chloroquine has been researched along with miltefosine in 80 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 18 (22.50) | 29.6817 |
2010's | 55 (68.75) | 24.3611 |
2020's | 7 (8.75) | 2.80 |
Authors | Studies |
---|---|
Bringmann, G; Brun, R; Christensen, SB; Dalsgaard, PW; Dreyer, M; Faber, JH; Jaroszewski, JW; Maksimenka, K; Mbago, F; Ndangalasi, H; Reichert, M; Staerk, D | 1 |
Bringmann, G; Brun, R; Christensen, SB; Dalsgaard, PW; Dreyer, M; Faber, JH; Jaroszewski, JW; Mbago, F; Ndangalasi, H; Staerk, D | 1 |
Figadère, B; Fournet, A; Franck, X; Hocquemiller, R; Mahieux, R; Prina, E | 1 |
Bringmann, G; Brun, R; Dreyer, M; Hadi, HA; Heubl, G; Meimberg, H; Rischer, H; Wolf, K | 1 |
Brun, R; Cimanga, K; Dommisse, R; Hostyn, S; Kaiser, M; Lemière, G; Maes, BU; Mátyus, P; Pieters, L; Van Miert, S; Vlietinck, A | 1 |
Ahua, KM; Brun, R; Diallo, D; Hay, AE; Hostettmann, K; Ioset, JR | 1 |
Bringmann, G; Brun, R; Kaiser, M; Neumann, S | 1 |
Brun, R; Gunzenhauser, S; Senn, M; Séquin, U | 1 |
Brun, R; Kaiser, M; Kuettel, S; Perozzo, R; Scapozza, L; Zambon, A | 1 |
Arai, C; Brun, R; Ge, JF; Ihara, M; Kaiser, M; Wittlin, S | 1 |
Castanys, S; Castanys-Muñoz, E; Gamarro, F; Pérez-Victoria, JM | 1 |
Brun, R; Kehraus, S; König, GM; Krick, A; Pontius, A | 1 |
Brun, R; Kaiser, M; Musonda, CC; Whitlock, GA; Witty, MJ | 1 |
Baell, JB; Brun, R; Charman, WN; Fairlamb, AH; Holloway, GA; Kaiser, M; Kostewicz, E; Novello, PM; Parisot, JP; Richardson, J; Street, IP; Watson, KG | 1 |
Bolognesi, ML; Bongarzone, S; Brun, R; Cavalli, A; Lizzi, F; Luise Krauth-Siegel, R | 1 |
Brun, R; Dardonville, C; Fernández-Fernández, C; Gibbons, SL; Jagerovic, N; Kaiser, M; Nieto, L; Ryan, G | 1 |
Brun, R; Cos, P; Dhooghe, L; Dommisse, R; Hajós, G; Hostyn, S; Kaiser, M; Lemière, G; Maes, BU; Maes, L; Mátyus, P; Nagy, I; Pieters, L; Riedl, Z; Tapolcsányi, P; Van Baelen, G | 1 |
Brun, R; Franzblau, SG; Huang, Q; Kozikowski, AP; Mao, J; Wan, B; Wang, Y | 1 |
Brun, R; Lusvarghi, S; Mazzieri, MR; Pagliero, RJ; Pierini, AB | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Armstrong, T; Baell, JB; Holloway, GA; Novello, PM; Parisot, JP; Street, IP; Thompson, RC; Watson, KG | 1 |
Della Togna, G; Gerwick, WH; Kyle, DE; Linington, RG; Lopez, D; Sanchez, LM; Vesely, BA | 1 |
Amade, P; Cachet, N; Kaiser, M; Regalado, EL; Tasdemir, D; Thomas, OP | 1 |
Baumann, K; Bischof, SK; Bringmann, G; Brun, R; Dreher, J; Gulder, T; Kaiser, M; Moll, H; Müller, S; Stich, A; Winter, C | 1 |
Brun, R; Carballeira, NM; Herman, R; Kappe, SH; Lauinger, IL; Perozzo, R; Sanabria, D; Tarun, A; Tasdemir, D; Zloh, M | 1 |
Carvalho, L; Castanys, S; Gamarro, F; Manzano, JI; Pérez-Victoria, JM | 1 |
Bourguet-Kondracki, ML; Copp, BR; Finlayson, R; Harper, JL; Kaiser, M; Page, MJ; Pearce, AN; Webb, VL | 1 |
Gerth, K; Jansen, R; Mohr, KI; Müller, R; Okanya, PW | 1 |
