chloroquine and phenobarbital

chloroquine has been researched along with phenobarbital in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (36.11)	18.7374
1990's	4 (11.11)	18.2507
2000's	9 (25.00)	29.6817
2010's	10 (27.78)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Bray, PG; Johnson, DJ; Owen, A; Plant, N; Ward, SA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Sen, S; Sinha, N	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Balaraman, R; Gokhale, SV; Parikh, SH; Saibaba, P	1
Bhutani, LK; Bikhchandani, R; Deshpande, SG; Kandhari, KC; Narang, BS	1
Amabeoku, G	1
Howells, RE; Ndifor, AM; Ward, SA	1
Niitani, H	1
Edwards, A; Gupta, JD; Harley, JD	1
Hasegawa, AT; Peterson, RE; Roerig, DL; Wang, RI	1
Banez, RJ; Combs, HF; Decker, WJ; Treuting, JJ	1
Stanfield, JP	1
de Freudenreich, J; Duckert, A; Fabre, J; Pitton, JS; Rudhardt, M; Virieux, C	1
Back, DJ; Sutcliffe, F; Tjia, JF	1
Dada, OA; Martins, OO	1
Karthikeyan, G; Padmanaban, G; Surolia, N	1
Awasthi, A; Bhakuni, V; Dutta, GP; Levy, HB; Maheshwari, RK; Mehrotra, S	1
BOTTIROLI, JA; ROSENBERG, FJ	1
MITCHELL, CL	1

