chloroquine and pentamidine

chloroquine has been researched along with pentamidine in 88 studies

Research

Studies (88)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (5.68)	18.7374
1990's	1 (1.14)	18.2507
2000's	40 (45.45)	29.6817
2010's	40 (45.45)	24.3611
2020's	2 (2.27)	2.80

Authors

Authors	Studies
Bailey, BN; Caldera, A; Croft, SL; Docampo, R; Grimley, JS; Heath, HT; Kendrick, H; Lewis, JC; Lira, R; Martin, MB; Moreno, SN; Oldfield, E; Urbina, JA; Yardley, V	1
Chibale, K; Croft, SL; Fairlamb, AH; Haupt, H; Kendrick, H; Saravanamuthu, A; Yardley, V	1
Croft, SL; del Rayo Camacho, M; Kirby, GC; Marley, D; Phillipson, JD; Warhurst, DC	1
Dunbar, DC; Ferreira, D; Jacob, MR; Li, XC; Muhammad, I; Tekwani, BL	1
Hamann, MT; Mesecar, AD; Rao, KV; Santarsiero, BD; Schinazi, RF; Tekwani, BL	1
Bedir, E; Dunbar, DC; Ferreira, D; Khan, SI; Muhammad, I; Takamatsu, S; Tekwani, BL; Walker, LA	1
Avery, MA; Bandyopadhyaya, AK; Desai, PV; Furtado, MM; Muraleedharan, KM; Tekwani, BL	1
Avery, MA; Choi, SR; Labadie, GR	1
Cushion, MT; Huang, TL; Krogstad, DJ; Krogstad, FM; Mayence, A; Vanden Eynde, JJ	1
Bedir, E; Khan, IA; Khan, SI; Muhammad, I; Pelletier, J; Takamatsu, S; Tekwani, BL; Walker, LA	1
Hamann, MT; Kasanah, N; Rao, KV; Schinazi, RF; Tekwani, BL; Wahyuono, S	1
Avery, M; Desai, PV; Gut, J; Patny, A; Rosenthal, P; Sabnis, Y; Srivastava, A; Tekwani, B	1
Bauer, H; Davioud-Charvet, E; Krauth-Siegel, RL; Lee, B; Melchers, J; Rattray, L; Ruppert, T; Yardley, V	1
Alvarez, A; Atherton, R; Coro, J; Little, S; Pérez, R; Rodríguez, H; Súarez, M; Wharton, H; Yardley, V	1
Alonso, D; Donia, MS; Franzblau, SG; Garcia-Palomero, E; Hamann, MT; Khan, SI; Martinez, A; Medina, M; Peng, J; Rao, KV; Tekwani, BL; Wahyuono, S; Willett, KL	1
Croft, SL; Gilbert, IH; Gonzalez-Pacanowska, D; Gros, L; Jimenez, CJ; Little, S; Lorente, SO; Rattray, L; Ruiz-Perez, LM; Wharton, H; Yardley, V	1
Bharate, SB; Chauthe, SK; Jacob, MR; Khan, IA; Khan, SI; Singh, IP; Tekwani, BL; Yunus, NA	1
Jacob, MR; Jain, M; Jain, R; Kaur, K; Khan, SI; Patel, SR; Patil, P; Tekwani, BL	1
Ablordeppey, SY; Fan, P; Jacob, M; Khan, A; Khan, S; Li, S; Mardenborough, LG; Walker, L; Zhang, W; Zhu, XY	1
Barszcz, T; Boykin, DW; Brun, R; Gonzalez, JL; Stephens, CE; Tanious, FA; Wenzler, T; Werbovetz, KA; Wilson, WD	1
Borne, RF; Khan, MO; Levi, MS; Tekwani, BL; Wilson, NH	1
Brun, R; de Koning, HP; Gould, M; Kaiser, M; Koomen, GJ; Rodenko, B; van der Burg, AM; Wanner, MJ	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Hall, JE; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Bharate, SB; Jacob, M; Khan, IA; Khan, SI; Singh, IP; Tekwani, BL	1
Brun, R; Dardonville, C; García, RN; Kaiser, M; Nguyen, B; Rodríguez, F; Rozas, I; Wilson, WD	1
Barrett, MP; Ebikeme, C; Müller, S; Patzewitz, EM; Reid, CM; Robins, DJ; Sutherland, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y	1
Hamann, MT; Kasanah, N; Shilabin, AG; Tekwani, BL	1
Bazzocchi, IL; Bourdy, G; Flores, N; Giménez, A; Gutiérrez, D; Jiménez, IA; Ruiz, G	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Tidwell, RR; Wenzler, T; Werbovetz, KA	2
Alley, MC; ElSohly, MA; Feng, S; Galal, AM; Gul, W; Hollingshead, MG; Kaur, G; Ross, SA; Slade, D	1
Ashfaq, MK; Jacob, MR; Joshi, VC; Khan, SI; Manly, SP; Muhammad, I; Samoylenko, V; Tekwani, BL; Walker, LA	1
Ahmed, SA; Elsohly, MA; Khan, IA; Radwan, MM; Ross, SA; Slade, D	1
Bakunov, SA; Bakunova, SM; Barzcz, T; Brun, R; Chen, H; Jones, SK; Kumar, EV; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M	1
Ahmed, SA; Elsohly, MA; Galal, AM; Gul, W; Jacob, MR; Khan, SI; Radwan, MM; Ross, SA; Slade, D; Tekwani, BL	1
Benicewicz, DB; Chen, PC; Gryder, B; Guerrant, W; Khan, SI; Oyelere, AK; Patil, V; Tekwani, BL	1
Bakunov, SA; Bakunova, SM; Brun, R; Ghebru, M; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Jain, M; Jain, R; Kaur, K; Reddy, RP	1
Guerrant, W; Gurard-Levin, ZA; Khan, SI; Mrksich, M; Mwakwari, SC; Oyelere, AK; Patil, V; Tekwani, BL	1
Cedillo-Rivera, R; Chan-Bacab, MJ; Estrada-Soto, S; Guerrero-Alvarez, J; León-Rivera, I; Mirón-López, G; Molina-Salinas, GM; Moo-Puc, R; Nava-Zuazo, C; Navarrete-Vazquez, G; Said-Fernández, S	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Baumann, K; Bischof, SK; Bringmann, G; Brun, R; Dreher, J; Gulder, T; Kaiser, M; Moll, H; Müller, S; Stich, A; Winter, C	1
Jacob, MR; Jain, M; Jain, R; Kaur, K; Khan, SI; Singh, PP; Singh, S; Tekwani, BL	2
Carvalho, L; Castanys, S; Gamarro, F; Manzano, JI; Pérez-Victoria, JM	1
Bodo, B; Kamoga, D; Kasenene, J; Lacroix, D; Prado, S	1
