chloroquine and paclitaxel

chloroquine has been researched along with paclitaxel in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.44)	18.7374
1990's	1 (2.44)	18.2507
2000's	11 (26.83)	29.6817
2010's	21 (51.22)	24.3611
2020's	7 (17.07)	2.80

Authors

Authors	Studies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Alley, MC; ElSohly, MA; Feng, S; Galal, AM; Gul, W; Hollingshead, MG; Kaur, G; Ross, SA; Slade, D	1
Balachandran, R; Bell, SL; Brodsky, JL; Chen, XS; Chiang, AN; Chovatiya, RJ; Day, BW; Fidock, DA; Huryn, DM; Klein, MG; Mead, BP; Schneider, C; Valderramos, JC; Wipf, P	1
Alumasa, JN; Brodie, PJ; Callmander, MW; Cao, S; Hou, Y; Kingston, DG; Rakotobe, EA; Rasamison, VE; Ratovoson, F; Ratsimbason, M; Roepe, PD	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Ahmed, SA; Elsohly, MA; Galal, AM; Gul, W; Jacob, MR; Khan, SI; Radwan, MM; Ross, SA; Slade, D; Tekwani, BL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Alumasa, JN; Birkinshaw, C; Brodie, PJ; Gorka, AP; Harinantenaina, L; Kingston, DG; Pan, E; Randrianaivo, R; Roepe, PD; Slebodnick, C	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Avery, VM; Sykes, ML	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Lee, H; Srivastava, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bi, C; Deng, H; Fan, T; Shao, R; Song, D; Wang, Y; Yang, P; Ye, C; Zhang, N	1
Awale, S; Bringmann, G; Bruhn, T; Brun, R; Feineis, D; Kaiser, M; Li, J; Mudogo, V; Seupel, R	1
Horrocks, P; Johnson-Ajinwo, OR; Li, WW; Mbye, H; Richardson, A; Ullah, I	1
Dymock, BW; Kitagawa, M; Lee, KH; Lee, SH; Liao, PJ; See, CS; Wong, J	1
Alcover, CF; Beniddir, MA; Bernadat, G; Fox Ramos, AE; Gallard, JF; Grellier, P; Kabran, FA; Le Pogam, P; Leblanc, K; Mouray, E; Poupon, E	1
Beniddir, MA; Champy, P; Grellier, P; Kumulungui, B; Le Pogam, P; Mouray, E; Ndong Mba, T; Otogo N'Nang, E; Sima Obiang, C	1
Charlwood, PA; Chindemi, PA; Regoeczi, E	1
Balkenende, AY; Slaper-Cortenbach, IC; van den Berg, H; van der Schoot, CE; Van Leeuwen, EF; Vervoordeldonk, SF; von dem Borne, AE	1
Bahr, BA; Bendiske, J; Butler, D; Karanian, DA; Michaelis, ML	1
Jenks, S	1
Chen, X; Li, Y; Xu, L; Xu, Z; Yin, Q; Yu, H; Zhang, Z	1
Li, X; Liu, S	1
Gao, M; Qiu, L; Xu, Y	1
Choi, AR; Kim, HS; Kim, JH; Woo, YH; Yoon, S	1
Bandopadhyay, S; Chakrabarti, G; Choudhury, D; Das, A; Dasgupta, M; Datta, S; Mukherjee, DD	1
Alves, M; Chollet, C; Fougeray, T; Franchet, C; Garmy-Susini, B; Gomez-Brouchet, A; Guillermet-Guibert, J; Lacazette, E; Martinez, LO; Najib, S; Prats, AC; Tatin, F; Therville, N; Vaysse, C; Zamora, A	1
Cai, K; Li, K; Lin, C; Lu, L; Luo, Z; Shen, X; Tao, B	1
Li, Z; Lin, F; Luo, SQ; Qiu, JL; Xiang, M; Zhu, YT	1
Antonyak, MA; Bryant, KL; Cerione, RA; Chang, WH; Der, CJ; Erickson, JW; Hsu, CH; Kim, HJ; Nguyen, TT; Ying, H	1
Bruzzese, F; Budillon, A; Caputo, R; Ciardiello, C; Cocco, S; Costantini, S; De Laurentiis, M; Leone, A; Lombardi, R; Piezzo, M; Roca, MS; Sisalli, MJ	1
Duarte, D; Nunes, M; Ricardo, S; Vale, N	1
Cai, J; Cai, Y; Du, Q; Guo, X; Ma, Q; Xu, L; Yuan, Z; Zhong, X	1

