chloroquine has been researched along with methotrexate in 109 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (28.44) | 18.7374 |
| 1990's | 13 (11.93) | 18.2507 |
| 2000's | 29 (26.61) | 29.6817 |
| 2010's | 30 (27.52) | 24.3611 |
| 2020's | 6 (5.50) | 2.80 |
| Authors | Studies |
|---|---|
| Genther, CS; Smith, CS | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Caron, G; Ermondi, G; Lorenti, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Masseno, V; Muriithi, S; Nzila, A | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT | 1 |
| Fanburg, BL | 1 |
| Flenker, I; Ricken, D | 1 |
| Müller, AE; Thiele, HG | 1 |
| Norris, DA; Sams, WM; Weston, WL | 1 |
| Crossley, MJ; Hunneyball, IM; Spowage, M | 1 |
| Karger, T; Rau, R | 1 |
| Dugowson, CE; Gilliland, BC | 1 |
| Braunsteiner, H; Günther, R; Huber, C; Huber, H; Michlmayr, G | 1 |
| Lazar, M; Leopold, IH; Weiner, MJ | 1 |
| Kölle, G | 1 |
| Babaiants, RS; Shakhtmeĭster, II; Shelest, GV | 1 |
| Colombo, C; Ignarro, LJ | 1 |
| Braun, HJ | 1 |
| Pulgram, A; Weippl, G; Zimprich, H | 1 |
| Kerl, H; Klein, G; Sandhofer, M | 1 |
| Tronnier, H | 1 |
| Ankermann, H; Bauer, B; Klinger, W; Traeger, A | 1 |
| Rothermich, NO | 1 |
| Missmahl, HP | 2 |
| Kalbhen, DA; Lynen, J | 1 |
| Johnston, GS; Jones, AE | 1 |
| Kaulen-Becker, L | 1 |
| Burnham, TK; Fine, G; Lester, RS; Murray, K | 1 |
| Datko, LJ; Kassarich, J; Rosenthale, ME; Schneider, F | 1 |
| Belisario, JC; Kocsard, E; Kramer, H | 1 |
| Graeme, ML; John, M; Sigg, EB | 1 |
| Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF | 1 |
| Chu, BC; Howell, SB | 1 |
| Farewell, VT; Gladman, DD; Gough, J; Long, J; Mader, R | 1 |
| Albuquerque, E; Atra, E; Brandao, L; Ferraz, MB; Helfenstein, M; Pinheiro, GC; Pinheiro, GR; Rezende, C; Roimicher, L; Silva, SC | 1 |
| Albertioni, F; Beck, O; Eksborg, S; Peterson, C; Seideman, P | 1 |
| Braun, O; Kolarz, G; Popp, W; Ritschka, L; Scherak, O; Wottawa, A | 1 |
| Khraishi, MM; Singh, G | 1 |
| Hendrich, C; Siebert, WE | 1 |
| Menninger, H | 1 |
| Ali, AA; Beg, JA; Hussain, MA; Iqbal, MP; Mehboobali, N; Rahbar, MH | 1 |
| McNeil, J; Shabani, F; Tippett, L | 1 |
| Hansen, A; Jensen, T | 1 |
| Keysser, C; Keysser, M; Keyszer, G | 1 |
| Keysser, C; Keysser, G; Keysser, M | 1 |
| Kramer, MR; Yarmolovsky, A | 1 |
| Can, C; Dinc, A; Erdem, H; Pay, S; Simsek, I | 1 |
| Di Poi, E; Fabris, M; Ferraccioli, G; Mecchia, F | 1 |
| Konishi, M; Takahashi, K; Yoneda, K; Yoshimoto, E | 1 |
| Kellner, H; Schiemann, U | 1 |
| Gross, WL; Schnabel, A | 1 |
| Lasserson, T; Paramothayan, S; Walters, EH | 1 |
| Dolgova, LN; Noskov, SM; Polyakov, DP; Snigireva, AV; Somova, MA | 1 |
| SCHAIBLE, G | 1 |
| Agarwal, N; Gupta, AK; Jain, SK; Yadava, RK | 1 |
| Lotz, M; Quach, J; Seitz, M; Valbracht, J | 1 |
| Bersani-Amado, CA; Bracht, A; Caparroz-Assef, SM; Cuman, RK; Ishii-Iwamoto, EL; Kimura, E; Silva, MA | 1 |
| Cuneo, JA; Marcos, J; Marcos, JC; Rébora, ME | 1 |
| Lasserson, TJ; Paramothayan, S; Walters, EH | 1 |
| Tüting, T; Wenzel, J | 1 |
| Tłustochowicz, W | 1 |
| Madhok, R; Wu, O | 1 |
| Kimura, E; Oga, S; Pereira, RM | 1 |
| Adagu, I; Dar, O; Khan, MS | 1 |
| Gergely, P; Poór, G | 1 |