Anklin, C; Bahar, M; Deng, Y; Doskotch, RW; Drew, ME; Gil, RR; He, S; Kinghorn, AD; Navarro-Vázquez, A; Pandharkar, T; Werbovetz, KA; Zhu, X | 1 |
Chan, ST; Copp, BR; Kaiser, M; Page, MJ; Pearce, AN | 1 |
Brun, R; Ge, JF; Ihara, M; Kaiser, M; Liu, BQ; Shi, XL; Wittlin, S | 1 |
Anizon, F; Bouchikhi, F; Brun, R; Moreau, P | 1 |
Brun, R; Huang, TL; Kaiser, M; Mayence, A; Vanden Eynde, JJ; Yarlett, N | 1 |
Dürüst, Y; Kaiser, M; Karakuş, H; Tasdemir, D | 1 |
Boshoff, HI; Boyd, PD; Copp, BR; Kaiser, M; McCracken, ST | 1 |
Bettis, S; Brun, R; Fomovska, A; Huang, Q; Kaiser, M; Kozikowski, AP; McLeod, R; Mui, E; Pieroni, M; Stec, J; Witola, WH | 1 |
Azas, N; Casanova, M; Castera-Ducros, C; Dumètre, A; Hutter, S; Kraiem-M'rabet, M; Laget, M; Mbatchi, L; Paloque, L; Rathelot, P; Rault, S; Remusat, V; Vanelle, P; Verhaeghe, P | 1 |
Agarwal, H; Bahar, M; Brun, R; Cason, E; Doskotch, RW; Drew, ME; Endeshaw, M; He, S; Kaiser, M; Kinghorn, AD; Li, C; Mahasenan, KV; Munde, M; Pandharkar, T; Werbovetz, KA; Wilson, WD; Zhu, X | 1 |
Chauhan, PM; Gupta, S; Khan, S; Kidwai, S; Puri, SK; Shivahare, R; Srivastava, K; Tyagi, V | 1 |
Copp, BR; Kaiser, M; Liew, LP | 1 |
Barker, D; Rye, CE | 1 |
El Sayed, I; Inokuchi, T; Kaiser, M; Lu, WJ; Maeda, T; Mei, ZW; Pang, CQ; Peng, W; Wang, L | 1 |
Buisson, D; Fromentin, Y; Gaboriaud-Kolar, N; Grellier, P; Lallemand, MC; Lenta, BN; Loiseau, PM; Michel, S; Mouray, E; Wansi, JD | 1 |
Arafa, RK; Boykin, DW; Brun, R; Ismail, MA; Jones, SK; Pandharkar, T; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA; Zhu, X | 1 |
Almohaywi, B; Avery, VM; Baell, JB; Campbell, M; Charman, SA; Ferrins, L; Hyland, C; Jones, AJ; Kaiser, M; Rahmani, R; Ryan, E; Smith, J; Sykes, ML; Teston, E; White, KL; Yin, J | 1 |
Abada, Z; Akagah, B; Cojean, S; Ferrié, L; Figadère, B; Loiseau, PM; Lormier, AT; Pomel, S | 1 |
Brun, R; Harel, D; Prinz, H; Schepmann, D; Schmidt, TJ; Wünsch, B | 1 |
Botta, B; Brun, R; Costi, R; De Vita, D; Di Santo, R; Friggeri, L; Kaiser, M; Moraca, F; Scipione, L; Tortorella, S; Zamperini, C | 1 |
Avery, VM; Baell, JB; Bergström, CA; Charman, SA; Ferrins, L; Gazdik, M; Jones, AJ; Kaiser, M; Rahmani, R; Ryan, E; Sykes, ML; Varghese, S; White, KL | 1 |
Bode, HB; Kaiser, M; Nollmann, FI; Reimer, D; Schultz, K | 1 |
Ariën, KK; Augustyns, K; Cos, P; Dirié, B; Heeres, J; Joossens, J; Lewi, PJ; Lyssens, S; Maes, L; Michiels, J; Van der Veken, P; Vanham, G; Venkatraj, M | 1 |
Battistuzzi, G; Giannini, G; Vignola, D | 1 |
Dardonville, C; Kaiser, M; Montalvo-Quirós, S; Taladriz-Sender, A | 1 |
Bosc, D; Cojean, S; Dubois, J; Franco, CH; Freitas-Junior, LH; Grellier, P; Loiseau, PM; Moraes, CB; Mouray, E | 1 |
De Vita, D; Di Santo, R; Maes, L; Matheeussen, A; Moraca, F; Pandolfi, F; Scipione, L; Tortorella, S; Zamperini, C | 1 |
Dong, G; Liu, N; Sheng, C; Wang, Y; Wu, S | 1 |
