chloroquine has been researched along with pyrroles in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 13 (54.17) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hussain Qadri, SM; Williams, RP | 1 |
| Galambos, JT; Olansky, S; Vogler, WR | 1 |
| Colwell, WT; Henry, DW; Lange, JH | 1 |
| Abud-Mendoza, C; Baranda, L; Cruz-Rizo, J; Cuevas-Orta, E; de la Fuente, H; González-Amaro, R | 1 |
| DOWDLE, EB; EALES, L; SAUNDERS, SJ; SWEENEY, GD | 1 |
| Ausseil, F; Debitus, C; Duigou, AG; Guella, G; Mancini, I; Menou, JL; Pietra, F; Sauvain, M | 1 |
| Kang, SK; Kim, CH; Kim, YH; Park, YG | 1 |
| Basilico, N; Brun, R; Casagrande, M; Parapini, S; Sparatore, A; Sparatore, F; Taramelli, D; Wittlin, S | 1 |
| Davis, TM; Wong, RP | 1 |
| Brun, R; Davies, J; Kaiser, M; Lander, H; Leung, SC; O'Neill, PM; Pacorel, B; Stachulski, AV; Vivas, L; Ward, SA | 1 |
| Almeras, L; Amalvict, R; Baret, E; Briolant, S; Gil, M; Henry, M; Parquet, V; Pradines, B; Rogier, C; Wurtz, N | 1 |
| Kay, LE; Ruschak, AM; Schimmer, AD; Slassi, M | 1 |
| Crafter, C; Davies, BR; Gleave, ME; Kumano, M; Lamoureux, F; Thomas, C; Zhang, F; Zoubeidi, A | 1 |
| Lamoureux, F; Zoubeidi, A | 1 |
| Charman, SA; Gilbert, IH; Kaiser, M; Murugesan, D; Norval, S; Read, KD; Riley, J; White, KL; Wyatt, PG; Yeates, C | 1 |
| Abdel-Aziz, AK; Abdel-Naim, AB; El-Demerdash, E; Elgendy, M; Shouman, S | 1 |
| Chang, ZY; Fei, HR; Sun, BL; Wang, FZ; Yang, MF; Yang, XY | 1 |
| Chen, S; Cui, L; Cui, X; Edwards, H; Ge, Y; Wang, G | 1 |
| Bekerman, E; Einav, S | 1 |
| Abraham, RT; Bray, K; Cochran, N; De Jesus, R; Eng, CH; Fantin, VR; Fitzgerald, SL; Frias, E; George, E; Hoffman, GR; Lemon, L; Liu, S; Lucas, J; McAllister, G; Murphy, LO; Nyfeler, B; Tkach, D; Toral-Barza, L; Ugwonali, S; Wang, Z | 1 |
| Agnamey, P; Azas, N; Bentzinger, G; Cohen, A; Dassonville-Klimpt, A; Guillon, J; Hutter, S; Jonet, A; Moreau, S; Mullie, C; Savrimoutou, S; Schneider, J; Sonnet, P; Taudon, N | 1 |
| Bananis, E; Chen, C; Curtis, JR; Fan, H; Hirose, T; Lindsey, S; Mendelsohn, AM; Nduaka, CI; Tanaka, Y; Valdez, H; Wang, L; Winthrop, KL; Yamaoka, K | 1 |
| Edemir, B; Kaiser, M | 1 |
| Brügel, M; Habler, K; Liebchen, U; Paal, M; Scharf, C; Schönermarck, U; Teupser, D; Vogeser, M | 1 |
1 review(s) available for chloroquine and pyrroles
| Article | Year |
|---|---|
Novel proteasome inhibitors to overcome bortezomib resistance.
Topics: Allosteric Site; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Chloroquine; Clioquinol; Drug Resistance, Neoplasm; Humans; Hydroxyquinolines; Lactones; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Threonine; Ubiquitinated Proteins; Ubiquitination | 2011 |
1 trial(s) available for chloroquine and pyrroles
| Article | Year |
|---|---|
Therapy with statins in patients with refractory rheumatic diseases: a preliminary study.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Atorvastatin; Biomarkers; Blood Sedimentation; C-Reactive Protein; Child; Chloroquine; Dose-Response Relationship, Drug; Granulomatosis with Polyangiitis; Heptanoic Acids; HLA-DR Antigens; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukocytes, Mononuclear; Lupus Erythematosus, Systemic; Middle Aged; Proteinuria; Pyrroles; Rheumatic Diseases; Rheumatic Fever; Simvastatin; Treatment Outcome | 2003 |
22 other study(ies) available for chloroquine and pyrroles
| Article | Year |
|---|---|
Biosynthesis of the tripyrrole bacterial pigment, prodigiosin, by nonproliferating cells of Serratia marcescens.
