chloroquine and lidocaine

chloroquine has been researched along with lidocaine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199012 (35.29)18.7374
1990's2 (5.88)18.2507
2000's10 (29.41)29.6817
2010's9 (26.47)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kono, T; Suzuki, K1
Collee, GG; Hanson, GC; Samra, GS1
Capala, J; Carlsson, J1
Bazan, NG; Van Rooijen, LA1
Bazan, NG; Reddy, TS1
Babel, J; Korol, S1
Brdicska, M; Simonyi, I1
Dinnendahl, V; Kalbhen, DA1
Olurin, O1
Balwani, JH; Kulkarni, SD; Phansalkar, AG1
Bennett, JC; Dodson, WH; McBride, WW1
Sándor, R1
Andersson, A; Olsson, S; Tjälve, H1
Kapp, A; Koerner, M; Novacovic, V; Wedi, B1
ASCHHEIM, E; EDDY, DD; FARBER, EM1
Eastman, RT; Huang, R; Khine, P; Su, XZ; Thomas, CJ1
Marceau, F; Parks, A1
Chang, YJ; Chen, YW; Hung, CH; Liu, KS; Wang, JJ1

Reviews

2 review(s) available for chloroquine and lidocaine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[What retinal structures are investigated using ERG and EOG? Morphological and functional correlation].
    Bulletin de la Societe belge d'ophtalmologie, 1974, Volume: 166, Issue:2

    Topics: Acetates; Animals; Chloroquine; Electrooculography; Electroretinography; Glutamates; Glycine; Iodates; Iodine; Iron; Lidocaine; Oxides; Rabbits; Rats; Retina; Retinal Diseases; Sodium; Vitamin A Deficiency

1974

Other Studies

32 other study(ies) available for chloroquine and lidocaine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Internalization and degradation of fat cell-bound insulin. Separation and partial characterization of subcellular vesicles associated with iodoinsulin.
    The Journal of biological chemistry, 1979, Oct-10, Volume: 254, Issue:19

    Topics: Adipose Tissue; Animals; Chloroquine; Dibucaine; Immunoassay; Insulin; Iodine Radioisotopes; Kinetics; Lidocaine; Lysosomes; Male; Procaine; Rats; Receptor, Insulin; Subcellular Fractions; Tetracaine

1979
Chloroquine poisoning: ventricular fibrillation following 'trivial' overdose in a child.
    Intensive care medicine, 1992, Volume: 18, Issue:3

    Topics: Adolescent; Cardiopulmonary Resuscitation; Chloroquine; Drug Overdose; Electrocardiography; Gastric Lavage; Humans; Lidocaine; Male; Ventricular Fibrillation

1992
Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGF: studies on cultured glioma cells.
    International journal of radiation biology, 1991, Volume: 60, Issue:3

    Topics: Cells, Cultured; Chloroquine; Epidermal Growth Factor; Glioma; Humans; Iodine Radioisotopes; Lidocaine

1991
Cationic amphiphilic drugs perturb the metabolism of inosititides and phosphatidic acid in photoreceptor membranes.
    Biochemical and biophysical research communications, 1986, Jan-14, Volume: 134, Issue:1

    Topics: Acetamides; Adenosine Triphosphate; Animals; Brain; Calcium; Cattle; Chloroquine; Dose-Response Relationship, Drug; Lidocaine; Light; Magnesium; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Photoreceptor Cells; Procaine; Propranolol; Rats; Retina; Rod Cell Outer Segment; Tetracaine

1986
Cationic amphiphilic drugs inhibit the synthesis of long-chain fatty acyl coenzyme A in rat brain microsomes.
    FEBS letters, 1985, Mar-11, Volume: 182, Issue:1

    Topics: Acyl Coenzyme A; Anesthetics, Local; Animals; Brain; Chloroquine; Lidocaine; Microsomes; Propranolol; Rats; Tetracaine

1985
[The use of sodium lauryl sulfate volumetric solution in the study of injection solutions].
    Acta pharmaceutica Hungarica, 1973, Volume: 43, Issue:6

    Topics: Atropine; Chloroquine; Chlorpromazine; Codeine; Epinephrine; Injections; Lidocaine; Sodium Dodecyl Sulfate; Solutions; Tripelennamine

1973
[Pharmacology studies on the influencing of chondroitin sulfate decomposition in vitro].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:2

    Topics: Aminopyrine; Anti-Inflammatory Agents; Antipyrine; Aspirin; Chemical Phenomena; Chemistry; Chloroquine; Chondroitin; Copper; Densitometry; Flavonoids; Flufenamic Acid; Glucosamine; Hyaluronoglucosaminidase; Iron; Lidocaine; Male; Malonates; Methylamines; Oxyphenbutazone; Prednisolone; Rutin; Sodium Chloride; Sodium Salicylate; Sulfates; Testis; Triazines

