chloroquine has been researched along with histamine in 84 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (25.00) | 18.7374 |
1990's | 6 (7.14) | 18.2507 |
2000's | 7 (8.33) | 29.6817 |
2010's | 37 (44.05) | 24.3611 |
2020's | 13 (15.48) | 2.80 |
Authors | Studies |
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Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Biagini, GA; Chandramohanadas, R; Darling, C; DeGrado, WF; Diamond, SL; Fisher, N; Greenbaum, DC; Jing, H; Jo, H; Lucumi, E; Napper, AD; Shone, AE; Ward, SA | 1 |
Bajdekoff, B; Bojkov, B; Durmischev, A | 1 |
Scott, WA; Solomon, B | 1 |
Lot, TY | 2 |
Amankwaah, DK; Sackeyfio, AC; Yahaya, AS | 1 |
Yamamoto, K | 1 |
Dietrich, FM; Komarek, A; Pericin, C | 1 |
Ayitey-Smith, E; Boye, GL | 1 |
Horváth-Kovács, A; Romhányi, G | 1 |
Falke, D; Kahl, GF | 1 |
Aviado, DM; Reutter, HA | 1 |
Fujimura, H; Ito, M; Suzuki, Y; Yamagami, I | 1 |
Aviado, DM; Cambar, P; Sadavongvivad, C | 1 |
Klebanov, BM; Trinus, FP | 1 |
Gieldanowski, J; Pelczarska, A | 1 |
Aviado, DM; Belej, M; Ruiz, R | 1 |
Wiskemann, A | 1 |
Epstein, JH; Sams, WM; Winkelmann, RK | 1 |
Dale, MM; Ladd, R | 1 |
Fortes, ZB; Garcia Leme, J; Scivoletto, R | 1 |
Griswold, DE; Walz, DT | 1 |
Abila, B; Ambakederemo, AW; Asomugha, L; Ezeamuzie, IC; Igbigbi, PS | 1 |
Donatelli, P; Giuliani, L; Gustafsson, LL; Marchi, G; Pacifici, GM | 1 |
Abiose, AK; Blaschke, TF; Grossmann, M; Hoffman, BB; Tangphao, O | 1 |
Horio, S; Ishida, Y; Moritoki, H; Nagare, T | 1 |
Afolabi, BM; Bashirelah, N; Enwonwu, CO; Idigbe, EO; Salako, LO | 1 |
Jain, M; Jain, R; Kaur, N; Singh, PP; Singh, S; Vangapandu, S | 1 |
ORINSTEIN, E | 1 |
DASHPUTRA, PG; DESHPANDE, VR; SHARMA, ML | 1 |
Green, AD; Lehto, SG; Mogil, JS; Smith, SB; Young, KK | 1 |
Akiyama, K; Kajiwara, K; Morishima, H; Yanagihara, Y | 1 |
Anderson, DJ; Chen, ZF; Dong, X; Geng, Y; Guan, Y; Kim, A; Kim, S; Kollarik, M; Liu, Q; Patel, KN; Ru, F; Surdenikova, L; Tang, Z; Undem, BJ; Weng, HJ | 1 |
Su, X; Wu, G | 1 |
Han, SK; Kim, D; Kim, SJ; Lee, CJ; Lee, J; Lee, SJ; Min, H; Park, GH; Simon, MI; Wall, E | 1 |
Bautista, DM; Bifolck-Fisher, A; Dong, X; Gerhold, KA; Liu, Q; Patel, KN; Wilson, SR | 1 |
Chai, J; Han, N; Zu, JY | 1 |
McCoy, ES; Taylor-Blake, B; Zylka, MJ | 1 |
Akiyama, T; Carstens, EE; Carstens, MI; Tominaga, M | 1 |
Huang, P; Mac, EA; Malkmus, S; Marino, M; Robertshaw, E; Shatterman, Y; Yaksh, TL | 1 |
Akiyama, T; Blansit, K; Carstens, E; Carstens, MI; Davoodi, A; Horwitz, A; Nagamine, M; Tominaga, M | 2 |
Cui, Y; Dong, X; Guan, Y; Han, L; He, S; Kim, Y; Lamotte, RH; Li, Z; Liu, Q; Ma, C; McNeil, B; Nie, H; Patel, KN; Qu, L; Tang, Z; Weng, HJ; Xiao, B | 1 |
Giesler, GJ; Moser, HR | 1 |
Brenner, DS; Gereau, RW; Gutmann, DH; O'Brien, DE | 1 |
Hoon, MA; Mishra, SK | 1 |
Chen, JY; Ding, YQ; Huang, Y; Jiang, GY; Song, NJ; Wang, QX; Zhang, L | 1 |
Choi, JH; Dahlén, B; Dahlén, SE; Ekoff, M; James, A; Nilsson, G | 1 |
Akiyama, T; Carstens, E; Carstens, MI; Piecha, D; Steppan, S | 1 |
Copits, BA; Davidson, S; Gereau, RW; Ghetti, A; Page, G; Zhang, J | 1 |
