chloroquine and halofantrine

chloroquine has been researched along with halofantrine in 109 studies

Research

Studies (109)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (10.09)	18.7374
1990's	68 (62.39)	18.2507
2000's	21 (19.27)	29.6817
2010's	9 (8.26)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jomaa, H; Mitsch, A; Schlitzer, M; Wiesner, J; Wissner, P	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Malik, H; Puri, SK; Singh, C	1
Egan, TJ; Hoppe, HC; Joiner, KA; Roberts, L	1
Bambal, RB; Bates, M; Berry, N; Biagini, GA; Bonar-Law, R; Bray, PG; Brigandi, RA; Davis, CB; Gargallo, DV; Gibbons, P; Gomez-delas-Heras, FM; Gresham, SL; Hart, TK; Hindley, S; Lawrence, RM; Maggs, JL; Mukhtar, A; O'Neill, PM; Park, BK; Roberts, P; Shone, AE; Stocks, PA; Ward, SA; Winstanley, PA	1
Masseno, V; Muriithi, S; Nzila, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Sen, S; Sinha, N	1
Abla, N; Besson, D; Bombrun, A; Brun, R; Burt, H; Georgi, K; Kaiser, M; Molette, J; Muzerelle, M; Nwaka, S; Routier, J; Scheer, A	1
Caridha, D; Gerena, L; Korotchenko, V; Kreishman-Deitrick, M; Li, Q; Lin, AJ; Sathunuru, R; Smith, PL	1
Avery, VM; Buchholz, M; Delves, MJ; Duffy, S; Fischli, C; Held, J; Knaab, TC; Kuna, K; Kurz, T; Lehmann, U; Leven, M; Lungerich, B; Meister, S; Meitzner, D; Mordmüller, B; Stahlke, P; Winzeler, EA; Wittlin, S	1
Baudon, D; Bernard, J; Lantrade, P; Martet, G; Mouliat-Pelat, JP; Picq, JJ; Sarrouy, J; Spiegel, A; Touzé, JE	1
Badoual, J	1
Chutmongkonkul, M; Maier, WA; Seitz, HM	2
Basco, LK; Le Bras, J	3
Fadat, G; Gardon, J; Gazin, P; Hengy, C; Jambou, R; Louis, FJ; Louis, JP; Trebucq, A	1
Bustos, MD; Ciceron, L; Danis, M; Gay, F; Gentilini, M; Pichet, C; Rojas-Rivero, L	1
Bauchet, J; Hatin, I; Le Bras, J; Legros, F; Trape, JF	1
Basco, LK; Bouchaud, O; Coulaud, JP; Farinotti, R; Gillotin, C; Gimenez, F; Le Bras, J; Rabenjarson, E; Ringwald, P	1
Kidson, C	1
Baudon, D; Cordoliani, G; Da Conceicao, S; Delolme, H; Doury, JC; Hovette, P; Lecamus, JL; Martet, G; Raphenon, G; Touze, JE	1
Trigg, PI	1
Abila, B; Ambakederemo, AW; Ezeamuzie, IC; Igbigbi, PS; Nwaejike, IN	1
Bourdeau, EF; Childs, GE; Milhous, WK; Pang, L; Wimonwattratee, T	1
Le Bras, M; Mazaudier, E; Raccurt, CP; Ripert, C; Schmitt, A	1
Becker, JM; Bernard, J; Dupasquier, I; Geffray, L; Gimenez, M; Jourdan, G; Lesbordes, JL; Molinas, JM; Sarrouy, J	1
Bustos, MD; Danis, M; Diquet, B; Félix, R; Gay, F; Gentilini, M; Lyogoubi, A	1
Rooney, W; Schildbach, S; Suebsaeng, L; Wernsdorfer, WH	1
Bustos, D; Caumes, E; Danis, M; Datry, A; Diquet, B; Gay, F; Gentilini, M; Litaudon, M	1
Salako, LA; Sowunmi, A; Walker, O	1
Hallwood, PM; Horton, RJ; O'Sullivan, KM; Parr, SN	1
Gilles, HM; Kariuki, D; Koech, DK; Lury, JD; Mjomba, M; Mosoba, M; Oloo, JA; Watkins, WM	1
Gilles, HM; Khoromana, C; Molyneux, ME; Wirima, J	1
Chanthavanich, P; Karbwang, J; Looareesuwan, S; Phillips, RE; Supanaranond, W; Turner, RC; Warrell, DA; White, NJ	1
Childs, GE; Pooyindee, N; Wimonwattrawatee, T	1
Boudreau, EF; Pang, LW; Pavanand, K; Webster, HK; Yongvanitchit, K	1
Canfield, CJ; Cosgriff, TM; Pamplin, CL; Willet, GP	1
Coulanges, P; Deloron, P; Le Bras, J; Ramanamirija, JA	1
Biaud, JM; Coulanges, P; Deloron, P; Le Bras, J; Ramanamirija, JA	1
Coulanges, P; Coulaud, JP; Deloron, P; Le Bras, J	1
Fasanmade, AA; Jusko, WJ	1
Bray, PG; Hawley, SR; Mungthin, M; Ward, SA	1
Eichenlaub, D; Jelinek, T; Löscher, T; Schelbert, P	1
Sorabjee, JS	1
Baird, JK; Basri, H; Fryauff, DJ; Hoffman, SL; Leksana, B; Masbar, S; McElroy, PD; Richie, TL; Subianto, B; Wignall, FS	1
Basco, LK; Le Bras, J; Makler, MM; Marquet, F	1
Edwards, G; Ward, SA; Winstanley, PA	1
Baric, RS; Bright, P; Handy, J; Peel, SA; Yount, B	1
Bienzle, U; Graninger, W; Jenne, L; Kremsner, PG; Wildling, E	2
Basco, LK; Le Bras, J; Ramiliarisoa, O	1
Gazin, PP	1
Edstein, MD; Kereu, RK; Rieckmann, KH; Shanks, GD; Spicer, PE	1
Howells, RE; Nateghpour, M; Ward, SA	1
Bougouma, L; Del Nero, L; Lamizana, L; Nebie, I; Pietra, V; Sare, S	1
Baric, RS; Handy, J; Merritt, SC; Peel, SA	1
Gerena, L; Karle, JM; Milhous, WK; Olmeda, R	1
Mharakurwa, S	1
Basco, LK; de Pecoulas, PE; Le Bras, J; Wilson, CM	1
Anabwani, GM; Esamai, FO; Menya, DA	1
Abecassis, L; Adam, MN; Baledent, F; Caillet, R; Giacomini, T; Le Bras, J; Poupin, F	1
Ezedinachi, E	1
Bray, PG; Green, JE; Hawley, SR; Mungthin, M; Ritchie, GY; Ward, SA	1
Baird, JK; Bangs, MJ; Basri, H; Fryauff, DJ; Harjosuwarno, S; Hoffman, SL; Richie, TL; Subianto, B; Tjitra, E; Wiady, I	1
Fleck, SL; Peters, W; Robinson, BL	1
Hartwell, LH; Sibley, CH; Vasquez, B; Wooden, JM	1
Falade, CO; Fehintola, FA; Kyle, DE; Makler, MT; Milhous, WK; Oduola, AM; Ogundahunsi, OA; Omitowoju, GO; Piper, RC; Schuster, BG; Sowunmi, A	1
Charman, WN; Cowman, AF; Horton, J; Humberstone, AJ	1
Boele van Hensbroek, M; Kager, PA; Wetsteyn, JC; Zijlmans, CW	1
Doury, JC; Fusai, T; Pradines, B; Rogier, C; Tall, A; Trape, JF	1
Kremsner, PG; Philipps, J; Radloff, PD; Wernsdorfer, W	1
Coulibaly, SO; Dutheil, Y; Guiguemdé, TR; Ouédraogo, JB; Tall, F; Tinto, H; Traoré, B; Zampa, H	1
Bray, PG; Mungthin, M; Ridley, RG; Ward, SA	1
Doury, JC; Kombila, M; Lebeau, C; Mabika Mamfoumbi, M; Mourou Mbina, JR; Owono Medang, M; Parzy, D; Pradines, B	2
Bourgeade, A; Delmont, J	1
Burgel, PR; Camara, P; Hovette, P; Klotz, F; Mbaye, PS; Sane, M	1
Le Bras, J	1
Bray, PG; Mungthin, M; Ward, SA	1
Lial, JP	1
Danis, M; Delhaes, L; Gay, F; Lazaro, JE; Thellier, M	1
Basco, LK; Ringwald, P	1
Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC	1