1971
Cortical blindness following convulsions and fever in Nigerian children.
    Pediatrics, 1970, Volume: 46, Issue:1

    Topics: Anti-Bacterial Agents; Anticonvulsants; Blindness; Blood Transfusion; Bronchopneumonia; Cerebral Cortex; Cerebrovascular Circulation; Child, Preschool; Chloroquine; Conjunctivitis; Encephalitis; Female; Fever; Humans; Humeral Fractures; Infant; Lidocaine; Malaria; Male; Nigeria; Seizures

1970
Influence of some antiarrhythmic agents on electrically induced convulsive seizures in rats.
    Indian journal of physiology and pharmacology, 1970, Jul-03, Volume: 14, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Chloroquine; Electroshock; Female; Lidocaine; Male; Phenytoin; Procainamide; Procaine; Quinidine; Quinine; Rats; Seizures; Time Factors; Water

1970
Management of rheumatoid arthritis.
    Southern medical journal, 1969, Volume: 62, Issue:3

    Topics: Adrenal Cortex Hormones; Amitriptyline; Anxiety; Arthritis, Rheumatoid; Aspirin; Attitude of Health Personnel; Barbiturates; Chlordiazepoxide; Chloroquine; Exercise Therapy; Gold; Hospitalization; Hot Temperature; Humans; Indomethacin; Injections, Intra-Articular; Lidocaine; Mechlorethamine; Phenylbutazone; Physical Therapy Modalities; Physician-Patient Relations; Prednisolone; Rest

1969
Treatment of genicular arthrosis with intraarticular Delagil injections.
    Therapia Hungarica (English edition), 1965, Volume: 13, Issue:3

    Topics: Adult; Aged; Chloroquine; Drug Synergism; Humans; Joint Diseases; Knee Joint; Lidocaine; Middle Aged

1965
The uptake of 14C-chloroquine by mouse pancreatic islets in vitro.
    Acta pharmacologica et toxicologica, 1980, Volume: 47, Issue:1

    Topics: Absorption; Animals; Chloroquine; Chlorpromazine; Desipramine; Glucose; Hydrogen-Ion Concentration; Imipramine; Islets of Langerhans; Lidocaine; Mice; Nicotine; Nitrogen; Ouabain; Quinacrine; Temperature

1980
Chronic urticaria serum induces histamine release, leukotriene production, and basophil CD63 surface expression--inhibitory effects ofanti-inflammatory drugs.
    The Journal of allergy and clinical immunology, 2000, Volume: 105, Issue:3

    Topics: Anti-Inflammatory Agents; Antigens, CD; Antigens, Surface; Basophils; Chloroquine; Chronic Disease; Dose-Response Relationship, Drug; Histamine Release; Humans; Leukotrienes; Lidocaine; Platelet Membrane Glycoproteins; Tetraspanin 30; Urticaria

2000
EXPERIMENTAL ANALYSIS OF ISOMORPHIC (KOEBNER) RESPONSE IN PSORIASIS.
    Archives of dermatology, 1964, Volume: 89

    Topics: Chloroquine; Colchicine; Cold Temperature; Dermabrasion; Histology; Humans; Idoxuridine; Iontophoresis; Lidocaine; Psoriasis; Vasodilator Agents; Wounds and Injuries

1964
PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers.
    Scientific reports, 2016, 05-05, Volume: 6

    Topics: Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Drug Resistance; Drug Therapy, Combination; Gene Expression Regulation; Genotype; Lidocaine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Sodium Channel Blockers

2016
Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation.
    Toxicology and applied pharmacology, 2016, 08-15, Volume: 305

    Topics: Amiodarone; Anticholesteremic Agents; Autophagy; beta-Cyclodextrins; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chloroquine; Cholesterol; Cytostatic Agents; Cytotoxins; Human Umbilical Vein Endothelial Cells; Humans; Hydroxychloroquine; Lidocaine; Lovastatin; Lysosomes; Microtubule-Associated Proteins; Poly (ADP-Ribose) Polymerase-1; Procainamide; Quinacrine

2016
Antimalarial primaquine for skin infiltration analgesia in rats.
    The Journal of pharmacy and pharmacology, 2021, Mar-04, Volume: 73, Issue:2

    Topics: Administration, Cutaneous; Analgesia; Anesthetics, Local; Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Lidocaine; Male; Primaquine; Rats; Rats, Sprague-Dawley; Skin; Time Factors

2021