chloroquine has been researched along with monensin in 194 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 86 (44.33) | 18.7374 |
| 1990's | 79 (40.72) | 18.2507 |
| 2000's | 19 (9.79) | 29.6817 |
| 2010's | 9 (4.64) | 24.3611 |
| 2020's | 1 (0.52) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Thomas, SC; Warhurst, DC | 1 |
| Kawahara, N; Kiyotani, K; Nagai, Y; Sakaguchi, T; Yang, XZ; Yoshida, T | 1 |
| Daniel, JC; Lecerf, JM; Levy, SB; Slapak, CA | 1 |
| Bacic, M; Chen, C; Lebovics, RS; Lesch, KP; Merrill, MJ; Sunderland, T; Wolozin, B | 1 |
| Murata, M; Ohashi, M; Ohnishi, S | 1 |
| de Chastellier, C; Rabinovitch, M; Veras, PS | 1 |
| Engleman, EG; Rajasekar, S; Ruegg, CL; Stein, BS | 1 |
| Pulido, R; Sánchez-Madrid, F | 1 |
| Buxbaum, JD; Caporaso, GL; Gandy, SE; Greengard, P | 1 |
| Endo, A; Hasumi, K; Naganuma, S; Shinohara, C | 1 |
| Spear, PG; Wittels, M | 1 |
| Sathre, KA; Steer, CJ; Tsang, ML; Weatherbee, JA | 1 |
| Gibson, S; Schwartz, J; White, A | 1 |
| Duff, GW; Symons, JA | 1 |
| Amitay, R; Bar-Nun, S; Haimovich, J; Rabinovich, E; Shachar, I | 1 |
| Berman, J; Nichols, JS; Wiseman, JS; Wypij, DM | 1 |
| Chen, SS | 1 |
| Kovacina, KS; Lioubin, MN; Madisen, L; Marquardt, H; Purchio, AF; Roth, R | 1 |
| Lear, MC; McAbee, DD; Weigel, PH | 1 |
| Bachhawat, AK; Pillai, S | 1 |
| Mortensen, RF; Tebo, JM | 1 |
| Blomgren, K; Thyberg, J | 1 |
| Fishman, PH; Pacuszka, T | 1 |
| Enomoto, K; Kaneko, A; Mori, M; Oyamada, M; Yamaguchi, J | 1 |
| Augustine, EC; Kensinger, RS | 1 |
| Juliano, RL; Sczekan, MM | 1 |
| DiCioccio, RA; Mahoney, CM | 1 |
| Goldberg, IJ; Klein, MG; Saxena, U | 1 |
| Gollapudi, S; Gupta, S; Ohira, K; Vayuvegula, B | 1 |
| Clarke, BL; McAbee, DD; Oka, JA; Weigel, PH | 1 |
| Furlanetto, RW | 1 |
| Jarett, L; Smith, RM | 1 |
| Gromeier, M; Wetz, K | 1 |
| Donovan, MG; Storm, DR | 1 |
| Clem, LW; Jørgensen, T; Miller, NW; Vallejo, AN | 1 |
| Odum, L; Rehfeld, JF | 1 |
| Anderson, SK; DeSantes, K; Geissler, F; Press, OW | 1 |
| Beug, H; Birnstiel, ML; Cotten, M; Kirlappos, H; Längle-Rouault, F; Mechtler, K; Wagner, E; Zenke, M | 1 |
| Blomhoff, JP; Letnes, H; Stray, N | 1 |
| Derksen, JT; Dijkstra, J; Roerdink, FH; Scherphof, GL; Spanjer, HH | 1 |
| Knecht, TP; Pittman, RC; Rosenbaum, MS; Taylor, CA | 1 |
| De Lisle, RC; Williams, JA | 1 |
| Amara, JF; Lederkremer, G; Lodish, HF | 1 |
| Adorini, L; Appella, E; Cardinaux, F; Doria, G; Nagy, ZA | 1 |
| Cantin, M; Murthy, KK; Thibault, G | 1 |
| Hameed, A; Lee, MK; Lichtenheld, MG; Olsen, KJ; Podack, ER | 1 |
| Rizzolo, LJ | 1 |
| Chapman, SJ; Walsh, A | 1 |
| Clarke, BL; Weigel, PH | 1 |
| Broxterman, HJ; Kuiper, CM; Lankelma, J; Pinedo, HM; Schuurhuis, GJ | 1 |
| McAbee, DD; Oka, JA; Weigel, PH | 1 |
| Bland, PW; Whiting, CV | 1 |
| Mahmalgi, J; Moreau, S; Prensier, G; Veignie, E | 1 |
| Kondor-Koch, C; Parczyk, K | 1 |
| Stenseth, K; Thyberg, J | 1 |
| Deepe, GS; Harris, JE | 1 |
| Humphreys, RE; Knapp, W; Nguyen, QV; Thomas, LJ | 1 |
| Bjørneboe, A; Bjørneboe, GE; Drevon, CA; Hagen, BF; Nossen, JO | 1 |
| Hazum, E; Schvartz, I | 1 |
| Arnljots, K; Lantz, M; Olsson, I; Persson, AM | 1 |
| Cheng, B; Horst, IA; Kowal, J | 1 |
| Betancourt, S; Hadley, G; Jun, S; Nairn, R; Solvay, MJ; Thomas, DW | 1 |
| McClain, DA; Olefsky, JM | 1 |
| Clot, JP; Desbuquois, B; Janicot, M | 1 |
| Koppold, A; Raue, F; Schneider, HG; Ziegler, R; Zink, A | 1 |
| Bradshaw, RA; Eveleth, DD | 1 |
| Habermehl, KO; Wetz, K; Willingmann, P; Zeichhardt, H | 1 |
| Kelly, B; Massagué, J | 1 |
| Bülow, R; Nonnengässer, C; Overath, P | 1 |
| Glushakova, SE; Lukashevich, IS | 1 |
| Humphreys, RE; Knapp, W; Nguyen, QV | 1 |
| Hedin, U; Thyberg, J | 1 |
| Carpentier, JL; Hachiya, HL; King, GL | 1 |
| Braulke, T; Gartung, C; Hasilik, A; von Figura, K | 1 |
| Arnaud, CD; Nyiredy, KO; Silve, CM; Teitelbaum, AP | 1 |
| Brown, MS; Davis, CG; Elhammer, A; Goldstein, JL; Kornfeld, S; Russell, DW; Schneider, WJ | 1 |
| Olsson, I; Persson, AM; Strömberg, K | 1 |
| Akin, DT; Kinkade, JM | 1 |
| Baxt, B | 1 |
| Amson, RB; Galand, P; Mosselmans, R; Romasco, F; Telerman, A; Wybran, J | 1 |
| Braulke, T; Geuze, HJ; Hasilik, A; Slot, JW; von Figura, K | 1 |
| Fambrough, DM; Lippincott-Schwartz, J | 1 |
| Finbloom, DS | 2 |
| Amano, J; Kato, K; Nishimura, Y; Sato, H; Tsuji, H | 1 |
| Florin, I; Henriques, B; Thelestam, M | 1 |
| Izzo, RS; Pellecchia, C; Praissman, M | 1 |
| Smedsrød, B | 1 |
| Ames, RS; Fry, K; Lee, HM; Roth, JA; Scannon, PJ | 1 |
| Christoffersen, T; Gladhaug, IP | 1 |
| Bauer, A; Kirchner, H; Rutenfranz, I | 1 |
| Levy, JR; Olefsky, JM | 1 |
| Blum, JS; Cresswell, P | 1 |
| Ali, M; Plas, C; Soubigou, P | 1 |
| Bednarczyk, JL; Capra, JD | 1 |
| Bottger, BA; Sjölund, M; Thyberg, J | 1 |
| Anderson, RG; Kamen, BA; Peryea, X; Streckfuss, AJ; Wang, MT | 1 |
| Cooper, JL; Selinfreund, R; Wakshull, E; Wharton, W | 1 |
| Akiyama, T; Matsumoto, J; Oikawa, A; Saeki, H | 1 |
| Brandenberg, D; Heidenreich, KA; Huecksteadt, T; Olefsky, JM | 1 |
| Banskota, NK; Carpentier, JL; King, GL | 1 |
| Blake, AD; Strader, CD | 1 |
| Drevon, CA; Nossen, JO; Rustan, AC; Tefre, T | 1 |
| Benacerraf, B; Falo, LD; Rock, KL; Rothstein, L | 1 |
| Mørland, B | 1 |
| Colofiore, JR; Schwartz, ER | 1 |
| Kono, T; Robinson, FW; Smith, MM; Ueda, M | 1 |
| Schulz, MF; Thorens, B; Vassalli, P | 1 |
| Den, H | 1 |
| Bensch, KG; Stein, BS; Sussman, HH | 1 |
| Chang, TM; Kullberg, DW | 1 |
| Maxfield, FR | 1 |
| Ashwell, G; Harford, J; Klausner, RD; Wolkoff, AW | 1 |
| Carpenter, G; Stoscheck, CM | 1 |
| Fitzgerald, DJ; Pastan, I; Seth, P; Willingham, MC | 1 |
| Berkower, IJ; Berzofsky, JA; Busch, M; Gurd, FR; Streicher, HZ | 1 |
| Cabantchik, ZI; Ginsburg, H; Yayon, A | 1 |
| Bystryn, JC; Johnston, D | 1 |
| Fujimori, K; Imai, K; Takano, Y; Tanaka, A; Yamada, M; Yamamoto, K | 1 |
| Hare, JF; Huston, M | 1 |
| Gollapudi, SV; Kern, M; Ramanadham, M | 1 |
| Berry, RW; Yates, ME | 1 |
| Kääriäinen, L; Korpela, K; Pesonen, M; Saraste, J; Ukkonen, P | 1 |
| Chesnut, RW; Colon, SM; Grey, HM | 1 |
| Bunnett, NW; Garland, AM; Grady, EF; Payan, DG; Vigna, SR | 1 |
| Breuer, W; Cabantchik, ZI; Epsztejn, S | 1 |
| Andersson, LM; Warburton, MJ | 1 |
| Bächi, T; Berger, EG; Bosshart, H; Grimm, K; Kleene, R; Watzele, M | 1 |
| Ikeda, T; Ishigami, M; Shinozaki, N; Shiraishi, A; Takatori, T; Tokui, T; Tsuruo, T | 1 |
| Henderson, KG; Muller, HK; Qu, M; Woods, GM | 1 |
| Hunt, CA; Weiss, TL; Wu-Pong, S | 1 |
| Mendez, AJ | 1 |
| Carrasco, L; Pérez, L | 2 |
| Deichen, JT; Greten, H; Jäckle, S; Rinninger, F; Windler, E | 1 |
| Esko, JD; Hager, KM; Hajduk, SL; Moore, DR; Pierce, MA; Tytler, EM | 1 |
| Dams, E; De Wolf, MJ; Dierick, WS | 1 |
| Boeyé, A; Kronenberger, P; Vrijsen, R | 1 |
| Dash, PK; Moore, AN | 1 |
| Friedrich, F; Häussinger, D; Lang, F; Völkl, H | 1 |
| Block, MR; Marie, C; Tranqui, L; Usson, Y | 1 |
| Curran, PK; Fishman, PH; Orlandi, PA | 1 |
| Adams, PC; Chau, LA | 1 |
| Marcil, J; Ravindranath, N; Sairam, MR | 1 |
| Barbieri, JT; Xu, Y | 1 |
| Anderson, RG; Mineo, C | 1 |
| Balkenende, AY; Slaper-Cortenbach, IC; van den Berg, H; van der Schoot, CE; Van Leeuwen, EF; Vervoordeldonk, SF; von dem Borne, AE | 1 |
| Frey, TK; Macchia, S; Mastromarino, P; Orsi, N; Petruzziello, R; Rieti, S | 1 |
| Beers, MF | 1 |
| Duan, H; Lange, Y; Mazzone, T | 1 |
| Buchmeier, MJ; Gallagher, TM; Nash, TC | 1 |
| Pless, DD; Wellner, RB | 1 |
| Dayer, JM; Galve-de Rochemonteix, B; Nicod, LP | 1 |
| Adovelande, J; Schrével, J | 1 |
| Antia, NH; Birdi, TJ; D'Souza, S | 1 |
| Buchmeier, MJ; Nash, TC | 1 |
| DeLuca, A; Eckhardt, AE; Hill, RL; Perez-Vilar, J | 1 |
| Bernardes, C; Cruz, B; Geraldes, A; Valdeira, ML | 1 |
| Fasolato, C; Pozzan, T; Scheenen, WJ; Wollheim, CB | 1 |
| Benedetti, PA; Brunori, M; Citro, G; D'Agostino, I; Ginobbi, P; Ippoliti, R; Lendaro, E; Ombres, D | 1 |
| Ishiura, S; Kinouchi, T; Kouchi, Z; Sorimachi, H; Suzuki, K | 1 |
| Dittmer, F; von Figura, K | 1 |
| Everitt, E; Rodríguez, E | 1 |
| Alonso, MA; Puertollano, R | 1 |
| Akisaka, T; Inoue, M; Yoshida, H | 1 |
| George, AL; Hu, N; Murray, KT; Yi, J; Zhou, J | 1 |
| Nolan, DP; Voorheis, HP | 1 |
| O'Brien, PJ; Pourahmad, J; Ross, S | 1 |
| Al-Damluji, S; Shen, WB | 1 |
| Dodds, RA; Drake, FH; Gowen, M; Holmes, MW; Hwang, SM; James, IE; McClung, HA; Rieman, DJ | 1 |
| Egan, J; Hoppe, HC; Meredith, SA; van Schalkwyk, DA; Weber, BW; Wiehart, UI | 1 |
| Gorelick, FS; Kolodecik, TR; Thrower, EC; Waterford, SD | 1 |
| Dwek, RA; Negroiu, G; Petrescu, SM | 1 |
| Braun, NA; Fazio, S; Hasty, AH; Linton, MF; Mohler, PJ; Su, YR; Swift, LL; Weisgraber, KH; Yancey, PG | 1 |
| Kang, SK; Kim, CH; Kim, YH; Park, YG | 1 |
| Moghimi, HR; Shirazi, FH; Tamaddon, AM | 1 |
| Laggner, H; Neuhofer, A; Pagler, TA; Stangl, H; Strobl, W | 1 |
| Adachi, K; Ichinose, T; Kitazato, K; Kobayashi, N; Takizawa, N; Watanabe, K | 1 |
