chloroquine and emetine

chloroquine has been researched along with emetine in 196 studies

Research

Studies (196)

TimeframeStudies, this research(%)All Research%
pre-1990137 (69.90)18.7374
1990's4 (2.04)18.2507
2000's9 (4.59)29.6817
2010's38 (19.39)24.3611
2020's8 (4.08)2.80

Authors

AuthorsStudies
Angenot, L; Brandt, V; De Pauw, M; DeMol, P; Frédérich, M; Hayette, M; Penelle, J; Prosperi, C; Tits, M1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Bedir, E; Dunbar, DC; Ferreira, D; Khan, SI; Muhammad, I; Takamatsu, S; Tekwani, BL; Walker, LA1
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chibale, K; D'hooghe, M; De Kimpe, N; Dekeukeleire, S; Lategan, C; Mollet, K; Smith, PJ1
Arfan, M; Hu, LH; Lategan, CA; Rafique, J; Smith, PJ; Xiao, ZY; Zhang, GP1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Breytenbach, JC; Lategan, CA; Lombard, MC; N'Da, DD; Smith, PJ2
Chen, X; Lin, X; Skolnik, S; Wang, J1
Chibale, K; D'hooghe, M; De Kimpe, N; Kenis, S; Lategan, C; Smith, PJ; Vervisch, K1
Chibale, K; Egan, TJ; Hunter, R; Joshi, MC; Martin, RE; Smith, PJ; Summers, RL; Zishiri, VK1
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y1
Breytenbach, JC; Cloete, TT; Kock, Cd; N'da, DD; Smith, PJ; Wilma Breytenbach, J1
Breytenbach, JC; Breytenbach, JW; Cloete, TT; de Kock, C; N'Da, DD; Smith, PJ; van Heerden, L1
Breytenbach, WJ; de Kock, C; N'Da, DD; Pretorius, SI; Smith, PJ1
Chibale, K; D'hooghe, M; De Kimpe, N; Lategan, C; Müller, C; Smith, PJ; Vandekerckhove, S; Vogt, D1
Chibale, K; D'hooghe, M; De Kimpe, N; Desmet, T; Lategan, C; Smith, PJ; Törnroos, KW; Verhaeghe, T; Vervisch, K1
Barteau, S; Chibale, K; Gut, J; Heudi, O; Kameni-Tcheudji, J; Mugumbate, GC; Njoroge, M; Rosenthal, PJ; Streckfuss, J; Tukulula, M1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Egan, TJ; Hunter, R; Joshi, MC; Smith, PJ; Taylor, D; Wicht, KJ1
Chibale, K; D'hooghe, M; de Kock, C; Desmet, T; Smith, PJ; Tran, HG; Vandekerckhove, S1
Abay, ET; Barteau, S; Chibale, K; Gibhard, L; Gut, J; Kameni-Tcheudji, J; Mugumbate, GC; Njoroge, M; Norman, J; Rosenthal, PJ; Streckfuss, J; Swart, KJ; Taylor, D; Tukulula, M; Wiesner, L1
Fortuin, EE; Joubert, J; Malan, SF; Smith, PJ; Taylor, D1
Birkholtz, LM; N'Da, DD; Smit, FJ; van Biljon, RA1
Chibale, K; D'hooghe, M; Danneels, B; de Kock, C; Desmet, T; Smith, PJ; Van Herreweghe, S; Vandekerckhove, S; Willems, J1
Abay, ET; Bonnet, SL; de Kock, C; Kendrekar, P; Noreljaleel, AE; Swart, KJ; van der Westhuizen, JH; Wiesner, L; Wilhelm, A1
Chibale, K; Egan, TJ; Jurva, U; Masimirembwa, CM; Njoroge, M; Ongarora, DS; Strydom, N; Wicht, K; Wiesner, L; Wittlin, S1
