chloroquine and mercaptopurine

chloroquine has been researched along with mercaptopurine in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (61.29)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (16.13)	29.6817
2010's	7 (22.58)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Norris, DA; Sams, WM; Weston, WL	1
Kim, DN; Kwak, YS; Lee, KT	1
Mukhtar, H; Murti, CR; Sahib, MK	1
Dioguardi, N	1
Frearson, PM; Williams, DC	1
Mukhtar, H; Murti, CR	1
Ankermann, H; Bauer, B; Klinger, W; Traeger, A	1
Kelly, MR; Quadracci, LJ; Scribner, BH; Striker, GE	1
Ota, K	1
Brass, H; Heintz, R; Lapp, H	1
Robinson, BL; Warhurst, DC	1
Howells, RE; Peters, W; Robinson, BL; Warhurst, DC	1
Datko, LJ; Kassarich, J; Rosenthale, ME; Schneider, F	1
L'age-Stehr, J; Thiel, N; Wacker, A	1
Bihari, M; Grossman, BJ	1
Graeme, ML; John, M; Sigg, EB	1
PETRANYI, G	1
CHEN, CJ; CHENG, WF; KAO, NC; SUN, TJ; TSAO, KH; WANG, YC	1
HAVRE, DC	1
Abramo, C; Coimbra, ES; Corrales, RC; Da Silva, AD; de Souza, NB; Pinheiro, LS	1

Reviews

2 review(s) available for chloroquine and mercaptopurine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Multiple combination therapy in cancer chemotherapy in Japan. Gan, 1969, Volume: 60, Issue:3 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chloroquine; Cyclophosphamide; Cytarabine; Drug Synergism; Fluorouracil; Humans; Japan; Leukemia; Lymphoma; Mercaptopurine; Mitomycins; Neoplasms; Podophyllin; Prednisolone; Thiotepa; Vincristine; Vitamin K 1	1969

