Quinazolines

2017
Growth inhibitory role of the p53 activator SCH 529074 in non‑small cell lung cancer cells expressing mutant p53.
    Oncology reports, 2020, Volume: 43, Issue:6

    Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lung Neoplasms; Mutation; Piperazines; Quinazolines; Signal Transduction; Tumor Suppressor Protein p53

2020
BIX-01294-enhanced chemosensitivity in nasopharyngeal carcinoma depends on autophagy-induced pyroptosis.
    Acta biochimica et biophysica Sinica, 2020, Oct-19, Volume: 52, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Autophagy-Related Protein 5; Azepines; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Survival; Chloroquine; Cisplatin; CRISPR-Cas Systems; Gene Knockout Techniques; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Pyroptosis; Quinazolines; Receptors, Estrogen; Signal Transduction

2020