| Martin-Armas, M; Smedsrød, B; Sommer, AI | 1 |
| Delputte, PL; Misinzo, G; Nauwynck, HJ | 1 |
| Delputte, PL; Lefebvre, DJ; Misinzo, G; Nauwynck, HJ | 1 |
| Babochkina, TI; Laktionov, PP; Morozkin, ES; Vlassov, VV | 1 |
| Basyuk, E; Berlioz-Torrent, C; Bertrand, E; Camus, G; Kjems, J; Molle, D; Segura-Morales, C | 1 |
| Chi, C; Han, M; Wu, X; Xu, T; Zhu, H; Zhuang, Y | 1 |
| Ashraf, S; Gil, PR; Nazarenus, M; Parak, WJ | 1 |
| Kim, HW; Lee, Y; Lim, J; Oh, MS; Oh, YJ; Rhyu, IJ; Youdim, MB; Yue, Z | 1 |
| Muñoz-Barroso, I; Sánchez-Felipe, L; Villar, E | 1 |
| Florey, O; Gammoh, N; Jiang, X; Kim, SE; Overholtzer, M | 1 |
| He, CY; Li, FJ | 1 |
| Abuznait, AH; Alam, K; Ding, K; Li, L; Pahwa, S; Wang, X; Yue, W; Zhang, P | 1 |
| Baska, KS; Dalal, S; Dhingra, SK; Fidock, DA; Garcia, CRS; Klein, MS; Klemba, M; Krishna, S; Lee, AH; Lewis, IA; Llinás, M; Roepe, PD; Rubiano, K; Singh, MK; Siriwardana, A | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, J; Chen, W; Choudhry, N; Xu, D; Yang, Z; Zanin, M; Zhao, X | 1 |
2 review(s) available for chloroquine and monensin
| Article | Year |
|---|---|
MHVR-independent cell-cell spread of mouse hepatitis virus infection requires neutral pH fusion.
Topics: Animals; Antibodies, Monoclonal; Carcinoembryonic Antigen; Cell Adhesion Molecules; Cell Fusion; Cell Line; Chloroquine; Glycoproteins; Hydrogen-Ion Concentration; Lysosomes; Mice; Monensin; Murine hepatitis virus | 1995 |
Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Topics: Antiviral Agents; China; Coronavirus Protease Inhibitors; COVID-19; COVID-19 Drug Treatment; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; SARS-CoV-2; Small Molecule Libraries | 2020 |
192 other study(ies) available for chloroquine and monensin
| Article | Year |
|---|---|
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
The chemotherapy of rodent malaria, XXXI. The effect of some metabolic inhibitors upon chloroquine-induced pigment clumping (CIPC) in Plasmodium berghei.
Topics: Animals; Antimetabolites; Chloroquine; Dicyclohexylcarbodiimide; Dose-Response Relationship, Drug; Mice; Monensin; Oligomycins; Pigments, Biological; Plasmodium berghei; Valinomycin; Venturicidins | 1978 |
Distribution and substrate specificity of intracellular proteolytic processing enzyme(s) for paramyxovirus fusion glycoproteins.
Topics: Calcimycin; Cell Line; Chloroquine; Endopeptidases; Membrane Proteins; Monensin; Newcastle disease virus; Parainfluenza Virus 3, Human; Paramyxoviridae; Protein Precursors; Protein Processing, Post-Translational; Serine Endopeptidases; Substrate Specificity; Viral Fusion Proteins; Virulence; Virus Activation | 1992 |
Energy-dependent accumulation of daunorubicin into subcellular compartments of human leukemia cells and cytoplasts.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Compartmentation; Chloroquine; Daunorubicin; Deoxyglucose; Dinitrophenols; Drug Interactions; Drug Resistance; Energy Metabolism; Ethylmaleimide; Humans; Leukemia; Membrane Glycoproteins; Methylamines; Microscopy, Fluorescence; Monensin; Ouabain; Sodium Azide; Tumor Cells, Cultured; Vanadates; Verapamil | 1992 |
Differential expression of carboxyl terminal derivatives of amyloid precursor protein among cell lines.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Antimetabolites; Cell Line; Chloroquine; Humans; Immunoblotting; Immunohistochemistry; Lysosomes; Monensin; Neurons | 1992 |
A novel fluorescence method to monitor the lysosomal disintegration of low density lipoprotein.
Topics: Animals; Cell Separation; Chloroquine; Endocytosis; Flow Cytometry; Fluorescent Dyes; Lipoproteins, LDL; Lysosomes; Monensin; Nocodazole | 1992 |
Transfer of zymosan (yeast cell walls) to the parasitophorous vacuoles of macrophages infected with Leishmania amazonensis.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Cytochalasin D; Hydrogen-Ion Concentration; Kinetics; Leishmaniasis; Macrophages; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron; Monensin; Temperature; Vacuoles; Zymosan | 1992 |
Degradation of CD4 following phorbol-induced internalization in human T lymphocytes. Evidence for distinct endocytic routing of CD4 and CD3.
Topics: Alkaloids; Ammonium Chloride; CD4 Antigens; Chloroquine; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Monensin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Radioimmunoprecipitation Assay; Staurosporine; T-Lymphocytes | 1992 |
Glycosylation of CD45: carbohydrate processing through Golgi apparatus is required for cell surface expression and protein stability.
Topics: Antigens, CD; Cell Membrane; Cells, Cultured; Chloroquine; Glycosylation; Histocompatibility Antigens; Humans; In Vitro Techniques; Leukocyte Common Antigens; Molecular Weight; Monensin; Protein Processing, Post-Translational; Tunicamycin | 1992 |
Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.
Topics: Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Bacterial Agents; Autoradiography; Brefeldin A; Chloroquine; Cyclopentanes; Glycosylation; Kinetics; Methionine; Molecular Weight; Monensin; Organelles; PC12 Cells; Protein Processing, Post-Translational; Sulfur Radioisotopes; Time Factors | 1992 |
Inhibition of the uptake of oxidized low-density lipoprotein in macrophage J774 by the antibiotic ikarugamycin.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Biological Transport; Carbon Radioisotopes; Cell Line; Chloroquine; Humans; Iodine Radioisotopes; Kinetics; Lactams; Lipoproteins, LDL; Macrophages; Mice; Monensin; Oleic Acid; Oleic Acids; Oxidation-Reduction; Receptors, LDL | 1992 |
Penetration of cells by herpes simplex virus does not require a low pH-dependent endocytic pathway.
Topics: Adsorption; Amantadine; Animals; Chloroquine; Colchicine; Concanavalin A; Cytochalasin B; Dithiothreitol; Endocytosis; Heparin; Hydrogen-Ion Concentration; Microscopy, Electron; Monensin; Simplexvirus; Trifluoperazine; Tumor Cells, Cultured; Vero Cells; Vesicular stomatitis Indiana virus; Viral Plaque Assay; Wheat Germ Agglutinins | 1991 |
Binding and internalization of transforming growth factor-beta 1 by human hepatoma cells: evidence for receptor recycling.
Topics: Binding, Competitive; Carcinoma, Hepatocellular; Chloroquine; Cycloheximide; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Monensin; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured | 1991 |
Regulation of ACTH secretory pathways in cultured pituitary cells.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Cells, Cultured; Chloroquine; Immunoradiometric Assay; Monensin; Pituitary Gland; Vinblastine | 1991 |
A soluble form of the interleukin-1 receptor produced by a human B cell line.
Topics: Aprotinin; B-Lymphocytes; Cell Line; Chloroquine; Cycloheximide; Dactinomycin; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Humans; Interleukin-1; Kinetics; Monensin; Protease Inhibitors; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins | 1990 |
Post-translational regulation of IgM expression in B lymphocytes. Selective nonlysosomal degradation of assembled secretory IgM is temperature-dependent and occurs prior to the trans-Golgi.
Topics: Animals; B-Lymphocytes; Blotting, Northern; Chloroquine; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Golgi Apparatus; Hexosaminidases; Immunoglobulin M; Lymphoma, B-Cell; Lysosomes; Mice; Monensin; Precipitin Tests; Protein Processing, Post-Translational; RNA; Temperature; Tumor Cells, Cultured | 1991 |
Evidence against a role for aspartyl proteases in intracellular processing of big endothelin.
Topics: Ammonium Chloride; Aspartic Acid; Aspartic Acid Endopeptidases; Cells, Cultured; Chloroquine; Chromatography, High Pressure Liquid; Endothelin-1; Endothelins; Endothelium; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Monensin; Pepstatins; Protein Precursors | 1991 |
Mechanisms of IgE homeostasis. Sequestration of IgE by murine type II IgE Fc receptor-bearing B cell hybridomas.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Chloroquine; Endocytosis; Homeostasis; Hybridomas; Immunoglobulin E; Lysosomes; Mice; Mice, Inbred BALB C; Monensin; Receptors, Fc; Receptors, IgE | 1991 |
Characterization of latent recombinant TGF-beta 2 produced by Chinese hamster ovary cells.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cell Line; Chloroquine; Chromatography, Gel; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Female; Kinetics; Mannosephosphates; Molecular Sequence Data; Molecular Weight; Monensin; Ovary; Protein Sorting Signals; Receptor, IGF Type 2; Receptors, Cell Surface; Recombinant Proteins; Transfection; Transforming Growth Factor beta | 1991 |
Total cellular activity and distribution of a subpopulation of galactosyl receptors in isolated rat hepatocytes are differentially affected by microtubule drugs, monensin, low temperature, and chloroquine.