Reviews

2 review(s) available for chloroquine and paclitaxel

Article	Year
Approaches to protozoan drug discovery: phenotypic screening. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2013
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

39 other study(ies) available for chloroquine and paclitaxel

Article	Year
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Antimalarials; Antineoplastic Agents; Antiprotozoal Agents; Artemisinins; Cell Line, Tumor; Dimerization; Drug Screening Assays, Antitumor; Humans; Leishmania; Mice; Structure-Activity Relationship; Xenograft Model Antitumor Assays	2009
Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum. Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4 Topics: Adenosine Triphosphatases; Amides; Animals; Antimalarials; Erythrocytes; HSP70 Heat-Shock Proteins; Humans; Malaria, Falciparum; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimidinones	2009
Antiproliferative and antimalarial anthraquinones of Scutia myrtina from the Madagascar forest. Bioorganic & medicinal chemistry, 2009, Apr-01, Volume: 17, Issue:7 Topics: Animals; Anthraquinones; Antimalarials; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Madagascar; Plant Bark; Plant Extracts; Plasmodium falciparum; Rhamnaceae	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers. Bioorganic & medicinal chemistry, 2009, Dec-01, Volume: 17, Issue:23 Topics: Acetals; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Artemisinins; Cell Line, Tumor; Cryptococcus neoformans; Dimerization; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
Antiplasmodial and antiproliferative pseudoguaianolides of Athroisma proteiforme from the Madagascar Dry Forest. Journal of natural products, 2011, Oct-28, Volume: 74, Issue:10 Topics: Antimalarials; Antineoplastic Agents, Phytogenic; Asteraceae; Drug Screening Assays, Antitumor; Female; Flavonoids; Humans; Inhibitory Concentration 50; Lactones; Madagascar; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Trees	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Synthesis and bio-evaluation of novel quinolino-stilbene derivatives as potential anticancer agents. Bioorganic & medicinal chemistry, 2015, Dec-15, Volume: 23, Issue:24 Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Neoplasms; Quinolines; Stilbenes; Tubulin; Tubulin Modulators	2015
Synthesis, Biological Evaluation, and Autophagy Mechanism of 12 ACS medicinal chemistry letters, 2017, Feb-09, Volume: 8, Issue:2 Topics:	2017
Jozilebomines A and B, Naphthylisoquinoline Dimers from the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line. Journal of natural products, 2017, 10-27, Volume: 80, Issue:10 Topics: Algorithms; Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Congo; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Isoquinolines; Leishmania donovani; Magnoliopsida; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Pancreatic Neoplasms; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Tumor Cells, Cultured	2017
The synthesis and evaluation of thymoquinone analogues as anti-ovarian cancer and antimalarial agents. Bioorganic & medicinal chemistry letters, 2018, 04-15, Volume: 28, Issue:7 Topics: Antimalarials; Antineoplastic Agents; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2018
Discovery of the cancer cell selective dual acting anti-cancer agent (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile (A131). European journal of medicinal chemistry, 2018, Aug-05, Volume: 156 Topics: Acrylonitrile; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitosis; Neoplasms; Rats	2018
Molecular Networking Reveals Serpentinine-Related Bisindole Alkaloids from Journal of natural products, 2020, 04-24, Volume: 83, Issue:4 Topics: Antiparasitic Agents; Apocynaceae; Indole Alkaloids; Molecular Structure; Monoterpenes; Plasmodium falciparum; Secologanin Tryptamine Alkaloids	2020