Bringmann, G; Brun, R; Brünnert, D; Chatterjee, M; Efferth, T; Feineis, D; Kaiser, M; Li, J; Mudogo, V; Seo, EJ; Seupel, R | 1 |
Back, TG; Brun, R; Kaiser, M; Manivannan, S; Pastor, A; Snyder, FF; Tran, HA; Wen, X; Zheng, Z | 1 |
Brun, R; Kaiser, M; Mazzieri, MR; Nieto, MJ; Pagliero, RJ | 1 |
Chianese, G; Erpenbeck, D; Kaiser, M; Luciano, P; Merten, C; Silber, J; Tasdemir, D; Topaloglu, B | 1 |
Awale, S; Bringmann, G; Bruhn, T; Brun, R; Feineis, D; Kaiser, M; Li, J; Mudogo, V; Seupel, R | 1 |
Augustyns, K; Caljon, G; Heeres, J; Joossens, J; Lewi, PJ; Maes, L; Salado, IG; Van der Veken, P; Venkatraj, M | 1 |
Arévalo-Ruiz, M; Belmonte-Reche, E; Campos-Salinas, J; Doria, F; Freccero, M; Guédin, A; López-Rubio, JJ; Martínez-García, M; Maynadier, M; Mergny, JL; Morales, JC; Pérez-Victoria, JM; Zuffo, M | 1 |
Bringmann, G; Brun, R; Efferth, T; Feineis, D; Kaiser, M; Mudogo, V; Seo, EJ; Tshitenge, DT | 1 |
Augustyns, K; Baán, A; Caljon, G; Kiekens, F; Maes, L; Matheeussen, A; Salado, IG; Van der Veken, P; Verdeyen, T | 1 |
Aliabadi, A; De Mieri, M; Ebrahimi, SN; Farimani, MM; Hamburger, M; Kaiser, M; Khodaei, B; Moradi, H | 1 |
Brun, R; Calvet, CM; Costi, R; De Leo, A; De Vita, D; Di Santo, R; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Tudino, V | 1 |
Bode, HB; Cai, X; Kaiser, M; Zhao, L | 1 |
Danton, O; Hamburger, M; Kaiser, M; Moridi Farimani, M; Nejad Ebrahimi, S; Neuburger, M; Potterat, O; Ramseyer, J; Salehi, P; Tabefam, M | 1 |
Battista, MR; Brun, R; Calvet, CM; Cirilli, R; Costi, R; De Leo, A; De Vita, D; Di Marco, A; Di Santo, R; Faggi, C; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pepe, G; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Summa, V; Tudino, V | 1 |
Awale, S; Bringmann, G; Bruhn, T; Brun, R; Feineis, D; Kaiser, M; Mudogo, V; Schmidt, D; Tshitenge, DT; Würthner, F | 1 |
Buckner, FS; Cal, M; Davis, PH; Kaiser, M; Lepesheva, GI; Sanford, AG; Vennerstrom, JL; Wallick, AI; Wang, X | 1 |
Al-Harrasi, A; Babanezhad Harikandei, K; Bararjanian, M; Ebrahimi, SN; Kaiser, M; Salehi, P | 1 |
Awori, RM; Bode, HB; Groß, J; Kaiser, M; Opatz, T; Zhao, L | 1 |
Bringmann, G; Feineis, D; Kaiser, M; Lombe, BK; Mudogo, V | 1 |
Börgel, F; Jabor, VAP; Kaiser, M; Krauth-Siegel, RL; Lehmkuhl, K; Nonato, MC; Schepmann, D; Schmidt, TJ; Uth, JF; Wünsch, B | 1 |
Brun, R; Celik, I; Doganc, F; Eren, G; Goker, H; Kaiser, M | 1 |
Cojean, S; Ferrié, L; Figadère, B; Le Pape, P; Loiseau, PM; Maciuk, A; Nguyen, LT; Pinet, A; Vásquez-Ocmín, P | 1 |
Carvalho, C; Cordeiro da Silva, A; Duarte, D; Kijjoa, A; Long, S; Moreira, R; Nogueira, F; Oliveira, R; Palmeira, A; Pinto, MMM; Resende, DISP; Santarém, N; Silva, AMS; Sousa, E | 1 |
Croft, SL; Murdan, S; Van Bocxlaer, K; Wijnant, GJ; Yardley, V | 1 |
1 review(s) available for chloroquine and miltefosine
Article | Year |
---|---|
Tackling Fungal Resistance by Biofilm Inhibitors.