Topics: Animals; Asialoglycoproteins; Cells, Cultured; Chloroquine; Colchicine; Galactose; Kinetics; Liver; Male; Microtubules; Monensin; Orosomucoid; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Temperature | 1991 |
Distinct intracellular fates of membrane and secretory immunoglobulin heavy chains in a pre-B cell line.
Topics: Ammonium Chloride; Animals; B-Lymphocytes; Brefeldin A; Cell Line, Transformed; Chloroquine; Cyclopentanes; Immunoglobulin A, Secretory; Immunoglobulin Heavy Chains; Immunoglobulin Isotypes; Kinetics; Lysosomes; Monensin; Receptors, Antigen, B-Cell | 1991 |
Internalization and degradation of receptor bound C-reactive protein by U-937 cells: induction of H2O2 production and tumoricidal activity.
Topics: Ammonium Chloride; C-Reactive Protein; Cell Compartmentation; Cell Death; Cell Differentiation; Cell Line; Chloroquine; Endocytosis; Humans; Hydrogen Peroxide; Monensin; Monocytes; Neoplasms, Experimental; Receptors, Immunologic | 1991 |
Phenotype modulation in primary cultures of rat aortic smooth muscle cells. Effects of drugs that interfere with the functions of the vacuolar system and the cytoskeleton.
Topics: Animals; Aorta; Cell Adhesion; Cell Survival; Cells, Cultured; Chloroquine; Colchicine; Cytochalasins; Cytoskeleton; Male; Microtubules; Monensin; Muscle Development; Muscle, Smooth, Vascular; Nocodazole; Organ Specificity; Rats; Rats, Inbred Strains | 1990 |
Metabolism of cholesterol, phosphatidylethanolamine and stearylamine analogues of GM1 ganglioside by rat glioma C6 cells.
Topics: Amines; Animals; Carbohydrate Sequence; Chloroquine; Cholesterol; G(M1) Ganglioside; Glioma; Molecular Sequence Data; Monensin; Phosphatidylethanolamines; Rats; Tumor Cells, Cultured | 1991 |
Cytochemical examination of the compartments involved in the transcellular transport of horseradish peroxidase in rat hepatocytes.
Topics: 5'-Nucleotidase; Acid Phosphatase; Animals; Biological Transport; Chloroquine; Glucosephosphates; Histocytochemistry; Horseradish Peroxidase; Injections, Intravenous; Liver; Male; Microscopy, Electron; Monensin; Organelles; Rats; Rats, Inbred Strains; Thiamine Pyrophosphatase | 1990 |
Endocytosis and degradation of ovine prolactin by Nb2 lymphoma cells: characterization and effects of agents known to alter prolactin-induced mitogenesis.
Topics: Amiloride; Animals; Calcimycin; Cell Division; Cell Membrane; Chloroquine; Endocytosis; Kinetics; Leupeptins; Lymphoma; Methylamines; Mitosis; Monensin; Prolactin; Rats; Receptors, Prolactin; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Internalization of the fibronectin receptor is a constitutive process.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Chloroquine; Cricetinae; Endocytosis; Female; In Vitro Techniques; Ligands; Monensin; Ovary; Precipitin Tests; Receptors, Fibronectin; Receptors, Immunologic | 1990 |
Effect of glycosylation inhibitors and acidotropic amines on the synthesis, processing, and intracellular-extracellular distribution of alpha-L-fucosidase in B-lymphoblastoid cells.
Topics: 1-Deoxynojirimycin; alpha-L-Fucosidase; Ammonium Chloride; B-Lymphocytes; Cells, Cultured; Chloroquine; Glucosamine; Glucosidases; Glycosylation; Humans; Mannosidases; Monensin; Tunicamycin | 1990 |
Metabolism of endothelial cell-bound lipoprotein lipase. Evidence for heparan sulfate proteoglycan-mediated internalization and recycling.
Topics: Animals; Aorta; Biological Transport; Cattle; Cells, Cultured; Chloroquine; Chondroitin Sulfate Proteoglycans; Cytochalasin B; Endothelium, Vascular; Female; Glycosaminoglycans; Heparan Sulfate Proteoglycans; Heparin; Heparin Lyase; Heparitin Sulfate; Hydrogen-Ion Concentration; Kinetics; Leupeptins; Lipoprotein Lipase; Milk; Monensin; Polysaccharide-Lyases; Protein Binding; Proteoglycans; Swine | 1990 |
Role of monocytes in anti-CD3-induced T-cell DNA synthesis: effect of chloroquine and monensin on anti-CD3-induced human T-cell activation.
Topics: Antibodies, Monoclonal; Antigen-Presenting Cells; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cell Separation; Chloroquine; DNA; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Lymphocyte Activation; Monensin; Monocytes; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; T-Lymphocytes | 1990 |
The surface activity of the same subpopulation of galactosyl receptors on isolated rat hepatocytes is modulated by colchicine, monensin, ATP depletion, and chloroquine.
Topics: Adenosine Triphosphate; Animals; Asialoglycoproteins; Chloroquine; Colchicine; Endocytosis; In Vitro Techniques; Kinetics; Liver; Monensin; Orosomucoid; Rats; Receptors, Cell Surface | 1990 |
Metabolism of photoaffinity-labeled insulin-like growth factor-I receptors by human cells in vitro.
Topics: Affinity Labels; Cell Line; Chloroquine; Humans; Insulin-Like Growth Factor I; Light; Methylamines; Monensin; Photolysis; Receptors, Cell Surface; Receptors, Somatomedin; Somatomedins; Trypsin | 1990 |
Partial characterization of mechanism of insulin accumulation in H35 hepatoma cell nuclei.
Topics: Adenosine Triphosphate; Biological Transport; Carcinoma, Hepatocellular; Cell Nucleus; Chloroquine; Insulin; Liver Neoplasms; Monensin; Nigericin; Osmolar Concentration; Temperature; Tumor Cells, Cultured | 1990 |
Kinetics of poliovirus uncoating in HeLa cells in a nonacidic environment.
Topics: Ammonium Chloride; Cell Transformation, Viral; Chloroquine; Endocytosis; Glutathione; HeLa Cells; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Methylamines; Monensin; Poliovirus; Tritium; Virus Replication | 1990 |
Evidence that the adenylate cyclase secreted from Bordetella pertussis does not enter animal cells by receptor-mediated endocytosis.
Topics: Adenylyl Cyclases; Ammonium Chloride; Animals; Biological Transport; Bordetella pertussis; Cell Line; Chloroquine; Endocytosis; Kinetics; Mice; Monensin; Neuroblastoma; Receptors, Cell Surface; Thermodynamics | 1990 |
Phylogeny of immune recognition: antigen processing/presentation in channel catfish immune responses to hemocyanins.
Topics: Ammonium Chloride; Animals; Antibody Formation; Antigen-Presenting Cells; Antigens; B-Lymphocytes; Chloroquine; Fixatives; Hemocyanins; Ictaluridae; In Vitro Techniques; Leupeptins; Lymphocyte Activation; Monensin; Monocytes; Phenylmethylsulfonyl Fluoride | 1990 |
Expression and processing of procholecystokinin in a rat medullary thyroid carcinoma cell line.
Topics: Animals; Carcinoma; Chloroquine; Cholecystokinin; Chromatography, Gel; Colchicine; Dexamethasone; Gene Expression; Glycine; Monensin; Peptide Fragments; Protein Precursors; Protein Processing, Post-Translational; Rats; Sincalide; Sulfates; Thyroid Neoplasms; Tumor Cells, Cultured | 1990 |
Inhibition of catabolism of radiolabeled antibodies by tumor cells using lysosomotropic amines and carboxylic ionophores.
Topics: Acid Phosphatase; Amantadine; Ammonium Chloride; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Chloroquine; Chromatography, High Pressure Liquid; Humans; Iodine Radioisotopes; Lysosomes; Mice; Monensin; Nigericin; Temperature; Tumor Cells, Cultured; Verapamil | 1990 |
Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.
Topics: Chloroquine; Cobalt; Deferoxamine; Heptanoates; Humans; In Vitro Techniques; Luciferases; Monensin; Phagocytosis; Polylysine; Porphobilinogen Synthase; Receptors, Transferrin; Transferrin; Transformation, Genetic; Tumor Cells, Cultured | 1990 |
Intracellular regulation of lipoprotein lipase in human monocyte-derived macrophages.
Topics: Cell Differentiation; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Humans; In Vitro Techniques; Lipoprotein Lipase; Macrophages; Monensin; Monocytes; Secretory Rate; Tunicamycin | 1990 |
Uptake and intracellular processing of targeted and nontargeted liposomes by rat Kupffer cells in vivo and in vitro.
Topics: alpha-Fetoproteins; Animals; Asialoglycoproteins; Cells, Cultured; Chloroquine; Colchicine; Cytochalasins; Endocytosis; Fetuins; Hexosamines; Kupffer Cells; Lactosylceramides; Liposomes; Lysosomes; Membrane Lipids; Metabolic Clearance Rate; Monensin; Phosphatidylcholines; Rats; Sphingomyelins; Structure-Activity Relationship; Trifluoperazine | 1985 |
A nonendocytotic mechanism for the selective uptake of high density lipoprotein-associated cholesterol esters.
Topics: Adrenal Cortex Neoplasms; alpha-Fetoproteins; Animals; Apolipoprotein A-I; Apolipoproteins A; Asialoglycoproteins; Azides; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Colchicine; Fetuins; Fibroblasts; Heparin; Humans; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Liver Neoplasms; Mice; Monensin; Pinocytosis; Rats; Sodium Azide | 1987 |
Zymogen granule acidity is not required for stimulated pancreatic protein secretion.
Topics: Amylases; Animals; Chloroquine; Cytoplasmic Granules; Enzyme Precursors; Exocytosis; Hydrogen-Ion Concentration; Male; Methylamines; Mice; Microscopy, Electron; Monensin; Pancreas; Secretory Rate; Sincalide | 1987 |
Intracellular degradation of unassembled asialoglycoprotein receptor subunits: a pre-Golgi, nonlysosomal endoproteolytic cleavage.
Topics: Acetylglucosaminidase; Animals; Asialoglycoprotein Receptor; Cell Line; Chloroquine; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Fluorescent Antibody Technique; Golgi Apparatus; Half-Life; Leupeptins; Lysosomes; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Microscopy, Fluorescence; Molecular Weight; Monensin; Receptors, Immunologic; Temperature | 1989 |
Competition for antigen presentation in living cells involves exchange of peptides bound by class II MHC molecules.
Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Cell Line; Chloroquine; Fixatives; Glutaral; Histocompatibility Antigens Class II; Hydrogen-Ion Concentration; Interleukin-2; Kinetics; Methylamines; Mice; Monensin; Muramidase; Peptides; Protein Binding; T-Lymphocytes; Temperature | 1989 |
Binding and intracellular degradation of atrial natriuretic factor by cultured vascular smooth muscle cells.
Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Chloroquine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Monensin; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains | 1989 |
Cytolysis by Ca-permeable transmembrane channels. Pore formation causes extensive DNA degradation and cell lysis.