| Aguirre, V; Arriagada, S; Bertoglio, JC; Burgos, RA; Cáceres, DD; Calvo, M; Hancke, JL | 1 |
| Afif, N; Chatelus, E; Goetz, J; Lipsker, D; Sibilia, J; Sordet, C; Sparsa, L | 1 |
| Darmochwal-Kolarz, D; Dryglewska, M; Kolarz, B; Majdan, M | 1 |
| Bulut, V; Çolak, M; Flores-Arce, MF; Nazıroğlu, M; Önal, S | 1 |
| Farajzadegan, Z; Salesi, M | 1 |
| Ally, M; Anderson, R; Hodkinson, B; Meyer, PW; Musenge, E; Tikly, M | 1 |
| Alam, MN; Haq, SA; Hossain, M; Islam, MN; Rasker, JJ; Ten Klooster, PM | 1 |
| Bahrami, S; Callen, JP; Hazey, MA; Wilkerson, E | 1 |
| Ratner, M | 1 |
| Agostini, C; Battista, A; Coran, A; Giraudo, C; Polverosi, R; Pomerri, F; Russo, R | 1 |
| Dai, QD; Guan, TR; Song, XW; Tang, WJ; Wu, YJ; Zhang, Y | 1 |
| Castro, C; de la Hoz-Valle, J; Palomino, A; Sánchez, G; Santos-Moreno, PI; Villarreal, L | 1 |
| Ganne, P; Srinivasan, R | 1 |
| Antopolsky, M; Hagström, M; Kidron, H; Latonen, S; Manzanares, JA; Rimpelä, AK; Schmitt, M; Urtti, A | 1 |
| Machado-Alba, JE; Machado-Duque, ME; Ruiz, AF | 1 |
| Bananis, E; Chen, C; Curtis, JR; Fan, H; Hirose, T; Lindsey, S; Mendelsohn, AM; Nduaka, CI; Tanaka, Y; Valdez, H; Wang, L; Winthrop, KL; Yamaoka, K | 1 |
| Hagström, M; Kidron, H; Rimpelä, AK; Urtti, A | 1 |
| Bazzichi, L; Bianchino, L; Caporali, R; Nacci, F; Sinigaglia, L | 1 |
| Jamali, Z; Pirhadi, R; Pourahmad, J; Ramazani, M; Salimi, A; Yousefsani, BS | 1 |
| Hagström, M; Hellinen, L; Knuutila, H; Reinisalo, M; Ruponen, M; Urtti, A | 1 |
| Amiri, N; Baldwin, C; De Vera, MA; Rebić, N; Sayre, EC; Zusman, EZ | 1 |
| C Kapetanovic, M; Einarsson, JT; Geborek, P; Källmark, H; Nilsson, JÅ; Olofsson, T; Saxne, T | 1 |
| Bennett, C; Chen, S; Hannon, CW; Lima, HC; McCourt, C | 1 |
| Brice, N; Harrison, MJ; Scott, C | 1 |
| Fernando, D; Herath, T; Rajapakse, S; Rodrigo, C; Wickramarachchi, U | 1 |
24 review(s) available for chloroquine and methotrexate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drugs for the Treatment of Zika Virus Infection.
Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection | 2020 |
The treatment of sarcoidosis.
Topics: Adrenal Cortex Hormones; Chloroquine; Dose-Response Relationship, Drug; Humans; Methotrexate; Remission, Spontaneous; Sarcoidosis | 1979 |
Management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyclophosphamide; Drug Therapy, Combination; Felty Syndrome; Gold; Humans; Hydroxychloroquine; Immunosuppressive Agents; Leukapheresis; Lung Diseases; Lymphoid Tissue; Methotrexate; Penicillamine; Plasmapheresis; Radiotherapy; Rheumatic Diseases; Salicylates; Sjogren's Syndrome; Spinal Diseases; Vasculitis | 1986 |
[Treatment of psoriasis].
Topics: Adrenocorticotropic Hormone; Aminopterin; Chloroquine; Dexamethasone; Diet Therapy; Flumethasone; Glucocorticoids; Humans; Methotrexate; Prednisolone; Prodigiosin; Psoriasis; Pyrogens; Triamcinolone; Vitamins | 1972 |
[Clinical picture, diagnostics and therapy of amyloidoses].
Topics: Adrenal Gland Diseases; Amyloidosis; Biopsy; Chloroquine; Chronic Disease; Gastrointestinal Diseases; Humans; Infections; Kidney Diseases; Liver Diseases; Methotrexate; Neoplasms; Pancreatic Diseases; Prognosis; Splenic Diseases | 1972 |
An updated look at antirheumatic drugs.
Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis; Azathioprine; Chloroquine; Cyclophosphamide; Glucocorticoids; Humans; Immunosuppressive Agents; Indomethacin; Methotrexate; Nitrogen Mustard Compounds; Rheumatic Diseases; Salicylates | 1967 |
[Amyloidosis in chronic rheumatic diseases].
Topics: Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Biopsy; Chloroquine; Chronic Disease; Collagen Diseases; Felty Syndrome; Female; Humans; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Proteinuria; Psoriasis; Rectum; Rheumatic Diseases; Sjogren's Syndrome; Spondylitis, Ankylosing | 1968 |
Problems of antiarthritic therapy in the elderly.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Chloroquine; Female; Gold; Gout; Humans; Male; Methotrexate; Middle Aged; Osteoarthritis; Penicillamine; Probenecid | 1984 |
The role of anti-malarials in rheumatoid arthritis--the American experience.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Therapy, Combination; Humans; Hydroxychloroquine; Liver; Methotrexate; United States | 1996 |
[Basic therapeutic combination therapy in chronic polyarthritis: an overview].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Clinical Trials as Topic; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Methotrexate; Treatment Outcome | 1998 |
[Combination therapy of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Azathioprine; Chloroquine; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Methotrexate; Penicillamine; Randomized Controlled Trials as Topic; Sulfasalazine | 1998 |
[Treatment of sarcoidosis--1999].
Topics: Adrenal Cortex Hormones; Chloroquine; Humans; Lung Diseases; Methotrexate; Sarcoidosis | 1999 |
[Non-steroid therapy for sarcoidosis].
Topics: Anti-Inflammatory Agents; Antimalarials; Azathioprine; Chlorambucil; Chloroquine; Cyclophosphamide; Cyclosporine; Humans; Methotrexate; Sarcoidosis; Steroids | 2002 |
[Gastrointestinal side effects in the therapy of rheumatologic diseases].
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Etanercept; Gastrointestinal Diseases; Glucocorticoids; Humans; Hydroxychloroquine; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Rheumatic Diseases; Stomach Ulcer; Sulfasalazine; Tumor Necrosis Factor-alpha | 2002 |
Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis.
Topics: Antineoplastic Agents; Chloroquine; Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Randomized Controlled Trials as Topic; Sarcoidosis, Pulmonary | 2003 |
Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis.
Topics: Antineoplastic Agents; Chloroquine; Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Pentoxifylline; Prednisone; Randomized Controlled Trials as Topic; Sarcoidosis, Pulmonary | 2006 |
Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches.
Topics: Antimalarials; Autoantibodies; Chemokines; Chloroquine; Cytokines; Humans; Immunosuppressive Agents; Inflammation Mediators; Interferon Type I; Lupus Erythematosus, Cutaneous; Methotrexate; Models, Biological | 2007 |
[Rational therapeutic approach in rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Isoxazoles; Joint Prosthesis; Leflunomide; Methotrexate; Prostheses and Implants; Sulfasalazine | 2006 |
Systemic lupus erythematosus.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Chloroquine; Humans; Incidence; Lupus Erythematosus, Systemic; Methotrexate; Prevalence; Prognosis; Randomized Controlled Trials as Topic | 2007 |
[New ways in the management of rheumatoid arthritis in Hungary].
Topics: Abatacept; Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Rheumatoid; Autoimmunity; Azathioprine; Chloroquine; Cyclophosphamide; Cyclosporine; Diagnosis, Differential; Early Diagnosis; Etanercept; Humans; Hungary; Immunoconjugates; Immunoglobulin G; Immunologic Factors; Immunosuppressive Agents; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Prognosis; Receptors, Tumor Necrosis Factor; Rituximab; Sulfasalazine; Tumor Necrosis Factor-alpha | 2007 |
Interventions for cutaneous disease in systemic lupus erythematosus.
Topics: Age of Onset; Azathioprine; Bias; Biological Factors; Chloroquine; Cosmetic Techniques; Cyclosporine; Dermatologic Agents; Exanthema; Female; Humans; Hydroxychloroquine; Immunosuppressive Agents; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Male; Medicine, Chinese Traditional; Methotrexate; Placebos; Quality of Life; Randomized Controlled Trials as Topic; Skin Diseases; Symptom Flare Up | 2021 |
Clinical Features of HIV Arthropathy in Children: A Case Series and Literature Review.
