chloroquine has been researched along with lactacystin in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 15 (62.50) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mori, S; Omura, S; Saito, Y; Tanaka, K | 1 |
| Breitschopf, K; Ciechanover, A; Gautschi, I; Ishikawa, T; Rotin, D; Schild, L; Staub, O | 1 |
| Alderson, MR; Briden, AL; Grabstein, KH; Lewinsohn, DM; Reed, SG; Riddell, SR | 1 |
| Beyer, EC; Green, K; Laing, JG; Saffitz, JE; Tadros, PN | 1 |
| Amara, SG; Daniels, GM | 1 |
| Fayadat, L; Franc, JL; Lanet, J; Siffroi-Fernandez, S | 1 |
| Ostrand-Rosenberg, S; Qi, L | 1 |
| Dautry-Varsat, A; Lamaze, C; Rocca, A; Subtil, A | 1 |
| Fujii, Y; Fujimoto, K; Fujita, J; Fujita, T; Masunaga, Y; Mayumi, T; Mori, K; Nakagawa, S; Nakanishi, T; Okada, N; Saito, T; Tanaka, K; Yamamoto, A | 1 |
| Fouchier, RA; Nieuwkoop, NJ; Osterhaus, AD; Rimmelzwaan, GF; Voeten, JT | 1 |
| Gafni, M; Keren, O; Sarne, Y; Shapira, M | 1 |
| Engström, A; Larsson, M; Rask, L; Sakwe, AM | 1 |
| Bradbury, NA; Devor, DC; Hamilton, KL; Jones, HM; Papworth, GD; Syme, CA; Watkins, SC | 1 |
| Couillaud-Battaglia, S; Fortun, Y; Heymann, D; Padrines, M; Redini, F; Tat, SK; Theoleyre, S | 1 |
| Deng, L; Frank, SJ; Fuchs, SY; He, K; Jiang, J; Thangavel, C; Wang, X; Yang, N | 1 |
| Gerelchuluun, T; Han, K; Im, SA; Kim, K; Lee, CK; Lee, YH; Lee, YR; Park, JS; Song, S | 1 |
| Donachie, AM; Mowat, AM; Robson, NC | 1 |
| Lim, G; Mao, J; Sung, B; Wang, S; Yang, L | 1 |
| Qiao, L; Zhang, J | 1 |
| Hou, JC; Pessin, JE; Vicogne, J; Williams, D | 1 |
| Kubo, M; Obata, F; Ohta, E | 1 |
| Han, HJ; Kim, MO; Suh, HN | 1 |
| Ann, EJ; Kim, MY; Kim, SM; Mo, JS; Park, HS; Yoon, JH | 1 |
| Brilot, F; Fonteneau, JF; Gannagé, M; Münz, C | 1 |
24 other study(ies) available for chloroquine and lactacystin
| Article | Year |
|---|---|
Degradation process of ligand-stimulated platelet-derived growth factor beta-receptor involves ubiquitin-proteasome proteolytic pathway.
Topics: Acetylcysteine; Animals; Chloroquine; Cysteine Endopeptidases; Dipeptides; Humans; Multienzyme Complexes; Proteasome Endopeptidase Complex; Rabbits; Receptors, Platelet-Derived Growth Factor; Swine; Ubiquitins | 1995 |
Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; Brefeldin A; Calcium-Binding Proteins; Cell Line; Chloroquine; Cyclopentanes; Cysteine Endopeptidases; Dogs; Endosomal Sorting Complexes Required for Transport; Endosomes; Epithelial Sodium Channels; Epithelium; Half-Life; Ion Channel Gating; Ion Transport; Ligases; Lysosomes; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Nedd4 Ubiquitin Protein Ligases; Nuclear Magnetic Resonance, Biomolecular; Oocytes; Point Mutation; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Conformation; Protein Processing, Post-Translational; Rats; Recombinant Fusion Proteins; Sodium; Sodium Channels; Transfection; Ubiquitin-Protein Ligases; Ubiquitins; Up-Regulation; Xenopus laevis; Xenopus Proteins | 1997 |
Characterization of human CD8+ T cells reactive with Mycobacterium tuberculosis-infected antigen-presenting cells.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; Antigen Presentation; CD8-Positive T-Lymphocytes; Chloroquine; Cysteine Proteinase Inhibitors; Humans; Lymphocyte Cooperation; Mice; Molecular Sequence Data; Mycobacterium tuberculosis; Tuberculosis | 1998 |
Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes.
Topics: Acetylcysteine; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Connexin 43; Cysteine Proteinase Inhibitors; Fluorescent Antibody Technique; Gap Junctions; Hot Temperature; HSP70 Heat-Shock Proteins; Immunoblotting; Leucine; Leupeptins; Lysosomes; Microscopy, Electron; Myocardium; Oligopeptides; Precipitin Tests; Protease Inhibitors; Rats | 1998 |
Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters.
