Compounds > chloroquine

chloroquine and hydralazine

chloroquine has been researched along with hydralazine in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (41.18)	18.7374
1990's	1 (5.88)	18.2507
2000's	6 (35.29)	29.6817
2010's	3 (17.65)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Holmes, J; Sapeika, N; Zwarenstein, H	2
Johansson, B	1
Burnham, TK; Fine, G; Lester, RS; Murray, K	1
Balevska, N	1
Graeme, ML; John, M; Sigg, EB	1
Allen, LV; Erickson, MA	1
GOLDBERG, LC	1

Reviews

2 review(s) available for chloroquine and hydralazine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Side effects of drugs. 4. Drug induced polyneuropathies and myopathies]. Lakartidningen, 1969, Dec-15, Volume: 66 Topics: Adrenocorticotropic Hormone; Chloroquine; Glucocorticoids; Humans; Hydralazine; Isoniazid; Muscular Diseases; Neurons, Afferent; Nitrofurans; Peripheral Nervous System Diseases; Thalidomide; Vincristine	1969

Other Studies

15 other study(ies) available for chloroquine and hydralazine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Effect of quinoline, phthalazine and coumarin derivatives on the absorbance of NADPH. Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1 Topics: Chloroquine; Coumarins; Heterocyclic Compounds; Hydralazine; Indophenol; NADP; Novobiocin; Quinacrine; Quinidine; Quinine; Quinolines; Spectrophotometry; Warfarin	1974
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro. Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2 Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts	1973
Immunologic concepts of light reactions in lupus erythematosus and polymorphous light eruptions. I. The mechanism of action of hydroxychloroquine. Archives of dermatology, 1967, Volume: 96, Issue:1 Topics: Antibodies, Antinuclear; Autoantibodies; Chloroquine; DNA; Erythema; Humans; Hydralazine; Hydroxychloroquine; Injections, Intradermal; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Methotrexate; Methylprednisolone; Prednisone; Protein Binding; Skin Manifestations; Ultraviolet Rays	1967
[On clinical features, etiology and treatment of acute lupus erythematosus]. Dermatologische Wochenschrift, 1965, Jul-24, Volume: 151, Issue:30 Topics: Adolescent; Adult; Aged; Animals; Anti-Bacterial Agents; Blood Transfusion; Child; Chloroquine; Female; Guinea Pigs; Humans; Hydralazine; Lupus Erythematosus, Discoid; Male; Middle Aged; Quinine; Vitamins	1965
Induction of periarthritis by oral administration of 6-sulfanilamidoindazole and its treatment in rats. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1 Topics: Animals; Aspirin; Chloroquine; Cloxacillin; Hydralazine; Hydrocortisone; Indomethacin; Male; Mercaptopurine; Methotrexate; Morphine; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Periarthritis; Phenylbutazone; Rats; Sulfinpyrazone; Sulfonamides	1967
Stability of alprazolam, chloroquine phosphate, cisapride, enalapril maleate, and hydralazine hydrochloride in extemporaneously compounded oral liquids. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Sep-15, Volume: 55, Issue:18 Topics: Alprazolam; Chloroquine; Chromatography, High Pressure Liquid; Cisapride; Drug Compounding; Drug Stability; Enalapril; Hydralazine; Pharmaceutical Solutions	1998
A THIRTY YEAR EVALUATION OF LUPUS ERYTHEMATOSUS. Medical times, 1964, Volume: 92 Topics: Adrenal Cortex Hormones; Anticonvulsants; Antitubercular Agents; Appetite Depressants; Chloroquine; Hydralazine; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Pregnancy; Toxicology	1964