Topics: Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; CD4 Lymphocyte Count; Child; Chloroquine; Comorbidity; Female; Glucocorticoids; HIV; HIV Infections; Humans; Male; Methotrexate; Prednisone; Prevalence; Retrospective Studies; South Africa; Treatment Outcome | 2021 |
Treatment of chikungunya-associated joint pain: a systematic review of controlled clinical trials.
Topics: Anti-Inflammatory Agents; Arthralgia; Chikungunya Fever; Chloroquine; Humans; Hydroxychloroquine; Methotrexate; Observational Studies as Topic; Retrospective Studies; Ribavirin | 2022 |
10 trial(s) available for chloroquine and methotrexate
| Article | Year |
|---|---|
Combination therapy with methotrexate and chloroquine in rheumatoid arthritis. A multicenter randomized placebo-controlled trial.
Topics: Adult; Arthritis, Rheumatoid; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Treatment Outcome | 1994 |
Bronchoalveolar lavage and lung biopsy in rheumatoid arthritis. In vivo effects of disease modifying antirheumatic drugs.
Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Bronchoalveolar Lavage Fluid; Chloroquine; Humans; Lung; Lymphocyte Subsets; Methotrexate; Middle Aged; Organogold Compounds; Penicillamine | 1993 |
Efficacy and safety of a combination therapy of methotrexate, chloroquine and cyclophosphamide in patients with refractory rheumatoid arthritis: results of an observational study with matched-pair analysis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cohort Studies; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Joints; Male; Matched-Pair Analysis; Methotrexate; Middle Aged; Treatment Outcome | 1999 |
The use of homeopathic preparation Vozraston in the therapy of patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Humans; Immunosuppressive Agents; Materia Medica; Methotrexate; Pain; Treatment Outcome | 2003 |
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; Double-Blind Method; Drug Therapy, Combination; Female; Glutathione; Humans; Methotrexate; Middle Aged; Phytotherapy; Placebos; Plant Extracts; Plant Leaves; Prednisone; Prospective Studies; Radiography; Severity of Illness Index; Young Adult | 2009 |
Effects of different medical treatments on serum copper, selenium and zinc levels in patients with rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chloroquine; Copper; Female; Humans; Male; Methotrexate; Middle Aged; Selenium; Sulfasalazine; Zinc | 2011 |
Efficacy of vitamin D in patients with active rheumatoid arthritis receiving methotrexate therapy.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Prednisone; Severity of Illness Index; Treatment Outcome; Vitamin D | 2012 |
Efficacy and safety of methotrexate in articular and cutaneous manifestations of systemic lupus erythematosus.
Topics: Adolescent; Adult; Arthralgia; Arthritis; Bangladesh; Blood Sedimentation; Chloroquine; Female; Humans; Immunosuppressive Agents; Joints; Lupus Erythematosus, Systemic; Male; Methotrexate; Pain Measurement; Prospective Studies; Severity of Illness Index; Skin; Surveys and Questionnaires; Time Factors; Treatment Outcome; Young Adult | 2012 |
[Treatment of severe active systemic lupus erythematosus by PMC therapy combined langchuang fuzheng jiedu capsule: a clinical observation].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Chloroquine; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Integrative Medicine; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Phytotherapy; Prednisone; Young Adult | 2013 |
Subcutaneous tocilizumab alone or with a csDMARD in rheumatoid arthritis patients: subanalysis of Italian data from a multicenter phase IIIb/IV trial.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Injections, Subcutaneous; Leflunomide; Male; Methotrexate; Middle Aged; Sulfasalazine; Treatment Outcome | 2019 |
75 other study(ies) available for chloroquine and methotrexate
| Article | Year |
|---|---|
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Acid Antagonists; Malaria; Mice; Plasmodium berghei; Triazines | 1977 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction.
Topics: Chromatography, Affinity; Hydrogen-Ion Concentration; Ions; Models, Molecular; Molecular Conformation; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin, Bovine; Ultracentrifugation | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid.
Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
[Therapy of systemic lupus erythematosus and of pseudo-le-syndrome].
Topics: Aged; Azathioprine; Chloroquine; Cyclophosphamide; Diagnosis, Differential; Female; Glucocorticoids; Humans; Indomethacin; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Phenylbutazone; Prednisone; Salicylates; Sex Factors; Syndrome | 1978 |
[On the mode of action of antirheumatic drugs (author's transl)].
Topics: Antibiotics, Antineoplastic; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Gold; Gold Sodium Thiosulfate; Humans; Methotrexate; Microsomes, Liver; Penicillamine | 1976 |
The effect of immunosuppressive and anti-inflammatory drugs on monocyte function in vitro.
