chloroquine and morphine

chloroquine has been researched along with morphine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19909 (40.91)18.7374
1990's0 (0.00)18.2507
2000's7 (31.82)29.6817
2010's6 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Famaey, JP; Fontaine, J; Reuse, J1
Mardones, J; Sanchez, E; Tampier, L1
Oldendorf, WH1
Irey, NS1
Hasegawa, AT; Peterson, RE; Roerig, DL; Wang, RI1
Froede, RC; Irey, NS1
Deaton, JG1
Graeme, ML; John, M; Sigg, EB1
Ajayi, AA; Onigbogi, O; Ukponmwan, OE1
MASON, RM1
Lim, G; Mao, J; Sung, B; Wang, S; Yang, L1
Giesler, GJ; Moser, HR1

Reviews

1 review(s) available for chloroquine and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

21 other study(ies) available for chloroquine and morphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Inhibiting effects of morphine, chloroquine, nonsteroidal and steroidal anti-inflammatory drugs on electrically-induced contractions of guinea-pig ileum and the reversing effect of prostaglandins.
    Agents and actions, 1975, Volume: 5, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Chloroquine; Drug Interactions; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Prostaglandins E

1975
Effects of chloroquine pretreatment on lethal dose of morphine and on morphine metabolism in rats.
    European journal of pharmacology, 1969, Volume: 7, Issue:1

    Topics: Animals; Chloroquine; Glucuronates; Liver; Male; Morphine; NAD; Rats; Uracil Nucleotides

1969
Brain uptake of metabolites and drugs following carotid arterial injections.
    Transactions of the American Neurological Association, 1971, Volume: 96

    Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats

1971
Blood and tissue concentrations of drugs associated with fatalities.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Adolescent; Adult; Age Factors; Autopsy; Barbiturates; Brain Chemistry; Bronchopneumonia; Child; Chloroquine; Dextropropoxyphene; Drug Interactions; Female; Glutethimide; Humans; Kidney; Liver; Male; Meprobamate; Methadone; Morphine; Salicylates; Sex Factors; Substance-Related Disorders

1974
Effect of chloroquine and phenobarbital on morphine glucuronidation and biliary excretion in the rat.
    Biochemical pharmacology, 1974, Apr-15, Volume: 23, Issue:8

    Topics: Animals; Bile; Carbon Radioisotopes; Catheterization; Chloroquine; Glucuronates; Injections, Intravenous; Male; Morphine; Phenobarbital; Rats; Time Factors

1974
Evaluation of deaths from drug overdose. A clinicopathologic study.
    American journal of clinical pathology, 1974, Volume: 61, Issue:6

    Topics: Accidents; Adolescent; Adult; Aged; Barbiturates; Child; Chloroquine; Dextropropoxyphene; Female; Glutethimide; Humans; Male; Meprobamate; Methadone; Middle Aged; Morphine; Poisoning; Pulmonary Edema; Salicylates; Suicide

1974
Fatal pulmonary edema as a complication of acute falciparum malaria.
    The American journal of tropical medicine and hygiene, 1970, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Cephalosporins; Chloroquine; Digitalis Glycosides; Humans; Hypersensitivity; Malaria; Male; Meperidine; Morphine; Penicillins; Plasmodium falciparum; Pulmonary Edema; Pyrimethamine; Quinine; Radiography; Sulfisoxazole; Vietnam

1970
Induction of periarthritis by oral administration of 6-sulfanilamidoindazole and its treatment in rats.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1

    Topics: Animals; Aspirin; Chloroquine; Cloxacillin; Hydralazine; Hydrocortisone; Indomethacin; Male; Mercaptopurine; Methotrexate; Morphine; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Periarthritis; Phenylbutazone; Rats; Sulfinpyrazone; Sulfonamides

1967
Mechanisms of chloroquine-induced body-scratching behavior in rats: evidence of involvement of endogenous opioid peptides.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:2

    Topics: Animals; Antimalarials; Chloroquine; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Opioid Peptides; Pruritus; Rats

2000
USE OF DRUGS IN THE TREATMENT OF RHEUMATOID ARTHRITIS.
    Physiotherapy, 1964, Volume: 50

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Aspirin; Chloroquine; Codeine; Humans; Hydroxychloroquine; Methadone; Morphine; Oxyphenbutazone; Phenylbutazone; Toxicology

1964
Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation.
    The Journal of biological chemistry, 2008, Aug-01, Volume: 283, Issue:31

    Topics: Acetylcysteine; Amino Acid Transport System X-AG; Analgesics, Opioid; Animals; Chloroquine; Excitatory Amino Acid Transporter 3; Humans; Leupeptins; Male; Morphine; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Ubiquitin

2008
Itch and analgesia resulting from intrathecal application of morphine: contrasting effects on different populations of trigeminothalamic tract neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Apr-03, Volume: 33, Issue:14

    Topics: Action Potentials; Analgesics, Opioid; Animals; Antirheumatic Agents; Chloroquine; Electric Stimulation; Histamine; Injections, Spinal; Male; Morphine; Neural Pathways; Pain; Peptide Fragments; Pruritus; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin; Stimulation, Chemical; Thalamus; Trigeminal Nuclei

2013