chloroquine has been researched along with hypoxanthine in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (22.22) | 18.7374 |
| 1990's | 8 (29.63) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Ikeda, I; Kamiyama, T; Matsubara, J; Niinuma, S | 1 |
| Berman, PA; Freese, JA; Human, L | 1 |
| Berman, PA; Human, L | 1 |
| Kocan, AA; Mitema, ES; Mukolwe, SW; Sangiah, S; Sherban, D | 1 |
| Le Bras, J; Malhotra, K; Salmon, D; Vilde, JL | 1 |
| Van Dyke, K; Wimmer, M; Ye, ZG | 1 |
| Brasseur, P; Druilhe, P; Pathe-Diallo, M | 1 |
| Ancelin, ML; Philippot, JR; Thuet, MJ; Vial, HJ | 1 |
| Geary, TG; Jensen, JB; Vande Waa, JA; Yayon, A; Yayon, M | 1 |
| Divo, AA; Geary, TG; Jensen, JB | 1 |
| Brodasky, TF; Gluzman, IY; Krogstad, DJ; Parquette, AR; Phillips, GW; Seaberg, LS | 1 |
| Bancroft, JE; Gibbins, BL; Hinrichs, DJ; Makler, MT; Piper, RC; Ries, JM; Williams, JA | 1 |
| Holloway, P; Krishna, S; Pasvol, G; ter Kuile, F; White, NJ | 1 |
| Gupta, RC; Pandey, VC; Puri, SK; Singh, S; Singh, SK; Srivastava, R | 1 |
| Elford, BC; Ginsburg, H; Krugliak, M; Lew, VL; Tiffert, T | 1 |
| Callapa, J; Mallié, M; Mitaine-Offer, AC; Sauvain, M; Valentin, A; Zèches-Hanrot, M | 1 |
| Go, ML; Wilairat, P; Wu, X | 1 |
| Gordeuk, VR; Lovejoy, DB; Loyevsky, M; Richardson, DR; Walcourt, A | 1 |
| Basco, LK | 1 |
| Ramanitrahasimbola, D; Rasoanaivo, P; Ratsimamanga, S; Vial, H | 1 |
| Barrends, M; Jones, J; Kosaisavee, V; Kyle, DE; Lek-Uthai, U; Nosten, F; Price, R; Russell, B; Suwanarusk, R | 1 |
| Adagu, I; Dar, O; Khan, MS | 1 |
| Co, EM; Dennull, RA; Johnson, JD; Reinbold, DD; Waters, NC | 1 |
| Basco, L; Boyer, J; Ibrahim, H; Nepveu, F; Tahar, R; Thompson, E; Vivas, L | 1 |
| André-Barrès, C; Mallet-Ladeira, S; Maynadier, M; Ruiz, J; Vial, H | 1 |
| Andrews, KT; Arnold, MS; Chua, MJ; Engel, JA; Fisher, GM; Skinner-Adams, TS | 1 |
| Burckhardt, BB; de Carvalho, LP; Held, J; Herrmann, J; Knaab, T; Kreidenweiss, A; Kurz, T; Mavraj-Husejni, A; Müller, R; Niepoth, E | 1 |
27 other study(ies) available for chloroquine and hypoxanthine
| Article | Year |
|---|---|
Incorporation of [3H]hypoxanthine by short-term cultured Theileria sergenti and its inhibition by drugs.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Cattle; Cells, Cultured; Chloroquine; Diminazene; Dose-Response Relationship, Drug; Erythrocytes; Hypoxanthine; Hypoxanthines; Immune Sera; Pyrimethamine; Quinine; Theileria | 1992 |
Xanthine oxidase inhibits growth of Plasmodium falciparum in human erythrocytes in vitro.
Topics: Animals; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Erythrocytes; Glycine; Humans; Hypoxanthine; Hypoxanthines; Plasmodium falciparum; Purines; Superoxide Dismutase; Xanthine Oxidase | 1991 |
Hypoxanthine depletion induced by xanthine oxidase inhibits malaria parasite growth in vitro.
Topics: Adenine; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Catalase; Chloroquine; Erythrocytes; Glycine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Plasmodium falciparum; Purines; Superoxide Dismutase; Xanthine Oxidase | 1991 |
Activity of buparvaquone against Theileria cervi in white-tailed deer.