Topics: Aminoquinolines; Ammonium Chloride; Bacterial Toxins; Calcium; Calcium Channels; Cell Line; Cell Membrane Permeability; Cell Survival; Chloroquine; Chromium Radioisotopes; DNA; Egtazic Acid; Hemolysin Proteins; Humans; Idoxuridine; Interleukin-2; Killer Cells, Natural; Membrane Glycoproteins; Membrane Proteins; Monensin; Neurotoxins; Perforin; Pore Forming Cytotoxic Proteins; Staphylococcus; Tumor Necrosis Factor-alpha | 1989 |
A growth hormone-vesicular stomatitis virus G hybrid protein is rapidly degraded in lysosomes following transport to the cell surface.
Topics: Animals; Cells, Cultured; Chloroquine; Cricetinae; Endocytosis; Growth Hormone; Kidney; Leupeptins; Lysosomes; Membrane Proteins; Monensin; Vesicular stomatitis Indiana virus; Viral Proteins | 1989 |
Membrane-coating granules are acidic organelles which possess proton pumps.
Topics: Animals; Cells, Cultured; Chloroquine; Culture Media; Hydrogen-Ion Concentration; Intracellular Membranes; Microscopy, Electron; Monensin; Organelles; Protons; Skin; Swine | 1989 |
Differential effects of leupeptin, monensin and colchicine on ligand degradation mediated by the two asialoglycoprotein receptor pathways in isolated rat hepatocytes.
Topics: Animals; Asialoglycoproteins; Cells, Cultured; Chloroquine; Colchicine; Dose-Response Relationship, Drug; Galactose; Leupeptins; Liver; Male; Monensin; Oligopeptides; Orosomucoid; Rats; Rats, Inbred Strains; Receptors, Cell Surface | 1989 |
Glycolysis in P-glycoprotein-overexpressing human tumor cell lines. Effects of resistance-modifying agents.
Topics: Adenosine Triphosphate; Amiloride; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Proteins; Chloroquine; Cytochalasin B; Drug Resistance; Energy Metabolism; Glutathione Transferase; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Membrane Glycoproteins; Monensin; Nigericin; Oxygen Consumption; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil | 1989 |
Loss of surface galactosyl receptor activity on isolated rat hepatocytes induced by monensin or chloroquine requires receptor internalization via a clathrin coated pit pathway.
Topics: Animals; Chloroquine; Coated Pits, Cell-Membrane; Endocytosis; Endosomes; Galactose; Liver; Male; Monensin; Osmolar Concentration; Rats; Rats, Inbred Strains; Receptors, Cell Surface | 1989 |
Antigen processing by isolated rat intestinal villus enterocytes.
Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Cell Separation; Chloroquine; Intestinal Mucosa; Leupeptins; Lysosomes; Microvilli; Monensin; Ovalbumin; Rats | 1989 |
Relations between resistance to chloroquine and acidification of endocytic vesicle of Plasmodium berghei.
Topics: Animals; Chloroquine; Dinitrobenzenes; Drug Resistance; Endocytosis; Hydrogen-Ion Concentration; Immunohistochemistry; Magnetic Resonance Spectroscopy; Microscopy, Electron; Molecular Structure; Monensin; Plasmodium berghei | 1989 |
The influence of pH on the vesicular traffic to the surface of the polarized epithelial cell, MDCK.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Dogs; Epithelium; Exocytosis; Hydrogen-Ion Concentration; Kidney; Membrane Glycoproteins; Monensin; Muramidase | 1989 |
Monensin and chloroquine inhibit transfer to lysosomes of endocytosed macromolecules in cultured mouse peritoneal macrophages.
Topics: Animals; Biological Transport; Cells, Cultured; Chloroquine; Endocytosis; Ferritins; Histocytochemistry; Lysosomes; Macrophages; Male; Mice; Microscopy, Electron; Monensin; Peritoneum; Time Factors | 1989 |
Requirements for histoplasmin presentation by accessory cells to a Histoplasma capsulatum-reactive T-cell line.
Topics: Ammonium Chloride; Animals; Antibodies, Monoclonal; Antigen-Presenting Cells; Antigens, Fungal; Azides; Cell Line; Cerulenin; Chloroquine; Deoxyglucose; Formaldehyde; Histoplasma; Histoplasmin; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Monensin; Phospholipases A; Phospholipases A2; Polymers; Protease Inhibitors; Sodium Azide; T-Lymphocytes; Temperature | 1989 |
Time-dependent cleavage of a high-mannose form of Ii to p25 in an intracellular compartment.
Topics: Chemical Phenomena; Chemistry; Chloroquine; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Histocompatibility Antigens Class II; Intracellular Membranes; Mannose; Molecular Weight; Monensin; Precipitin Tests; Time Factors | 1989 |
Secretion of alpha-tocopherol from cultured rat hepatocytes.
Topics: Animals; Cells, Cultured; Chloroquine; Colchicine; Eicosapentaenoic Acid; Kinetics; Liver; Male; Monensin; Oleic Acid; Oleic Acids; Perfusion; Rats; Rats, Inbred Strains; Vitamin E | 1987 |
Internalization and recycling of receptor-bound gonadotropin-releasing hormone agonist in pituitary gonadotropes.
Topics: Affinity Labels; Animals; Azides; Buserelin; Chloroquine; Gonadotropin-Releasing Hormone; Iodine Radioisotopes; Isotope Labeling; Molecular Weight; Monensin; Photochemistry; Pituitary Gland; Receptors, LHRH; Trypsin | 1987 |
Biosynthesis and processing of lactoferrin in bone marrow cells, a comparison with processing of myeloperoxidase.
Topics: Ammonium Chloride; Biological Transport; Bone Marrow; Cell Compartmentation; Chloroquine; Cytoplasmic Granules; Glycosylation; Hexosaminidases; Humans; In Vitro Techniques; Lactoferrin; Lactoglobulins; Lysosomes; Molecular Weight; Monensin; Peroxidase; Protein Processing, Post-Translational | 1988 |
The effects of monensin on inhibition of steroidogenesis and disruption of the Golgi complex in adrenal cells are both reversible!
Topics: 2,4-Dinitrophenol; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Chloroquine; Chromatography, High Pressure Liquid; Dinitrophenols; Golgi Apparatus; Mice; Microscopy, Electron; Monensin | 1987 |
Functional and biochemical parameters of peptide antigen presentation.
Topics: alpha-MSH; Animals; Antigen-Presenting Cells; Cell Membrane; Chloroquine; Glutaral; Histocompatibility Antigens Class II; Interleukin-2; Lymphocyte Activation; Methylamines; Mice; Molecular Weight; Monensin; Peptides; T-Lymphocytes | 1988 |
Evidence for two independent pathways of insulin-receptor internalization in hepatocytes and hepatoma cells.
Topics: 2,4-Dinitrophenol; Animals; Biological Transport; Biotransformation; Carcinoma, Hepatocellular; Cells, Cultured; Chloroquine; Coated Pits, Cell-Membrane; Dinitrophenols; Humans; Insulin; Leupeptins; Liver; Liver Neoplasms; Monensin; Osmolar Concentration; Potassium; Rats; Receptor, Insulin; Tumor Cells, Cultured | 1988 |
Interactions of cholera toxin with isolated hepatocytes. Effects of low pH, chloroquine and monensin on toxin internalization, processing and action.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Chloroquine; Cholera Toxin; Cyclic AMP; Enzyme Activation; Hydrogen-Ion Concentration; Immune Sera; In Vitro Techniques; Liver; Male; Monensin; Peptides; Rats; Rats, Inbred Strains | 1988 |
Down-regulation of calcitonin receptors in T47D cells by internalization of calcitonin-receptor complexes.
Topics: Chloroquine; Female; Humans; Monensin; Receptors, Calcitonin; Receptors, Cell Surface; Tumor Cells, Cultured | 1988 |
Internalization and cycling of nerve growth factor in PC12 cells: interconversion of type II (fast) and type I (slow) nerve growth factor receptors.
Topics: Animals; Arsenicals; Chloroquine; Digitonin; Endocytosis; Monensin; Nerve Growth Factors; Pheochromocytoma; Rats; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Tumor Cells, Cultured | 1988 |
Entry of poliovirus type 1 and Mouse Elberfeld (ME) virus into HEp-2 cells: receptor-mediated endocytosis and endosomal or lysosomal uncoating.
Topics: Ammonium Chloride; Cell Line; Chloroquine; Endocytosis; Endosomes; Hydrogen-Ion Concentration; Lysosomes; Monensin; Picornaviridae; Poliovirus; RNA, Viral; Virus Replication | 1985 |
Internalization of transforming growth factor-beta and its receptor in BALB/c 3T3 fibroblasts.
Topics: Animals; Cell Line; Cell Membrane; Chloroquine; Fibroblasts; Growth Substances; Hydrogen-Ion Concentration; Lysosomes; Mice; Monensin; Peptides; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Transforming Growth Factors | 1986 |
Release of the variant surface glycoprotein during differentiation of bloodstream to procyclic forms of Trypanosoma brucei.
Topics: Ammonium Chloride; Animals; Antigens, Protozoan; Cell Membrane; Chloroquine; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Membrane Proteins; Monensin; Photofluorography; Precipitin Tests; Tosyllysine Chloromethyl Ketone; Trypanosoma brucei brucei | 1989 |
Early events in arenavirus replication are sensitive to lysosomotropic compounds.
Topics: Adsorption; Amantadine; Ammonium Chloride; Antiviral Agents; Arenaviridae; Chloroquine; Lassa virus; Monensin; Virus Replication | 1989 |
Inhibition by leupeptin and antipain of the intracellular proteolysis of Ii.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, B-Lymphocyte; Antipain; Cells, Cultured; Chloroquine; Electrophoresis, Gel, Two-Dimensional; Histocompatibility Antigens Class II; Hydrogen-Ion Concentration; Leupeptins; Monensin; Oligopeptides; Peptide Fragments | 1989 |
Receptor-mediated endocytosis of immunoglobulin-coated colloidal gold particles in cultured mouse peritoneal macrophages. Chloroquine and monensin inhibit transfer of the ligand from endocytic vesicles to lysosomes.
Topics: Animals; Biological Transport, Active; Cells, Cultured; Chloroquine; Endocytosis; Furans; Gold; Horseradish Peroxidase; Immunoglobulin G; Lysosomes; Macrophages; Male; Mice; Mice, Inbred Strains; Monensin; Peritoneal Cavity; Receptors, IgG; Receptors, Immunologic | 1985 |
Comparative studies on insulin-like growth factor II and insulin processing by vascular endothelial cells.
Topics: Animals; Aorta; Biological Transport; Cattle; Cells, Cultured; Chloroquine; Endothelium; Insulin; Insulin-Like Growth Factor II; Kinetics; Leupeptins; Models, Biological; Monensin; Receptor, Insulin; Receptors, Somatomedin; Somatomedins | 1986 |
Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes?
Topics: Ammonium Chloride; Carrier Proteins; Cathepsin D; Cell Membrane; Cells, Cultured; Chloroquine; Cycloheximide; Humans; Intracellular Membranes; Lysosomes; Mannosephosphates; Monensin; Receptor, IGF Type 2 | 1987 |
Down-regulation of parathyroid hormone (PTH) receptors in cultured bone cells is associated with agonist-specific intracellular processing of PTH-receptor complexes.
Topics: Animals; Arsenicals; Bone and Bones; Cell Membrane; Cells, Cultured; Chick Embryo; Chloroquine; Cyclic AMP; Drug Synergism; Monensin; Parathyroid Hormone; Peptide Fragments; Receptors, Cell Surface; Receptors, Parathyroid Hormone | 1986 |
Deletion of clustered O-linked carbohydrates does not impair function of low density lipoprotein receptor in transfected fibroblasts.