Topics: Anti-Inflammatory Agents; Blood Bactericidal Activity; Chemotaxis; Chloroquine; Cyclophosphamide; Dapsone; Dexamethasone; Humans; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Monocytes; Phagocytosis; Sulfapyridine; Vinblastine | 1977 |
Studies on the effects of pharmacological agents on antigen-induced arthritis in BALB/c mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Arthritis; Arthritis, Experimental; Azathioprine; Chloroquine; Methotrexate; Mice; Mice, Inbred BALB C; Penicillamine; Sulfapyridine; Sulfasalazine; Tiopronin | 1987 |
[Treatment of chronic polyarthritis with low-dose methotrexate].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Evaluation; Drug Therapy, Combination; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Penicillamine; Time Factors | 1988 |
[DNA-synthesizing lymphocytes in the blood of patients with disseminated lupus erythematosus, rheumatoid arthritis, and panarteritis nodosa (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Chloroquine; DNA; Female; Gold; Humans; Indomethacin; Leukocyte Count; Lupus Erythematosus, Systemic; Lymphocytes; Male; Methotrexate; Methylprednisolone; Middle Aged; Penicillamine; Polyarteritis Nodosa | 1973 |
Treatment of uveitis with methotrexate.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Alopecia; Anti-Bacterial Agents; Child; Chloroquine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Indomethacin; Male; Methotrexate; Middle Aged; Nausea; Ophthalmia, Sympathetic; Pyrimethamine; Stomatitis; Uveitis; Vision, Ocular; Vomiting | 1969 |
[Long term therapy of rheumatoid arthritis in children].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chloroquine; Gold; Humans; Indomethacin; Long-Term Care; Manipulation, Orthopedic; Methotrexate; Phenylbutazone; Physical Therapy Modalities; Pyrazoles; Salicylates; Synovectomy; Uveitis, Anterior | 1970 |
Enzyme release from guinea-pig polymorphonuclear leucocyte lysosomes inhibited in vitro by anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Chloroquine; Cyclophosphamide; Depression, Chemical; Flufenamic Acid; Galactosidases; Glucuronidase; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Indomethacin; Leukocytes; Lysosomes; Methotrexate; Phenylbutazone; Sulfatases | 1972 |
[Lupus erythematosus in childhood].
Topics: Anemia, Hemolytic, Autoimmune; Autoantibodies; Azathioprine; Child; Chloroquine; Female; Humans; Lupus Erythematosus, Systemic; Methotrexate; Prednisone | 1973 |
[Treatment of "collagen and autoimmune" diseases (author's transl)].
Topics: Adolescent; Adult; Aminobenzoates; Azathioprine; Chloroquine; Cyclophosphamide; Dermatomyositis; Dextrans; Female; Humans; Indomethacin; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Norethindrone; Penicillamine; Pregnanes; Scleroderma, Localized; Scleroderma, Systemic | 1973 |
[Therapy of mycosis fungoides].
Topics: Aspirin; Chloroquine; Cyclophosphamide; Humans; Methotrexate; Mycosis Fungoides; Prednisone; Sunlight; Ultraviolet Rays; Vinblastine | 1973 |
The influence of alkylants, antimetabolites and chloroquine on oxydative biotransformation reactions and on the excretion of ascorbic acid in the rat.
Topics: Alkylating Agents; Animals; Antimetabolites; Ascorbic Acid; Biotransformation; Chloroquine; Cyclophosphamide; Liver; Male; Mercaptopurine; Methotrexate; Oxidation-Reduction; Rats; Triazines; Uracil | 1973 |
[Effect of some anti-inflammatory drugs on the ATP-content and cell proliferation of neoplastic mast cells in vitro].
Topics: Adenosine Triphosphate; Amides; Aminopyrine; Anti-Inflammatory Agents; Aspirin; Benzimidazoles; Benzoates; Cell Division; Chloroquine; Culture Techniques; Depression, Chemical; Dinitrophenols; Indomethacin; Mast-Cell Sarcoma; Methotrexate; Naphthalenes; ortho-Aminobenzoates; Oxyphenbutazone; Phenylbutazone; Salicylamides; Sodium Salicylate; Stimulation, Chemical | 1968 |
Sequential liver scanning.
Topics: Adult; Breast Neoplasms; Chloroquine; Colonic Neoplasms; Dactinomycin; Emetine; Estrogens; Female; Fluorouracil; Gold Colloid, Radioactive; Humans; Liver Abscess, Amebic; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Radionuclide Imaging; Thiotepa | 1969 |
[Pityriasis rubra pilaris].
Topics: Adult; Chloroquine; Female; Humans; Male; Methotrexate; Middle Aged; Pityriasis Rubra Pilaris; Vitamin A | 1972 |
Immunologic concepts of light reactions in lupus erythematosus and polymorphous light eruptions. I. The mechanism of action of hydroxychloroquine.