Topics: Animals; Antiprotozoal Agents; Apicomplexa; Cells, Cultured; Chloroquine; Deer; Erythrocytes; Hypoxanthine; Hypoxanthines; Imidocarb; Naphthoquinones; Theileriasis | 1991 |
Potentiation of chloroquine activity against Plasmodium falciparum by the peroxidase-hydrogen peroxide system.
Topics: Animals; Cells, Cultured; Chloroquine; Drug Synergism; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Mefloquine; Peroxidases; Plasmodium falciparum; Quinine | 1990 |
Effect of artemisinin (qinghaosu) and chloroquine on drug-sensitive and drug-resistant strains of Plasmodium falciparum malaria: use of [2,8-3H]adenosine as an alternative to [G-3H]hypoxanthine in the assessment of in vitro antimalarial activity.
Topics: Adenosine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Malaria; Mice; Plasmodium falciparum; Sesquiterpenes | 1987 |
Low sensitivity to chloroquine and quinine of Plasmodium falciparum isolates from Guinea in March 1986.
Topics: Africa, Western; Animals; Chloroquine; Drug Resistance; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Plasmodium falciparum; Quinine | 1987 |
Differential effects of chloroquine on the phospholipid metabolism of Plasmodium-infected erythrocytes.
Topics: Animals; Chloroquine; Erythrocytes; Fatty Acids; Hypoxanthine; Hypoxanthines; Isoleucine; Macaca fascicularis; Malaria; Phospholipids; Plasmodium | 1988 |
Stage-dependent effects of chloroquine on Plasmodium falciparum in vitro.
Topics: Animals; Chloroquine; DNA; Dose-Response Relationship, Drug; Erythrocytes; Glucose; Hypoxanthine; Hypoxanthines; Kinetics; Plasmodium falciparum; RNA | 1983 |
An in vitro assay system for the identification of potential antimalarial drugs.
Topics: Animals; Antimalarials; Cattle; Chloramphenicol; Chloroquine; Clindamycin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Piperidines; Plasmodium falciparum; Quinazolines; Quinazolinones; Rabbits | 1983 |
Clindamycin activity against chloroquine-resistant Plasmodium falciparum.
Topics: Chloroquine; Clindamycin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Synergism; Hypoxanthine; Hypoxanthines; Plasmodium falciparum | 1984 |
Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity.
Topics: Animals; Azure Stains; Chloroquine; Colorimetry; Dose-Response Relationship, Drug; Drug Resistance; Hypoxanthine; Hypoxanthines; L-Lactate Dehydrogenase; Plasmodium falciparum; Regression Analysis; Reproducibility of Results | 1993 |
Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria.
Topics: Animals; Antimalarials; Artemisinins; Cell Differentiation; Chloroquine; Drugs, Chinese Herbal; Hypoxanthine; Hypoxanthines; Lactates; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes | 1993 |
Characterization of simian malarial parasite (Plasmodium knowlesi)-induced putrescine transport in rhesus monkey erythrocytes. A novel putrescine conjugate arrests in vitro growth of simian malarial parasite (Plasmodium knowlesi) and cures multidrug resis
Topics: Aminoquinolines; Animals; Antimalarials; Biological Transport, Active; Chloroquine; Drug Resistance, Multiple; Erythrocytes; Female; Hypoxanthine; In Vitro Techniques; Kinetics; Macaca mulatta; Malaria; Male; Mice; Plasmodium knowlesi; Plasmodium yoelii; Putrescine; Temperature | 1997 |
Potent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum.
Topics: Animals; Antifungal Agents; Antimalarials; Cells, Cultured; Chloroquine; Clotrimazole; Growth Inhibitors; Histocytochemistry; Hypoxanthine; Mefloquine; Plasmodium falciparum | 2000 |
Antiplasmodial activity of aspidosperma indole alkaloids.
Topics: Alkaloids; Animals; Antimalarials; Aspidosperma; Cell Line; Chloroquine; Drug Resistance; Humans; Hypoxanthine; Indole Alkaloids; Indoles; Inhibitory Concentration 50; Molecular Structure; Plant Extracts; Plasmodium falciparum; Quinolines; Structure-Activity Relationship; Toxicity Tests | 2002 |
Antimalarial activity of ferrocenyl chalcones.