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y	1
Duke, SO; Ferreira, D; Jacob, M; Khan, SI; Kumarihamy, M; Nanayakkara, NP; Tekwani, BL	1
Azas, N; Casanova, M; Castera-Ducros, C; Dumètre, A; Hutter, S; Kraiem-M'rabet, M; Laget, M; Mbatchi, L; Paloque, L; Rathelot, P; Rault, S; Remusat, V; Vanelle, P; Verhaeghe, P	1
Cutler, HG; Cutler, SJ; Dugan, FM; Gao, J; Hill, RA; Jacob, MR; Khan, SI; León, F; Lupien, S; Radwan, MM; Tekwani, BL; Wang, X	1
Chauhan, PM; Gupta, S; Khan, S; Kidwai, S; Puri, SK; Shivahare, R; Srivastava, K; Tyagi, V	1
Kaiser, M; McKeever, C; Rozas, I	1
Buisson, D; Fromentin, Y; Gaboriaud-Kolar, N; Grellier, P; Lallemand, MC; Lenta, BN; Loiseau, PM; Michel, S; Mouray, E; Wansi, JD	1
Arafa, RK; Boykin, DW; Brun, R; Ismail, MA; Jones, SK; Pandharkar, T; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA; Zhu, X	1
Abada, Z; Akagah, B; Cojean, S; Ferrié, L; Figadère, B; Loiseau, PM; Lormier, AT; Pomel, S	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Boykin, DW; Brun, R; Jones, SK; Kumar, A; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Dubois, J; Grellier, P; Thévenin, M; Thoret, S	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Brun, R; Harel, D; Prinz, H; Schepmann, D; Schmidt, TJ; Wünsch, B	1
Bakunov, SA; Bakunova, SM; Brun, R; Patrick, DA; Tidwell, RR; Wenzler, T	1
Agnamey, P; Azas, N; Cohen, A; Daulouede, S; Del Favero, M; Farvacques, N; Guillon, J; Hutter, S; Le Pape, P; Mullié, C; Pagniez, F; Pinaud, N; Ronga, L; Savrimoutou, S; Sonnet, P; Soum, C; Vincendeau, P	1
Al-Salabi, MI; Ali, JA; de Koning, HP; El-Sabbagh, N; Ho, W; Ibrahim, HM; Koomen, GJ; Rodenko, B; Teka, IA; Wanner, MJ	1
Boykin, DW; Brun, R; Liu, ZY; Wenzler, T; Zhu, X	1
Avery, VM; Baell, JB; Bergström, CA; Charman, SA; Ferrins, L; Gazdik, M; Jones, AJ; Kaiser, M; Rahmani, R; Ryan, E; Sykes, ML; Varghese, S; White, KL	1
Azas, N; Bouhlel, A; Cohen, A; Curti, C; Hutter, S; Primas, N; Remusat, V; Tabélé, C; Terme, T; Vanelle, P	1
Chabot, GG; Deguin, B; Dumontet, V; Espindola, LS; Grellier, P; Grougnet, R; Mai, LH; Michel, S; Poulain, C; Quentin, L; Vo, HT	1
Bosc, D; Cojean, S; Dubois, J; Franco, CH; Freitas-Junior, LH; Grellier, P; Loiseau, PM; Moraes, CB; Mouray, E	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Carvalho, P; Cutler, SJ; Dale, OR; Elokely, KM; ElSohly, MA; Galal Osman, A; Gul, W; Husni, AS; Khan, S; Klein, ML; Radwan, M; Ross, SA; Slade, D; Yadav, VK	1
Berger, O; Bressolle, F; Denoyelle, S; Durand, T; Escale, R; Ortial, S; Vial, HJ; Vo-Hoang, Y; Wein, S	1
Hoppe, HC; Isaacs, M; Kaye, PT; Krause, RWM; Manyeruke, MH; Seldon, R; Tshiwawa, T; Warner, DF	1
Carvalho, C; Cordeiro da Silva, A; Duarte, D; Kijjoa, A; Long, S; Moreira, R; Nogueira, F; Oliveira, R; Palmeira, A; Pinto, MMM; Resende, DISP; Santarém, N; Silva, AMS; Sousa, E	1
Gill, F; Miller, LH; Neva, FA	1
Mattock, NM; Peters, W	1
Allen, MA; Bell, CA; Grogl, M; Hall, JE; Kyle, DE; Ohemeng, KA; Tidwell, RR	1
Bartlett, MS; Eichholtz, R; Smith, JW	1
Barrett-Connor, E	1
Burwell, EL; Dana, MM; Etkind, P; Fleishman, PR; Juranek, DD; Sato, K; Teutsch, SM	1
Catisti, R; Docampo, R; Rodrigues, CO; Vercesi, AE	1
Azas, N; Dumètre, A; Gellis, A; Hutter, S; Lanzada, G; Ollivier, E; Vanelle, P	1
Heukers, R; Houtman, MJ; Man, JC; Takanari, H; Tieland, RG; van Bergen En Henegouwen, PM; van der Heyden, MA; Varkevisser, R; Vos, MA; Waasdorp, M	1
Bohme, GA; Filoche-Rommé, B; Partiseti, M; Sanson, C; Schombert, B	1

Reviews

3 review(s) available for chloroquine and pentamidine

Article	Year
Quinolines and structurally related heterocycles as antimalarials. European journal of medicinal chemistry, 2010, Volume: 45, Issue:8 Topics: Animals; Antimalarials; Humans; Quinolines; Structure-Activity Relationship	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drugs for the treatment of parasitic infection. The Medical clinics of North America, 1982, Volume: 66, Issue:1 Topics: Antimony; Bithionol; Chloroquine; Diethylcarbamazine; Humans; Mebendazole; Melarsoprol; Metronidazole; Niclosamide; Niridazole; Oxamniquine; Parasitic Diseases; Pentamidine; Piperazines; Primaquine; Pyrantel Pamoate; Pyrimethamine; Suramin; Thiabendazole; Trichlorfon	1982

Other Studies

85 other study(ies) available for chloroquine and pentamidine

Article	Year
Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Animals; Antiprotozoal Agents; Chlorocebus aethiops; Diphosphonates; Leishmania donovani; Plasmodium falciparum; Structure-Activity Relationship; Toxoplasma; Trypanosoma brucei brucei; Trypanosoma cruzi; Vero Cells	2001
Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. Bioorganic & medicinal chemistry letters, 2001, Oct-08, Volume: 11, Issue:19 Topics: Animals; Antiprotozoal Agents; Leishmania; Parasitic Sensitivity Tests; Plasmodium; Quinacrine; Sulfonamides; Trypanosoma; Urea	2001
Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. Journal of natural products, 2002, Volume: 65, Issue:10 Topics: Animals; Antiprotozoal Agents; Drug Screening Assays, Antitumor; Galphimia; Leishmania donovani; Plasmodium falciparum; Spectrum Analysis; Triterpenes; Trypanosoma brucei brucei; Tumor Cells, Cultured	2002
Antimicrobial and antiparasitic (+)-trans-hexahydrodibenzopyrans and analogues from Machaerium multiflorum. Journal of natural products, 2003, Volume: 66, Issue:6 Topics: Animals; Anti-Infective Agents; Antimalarials; Antiparasitic Agents; Benzopyrans; Candida albicans; Fabaceae; Inhibitory Concentration 50; Leishmania donovani; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peru; Plant Bark; Plants, Medicinal; Plasmodium falciparum; Staphylococcus aureus; Stereoisomerism	2003
New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge. Journal of natural products, 2003, Volume: 66, Issue:6 Topics: Alkaloids; Animals; Anti-HIV Agents; Antiprotozoal Agents; Carbazoles; Carbolines; Crystallography, X-Ray; Indoles; Indonesia; Inhibitory Concentration 50; Leishmania donovani; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleosides; Porifera; Pyrroles; Stereoisomerism	2003
Antiparasitic alkaloids from Psychotria klugii. Journal of natural products, 2003, Volume: 66, Issue:7 Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leishmania donovani; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peru; Plants, Medicinal; Plasmodium falciparum; Psychotria; Quinazolines; Tumor Cells, Cultured	2003
Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria. Journal of medicinal chemistry, 2003, Sep-25, Volume: 46, Issue:20 Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemisinins; Clone Cells; Drug Design; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Leishmania donovani; Malaria, Falciparum; Models, Molecular; Molecular Conformation; Plasmodium falciparum; Sesquiterpenes; Static Electricity; Stereoisomerism; Structure-Activity Relationship	2003
Diamine derivatives with antiparasitic activities. Bioorganic & medicinal chemistry letters, 2004, Feb-09, Volume: 14, Issue:3 Topics: Animals; Antiparasitic Agents; Diamines; Drug Design; In Vitro Techniques; Leishmania donovani; Libraries; Plasmodium falciparum; Structure-Activity Relationship	2004
Parallel solution-phase synthesis of conformationally restricted congeners of pentamidine and evaluation of their antiplasmodial activities. Journal of medicinal chemistry, 2004, May-06, Volume: 47, Issue:10 Topics: Animals; Antimalarials; Cell Line, Tumor; Cell-Free System; Chloroquine; Drug Resistance; Hemin; Humans; Molecular Conformation; Plasmodium falciparum; Structure-Activity Relationship	2004
A new antimalarial quassinoid from Simaba orinocensis. Journal of natural products, 2004, Volume: 67, Issue:5 Topics: Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Molecular Structure; Peru; Plants, Medicinal; Plasmodium falciparum; Quassins; Simaroubaceae; Tumor Cells, Cultured	2004
Three new manzamine alkaloids from a common Indonesian sponge and their activity against infectious and tropical parasitic diseases. Journal of natural products, 2004, Volume: 67, Issue:8 Topics: Alkaloids; Animals; Anti-HIV Agents; Anti-Infective Agents; Antimalarials; Antiprotozoal Agents; Carbolines; Indonesia; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Porifera	2004
Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database. Journal of medicinal chemistry, 2004, Dec-16, Volume: 47, Issue:26 Topics: Animals; Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Databases, Factual; Leishmania donovani; Models, Molecular; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Trypanocidal Agents	2004
Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate. Journal of medicinal chemistry, 2005, Nov-17, Volume: 48, Issue:23 Topics: Animals; Antimalarials; Antiprotozoal Agents; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Drug Storage; Glutathione; Glutathione Reductase; Humans; Ketones; Leishmania donovani; Magnetic Resonance Spectroscopy; Mannich Bases; NADH, NADPH Oxidoreductases; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxin-Disulfide Reductase; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2005
Alkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents. Bioorganic & medicinal chemistry letters, 2006, Mar-01, Volume: 16, Issue:5 Topics: Alkylation; Animals; Carboxylic Acids; Leishmania donovani; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Thiadiazines; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2006
Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases. Journal of natural products, 2006, Volume: 69, Issue:7 Topics: Alzheimer Disease; Animals; Female; Glycogen Synthase Kinase 3; HIV-1; Humans; Indole Alkaloids; Indonesia; Inhibitory Concentration 50; Leishmania donovani; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oryzias; Plasmodium falciparum; Porifera; Structure-Activity Relationship	2006
Evaluation of azasterols as anti-parasitics. Journal of medicinal chemistry, 2006, Oct-05, Volume: 49, Issue:20 Topics: Animals; Antimalarials; Azasteroids; Leishmania donovani; Methyltransferases; Plasmodium falciparum; Stereoisomerism; Sterols; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2006
Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols. Bioorganic & medicinal chemistry, 2007, Jan-01, Volume: 15, Issue:1 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antiprotozoal Agents; Candida albicans; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Cryptococcus neoformans; Epithelial Cells; Leishmania donovani; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Phloroglucinol; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vero Cells	2007
Synthesis, antimalarial, antileishmanial, antimicrobial, cytotoxicity, and methemoglobin (MetHB) formation activities of new 8-quinolinamines. Bioorganic & medicinal chemistry, 2007, Jan-15, Volume: 15, Issue:2 Topics: Aminoquinolines; Animals; Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antiparasitic Agents; Bacteria; Chlorocebus aethiops; Erythrocytes; Fungi; Humans; Indicators and Reagents; L-Lactate Dehydrogenase; Leishmania donovani; Magnetic Resonance Spectroscopy; Methemoglobin; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Vero Cells	2007
Synthesis and evaluation of isosteres of N-methyl indolo[3,2-b]-quinoline (cryptolepine) as new antiinfective agents. Bioorganic & medicinal chemistry, 2007, Jan-15, Volume: 15, Issue:2 Topics: Alkaloids; Animals; Anti-Infective Agents; Antimalarials; Antiparasitic Agents; Bacteria; Cell Line; Cell Survival; Chemical Phenomena; Chemistry, Physical; Chlorocebus aethiops; Fungi; Humans; Indicators and Reagents; Indole Alkaloids; Indoles; Isomerism; Leishmania donovani; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship; Vero Cells	2007
Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes. European journal of medicinal chemistry, 2007, Volume: 42, Issue:4 Topics: Animals; Antiparasitic Agents; Disease Models, Animal; Guanidines; Leishmania; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium; Thiophenes; Trypanosoma	2007
Synthesis of isoquinuclidine analogs of chloroquine: antimalarial and antileishmanial activity. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Animals; Antimalarials; Antiprotozoal Agents; Chloroquine; Leishmania; Plasmodium falciparum; Quinuclidines	2007
2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Adenosine; Animals; Antimalarials; Dose-Response Relationship, Drug; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2007
Synthesis and in vitro antiprotozoal activity of bisbenzofuran cations. Journal of medicinal chemistry, 2007, Nov-15, Volume: 50, Issue:23 Topics: Animals; Antimalarials; Benzofurans; Cations; Leishmania donovani; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2007
S-Euglobals: biomimetic synthesis, antileishmanial, antimalarial, and antimicrobial activities. Bioorganic & medicinal chemistry, 2008, Feb-01, Volume: 16, Issue:3 Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Biomimetic Materials; Leishmania donovani; Magnetic Resonance Spectroscopy; Molecular Structure; Mycobacterium avium Complex; Phloroglucinol; Plasmodium falciparum; Staphylococcus aureus; Structure-Activity Relationship; Terpenes	2008
New bis(2-aminoimidazoline) and bisguanidine DNA minor groove binders with potent in vivo antitrypanosomal and antiplasmodial activity. Journal of medicinal chemistry, 2008, Feb-28, Volume: 51, Issue:4 Topics: Animals; Antimalarials; Cell Line; DNA; Female; Guanidines; Hemeproteins; Hemin; Imidazolines; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship; Transition Temperature; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2008