Other Studies

29 other study(ies) available for chloroquine and mercaptopurine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
The effect of immunosuppressive and anti-inflammatory drugs on monocyte function in vitro. The Journal of laboratory and clinical medicine, 1977, Volume: 90, Issue:3 Topics: Anti-Inflammatory Agents; Blood Bactericidal Activity; Chemotaxis; Chloroquine; Cyclophosphamide; Dapsone; Dexamethasone; Humans; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Monocytes; Phagocytosis; Sulfapyridine; Vinblastine	1977
Study of drugs affecting cholesterol-induced atherosclerosis in rabbits. Advances in experimental medicine and biology, 1976, Volume: 67, Issue:00 Topics: Animals; Arteriosclerosis; Aspirin; Chloroquine; Cholesterol, Dietary; Clomipramine; Hydroxyurea; Male; Mercaptopurine; Pharmacology; Pyridinolcarbamate; Rabbits; Sodium Dodecyl Sulfate	1976
Stabilization of rat liver tyrosine aminotransferase by drugs. Indian journal of biochemistry & biophysics, 1973, Volume: 10, Issue:1 Topics: Animals; Chloroquine; Drug Stability; Enzyme Induction; Liver; Male; Mercaptopurine; Phenacetin; Protein Biosynthesis; Rats; Stimulation, Chemical; Tetracycline; Tyrosine; Tyrosine Transaminase	1973
[The treatment of chronic hepatitis (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1974, Mar-29, Volume: 116, Issue:13 Topics: Adrenal Cortex Hormones; Antimetabolites; Azathioprine; Chloroquine; Chronic Disease; Hepatitis; Humans; Immobilization; Immunosuppression Therapy; Immunosuppressive Agents; Liver Function Tests; Medication Errors; Mercaptopurine; Recurrence; Rest	1974
The inhibition of 3-alpha-hydroxy steroid-activated nicotinamide-adenine dinucleotide (phosphate) transhydrogenase by some antimetabolic compounds. The Biochemical journal, 1964, Volume: 91, Issue:1 Topics: Androsterone; Animals; Antimetabolites; Chloroquine; Enzymes; Estradiol; In Vitro Techniques; Liver; Male; Mercaptopurine; NADP; Oxidoreductases; Purines; Rats; Uracil	1964
Induction of rat liver tyrosine aminotransferase by pharmacologically unrelated drugs. Indian journal of biochemistry, 1971, Volume: 8, Issue:2 Topics: Animals; Azaguanine; Chloroquine; Chlorpromazine; Enzyme Induction; Liver; Mercaptopurine; Phenacetin; Rats; Tetracycline; Tyrosine Transaminase	1971
The influence of alkylants, antimetabolites and chloroquine on oxydative biotransformation reactions and on the excretion of ascorbic acid in the rat. Acta biologica et medica Germanica, 1973, Volume: 30, Issue:3 Topics: Alkylating Agents; Animals; Antimetabolites; Ascorbic Acid; Biotransformation; Chloroquine; Cyclophosphamide; Liver; Male; Mercaptopurine; Methotrexate; Oxidation-Reduction; Rats; Triazines; Uracil	1973
The course of lupus nephritis: a clinical-pathological correlation of fifty patients. Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 2, Issue:0 Topics: Adolescent; Adult; Azathioprine; Basement Membrane; Biopsy; Chloroquine; Cyclophosphamide; Female; Follow-Up Studies; Glomerulonephritis; Glucocorticoids; Humans; Hyperplasia; Kidney Glomerulus; Lupus Erythematosus, Systemic; Male; Mercaptopurine; Nephritis; Prednisolone	1973
[Long term treatment of chronic glomerulonephritis, clinical course and results of renal biopsies]. Archiv fur klinische Medizin, 1969, Volume: 216, Issue:4 Topics: Acetates; Adolescent; Adult; Azathioprine; Biopsy; Blood Pressure; Chloroquine; Female; Glomerulonephritis; Hematuria; Humans; Inulin; Kidney Function Tests; Kidney Glomerulus; Long-Term Care; Male; Mercaptopurine; Middle Aged; Potassium; Prednisolone; Prednisone; Proteinuria; Testosterone; Urea	1969
Cytotoxic agents and haemozoin pigment in malaria parasites (Plasmodium berghei). Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Jul-08, Volume: 10, Issue:13 Topics: Animals; Antineoplastic Agents; Azaserine; Chloramphenicol; Chloroquine; Cycloheximide; Cytoplasm; Dactinomycin; Injections, Intraperitoneal; Malaria; Male; Mercaptopurine; Mice; Mitomycins; Nucleic Acids; Pigments, Biological; Plasmodium; Protein Biosynthesis; Puromycin; Streptomycin; Tetracycline; Uracil	1971
The effect of cytotoxic agents on autophagic vacuole formation in chloroquine-treated malaria parasites (Plasmodium berghei). Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Jul-08, Volume: 10, Issue:13 Topics: Animals; Antineoplastic Agents; Azaserine; Chloroquine; Colchicine; Cycloheximide; Cytoplasm; Dactinomycin; Malaria; Mercaptopurine; Mice; Mitomycins; Nucleic Acids; Pigments, Biological; Plasmodium; Protein Biosynthesis; Ribosomes; Uracil	1971
Chemotherapy of experimental allergic encephalomyelitis (EAE). Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 179, Issue:2 Topics: Allopurinol; Aminocaproates; Analgesics; Animals; Antineoplastic Agents; Azathioprine; Body Weight; Chloroquine; Colchicine; Cortisone; Cyclophosphamide; Cyproheptadine; Diazoxide; Dimethyl Sulfoxide; Encephalomyelitis, Autoimmune, Experimental; Hydrocortisone; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Methyldopa; Nialamide; Oils; Organ Size; Rats; Strychnine; Talc; Thalidomide; Thioguanine; Thiomalates	1969
[Studies on the influence of protein synthesis inhibitors on the formation of antibodies]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1967, Volume: 348, Issue:11 Topics: Animals; Anti-Infective Agents; Antibody Formation; Antimetabolites; Chloroquine; Dactinomycin; Depression, Chemical; Hemolysin Proteins; Hemolysis; Immunosuppressive Agents; In Vitro Techniques; Mercaptopurine; Mice; Nucleosides; Penicillamine; Protein Biosynthesis; Quinolines; Spleen; Uracil	1967
Posterior subcapsular cataracts. Related to long-term corticosteroid treatment in children. American journal of diseases of children (1960), 1968, Volume: 116, Issue:6 Topics: Adolescent; Arthritis, Juvenile; Cataract; Child; Child, Preschool; Chloroquine; Colitis, Ulcerative; Crohn Disease; Dermatomyositis; Female; Humans; Infant; Lupus Erythematosus, Systemic; Male; Mercaptopurine; Nephrosis; Prednisolone; Purpura	1968
Induction of periarthritis by oral administration of 6-sulfanilamidoindazole and its treatment in rats. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1 Topics: Animals; Aspirin; Chloroquine; Cloxacillin; Hydralazine; Hydrocortisone; Indomethacin; Male; Mercaptopurine; Methotrexate; Morphine; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Periarthritis; Phenylbutazone; Rats; Sulfinpyrazone; Sulfonamides	1967
[TREATMENT OF LUPUS-NEPHROPATHIES WITH 6-MERCAPTOPURINE]. Orvosi hetilap, 1964, Jan-19, Volume: 105 Topics: Albuminuria; Chloroquine; Diuretics; Edema; Glomerulonephritis; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Mercaptopurine; Nephritis; Nephrosis; Perinephritis; Prednisolone	1964
THE INHIBITION OF IMMUNOLOGIC RESPONSE BY CHLOROQUINE. Chinese medical journal (Peking, China : 1932), 1964, Volume: 83 Topics: Anaphylaxis; Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Chloroquine; Guinea Pigs; Hemolysin Proteins; Lagomorpha; Mercaptopurine; Mice; Pharmacology; Rabbits; Research	1964
CATARACTS IN CHILDREN ON LONG-TERM CORTICOSTEROID THERAPY. Archives of ophthalmology (Chicago, Ill. : 1960), 1965, Volume: 73 Topics: Adolescent; Adrenal Cortex Hormones; Cataract; Child; Chloroquine; Cyclophosphamide; Drug Therapy; Fluprednisolone; Humans; Lupus Erythematosus, Systemic; Mercaptopurine; Nephrotic Syndrome; Paramethasone; Prednisone; Sulfisoxazole; Toxicology; Triamcinolone	1965
Thiopurine derivatives containing triazole and steroid: synthesis, antimalarial and antileishmanial activities. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2011, Volume: 65, Issue:3 Topics: Acetic Acid; Animals; Antimalarials; Antiprotozoal Agents; Chloroquine; Female; Leishmania; Mercaptopurine; Mice; Plasmodium; Steroids; Triazoles	2011