Topics: Amino Acid Sequence; Animals; Carbohydrates; Cell Line; Chloroquine; Chromatography, Affinity; Chromatography, Paper; Cricetinae; Cricetulus; Cycloheximide; DNA; Female; Fibroblasts; Glucosamine; Humans; Molecular Weight; Monensin; Ovary; Receptors, LDL; Simian virus 40; Transfection; Tunicamycin | 1986 |
The processing and intracellular transport of myeloperoxidase. Modulation by lysosomotropic agents and monensin.
Topics: Ammonium Chloride; Biological Transport, Active; Body Fluids; Cell Line; Chloroquine; Furans; Humans; Intracellular Fluid; Lysosomes; Molecular Weight; Monensin; Oligosaccharides; Peroxidase; Phosphorylation | 1986 |
Processing of a newly identified intermediate of human myeloperoxidase in isolated granules occurs at neutral pH.
Topics: Ammonium Chloride; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Chloroquine; Cytoplasmic Granules; Hexosaminidases; Humans; Hydrogen-Ion Concentration; Ionophores; Leukemia, Myeloid, Acute; Molecular Weight; Monensin; Peroxidase; Protein Processing, Post-Translational | 1986 |
Effect of lysosomotropic compounds on early events in foot-and-mouth disease virus replication.
Topics: Ammonium Chloride; Animals; Aphthovirus; Cattle; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Lysosomes; Monensin; Species Specificity; Virus Replication | 1987 |
Internalization of human T lymphocyte receptors.
Topics: Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Chloroquine; Cytoplasm; Deltaretrovirus; Endocytosis; Flow Cytometry; Fluorescent Antibody Technique; Humans; Inclusion Bodies; Microscopy, Electron; Monensin; Receptors, Antigen, T-Cell; Receptors, Virus; T-Lymphocytes; T-Lymphocytes, Helper-Inducer | 1987 |
On the effects of weak bases and monensin on sorting and processing of lysosomal enzymes in human cells.
Topics: Ammonium Chloride; Carcinoma, Hepatocellular; Cathepsin D; Cell Line; Chloroquine; Fibroblasts; Humans; Kinetics; Liver Neoplasms; Lysosomes; Monensin; Primaquine; Protein Processing, Post-Translational; Skin | 1987 |
Cycling of the integral membrane glycoprotein, LEP100, between plasma membrane and lysosomes: kinetic and morphological analysis.
Topics: Animals; Avian Proteins; Cell Membrane; Chickens; Chloroquine; Clathrin; Coated Pits, Cell-Membrane; Fibroblasts; Kinetics; Lysosomes; Membrane Glycoproteins; Monensin | 1987 |
Internalization and degradation of human recombinant interferon-gamma in the human histiocytic lymphoma cell line, U937: relationship to Fc receptor enhancement and antiproliferation.
Topics: Cell Line; Chloroquine; Colchicine; Cytochalasin B; Endocytosis; Humans; In Vitro Techniques; Interferon-gamma; Monensin; Monocytes; Receptors, Fc; Recombinant Proteins; Time Factors | 1988 |
Biosynthesis of lysosomal cathepsins B and H in cultured rat hepatocytes.
Topics: Alkaloids; Ammonium Chloride; Animals; Cathepsin B; Cathepsin H; Cathepsins; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Kinetics; Liver; Lysosomes; Male; Monensin; Rats; Rats, Inbred Strains; Swainsonine; Tunicamycin | 1988 |
Cellular internalisation of Clostridium difficile toxin A.
Topics: Animals; Bacterial Toxins; Benzyl Compounds; Cell Line; Chloroquine; Clostridium; Enterotoxins; Humans; Kinetics; Monensin; Potassium Chloride | 1987 |
Internalization and cellular processing of cholecystokinin in rat pancreatic acinar cells.
Topics: Animals; Biological Transport; Cell Membrane; Chloroquine; Dithiothreitol; In Vitro Techniques; Kinetics; Male; Monensin; Pancreas; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide | 1988 |
Aminoterminal propeptide of type III procollagen is cleared from the circulation by receptor-mediated endocytosis in liver endothelial cells.
Topics: Animals; Cells, Cultured; Chloroquine; Endocytosis; Endothelium; Kinetics; Leupeptins; Liver; Monensin; Peptide Fragments; Procollagen; Rats | 1988 |
Mediation of reduction of spontaneous and experimental pulmonary metastases by ricin A-chain immunotoxin 45-2D9-RTA with potentiation by systemic monensin in mice.
Topics: Ammonium Chloride; Animals; Antigens, Neoplasm; Chloroquine; Dimethyl Sulfoxide; Drug Synergism; Female; Immunotoxins; Lung Neoplasms; Mice; Mice, Inbred BALB C; Monensin; Ricin | 1988 |
Rapid constitutive internalization and externalization of epidermal growth factor receptors in isolated rat hepatocytes. Monensin inhibits receptor externalization and reduces the capacity for continued endocytosis of epidermal growth factor.
Topics: Animals; Cell Membrane; Chloroquine; Cycloheximide; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Kinetics; Liver; Male; Monensin; Rats; Rats, Inbred Strains; Tunicamycin | 1988 |
Processing requirements for T cell activation by Mycoplasma arthritidis-derived mitogen.
Topics: Ammonium Chloride; Antigen-Presenting Cells; Chloroquine; Formaldehyde; Leupeptins; Lymphocyte Activation; Lysosomes; Macrophages; Mitogens; Monensin; Mycoplasma; Polymers; T-Lymphocytes | 1988 |
Intracellular insulin-receptor dissociation and segregation in a rat fibroblast cell line transfected with a human insulin receptor gene.
Topics: Animals; Cell Line; Chloroquine; Fibroblasts; Gene Amplification; Humans; Insulin; Monensin; Octoxynol; Polyethylene Glycols; Rats; Receptor, Insulin; Solubility; Time Factors; Transfection | 1988 |
Role for intracellular proteases in the processing and transport of class II HLA antigens.
Topics: Biological Transport; Chloroquine; HLA-D Antigens; Humans; Leupeptins; Molecular Weight; Monensin; Peptide Hydrolases; Protein Processing, Post-Translational | 1988 |
Uncoupling between the insulin-receptor cycle and the cellular degradation of the hormone in cultured foetal hepatocytes. Effect of drugs and temperature that inhibit insulin degradation.
Topics: Animals; Bacitracin; Cells, Cultured; Chloroquine; Insulin; Liver; Monensin; Rats; Rats, Inbred Strains; Receptor, Insulin; Temperature; Vinblastine | 1987 |
Post-translational processing of the murine third component of complement.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Complement C3; Glycosylation; Humans; Macrophages; Mice; Monensin; Protein Precursors; Protein Processing, Post-Translational; Valinomycin | 1988 |
Chloroquine and monensin inhibit induction of DNA synthesis in rat arterial smooth muscle cells stimulated with platelet-derived growth factor.
Topics: Animals; Cells, Cultured; Chloroquine; DNA; Hydrogen-Ion Concentration; Leucine; Male; Monensin; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Inbred Strains; Time Factors; Tritium; Uridine | 1988 |
Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles.
Topics: Ammonium Chloride; Animals; Binding, Competitive; Carrier Proteins; Cell Line; Cell Membrane; Chloroquine; Chromatography, Gel; Chromatography, High Pressure Liquid; Cytoplasm; Epithelium; Folate Receptors, GPI-Anchored; Folic Acid; Kinetics; Monensin; Receptors, Cell Surface; Tetrahydrofolates; Tritium | 1988 |
Interaction between monensin and lysosomotropic amines in the regulation of the processing of epidermal growth factor by BALB/c 3T3 cells.
Topics: Animals; Chloroquine; Clone Cells; Culture Media; Epidermal Growth Factor; Methylamines; Mice; Monensin | 1987 |
Electron microscopic evidence for stimulation of melanosomal maturation by lysosomotropic agents and monensin in cultured B16 mouse melanoma cells.
Topics: Ammonium Chloride; Animals; Cell Division; Cell Line; Chloroquine; Cytoplasmic Granules; Lysosomes; Melanocytes; Melanoma, Experimental; Mice; Microscopy, Electron; Monensin | 1987 |
Recycling of photoaffinity-labeled insulin receptors in rat adipocytes. Dissociation of insulin-receptor complexes is not required for receptor recycling.
Topics: Adipose Tissue; Affinity Labels; Animals; Azides; Chloroquine; Electrophoresis, Polyacrylamide Gel; Insulin; Iodine Radioisotopes; Kinetics; Male; Molecular Weight; Monensin; Peptide Fragments; Photolysis; Rats; Rats, Inbred Strains; Receptor, Insulin; Thermodynamics; Tromethamine; Trypsin | 1986 |
Processing and release of insulin and insulin-like growth factor I by macro- and microvascular endothelial cells.
Topics: Animals; Aorta; Capillaries; Cattle; Chloroquine; Insulin; Male; Microcirculation; Microscopy, Electron; Monensin; Rats; Receptor, Insulin; Somatomedins; Temperature; Time Factors | 1986 |
Potentiation of specific association of insulin with HepG2 cells by phorbol esters.
Topics: Animals; Cell Line; Chloroquine; Drug Synergism; Humans; Insulin; Liver Neoplasms, Experimental; Monensin; Phorbol Esters; Phospholipases; Protein Binding; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of very-low-density lipoprotein secretion by chloroquine, verapamil and monensin takes place in the Golgi complex.
Topics: Animals; Chloroquine; Golgi Apparatus; Kinetics; Lipoproteins, VLDL; Liver; Male; Mathematics; Microscopy, Electron; Models, Biological; Monensin; Rats; Verapamil | 1987 |
Cerulenin is a potent inhibitor of antigen processing by antigen-presenting cells.
Topics: Ammonium Chloride; Animals; Antifungal Agents; Antigen-Presenting Cells; Antigens; Cell Line; Cerulenin; Chloroquine; Depression, Chemical; Lymphocyte Activation; Mice; Monensin | 1987 |
Cytotoxic activity of stimulated mouse macrophages exposed to various inhibitors.
Topics: Animals; Carbon Radioisotopes; Cell Line; Chloroquine; Colchicine; Cytotoxicity, Immunologic; Lysosomes; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Monensin; Neoplasms, Experimental; Peritoneal Cavity; Zymosan | 1986 |
Monensin stimulation of arylsulfatase B activity in human chondrocytes.
Topics: Aged; Ammonium Chloride; Cartilage, Articular; Cell Count; Cells, Cultured; Chloroquine; Chondro-4-Sulfatase; Dose-Response Relationship, Drug; Female; Furans; Humans; Lysosomes; Male; Middle Aged; Monensin; Osteoarthritis; Sulfatases | 1986 |
Effects of monensin on insulin processing in adipocytes. Evidence that the internalized insulin-receptor complex has some physiological activities.
Topics: Adenosine Triphosphate; Adipose Tissue; Animals; Carrier Proteins; Chloroquine; Furans; Insulin; Male; Monensin; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Receptor, Insulin | 1985 |
Bone marrow pre-B lymphocytes synthesize immunoglobulin mu chains of membrane type with different properties and intracellular pathways.
Topics: Animals; B-Lymphocytes; Bone Marrow; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Compartmentation; Cells, Cultured; Chloroquine; Immunoglobulin Heavy Chains; Immunoglobulin mu-Chains; Membrane Proteins; Mice; Mice, Inbred Strains; Monensin; Peptide Hydrolases; Protein Processing, Post-Translational; RNA, Messenger | 1985 |
Subcellular characterization of the endocytosis of small oligomers of mouse immunoglobulin G in murine macrophages.