Akiyama, T; Carstens, E; Carstens, MI; Takamori, K; Tominaga, M | 1 |
Chung, SJ; Jang, YH; Lee, CJ; Lee, H; Lee, SJ; Lim, H; Min, H | 1 |
Giesler, GJ; Jansen, NA | 1 |
Davidson, S; Gereau, RW; Leitges, M; Valtcheva, MV; Zhao, C | 1 |
Pradhananga, S; Shim, WS | 1 |
Akiyama, T; Carstens, E; Carstens, MI; Curtis, E; Nguyen, T | 1 |
An, SS; Camoretti-Mercado, B; Deshpande, DA; Liggett, SB; Pauer, SH; Smith, DC; Yong, HM | 1 |
Kawasaki, H; Kusube, F; Naito, H; Ogawa, H; Takamori, K; Tominaga, M; Tomooka, Y; Yamakura, F | 1 |
Dong, X; Herbstsomer, RA; Jurcakova, D; Meixong, J; Ru, F; Sun, H; Undem, BJ | 1 |
Borad, N; Catich, E; Li, N; McKemy, DD; Ongun, S; Palkar, R; Sarkisian, A | 1 |
Han, MK; Im, SY; Im, YN; Kim, HK; Lee, HK; Lee, YD; Park, JS; Song, HR | 1 |
Giesler, GJ; Khasabov, SG; Lipshetz, B; Netoff, TI; Simone, DA; Truong, H | 1 |
Akiyama, T; Carstens, E; Davoodi, A; Follansbee, T; Fujii, M; Iodi Carstens, M; Nagamine, M | 1 |
Bai, Y; Feng, YP; Li, H; Wang, XD; Yang, G | 1 |
Akiyama, T; Hashimoto, T; Henry, TD; Sakai, K; Sanders, KM | 1 |
Bai, Y; Chen, YB; Huang, J; Li, JN; Li, YQ; Sun, Y; Yang, J | 1 |
Chen, M; Guo, SS; Hu, J; Huang, C; Li, Y; Liu, MG; Luo, HQ; Su, XY; Sun, W; Xu, TL; Yuan, Y; Zhu, MX | 1 |
Akiyama, T; Hashimoto, T; Sakai, K; Yosipovitch, G | 1 |
Bäumer, W; Fukuyama, T; Ganchingco, JRC; Yoder, JA | 1 |
Ebihara, K; Funahashi, H; Haruta-Tsukamoto, A; Ishida, Y; Matsuo, T; Miyahara, Y; Naono-Nakayama, R; Nishimori, T | 1 |
Huang, Z; Liu, C; Liu, XG; Mai, CL; Mai, JZ; Zhang, H; Zhang, J; Zhou, X | 1 |
Alvaro, CG; Basbaum, AI; Bernstein, M; Braz, JM; Craik, V; Hamel, KA; Yamanaka, H | 1 |
Budke, D; Diaz, P; Gadotti, VM; Kreitinger, JM; Wageling, NB; Zamponi, GW | 1 |
Akiyama, T; Funahashi, H; Hashimoto, T; Lozada, T; Pavlenko, D; Sakai, K; Yosipovitch, G | 1 |
Funahashi, H; Haruta-Tsukamoto, A; Ishida, Y; Miyahara, Y; Nishimori, T | 1 |
Gadotti, VM; Zamponi, GW | 1 |
Luo, Y; Malewicz, N; Nie, H; Pan, J; Rong, J; Situ, Y; Tang, D; Verkhratsky, A; Wang, Y; Ye, K; Zhang, Z; Zhao, J; Zhu, T | 1 |
Heo, Y; Jeon, H; Lee, Y; Namkung, W; Ryu, K | 1 |
Li, BM; Liu, Y; Liu, YU; Ma, CL; Mou, B; Pan, H; Peng, J; Xiong, MT; Yang, Y; Yun, X; Zhang, JY; Zhang, QR; Zhao, HX | 1 |
Funahashi, H; Haruta-Tsukamoto, A; Hirano, Y; Ishida, Y; Kanemaru-Kawazoe, A; Kogoh, Y; Miyahara, Y; Nishimori, T | 1 |
Akiyama, T; Bystrom, L; Ishida, H; Markan, A; Pavlenko, D; Todurga Seven, Z; Verpile, R | 1 |
Bo, BS; Chen, WZ; Ding, WQ; Liang, ZF; Shen, TY; Shi, XX; Sun, YG; Wang, LH; Wang, M; Wang, XF; Yuan, L | 1 |
2 review(s) available for chloroquine and histamine
Article | Year |
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[Therapeutic aspects of Behcet's syndrome].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Behcet Syndrome; Chloroquine; gamma-Globulins; Glucocorticoids; Gold; Gonadal Steroid Hormones; Histamine; Humans; Immunosuppressive Agents; Middle Aged | 1971 |
[Biochemical mechanisms of the action of non-steroid anti-inflammatory agents (literature review)].
