Compounds > chloroquine

chloroquine and ferroquine

chloroquine has been researched along with ferroquine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (47.06)29.6817
2010's8 (47.06)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Atteke, C; Aubouy, A; Brocard, J; Deloron, P; Lébibi, J; Maciejewski, L; Ndong, JM1
Chim, P; Fandeur, T; Lim, P; Maciejewski, L; Nhem, S; Sem, R1
Brocard, J; Dive, D; Fraisse, L; Khalife, J; Lafitte, S; Pierrot, C1
Biot, C; Brocard, J; Daher, W; Dive, D; Fandeur, T; Fraisse, L; Jouin, H; Khalife, J; Pelinski, L; Pradines, B; Viscogliosi, E1
Biot, C; Brocard, J; Chavain, N; Daher, W; Dive, D; Forfar-Bares, I; Fraisse, L; Jarry, C; Khalife, J; Melnyk, P; Ndiaye, CM; Pelinski, L; Pellet, A; Pradines, B1
Dietz, K; Kreidenweiss, A; Kremsner, PG; Mordmüller, B1
Biot, C; Dive, D1
Amalvict, R; Baret, E; Briolant, S; Fontaine, A; Fraisse, L; Fusaï, T; Henry, M; Mosnier, J; Pradines, B; Rogier, C1
Anstey, NM; Chalfein, F; Kenangalem, E; Machunter, B; Marfurt, J; Piera, KA; Prayoga, P; Price, RN; Tjitra, E; Wabiser, F1
Biot, C; Dive, D; Fraisse, L; Khalife, J; Nosten, F; Ter-Minassian, D1
Akala, HM; Eyase, FL; Johnson, JD; Walsh, DS1
Adam, MJ; Cawthray, JF; Chen, J; de Kock, C; Herrmann, C; Kenkel, A; Nimphius, C; Orvig, C; Patrick, BO; Salas, PF; Smith, PJ1
Fujita, H; Fukuhara, H; Furihata, M; Inoue, K; Kurabayashi, A; Sasaki, J; Shuin, T; Utsumi, K1
Blackie, MA; de Kock, C; de Villiers, KA; Jacobs, L; Smith, PJ; Smith, VJ; van Otterlo, WA1
Biot, C; Delcourt, P; Dewailly, E; Dubois, C; Gordienko, D; Kondratska, K; Kondratskyi, A; Lemière, S; Prevarskaya, N; Skryma, R; Slomianny, C; Toillon, RA; Vanden Abeele, F1
Aderibigbe, BA; Peter, S1
Chellan, P; Sadler, PJ1

Reviews

4 review(s) available for chloroquine and ferroquine

ArticleYear
Ferrocene conjugates of chloroquine and other antimalarials: the development of ferroquine, a new antimalarial.
    ChemMedChem, 2008, Volume: 3, Issue:3

    Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Clinical Trials, Phase I as Topic; Drug Resistance; Ferrous Compounds; Metallocenes; Organometallic Compounds; Plasmodium falciparum

2008
The antimalarial ferroquine: from bench to clinic.
    Parasite (Paris, France), 2011, Volume: 18, Issue:3

    Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Clinical Trials, Phase II as Topic; Drug Resistance; Ferrous Compounds; Humans; Malaria, Falciparum; Malaria, Vivax; Metallocenes; Plasmodium falciparum; Plasmodium vivax

2011
Ferrocene-Based Compounds with Antimalaria/Anticancer Activity.
    Molecules (Basel, Switzerland), 2019, Oct-07, Volume: 24, Issue:19

    Topics: Aminoquinolines; Antimalarials; Antineoplastic Agents; Chloroquine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Ferrous Compounds; Humans; Malaria; Metallocenes; Neoplasms; Plasmodium falciparum

2019
Enhancing the Activity of Drugs by Conjugation to Organometallic Fragments.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Jul-17, Volume: 26, Issue:40

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Coordination Complexes; Ferrous Compounds; Humans; Malaria; Metallocenes; Molecular Structure; Organometallic Compounds; Ruthenium Compounds

2020

Other Studies

13 other study(ies) available for chloroquine and ferroquine

ArticleYear
In vitro susceptibility to a new antimalarial organometallic analogue, ferroquine, of Plasmodium falciparum isolates from the Haut-Ogooué region of Gabon.
    The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:4

    Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Drug Resistance; Ferrous Compounds; Gabon; Humans; Malaria, Falciparum; Metallocenes; Plasmodium falciparum; Quinolines

2003
The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum.
    Annals of tropical medicine and parasitology, 2004, Volume: 98, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Sesquiterpenes

2004
Analysis of immune response patterns in naïve and Plasmodium berghei-infected young rats following a ferroquine treatment.
    International journal for parasitology, 2005, Volume: 35, Issue:14