Targeted Isolation of Hemitheion from Journal of natural products, 2021, 04-23, Volume: 84, Issue:4 Topics: Antimalarials; Cell Line; Gabon; Humans; Indole Alkaloids; Loganiaceae; Molecular Structure; Oxindoles; Phytochemicals; Plant Stems; Plasmodium falciparum	2021
The effects of cytotropic compounds on the resialylation of human asialotransferrin type 3 in the rat. Experimental cell research, 1985, Volume: 157, Issue:2 Topics: Alkaloids; Animals; Asialoglycoproteins; Chloroquine; Colchicine; Female; Humans; Leupeptins; Liver; Lysine; Male; Microtubules; Paclitaxel; Protein Biosynthesis; Rats; Starvation; Transferrin; Vinblastine	1985
Degradation of radioiodinated B cell monoclonal antibodies: inhibition via a FCgamma-receptor-II-mediated mechanism and by drugs. Cancer immunology, immunotherapy : CII, 1996, Volume: 42, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; B-Lymphocytes; Biological Transport; Burkitt Lymphoma; Calcium Channel Blockers; Cell Adhesion Molecules; Chloroquine; Colchicine; Etoposide; Humans; Immunoglobulin Isotypes; Immunotoxins; Iodine Radioisotopes; Lectins; Leukemia, B-Cell; Mice; Monensin; Paclitaxel; Radioimmunotherapy; Receptors, IgG; Sialic Acid Binding Ig-like Lectin 2; Verapamil; Vinblastine; Vincristine	1996
Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers. European journal of pharmacology, 2007, May-07, Volume: 562, Issue:1-2 Topics: Acetylation; Actins; Animals; Chloroquine; Dose-Response Relationship, Drug; Hippocampus; Immunoblotting; Organ Culture Techniques; Paclitaxel; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synaptophysin; Time Factors; Tubulin Modulators	2007
AACR highlights: promise for treating pancreatic cancer. Journal of the National Cancer Institute, 2011, May-18, Volume: 103, Issue:10 Topics: Albumin-Bound Paclitaxel; Albumins; Anilides; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Chloroquine; Clinical Trials as Topic; Delayed Diagnosis; Deoxycytidine; Disease Progression; Gemcitabine; Genes, ras; Humans; Mice; Molecular Targeted Therapy; Mutation; Off-Label Use; Paclitaxel; Pancreatic Neoplasms; Pyridines; Signal Transduction; Transcription Factors; United States	2011
Reversal of lung cancer multidrug resistance by pH-responsive micelleplexes mediating co-delivery of siRNA and paclitaxel. Macromolecular bioscience, 2014, Volume: 14, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Chloroquine; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Humans; Hydrogen-Ion Concentration; Luciferases; Lung Neoplasms; Macrolides; Micelles; Nanoparticles; Paclitaxel; Polymethacrylic Acids; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Transfection	2014
Autophagy inhibition enhances sensitivity of endometrial carcinoma cells to paclitaxel. International journal of oncology, 2015, Volume: 46, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line, Tumor; Chloroquine; Drug Synergism; Endometrial Neoplasms; Female; Humans; Membrane Proteins; Microtubule-Associated Proteins; Paclitaxel; RNA-Binding Proteins; Tubulin Modulators	2015
Enhanced combination therapy effect on paclitaxel-resistant carcinoma by chloroquine co-delivery via liposomes. International journal of nanomedicine, 2015, Volume: 10 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Chloroquine; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Liposomes; Mice; Paclitaxel; Tissue Distribution	2015
Anti-malarial Drugs Primaquine and Chloroquine Have Different Sensitization Effects with Anti-mitotic Drugs in Resistant Cancer Cells. Anticancer research, 2016, Volume: 36, Issue:4 Topics: Antimalarials; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chloroquine; Docetaxel; Drug Resistance, Neoplasm; Humans; Mitosis; Paclitaxel; Primaquine; Taxoids; Vinblastine; Vinorelbine	2016