Topics: Adenosine Triphosphate; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Carboxy-Lyases; Chloroquine; Chymotrypsin; Glucose-6-Phosphate Isomerase; Histamine; Histidine; Indomethacin; Kallidin; Kinins; Lactates; Mefenamic Acid; Oxidative Phosphorylation; Peptide Hydrolases; Phenacetin; Phenylbutazone; Quinolines; Rats; Sodium Salicylate | 1972 |
1 trial(s) available for chloroquine and histamine
Article | Year |
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Effects of two antihistamines on chloroquine and histamine induced weal and flare in healthy African volunteers.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Black People; Chloroquine; Clemastine; Cross-Over Studies; Histamine; Humans; Injections, Intradermal; Male; Pruritus; Pyrilamine; Single-Blind Method | 1994 |
81 other study(ies) available for chloroquine and histamine
Article | Year |
---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.
Topics: Animals; Antimalarials; Drug Resistance, Multiple; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum | 2010 |
[The effect of chloroquine diphosphate upon tissue mast cells in rat's skin (author's transl)].
Topics: Animals; Cell Count; Chloroquine; Histamine; Histidine Decarboxylase; Mast Cells; Rats; Skin | 1977 |
Adenosine 3',5'-cyclic monophosphate and morphology in Neurospora crassa: drug-induced alterations.
Topics: Adenylyl Cyclases; Antimalarials; Atropine; Chloroquine; Cyclic AMP; Histamine; Kinetics; Neurospora; Neurospora crassa; Phosphoric Diester Hydrolases; Quinidine; Quinine; Theophylline | 1975 |
Smooth muscle sensitization and neuromuscular depression induced by chronic administration of antimalarial drugs.
Topics: Acetylcholine; Animals; Chickens; Chloroquine; Culture Techniques; Dose-Response Relationship, Drug; Histamine; Male; Muscle Contraction; Muscle, Smooth; Muscles; Neuromuscular Junction; Norepinephrine; Potassium Chloride; Quinacrine | 1992 |
Interaction between chloroquine and indomethacin in airways smooth muscle in vivo.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bronchi; Chloroquine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Phospholipases A; Phospholipases A2; Trachea | 1987 |
Hypersensitivity in mice. II. The effect of chemical compounds on systemic active anaphylaxis and on anaphylaxis-like reactions in normal and B. pertussis-pretreated mice.
Topics: Anaphylaxis; Animals; Antigens; Aspirin; Bordetella pertussis; Chloroquine; Corticosterone; Cortisone; Dexamethasone; Diphenhydramine; Flumethasone; gamma-Globulins; Histamine; Hydrocortisone; Hypersensitivity; Immunization, Secondary; Immunosuppressive Agents; Male; Methysergide; Mice; Muramidase; Ouabain; Paramethasone; Pertussis Vaccine; Prednisolone; Prednisone; Serotonin; Serum Albumin, Bovine; Tranquilizing Agents; Tripelennamine | 1971 |
Effect of chloroquine on histamine-induced bronchial asthma in the guinea-pig.
Topics: Animals; Asthma; Chloroquine; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Lung; Male | 1974 |
Ultrastructural changes of collagen fibres in wheals produced by intracutaneous injection of different substances in the rat.
Topics: Acids; Acridines; Animals; Chloroquine; Collagen; Edetic Acid; Histamine; Injections, Intradermal; Microscopy, Polarization; Phosphates; Rats; Skin; Sodium Chloride; Staining and Labeling | 1967 |
[Inhibition of giant cell formation by compound 48-80 after infection with Herpesvirus hominis. II. The activation of lysosomes].
Topics: Animals; Butylamines; Chloroquine; Culture Media; Culture Techniques; Cytopathogenic Effect, Viral; Cytoplasm; Fluorometry; Histamine; Histamine Release; Hydrogen-Ion Concentration; Kidney; Lysosomes; Microscopy, Electron; Microscopy, Fluorescence; Microscopy, Phase-Contrast; p-Methoxy-N-methylphenethylamine; Peritoneum; Phosphates; Rabbits; Rats; Simplexvirus; Staining and Labeling | 1970 |
Pathologic physiology and chemotherapy of Plasmodium berghei. IX. Gastric secretion and the influence of 1-aminocyclopentane carboxylic acid (WR 14, 997 or cycloleucine).
Topics: Amino Acids; Animals; Anorexia Nervosa; Antimalarials; Chloroquine; Chlorphentermine; Cyclopentanes; Electron Transport Complex IV; Gastric Acidity Determination; Gastric Juice; Heart; Heart Atria; Histamine; Humans; Malaria; Methods; Mice; Myocardium; Plasmodium; Succinate Dehydrogenase; Time Factors | 1969 |
[Influence of various drugs on tissue permeability. (4)].
