chloroquine has been researched along with promethazine in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (22.22) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 13 (48.15) | 29.6817 |
| 2010's | 6 (22.22) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Alibert, S; Barbe, J; Houdoin, C; Karolak-Wojciechowska, J; Parzy, D; Pradines, B; Santelli-Rouvier, C | 1 |
| Elshorst, B; Fiebig, K; Griesinger, C; Grimme, S; Jacobs, DM; Vogtherr, M; Zahn, R | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL | 1 |
| Coudert, B; Dwyer, TM; Joshi, UM; Kodavanti, PR; Mehendale, HM | 1 |
| Fukao, T; Takagi, K | 1 |
| Byles, AB; D'sa, A | 1 |
| Petreniuk, LM | 1 |
| Drescher, JJ; Song, CW; Tabachnick, J | 1 |
| de Freudenreich, J; Duckert, A; Fabre, J; Pitton, JS; Rudhardt, M; Virieux, C | 1 |
| Brewer, TG; Gerena, L; Kyle, DE; Milhous, WK; Oduola, AM; Rossan, RN; Salako, LA; Schuster, BG; Sowunmi, A | 1 |
| Akinboye, DO; Falade, CO; Gbotosho, GO; Happi, TC; Oduola, AM; Oduola, OO; Ogundahunsi, OA; Sowunmi, A | 1 |
| Ajayi, AA; Kolawole, BA; Udoh, SJ | 1 |
| Gbotosho, GO; Gerena, L; Happi, CT; Kyle, DE; Milhous, WK; Oduola, AM; Ogundahunsi, OA; Salako, LA; Sowunmi, A | 1 |
| Gbotosho, GO; Happi, CT; Oduola, AM; Ogundahunsi, OA; Sijuade, A; Sowunmi, A | 1 |
| Ganiyu, A; Gbotosho, GO; Happi, CT; Oduola, AM; Ogundahunsi, OA; Sowunmi, A | 1 |
2 review(s) available for chloroquine and promethazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization | 2021 |
3 trial(s) available for chloroquine and promethazine
| Article | Year |
|---|---|
Reduction of reaction due to iron dextran infusion using chloroquine.
Topics: Anemia; Chloroquine; Female; Humans; Iron-Dextran Complex; Malaria; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Hematologic; Promethazine; Tanzania | 1970 |
Endogenous opioids, mu-opiate receptors and chloroquine-induced pruritus: a double-blind comparison of naltrexone and promethazine in patients with malaria fever who have an established history of generalized chloroquine-induced itching.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Antipruritics; Area Under Curve; Chloroquine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Naltrexone; Opioid Peptides; Parasitemia; Plasmodium; Promethazine; Pruritus; Receptors, Opioid, mu; Time Factors | 2004 |
Comparative study of interactions between chloroquine and chlorpheniramine or promethazine in healthy volunteers: a potential combination-therapy phenomenon for resuscitating chloroquine for malaria treatment in Africa.
Topics: Adult; Animals; Antimalarials; Area Under Curve; Chloroquine; Chlorpheniramine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Promethazine | 2008 |
22 other study(ies) available for chloroquine and promethazine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Synthesis and effects on chloroquine susceptibility in Plasmodium falciparum of a series of new dihydroanthracene derivatives.
Topics: Animals; Anthracenes; Antimalarials; Chloroquine; CHO Cells; Cricetinae; Drug Resistance, Multiple; Erythrocytes; In Vitro Techniques; Models, Molecular; Plasmodium falciparum; Structure-Activity Relationship | 2002 |
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein.
Topics: Antimalarials; Binding Sites; Chloroquine; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Peptide Fragments; Phenothiazines; Prions; Protein Structure, Secondary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship | 2003 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Types of interaction of amphiphilic drugs with phospholipid vesicles.
Topics: Amiodarone; Anilino Naphthalenesulfonates; Binding Sites; Chloramphenicol; Chloroquine; Chlorpromazine; Diphenylhexatriene; Imipramine; Lipidoses; Lung Diseases; Membrane Lipids; Phospholipids; Promethazine; Propranolol; Surface-Active Agents; Trimipramine | 1988 |
Effects of some drugs on capillary permeability in the anaphylaxis of the mouse.
Topics: Aminopyrine; Anaphylaxis; Animals; Anti-Inflammatory Agents; Antilymphocyte Serum; Aprotinin; Aspirin; Body Temperature; Capillary Permeability; Chloroquine; Chlorpromazine; Cortisone; Cyclizine; Depression, Chemical; Desensitization, Immunologic; Diphenhydramine; Epinephrine; Female; Glycyrrhiza; Histamine H1 Antagonists; Indomethacin; Mice; Oxyphenbutazone; Phenylbutazone; Plants, Medicinal; Promethazine; Rectum; Reserpine; Splenectomy; Triprolidine | 1971 |
[Treatment of chronic acquired toxoplasmosis].
Topics: Ascorbic Acid; Chloroquine; Chronic Disease; Humans; Prednisolone; Promethazine; Pyrimethamine; Sulfamethazine; Toxoplasmosis; Vitamins | 1971 |
Effect of anti-inflammatory compounds on beta-irradiation-induced increase in vascular peremeability.
Topics: Aminocaproates; Animals; Anti-Inflammatory Agents; Biological Transport; Blood Proteins; Blood Vessels; Chloroquine; Guinea Pigs; Indomethacin; Male; ortho-Aminobenzoates; Permeability; Promethazine; Radiation Effects; Serum Albumin, Radio-Iodinated; Skin; Triamcinolone | 1968 |
Influence of renal insufficiency on the excretion of chloroquine, phenobarbital, phenothiazines and methacycline.
Topics: Adult; Aged; Chloroquine; Chlorpromazine; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Methacycline; Middle Aged; Phenobarbital; Promethazine; Spectrophotometry; Ultraviolet Rays | 1967 |
In vitro and in vivo reversal of chloroquine resistance in Plasmodium falciparum with promethazine.
Topics: Adult; Animals; Antimalarials; Antipruritics; Aotidae; Aotus trivirgatus; Chloroquine; Disease Models, Animal; Drug Resistance; Drug Synergism; Humans; Malaria, Falciparum; Plasmodium falciparum; Promethazine | 1998 |
Plasmodium berghei: efficacy and safety of combinations of chloroquine and promethazine in chloroquine resistant infections in gravid mice.
Topics: Animals; Antimalarials; Birth Weight; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Gravidity; Malaria; Male; Mice; Parturition; Plasmodium berghei; Pregnancy; Pregnancy Complications, Parasitic; Promethazine | 2004 |
The effects of alpha1-acid glycoprotein on the reversal of chloroquine resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Calcium Channel Blockers; Chloroquine; Chlorpheniramine; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Enzyme Inhibitors; Histamine H1 Antagonists; Orosomucoid; Plasmodium falciparum; Promethazine; Verapamil | 2006 |
Potential contribution of prescription practices to the emergence and spread of chloroquine resistance in south-west Nigeria: caution in the use of artemisinin combination therapy.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Histamine Antagonists; Humans; Malaria, Falciparum; Nigeria; Practice Patterns, Physicians'; Promethazine; Retrospective Studies | 2009 |