Topics: Acetylcysteine; Animals; Carrier Proteins; Cell Line; Chloroquine; Clathrin; Colforsin; Cycloheximide; Dogs; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocytosis; Enzyme Activation; Humans; Kinetics; Lysosomes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phorbols; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Degradation of human thyroperoxidase in the endoplasmic reticulum involves two different pathways depending on the folding state of the protein.
Topics: Acetylcysteine; Ammonium Chloride; Animals; Antibodies, Monoclonal; Chloroquine; CHO Cells; Cricetinae; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Emetine; Endoplasmic Reticulum; Humans; Multienzyme Complexes; Peroxidase; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Folding; Thyroid Gland | 2000 |
MHC class II presentation of endogenous tumor antigen by cellular vaccines depends on the endocytic pathway but not H2-M.
Topics: Acetylcysteine; Animals; Antigen Presentation; Antigen-Presenting Cells; Antigens, Neoplasm; Antimalarials; Brefeldin A; CD4-Positive T-Lymphocytes; Chloroquine; Coculture Techniques; Cysteine Proteinase Inhibitors; Cytosol; Dose-Response Relationship, Drug; Endocytosis; Endoplasmic Reticulum; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Genes, MHC Class II; Humans; Hybridomas; Leupeptins; Major Histocompatibility Complex; Mice; Muramidase; Plasmids; Primaquine; Protein Synthesis Inhibitors; Protein Transport; Ribonucleases; Transfection; Tumor Cells, Cultured | 2000 |
Involvement of the ubiquitin/proteasome system in sorting of the interleukin 2 receptor beta chain to late endocytic compartments.
Topics: Acetylcysteine; Antimalarials; Cell Line; Chloroquine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endocytosis; Humans; Immunoblotting; Leupeptins; Microscopy, Fluorescence; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Sorting Signals; Protein Subunits; Receptors, Interleukin-2; Recombinant Fusion Proteins; Transfection; Ubiquitins | 2001 |
Effects of lipofectin-antigen complexes on major histocompatibility complex class I-restricted antigen presentation pathway in murine dendritic cells and on dendritic cell maturation.
Topics: Acetylcysteine; Animals; Antigen Presentation; Antigens; Brefeldin A; Cell Line; Cell Survival; Chloroquine; Cytochalasin B; Dendritic Cells; Histocompatibility Antigens Class I; Major Histocompatibility Complex; Mice; Ovalbumin; Phosphatidylethanolamines; Time Factors | 2001 |
Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells.
Topics: Acetylcysteine; Antigen Presentation; B-Lymphocytes; Brefeldin A; Chloroquine; Endosomes; Enzyme Inhibitors; Hematopoietic Stem Cells; Histocompatibility Antigens Class I; Humans; Influenza A virus; Major Histocompatibility Complex; Nucleocapsid Proteins; Nucleoproteins; Peptide Fragments; RNA-Binding Proteins; Viral Core Proteins | 2001 |
Divers pathways mediate delta-opioid receptor down regulation within the same cell.
Topics: Acetylcysteine; Analgesics, Opioid; Animals; Antirheumatic Agents; Chloroquine; Cysteine Proteinase Inhibitors; Diprenorphine; Down-Regulation; Etorphine; Flavonoids; Genistein; GTP-Binding Proteins; Humans; Kidney; MAP Kinase Signaling System; Narcotic Antagonists; Neuroblastoma; Phosphorylation; Radioligand Assay; Receptors, Opioid, delta; Staurosporine; Teprotide; Transfection; Tritium; Tumor Cells, Cultured | 2001 |
Biosynthesis and secretion of parathyroid hormone are sensitive to proteasome inhibitors in dispersed bovine parathyroid cells.
Topics: Acetylcysteine; Animals; Brefeldin A; Calpain; Cattle; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; HSP70 Heat-Shock Proteins; Multienzyme Complexes; Parathyroid Glands; Parathyroid Hormone; Proteasome Endopeptidase Complex; Protein Precursors | 2002 |
Role of the NH2 terminus in the assembly and trafficking of the intermediate conductance Ca2+-activated K+ channel hIK1.
Topics: Acetylcysteine; Amino Acid Motifs; Amino Acid Sequence; Cell Line; Cell Membrane; Chloroquine; Dimerization; DNA, Complementary; Electrophysiology; Endocytosis; Epitopes; Humans; Immunoblotting; Intermediate-Conductance Calcium-Activated Potassium Channels; Leucine; Leucine Zippers; Lysosomes; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Protein Transport; Temperature; Time Factors | 2004 |
OPG/membranous--RANKL complex is internalized via the clathrin pathway before a lysosomal and a proteasomal degradation.