Topics: Aminocaproates; Aminopyrine; Animals; Anti-Inflammatory Agents; Barbiturates; Chloroquine; Chymotrypsin; Coloring Agents; Connective Tissue; Cyclizine; Cyclohexanecarboxylic Acids; Cyproheptadine; Dexamethasone; Diphenhydramine; Flufenamic Acid; Glucocorticoids; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hyaluronoglucosaminidase; Indomethacin; Male; Peptide Hydrolases; Permeability; Phenylbutazone; Piperazines; Prednisolone; Protease Inhibitors; Rats; Salicylates | 1970 |
Cardiopulmonary effects of antimalarial drugs. 1. 4-Aminoquinolines: chloroquine quinetholate.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Asthma; Blood Pressure; Chloroform; Chloroquine; Dopamine; Electrocardiography; Female; Heart Rate; Histamine; Histamine H1 Antagonists; Lung; Male; Mice; Norepinephrine; Ovalbumin; Quinolines; Rabbits; Serotonin; Vascular Resistance | 1970 |
Mediators and nonsteroid antiinflammatory drugs in immunologically specific and nonspecific inflammatory processes.
Topics: Adjuvants, Immunologic; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Bradykinin; Chloroquine; Dermatitis, Contact; Drug Antagonism; Guinea Pigs; Histamine; Hypersensitivity, Delayed; Immune System Diseases; Indomethacin; Inflammation; Mice; Phenylbutazone; Rabbits; Rats; Salicylates; Serotonin; Skin Transplantation; Transplantation Immunology; Transplantation, Homologous; Xylenes | 1971 |
Cardiopulmonary effects of antimalarial drugs. II. Phenanthrenemethanols.
Topics: Anesthesia; Animals; Antimalarials; Aorta; Blood Pressure; Brain Chemistry; Bronchi; Cardiac Output; Chloroform; Chloroquine; Dopamine; Electrocardiography; Heart; Histamine; Lung; Lung Compliance; Male; Methanol; Mice; Myocardium; Norepinephrine; Phenanthrenes; Rabbits; Serotonin; Vascular Resistance | 1970 |
[Pharmacologic light protection].
Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Chloroquine; Coloring Agents; Cysteamine; Histamine; Histidine; Humans; Mice; Phenylbutazone; Photosensitivity Disorders; Phytotherapy; Plants, Medicinal; Prednisone; Radiation-Protective Agents; Rutin; Serotonin; Tryptophan; Ultraviolet Rays | 1968 |
Solar urticaria. Investigation of pathogenetic mechanisms.
Topics: Adult; Blood Circulation; Capillary Permeability; Chloroquine; Epinephrine; Histamine; Humans; Kinins; Male; Radiation Effects; Serum Albumin; Skin; Skin Tests; Sunlight; Temperature; Ultraviolet Rays; Urticaria | 1969 |
A comparison of dimaprit, nordimaprit, methylamine and chloroquine as inhibitors of mitogen-induced lymphocyte activation.
Topics: Cells, Cultured; Chloroquine; Chromium Radioisotopes; Concanavalin A; Dimaprit; Histamine; Humans; Lymphocyte Activation; Lymphocytes; Methylamines; Mitogens; Phytohemagglutinins; Thiourea; Thymidine | 1984 |
Vascular reactivity in diabetes mellitus: possible role of insulin on the endothelial cell.
Topics: Adrenalectomy; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bradykinin; Capillary Permeability; Chloroquine; Diabetes Mellitus, Experimental; Endothelium; Histamine; Indomethacin; Insulin; Male; Rats; Rats, Inbred Strains; Splanchnic Circulation | 1984 |
Effect of selected immunoregulatory agents on low-grade contact sensitivity.
Topics: Adjuvants, Immunologic; Animals; Chloroquine; Dermatitis, Contact; Dose-Response Relationship, Drug; Histamine; Male; Mice; Mice, Inbred C57BL; Oxazolone; Penicillamine; Thymosin | 1982 |
Stereoselective inhibition by chloroquine of histamine N-methyltransferase in the human liver and brain.
Topics: Adult; Aged; Brain; Chloroquine; Dose-Response Relationship, Drug; Female; Histamine; Histamine N-Methyltransferase; Humans; Liver; Male; Middle Aged; Stereoisomerism | 1994 |
The effects of chronic administration of chloroquine and quinacrine on the response of normal and denervated smooth muscle to agonist drugs.
Topics: Acetylcholine; Age Factors; Animals; Atropine; Chickens; Chloroquine; Culture Techniques; Dose-Response Relationship, Drug; Histamine; Male; Muscle, Smooth; Neurotransmitter Agents; Norepinephrine; Potassium Chloride; Pyrilamine; Quinacrine; Serotonin; Synaptic Transmission | 1993 |
Chloroquine-induced venodilation in human hand veins.
Topics: Adult; Antimalarials; Antirheumatic Agents; Chloroquine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hand; Histamine; Histamine Antagonists; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vasodilation; Veins | 1997 |
Interaction of local anaesthetics with histamine H1 receptors in guinea-pig ileum.
Topics: Anesthetics, Local; Animals; Binding, Competitive; Chloroquine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Isotope Labeling; Male; Muscle Contraction; Muscle, Smooth; Procaine; Pyrilamine; Quinacrine; Receptors, Histamine H1; Structure-Activity Relationship; Tetracaine | 1997 |
Increased plasma levels of histidine and histamine in falciparum malaria: relevance to severity of infection.
