Compounds > chloroquine

chloroquine and panobinostat

chloroquine has been researched along with panobinostat in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Andrews, KT; Antonova-Koch, Y; Avery, VM; Diedrich, D; Duffy, S; Fisher, G; Gebru, T; Hansen, FK; Held, J; Hesping, E; Kurz, T; Meister, S; Schöler, A; Stenzel, K; Winzeler, EA1
Chan, SSL; Chou, CJ; Dolloff, N; Halene, S; Himes, RA; Inks, ES; Jiang, Y; Li, X; Luo, X; Peterson, YK; Xu, T; Yin, G1
Atadja, P; Balusu, R; Bhalla, KN; Chauhan, L; Fiskus, W; Ha, K; Hembruff, SL; Mudunuru, U; Rao, R; Smith, JE; Venkannagari, S1
Goodson, H; Helquist, P; Huegel, KL; Hulett, TW; Vaughan, KT; Wehrmann, ZT; Wiest, O1
González-Sarmiento, R; Herrero, AB; Ovejero-Sánchez, M1
González-Sarmiento, R; Herrero, AB; Ovejero-Sánchez, M; Pérez-Losada, J; Rubio-Heras, J; San-Segundo, L; Vicente de la Peña, MDC1

Other Studies

6 other study(ies) available for chloroquine and panobinostat

ArticleYear
One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Acetylation; Antimalarials; Hep G2 Cells; Histone Deacetylase Inhibitors; Histones; Humans; Malaria, Falciparum; Peptoids; Plasmodium falciparum; Protozoan Proteins

2018
Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity.
    Journal of medicinal chemistry, 2020, 05-28, Volume: 63, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Design; fms-Like Tyrosine Kinase 3; Histone Deacetylase Inhibitors; Leukemia, Myeloid, Acute; Male; Mice; Panobinostat; Tumor Suppressor Protein p53

2020
Combination of pan-histone deacetylase inhibitor and autophagy inhibitor exerts superior efficacy against triple-negative human breast cancer cells.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Chloroquine; Drug Synergism; Female; Histone Deacetylase Inhibitors; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Indoles; Mice; Mice, Inbred NOD; Mice, SCID; Microscopy, Confocal; Panobinostat; Xenograft Model Antitumor Assays

2012
Quantitative comparison of the efficacy of various compounds in lowering intracellular cholesterol levels in Niemann-Pick type C fibroblasts.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Azacitidine; beta-Cyclodextrins; Cells, Cultured; Child; Child, Preschool; Chloroquine; Chlorpromazine; Cholesterol; Decitabine; Dose-Response Relationship, Drug; Drug Synergism; Female; Fibroblasts; Humans; Hydroxamic Acids; Indoles; Intracellular Space; Male; Microscopy, Fluorescence; Mutation; Niemann-Pick Disease, Type C; Panobinostat; Sirolimus; Vorinostat

2012
Synergistic effect of Chloroquine and Panobinostat in ovarian cancer through induction of DNA damage and inhibition of DNA repair.
    Neoplasia (New York, N.Y.), 2021, Volume: 23, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Chloroquine; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Drug Synergism; Female; Humans; Ovarian Neoplasms; Panobinostat; Reactive Oxygen Species; Recombinational DNA Repair

2021
Chloroquine-Induced DNA Damage Synergizes with Nonhomologous End Joining Inhibition to Cause Ovarian Cancer Cell Cytotoxicity.
    International journal of molecular sciences, 2022, Jul-07, Volume: 23, Issue:14

    Topics: Carcinoma, Ovarian Epithelial; Chloroquine; DNA Breaks, Double-Stranded; DNA Damage; DNA End-Joining Repair; DNA Repair; Female; Humans; Ovarian Neoplasms; Panobinostat; Reactive Oxygen Species

2022