Caruana, SR; Cowman, AF; Kirk, K; Reed, MB; Saliba, KJ	1
Makonnen, E; Mengesha, T	1
Lennard, MS; Sijumbil, G; Simooya, OO; Tucker, GT	1
Hombhanje, FW	1
Adamu, A; Agbonlahor, DE; Dalyop, P; Elesha, SO; Fagbenro-Beyioku, AF; Ogunbanwo, JA	1
Aggarwal, P; Biswas, A; Handa, R; Suresh, V; Wali, JP; Wig, N	1
Baird, JK; Doan, HN; Fryauff, DJ; Gómez-Saladín, E; Kain, KC; Le, DC; Nguyen, DT; Taylor, WR; Tran, TU	1
Granier, H; Klotz, F; Martin, J; Nicolas, X	1
Beytout, J; Caumon, L; Chouaki, M; Cueto, T; Delort, P; Dufraise, S; Monchard, F; Philippe, JM; Rimeize, H	1
Atteke, C; Aubouy, A; Bakary, M; Deloron, P; Lébibi, J; Ndong, JM	1
Angles, A; Bagheri, H; Magnaval, JF; Montastruc, JL	1
Jambou, R; Randrianarijaona, A; Randrianarivelojosia, M; Randrianasolo, L; Ratsimbasoa, A	1
Hayton, K; Su, XZ	1
Brown, ML; Geyer, JA; Terrell, JC; Trotta, RF	1
Beg, MA; Khan, MA; Razi, ST; Smego, RA	1
Bray, PG; Fidock, DA; Johnson, DJ; Lakshmanan, V; Mungthin, M; Sidhu, AB; Ward, SA	1
Brockman, A; Chotivanich, K; Day, NP; Stepniewska, K; White, NJ	1
Abuaku, B; Duah, NO; Koram, KA; Quashie, NB	1
Adewunmi, CO; Agbedahunsi, JM; Ijarotimi, SO; Onyeji, CO	1
Berger, F; Bertani, S; Bouchier, C; Ekala, MT; Legrand, E; Mercereau-Puijalon, O; Meynard, JB; Musset, L; Péneau, J; Volney, B; Yrinesi, J	1
Al-Farsi, HM; Al-Hashami, ZS; Al-Qahtani, A; Al-Sheikh, AA; Babiker, HA; Bin Dajem, SM	1
Clark, J; Golenser, J; Guiguemde, WA; Guo, J; Guy, RK; Haynes, RK; Hunt, NH; Marciano, A	1

Reviews

6 review(s) available for chloroquine and halofantrine

Article	Year
Clinical pharmacokinetics in the treatment of tropical diseases. Some applications and limitations. Clinical pharmacokinetics, 1994, Volume: 27, Issue:2 Topics: Chloroquine; Diethylcarbamazine; Drug Resistance; Echinococcosis; Filariasis; Humans; Malaria; Mefloquine; Pharmacokinetics; Phenanthrenes; Pyrimethamine; Quinine; Sulfadoxine; Tropical Medicine	1994
[The treatment of malaria]. Nederlands tijdschrift voor geneeskunde, 1997, Sep-13, Volume: 141, Issue:37 Topics: Adult; Antimalarials; Chloroquine; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Pregnancy; Primaquine	1997
Comparative efficacy and safety of chloroquine and alternative antimalarial drugs: a meta-analysis from six African countries. East African medical journal, 1999, Volume: 76, Issue:6 Topics: Africa, Eastern; Africa, Western; Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Costs; Humans; Malaria; Mefloquine; Patient Selection; Phenanthrenes; Pyrimethamine; Quinine; Safety; Sulfadoxine; Treatment Outcome	1999
[Epidemiological and therapeutic aspects of plasmodial infection from Plasmodium vivax]. Medecine tropicale : revue du Corps de sante colonial, 2000, Volume: 60, Issue:4 Topics: Antimalarials; Chloroquine; Clinical Protocols; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Malaria, Vivax; Phenanthrenes; Primaquine; Recurrence; Risk Factors; Treatment Outcome	2000
Genetic and biochemical aspects of drug resistance in malaria parasites. Current drug targets. Infectious disorders, 2004, Volume: 4, Issue:1 Topics: Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; Drug Resistance; Drug Resistance, Multiple; Humans; Linkage Disequilibrium; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Mutation; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase	2004
Emerging drug--resistance and guidelines for treatment of malaria. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2004, Volume: 14, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Pakistan; Phenanthrenes; Plasmodium falciparum; Quinidine; Quinine; Sesquiterpenes; Time Factors	2004

Trials

16 trial(s) available for chloroquine and halofantrine

Article	Year
[Efficacy of radical treatment with halofantrine on the prevention of imported Plasmodium falciparum malaria]. Annales de la Societe belge de medecine tropicale, 1992, Volume: 72, Issue:4 Topics: Adult; Antimalarials; Chloroquine; Humans; Malaria, Falciparum; Male; Military Personnel; Phenanthrenes	1992
Halofantrine-induced pruritus amongst subjects who itch to chloroquine. The Journal of tropical medicine and hygiene, 1991, Volume: 94, Issue:3 Topics: Acute Disease; Adolescent; Adult; Antimalarials; Chloroquine; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Kinetics; Malaria; Male; Middle Aged; Pain Measurement; Phenanthrenes; Pruritus	1991
Pruritus and antimalarial drugs in Africans. Lancet (London, England), 1989, Jul-22, Volume: 2, Issue:8656 Topics: Antimalarials; Chloroquine; Humans; Nigeria; Phenanthrenes; Pruritus	1989
Efficacy of multiple-dose halofantrine in treatment of chloroquine-resistant falciparum malaria in children in Kenya. Lancet (London, England), 1988, Jul-30, Volume: 2, Issue:8605 Topics: Administration, Oral; Adolescent; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Resistance; Female; Follow-Up Studies; Half-Life; Humans; Infant; Kenya; Malaria; Male; Phenanthrenes; Plasmodium falciparum; Time Factors	1988
Clinical trials with halofantrine hydrochloride in Malawi. Lancet (London, England), 1988, Jul-30, Volume: 2, Issue:8605 Topics: Administration, Oral; Adolescent; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Female; Follow-Up Studies; Humans; Infant; Malaria; Malawi; Male; Phenanthrenes; Plasmodium falciparum; Recurrence; Time Factors	1988
Treatment of chloroquine-resistant Plasmodium vivax with chloroquine and primaquine or halofantrine. The Journal of infectious diseases, 1995, Volume: 171, Issue:6 Topics: Adolescent; Animals; Child; Chloroquine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Vivax; Male; Middle Aged; Phenanthrenes; Plasmodium vivax; Primaquine	1995
Comparison of micronized halofantrine with chloroquine-antibiotic combinations for treating Plasmodium falciparum malaria in adults from Gabon. The American journal of tropical medicine and hygiene, 1994, Volume: 50, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Aged; Antimalarials; Chloroquine; Clindamycin; Doxycycline; Drug Therapy, Combination; Female; Follow-Up Studies; Gabon; Humans; Malaria, Falciparum; Male; Middle Aged; Phenanthrenes	1994
High dose chloroquine versus micronized halofantrine in chloroquine-resistant Plasmodium falciparum malaria. The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:4 Topics: Adolescent; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Phenanthrenes	1994
Postexposure administration of halofantrine for the prevention of malaria. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 17, Issue:4 Topics: Administration, Oral; Adult; Antimalarials; Chloroquine; Drug Administration Schedule; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Papua New Guinea; Phenanthrenes; Travel	1993
In vivo sensitivity of Plasmodium falciparum to halofantrine hydrochloride in Burkina Faso. The American journal of tropical medicine and hygiene, 1994, Volume: 50, Issue:1 Topics: Alanine Transaminase; Animals; Antimalarials; Aspartate Aminotransferases; Bilirubin; Burkina Faso; Child; Child, Preschool; Chloroquine; Creatinine; Drug Resistance; Female; Follow-Up Studies; Hematocrit; Hemoglobins; Humans; Leukocyte Count; Malaria, Falciparum; Male; Phenanthrenes; Plasmodium falciparum	1994
A randomised controlled trial to assess the relative efficacy of chloroquine, amodiaquine, halofantrine and Fansidar in the treatment of uncomplicated malaria in children. East African medical journal, 1996, Volume: 73, Issue:3 Topics: Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Phenanthrenes; Pyrimethamine; Sulfadoxine; Treatment Outcome	1996
In vivo efficacy of chloroquine, halofantrine, pyrimethamine-sulfadoxine and qinghaosu (artesunate) in the treatment of malaria in Calabar, Nigeria. The Central African journal of medicine, 1996, Volume: 42, Issue:4 Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Nigeria; Phenanthrenes; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Time Factors; Urban Health	1996
Halofantrine and primaquine for radical cure of malaria in Irian Jaya, Indonesia. Annals of tropical medicine and parasitology, 1997, Volume: 91, Issue:1 Topics: Adult; Antimalarials; Chloroquine; Drug Therapy, Combination; Follow-Up Studies; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Male; Parasitemia; Phenanthrenes; Primaquine; Recurrence; Treatment Outcome	1997
Molecular epidemiology of malaria in Yaounde, Cameroon V. analysis of the omega repetitive region of the plasmodium falciparum CG2 gene and chloroquine resistance. The American journal of tropical medicine and hygiene, 1999, Volume: 61, Issue:5 Topics: Adolescent; Adult; Animals; Antimalarials; Cameroon; Child; Chloroquine; DNA Primers; DNA, Protozoan; Drug Resistance; Electrophoresis, Agar Gel; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Naphthyridines; Parasitemia; Phenanthrenes; Plasmodium falciparum; Polymerase Chain Reaction; Regression Analysis; Repetitive Sequences, Nucleic Acid; Scintillation Counting; Sequence Analysis, DNA	1999
Halofantrine and chloroquine inhibit CYP2D6 activity in healthy Zambians. British journal of clinical pharmacology, 1998, Volume: 45, Issue:3 Topics: Administration, Oral; Adult; Antimalarials; Black People; Chloroquine; Chromatography, Gas; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Humans; Liver; Male; Phenanthrenes; Zambia	1998
Assessing drug sensitivity of Plasmodium vivax to halofantrine or choroquine in southern, central Vietnam using an extended 28-day in vivo test and polymerase chain reaction genotyping. The American journal of tropical medicine and hygiene, 2000, Volume: 62, Issue:6 Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Genotype; Humans; Malaria, Vivax; Male; Merozoite Surface Protein 1; Middle Aged; Phenanthrenes; Plasmodium vivax; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Vietnam	2000

Other Studies

87 other study(ies) available for chloroquine and halofantrine

Article	Year
Structure-activity relationships of novel anti-malarial agents. Part 2: cinnamic acid derivatives. Bioorganic & medicinal chemistry letters, 2001, Feb-12, Volume: 11, Issue:3 Topics: Animals; Antimalarials; Cinnamates; Combinatorial Chemistry Techniques; Inhibitory Concentration 50; Microbial Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2001
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
Orally active 1,2,4-trioxanes: synthesis and antimalarial assessment of a new series of 9-functionalized 3-(1-arylvinyl)-1,2,5-trioxaspiro[5.5]undecanes against multi-drug-resistant plasmodium yoelii nigeriensis in mice. Journal of medicinal chemistry, 2006, May-04, Volume: 49, Issue:9 Topics: Administration, Oral; Amination; Animals; Antimalarials; Artemisinins; Drug Resistance, Multiple; Heterocyclic Compounds; Malaria; Mice; Molecular Structure; Plasmodium yoelii; Structure-Activity Relationship; Survival Rate	2006
Differential effects of quinoline antimalarials on endocytosis in Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Amodiaquine; Animals; Antimalarials; Blotting, Western; Chloroquine; Endocytosis; Erythrocytes; Hemoglobins; Humans; Mefloquine; Peroxidase; Phenanthrenes; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Quinolines	2008
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century. Journal of medicinal chemistry, 2009, Mar-12, Volume: 52, Issue:5 Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Benzylamines; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Female; Haplorhini; Heme; Humans; Malaria; Mice; Models, Molecular; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Structure-Activity Relationship	2009
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7 Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Identification and optimization of an aminoalcohol-carbazole series with antimalarial properties. ACS medicinal chemistry letters, 2013, Nov-14, Volume: 4, Issue:11 Topics:	2013
Antimalarial activity of 4-amidinoquinoline and 10-amidinobenzonaphthyridine derivatives. Journal of medicinal chemistry, 2015, Apr-23, Volume: 58, Issue:8 Topics: Animals; Antimalarials; Hep G2 Cells; Humans; Malaria; Malaria, Falciparum; Male; Mice; Naphthyridines; Plasmodium berghei; Plasmodium falciparum; Quinolines	2015
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14 Topics: Amides; Animals; Antimalarials; Hep G2 Cells; Humans; Hydrazones; Malaria; Mice; Phenanthrenes; Plasmodium berghei; Stereoisomerism; Structure-Activity Relationship	2017
[Treatment of malaria in children in France]. Pediatrie, 1992, Volume: 47, Issue:5 Topics: Antimalarials; Child; Chloroquine; France; Humans; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Phenanthrenes; Quinine	1992
Plasmodium falciparum: effect of chloroquine, halofantrine and pyrimethamine on the infectivity of gametocytes for Anopheles stephensi mosquitoes. Annals of tropical medicine and parasitology, 1992, Volume: 86, Issue:2 Topics: Animals; Anopheles; Antimalarials; Chloroquine; Insect Vectors; Phenanthrenes; Plasmodium falciparum; Pyrimethamine	1992
In vitro activity of halofantrine and its relationship to other standard antimalarial drugs against African isolates and clones of Plasmodium falciparum. The American journal of tropical medicine and hygiene, 1992, Volume: 47, Issue:4 Topics: Africa; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Phenanthrenes; Plasmodium falciparum	1992
A new model for testing gametocytocidal effects of some antimalarial drugs on Plasmodium falciparum in vitro. Annals of tropical medicine and parasitology, 1992, Volume: 86, Issue:3 Topics: Animals; Anopheles; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; In Vitro Techniques; Models, Biological; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine	1992
Proposals for a new therapeutic strategy for simple Plasmodium falciparum malaria attacks in Cameroon. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1992, Volume: 43, Issue:2 Topics: Administration, Oral; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine	1992
Mefloquine-halofantrine cross-resistance in Plasmodium falciparum induced by intermittent mefloquine pressure. The American journal of tropical medicine and hygiene, 1992, Volume: 47, Issue:3 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine	1992
Susceptibility of Plasmodium falciparum strains to mefloquine in an urban area in Senegal. Bulletin of the World Health Organization, 1992, Volume: 70, Issue:3 Topics: Adolescent; Adult; Aminoquinolines; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Humans; In Vitro Techniques; Infant; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum	1992
Type RI resistance to halofantrine in West Africa. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:4 Topics: Animals; Antimalarials; Biological Availability; Chloroquine; Cote d'Ivoire; Drug Resistance; Follow-Up Studies; France; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Phenanthrenes; Plasmodium falciparum; Quinine; Recurrence; Travel	1991
Malaria vaccines in the future--what strategies now? The Southeast Asian journal of tropical medicine and public health, 1991, Volume: 22, Issue:2 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Forecasting; Humans; Malaria; Mosquito Control; Phenanthrenes; Plasmodium; Protozoan Vaccines	1991
[Malaria in the republic of São Tomé and Principe. Epidemiologic evaluation and chemoresistance of P. falciparum]. Bulletin de la Societe de pathologie exotique (1990), 1991, Volume: 84, Issue:3 Topics: Age Factors; Animals; Antimalarials; Atlantic Islands; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Seasons; Sex Factors; Splenomegaly	1991
Drug use and design in the nineties. Acta Leidensia, 1991, Volume: 60, Issue:1 Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine	1991
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand. The American journal of tropical medicine and hygiene, 1991, Volume: 44, Issue:5 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Butylated Hydroxytoluene; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Mefloquine; Molecular Structure; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Sesquiterpenes; Thailand	1991
[Imported malaria in Bordeaux in 1989. Epidemiologic, clinical and therapeutic study of 71 cases]. Bulletin de la Societe de pathologie exotique (1990), 1990, Volume: 83, Issue:5 Topics: Animals; Antimalarials; Chloroquine; Female; France; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Travel	1990
[The treatment of imported Plasmodium falciparum malaria with halofantrine. Apropos of 59 case reports (corrected and republished article orginally printed in Med Trop (Mars) 1990 Jan-Mar;50(1):113-7)]. Medecine tropicale : revue du Corps de sante colonial, 1990, Volume: 50, Issue:2 Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Drug Resistance; Female; Humans; Malaria; Male; Phenanthrenes; Plasmodium falciparum; Travel	1990
[Cross resistance to mefloquine and halofantrine in a case of P. falciparum malaria contracted in Sierra Leone]. Bulletin de la Societe de pathologie exotique (1990), 1990, Volume: 83, Issue:1 Topics: Adult; Animals; Antimalarials; Chloroquine; Cross Reactions; Drug Resistance; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum	1990
In vitro sensitivity of multiresistant Plasmodium falciparum to new candidate antimalarial drugs in western Thailand. The Southeast Asian journal of tropical medicine and public health, 1990, Volume: 21, Issue:1 Topics: Animals; Antimalarials; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Thailand	1990
[Insufficiency of treatment with halofantrine in chloroquinoresistant Plasmodium falciparum malaria in Sierra Leone]. Annales de medecine interne, 1990, Volume: 141, Issue:5 Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance; Female; Humans; Malaria; Phenanthrenes; Plasmodium falciparum; Sierra Leone	1990
Halofantrine and pruritus. Lancet (London, England), 1989, Aug-12, Volume: 2, Issue:8659 Topics: Child; Child, Preschool; Chloroquine; Drug Eruptions; Humans; Nigeria; Phenanthrenes; Pruritus; Time Factors	1989
Hypoglycaemia and antimalarial drugs: quinidine and release of insulin. British medical journal (Clinical research ed.), 1986, May-17, Volume: 292, Issue:6531 Topics: Amodiaquine; Antimalarials; Blood Glucose; Chloroquine; Humans; Hypoglycemia; Insulin; Mefloquine; Phenanthrenes; Quinidine; Quinolines; Thailand	1986
Evaluation of an in vitro assay system for drug susceptibility of field isolates of Plasmodium falciparum from southern Thailand. The American journal of tropical medicine and hygiene, 1988, Volume: 38, Issue:1 Topics: Amodiaquine; Animals; Antimalarials; Butylated Hydroxytoluene; Chloroquine; Humans; Mefloquine; Parasitology; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Quinolines; Thailand; Triazines	1988
Antimalarial drug susceptibility testing of Plasmodium falciparum in Thailand using a microdilution radioisotope method. The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:2 Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Lethal Dose 50; Malaria; Male; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Quinolines; Thailand	1985
Mefloquine failure in a case of falciparum malaria induced with a multidrug-resistant isolate in a non-immune subject. The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:4 Topics: Adult; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Pyridines; Quinine; Quinolines	1985
Plasmodium falciparum in Madagascar: in vivo and in vitro sensitivity to seven drugs. Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:4 Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Humans; Infant; Madagascar; Malaria; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines	1985
[In vivo and in vitro sensitivity to 4-aminoquinolines of Plasmodium falciparum in Madagascar: results of 2 years' study]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1985, Volume: 78, Issue:5 Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Madagascar; Malaria; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines	1985
[Drug sensitivity of Plasmodium falciparum in Madagascar. V. Study of the in vitro activity of quinine, mefloquine and halofantrine]. Archives de l'Institut Pasteur de Madagascar, 1984, Volume: 51, Issue:1 Topics: Antimalarials; Chloroquine; Humans; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Quinolines	1984
Effect of halofantrine and its desbutyl metabolite on lymphocyte proliferation dynamics. Life sciences, 1995, Volume: 57, Issue:14 Topics: Adult; Analysis of Variance; Animals; Antimalarials; Cell Division; Chloroquine; Humans; In Vitro Techniques; Lymphocytes; Male; Phenanthrenes; Rats; Rats, Sprague-Dawley	1995
Current views on the mechanisms of resistance to quinoline-containing drugs in Plasmodium falciparum. Annals of tropical medicine and parasitology, 1995, Volume: 89, Issue:2 Topics: Animals; Antimalarials; Biological Transport; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Phenanthrenes; Plasmodium falciparum; Verapamil	1995
Quinine resistant falciparum malaria acquired in east Africa. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1995, Volume: 46, Issue:1 Topics: Adult; Africa, Eastern; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetracycline	1995
Halofantrine in acute malaria. The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:5 Topics: Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Malaria, Vivax; Phenanthrenes	1994
Plasmodium falciparum and Plasmodium vivax: lactate dehydrogenase activity and its application for in vitro drug susceptibility assay. Experimental parasitology, 1995, Volume: 80, Issue:2 Topics: Animals; Antimalarials; Chloroquine; Colorimetry; Erythrocytes; Humans; L-Lactate Dehydrogenase; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax; Quinine	1995
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro. The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:5 Topics: Animals; Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Blotting, Southern; Chloroquine; DNA Primers; DNA, Protozoan; Drug Resistance; Gene Amplification; Gene Expression; Genes, Protozoan; Mefloquine; Molecular Sequence Data; Phenanthrenes; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Quinine; RNA, Messenger; Selection, Genetic; Sequence Homology, Nucleic Acid; Sesquiterpenes	1994
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives. Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:2 Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Mefloquine; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Triazines	1994
In vitro activity of pyrimethamine, cycloguanil, and other antimalarial drugs against African isolates and clones of Plasmodium falciparum. The American journal of tropical medicine and hygiene, 1994, Volume: 50, Issue:2 Topics: Africa; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Triazines	1994
[Difficulties of diagnosis and treatment of malaria outbreaks in Europeans living in Burkina Faso]. Bulletin de la Societe de pathologie exotique (1990), 1993, Volume: 86, Issue:5 Topics: Adult; Burkina Faso; Child, Preschool; Chloroquine; Drug Resistance; Europe; Humans; Infant; Malaria, Falciparum; Phenanthrenes; Recurrence	1993
Development of halofantrine resistance and determination of cross-resistance patterns in Plasmodium falciparum. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:11 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Erythrocytes; Humans; Phenanthrenes; Plasmodium falciparum	1993
In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum. The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes	1993
Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro. The American journal of tropical medicine and hygiene, 1993, Volume: 48, Issue:3 Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Erythrocytes; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Serial Passage; Vacuoles	1993
Plasmodium falciparum: role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial agents. Experimental parasitology, 1993, Volume: 76, Issue:4 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Pyridines; Quinolines; Stereoisomerism; Structure-Activity Relationship	1993
A case of dual chloroquine and halofantrine treatment failure in Zimbabwe. The Central African journal of medicine, 1995, Volume: 41, Issue:10 Topics: Adult; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Male; Phenanthrenes; Pyrimethamine; Sulfadoxine; Zimbabwe	1995
Plasmodium falciparum: molecular characterization of multidrug-resistant Cambodian isolates. Experimental parasitology, 1996, Volume: 82, Issue:2 Topics: Alleles; Animals; Antimalarials; Blotting, Southern; Cambodia; Chloroquine; Codon; DNA Fingerprinting; DNA, Protozoan; Drug Resistance, Multiple; Folic Acid Antagonists; Genes, Protozoan; Genetic Variation; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Polymorphism, Genetic; Proguanil; Pyrimethamine; Triazines	1996
[Diagnostic and prognostic importance of laboratory tests in malaria in airports. Study of six recent cases]. Pathologie-biologie, 1996, Volume: 44, Issue:4 Topics: Adult; Aerospace Medicine; Antimalarials; Chloroquine; Female; France; Humans; Malaria, Falciparum; Male; Microbiological Techniques; Middle Aged; Phenanthrenes; Platelet Count; Prognosis; Quinine	1996
In vitro selection of halofantrine resistance in Plasmodium falciparum is not associated with increased expression of Pgh1. Molecular and biochemical parasitology, 1996, Dec-02, Volume: 83, Issue:1 Topics: Animals; Antimalarials; ATP-Binding Cassette Transporters; Biological Transport; Chloroquine; DNA Fingerprinting; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Gene Dosage; Gene Expression; Immunoblotting; Mefloquine; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Selection, Genetic; Sequence Analysis, DNA; Verapamil	1996
The chemotherapy of rodent malaria. LIV. Combinations of 'Fenozan B07' (Fenozan-50F), a difluorinated 3,3'-spirocyclopentane 1,2,4-trioxane, with other drugs against drug-sensitive and drug-resistant parasites. Annals of tropical medicine and parasitology, 1997, Volume: 91, Issue:1 Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Drug Antagonism; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Malaria; Mefloquine; Mice; Naphthyridines; Parasitemia; Phenanthrenes; Phenylpropionates; Plasmodium berghei; Plasmodium yoelii	1997
Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum. Molecular and biochemical parasitology, 1997, Volume: 85, Issue:1 Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Genes, Protozoan; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Recombinant Proteins; Saccharomyces cerevisiae; Tetrahydrofolate Dehydrogenase; Triazines	1997
Plasmodium falciparum: evaluation of lactate dehydrogenase in monitoring therapeutic responses to standard antimalarial drugs in Nigeria. Experimental parasitology, 1997, Volume: 87, Issue:3 Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; L-Lactate Dehydrogenase; Malaria, Falciparum; Male; Monitoring, Physiologic; Nigeria; Phenanthrenes; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome	1997
Effect of altered serum lipid concentrations on the IC50 of halofantrine against Plasmodium falciparum. Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:2 Topics: Animals; Antimalarials; Chloroquine; Culture Media, Conditioned; Humans; Lipoproteins; Male; Phenanthrenes; Plasmodium falciparum; Protein Binding; Reference Values; Triglycerides	1998
In vitro activity of artemether against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial drugs. The American journal of tropical medicine and hygiene, 1998, Volume: 58, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Erythrocytes; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Senegal; Sesquiterpenes	1998
Follow-up of the susceptibility of Plasmodium falciparum to antimalarials in Gabon. The American journal of tropical medicine and hygiene, 1998, Volume: 58, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Follow-Up Studies; Gabon; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes; Sulfadoxine	1998
In vitro sensitivity of Plasmodium falciparum to halofantrine compared with chloroquine, quinine and mefloquine in the region of Bobo-Dioulasso, Burkina Faso (West Africa). Tropical medicine & international health : TM & IH, 1998, Volume: 3, Issue:5 Topics: Animals; Antimalarials; Burkina Faso; Chloroquine; Drug Resistance; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine	1998
Central role of hemoglobin degradation in mechanisms of action of 4-aminoquinolines, quinoline methanols, and phenanthrene methanols. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:11 Topics: Amodiaquine; Antimalarials; Chloroquine; Hemoglobins; Humans; Leucine; Mefloquine; Phenanthrenes; Primaquine; Protease Inhibitors	1998
In vitro susceptibility of Gabonese wild isolates of Plasmodium falciparum to artemether, and comparison with chloroquine, quinine, halofantrine and amodiaquine. Parasitology, 1998, Volume: 117 ( Pt 6) Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Gabon; Humans; Infant; Malaria, Falciparum; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes	1998
In vitro susceptibility of African isolates of Plasmodium falciparum from Gabon to pyronaridine. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:1 Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Gabon; Humans; Infant; Malaria, Falciparum; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Quinine	1999
[The proper use of antimalarial drugs currently available]. Bulletin de la Societe de pathologie exotique (1990), 1998, Volume: 91, Issue:5 Pt 1-2 Topics: Animals; Antimalarials; Chemoprevention; Chloroquine; Contraindications; Drug Combinations; Drug Resistance; Endemic Diseases; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Travel	1998
[Pulmonary manifestations associated with malaria]. Revue de pneumologie clinique, 1998, Volume: 54, Issue:6 Topics: Adult; Anti-Bacterial Agents; Antimalarials; Bronchitis; Child; Chloroquine; Female; Humans; Infant, Newborn; Lung Diseases; Malaria, Falciparum; Male; Mefloquine; Oxygen Inhalation Therapy; Phenanthrenes; Pleurisy; Pregnancy; Pregnancy Complications, Parasitic; Pulmonary Edema; Quinidine; Quinine; Respiratory Distress Syndrome, Newborn; Travel	1998
In vitro susceptibility of African Plasmodium falciparum isolates to dihydroartemisinin and the risk factors for resistance to qinghaosu. Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Evaluation, Preclinical; Drug Resistance; France; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes; Travel	1998
Phenotypic and genotypic characteristics of recently adapted isolates of Plasmodium falciparum from Thailand. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:3 Topics: Animals; Antimalarials; Blotting, Western; Chloroquine; DNA Fingerprinting; DNA, Protozoan; Drug Resistance; Electrophoresis, Agar Gel; Gene Dosage; Genotype; Humans; Malaria, Falciparum; Mefloquine; Penfluridol; Phenanthrenes; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Quinine; Thailand; Verapamil	1999
[Health assessments of a military company stationed on the Maroni River in French Guiana]. Medecine tropicale : revue du Corps de sante colonial, 1999, Volume: 59, Issue:1 Topics: Acclimatization; Animals; Anti-Bacterial Agents; Antimalarials; Chloroquine; Condoms; Crotalid Venoms; Crotalus; Dermatomycoses; Doxycycline; France; French Guiana; Health Education; HIV Infections; Humans; Leishmaniasis, Cutaneous; Malaria, Falciparum; Military Personnel; Phenanthrenes; Quinine; Risk Factors; Sexual Abstinence; Snake Bites; Staphylococcal Skin Infections; Tropical Medicine	1999
The microculture tetrazolium assay (MTA): another colorimetric method of testing Plasmodium falciparum chemosensitivity. Annals of tropical medicine and parasitology, 1999, Volume: 93, Issue:1 Topics: Animals; Antimalarials; Chloroquine; Colorimetry; Dose-Response Relationship, Drug; Drug Resistance; L-Lactate Dehydrogenase; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetrazolium Salts	1999
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study. Parasitology, 1999, Volume: 119 ( Pt 5) Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes	1999
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature, 2000, Feb-24, Volume: 403, Issue:6772 Topics: Amino Acid Substitution; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Mefloquine; Mutation; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes; Verapamil	2000
In vitro susceptibility of Plasmodium falciparum to four antimalarial drugs in the Central Province of Papua New Guinea. Papua and New Guinea medical journal, 1998, Volume: 41, Issue:2 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Mefloquine; Microbial Sensitivity Tests; Papua New Guinea; Phenanthrenes; Plasmodium falciparum; Quinine	1998
Effects of anti-protozoal drugs and histopathological studies on trypanosome species. FEMS immunology and medical microbiology, 2001, Volume: 30, Issue:1 Topics: Animals; Chloroquine; Female; Humans; Male; Metronidazole; Parasitic Sensitivity Tests; Phenanthrenes; Pyrimethamine; Rats; Trypanosoma; Trypanosomiasis	2001
Halofantrine in G-6 PD deficiency. The Journal of the Association of Physicians of India, 1997, Volume: 45, Issue:11 Topics: Aged; Antimalarials; Chloroquine; Glycogen Storage Disease Type I; Hemolysis; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Phenanthrenes	1997
[A collective malarial infestation during a humanitarian mission in west Africa]. Bulletin de la Societe de pathologie exotique (1990), 2002, Volume: 95, Issue:2 Topics: Adult; Altruism; Animals; Antimalarials; Body Weight; Chemoprevention; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Male; Mali; Mauritania; Middle Aged; Morocco; Phenanthrenes; Plasmodium falciparum; Proguanil; Quinine; Travel	2002
In vitro activity of chloroquine, quinine, mefloquine and halofantrine against Gabonese isolates of Plasmodium falciparum. Tropical medicine & international health : TM & IH, 2003, Volume: 8, Issue:1 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Gabon; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine	2003
[Adverse drug reactions (ADRs) to antimalarial drugs. Analysis of spontaneous report from the French pharmacovigilance database (1996-2000)]. Presse medicale (Paris, France : 1983), 2003, Jan-25, Volume: 32, Issue:3 Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Antimalarials; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Chloroquine; Female; France; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenanthrenes; Proguanil; Psychoses, Substance-Induced; Sex Factors	2003
In-vitro sensitivity of Plasmodium falciparum to chloroquine, halofantrine, mefloquine and quinine in Madagascar. East African medical journal, 2002, Volume: 79, Issue:5 Topics: Animals; Antimalarials; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Hospitals, Public; Hospitals, Urban; Humans; Madagascar; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Rural Health	2002
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum. Biochemistry, 2004, May-04, Volume: 43, Issue:17 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfanilamide; Sulfanilamides; Ultraviolet Rays	2004
Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents. Molecular cell, 2004, Sep-24, Volume: 15, Issue:6 Topics: Alanine; Alleles; Amantadine; Amino Acid Sequence; Amino Acid Substitution; Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Genes, Protozoan; Haplotypes; Hemin; Membrane Proteins; Membrane Transport Proteins; Microsatellite Repeats; Molecular Sequence Data; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Point Mutation; Protein Structure, Secondary; Protozoan Proteins; Recombination, Genetic; Verapamil	2004
Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC50 values using a Bayesian approach. Malaria journal, 2007, Jan-17, Volume: 6 Topics: Algorithms; Animals; Antimalarials; Artemisinins; Artesunate; Bayes Theorem; Chloroquine; Computer Simulation; Dose-Response Relationship, Drug; Drug Resistance; False Positive Reactions; Inhibitory Concentration 50; Mefloquine; Models, Biological; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes	2007
The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs. Annals of tropical medicine and parasitology, 2007, Volume: 101, Issue:5 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Infant; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes	2007
Chemotherapeutic interaction between Khaya grandifoliola (WELW) CDC stem bark extract and two anti-malarial drugs in mice. African journal of traditional, complementary, and alternative medicines : AJTCAM, 2010, Volume: 7, Issue:4 Topics: Administration, Oral; Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; Malaria; Meliaceae; Mice; Nigeria; Phenanthrenes; Plant Bark; Plant Extracts; Plasmodium yoelii; Treatment Outcome	2010
Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:3 Topics: Aminoquinolines; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Evolution, Molecular; Fluorenes; French Guiana; Gene Dosage; Haplotypes; Humans; Inhibitory Concentration 50; Longitudinal Studies; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Practice Guidelines as Topic; Protozoan Proteins; Quinine	2012
Distribution of drug resistance genotypes in Plasmodium falciparum in an area of limited parasite diversity in Saudi Arabia. The American journal of tropical medicine and hygiene, 2012, Volume: 86, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Phenanthrenes; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Saudi Arabia; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Young Adult	2012
Treatment of murine cerebral malaria by artemisone in combination with conventional antimalarial drugs: antiplasmodial effects and immune responses. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Animals; Antimalarials; Artemisinins; Cell Line; Cell Survival; Cells, Cultured; Chloroquine; Doxycycline; Drug Synergism; Drug Therapy, Combination; Erythrocytes; Humans; Interleukin-10; Interleukin-4; Malaria, Cerebral; Mefloquine; Mice; Mice, Inbred C57BL; Monocytes; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium berghei; Plasmodium falciparum	2014