Topics: Amino Acids; Antimalarials; Blood-Brain Barrier; Brain; Child; Child, Preschool; Chloroquine; Female; Histamine; Histidine; Humans; Infant; Kinetics; Malaria, Falciparum; Male; Phenylalanine; Prospective Studies; Reference Values; Severity of Illness Index | 2000 |
Antimalarial activities of ring-substituted bioimidazoles.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Histamine; Histidine; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Mice; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship | 2002 |
[PROTECTIVE SERUMS IN COMBINATION WITH CORTICOIDS AND GAMMA GLOBULINS].
Topics: Adrenal Cortex Hormones; Anti-Allergic Agents; Asthma; Chloroquine; gamma-Globulins; Histamine; Histamine H1 Antagonists; Humans; Immune Sera; Immunization, Passive | 1963 |
ANTIHISTAMINIC ACTION OF ANTIMALARIALS.
Topics: Acetylcholine; Animals; Antimalarials; Blood Pressure; Blood Pressure Determination; Capillary Permeability; Chloroquine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Muscle, Smooth; Pharmacology; Quinacrine; Quinine; Research | 1963 |
Influence of genotype, dose and sex on pruritogen-induced scratching behavior in the mouse.
Topics: Analysis of Variance; Animals; Behavior, Animal; Chloroquine; Dose-Response Relationship, Drug; Female; Genotype; Histamine; Injections, Subcutaneous; Irritants; Male; Mice; Mice, Inbred Strains; Pruritus; Sex Characteristics; Species Specificity | 2006 |
Ligation of Toll-like receptor 3 differentially regulates M2 and M3 muscarinic receptor expression and function in human airway smooth muscle cells.
Topics: 2-Aminopurine; Bronchial Hyperreactivity; Calcium Signaling; Cells, Cultured; Chloroquine; Colforsin; Cyclic AMP; eIF-2 Kinase; Gene Expression Regulation; Histamine; Humans; Leukotriene D4; Membrane Proteins; Muscarinic Antagonists; Myocytes, Smooth Muscle; Poly I-C; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Histamine H1; Receptors, Leukotriene; Signal Transduction; Toll-Like Receptor 3 | 2008 |
Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.
Topics: Animals; Capsaicin; Chloroquine; Ganglia, Spinal; Histamine; Humans; Mice; Pruritus; Receptors, G-Protein-Coupled; Sensory Receptor Cells | 2009 |
Antipruritic activity of extracts of Humulus scandens, the combinations of bioactive flavonoids.
Topics: 4-Aminopyridine; Animals; Antipruritics; Chloroquine; Dexamethasone; Flavonoids; Histamine; Humulus; Mast Cells; Mice; Mice, Inbred ICR; Peritoneum; Pruritus; Rats | 2010 |
Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons.
Topics: Aminoquinolines; Animals; Chloroquine; Histamine; Imiquimod; Interferon Inducers; Mice; Neurons; Pruritus; TRPV Cation Channels | 2011 |
TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antirheumatic Agents; Calcium; Capsaicin; Cells, Cultured; Chloroquine; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Histamine; Membrane Potentials; Mice; Mice, Knockout; Mustard Plant; Neuroblastoma; Patch-Clamp Techniques; Peptides; Plant Oils; Pruritus; Receptors, G-Protein-Coupled; Sensory Receptor Cells; Signal Transduction; Time Factors; Transfection; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2011 |
Spinal bombesin-recognized neurones mediate more nonhistaminergic than histaminergic sensation of itch in mice.
Topics: Animals; Bombesin; Chloroquine; Denervation; Histamine; Histamine Agonists; Hypersensitivity; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Pruritus; Receptors, Bombesin; Ribosome Inactivating Proteins, Type 1; Saporins; Skin; Synaptic Transmission | 2012 |
CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch.
Topics: Animals; Brain; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Chloroquine; Female; Ganglia, Spinal; Green Fluorescent Proteins; Histamine; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Muscles; Mustard Plant; Pain; Plant Oils; Posterior Horn Cells; Pruritus; Sensory Receptor Cells; Skin; TRPM Cation Channels; TRPV Cation Channels | 2012 |
Site-dependent and state-dependent inhibition of pruritogen-responsive spinal neurons by scratching.
Topics: Animals; Capsaicin; Chloroquine; Evoked Potentials; Histamine; Male; Mice; Mice, Inbred C57BL; Posterior Horn Cells; Pruritus; Reflex; Touch | 2012 |
Development and validation of an automated system for detection and assessment of scratching in the rodent.
Topics: Algorithms; Analog-Digital Conversion; Animals; Anti-Allergic Agents; Automation; Behavior, Animal; Chloroquine; Data Interpretation, Statistical; Diphenhydramine; Electromagnetic Fields; Foot; Histamine; Male; Mice; Mice, Inbred C57BL; Motion; p-Methoxy-N-methylphenethylamine; Pruritus; Psychology, Experimental; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Signal Processing, Computer-Assisted | 2012 |
Cross-sensitization of histamine-independent itch in mouse primary sensory neurons.