    Topics: Aminoquinolines; Animals; Antibodies, Protozoan; Antimalarials; Cell Proliferation; Cells, Cultured; Chloroquine; Enzyme-Linked Immunosorbent Assay; Ferrous Compounds; Flow Cytometry; Immunoglobulin G; Interferon-gamma; Interleukin-10; Malaria; Metallocenes; Plasmodium berghei; Rats; Rats, Inbred F344; Spleen

2005
Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure.
    Malaria journal, 2006, Feb-07, Volume: 5

    Topics: Amino Acid Sequence; Aminoquinolines; Animals; Antimalarials; Blood Cells; Cells, Cultured; Chloroquine; Drug Resistance; Ferrous Compounds; Flow Cytometry; Genetic Variation; Inhibitory Concentration 50; Membrane Transport Proteins; Metallocenes; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins

2006
Probing the role of the covalent linkage of ferrocene into a chloroquine template.
    Journal of medicinal chemistry, 2006, Jul-27, Volume: 49, Issue:15

    Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Ferrous Compounds; Hemeproteins; Metallocenes; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship

2006
In vitro activity of ferroquine (SAR97193) is independent of chloroquine resistance in Plasmodium falciparum.
    The American journal of tropical medicine and hygiene, 2006, Volume: 75, Issue:6

    Topics: Aminoquinolines; Animals; Antimalarials; Blood; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Ferrous Compounds; Humans; Malaria, Falciparum; Metallocenes; Parasitemia; Plasmodium falciparum

2006
In vitro activity of ferroquine is independent of polymorphisms in transport protein genes implicated in quinoline resistance in Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Aminoquinolines; Amodiaquine; Animals; Chloroquine; Drug Resistance, Bacterial; Ferrous Compounds; Mefloquine; Membrane Transport Proteins; Metallocenes; Microsatellite Repeats; Molecular Structure; Plasmodium falciparum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines

2008
Ex vivo drug susceptibility of ferroquine against chloroquine-resistant isolates of Plasmodium falciparum and P. vivax.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:9

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Drug Resistance; Ferrous Compounds; Metallocenes; Plasmodium falciparum

2011
Inhibitory activity of ferroquine, versus chloroquine, against western Kenya Plasmodium falciparum field isolates determined by a SYBR Green I in vitro assay.
    The American journal of tropical medicine and hygiene, 2011, Volume: 85, Issue:6

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Drug Resistance; Ferrous Compounds; Humans; Kenya; Malaria, Falciparum; Membrane Transport Proteins; Metallocenes; Microbial Sensitivity Tests; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins

2011
Structural characteristics of chloroquine-bridged ferrocenophane analogues of ferroquine may obviate malaria drug-resistance mechanisms.
    Journal of medicinal chemistry, 2013, Feb-28, Volume: 56, Issue:4

    Topics: Aminoquinolines; Antimalarials; Antineoplastic Agents; Cell Line, Tumor; Chloroquine; Crystallography, X-Ray; Drug Resistance; Drug Screening Assays, Antitumor; Ferrous Compounds; Hemin; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Metallocenes; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2013
The inhibition of ferrochelatase enhances 5-aminolevulinic acid-based photodynamic action for prostate cancer.
    Photodiagnosis and photodynamic therapy, 2013, Volume: 10, Issue:4

    Topics: Aminolevulinic Acid; Animals; Apoptosis; Cell Line, Tumor; Chloroquine; Deferoxamine; Drug Synergism; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Photochemotherapy; Photosensitizing Agents; Prostatic Neoplasms; Protoporphyrins

2013
Design, Synthesis, and Evaluation of Novel Ferroquine and Phenylequine Analogues as Potential Antiplasmodial Agents.
    ChemMedChem, 2015, Volume: 10, Issue:12

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Crystallography, X-Ray; Drug Design; Drug Resistance; Ferrous Compounds; Hemeproteins; Inhibitory Concentration 50; Metallocenes; Microbial Sensitivity Tests; Molecular Conformation; Octoxynol; Plasmodium falciparum; Polyethylene Glycols; Protein Binding; Structure-Activity Relationship

2015
Ferroquine, the next generation antimalarial drug, has antitumor activity.
    Scientific reports, 2017, Nov-21, Volume: 7, Issue:1

    Topics: Aminoquinolines; Animals; Antimalarials; Antineoplastic Agents; Autophagy; Caspases; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Proliferation; Chloroquine; Female; Ferrous Compounds; Hydrogen-Ion Concentration; Intracellular Membranes; Lysosomes; Metallocenes; Mice, Nude; Neoplasms; Permeability; Stress, Physiological; Xenograft Model Antitumor Assays

2017