Topics: Animals; Antigen-Antibody Complex; Asialoglycoproteins; Centrifugation, Density Gradient; Chloroquine; Endocytosis; Immunoglobulin G; Kinetics; Lysosomes; Macromolecular Substances; Macrophages; Male; Mice; Mice, Inbred C3H; Monensin; Subcellular Fractions | 1986 |
Effect of monensin on myoblast fusion.
Topics: Ammonium Chloride; Animals; Cell Fusion; Chick Embryo; Chloroquine; Furans; Mannose; Monensin; Muscles; Pronase | 1985 |
Complete inhibition of transferrin recycling by monensin in K562 cells.
Topics: Cell Line; Chloroquine; Fluorescent Antibody Technique; Furans; Humans; Kinetics; Leukemia, Myeloid, Acute; Microscopy, Electron; Monensin; Receptors, Cell Surface; Receptors, Transferrin; Transferrin | 1984 |
Diacytosis of 125I-asialoorosomucoid by rat hepatocytes. A non-lysosomal pathway insensitive to inhibition by inhibitors of ligand degradation.
Topics: Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Cells, Cultured; Chloroquine; Colchicine; Cold Temperature; Endocytosis; Endosomes; Exocytosis; Kinetics; Leupeptins; Liver; Lysosomes; Monensin; Rats; Receptors, Immunologic | 1984 |
Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.
Topics: alpha-Macroglobulins; Ammonia; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Chloroquine; Endocytosis; Epidermal Growth Factor; Fibroblasts; Hydrogen-Ion Concentration; Ionophores; Methylamines; Mice; Monensin; Organoids | 1982 |
Monensin inhibits intracellular dissociation of asialoglycoproteins from their receptor.
Topics: Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Cells, Cultured; Centrifugation, Density Gradient; Chloroquine; Endocytosis; Furans; Glycoproteins; Liver; Lysosomes; Monensin; Rats; Receptors, Cell Surface | 1983 |
Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts.
Topics: Cells, Cultured; Chloroquine; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Humans; Kinetics; Lysosomes; Methylamines; Monensin; Receptors, Cell Surface | 1984 |
Role of a low-pH environment in adenovirus enhancement of the toxicity of a Pseudomonas exotoxin-epidermal growth factor conjugate.
Topics: Adenoviruses, Human; Amines; Ammonium Chloride; Carcinoma; Cell Line; Chloroquine; Drug Synergism; Epidermal Growth Factor; Exotoxins; Humans; Hydrogen-Ion Concentration; Kinetics; Methylamines; Monensin; Mouth Neoplasms; Protein Biosynthesis; Pseudomonas; Receptors, Virus | 1984 |
Antigen conformation determines processing requirements for T-cell activation.
Topics: Ammonium Chloride; Animals; Antigens; Chloroquine; Clone Cells; Leupeptins; Lymphocyte Activation; Lysosomes; Mice; Monensin; Myoglobin; Peptide Fragments; Protein Conformation; Protein Denaturation; Structure-Activity Relationship; T-Lymphocytes | 1984 |
Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine.
Topics: Ammonium Chloride; Animals; Chloroquine; Endocytosis; Erythrocytes; Humans; Hydrogen-Ion Concentration; Kinetics; Malaria; Methylamines; Monensin; Plasmodium falciparum | 1984 |
Mechanism of autodegradation of cell-surface macromolecules shed by human melanoma cells.
Topics: Ammonium Chloride; Biological Transport; Cadaverine; Cell Line; Chloroquine; Coated Pits, Cell-Membrane; Colchicine; Cytochalasin B; Endocytosis; Humans; Leupeptins; Lysosomes; Melanoma; Membrane Proteins; Monensin; Neoplasm Proteins; Time Factors; Tunicamycin | 1984 |
Stimulation of the release of lysosomal and nonlysosomal granular enzymes from macrophages treated with monensin.
Topics: Acid Phosphatase; alpha-Glucosidases; Ammonium Chloride; Animals; beta-Galactosidase; beta-Glucosidase; Chloroquine; Furans; Galactosyltransferases; Glucuronidase; Golgi Apparatus; Hexosaminidases; Hydrogen-Ion Concentration; Lysosomes; Macrophages; Mice; Monensin; Solubility | 1984 |
Degradation of surface-labeled hepatoma membrane polypeptides: effect of inhibitors.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Iodine Radioisotopes; Liver Neoplasms, Experimental; Lysosomes; Membrane Proteins; Monensin; Neoplasm Proteins; Peptides; Protease Inhibitors; Rats; Temperature | 1984 |
Anti-immunoglobulin-induced proliferation of B cells. Parallelism in the inhibition by chloroquine, monensin and immunoglobulin.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Chloroquine; Furans; Immunoglobulin G; Kinetics; Lymphocyte Activation; Monensin; Puromycin; Rabbits | 1983 |
Subcellular sites of processing of precursors to neurosecretory peptides in the bag cells of Aplysia: inferences from the effects of monensin, FCCP, and chloroquine.
Topics: Animals; Aplysia; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Chloroquine; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Furans; Golgi Apparatus; Invertebrate Hormones; Microscopy, Electron; Monensin; Neurosecretory Systems; Nitriles; Peptides; Subcellular Fractions | 1984 |
Temperature-dependent internalization of virus glycoproteins in cells infected with a mutant of Semliki Forest virus.
Topics: Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Chloroquine; Fluorescent Antibody Technique; Immunoglobulin Fab Fragments; Kinetics; Monensin; Mutation; Semliki forest virus; Temperature; Viral Proteins | 1982 |
Requirements for the processing of antigens by antigen-presenting B cells. I. Functional comparison of B cell tumors and macrophages.
Topics: Animals; B-Lymphocytes; Cell Membrane; Chloroquine; Interleukin-2; Kinetics; Lymphocyte Cooperation; Macrophages; Mice; Monensin; Protein Conformation; Receptors, Antigen, B-Cell | 1982 |
Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells.
Topics: Amino Acid Sequence; Ammonium Chloride; Animals; Arsenicals; Cell Line, Transformed; Chloroquine; Colchicine; Endocytosis; Epithelium; Hypertonic Solutions; Immune Sera; Immunohistochemistry; Kinetics; Leupeptins; Microscopy, Fluorescence; Molecular Sequence Data; Monensin; Peptides; Rats; Receptors, Neurokinin-1; Recombinant Proteins; Substance P; Time Factors; Transfection | 1994 |
Iron acquired from transferrin by K562 cells is delivered into a cytoplasmic pool of chelatable iron(II).
Topics: 2,2'-Dipyridyl; Ammonium Chloride; Azides; Biological Transport; Cell Line; Chloroquine; Cytoplasm; Endocytosis; Fluoresceins; Humans; Iron; Iron Chelating Agents; Kinetics; Leukemia, Erythroblastic, Acute; Monensin; Receptors, Transferrin; Transferrin; Tumor Cells, Cultured | 1995 |
Intracellular degradation of type I collagen and fibronectin in human lung fibroblasts: evidence against degradation in pre-lysosomal compartments.
Topics: 2,2'-Dipyridyl; Biological Transport; Brefeldin A; Canavanine; Cell Line; Cell Membrane Permeability; Chloroquine; Collagen; Cyclopentanes; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Fibroblasts; Fibronectins; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydroxybenzoates; Lung; Monensin; Organelles; Protein Folding; Protein Synthesis Inhibitors | 1995 |
Double immunofluorescent staining of alpha 2,6 sialyltransferase and beta 1,4 galactosyltransferase in monensin-treated cells: evidence for different Golgi compartments?
Topics: Antibodies, Monoclonal; Base Sequence; beta-D-Galactoside alpha 2-6-Sialyltransferase; Brefeldin A; Cell Compartmentation; Chloroquine; Cyclopentanes; Fluorescent Antibody Technique; Golgi Apparatus; HeLa Cells; Humans; Molecular Sequence Data; Monensin; N-Acetyllactosamine Synthase; Nocodazole; Sialyltransferases; Staining and Labeling; Tumor Cells, Cultured | 1993 |
Delivery and cytotoxicity of RS-1541 in St-4 human gastric cancer cells in vitro by the low-density-lipoprotein pathway.
Topics: Antibiotics, Antineoplastic; Chloroquine; Drug Carriers; Drug Interactions; Humans; Lactones; Lipoproteins, LDL; Monensin; Stomach Neoplasms; Tumor Cells, Cultured | 1995 |
Processing of complex antigens and simple hapten-like molecules by epidermal Langerhans cells.
Topics: Animals; Antigen Presentation; Chloroquine; Cycloheximide; Cytochalasin B; Dermatitis, Contact; Female; Langerhans Cells; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Monensin; Ovalbumin; Skin; Trinitrobenzenes | 1995 |
Calcium dependent cellular uptake of a c-myc antisense oligonucleotide.
Topics: Animals; Arsenicals; Base Sequence; Biological Transport; Calcium; Cell Line; Chloroquine; Deoxyglucose; Genes, myc; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Macrophages; Molecular Sequence Data; Monensin; Oligonucleotides, Antisense; Proto-Oncogene Mas; Trypsin; Tumor Cells, Cultured | 1994 |
Monensin and brefeldin A inhibit high density lipoprotein-mediated cholesterol efflux from cholesterol-enriched cells. Implications for intracellular cholesterol transport.
Topics: Ammonium Chloride; Animals; Aorta, Abdominal; Biological Transport; Brefeldin A; Cells, Cultured; Chloroquine; Cholesterol; Cyclopentanes; Dose-Response Relationship, Drug; Fibroblasts; Humans; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Male; Models, Biological; Monensin; Muscle, Smooth, Vascular; Nigericin; Protein Synthesis Inhibitors; Skin; Sterols; Swine | 1995 |
Involvement of the vacuolar H(+)-ATPase in animal virus entry.
Topics: Amantadine; Animals; Anti-Bacterial Agents; Cadaverine; Cell Line; Chloroquine; Cricetinae; DNA Viruses; Electrophoresis, Polyacrylamide Gel; Endocytosis; HeLa Cells; Humans; Kidney; Macrolides; Methionine; Monensin; Proton-Translocating ATPases; Receptors, Virus; RNA Viruses; Semliki forest virus; Vacuoles; Viral Proteins | 1994 |
Selective uptake of high-density lipoprotein-associated cholesteryl esters and high-density lipoprotein particle uptake by human monocyte-macrophages.
Topics: Apolipoprotein A-I; Cells, Cultured; Chloroquine; Cholesterol Esters; Endocytosis; Humans; Hydrolysis; Lipoproteins, HDL; Lipoproteins, HDL3; Macrophages; Monensin; Monocytes | 1994 |
Endocytosis of a cytotoxic human high density lipoprotein results in disruption of acidic intracellular vesicles and subsequent killing of African trypanosomes.
Topics: Acids; Ammonium Chloride; Animals; Chloroquine; Dose-Response Relationship, Drug; Endocytosis; Flagella; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Intracellular Membranes; Leupeptins; Lipoproteins, HDL; Microscopy, Immunoelectron; Models, Biological; Monensin; Organelles; Protein Binding; Trypanosoma brucei brucei | 1994 |
Interaction of a cholera toxin derivative containing a reduced number of receptor binding sites with intact cells in culture.
Topics: Animals; Binding Sites; Cells, Cultured; Chloroquine; Cholera Toxin; Cyclic AMP; Fibroblasts; G(M1) Ganglioside; HeLa Cells; Humans; Monensin; Receptors, Cell Surface; Temperature; Vero Cells | 1994 |
Intracellular proteolysis of poliovirus eclipse particles is abortive.
Topics: Amodiaquine; Biological Transport; Chloroquine; Chlorpromazine; HeLa Cells; Humans; Hydrogen-Ion Concentration; Lysosomes; Monensin; Poliovirus; Viral Proteins; Virion | 1994 |
Inhibitors of endocytosis, endosome fusion, and lysosomal processing inhibit the intracellular proteolysis of the amyloid precursor protein.
