chloroquine and leflunomide

chloroquine has been researched along with leflunomide in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (38.89)29.6817
2010's10 (55.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Kellner, H; Schiemann, U1
Gross, WL; Schnabel, A1
Pirildar, T1
Andel, I; Leeb, BF; Rintelen, B; Sautner, J1
Tłustochowicz, W1
Gergely, P; Poór, G1
Afif, N; Chatelus, E; Goetz, J; Lipsker, D; Sibilia, J; Sordet, C; Sparsa, L1
Castro, C; de la Hoz-Valle, J; Palomino, A; Sánchez, G; Santos-Moreno, PI; Villarreal, L1
Machado-Alba, JE; Machado-Duque, ME; Ruiz, AF1
Bananis, E; Chen, C; Curtis, JR; Fan, H; Hirose, T; Lindsey, S; Mendelsohn, AM; Nduaka, CI; Tanaka, Y; Valdez, H; Wang, L; Winthrop, KL; Yamaoka, K1
Bazzichi, L; Bianchino, L; Caporali, R; Nacci, F; Sinigaglia, L1
Amiri, N; Baldwin, C; De Vera, MA; Rebić, N; Sayre, EC; Zusman, EZ1

Reviews

4 review(s) available for chloroquine and leflunomide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Gastrointestinal side effects in the therapy of rheumatologic diseases].
    Zeitschrift fur Gastroenterologie, 2002, Volume: 40, Issue:11

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Etanercept; Gastrointestinal Diseases; Glucocorticoids; Humans; Hydroxychloroquine; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Rheumatic Diseases; Stomach Ulcer; Sulfasalazine; Tumor Necrosis Factor-alpha

2002
[Rational therapeutic approach in rheumatoid arthritis].
    Annales Academiae Medicae Stetinensis, 2006, Volume: 52 Suppl 2

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Isoxazoles; Joint Prosthesis; Leflunomide; Methotrexate; Prostheses and Implants; Sulfasalazine

2006
[New ways in the management of rheumatoid arthritis in Hungary].
    Lege artis medicinae : uj magyar orvosi hirmondo, 2007, Volume: 17, Issue:10

    Topics: Abatacept; Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Rheumatoid; Autoimmunity; Azathioprine; Chloroquine; Cyclophosphamide; Cyclosporine; Diagnosis, Differential; Early Diagnosis; Etanercept; Humans; Hungary; Immunoconjugates; Immunoglobulin G; Immunologic Factors; Immunosuppressive Agents; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Prognosis; Receptors, Tumor Necrosis Factor; Rituximab; Sulfasalazine; Tumor Necrosis Factor-alpha

2007

Trials

2 trial(s) available for chloroquine and leflunomide

ArticleYear
Leflunomide/chloroquin combination therapy in rheumatoid arthritis: a pilot study.
    Clinical rheumatology, 2006, Volume: 25, Issue:4

    Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Middle Aged; Pilot Projects; Severity of Illness Index

2006
Subcutaneous tocilizumab alone or with a csDMARD in rheumatoid arthritis patients: subanalysis of Italian data from a multicenter phase IIIb/IV trial.
    Clinical rheumatology, 2019, Volume: 38, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Injections, Subcutaneous; Leflunomide; Male; Methotrexate; Middle Aged; Sulfasalazine; Treatment Outcome

2019

Other Studies

12 other study(ies) available for chloroquine and leflunomide

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Evidence-based treatment of methotrexate-resistant rheumatoid arthritis. Combinations of conventional disease-modifying antirheumatic agents].
    Deutsche medizinische Wochenschrift (1946), 2003, Jan-24, Volume: 128, Issue:4

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cyclosporine; Drug Resistance; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydroxychloroquine; Immunosuppressive Agents; Isoxazoles; Leflunomide; Methotrexate; Placebos; Prednisolone; Randomized Controlled Trials as Topic; Sulfasalazine; Time Factors

2003
Treatment of adult-onset Still's disease with leflunomide and chloroquine combination in two patients.
    Clinical rheumatology, 2003, Volume: 22, Issue:2

    Topics: Adult; Antirheumatic Agents; Chloroquine; Drug Therapy, Combination; Humans; Isoxazoles; Leflunomide; Pericardial Effusion; Still's Disease, Adult-Onset

2003
Jessner-Kanof disease induced by leflunomide: a dermal variant of cutaneous lupus?
    Rheumatology international, 2011, Volume: 31, Issue:2

    Topics: Antibodies, Antinuclear; Antirheumatic Agents; Chloroquine; Female; Gold; Humans; Interleukin 1 Receptor Antagonist Protein; Isoxazoles; Leflunomide; Lupus Erythematosus, Cutaneous; Methotrexate; Middle Aged; Treatment Outcome

2011
Treatment of rheumatoid arthritis with methotrexate alone and in combination with other conventional DMARDs using the T2T strategy. A cohort study.
    Clinical rheumatology, 2015, Volume: 34, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cohort Studies; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Prednisolone; Retrospective Studies; Sulfasalazine; Treatment Outcome; Young Adult

2015
Effectiveness of treatment with biologic- and disease-modifying antirheumatic drugs in rheumatoid arthritis patients in Colombia.
    International journal of clinical practice, 2016, Volume: 70, Issue:6

    Topics: Abatacept; Adolescent; Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Child; Child, Preschool; Chloroquine; Cohort Studies; Colombia; Etanercept; Female; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Retrospective Studies; Severity of Illness Index; Young Adult

2016
Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy.
    Arthritis & rheumatology (Hoboken, N.J.), 2017, Volume: 69, Issue:10

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Clinical Trials as Topic; Databases, Factual; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucocorticoids; Herpes Zoster; Humans; Incidence; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Multivariate Analysis; Piperidines; Proportional Hazards Models; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Risk Factors

2017
Perinatal use and discontinuation of disease-modifying anti-rheumatic drugs and biologics in women with rheumatoid arthritis: a cohort study.
    Rheumatology (Oxford, England), 2020, 07-01, Volume: 59, Issue:7

    Topics: Abatacept; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Biological Products; British Columbia; Chloroquine; Cohort Studies; Cyclophosphamide; Cyclosporine; Deprescriptions; Female; Glucocorticoids; Gold Compounds; Humans; Hydroxychloroquine; Interleukin 1 Receptor Antagonist Protein; Leflunomide; Logistic Models; Maternal Age; Methotrexate; Mycophenolic Acid; Odds Ratio; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, First; Rheumatology; Rituximab; Sulfasalazine; Tumor Necrosis Factor Inhibitors

2020