Topics: Antibodies, Antinuclear; Autoantibodies; Chloroquine; DNA; Erythema; Humans; Hydralazine; Hydroxychloroquine; Injections, Intradermal; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Methotrexate; Methylprednisolone; Prednisone; Protein Binding; Skin Manifestations; Ultraviolet Rays | 1967 |
Chemotherapy of experimental allergic encephalomyelitis (EAE).
Topics: Allopurinol; Aminocaproates; Analgesics; Animals; Antineoplastic Agents; Azathioprine; Body Weight; Chloroquine; Colchicine; Cortisone; Cyclophosphamide; Cyproheptadine; Diazoxide; Dimethyl Sulfoxide; Encephalomyelitis, Autoimmune, Experimental; Hydrocortisone; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Methyldopa; Nialamide; Oils; Organ Size; Rats; Strychnine; Talc; Thalidomide; Thioguanine; Thiomalates | 1969 |
[Amyloidosis in ankylosing spondylitis].
Topics: Amyloidosis; Biopsy; Chloroquine; Diagnosis, Differential; Female; Humans; Kidney Failure, Chronic; Methotrexate; Middle Aged; Prognosis; Proteinuria; Rectum; Spondylitis, Ankylosing | 1969 |
[Excessive destruction of tissues caused by topical cytotoxic therapy].
Topics: Aged; Benzocycloheptenes; Carcinoma, Basal Cell; Chloroquine; Dermatitis; Facial Neoplasms; Female; Humans; Male; Methotrexate; Middle Aged; Necrosis; Skin Neoplasms; Skin Ulcer | 1970 |
Induction of periarthritis by oral administration of 6-sulfanilamidoindazole and its treatment in rats.
Topics: Animals; Aspirin; Chloroquine; Cloxacillin; Hydralazine; Hydrocortisone; Indomethacin; Male; Mercaptopurine; Methotrexate; Morphine; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Periarthritis; Phenylbutazone; Rats; Sulfinpyrazone; Sulfonamides | 1967 |
Differential toxicity of carrier-bound methotrexate toward human lymphocytes, marrow and tumor cells.
Topics: Astrocytoma; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Chloroquine; Deoxyuridine; Humans; In Vitro Techniques; Lymphocytes; Methotrexate; Neoplasms, Experimental | 1981 |
Does injectable gold retard radiologic evidence of joint damage in psoriatic arthritis?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Case-Control Studies; Chloroquine; Female; Humans; Male; Methotrexate; Middle Aged; Organogold Compounds; Radiography; Steroids | 1995 |
Chloroquine reduces the bioavailability of methotrexate in patients with rheumatoid arthritis. A possible mechanism of reduced hepatotoxicity.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biological Availability; Chloroquine; Humans; Methotrexate; Middle Aged | 1994 |
Photodynamic therapy for rheumatoid arthritis?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Chi-Square Distribution; Chloroquine; Fibroblasts; Humans; Laser Therapy; Methotrexate; Photochemotherapy; Piroxicam; Sclerosing Solutions; Sodium Morrhuate | 1997 |
Methotrexate in rheumatoid arthritis: a 2 year experience at a university hospital in Pakistan.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Therapy, Combination; Female; Follow-Up Studies; Gold; Hospitals, University; Humans; Male; Methotrexate; Middle Aged; Penicillamine; Retrospective Studies; Sulfasalazine; Treatment Outcome | 1998 |
The oxidative inactivation of tissue inhibitor of metalloproteinase-1 (TIMP-1) by hypochlorous acid (HOCI) is suppressed by anti-rheumatic drugs.
Topics: Animals; Antioxidants; Antirheumatic Agents; Auranofin; Aurothioglucose; Cell Line; Chlorocebus aethiops; Chloroquine; Collagenases; Gold Sodium Thiomalate; Humans; Hypochlorous Acid; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Methotrexate; Neutrophils; Oxidants; Oxidation-Reduction; Penicillamine; Peptide Fragments; Peroxidase; Recombinant Fusion Proteins; Respiratory Burst; Structure-Activity Relationship; Taurine; Tissue Inhibitor of Metalloproteinase-1 | 1998 |
Long-term application of disease modifying antirheumatic drugs (DMARD). A single-center, observational study of 1681 patients with rheumatoid arthritis (RA).
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Long-Term Care; Male; Methotrexate; Middle Aged; Organogold Compounds; Penicillamine; Sulfasalazine; Treatment Outcome | 1999 |
Sulfasalazine-induced angioimmunoblastic lymphadenopathy developing in a patient with juvenile chronic arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Chloroquine; Humans; Immunoblastic Lymphadenopathy; Lymph Nodes; Male; Methotrexate; Methylprednisolone; Sulfasalazine | 2000 |
Anticardiolipin antibodies in rheumatoid patients treated with etanercept or conventional combination therapy: direct and indirect evidence for a possible association with infections.