Topics: Adenine; Amyloid beta-Protein Precursor; Animals; Chloroquine; Colchicine; Cytochalasin B; Endocytosis; Lysosomes; Monensin; Organelles; PC12 Cells; Rats | 1993 |
Effect of cell volume on Acridine Orange fluorescence in hepatocytes.
Topics: Acridine Orange; Ammonia; Animals; Barium; Cell Compartmentation; Cell Size; Chloroquine; Endopeptidases; Fluorescence; Glutamine; Hydrogen-Ion Concentration; Liver; Monensin; Organelles; Osmolar Concentration | 1993 |
Adhesion of CHO cells to fibronectin is mediated by functionally and structurally distinct adhesion plaques.
Topics: Animals; Cell Adhesion; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Endocytosis; Fibronectins; Humans; Integrins; Microscopy, Fluorescence; Monensin; Receptor Aggregation; Receptors, Fibronectin; Signal Transduction; Talin | 1993 |
Brefeldin A blocks the response of cultured cells to cholera toxin. Implications for intracellular trafficking in toxin action.
Topics: Adenocarcinoma; Adenylyl Cyclases; Animals; Biological Transport; Brefeldin A; Cell Line; Chloroquine; Cholera Toxin; Colonic Neoplasms; Cyclic AMP; Cyclopentanes; Enzyme Activation; Glioma; Golgi Apparatus; Humans; Isoproterenol; Kinetics; Monensin; Mycotoxins; Rats; Time Factors; Tumor Cells, Cultured | 1993 |
Entry of poliovirus into cells does not require a low-pH step.
Topics: Amantadine; Animals; Anti-Bacterial Agents; Autoradiography; Cadaverine; Cell Line; Chloroquine; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Hydrogen-Ion Concentration; Macrolides; Methionine; Models, Biological; Monensin; Poliovirus; Proton-Translocating ATPases; Semliki forest virus; Sulfur Radioisotopes; Vesicular stomatitis Indiana virus; Viral Proteins; Virus Replication | 1993 |
Uptake of ferritin by isolated rat hepatocytes. Effect of metabolic inhibitors and iron.
Topics: Animals; Antimetabolites; Cell Survival; Chloroquine; Endocytosis; Ferritins; Iodine Radioisotopes; Iron; Leupeptins; Liver; Monensin; Rats; Rats, Wistar; Trypan Blue | 1993 |
Cytotoxic activity of lutropin-gelonin conjugate in mouse Leydig tumor cells: potentiation of the hormonotoxin activity by different drugs.
Topics: Animals; Antineoplastic Agents; Chloroquine; Drug Screening Assays, Antitumor; Drug Synergism; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Mice; Monensin; Neoplasm Proteins; Plant Proteins; Progesterone; Protein Synthesis Inhibitors; Quinacrine; Receptors, LH; Ribosome Inactivating Proteins, Type 1; Testicular Neoplasms; Tumor Cells, Cultured; Verapamil | 1993 |
Pertussis toxin-catalyzed ADP-ribosylation of Gi-2 and Gi-3 in CHO cells is modulated by inhibitors of intracellular trafficking.
Topics: Adenosine Diphosphate Ribose; Animals; Chloroquine; CHO Cells; Cricetinae; Cytochalasin D; Endocytosis; GTP-Binding Proteins; Monensin; Nocodazole; Pertussis Toxin; Virulence Factors, Bordetella | 1996 |
A vacuolar-type proton ATPase mediates acidification of plasmalemmal vesicles during potocytosis.
Topics: Acids; Ammonium Chloride; Animals; Anti-Bacterial Agents; Antimalarials; Biological Transport; Cell Compartmentation; Cell Line; Cell Membrane; Chloroquine; Enzyme Inhibitors; Epithelial Cells; Epithelium; Folic Acid; Haplorhini; Intracellular Membranes; Ionophores; Kidney; Macrolides; Monensin; Octoxynol; Oligomycins; Proton-Translocating ATPases; Protons; Tetrahydrofolates; Vacuoles | 1996 |
Degradation of radioiodinated B cell monoclonal antibodies: inhibition via a FCgamma-receptor-II-mediated mechanism and by drugs.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; B-Lymphocytes; Biological Transport; Burkitt Lymphoma; Calcium Channel Blockers; Cell Adhesion Molecules; Chloroquine; Colchicine; Etoposide; Humans; Immunoglobulin Isotypes; Immunotoxins; Iodine Radioisotopes; Lectins; Leukemia, B-Cell; Mice; Monensin; Paclitaxel; Radioimmunotherapy; Receptors, IgG; Sialic Acid Binding Ig-like Lectin 2; Verapamil; Vinblastine; Vincristine | 1996 |
Pathway of rubella virus infectious entry into Vero cells.
Topics: Ammonium Chloride; Animals; Chlorocebus aethiops; Chloroquine; Hydrogen-Ion Concentration; Methylamines; Monensin; Rubella virus; Transfection; Vero Cells | 1996 |
Inhibition of cellular processing of surfactant protein C by drugs affecting intracellular pH gradients.
Topics: Animals; Anti-Bacterial Agents; Antibodies; Cells, Cultured; Chloroquine; Enzyme Inhibitors; Epitopes; Hydrogen-Ion Concentration; Ionophores; Kinetics; Lung; Macrolides; Methylamines; Models, Biological; Monensin; Protein Precursors; Protein Processing, Post-Translational; Proteolipids; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Sulfur Radioisotopes; Time Factors; Vacuoles | 1996 |
Cholesterol homeostasis is modulated by amphiphiles at transcriptional and post-transcriptional loci.
Topics: 3T3 Cells; Animals; Anticholesteremic Agents; Chloramphenicol O-Acetyltransferase; Chloroquine; Cholesterol; Dactinomycin; Estradiol; Gene Expression Regulation; Homeostasis; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mice; Monensin; Protein Processing, Post-Translational; Receptors, LDL; RNA, Messenger; Surface-Active Agents; Transcription, Genetic | 1996 |
In vitro fusion of endocytic vesicles: effects of reagents that alter endosomal pH.
Topics: Anti-Bacterial Agents; Cell Fusion; Chloroquine; Endocytosis; Endosomes; Ethylmaleimide; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrogen-Ion Concentration; Macrolides; Monensin; Ricin; Tumor Cells, Cultured | 1996 |
Tumor necrosis factor soluble receptor 75: the principal receptor form released by human alveolar macrophages and monocytes in the presence of interferon gamma.
Topics: Animals; Antigens, CD; Cells, Cultured; Chloroquine; Colchicine; Culture Media; Growth Substances; Humans; Interferon-gamma; L Cells; Lipopolysaccharides; Macrophage Activation; Macrophages, Alveolar; Mice; Microtubules; Monensin; Monocytes; Protein Synthesis Inhibitors; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Carboxylic ionophores in malaria chemotherapy: the effects of monensin and nigericin on Plasmodium falciparum in vitro and Plasmodium vinckei petteri in vivo.
Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Malaria; Mice; Monensin; Nigericin; Plasmodium; Species Specificity | 1996 |
Expression of mycobacterial antigens on murine dissociated Schwann cells infected with Mycobacterium leprae.
Topics: Animals; Antibodies, Bacterial; Antifungal Agents; Antigens, Bacterial; Antimalarials; Cell Membrane; Chloroquine; Enzyme-Linked Immunosorbent Assay; Interferon-gamma; Kinetics; Leprosy; Mice; Monensin; Mycobacterium leprae; Recombinant Proteins; Schwann Cells | 1997 |
Entry of mouse hepatitis virus into cells by endosomal and nonendosomal pathways.
Topics: Animals; Anti-Bacterial Agents; Cell Fusion; Cell Membrane; Chloroquine; Endocytosis; Endosomes; Enzyme Inhibitors; Giant Cells; Hydrogen-Ion Concentration; Ionophores; Macrolides; Mice; Monensin; Murine hepatitis virus; Time Factors; Tumor Cells, Cultured | 1997 |
Porcine submaxillary mucin forms disulfide-linked multimers through its amino-terminal D-domains.
Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Chloroquine; COS Cells; Cyclopentanes; Disulfides; Glycosylation; Golgi Apparatus; Hydrogen-Ion Concentration; Macrolides; Molecular Sequence Data; Monensin; Mucins; Protein Conformation; Proton-Translocating ATPases; Recombinant Proteins; Submandibular Gland; Swine; Transfection | 1998 |
Entry of African swine fever virus into Vero cells and uncoating.
Topics: 2,4-Dinitrophenol; Adsorption; African Swine Fever Virus; Ammonium Chloride; Animals; Chlorocebus aethiops; Chloroquine; Cytochalasin B; Cytoskeleton; Demecolcine; Endocytosis; Endosomes; Lysosomes; Membrane Fusion; Monensin; Sodium Azide; Vero Cells | 1998 |
Ca2+ depletion from granules inhibits exocytosis. A study with insulin-secreting cells.
Topics: Animals; Calcium; Chloroquine; Cytoplasmic Granules; Electric Conductivity; Exocytosis; Hydrogen-Ion Concentration; Insulin; Ionophores; Islets of Langerhans; Monensin; Tumor Cells, Cultured | 1998 |
The effect of monensin and chloroquine on the endocytosis and toxicity of chimeric toxins.
Topics: Chloroquine; Endocytosis; Humans; Hydrogen-Ion Concentration; Immunotoxins; Intracellular Fluid; Male; Monensin; Prostatic Neoplasms; Protein Synthesis Inhibitors; Receptors, Transferrin; Ricin; Saponins; Transferrin; Tumor Cells, Cultured | 1998 |
The deletion of the C-terminal tail and addition of an endoplasmic reticulum targeting signal to Alzheimer's amyloid precursor protein change its localization, secretion, and intracellular proteolysis.
Topics: Adenovirus Early Proteins; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biotinylation; Brefeldin A; Chloroquine; COS Cells; Endoplasmic Reticulum; Fluorescent Antibody Technique; Humans; Kinetics; Microscopy, Fluorescence; Monensin; Protein Sorting Signals; Recombinant Fusion Proteins; Transfection | 1998 |
Phosphorylation of arylsulphatase A occurs through multiple interactions with the UDP-N-acetylglucosamine-1-phosphotransferase proximal and distal to its retrieval site by the KDEL receptor.
Topics: Acetylglucosamine; Ammonium Chloride; Cerebroside-Sulfatase; Chloroquine; Chromatography, High Pressure Liquid; Glucose; Glycosylation; Golgi Apparatus; Hydrogen-Ion Concentration; Hydrolysis; Lysosomes; Mannose; Mannosephosphates; Monensin; N-Acetylneuraminic Acid; Oligosaccharides; Phosphorylation; Primaquine; Protein Sorting Signals; Receptor, IGF Type 2; Receptors, Peptide; Transferases (Other Substituted Phosphate Groups) | 1999 |
Adenovirus cellular receptor site recirculation of HeLa cells upon receptor-mediated endocytosis is not low pH-dependent.
Topics: Adenoviruses, Human; Amantadine; Ammonium Chloride; Chloroquine; Cycloheximide; Endocytosis; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Methionine; Monensin; Nigericin; Receptors, Virus; Sulfur Radioisotopes | 1999 |
MAL, an integral element of the apical sorting machinery, is an itinerant protein that cycles between the trans-Golgi network and the plasma membrane.
Topics: Ammonium Chloride; Animals; Biological Transport; Biotinylation; Brefeldin A; Cell Line; Cell Membrane; Chloroquine; COS Cells; Dogs; Endosomes; Flow Cytometry; Fluorescent Antibody Technique; Glycosylation; Golgi Apparatus; Membrane Transport Proteins; Monensin; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Neuraminidase; Nocodazole; Oligopeptides; Peptides; Proteolipids; Recombinant Proteins; Transfection; Transferrin | 1999 |
Visualization of acidic compartments in cultured osteoclasts by use of an acidotrophic amine as a marker for low pH.
