chloroquine and pi103

chloroquine has been researched along with pi103 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, Y; Feng, F; He, S; Jiang, X; Li, Q; Lu, X; Qu, W; Sun, H1
Davis, DP; De Mazière, A; Degtyarev, M; Friedman, LS; Gray, DC; Hoeflich, KP; Klumperman, J; Lee, BB; Lin, J; Lin, K; Murray, LJ; Orr, C; Prior, WW; Stern, HM; Tien, JY; van Dijk, S; Wu, H1
Cheng, C; Debnath, J; Fan, QW; Feldman, M; Haas-Kogan, D; Hackett, C; Houseman, BT; James, CD; Nicolaides, T; Oakes, SA; Shokat, KM; Weiss, WA1
Debatin, KM; Enzenmüller, S; Fulda, S; Gonzalez, P1

Reviews

1 review(s) available for chloroquine and pi103

ArticleYear
Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy.
    Journal of medicinal chemistry, 2018, 06-14, Volume: 61, Issue:11

    Topics: Animals; Autophagy; Drug Design; Humans; Small Molecule Libraries

2018

Other Studies

3 other study(ies) available for chloroquine and pi103

ArticleYear
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents.
    The Journal of cell biology, 2008, Oct-06, Volume: 183, Issue:1

    Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Protein 7; Benzylamines; Cell Cycle; Cell Line, Tumor; Chloroquine; Drug Interactions; Female; Furans; Humans; Lysosomes; Macrolides; Mice; Mice, Nude; Mitochondria; Mutation; Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proton-Translocating ATPases; PTEN Phosphohydrolase; Pyridines; Pyrimidines; Quinoxalines; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Ubiquitin-Activating Enzymes; Xenograft Model Antitumor Assays

2008
Akt and autophagy cooperate to promote survival of drug-resistant glioma.
    Science signaling, 2010, Nov-09, Volume: 3, Issue:147

    Topics: Animals; Autophagy; Cell Line, Tumor; Chloroquine; Drug Synergism; Flow Cytometry; Furans; Glioma; Histological Techniques; Humans; Imidazoles; Immunoblotting; Immunohistochemistry; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Mitochondria; Mutation; Oncogene Protein v-akt; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Pyridines; Pyrimidines; Quinolines; Sirolimus; TOR Serine-Threonine Kinases; Transplantation, Heterologous

2010
Chloroquine overcomes resistance of lung carcinoma cells to the dual PI3K/mTOR inhibitor PI103 by lysosome-mediated apoptosis.
    Anti-cancer drugs, 2013, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cathepsin B; Cell Line, Tumor; Cell Survival; Chloroquine; Drug Resistance, Neoplasm; Furans; Humans; Intracellular Membranes; Lung Neoplasms; Lysosomal-Associated Membrane Protein 1; Lysosomes; Permeability; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Pyrimidines; TOR Serine-Threonine Kinases; Up-Regulation

2013