Topics: Adolescent; Adult; Aged; Antibodies, Anticardiolipin; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Rheumatoid; Child; Child, Preschool; Chloroquine; Cyclosporine; Drug Combinations; Etanercept; Humans; Immunoglobulin G; Immunoglobulin M; Infant; Infant, Newborn; Methotrexate; Middle Aged; Receptors, Tumor Necrosis Factor; Staphylococcal Infections; Staphylococcus aureus | 2002 |
[Evidence-based treatment of methotrexate-resistant rheumatoid arthritis. Combinations of conventional disease-modifying antirheumatic agents].
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cyclosporine; Drug Resistance; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydroxychloroquine; Immunosuppressive Agents; Isoxazoles; Leflunomide; Methotrexate; Placebos; Prednisolone; Randomized Controlled Trials as Topic; Sulfasalazine; Time Factors | 2003 |
[Management of amebic dysentery and its complications with resotren comp].
Topics: Amebiasis; Antineoplastic Combined Chemotherapy Protocols; Chloroquine; Cyclophosphamide; Dysentery, Amebic; Humans; Hydroxyquinolines; Iodoquinol; Methotrexate; Prednisone; Vincristine | 1956 |
Quadriparesis in a young female suffering from rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Celecoxib; Cervical Vertebrae; Chloroquine; Cyclooxygenase Inhibitors; Female; Humans; Magnetic Resonance Imaging; Methotrexate; Pyrazoles; Quadriplegia; Radiography; Sulfonamides; Treatment Failure | 2003 |
Gold sodium thiomalate and chloroquine inhibit cytokine production in monocytic THP-1 cells through distinct transcriptional and posttranslational mechanisms.
Topics: Antirheumatic Agents; Caspase 1; Cell Line; Chloroquine; Cytokines; Gold Sodium Thiomalate; Humans; Interleukin-1; Lipopolysaccharides; MAP Kinase Signaling System; Methotrexate; Mitogen-Activated Protein Kinases; Monocytes; Phosphorylation; Protein Processing, Post-Translational; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2003 |
Efficiency of combined methotrexate/chloroquine therapy in adjuvant-induced arthritis.
Topics: Acid Phosphatase; Alanine Transaminase; Alkaline Phosphatase; Animals; Arthritis, Experimental; Aspartate Aminotransferases; Body Weight; Chloroquine; Drug Therapy, Combination; Liver; Male; Methotrexate; Rats | 2005 |
Kartagener syndrome and rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Therapy, Combination; Female; Humans; Kartagener Syndrome; Methotrexate; Tomography, X-Ray Computed | 2006 |
Comparative study of the pharmacokinetics of MTX in juvenile idiopathic arthritis patients receiving long-term MTX monotherapy or MTX plus chloroquine.
Topics: Adolescent; Adult; Antirheumatic Agents; Area Under Curve; Arthritis, Juvenile; Child; Chloroquine; Drug Therapy, Combination; Female; Humans; Male; Methotrexate | 2007 |
The potential use of methotrexate in the treatment of falciparum malaria: in vitro assays against sensitive and multidrug-resistant falciparum strains.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Humans; Hypoxanthine; Malaria, Falciparum; Methotrexate; Nucleic Acid Synthesis Inhibitors; Parasitic Sensitivity Tests; Plasmodium falciparum; Tritium | 2008 |
Jessner-Kanof disease induced by leflunomide: a dermal variant of cutaneous lupus?
Topics: Antibodies, Antinuclear; Antirheumatic Agents; Chloroquine; Female; Gold; Humans; Interleukin 1 Receptor Antagonist Protein; Isoxazoles; Leflunomide; Lupus Erythematosus, Cutaneous; Methotrexate; Middle Aged; Treatment Outcome | 2011 |
Antibodies against cyclic citrullinated peptide don't decrease after 6 months of infliximab treatment in refractory rheumatoid arthritis.
Topics: Adult; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Immunoglobulin M; Immunosuppressive Agents; Infliximab; Male; Methotrexate; Middle Aged; Peptides, Cyclic; Rheumatoid Factor; Young Adult | 2011 |
Response to traditional disease-modifying anti-rheumatic drugs in indigent South Africans with early rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Poverty; Prednisone; Radiography; Severity of Illness Index; South Africa; Sulfasalazine; Treatment Outcome; Uncompensated Care | 2012 |
Golimumab-exacerbated subacute cutaneous lupus erythematosus.