Reviews

1 review(s) available for chloroquine and phenobarbital

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

35 other study(ies) available for chloroquine and phenobarbital

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
Drug-regulated expression of Plasmodium falciparum P-glycoprotein homologue 1: a putative role for nuclear receptors. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4 Topics: Animals; Anticonvulsants; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Drug Resistance; Gene Expression Regulation; Humans; Parasitic Sensitivity Tests; Phenobarbital; Plasmodium falciparum; Protozoan Proteins; Receptors, Cytoplasmic and Nuclear	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1 Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances. IARC monographs on the evaluation of the carcinogenic risk of chemicals to man, 1977, Volume: 13 Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; Ethionamide; Female; Humans; Hycanthone; Male; Metronidazole; Neoplasms; Neoplasms, Experimental; Oxazepam; Oxymetholone; Oxyphenbutazone; Oxyquinoline; Phenacetin; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Pyrimethamine; Risk	1977
Effect of acute and chronic treatment of phenobarbital and chloroquin on the turnover of 2- [2-(3-pyridyl)vinyl] -3-o-tolyl-3,4-dihydro quinazoline-4-one (SRC-909). Indian journal of medical sciences, 1979, Volume: 33, Issue:7 Topics: Animals; Chloroquine; Female; Phenobarbital; Pyridines; Quinazolines; Rats	1979
Study of the effects of certain drugs on experimental porphyria in rats. Dermatologica, 1977, Volume: 154, Issue:5 Topics: Animals; Chloroquine; Dicarbethoxydihydrocollidine; Ethanol; Griseofulvin; Liver; Phenobarbital; Porphyrias; Porphyrins; Rats; Time Factors	1977
Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice. General pharmacology, 1992, Volume: 23, Issue:2 Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Chloroquine; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Phenobarbital; Seizures	1992
Cytochrome P-450 activity in malarial parasites and its possible relationship to chloroquine resistance. Molecular and biochemical parasitology, 1990, Volume: 41, Issue:2 Topics: 7-Alkoxycoumarin O-Dealkylase; Aminopyrine N-Demethylase; Animals; Chloroquine; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance; Enzyme Induction; Kinetics; Phenobarbital; Plasmodium berghei; Plasmodium falciparum; Spectrum Analysis	1990
[Current usage of antineoplastic agents]. Naika. Internal medicine, 1971, Volume: 27, Issue:6 Topics: Antineoplastic Agents; Bronchial Neoplasms; Chloroquine; Chymotrypsin; Cyclophosphamide; Female; Fibrinolysin; Fibrinolytic Agents; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycins; Phenobarbital; Serotonin; Trypsin	1971
Photomicrographic evaluation of drug-induced cataracts in cultured embryonic chick lens. Experimental eye research, 1973, Volume: 15, Issue:4 Topics: Animals; Cataract; Chick Embryo; Chloroquine; Culture Media; Culture Techniques; Hydroquinones; Lens, Crystalline; Naphthols; Naphthoquinones; Ouabain; Phenacetin; Phenobarbital; Phenylbutazone; Phenylhydrazines; Photomicrography; Prednisolone; Primaquine; Pyrogallol; Sulfanilamides; Vitamin K	1973
Effect of chloroquine and phenobarbital on morphine glucuronidation and biliary excretion in the rat. Biochemical pharmacology, 1974, Apr-15, Volume: 23, Issue:8 Topics: Animals; Bile; Carbon Radioisotopes; Catheterization; Chloroquine; Glucuronates; Injections, Intravenous; Male; Morphine; Phenobarbital; Rats; Time Factors	1974
Dialysis of drugs against activated charcoal. Toxicology and applied pharmacology, 1971, Volume: 18, Issue:3 Topics: Adsorption; Amitriptyline; Aspirin; Charcoal; Chlordiazepoxide; Chloroquine; Dextroamphetamine; Dextropropoxyphene; Dialysis; Diazepam; Glutethimide; Meprobamate; Methaqualone; Models, Biological; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Salicylates; Secobarbital; Time Factors	1971
Fever in children in the tropics. British medical journal, 1969, Mar-22, Volume: 1, Issue:5646 Topics: Anti-Bacterial Agents; Aspirin; Child; Child, Preschool; Chloroquine; Fever; Humans; Hypothermia; Phenobarbital; Seizures; Steroids; Tropical Medicine	1969
Influence of renal insufficiency on the excretion of chloroquine, phenobarbital, phenothiazines and methacycline. Helvetica medica acta, 1967, Volume: 33, Issue:4 Topics: Adult; Aged; Chloroquine; Chlorpromazine; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Methacycline; Middle Aged; Phenobarbital; Promethazine; Spectrophotometry; Ultraviolet Rays	1967
Tolbutamide as a model drug for the study of enzyme induction and enzyme inhibition in the rat. British journal of pharmacology, 1984, Volume: 81, Issue:3 Topics: Animals; Chloroquine; Cimetidine; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Kinetics; Male; Phenobarbital; Primaquine; Rats; Rats, Inbred Strains; Substrate Specificity; Tolbutamide	1984
Drug effects on the intestinal absorption of estrogens. Journal of steroid biochemistry, 1983, Volume: 19, Issue:1C Topics: Analgesics; Animals; Anti-Bacterial Agents; Antimalarials; Ascorbic Acid; Chloroquine; Diet; Estrogens; Ethanol; Humans; Intestinal Absorption; Pharmacology; Phenobarbital	1983
Involvement of cytochrome P-450 in conferring chloroquine resistance to the malarial parasite, Plasmodium falciparum. Biochemical and biophysical research communications, 1993, Dec-15, Volume: 197, Issue:2 Topics: Animals; Chloroquine; Cloning, Molecular; Cytochrome P-450 Enzyme System; Drug Resistance; Exons; Methionine; Phenobarbital; Plasmodium falciparum; Rats; RNA, Messenger; RNA, Protozoan	1993
Poly ICLC enhances the antimalarial activity of chloroquine against multidrug-resistant Plasmodium yoelii nigeriensis in mice. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 1997, Volume: 17, Issue:7 Topics: Animals; Antimalarials; Carboxymethylcellulose Sodium; Chloroquine; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Drug Therapy, Combination; Enzyme Induction; Interferon Inducers; Mice; Phenobarbital; Plasmodium yoelii; Poly I-C; Polylysine	1997
ANTIMALARIALS AND OTHER ANTICONVULSANT DRUGS: PREDICTIVE VALIDITY OF LABORATORY TESTS. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115 Topics: Animals; Anticonvulsants; Antimalarials; Chloroquine; Electric Stimulation; Hydroxychloroquine; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Quinacrine; Research; Seizures	1964
THE ABSENCE OF ANTICONVULSANT PROPERTIES OF QUINACRINE AND CHLOROQUINE IN MICE. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116 Topics: Anticonvulsants; Chloroquine; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Quinacrine; Research; Seizures; Toxicology	1964