Topics: Amino Acids; Anti-Bacterial Agents; Carbon Isotopes; Cell Count; Chloramphenicol; Chloroquine; Cycloheximide; Dactinomycin; Fluorouracil; Kinetics; Mitomycins; Pigments, Biological; Prodigiosin; Proteins; Puromycin; Pyrroles; Serratia marcescens; Streptomycin; Temperature; Tryptophan | 1972 |
Biochemical effects of chloroquine therapy in porphyria cutanea tarda.
Topics: Ascites; Body Temperature; Chemical and Drug Induced Liver Injury; Chloroquine; Chromatography; Feces; Female; Hematologic Diseases; Humans; Iron; Levulinic Acids; Liver Function Tests; Male; Middle Aged; Porphyrias; Porphyrins; Propionates; Pyrroles; Time Factors | 1970 |
Chemotherapeutic nitroheterocycles. Nitropyrrole-2-carboxaldehyde derivatives.
Topics: Aldehydes; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Bacteria; Chloroquine; Elements; Fungi; Mice; Pyrroles; Quinine | 1968 |
EFFECTS OF CHLOROQUINE ON PATIENTS WITH CUTANEOUS PORPHYRIA OF THE "SYMPTOMATIC" TYPE.
Topics: Amino Acids; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chloroquine; Classification; Clinical Enzyme Tests; Fluids and Secretions; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Hepatitis; Humans; Levulinic Acids; Liver; Metabolism; Pathology; Porphyrias; Porphyrins; Pyrroles; Toxicology; Urine | 1965 |
New 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidinium alkaloids (phloeodictynes) from the New Caledonian shallow-water haplosclerid sponge Oceanapia fistulosa. Structural elucidation from mainly LC-tandem-MS-soft-ionization techniques and discovery of antiplas
Topics: Alkaloids; Animals; Antimalarials; Cell Line, Tumor; Cell Survival; Chloroquine; Chromatography, Liquid; Humans; Molecular Structure; New Caledonia; Parasitic Sensitivity Tests; Plasmodium falciparum; Porifera; Pyridinium Compounds; Pyrroles; Spectrometry, Mass, Electrospray Ionization | 2004 |
cAMP-PKA signaling pathway regulates bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts.
Topics: Animals; Antibodies; Bone Resorption; Carbazoles; Cathepsin K; Cathepsins; Cells, Cultured; Chloroquine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Lysosomes; Mannose; Mice; Monensin; Naphthalenes; Osteoclasts; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrroles; Receptor, IGF Type 2; Signal Transduction; Sulfonamides | 2006 |
Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline.
Topics: Aminoquinolines; Animals; Antimalarials; Body Weight; Cell Line; Chloroquine; Humans; Malaria; Mice; Microsomes; Models, Chemical; Plasmodium berghei; Plasmodium falciparum; Pyrroles | 2008 |
Statins as potential antimalarial drugs: low relative potency and lack of synergy with conventional antimalarial drugs.
Topics: Animals; Antimalarials; Atorvastatin; Chloroquine; Culture Media; Drug Resistance; Drug Synergism; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrroles | 2009 |
Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Inhibitory Concentration 50; Morpholines; Piperazine; Piperazines; Plasmodium falciparum; Pyrroles; Structure-Activity Relationship | 2010 |
Synergy of mefloquine activity with atorvastatin, but not chloroquine and monodesethylamodiaquine, and association with the pfmdr1 gene.
Topics: Amodiaquine; Antimalarials; Atorvastatin; Chloroquine; DNA, Protozoan; Drug Synergism; Gene Dosage; Genotype; Heptanoic Acids; Humans; Inhibitory Concentration 50; Mefloquine; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrroles | 2010 |
Blocked autophagy using lysosomotropic agents sensitizes resistant prostate tumor cells to the novel Akt inhibitor AZD5363.