Synthesis and anti-protozoal activity of C2-substituted polyazamacrocycles. Bioorganic & medicinal chemistry letters, 2008, Apr-01, Volume: 18, Issue:7 Topics: Animals; Antiprotozoal Agents; Aza Compounds; Humans; Kidney; Macrocyclic Compounds; Malaria; Models, Chemical; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanosoma	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26 Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase	2008
Kinetic studies and bioactivity of potential manzamine prodrugs. Journal of natural products, 2008, Volume: 71, Issue:7 Topics: Administration, Oral; Animals; Antimalarials; Candida albicans; Carbolines; Chlorocebus aethiops; Cryptococcus neoformans; Disease Models, Animal; Inhibitory Concentration 50; Leishmania donovani; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Structure; Plasmodium falciparum; Prodrugs; Vero Cells	2008
Benzoic acid derivatives from Piper species and their antiparasitic activity. Journal of natural products, 2008, Volume: 71, Issue:9 Topics: Animals; Antimalarials; Antiparasitic Agents; Antiprotozoal Agents; Benzoates; Bolivia; Leishmania; Molecular Structure; Parasitic Sensitivity Tests; Piper; Plant Leaves; Plants, Medicinal; Plasmodium falciparum; Trypanosoma cruzi	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Animals; Antiprotozoal Agents; Benzofurans; Cations; Disease Models, Animal; Leishmania; Mice; Molecular Structure; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis	2008
Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Antimalarials; Antineoplastic Agents; Antiprotozoal Agents; Artemisinins; Cell Line, Tumor; Dimerization; Drug Screening Assays, Antitumor; Humans; Leishmania; Mice; Structure-Activity Relationship; Xenograft Model Antitumor Assays	2009
Indolizidine, antiinfective and antiparasitic compounds from Prosopis glandulosa var. glandulosa. Journal of natural products, 2009, Volume: 72, Issue:1 Topics: Animals; Anti-Infective Agents; Antiparasitic Agents; Aspergillus fumigatus; Brain; Candida albicans; Chloroquine; Cryptococcus neoformans; Disease Models, Animal; Drug Screening Assays, Antitumor; Humans; Indolizidines; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Molecular Structure; Nevada; Plants, Medicinal; Plasmodium berghei; Prosopis	2009
Biologically active cannabinoids from high-potency Cannabis sativa. Journal of natural products, 2009, May-22, Volume: 72, Issue:5 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Aspergillus fumigatus; Candida; Cannabinoids; Cannabis; Chlorocebus aethiops; Escherichia coli; Gas Chromatography-Mass Spectrometry; Leishmania donovani; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Plasmodium falciparum; Pseudomonas aeruginosa	2009
Synthesis and antiprotozoal activities of dicationic bis(phenoxymethyl)benzenes, bis(phenoxymethyl)naphthalenes, and bis(benzyloxy)naphthalenes. European journal of medicinal chemistry, 2009, Volume: 44, Issue:9 Topics: Animals; Antiprotozoal Agents; Benzene; Cell Survival; Leishmania donovani; Mice; Myoblasts; Naphthalenes; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2009
Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Animals; Antiprotozoal Agents; Female; Leishmania donovani; Mice; Pentamidine; Plasmodium falciparum; Pyridines; Rats; Structure-Activity Relationship	2009
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences. Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18 Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum	2009
Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers. Bioorganic & medicinal chemistry, 2009, Dec-01, Volume: 17, Issue:23 Topics: Acetals; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Artemisinins; Cell Line, Tumor; Cryptococcus neoformans; Dimerization; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization	2009
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group. Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1 Topics: Antimalarials; Antiprotozoal Agents; Histone Deacetylase Inhibitors; Histone Deacetylases; Leishmania donovani; Leishmaniasis; Malaria; Plasmodium falciparum; Structure-Activity Relationship; Triazoles	2010
Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles. Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1 Topics: Amidines; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Disease Models, Animal; Female; Leishmania donovani; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Stereoisomerism; Structure-Activity Relationship; Triazoles; Trypanosoma brucei rhodesiense	2010
