chloroquine and nifurtimox

chloroquine has been researched along with nifurtimox in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (42.11)29.6817
2010's11 (57.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Figadère, B; Fournet, A; Franck, X; Hocquemiller, R; Mahieux, R; Prina, E1
Capson, TL; Gonzalez, J; Gutiérrez, M; Guzman, HM; Ortega-Barría, E; Quiñoa, E; Riguera, R1
Engene, N; Gerwick, L; Gerwick, WH; Ortega-Barría, E; Romero, LI; Simmons, TL; Ureña, LD1
Coley, PD; Cubilla-Rios, L; Della-Togna, G; Gerwick, WH; Kursar, TA; Martínez-Luis, S1
Almanza, A; Clark, BR; Gerwick, WH; Kyle, DE; Linington, RG; Trimble, EE; Ureña, LD1
Alvarez, DE; Boiani, L; Bollini, M; Bruno, AM; Casal, JJ; Cerecetto, H; González, M1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Balunas, MJ; Fenner, AM; Gerwick, WH; Kyle, DE; Linington, RG; Tidgewell, K; Togna, GD; Ureña, LD1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Della Togna, G; Gerwick, WH; Kyle, DE; Linington, RG; Lopez, D; Sanchez, LM; Vesely, BA1
Arán, VJ; Barigye, SJ; Cabrera-Serra, MG; Chicharro, R; Escario, JA; Garcia-Domenech, R; García-Sánchez, RN; Gómez-Barrio, A; Ibarra-Velarde, F; Lopez-Arencibia, A; Lorenzo-Morales, J; Machado Tugores, Y; Marrero-Ponce, Y; Martín-Navarro, C; Martínez-Fernández, AR; Martins Alho, MA; Meneses-Marcel, A; Mondragón, M; Mondragón, R; Montero-Torres, A; Nogal, JJ; Pérez-Giménez, F; Piñero, J; Rivera, N; Rolón, M; Tytgat, J; Vega, MC1
Ariën, KK; Augustyns, K; Cos, P; Dirié, B; Heeres, J; Joossens, J; Lewi, PJ; Lyssens, S; Maes, L; Michiels, J; Van der Veken, P; Vanham, G; Venkatraj, M1
Aguilar-Suárez, R; Correa-Basurto, J; Galindo-Sevilla, N; Hernández-Luis, F; Márquez-Navarro, A; Mendoza-Martínez, C; Montero-Cortes, MD; Nieto-Meneses, R; Nogueda-Torres, B; Rodriguez-Lezama, A; Rojas-Rojas, Á; Suárez-Contreras, E1
Bosc, D; Cojean, S; Dubois, J; Franco, CH; Freitas-Junior, LH; Grellier, P; Loiseau, PM; Moraes, CB; Mouray, E1
Augustyns, K; Caljon, G; Heeres, J; Joossens, J; Lewi, PJ; Maes, L; Salado, IG; Van der Veken, P; Venkatraj, M1
Augustyns, K; Baán, A; Caljon, G; Kiekens, F; Maes, L; Matheeussen, A; Salado, IG; Van der Veken, P; Verdeyen, T1

Other Studies

19 other study(ies) available for chloroquine and nifurtimox

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Biological evaluation of substituted quinolines.
    Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14

    Topics: Animals; Antiparasitic Agents; Cell Line; Cell Transformation, Viral; Evaluation Studies as Topic; HTLV-I Infections; Leishmania; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Trypanosoma

2004
Antiplasmodial metabolites isolated from the marine octocoral Muricea austera.
    Journal of natural products, 2006, Volume: 69, Issue:10

    Topics: Animals; Anthozoa; Antimalarials; Antiprotozoal Agents; Drug Resistance, Microbial; Marine Biology; Microbial Sensitivity Tests; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Steroids; Trypanosoma cruzi; Tyramine

2006
Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis.
    Journal of natural products, 2008, Volume: 71, Issue:9

    Topics: Animals; Antiprotozoal Agents; Cyanobacteria; Depsipeptides; Leishmania mexicana; Marine Biology; Molecular Structure; Panama; Plasmodium falciparum; Trypanosoma cruzi

2008
Antileishmanial constituents of the Panamanian endophytic fungus Edenia sp.
    Journal of natural products, 2008, Volume: 71, Issue:12

    Topics: Animals; Antiprotozoal Agents; Ascomycota; Heterocyclic Compounds, 4 or More Rings; Leishmania donovani; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Panama; Plasmodium falciparum; Spiro Compounds

2008
Antimalarial peptides from marine cyanobacteria: isolation and structural elucidation of gallinamide A.
    Journal of natural products, 2009, Volume: 72, Issue:1

    Topics: Animals; Antimalarials; Antimicrobial Cationic Peptides; Caribbean Region; Chloroquine; Cyanobacteria; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Peptides; Plasmodium falciparum

2009
New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: biological evaluation and structure-activity relationships.
    Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4

    Topics: Animals; Chagas Disease; DNA, Protozoan; Dose-Response Relationship, Drug; Glutathione; HeLa Cells; Humans; Imidazoles; Isoquinolines; Models, Molecular; Oxidation-Reduction; Quantitative Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2009
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
    Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18

    Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity.
    Journal of natural products, 2010, Volume: 73, Issue:1

    Topics: Animals; Antiprotozoal Agents; Chloroquine; Drug Resistance; Inhibitory Concentration 50; Leishmania donovani; Lyngbya Toxins; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Parasitic Sensitivity Tests; Plasmodium falciparum

2010
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids.
    Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

    Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds.
    Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10

    Topics: Antiprotozoal Agents; Cyanobacteria; Leishmania donovani; Lipopeptides; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship

2010
Antiprotozoan lead discovery by aligning dry and wet screening: prediction, synthesis, and biological assay of novel quinoxalinones.
    Bioorganic & medicinal chemistry, 2014, Mar-01, Volume: 22, Issue:5

    Topics: Antiprotozoal Agents; Cyclization; Molecular Structure; Quantitative Structure-Activity Relationship; Quinoxalines

2014
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.
    Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19

    Topics: Anti-HIV Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense

2014
Design, synthesis and biological evaluation of quinazoline derivatives as anti-trypanosomatid and anti-plasmodial agents.
    European journal of medicinal chemistry, 2015, Volume: 96

    Topics: Administration, Oral; Animals; Antimalarials; Antiprotozoal Agents; Chlorocebus aethiops; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Female; Leishmania major; Malaria; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium vivax; Quinazolines; Structure-Activity Relationship; Trypanosoma cruzi; Vero Cells

2015
Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors.
    European journal of medicinal chemistry, 2016, Feb-15, Volume: 109

    Topics: Alkyl and Aryl Transferases; Animals; Antiparasitic Agents; Cell Line; Enzyme Inhibitors; Humans; Imidazoles; Leishmania donovani; Leishmaniasis, Visceral; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis

2016
Novel triazine dimers with potent antitrypanosomal activity.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Animals; Antiprotozoal Agents; Cell Proliferation; Cell Survival; Dimerization; Dose-Response Relationship, Drug; Drug Discovery; Fibroblasts; Humans; Leishmania infantum; Male; Mice; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazines; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosoma cruzi

2018
Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Disease Models, Animal; Humans; Mice; Structure-Activity Relationship; Triazines; Tropolone; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2018