Topics: Autophagy; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chloroquine; Drug Resistance, Neoplasm; Drug Synergism; Humans; Lysosomes; Male; Oncogene Protein v-akt; Prostatic Neoplasms; PTEN Phosphohydrolase; Pyrimidines; Pyrroles; Signal Transduction | 2013 |
Dual inhibition of autophagy and the AKT pathway in prostate cancer.
Topics: Adenine; Autophagy; Cell Line, Tumor; Chloroquine; Clinical Trials, Phase I as Topic; Humans; Macrolides; Male; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Signal Transduction | 2013 |
Structure-activity relationship studies of pyrrolone antimalarial agents.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Half-Life; Mice; Microsomes, Liver; Plasmodium falciparum; Pyrimethamine; Pyrroles; Structure-Activity Relationship | 2013 |
Chloroquine synergizes sunitinib cytotoxicity via modulating autophagic, apoptotic and angiogenic machineries.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caco-2 Cells; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Survival; Chloroquine; Drug Synergism; Female; HCT116 Cells; HeLa Cells; Hep G2 Cells; Humans; Immunohistochemistry; Indoles; MCF-7 Cells; Mice; Neovascularization, Pathologic; Pyrroles; Sunitinib | 2014 |
CCT128930 induces cell cycle arrest, DNA damage, and autophagy independent of Akt inhibition.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Proliferation; Chloroquine; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; G1 Phase Cell Cycle Checkpoints; Hep G2 Cells; Histones; Humans; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Signal Transduction | 2014 |
Combination of chloroquine and GX15-070 (obatoclax) results in synergistic cytotoxicity against pancreatic cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; bcl-X Protein; Cell Line, Tumor; Chloroquine; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Indoles; Myeloid Cell Leukemia Sequence 1 Protein; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrroles | 2014 |
Infectious disease. Combating emerging viral threats.
Topics: Adenine; Adenosine; Antiviral Agents; Benzamides; Chloroquine; Communicable Diseases, Emerging; Cyclosporins; Cytosine; Dengue; Drug Approval; Drug Design; Erlotinib Hydrochloride; Hemorrhagic Fever, Ebola; Humans; Imatinib Mesylate; Indoles; Organophosphonates; Piperazines; Purine Nucleosides; Pyrimidines; Pyrroles; Pyrrolidines; Quinazolines; Sunitinib; Viruses | 2015 |
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy.
Topics: Antineoplastic Agents; Autophagy; Autophagy-Related Protein 7; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chloroquine; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Gene Knockout Techniques; Humans; Indoles; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Pyrroles; Radiation Tolerance; Sunitinib; Ubiquitin-Activating Enzymes | 2016 |
Synthesis and Antimalarial Activity of New Enantiopure Aminoalcoholpyrrolo[ 1,2-a]quinoxalines.
Topics: Amino Alcohols; Animals; Antimalarials; Cell Line, Tumor; Chloroquine; CHO Cells; Cricetulus; Humans; Mefloquine; Plasmodium falciparum; Pyrroles; Quinoxalines; Stereoisomerism | 2018 |
Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Clinical Trials as Topic; Databases, Factual; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucocorticoids; Herpes Zoster; Humans; Incidence; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Multivariate Analysis; Piperidines; Proportional Hazards Models; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Risk Factors | 2017 |
Lithium Chloride and GSK3 Inhibition Reduce Aquaporin-2 Expression in Primary Cultured Inner Medullary Collecting Duct Cells Due to Independent Mechanisms.
Topics: Animals; Aquaporin 2; Aquaporin 3; Aquaporin 4; Cells, Cultured; Chloroquine; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Female; Glycogen Synthase Kinase 3; Indoles; Kidney Tubules, Collecting; Leupeptins; Lithium Chloride; Macrolides; Maleimides; Protein Kinase Inhibitors; Proteolysis; Pyrimidines; Pyrroles; Rats, Wistar; RNA, Messenger | 2020 |
Simultaneous quantification of seven repurposed COVID-19 drugs remdesivir (plus metabolite GS-441524), chloroquine, hydroxychloroquine, lopinavir, ritonavir, favipiravir and azithromycin by a two-dimensional isotope dilution LC-MS/MS method in human serum
Topics: Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Azithromycin; Chloroquine; Chromatography, Liquid; COVID-19; COVID-19 Drug Treatment; Furans; Humans; Hydroxychloroquine; Isotopes; Lopinavir; Pandemics; Pyrazines; Pyrroles; Ritonavir; SARS-CoV-2; Tandem Mass Spectrometry; Triazines | 2021 |