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids. Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5 Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton. Journal of medicinal chemistry, 2010, Aug-26, Volume: 53, Issue:16 Topics: Antimalarials; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Isoenzymes; Ketolides; Leishmania donovani; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents	2010
Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas. Bioorganic & medicinal chemistry, 2010, Sep-01, Volume: 18, Issue:17 Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Drug Design; Giardia lamblia; Humans; Leishmania mexicana; Mycobacterium tuberculosis; Quinolines; Structure-Activity Relationship; Urea	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Alkaloids; Animals; Antimalarials; Isoquinolines; Magnetic Resonance Spectroscopy; Models, Molecular; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared	2010
Synthesis, antiprotozoal, antimicrobial, β-hematin inhibition, cytotoxicity and methemoglobin (MetHb) formation activities of bis(8-aminoquinolines). Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1 Topics: Aminoquinolines; Animals; Anti-Infective Agents; Antiprotozoal Agents; Hemeproteins; Humans; Methemoglobin	2011
Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania major. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:3 Topics: Adenosine Triphosphate; Aminoquinolines; Antiprotozoal Agents; Drug Resistance; Glycolysis; Leishmania major; Pyruvate Kinase	2011
Structure and in vitro antiparasitic activity of constituents of Citropsis articulata root bark. Journal of natural products, 2011, Oct-28, Volume: 74, Issue:10 Topics: Alkaloids; Animals; Antimalarials; Chlorocebus aethiops; Coumarins; Glycosides; Inhibitory Concentration 50; Leishmania donovani; Parasitic Sensitivity Tests; Plant Roots; Plasmodium falciparum; Rutaceae; Uganda; Vero Cells	2011
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061 Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites	2011
Amino acid, dipeptide and pseudodipeptide conjugates of ring-substituted 8-aminoquinolines: synthesis and evaluation of anti-infective, β-haematin inhibition and cytotoxic activities. European journal of medicinal chemistry, 2012, Volume: 52 Topics: Amino Acids; Aminoquinolines; Animals; Anti-Infective Agents; Chemistry Techniques, Synthetic; Chlorocebus aethiops; Dipeptides; Fungi; Hemeproteins; Leishmania donovani; Mice; Peptidomimetics; Plasmodium falciparum; Vero Cells	2012
Antiprotozoal and antimicrobial compounds from the plant pathogen Septoria pistaciarum. Journal of natural products, 2012, May-25, Volume: 75, Issue:5 Topics: Alkaloids; Animals; Anti-Infective Agents; Antimalarials; Antiprotozoal Agents; Ascomycota; Aspergillus fumigatus; Candida albicans; Candida glabrata; Chlorocebus aethiops; Chloroquine; Cryptococcus neoformans; Escherichia coli; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium avium Complex; Plasmodium falciparum; Pseudomonas aeruginosa; Staphylococcus aureus; Vero Cells	2012
Discovery of a new antileishmanial hit in 8-nitroquinoline series. European journal of medicinal chemistry, 2012, Volume: 54 Topics: Animals; Antiprotozoal Agents; Drug Discovery; Hep G2 Cells; Humans; Leishmania donovani; Life Cycle Stages; Mice; Nitroquinolines	2012
Antimicrobial and antiprotozoal activities of secondary metabolites from the fungus Eurotium repens. Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2012, Volume: 21, Issue:10 Topics:	2012
A natural product inspired hybrid approach towards the synthesis of novel pentamidine based scaffolds as potential anti-parasitic agents. Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1 Topics: Antimalarials; Antiprotozoal Agents; Biological Products; Chalcone; Pentamidine; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship	2013
Aminoalkyl derivatives of guanidine diaromatic minor groove binders with antiprotozoal activity. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Animals; Antiprotozoal Agents; Guanidine; Nucleic Acid Denaturation; Plasmodium falciparum; Trypanosoma brucei rhodesiense	2013
Synthesis of novel guttiferone A derivatives: in-vitro evaluation toward Plasmodium falciparum, Trypanosoma brucei and Leishmania donovani. European journal of medicinal chemistry, 2013, Volume: 65 Topics: Antiprotozoal Agents; Benzophenones; Clusiaceae; Dose-Response Relationship, Drug; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Seeds; Structure-Activity Relationship; Trypanosoma brucei brucei	2013
Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives. Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13 Topics: Animals; Antiprotozoal Agents; Benzene; Chagas Disease; Female; Leishmania donovani; Mice; Mice, Inbred Strains; Models, Chemical; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Terphenyl Compounds; Trypanosoma cruzi	2013
Synthesis and antiprotozoal activity of original porphyrin precursors and derivatives. European journal of medicinal chemistry, 2013, Volume: 67 Topics: Antiprotozoal Agents; Dose-Response Relationship, Drug; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium; Porphyrins; Structure-Activity Relationship; Trypanosoma brucei brucei	2013
Synthesis and antiprotozoal activities of benzyl phenyl ether diamidine derivatives. European journal of medicinal chemistry, 2013, Volume: 67 Topics: Animals; Antiprotozoal Agents; Dose-Response Relationship, Drug; Leishmania donovani; Mice; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Pentamidine; Phenyl Ethers; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis	2013
Synthesis of polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth. Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17 Topics: Acylation; Antiprotozoal Agents; Benzofurans; Cyclization; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei brucei	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives. Journal of medicinal chemistry, 2013, Sep-26, Volume: 56, Issue:18 Topics: Antiprotozoal Agents; Biological Products; Chemistry Techniques, Synthetic; Chromans; Inhibitory Concentration 50; Structure-Activity Relationship	2013
Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Animals; Antiprotozoal Agents; Isoxazoles; Mice; Molecular Structure; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship; Trypanosomiasis, African	2014
Design, synthesis and biological evaluation of novel 4-alkapolyenylpyrrolo[1,2-a]quinoxalines as antileishmanial agents--part III. European journal of medicinal chemistry, 2014, Jun-23, Volume: 81 Topics: Animals; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Female; Hep G2 Cells; Humans; Leishmania; Macrophages; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinoxalines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2014
Synthesis of marine-derived 3-alkylpyridinium alkaloids with potent antiprotozoal activity. ACS medicinal chemistry letters, 2011, Dec-08, Volume: 2, Issue:12 Topics:	2011
Synthesis and antiparasitic activity of new bis-arylimidamides: DB766 analogs modified in the terminal groups. European journal of medicinal chemistry, 2014, Aug-18, Volume: 83 Topics: Amides; Animals; Antiparasitic Agents; Cell Line; Chemistry Techniques, Synthetic; Leishmania; Plasmodium falciparum; Rats; Trypanosoma	2014
Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei. Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15 Topics: Animals; Benzamides; Cell Line; HEK293 Cells; Humans; Microsomes, Liver; Myoblasts; Pyridines; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2014
New series of monoamidoxime derivatives displaying versatile antiparasitic activity. European journal of medicinal chemistry, 2014, Nov-24, Volume: 87 Topics: Antiparasitic Agents; Carbon-13 Magnetic Resonance Spectroscopy; Inhibitory Concentration 50; Oximes; Spectrometry, Mass, Electrospray Ionization	2014
Antivascular and anti-parasite activities of natural and hemisynthetic flavonoids from New Caledonian Gardenia species (Rubiaceae). European journal of medicinal chemistry, 2015, Mar-26, Volume: 93 Topics: Angiogenesis Inhibitors; Animals; Antiparasitic Agents; Cell Line, Tumor; Cell Survival; Drug Design; Flavonoids; Flowers; Gardenia; Humans; Leishmania; Molecular Structure; New Caledonia; Plant Extracts; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei gambiense	2015
Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors. European journal of medicinal chemistry, 2016, Feb-15, Volume: 109 Topics: Alkyl and Aryl Transferases; Animals; Antiparasitic Agents; Cell Line; Enzyme Inhibitors; Humans; Imidazoles; Leishmania donovani; Leishmaniasis, Visceral; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis	2016