Topics: Acetylcysteine; Animals; Antibodies; Blotting, Western; Cell Line; Cells, Cultured; Chloroquine; Clathrin; Cysteine Proteinase Inhibitors; Enzyme-Linked Immunosorbent Assay; Heparin; Humans; Lysosomes; Mice; Microscopy, Confocal; Osteoclasts; Osteoprotegerin; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; RANK Ligand; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Syndecans | 2006 |
Determinants of growth hormone receptor down-regulation.
Topics: Acetylcysteine; Animals; Cell Line; Chloroquine; Cycloheximide; Down-Regulation; Human Growth Hormone; Humans; Janus Kinase 2; Lysosomes; Mice; Mutation; Phosphorylation; Proteasome Inhibitors; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Rabbits; Receptors, Somatotropin; Recombinant Proteins; Transfection; Tyrosine | 2007 |
Dendritic cells process antigens encapsulated in a biodegradable polymer, poly(D,L-lactide-co-glycolide), via an alternate class I MHC processing pathway.
Topics: Acetylcysteine; Antigen Presentation; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Brefeldin A; Cell Line; Chloroquine; Dendritic Cells; Histocompatibility Antigens Class I; Humans; Lactic Acid; Nanospheres; Ovalbumin; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2007 |
Simultaneous presentation and cross-presentation of immune-stimulating complex-associated cognate antigen by antigen-specific B cells.
Topics: Acetylcysteine; Adoptive Transfer; Animals; Antigen Presentation; Antigens; B-Lymphocytes; Brefeldin A; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Chloroquine; Cysteine Proteinase Inhibitors; Epitopes, B-Lymphocyte; ISCOMs; Kinetics; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Mice, Transgenic; Muramidase; Ovalbumin; Peptide Fragments; Receptors, Antigen, T-Cell; Vaccination | 2008 |
Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation.
Topics: Acetylcysteine; Amino Acid Transport System X-AG; Analgesics, Opioid; Animals; Chloroquine; Excitatory Amino Acid Transporter 3; Humans; Leupeptins; Male; Morphine; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Ubiquitin | 2008 |
Inhibition of lysosomal functions reduces proteasomal activity.
Topics: Acetylcysteine; alpha-Synuclein; Ammonium Chloride; Autophagy; Blotting, Western; Cell Line, Tumor; Chloroquine; Enzyme Inhibitors; HSC70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Hydrogen-Ion Concentration; Lysosomes; Neurons; Proteasome Endopeptidase Complex | 2009 |
The glucose transporter 2 undergoes plasma membrane endocytosis and lysosomal degradation in a secretagogue-dependent manner.
Topics: 3T3-L1 Cells; Acetylcysteine; Animals; Benzoquinones; Cell Membrane; Chloroquine; Endocytosis; Exocytosis; Glucose Transporter Type 1; Glucose Transporter Type 2; Glucose Transporter Type 4; Lactams, Macrocyclic; Lysosomes; Mice | 2009 |
Prevention of intracellular degradation of I2020T mutant LRRK2 restores its protectivity against apoptosis.
Topics: Acetylcysteine; Apoptosis; Chloroquine; Gene Knockdown Techniques; Humans; Hydrogen Peroxide; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Leupeptins; Lysosomes; Parkinson Disease; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Serine-Threonine Kinases | 2010 |
Laminin-111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA-mediated Cx43 phosphorylation and dissociation of Cx43/ZO-1/drebrin complex.
Topics: Acetylcysteine; Actins; Animals; Cell Proliferation; Chloroquine; Connexin 43; Embryonic Stem Cells; Extracellular Matrix; Fibronectins; Focal Adhesion Kinase 1; Gap Junctions; Glycyrrhetinic Acid; Isoquinolines; Laminin; Mice; Multiprotein Complexes; Neuropeptides; Phosphorylation; Protease Inhibitors; Protein Kinase C; Protein Stability; Proteolysis; Receptors, Laminin; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; RNA, Small Interfering; Zonula Occludens-1 Protein | 2012 |
Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase.
Topics: Acetylcysteine; Ammonium Chloride; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Gene Knockout Techniques; HEK293 Cells; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Leupeptins; Lysosomes; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Presenilin-1; Presenilin-2; Proteasome Inhibitors; Proteolysis; Receptor, Notch1; Transcription, Genetic; Transcriptional Activation; Ubiquitination | 2012 |
The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer.
Topics: Acetylcysteine; Antigen Presentation; Antigens, Neoplasm; Autophagy; Autophagy-Related Protein 12; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Chloroquine; Dendritic Cells; Endocytosis; Epitopes, T-Lymphocyte; Histocompatibility Antigens Class II; Humans; Immunotherapy, Adoptive; Leupeptins; Lymphocyte Activation; Lysosomal-Associated Membrane Protein 2; Melanoma; Membrane Proteins; RNA Interference; RNA, Small Interfering; Small Ubiquitin-Related Modifier Proteins | 2016 |