Topics: Animals; Antifungal Agents; Biofilms; Drug Discovery; Drug Resistance, Fungal; Fungi; Humans; Models, Molecular; Mycoses; Small Molecule Libraries | 2017 |
79 other study(ies) available for chloroquine and miltefosine
Article | Year |
---|---|
Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described species Ancistrocladus tanzaniensis.
Topics: Alkaloids; Animals; Antiprotozoal Agents; Isoquinolines; Leishmania donovani; Magnoliopsida; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Stereoisomerism; Tanzania; Trypanosoma cruzi | 2003 |
Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis.
Topics: Alkaloids; Animals; Antimalarials; Isoquinolines; Leishmania donovani; Magnoliopsida; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal; Plasmodium falciparum; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2004 |
Biological evaluation of substituted quinolines.
Topics: Animals; Antiparasitic Agents; Cell Line; Cell Transformation, Viral; Evaluation Studies as Topic; HTLV-I Infections; Leishmania; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Trypanosoma | 2004 |
Ancistrobenomine a, the first naphthylisoquinoline oxygenated at Me-3, and related 5,1'-coupled alkaloids, from the "new" plant species ancistrocladusbenomensis.
Topics: Alkaloids; Animals; Antiprotozoal Agents; Isoquinolines; Leishmania donovani; Malaysia; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Plasmodium falciparum; Trypanosoma | 2004 |
Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound.
Topics: Alkaloids; Animals; Antimalarials; Apocynaceae; Indole Alkaloids; Indoles; Molecular Structure; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2005 |
Limonoid orthoacetates and antiprotozoal compounds from the roots of Pseudocedrela kotschyi.
Topics: Animals; Antiprotozoal Agents; Leishmania donovani; Limonins; Mali; Meliaceae; Molecular Structure; Plant Roots; Plants, Medicinal; Plasmodium falciparum; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2007 |
Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids.
Topics: Alkaloids; Animals; Antiprotozoal Agents; Eukaryota; Isoquinolines; Myoblasts, Skeletal | 2008 |
Antiprotozoal polyacetylenes from the Tanzanian medicinal plant Cussonia zimmermannii.
Topics: Animals; Antiprotozoal Agents; Araliaceae; Leishmania donovani; Molecular Structure; Plants, Medicinal; Plasmodium falciparum; Polyynes; Tanzania; Trypanosoma brucei rhodesiense | 2007 |
Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives.
Topics: Animals; Antimalarials; Leishmania donovani; Morpholines; Plasmodium falciparum; Pyrazoles; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma | 2007 |
Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Chloroquine; Drug Resistance; Leishmania donovani; Oxazines; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2008 |
Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement.