Bioactive products from singlet oxygen photooxygenation of cannabinoids. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antiprotozoal Agents; Bacteria; Cannabinoids; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fungi; Humans; Leishmania major; Microbial Sensitivity Tests; Parasitic Sensitivity Tests; Photochemical Processes; Plasmodium falciparum; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Singlet Oxygen	2018
Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials. Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16 Topics: Antimalarials; Humans; Oximes; Plasmodium falciparum; Prodrugs	2019
Synthesis and biological evaluation of bis-N Bioorganic & medicinal chemistry letters, 2020, 03-01, Volume: 30, Issue:5 Topics: Antifungal Agents; Antitubercular Agents; Catalytic Domain; Coumarins; HeLa Cells; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Hydrazines; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Protein Binding; Trypanocidal Agents; Trypanosoma brucei brucei	2020
Indole-Containing Pyrazino[2,1- ACS medicinal chemistry letters, 2022, Feb-10, Volume: 13, Issue:2 Topics:	2022
Failure of chloroquine in human babesiosis (Babesia microti): case report and chemotherapeutic trials in hamsters. Annals of internal medicine, 1978, Volume: 88, Issue:2 Topics: Animals; Babesiosis; Benzamidines; Chloroquine; Cricetinae; Drug Resistance; Humans; Male; Metronidazole; Middle Aged; Minocycline; Pentamidine; Pyrimethamine; Recurrence; Sulfadiazine; Tetracycline; Time Factors	1978
The experimental chemotherapy of leishmaniasis. II. The activity in tissue culture of some antiparasitic and antimicrobial compounds in clinical use. Annals of tropical medicine and parasitology, 1975, Volume: 69, Issue:3 Topics: Aminoquinolines; Animals; Anti-Bacterial Agents; Antimalarials; Antimony; Antiprotozoal Agents; Ascitic Fluid; Cell Line; Chloroquine; Cricetinae; Culture Techniques; Dogs; Drug Evaluation, Preclinical; Folic Acid Antagonists; Leishmania; Niridazole; Pentamidine; Primaquine; Quinacrine; Quinine; Sarcoma; Sulfonamides; Sulfones; Suramin	1975
Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:7 Topics: Animals; Chloroquine; Drug Resistance, Microbial; Leishmania mexicana; Mefloquine; Pentamidine; Plasmodium falciparum; Structure-Activity Relationship	1990
Antimicrobial susceptibility of Pneumocystis carinii in culture. Diagnostic microbiology and infectious disease, 1985, Volume: 3, Issue:5 Topics: Amphotericin B; Animals; Anti-Infective Agents; Cell Line; Chloroquine; Culture Media; Drug Combinations; Humans; Metronidazole; Miconazole; Pentamidine; Pneumocystis; Rats; Rats, Inbred Strains; Sulfamethoxazole; Time Factors; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1985
Babesiosis in post-splenectomy hosts. The American journal of tropical medicine and hygiene, 1980, Volume: 29, Issue:5 Topics: Animals; Babesiosis; Chloroquine; Female; Humans; Male; Massachusetts; Middle Aged; New York; Pentamidine; Postoperative Complications; Splenectomy	1980
Presence of a Na(+)/H(+) exchanger in acidocalcisomes of Leishmania donovani and their alkalization by anti-leishmanial drugs. FEBS letters, 2000, May-12, Volume: 473, Issue:2 Topics: Acridine Orange; Adenosine Triphosphate; Aminoquinolines; Ammonium Chloride; Animals; Antiprotozoal Agents; Butylated Hydroxytoluene; Chloroquine; Hydrogen-Ion Concentration; Leishmania donovani; Pentamidine; Sodium Chloride; Sodium-Hydrogen Exchangers; Vacuoles	2000
Preparation and antiprotozoal evaluation of promising β-carboline alkaloids. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:5 Topics: Alkaloids; Amphotericin B; Antiprotozoal Agents; Carbolines; Chloroquine; Doxycycline; Drug Resistance, Multiple; Humans; Inhibitory Concentration 50; Leishmania donovani; Pentamidine; Plasmodium falciparum; Structure-Activity Relationship	2012
Inhibiting the clathrin-mediated endocytosis pathway rescues K(IR)2.1 downregulation by pentamidine. Pflugers Archiv : European journal of physiology, 2013, Volume: 465, Issue:2 Topics: Action Potentials; Antiprotozoal Agents; Cell Membrane; Chloroquine; Chlorpromazine; Clathrin-Coated Vesicles; Down-Regulation; Endocytosis; HEK293 Cells; Humans; Hydrazones; Macrolides; Pentamidine; Potassium Channels, Inwardly Rectifying; Protein Transport; Proteolysis	2013
Electrophysiological and Pharmacological Characterization of Human Inwardly Rectifying K Assay and drug development technologies, 2019, Volume: 17, Issue:3 Topics: Animals; Automation; Chloroquine; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Humans; Imidazoles; Molecular Structure; Pentamidine; Phenanthrolines; Potassium Channels, Inwardly Rectifying	2019