Autophagy inhibition with chloroquine reverts paclitaxel resistance and attenuates metastatic potential in human nonsmall lung adenocarcinoma A549 cells via ROS mediated modulation of β-catenin pathway. Apoptosis : an international journal on programmed cell death, 2019, Volume: 24, Issue:5-6 Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; beta Catenin; Cell Cycle Checkpoints; Cell Line; Cell Survival; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Mitochondria; Neoplastic Stem Cells; Paclitaxel; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Wnt Signaling Pathway	2019
Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis. Cell death & disease, 2019, 12-20, Volume: 10, Issue:12 Topics: Autophagy; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chloroquine; Drug Resistance, Neoplasm; Endothelial Cells; Female; Humans; Lymphatic Metastasis; Lysosomes; Paclitaxel; Proto-Oncogene Proteins c-akt; Sentinel Lymph Node	2019
The nanoparticle-facilitated autophagy inhibition of cancer stem cells for improved chemotherapeutic effects on glioblastomas. Journal of materials chemistry. B, 2019, 03-28, Volume: 7, Issue:12 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line; Cell Survival; Chloroquine; Drug Delivery Systems; Folic Acid; Glioblastoma; Humans; Mice; Nanoparticles; Neoplastic Stem Cells; Paclitaxel; Serum Albumin, Bovine	2019
Enhanced lysosomal function is critical for paclitaxel resistance in cancer cells: reversed by artesunate. Acta pharmacologica Sinica, 2021, Volume: 42, Issue:4 Topics: Antineoplastic Agents; Artesunate; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cathepsins; Cell Death; Cell Line, Tumor; Cell Proliferation; Chloroquine; Chromans; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Gene Knockdown Techniques; Humans; Lysosomes; Paclitaxel	2021
KRAS-dependent cancer cells promote survival by producing exosomes enriched in Survivin. Cancer letters, 2021, 10-01, Volume: 517 Topics: Cell Communication; Cell Line, Tumor; Cell Survival; Chloroquine; Exosomes; Extracellular Vesicles; Fibroblasts; Humans; Imidazoles; Mutation; Naphthoquinones; Paclitaxel; Pancreas; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Survivin	2021
Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models. Journal of translational medicine, 2022, 06-27, Volume: 20, Issue:1 Topics: Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Chloroquine; Drug Resistance, Neoplasm; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Triple Negative Breast Neoplasms	2022
Combination of Antimalarial and CNS Drugs with Antineoplastic Agents in MCF-7 Breast and HT-29 Colon Cancer Cells: Biosafety Evaluation and Mechanism of Action. Biomolecules, 2022, Oct-16, Volume: 12, Issue:10 Topics: Adenosine Diphosphate; Antimalarials; Antineoplastic Agents; Artesunate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benztropine; Breast Neoplasms; Cell Line, Tumor; Chloroquine; Colonic Neoplasms; Containment of Biohazards; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Fluoxetine; Fluphenazine; Humans; Ki-67 Antigen; MCF-7 Cells; Michigan; NF-kappa B; Paclitaxel; Poly(ADP-ribose) Polymerase Inhibitors; Ribose; Sertraline; Thioridazine	2022
Chloroquine Sensitizes Esophageal Carcinoma EC109 Cells to Paclitaxel by Inhibiting Autophagy. Critical reviews in eukaryotic gene expression, 2023, Volume: 33, Issue:6 Topics: Apoptosis; Autophagy; Carcinoma; Cell Line, Tumor; Cell Proliferation; Chloroquine; Esophageal Neoplasms; Humans; Paclitaxel; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases	2023