Topics: Aminoquinolines; Animals; Antiprotozoal Agents; ATP-Binding Cassette Transporters; Base Sequence; Biological Transport, Active; Chloroquine; DNA, Protozoan; Drug Resistance; Fluorescent Dyes; Genes, Protozoan; Humans; Leishmania infantum; Leishmaniasis, Visceral; Lipid Bilayers; Phosphorylcholine; Protozoan Proteins; Recombinant Proteins; Transformation, Genetic | 2008 |
Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus Chaetomium sp.
Topics: Animals; Antiprotozoal Agents; Bacillus megaterium; Chaetomium; Chlorella; Drug Screening Assays, Antitumor; Escherichia coli; Leishmania donovani; Marine Biology; Microbial Sensitivity Tests; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Trypanosoma cruzi; Xanthones | 2008 |
Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity.
Topics: Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Leishmania donovani; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship | 2009 |
Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity.
Topics: Animals; Antiparasitic Agents; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Molecular Structure; NADH, NADPH Oxidoreductases; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis | 2009 |
Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase.
Topics: Animals; Antiparasitic Agents; Cell Line; Computer Simulation; Drug Design; Enzyme Inhibitors; Glutathione Reductase; Humans; NADH, NADPH Oxidoreductases; Quinazolines; Rats; Structure-Activity Relationship; Trypanosoma cruzi | 2009 |
Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives.
Topics: Animals; Antiprotozoal Agents; Cell Line; Eukaryota; Female; Inhibitory Concentration 50; Leishmania donovani; Mice; Molecular Structure; Parasitic Sensitivity Tests; Piperidines; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2009 |
Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues.
Topics: Animals; Antimalarials; Antineoplastic Agents; Indole Alkaloids; Mice; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship | 2009 |
Searching for new cures for tuberculosis: design, synthesis, and biological evaluation of 2-methylbenzothiazoles.
Topics: Antimalarials; Antitubercular Agents; Benzothiazoles; Drug Design; Isoxazoles; Models, Molecular; Mycobacterium tuberculosis; Phenylacetates; Stereoisomerism; Structure-Activity Relationship; Trypanocidal Agents | 2009 |
Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines.
Topics: Animals; Antiprotozoal Agents; Cell Line; Humans; Leishmania donovani; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Infections; Quinolines; Structure-Activity Relationship; Trypanosoma; Trypanosoma cruzi | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi.
Topics: Animals; Cell Line; Drug Discovery; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds.
Topics: Antiprotozoal Agents; Cyanobacteria; Leishmania donovani; Lipopeptides; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship | 2010 |
Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium.
Topics: Animals; Antiprotozoal Agents; Leishmania donovani; Marine Biology; Nuclear Magnetic Resonance, Biomolecular; Oceans and Seas; Plasmodium falciparum; Porifera; Saponins; Steroids; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2010 |
QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids.
Topics: Alkaloids; Animals; Antimalarials; Isoquinolines; Magnetic Resonance Spectroscopy; Models, Molecular; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared | 2010 |
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections.
Topics: Alkynes; Antimalarials; Binding Sites; Cell Line, Tumor; Computer Simulation; Erythrocytes; Fatty Acid Synthase, Type II; Fatty Acids, Unsaturated; Humans; Kinetics; Liver; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins | 2010 |
Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania major.
Topics: Adenosine Triphosphate; Aminoquinolines; Antiprotozoal Agents; Drug Resistance; Glycolysis; Leishmania major; Pyruvate Kinase | 2011 |
Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp.
Topics: Animals; Antiprotozoal Agents; Indole Alkaloids; Leishmania donovani; Molecular Structure; New Zealand; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Spermidine; Structure-Activity Relationship; Trypanosoma; Urochordata | 2011 |
Marinoquinolines A-F, pyrroloquinolines from Ohtaekwangia kribbensis (Bacteroidetes).
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents; Bacteroidetes; Drug Screening Assays, Antitumor; Female; Humans; India; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Pyrroles; Quinolines | 2011 |
Potent antiprotozoal activity of a novel semi-synthetic berberine derivative.
Topics: Animals; Antiprotozoal Agents; Berberine; Chlorocebus aethiops; Disease Models, Animal; Inhibitory Concentration 50; Leishmania; Leishmaniasis; Malaria; Mice; Models, Molecular; Parasites; Plasmodium falciparum; Protozoan Infections; Trypanosoma brucei brucei; Trypanosomiasis; Vero Cells | 2011 |
Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum.