Topics: Animals; Behavior, Animal; Calcium Signaling; Chloroquine; Ganglia, Spinal; Histamine; Male; Mice; Mice, Inbred C57BL; Neuroimaging; Peptide Fragments; Pruritus; Receptor, PAR-2; Sensory Receptor Cells; Signal Transduction | 2012 |
Roles for substance P and gastrin-releasing peptide as neurotransmitters released by primary afferent pruriceptors.
Topics: Animals; Calcium; Chloroquine; Ganglia, Spinal; Gastrin-Releasing Peptide; Histamine; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Oligopeptides; Peptide Fragments; Pruritus; Receptors, Bombesin; Sensory Receptor Cells; Serotonin; Signal Transduction; Substance P | 2013 |
A subpopulation of nociceptors specifically linked to itch.
Topics: Action Potentials; Animals; Antirheumatic Agents; Calcium; Capsaicin; Cells, Cultured; Chloroquine; Epidermis; Ganglia, Spinal; Gene Expression Regulation; Green Fluorescent Proteins; Histamine; Hot Temperature; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Fibers; Nerve Tissue Proteins; Nociceptors; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Peptide Fragments; Plant Lectins; Proteins; Proto-Oncogene Proteins c-fos; Pruritus; Receptors, Bombesin; Receptors, G-Protein-Coupled; RNA, Untranslated; Rotarod Performance Test; Sensory Receptor Cells; Sensory System Agents; Spinal Cord; TRPV Cation Channels | 2013 |
Itch and analgesia resulting from intrathecal application of morphine: contrasting effects on different populations of trigeminothalamic tract neurons.
Topics: Action Potentials; Analgesics, Opioid; Animals; Antirheumatic Agents; Chloroquine; Electric Stimulation; Histamine; Injections, Spinal; Male; Morphine; Neural Pathways; Pain; Peptide Fragments; Pruritus; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin; Stimulation, Chemical; Thalamus; Trigeminal Nuclei | 2013 |
Assessment of pain and itch behavior in a mouse model of neurofibromatosis type 1.
Topics: Animals; Capsaicin; Chloroquine; Constriction; Disease Models, Animal; Functional Laterality; Histamine; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurofibromatosis 1; p-Methoxy-N-methylphenethylamine; Pain; Pain Measurement; Pain Threshold; Pruritus | 2013 |
The cells and circuitry for itch responses in mice.
Topics: Animals; Chloroquine; Endothelin-1; Gastrin-Releasing Peptide; Histamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Natriuretic Peptide, Brain; Nociception; Phospholipase C beta; Pruritus; Receptors, Atrial Natriuretic Factor; Sensory Receptor Cells; Spinal Cord; TRPV Cation Channels | 2013 |
Extracellular signal-regulated kinase (ERK) activation is required for itch sensation in the spinal cord.
Topics: Animals; Butadienes; Chloroquine; Dinitrofluorobenzene; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Histamine; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Neuroglia; Nitriles; Oligopeptides; Phosphorylation; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Pruritus; Receptors, Histamine H1; Sensation; Spinal Cord; Time Factors | 2014 |
Bitter taste receptor (TAS2R) agonists inhibit IgE-dependent mast cell activation.
Topics: Chloroquine; Dextromethorphan; Fetal Blood; Gene Expression Regulation; Histamine; Humans; Immunoglobulin E; Mast Cells; Noscapine; Prostaglandin D2; Protein Isoforms; Quaternary Ammonium Compounds; Receptors, G-Protein-Coupled; Receptors, IgE | 2014 |
Nalfurafine suppresses pruritogen- and touch-evoked scratching behavior in models of acute and chronic itch in mice.
Topics: Animals; Antipruritics; Behavior, Animal; Chloroquine; Disease Models, Animal; Histamine; Ichthyosis; Male; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; Morphinans; Pressure; Pruritus; Skin; Spiro Compounds; Time Factors | 2015 |
Human sensory neurons: Membrane properties and sensitization by inflammatory mediators.
Topics: Action Potentials; Adenosine Triphosphate; Adolescent; Bradykinin; Capsaicin; Cell Membrane; Chloroquine; Dinoprostone; Female; Ganglia, Spinal; Histamine; Humans; Male; Patch-Clamp Techniques; Sensory Receptor Cells; Young Adult | 2014 |
Role of spinal bombesin-responsive neurons in nonhistaminergic itch.
Topics: Animals; Bombesin; Capsaicin; Chloroquine; Histamine; Hot Temperature; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Peptide Fragments; Posterior Horn Cells; Pruritus; Touch | 2014 |
TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity.
Topics: Animals; Calcium; Capsaicin; Chloroquine; HEK293 Cells; Histamine; Humans; Intracellular Space; Ion Channel Gating; Mice, Inbred C57BL; Mice, Knockout; Pruritus; Receptors, Histamine; Sensory Receptor Cells; Toll-Like Receptor 4; TRPV Cation Channels | 2014 |
Response characteristics of pruriceptive and nociceptive trigeminoparabrachial tract neurons in the rat.