Topics: Animals; Antimalarials; Chalcone; Chloroquine; Drug Resistance; Ferrous Compounds; Hypoxanthine; Inhibitory Concentration 50; Metallocenes; Plasmodium falciparum; Structure-Activity Relationship | 2002 |
Novel aroylhydrazone and thiosemicarbazone iron chelators with anti-malarial activity against chloroquine-resistant and -sensitive parasites.
Topics: Animals; Antimalarials; Antineoplastic Agents; Cell Line, Tumor; Chloroquine; Drug Resistance; Erythrocytes; Humans; Hydrazones; Hypoxanthine; Iron Chelating Agents; Molecular Structure; Plasmodium falciparum; Thiosemicarbazones; Tritium | 2004 |
Molecular epidemiology of malaria in cameroon. XX. Experimental studies on various factors of in vitro drug sensitivity assays using fresh isolates of Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Hematocrit; Humans; Hypoxanthine; Parasitic Sensitivity Tests; Plasmodium falciparum | 2004 |
Malagashanine potentiates chloroquine antimalarial activity in drug resistant Plasmodium malaria by modifying both its efflux and influx.
Topics: Alkaloids; Animals; Antimalarials; Chloroquine; Culture Media; Drug Resistance; Drug Synergism; Erythrocytes; Glucose; Hypoxanthine; Life Cycle Stages; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Time Factors | 2006 |
Plasmodium vivax: isotopic, PicoGreen, and microscopic assays for measuring chloroquine sensitivity in fresh and cryopreserved isolates.
Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Cryopreservation; Female; Fluorescent Dyes; Freezing; Humans; Hypoxanthine; Inhibitory Concentration 50; Malaria, Vivax; Male; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium vivax; Sensitivity and Specificity; Tritium | 2006 |
The potential use of methotrexate in the treatment of falciparum malaria: in vitro assays against sensitive and multidrug-resistant falciparum strains.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Humans; Hypoxanthine; Malaria, Falciparum; Methotrexate; Nucleic Acid Synthesis Inhibitors; Parasitic Sensitivity Tests; Plasmodium falciparum; Tritium | 2008 |
Assessment of malaria in vitro drug combination screening and mixed-strain infections using the malaria Sybr green I-based fluorescence assay.
Topics: Animals; Antimalarials; Artemisinins; Benzothiazoles; Chloroquine; Diamines; Drug Combinations; Drug Evaluation, Preclinical; Drug Interactions; Fluorescent Dyes; Hypoxanthine; Mefloquine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines | 2009 |
Indolone-N-oxide derivatives: in vitro activity against fresh clinical isolates of Plasmodium falciparum, stage specificity and in vitro interactions with established antimalarial drugs.
Topics: Adult; Antimalarials; Artemisinins; Cameroon; Chloroquine; Drug Interactions; Drug Resistance; Female; Humans; Hypoxanthine; Indoles; Malaria, Falciparum; Male; Nitrogen Oxides; Oxidation-Reduction; Parasitic Sensitivity Tests; Plasmodium falciparum | 2011 |
Design, synthesis and evaluation of new tricyclic endoperoxides as potential antiplasmodial agents.
Topics: Aminoquinolines; Antimalarials; Artemisinins; Chloroquine; Drug Design; Erythrocytes; Free Radicals; Humans; Hypoxanthine; Inhibitory Concentration 50; Iron; Oxidation-Reduction; Peroxides; Plasmodium falciparum; Tritium | 2014 |
Adaptation of the [3H]Hypoxanthine Uptake Assay for In Vitro-Cultured Plasmodium knowlesi Malaria Parasites.
Topics: Animals; Antimalarials; Chloroquine; Clindamycin; Hypoxanthine; Inhibitory Concentration 50; Malaria; Plasmodium falciparum; Plasmodium knowlesi; Proguanil; Triazines | 2016 |
Quantification of Plasmodium falciparum HRP-2 as an alternative method to [
Topics: Animals; Antimalarials; Chloroquine; Hypoxanthine; Malaria, Falciparum; Parasites; Plasmodium falciparum | 2023 |