Topics: Animals; Antimalarials; Carbolines; Chloroquine; Drug Resistance; Molecular Structure; New Zealand; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Stereoisomerism; Urochordata | 2011 |
Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivatives.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Drug Design; Inhibitory Concentration 50; Leishmania donovani; Malaria; Models, Chemical; Molecular Structure; Myoblasts; Oxazines; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridinium Compounds; Rats; Structure-Activity Relationship; Thiazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2011 |
Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis).
Topics: Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Humans; Protozoan Infections | 2011 |
Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents.
Topics: Animals; Antimalarials; Benzimidazoles; Cell Line; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats | 2011 |
Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles.
Topics: Animals; Antiprotozoal Agents; Cell Line; Eukaryota; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Oxadiazoles; Protozoan Infections; Pyrroles; Rats; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Triazoles | 2012 |
Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers.
Topics: Antimalarials; Antitubercular Agents; Coumarins; Dimerization; Fatty Acids, Monounsaturated; Inhibitory Concentration 50; Leishmania donovani; Light; Molecular Structure; Plasmodium falciparum; Pyrones | 2012 |
Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania.
Topics: Antimalarials; Benzamides; Imides; Leishmania donovani; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2012 |
Discovery of a new antileishmanial hit in 8-nitroquinoline series.
Topics: Animals; Antiprotozoal Agents; Drug Discovery; Hep G2 Cells; Humans; Leishmania donovani; Life Cycle Stages; Mice; Nitroquinolines | 2012 |
8,8-dialkyldihydroberberines with potent antiprotozoal activity.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Berberine Alkaloids; Crystallography, X-Ray; Female; Inhibitory Concentration 50; Leishmania donovani; Mice; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma | 2013 |
A natural product inspired hybrid approach towards the synthesis of novel pentamidine based scaffolds as potential anti-parasitic agents.
Topics: Antimalarials; Antiprotozoal Agents; Biological Products; Chalcone; Pentamidine; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship | 2013 |
Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds.
Topics: Acetamides; Animals; Antimalarials; Drug Discovery; Inhibitory Concentration 50; Malaria; Molecular Structure; Plasmodium falciparum; Spermine; Structure-Activity Relationship | 2013 |
Asymmetric synthesis and anti-protozoal activity of the 8,4'-oxyneolignans virolin, surinamensin and analogues.
Topics: Anisoles; Antiprotozoal Agents; Leishmania donovani; Lignans; Molecular Conformation; Parasitic Sensitivity Tests; Plasmodium falciparum | 2013 |
Synthesis and in vitro antimalarial testing of neocryptolepines: SAR study for improved activity by introduction and modifications of side chains at C2 and C11 on indolo[2,3-b]quinolines.
Topics: Alkaloids; Animals; Antimalarials; Cell Line; Chloroquine; Drug Resistance; Indoles; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolines; Rats; Structure-Activity Relationship | 2013 |
Synthesis of novel guttiferone A derivatives: in-vitro evaluation toward Plasmodium falciparum, Trypanosoma brucei and Leishmania donovani.
Topics: Antiprotozoal Agents; Benzophenones; Clusiaceae; Dose-Response Relationship, Drug; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Seeds; Structure-Activity Relationship; Trypanosoma brucei brucei | 2013 |
Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives.
Topics: Animals; Antiprotozoal Agents; Benzene; Chagas Disease; Female; Leishmania donovani; Mice; Mice, Inbred Strains; Models, Chemical; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Terphenyl Compounds; Trypanosoma cruzi | 2013 |
3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.
Topics: Anilides; Animals; Humans; Mice; Myoblasts, Skeletal; Rats; Species Specificity; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2013 |
Synthesis and antiprotozoal activity of original porphyrin precursors and derivatives.
Topics: Antiprotozoal Agents; Dose-Response Relationship, Drug; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium; Porphyrins; Structure-Activity Relationship; Trypanosoma brucei brucei | 2013 |
Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives.
Topics: Antiprotozoal Agents; Biological Products; Chemistry Techniques, Synthetic; Chromans; Inhibitory Concentration 50; Structure-Activity Relationship | 2013 |
New Promising Compounds with in Vitro Nanomolar Activity against Trypanosoma cruzi.
Topics: | 2013 |
Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei.
Topics: Animals; Benzamides; Cell Line; HEK293 Cells; Humans; Microsomes, Liver; Myoblasts; Pyridines; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 2014 |
Xenortide Biosynthesis by Entomopathogenic Xenorhabdus nematophila.
Topics: Chromatography, High Pressure Liquid; Dipeptides; Leishmania; Molecular Structure; Multigene Family; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma brucei brucei; Tryptamines; Xenorhabdus | 2014 |
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.
Topics: Anti-HIV Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 2014 |
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.
Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Malaria; Mice; Parasites; Plasmodium falciparum; Protein Isoforms | 2015 |
Antiprotozoal activity and DNA binding of dicationic acridones.
Topics: Acridines; Acridones; Antiprotozoal Agents; Binding Sites; Cations; DNA; Dose-Response Relationship, Drug; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2015 |
Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors.
Topics: Alkyl and Aryl Transferases; Animals; Antiparasitic Agents; Cell Line; Enzyme Inhibitors; Humans; Imidazoles; Leishmania donovani; Leishmaniasis, Visceral; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis | 2016 |
In vitro screening of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives as antiprotozoal agents and docking studies on Trypanosoma cruzi CYP51.
Topics: Antiprotozoal Agents; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibroblasts; Humans; Imidazoles; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Phenylethyl Alcohol; Structure-Activity Relationship; Trypanosoma cruzi | 2016 |
Dioncophyllines C
Topics: Alkaloids; Antimalarials; Antineoplastic Agents; Humans; Isoquinolines; Magnoliopsida; Molecular Structure; Multiple Myeloma; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Structure-Activity Relationship | 2017 |
Synthesis and activity of nucleoside-based antiprotozoan compounds.
Topics: Animals; Antiprotozoal Agents; Carbon-13 Magnetic Resonance Spectroscopy; Inhibitory Concentration 50; Leishmania donovani; Plasmodium falciparum; Proton Magnetic Resonance Spectroscopy; Spectrophotometry, Infrared; Trypanosoma brucei brucei; Trypanosoma cruzi | 2017 |
Lead selection of antiparasitic compounds from a focused library of benzenesulfonyl derivatives of heterocycles.
Topics: Animals; Antiparasitic Agents; Benzyl Compounds; Dose-Response Relationship, Drug; Heterocyclic Compounds; Leishmania donovani; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2017 |
Antiprotozoal Linear Furanosesterterpenoids from the Marine Sponge Ircinia oros.
Topics: Animals; Antiprotozoal Agents; Furans; Magnetic Resonance Spectroscopy; Molecular Structure; Porifera; Sesquiterpenes; Spectroscopy, Fourier Transform Infrared | 2017 |
Jozilebomines A and B, Naphthylisoquinoline Dimers from the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line.
Topics: Algorithms; Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Congo; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Isoquinolines; Leishmania donovani; Magnoliopsida; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Pancreatic Neoplasms; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Tumor Cells, Cultured | 2017 |
Novel triazine dimers with potent antitrypanosomal activity.
Topics: Animals; Antiprotozoal Agents; Cell Proliferation; Cell Survival; Dimerization; Dose-Response Relationship, Drug; Drug Discovery; Fibroblasts; Humans; Leishmania infantum; Male; Mice; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazines; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2018 |
G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents.
Topics: Animals; Antiparasitic Agents; Cell Line; G-Quadruplexes; Genome, Protozoan; Humans; Imides; Ligands; Naphthalenes; Telomere; Zebrafish | 2018 |
Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities.
Topics: Africa, Central; Alkaloids; Antimalarials; Antineoplastic Agents, Phytogenic; Antiparasitic Agents; Caryophyllales; Cell Line, Tumor; Humans; Isoquinolines; Naphthalenes; Plasmodium falciparum; Quinolines | 2018 |
Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives.
Topics: Animals; Disease Models, Animal; Humans; Mice; Structure-Activity Relationship; Triazines; Tropolone; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2018 |
Phytochemical Study of Salvia leriifolia Roots: Rearranged Abietane Diterpenoids with Antiprotozoal Activity.
Topics: Abietanes; Antimalarials; Antiprotozoal Agents; Inhibitory Concentration 50; Leishmania donovani; Parasitic Sensitivity Tests; Phytochemicals; Plant Extracts; Plant Roots; Plasmodium falciparum; Salvia; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2018 |
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents.
Topics: Animals; Antiprotozoal Agents; Cell Line; Chagas Disease; Female; Humans; Imidazoles; Inhibitory Concentration 50; Leishmania donovani; Leishmaniasis, Visceral; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African | 2018 |
Methionine-Containing Rhabdopeptide/Xenortide-like Peptides from Heterologous Expression of the Biosynthetic Gene Cluster kj12ABC in Escherichia coli.
Topics: Amino Acids; Animals; Antineoplastic Agents; Antiparasitic Agents; Escherichia coli; Methionine; Multigene Family; Oligopeptides; Parasites; Rats; Xenorhabdus | 2018 |
Antiprotozoal Isoprenoids from Salvia hydrangea.
Topics: Animals; Antiprotozoal Agents; Cell Line; Leishmania donovani; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Rats; Salvia; Spectrum Analysis; Terpenes; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2018 |
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents.
Topics: Animals; Antiprotozoal Agents; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Drug Evaluation, Preclinical; Humans; Imidazoles; Parasitic Sensitivity Tests; Trypanosoma | 2019 |
Ealamines A-H, a Series of Naphthylisoquinolines with the Rare 7,8'-Coupling Site, from the Congolese Liana
Topics: Animals; Antineoplastic Agents, Phytogenic; Antiprotozoal Agents; Caryophyllales; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Leishmania; Molecular Structure; Naphthalenes; Pancreatic Neoplasms; Plant Components, Aerial; Plant Leaves; Plasmodium; Rats; Trypanosoma | 2019 |
A new chemotype with promise against Trypanosoma cruzi.
Topics: Animals; Chagas Disease; Humans; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2020 |
Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivatives.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Isothiocyanates; Leishmania donovani; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2020 |
Structure, Biosynthesis, and Bioactivity of Photoditritide from
Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Microbial Sensitivity Tests; Micrococcus luteus; Molecular Structure; Photorhabdus; Spectrum Analysis; Trypanosoma brucei rhodesiense | 2019 |
Spirombandakamine A
Topics: Alkaloids; Animals; Antiprotozoal Agents; Caryophyllales; Cell Line; Democratic Republic of the Congo; Isoquinolines; Molecular Structure; Phytochemicals; Plant Leaves; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense | 2021 |
Synthesis and Biological Evaluation of Natural-Product-Inspired, Aminoalkyl-Substituted 1-Benzopyrans as Novel Antiplasmodial Agents.
Topics: Alkylation; Animals; Antimalarials; Benzopyrans; Biological Products; Biomimetic Materials; Chemistry Techniques, Synthetic; Erythrocytes; Kinetics; Mice; Plasmodium; Structure-Activity Relationship | 2021 |
Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles.
Topics: Antiprotozoal Agents; Benzimidazoles; Cations; Dose-Response Relationship, Drug; Guanidine; Leishmania donovani; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2021 |
Anti-protozoal and anti-fungal evaluation of 3,5-disubstituted 1,2-dioxolanes.
Topics: Antifungal Agents; Antiprotozoal Agents; Aspergillus; Candida; Dioxolanes; Dose-Response Relationship, Drug; Leishmania; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium; Structure-Activity Relationship | 2021 |
Indole-Containing Pyrazino[2,1-
Topics: | 2022 |
Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Chloroquine; Disease Models, Animal; Drug Combinations; Female; Leishmania major; Leishmania mexicana; Leishmaniasis, Cutaneous; Mice; Mice, Inbred BALB C; Parasite Load; Parasitic Sensitivity Tests; Paromomycin; Phosphorylcholine | 2017 |