Topics: Action Potentials; Animals; beta-Alanine; Capsaicin; Cheek; Chloroquine; Histamine; Hot Temperature; Male; Mustard Plant; Neural Pathways; Nociceptive Pain; Parabrachial Nucleus; Physical Stimulation; Plant Oils; Pruritus; Rats, Sprague-Dawley; Sensory Receptor Cells; Serotonin; Touch; Trigeminal Nerve | 2015 |
Protein kinase Cδ mediates histamine-evoked itch and responses in pruriceptors.
Topics: Animals; beta-Alanine; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cells, Cultured; Chloroquine; Disease Models, Animal; Down-Regulation; Ganglia, Spinal; Histamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Kinase C-alpha; Pruritus; Sensory Receptor Cells; TRPV Cation Channels | 2015 |
Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice.
Topics: Animals; Behavior, Animal; Caffeic Acids; Chloroquine; HEK293 Cells; Histamine; Humans; Menthol; Mice; Oligopeptides; Pruritus; Receptor, PAR-2; Receptors, G-Protein-Coupled; Receptors, Histamine H1; Sensory Receptor Cells; Synaptic Transmission; TRPM Cation Channels; TRPV Cation Channels | 2015 |
Anatomical evidence of pruriceptive trigeminothalamic and trigeminoparabrachial projection neurons in mice.
Topics: Animals; Antipruritics; Brain Mapping; Capsaicin; Chloroquine; Histamine; Histamine Agonists; Male; Mice; Mice, Inbred C57BL; Neurons; Oncogene Proteins v-fos; Parabrachial Nucleus; Posterior Horn Cells; Stilbamidines; Thalamus; Trigeminal Nucleus, Spinal | 2016 |
Pleiotropic Effects of Bitter Taste Receptors on [Ca2+]i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells.
Topics: Action Potentials; Aristolochic Acids; Calcium Signaling; Cells, Cultured; Chloroquine; Endothelin-1; Genetic Pleiotropy; Histamine; Humans; Lung; Muscle Relaxation; Myocytes, Smooth Muscle; Receptors, G-Protein-Coupled; Receptors, Histamine | 2015 |
Electrophysiological properties of brain-natriuretic peptide- and gastrin-releasing peptide-responsive dorsal horn neurons in spinal itch transmission.
Topics: Action Potentials; Animals; Chloroquine; Gastrin-Releasing Peptide; Histamine; Male; Mice; Mice, Inbred C57BL; Natriuretic Peptide, Brain; Posterior Horn Cells; Pruritus | 2016 |
Mechanisms of pruritogen-induced activation of itch nerves in isolated mouse skin.
Topics: Action Potentials; Animals; Anoctamin-1; Chloroquine; Histamine; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Phospholipase C beta; Pruritus; Skin; TRPA1 Cation Channel | 2017 |
Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons.
Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Chloroquine; Chronic Disease; Cryotherapy; Disease Models, Animal; Histamine; Humans; Menthol; Mice; Mice, Inbred C57BL; Mice, Knockout; Pruritus; Sensory Receptor Cells; Skin; Treatment Outcome; TRPM Cation Channels | 2018 |
GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way.
Topics: Animals; Cell Line; Chloroquine; Dermatitis, Contact; Dinitrochlorobenzene; Disease Models, Animal; Female; G-Protein-Coupled Receptor Kinase 2; Ganglia, Spinal; Gene Knockdown Techniques; Glutamine; Histamine; Humans; Injections, Subcutaneous; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; Pruritus; Rats; RNA, Small Interfering | 2018 |
Responses of thalamic neurons to itch- and pain-producing stimuli in rats.
Topics: Action Potentials; Animals; Antipruritics; beta-Alanine; Capsaicin; Chloroquine; Histamine; Injections, Intradermal; Male; Neurons; Neurotransmitter Agents; Pain; Poisson Distribution; Pruritus; Rats; Rats, Sprague-Dawley; Serotonin; Ventral Thalamic Nuclei | 2018 |
Effects of pruritogens and algogens on rostral ventromedial medullary ON and OFF cells.
Topics: Animals; Capsaicin; Chloroquine; Evoked Potentials; Hindlimb; Histamine; Male; Medulla Oblongata; Mice; Mice, Inbred C57BL; Neurons, Afferent; Nociception; Pruritus; Reflex; Touch | 2018 |
The behavioral study on the interactive aggravation between pruritus and depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Chloroquine; Depression; Depressive Disorder; Disease Models, Animal; Histamine; Histamine Agonists; Ketamine; Male; Mice; Pruritus; Treatment Outcome | 2018 |
A Subpopulation of Amygdala Neurons Mediates the Affective Component of Itch.
Topics: Amygdala; Animals; Avoidance Learning; Chloroquine; Female; Histamine; Male; Mice; Mice, Inbred C57BL; Neurons; Optogenetics; Pruritus; Serotonin | 2019 |
Serotoninergic projection from dorsal raphe nucleus to insular cortex is involved in acute itch sensation processing in mice.
Topics: Animals; Brain Stem; Cerebral Cortex; Chloroquine; Dorsal Raphe Nucleus; Histamine; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neurons; Pruritus; Serotonin | 2019 |
Central Processing of Itch in the Midbrain Reward Center.
Topics: Animals; Behavior, Animal; Calcium Signaling; Chloroquine; Dopaminergic Neurons; Electrophysiological Phenomena; GABAergic Neurons; Histamine; Histamine Agonists; Mesencephalon; Mice; Optogenetics; Pruritus; Reward; Ventral Tegmental Area | 2019 |
Signal Transducer and Activator of Transcription 3 in Keratinocytes Regulates Histaminergic Itch but Not Nonhistaminergic Itch.
Topics: Animals; Chloroquine; Disease Models, Animal; Female; Histamine; Keratinocytes; Male; Mice, Knockout; Pruritus; Serotonin; Signal Transduction; STAT3 Transcription Factor; TRPV Cation Channels | 2019 |
Calcium imaging of primary canine sensory neurons: Small-diameter neurons responsive to pruritogens and algogens.
Topics: Animals; Cadaver; Calcium Radioisotopes; Capsaicin; Cattle; Cells, Cultured; Chloroquine; Dogs; Ganglia, Spinal; Histamine; Humans; Laminectomy; Molecular Imaging; Neurotransmitter Agents; Pain; Peptide Fragments; Pruritus; Radiopharmaceuticals; Sensory Receptor Cells; Serotonin; Serotonin Receptor Agonists; Substance P | 2019 |
Pharmacological characteristics of hemokinin-1-derived peptides in rat pruriceptive processing.
Topics: Administration, Intranasal; Animals; Behavior, Animal; Chloroquine; Dose-Response Relationship, Drug; Histamine; Injections, Spinal; Male; Peptide Fragments; Pruritus; Rats, Sprague-Dawley; Tachykinins | 2020 |
Bulleyaconitine A Inhibits Itch and Itch Sensitization Induced by Histamine and Chloroquine.
Topics: Aconitine; Animals; China; Chloroquine; Histamine; Mice; Posterior Horn Cells; Pruritus; Quality of Life; Rats | 2020 |
Hippocalcin-like 4, a neural calcium sensor, has a limited contribution to pain and itch processing.
Topics: Animals; Behavior Rating Scale; Behavior, Animal; Chloroquine; Gene Knockout Techniques; Histamine; Hot Temperature; Interneurons; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurocalcin; Pain; Pruritus; Sciatic Nerve; Spinal Cord Dorsal Horn | 2020 |
Cav3.2 T-type calcium channels control acute itch in mice.
Topics: Acute Disease; Animals; Behavior, Animal; Calcium Channels, T-Type; Chloroquine; Female; Histamine; Male; Mice, Inbred C57BL; Pruritus | 2020 |
IL-23 modulates histamine-evoked itch and responses of pruriceptors in mice.
Topics: Animals; Behavior, Animal; Calcium; Cells, Cultured; Chloroquine; Ganglia, Spinal; Histamine; Interleukin-17; Interleukin-22; Interleukin-23; Interleukins; Male; Mice; Neurons; Pruritus | 2020 |
Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice.
Topics: Animals; Behavior, Animal; Chloroquine; Cyclopropanes; Disease Models, Animal; Histamine; Hypodermoclysis; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Nitriles; Pruritus; Pyridones; Quinoxalines; Receptors, AMPA | 2020 |
Ethosuximide inhibits acute histamine- and chloroquine-induced scratching behavior in mice.
Topics: Animals; Behavior, Animal; Chloroquine; Ethosuximide; Female; Histamine; Male; Mice, Inbred C57BL; Pruritus | 2021 |
Oxymatrine screened from Sophora flavescens by cell membrane immobilized chromatography relieves histamine-independent itch.
Topics: Alkaloids; Animals; Antipruritics; Cell Membrane; Chloroquine; Chromatography; Disease Models, Animal; Drug Discovery; Ganglia, Spinal; Histamine; Humans; Isothiocyanates; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Oligopeptides; Phytotherapy; Plant Extracts; Pruritus; Quinolizines; RNA, Messenger; Sophora; TRPA1 Cation Channel | 2021 |
Berbamine Reduces Chloroquine-Induced Itch in Mice through Inhibition of MrgprX1.
Topics: Animals; Benzylisoquinolines; Chloroquine; Histamine; Mice; Pruritus; Ubiquitin-Protein Ligases | 2022 |
Microglia are involved in regulating histamine-dependent and non-dependent itch transmissions with distinguished signal pathways.
Topics: Animals; Chloroquine; Histamine; Mice; Mice, Transgenic; Microglia; Pain; Pruritus; Signal Transduction | 2023 |
Role of kainate receptors in pruriceptive processing in the mouse spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chloroquine; Excitatory Amino Acid Antagonists; Glutamic Acid; Histamine; Mammals; Mice; Pruritus; Receptors, Kainic Acid; RNA, Small Interfering; Spinal Cord | 2023 |
Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis.
Topics: Animals; Calcium; Capsaicin; Chloroquine; Dermatitis, Atopic; Disease Models, Animal; Histamine; Neutrophil Infiltration; Pain; Pruritus | 2023 |
An atlas of itch-associated neural dynamics in the mouse brain.
Topics: Animals; Brain; Chloroquine; Histamine; Mice; Pruritus | 2023 |