Topics: Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antirheumatic Agents; Chloroquine; Desonide; Drug Eruptions; Female; Humans; Lupus Erythematosus, Cutaneous; Methotrexate; Prednisone | 2012 |
Amgen best-seller challenged by generics.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biosimilar Pharmaceuticals; Chloroquine; Clinical Trials as Topic; Comparative Effectiveness Research; Drug Industry; Drugs, Generic; Etanercept; Humans; Immunoglobulin G; Methotrexate; Receptors, Tumor Necrosis Factor; Sulfasalazine; Therapeutic Equivalency | 2013 |
Typical and atypical pattern of pulmonary sarcoidosis at high-resolution CT: relation to clinical evolution and therapeutic procedures.
Topics: Adult; Aged; Antirheumatic Agents; Chloroquine; Female; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Sarcoidosis, Pulmonary; Steroids; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
Treatment of rheumatoid arthritis with methotrexate alone and in combination with other conventional DMARDs using the T2T strategy. A cohort study.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cohort Studies; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Prednisolone; Retrospective Studies; Sulfasalazine; Treatment Outcome; Young Adult | 2015 |
Chloroquine retinopathy.
Topics: Antirheumatic Agents; Chloroquine; Drug Substitution; Electroretinography; Humans; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Optic Atrophy; Retinal Diseases; Visual Fields | 2015 |
Drug Distribution to Retinal Pigment Epithelium: Studies on Melanin Binding, Cellular Kinetics, and Single Photon Emission Computed Tomography/Computed Tomography Imaging.
Topics: Animals; Cells, Cultured; Chloroquine; Eye; Hydrogen-Ion Concentration; Iodine Radioisotopes; Kinetics; Melanins; Methotrexate; Nadolol; Protein Binding; Rats; Retinal Pigment Epithelium; Single Photon Emission Computed Tomography Computed Tomography; Swine; Timolol | 2016 |
Effectiveness of treatment with biologic- and disease-modifying antirheumatic drugs in rheumatoid arthritis patients in Colombia.
Topics: Abatacept; Adolescent; Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Child; Child, Preschool; Chloroquine; Cohort Studies; Colombia; Etanercept; Female; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Retrospective Studies; Severity of Illness Index; Young Adult | 2016 |
Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Clinical Trials as Topic; Databases, Factual; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucocorticoids; Herpes Zoster; Humans; Incidence; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Multivariate Analysis; Piperidines; Proportional Hazards Models; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Risk Factors | 2017 |
Melanin targeting for intracellular drug delivery: Quantification of bound and free drug in retinal pigment epithelial cells.
Topics: Animals; Biological Transport; Cell Line; Chloroquine; Diclofenac; Epithelial Cells; Humans; Melanins; Methotrexate; Molecular Targeted Therapy; Propranolol; Retinal Pigment Epithelium; Swine; Timolol | 2018 |
Mitochondrial and lysosomal protective agents ameliorate cytotoxicity and oxidative stress induced by cyclophosphamide and methotrexate in human blood lymphocytes.
Topics: Adolescent; Adult; Antineoplastic Agents; Butylated Hydroxytoluene; Cell Survival; Cells, Cultured; Chloroquine; Cyclophosphamide; Cyclosporine; Glutathione; Humans; Immunosuppressive Agents; Lymphocytes; Lysosomes; Methotrexate; Mitochondria; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Young Adult | 2019 |
Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model.
Topics: Animals; Biological Transport; Cell Line; Chloroquine; Diclofenac; Humans; Melanins; Melanosomes; Methotrexate; Phagocytosis; Pigmentation; Propranolol; Retina; Retinal Pigment Epithelium; Retinal Pigments; Swine | 2019 |
Perinatal use and discontinuation of disease-modifying anti-rheumatic drugs and biologics in women with rheumatoid arthritis: a cohort study.
Topics: Abatacept; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Biological Products; British Columbia; Chloroquine; Cohort Studies; Cyclophosphamide; Cyclosporine; Deprescriptions; Female; Glucocorticoids; Gold Compounds; Humans; Hydroxychloroquine; Interleukin 1 Receptor Antagonist Protein; Leflunomide; Logistic Models; Maternal Age; Methotrexate; Mycophenolic Acid; Odds Ratio; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, First; Rheumatology; Rituximab; Sulfasalazine; Tumor Necrosis Factor Inhibitors | 2020 |
Sustained Remission in Patients With Rheumatoid Arthritis Receiving Triple Therapy Compared to Biologic Therapy: A Swedish Nationwide Register Study.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Chloroquine; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Male; Methotrexate; Middle Aged; Odds Ratio; Registries; Sulfasalazine; Sweden; Treatment Outcome; Tumor Necrosis Factor Inhibitors | 2021 |