Topics: Acetazolamide; Acids; Actins; Adenosine Triphosphatases; Ammonium Chloride; Animals; Anti-Bacterial Agents; Antirheumatic Agents; Biomarkers; Carbonic Anhydrase Inhibitors; Cell Compartmentation; Cells, Cultured; Chloroquine; Dinitrobenzenes; Enzyme Inhibitors; Extracellular Space; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Hydrogen-Ion Concentration; Ionophores; Macrolides; Microscopy, Electron; Monensin; Nigericin; Osteoclasts; Rabbits; Vacuoles | 1999 |
Activation of protein kinase A modulates trafficking of the human cardiac sodium channel in Xenopus oocytes.
Topics: Animals; Chloroquine; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Humans; Ion Channel Gating; Monensin; Myocardium; Oocytes; Recombinant Proteins; Sodium Channels; Xenopus laevis | 2000 |
Hydrogen ion gradients across the mitochondrial, endosomal and plasma membranes in bloodstream forms of trypanosoma brucei solving the three-compartment problem.
Topics: Animals; Antimalarials; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane; Chloroquine; Dimethadione; Dose-Response Relationship, Drug; Endosomes; Glycerol; Hydrogen-Ion Concentration; Ionophores; Kinetics; Membrane Potentials; Methylamines; Mitochondria; Monensin; Nystatin; Oligomycins; Potassium Chloride; Proton-Motive Force; Protons; Pyruvates; Sodium; Time Factors; Trypanosoma brucei brucei; Uncoupling Agents; Valinomycin; Water | 2000 |
Lysosomal involvement in hepatocyte cytotoxicity induced by Cu(2+) but not Cd(2+).
Topics: Acridine Orange; Adenine; Animals; Aurothioglucose; Cadmium; Cell Death; Chloroquine; Copper; Endopeptidases; Enzyme Activation; Gentamicins; Leupeptins; Lipid Peroxidation; Liver; Lysosomes; Male; Methylamines; Monensin; Oxidation-Reduction; Pepstatins; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2001 |
Release of amines from acidified stores following accumulation by Transport-P.
Topics: Antidepressive Agents; Biological Transport; Boron Compounds; Cells, Cultured; Chloroquine; Desipramine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Hypothalamus; Monensin; Prazosin; Temperature | 2001 |
Biosynthesis and processing of cathepsin K in cultured human osteoclasts.
Topics: Androstadienes; Antibodies; Bone Resorption; Cathepsin K; Cathepsins; Cells, Cultured; Chloroquine; Enzyme Inhibitors; Humans; Immunohistochemistry; Monensin; Osteoclasts; Phosphoinositide-3 Kinase Inhibitors; Protein Processing, Post-Translational; Wortmannin | 2001 |
Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparum.
Topics: Ammonium Chloride; Animals; Antimalarials; Artemisinins; Biotin; Blotting, Western; Chloroquine; Dextrans; Endocytosis; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Hemoglobins; Mefloquine; Microscopy, Electron; Microscopy, Fluorescence; Monensin; Plasmodium falciparum; Quinolones; Sesquiterpenes; Transport Vesicles; Vacuoles | 2004 |
Vacuolar ATPase regulates zymogen activation in pancreatic acini.
Topics: Amylases; Animals; Calcium; Carbachol; Cell Membrane; Cells, Cultured; Ceruletide; Chloroquine; Chymotrypsin; Enzyme Activation; Enzyme Precursors; Hydrogen-Ion Concentration; Macrolides; Male; Monensin; Pancreas; Protein Subunits; Protein Transport; Rats; Rats, Sprague-Dawley; Solubility; Thapsigargin; Trypsin; Vacuolar Proton-Translocating ATPases | 2005 |
Tyrosinase-related protein-2 and -1 are trafficked on distinct routes in B16 melanoma cells.
Topics: Animals; Cell Line, Tumor; Chloroquine; Endoplasmic Reticulum; Golgi Apparatus; Intramolecular Oxidoreductases; Melanoma, Experimental; Membrane Glycoproteins; Mice; Monensin; Oxidoreductases; Protein Transport | 2005 |
Intracellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins E; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Brefeldin A; Chloroquine; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Cyclodextrins; Female; Fluorescent Antibody Technique; Humans; Lipoproteins, VLDL; Microscopy, Confocal; Monensin; Protein Transport | 2006 |
cAMP-PKA signaling pathway regulates bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts.
Topics: Animals; Antibodies; Bone Resorption; Carbazoles; Cathepsin K; Cathepsins; Cells, Cultured; Chloroquine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Lysosomes; Mannose; Mice; Monensin; Naphthalenes; Osteoclasts; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrroles; Receptor, IGF Type 2; Signal Transduction; Sulfonamides | 2006 |
Modeling cytoplasmic release of encapsulated oligonucleotides from cationic liposomes.
Topics: Animals; Capsules; Chloroquine; Cholesterol; Cytoplasm; Endocytosis; Endosomes; Flow Cytometry; Fluorescein-5-isothiocyanate; Gene Transfer Techniques; Intracellular Membranes; Kinetics; Lipids; Liposomes; Mice; Microscopy, Fluorescence; Monensin; NIH 3T3 Cells; Oligodeoxyribonucleotides, Antisense; Phosphates; Phospholipids; Sodium Azide; Spectrometry, Fluorescence; Static Electricity; Temperature | 2007 |
Cholesterol efflux via HDL resecretion occurs when cholesterol transport out of the lysosome is impaired.
Topics: Androstenes; Animals; Biological Transport; Carrier Proteins; Chloroquine; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Endocytosis; Fibroblasts; Humans; Imipramine; Intracellular Signaling Peptides and Proteins; Lipoproteins, HDL; Lysosomes; Membrane Glycoproteins; Monensin; Niemann-Pick C1 Protein; Scavenger Receptors, Class B | 2007 |
Inhibition of betanodavirus infection by inhibitors of endosomal acidification.
Topics: Ammonium Chloride; Animals; Antiviral Agents; Cells, Cultured; Chloroquine; Cytopathogenic Effect, Viral; Endocytosis; Endosomes; Hydrogen-Ion Concentration; Macrolides; Monensin; Nodaviridae | 2007 |
Studies on uptake and intracellular processing of infectious pancreatic necrosis virus by Atlantic cod scavenger endothelial cells.
Topics: Animals; Antiprotozoal Agents; Birnaviridae Infections; Chloroquine; Endocytosis; Endothelial Cells; Fish Diseases; Gadus morhua; Infectious pancreatic necrosis virus; Iodine Radioisotopes; Ligands; Monensin; Receptors, Virus; Time Factors; Virus Replication | 2007 |
Inhibition of endosome-lysosome system acidification enhances porcine circovirus 2 infection of porcine epithelial cells.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Circovirus; Endosomes; Epithelial Cells; Ionophores; Lysosomes; Monensin; Serine Endopeptidases; Swine; Virus Attachment | 2008 |
Increased yield of porcine circovirus-2 by a combined treatment of PK-15 cells with interferon-gamma and inhibitors of endosomal-lysosomal system acidification.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Circovirus; Endosomes; Enzyme Inhibitors; Immunologic Factors; Interferon-gamma; Monensin; Swine | 2008 |
The effect of protein transport inhibitors on the production of extracellular DNA.
Topics: Antirheumatic Agents; Base Sequence; Cell Line; Chloroquine; Cytochalasin B; DNA; Enzyme Inhibitors; Glyburide; Humans; Hypoglycemic Agents; Ionophores; Methylamines; Molecular Sequence Data; Monensin; Ouabain; Protein Transport; Sequence Analysis, DNA | 2008 |
Endosomal trafficking of HIV-1 gag and genomic RNAs regulates viral egress.
Topics: Biological Transport; Blotting, Western; Calcium Chloride; Cell Line, Tumor; Chloroquine; Endosomes; Fluorescent Antibody Technique; gag Gene Products, Human Immunodeficiency Virus; HIV-1; Humans; In Situ Hybridization, Fluorescence; Ionophores; Luminescent Proteins; Microscopy, Electron; Monensin; Nocodazole; Recombinant Fusion Proteins; RNA Transport; RNA, Small Interfering; RNA, Viral; SNARE Proteins; Time Factors; Transfection | 2009 |
Disruption of lysosome function promotes tumor growth and metastasis in Drosophila.
Topics: Animals; Chloroquine; Crosses, Genetic; Drosophila; Genotype; Green Fluorescent Proteins; Humans; Lysosomes; Models, Genetic; Monensin; Neoplasm Metastasis; Neoplasms; ras Proteins; RNA Interference; Vesicular Transport Proteins | 2010 |
pH-sensitive capsules as intracellular optical reporters for monitoring lysosomal pH changes upon stimulation.
Topics: Amiloride; Chloroquine; Fluorescence; Hydrogen-Ion Concentration; Lysosomes; Macrolides; Monensin | 2012 |
Nigericin-induced impairment of autophagic flux in neuronal cells is inhibited by overexpression of Bak.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; bcl-2 Homologous Antagonist-Killer Protein; Cell Line; Cell Line, Tumor; Cells, Cultured; Chloroquine; Embryo, Mammalian; Fibroblasts; HEK293 Cells; Humans; Immunoblotting; Mice; Mice, Knockout; Microscopy, Confocal; Microscopy, Electron; Microtubule-Associated Proteins; Monensin; Neurons; Nigericin; Proton Ionophores; RNA Interference; Vacuoles | 2012 |
Entry of Newcastle Disease Virus into the host cell: role of acidic pH and endocytosis.
Topics: Animals; Cell Membrane; Chloroquine; CHO Cells; Cricetulus; Dynamins; Endocytosis; Endosomes; HeLa Cells; Host-Pathogen Interactions; Humans; Hydrazones; Hydrogen-Ion Concentration; Indoles; Macrolides; Maleimides; Membrane Fusion; Monensin; Newcastle disease virus; Protein Kinase C; Receptors, Virus; Thermodynamics; Virion; Virus Internalization | 2014 |
V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation.
Topics: Animals; Autophagy; Bacterial Proteins; Cell Line; Chloroquine; Endosomes; Entosis; Humans; Lipids; Lysosomes; Mice; Microtubule-Associated Proteins; Monensin; Osmosis; Phagocytosis; Phosphatidylinositol Phosphates; Vacuolar Proton-Translocating ATPases; Water | 2015 |
Acidocalcisome is required for autophagy in Trypanosoma brucei.
Topics: Autophagy; Calcium; Chloroquine; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Lysosomes; Macrolides; Microscopy, Fluorescence; Monensin; Organelles; Phagosomes; Phosphates; Protozoan Proteins; Trypanosoma brucei brucei | 2014 |
Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Antimalarials; Biological Transport, Active; Cells, Cultured; Chloroquine; Down-Regulation; Drug Interactions; Female; Flow Cytometry; Gene Expression Regulation; HEK293 Cells; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Kinetics; Liver; Liver-Specific Organic Anion Transporter 1; Macrolides; Male; Middle Aged; Monensin; Young Adult | 2016 |
Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter.
Topics: Amodiaquine; Antimalarials; Artemisinins; Calcium; Cells, Cultured; Chloroquine; Drug Resistance, Multiple; Erythrocytes; Gene Expression; Hemoglobins; Host-Parasite Interactions; Humans; Ion Transport; Ionophores; Membrane Transport Proteins; Monensin; Mutation; Nigericin; Plasmodium falciparum; Protozoan Proteins; Pyrrolidinones | 2018 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |