Compounds > chloroquine

chloroquine and everolimus

chloroquine has been researched along with everolimus in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's8 (72.73)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bader, S; Forooghian, F; Gilman, A; HayGlass, KT; Hsiao, CC; Rempel, J; Schultz, KR; Su, WN1
Beckmann, MW; Brandt, I; Dittmer, A; Dittmer, J; Dittrich, R; Fabry, B; Fasching, PA; Groh, N; Hoffmann, I; Kalender, WA; Koch, T; Koppitz, F; Loehberg, CR; Lotz, L; Lux, MP; Mueller, A; Oeser, S; Polier, A; Schrauder, MG; Strick, R; Strissel, PL; Wachter, DL1
Balestrieri, ML; Caraglia, M; D'Onofrio, N; Di Domenico, G; Grimaldi, A; Lamberti, M; Nocera, C; Pantano, F; Santini, D; Tonini, G; Zoccoli, A1
Chang, J; Cheng, L; Ji, D; Li, J; Liu, R; Liu, X; Sun, Z; Wang, C; Wang, S; Wang, X; Zhang, X; Zhang, Z; Zheng, B; Zheng, R1
Boccellino, M; Caraglia, M; Desiderio, V; Di Lorenzo, G; Grimaldi, A; Lombardi, A; Misso, G; Pantano, F; Santini, D; Vitiello, PP; Zappavigna, S; Zoccoli, A1
Avniel-Polak, S; Glaser, B; Gross, DJ; Grozinsky-Glasberg, S; Leibowitz, G; Riahi, Y1
Avniel-Polak, S; Doviner, V; Gross, DJ; Grozinsky-Glasberg, S; Leibowitz, G1
Bai, Y; Hou, G; Jia, A; Lu, J; Lu, Z; Ren, Y; Wang, P; Wang, Y; Zhang, J1
Alwayn, IPJ; de Fijter, JW; de Vries, APJ; Janson, JA; Meziyerh, S; Moes, DJAR; Reinders, MEJ; van Etten, RW; van Gelder, T; Zwart, TC1

Reviews

1 review(s) available for chloroquine and everolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for chloroquine and everolimus

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Evaluation for synergistic suppression of T cell responses to minor histocompatibility antigens by chloroquine in combination with tacrolimus and a rapamycin derivative, SDZ-RAD.
    Bone marrow transplantation, 2002, Volume: 30, Issue:12

    Topics: Animals; Antigen Presentation; Apoptosis; Cells, Cultured; Chloroquine; Cytokines; Drug Evaluation, Preclinical; Drug Synergism; Everolimus; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Minor Histocompatibility Antigens; Recombinant Proteins; Sirolimus; T-Lymphocytes; Tacrolimus

2002
Akt and p53 are potential mediators of reduced mammary tumor growth by cloroquine and the mTOR inhibitor RAD001.
    Biochemical pharmacology, 2012, Feb-15, Volume: 83, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chloroquine; Everolimus; Female; G1 Phase Cell Cycle Checkpoints; Humans; Immunosuppressive Agents; Mice; Mice, Nude; Neoplasms, Experimental; Oncogene Protein v-akt; Sirolimus; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53

2012
The synergistic effect of everolimus and chloroquine on endothelial cell number reduction is paralleled by increased apoptosis and reduced autophagy occurrence.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Count; Cell Proliferation; Cell Survival; Chloroquine; Drug Synergism; Endothelial Cells; Everolimus; Humans; Membrane Proteins; Models, Biological; Proto-Oncogene Proteins c-bcl-2; Sirolimus; Stem Cells

2013
The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Adenine; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Butadienes; Cell Line, Tumor; Chloroquine; Cyclin D1; Drug Synergism; Everolimus; Flavonoids; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 3-Ring; Humans; Membrane Proteins; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Nitriles; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2014
Antagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells.
    Cancer biology & therapy, 2015, Volume: 16, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Chloroquine; Drug Synergism; Everolimus; Humans; Kidney Neoplasms; Lysosomes; Membrane Proteins; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; TOR Serine-Threonine Kinases

2015
Abrogation of Autophagy by Chloroquine Alone or in Combination with mTOR Inhibitors Induces Apoptosis in Neuroendocrine Tumor Cells.
    Neuroendocrinology, 2016, Volume: 103, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Everolimus; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Ki-67 Antigen; Microtubule-Associated Proteins; Neuroendocrine Tumors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Time Factors; TOR Serine-Threonine Kinases

2016
Combining chloroquine with RAD001 inhibits tumor growth in a NEN mouse model.
    Endocrine-related cancer, 2018, Volume: 25, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Chloroquine; Everolimus; Humans; Immunosuppressive Agents; Mechanistic Target of Rapamycin Complex 1; Mice, Nude; Neuroendocrine Tumors; Xenograft Model Antitumor Assays

2018
Inhibition of autophagy improves resistance and enhances sensitivity of gastric cancer cells to cisplatin.
    Canadian journal of physiology and pharmacology, 2020, Volume: 98, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Beclin-1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Cisplatin; Drug Resistance, Neoplasm; Everolimus; Gene Knockdown Techniques; Humans; RNA, Small Interfering; Stomach Neoplasms

2020
Severe COVID-19 in a renal transplant recipient: A focus on pharmacokinetics.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020, Volume: 20, Issue:7

    Topics: Adult; Antiviral Agents; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; Drug Combinations; Drug Interactions; Everolimus; Humans; Immunocompromised Host; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Lopinavir; Male; Netherlands; Pandemics; Pneumonia, Viral; Radiography, Thoracic; Ritonavir; SARS-CoV-2; Transplant Recipients; Treatment Outcome

2020