Joubert, J; Kapp, E; Malan, SF; Smith, PJ; Taylor, D1
Hoppe, HC; Isaacs, M; Khanye, SD; Svogie, AL; Veale, CG1
Beteck, RM; Birkholtz, LM; Coertzen, D; Haynes, RK; N'Da, DD; Smit, FJ1
Combrinck, J; de Kock, C; N'Da, DD; Smit, FJ; Smith, PJ; Zuma, NH1
Chibale, K; De Kock, C; Espinoza-Moraga, M; Kaur, G; Njoroge, M; Okombo, J; Singh, K; Smith, PJ; Wittlin, S1
Chibale, K; Egan, TJ; Hunter, R; Joshi, MC; Ndove, J; Nsumiwa, S; Okombo, J; Taylor, D; Wiesner, L1
Chibale, K; Chopra, R; Singh, K1
Joubert, J; Kapp, E; Malan, SF; Taylor, D; Yvette, OM1
Chibale, K; Kaur, G; Pavadai, E; Wittlin, S1
Combrinck, JM; de Villiers, KA; Egan, TJ; Hunter, R; L'abbate, FP; Müller, R; Openshaw, R1
Cheuka, PM; Chibale, K; Lawrence, N; Taylor, D; Wittlin, S1
Attram, HD; Chibale, K; Wittlin, S1
Baartzes, N; Chibale, K; Seldon, R; Smith, GS; Stringer, T; Taylor, D; Warner, DF; Wittlin, S1
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT1
Hoppe, HC; Isaacs, M; Kaye, PT; Krause, RWM; Manyeruke, MH; Seldon, R; Tshiwawa, T; Warner, DF1
Boone, M; Chibale, K; Combrinck, J; D'hooghe, M; Mangelinckx, S; Smith, PJ; Van de Walle, T; Van Puyvelde, J1
Chen, J; Chen, W; Choudhry, N; Xu, D; Yang, Z; Zanin, M; Zhao, X1
Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL1
Beteck, RM; Bokosi, FRB; Hoppe, HC; Khanye, SD; Laming, D; Mbaba, M; Mtshare, TE1
Stickl, H; Werner, GT1
Ali, M1
Kuhn, E; Mono, G1
Neal, RA2
John, L; Koshy, TS; Seshadri, MS; Varkey, K1
Alzate, LF; Arriola, JA; Bengoechea, MG; Cosme, A; Diago, A; Galvany, A; Marcos, JM1
Fitzgerald, JF; Grosfeld, JL; Jessee, WF; Ryan, JM1
Degrémont, A1
Fernex, M1
Shookhoff, HB1
Kean, BH1
Lischke, JH; Smale, LE; Wagner, VP1
Jayawickrema, US; Lionel, ND1
Ahmad, I; Haider, Z; Rasul, A1
Hargrove, MD; Jenkinson, SG1
Gregory, PB1
Burke, A; Courval, JM; Samuelson, JC1
Gapud, CP; Keil, W; Reiss, CS1
Doymaz, M; Kolaitis, G; Rouse, BT1
Antoni, F; Bánfalvi, G; Csuka, I; Nghiem, LN; Oláh, I1
Aroumir, C; Cienfuegos, E; Cortinas de Nava, C; Espinosa-Aguirre, JJ; Meza, MT1
Antoni, F; Csuka, I; Hrabák, A1
Moccetti, T1
Ashton, WL; Boardman, PL; D'Sa, CJ; Everall, PH; Houghton, AW1
Jarumilinta, R; Kradolfer, F; Sackmann, W1
Fahmy, AE; Mishad, MM; Warraki, SE; Youssef, HH1
Dawson, RG; Nielsen, AA; Stanford, W1
Johnson, RL; Rogers, JW; Zinneman, HH1
Wolfensberger, HR1
Knauer, CM1
De Carneri, I1
Chearanai, O; Kalayasiri, C; Na-Songkla, S; Pleechnida, R; Plengvanit, U; Suwanik, R; Viranuvatti, V1
Bohrer, SP1
Cervantes, LF1
Judy, KL1
Pittman, FE; Pittman, JC1
Powell, SJ1
Azevedo Vinhaes, L; Costa Guimarães, A; Neves Abreu, W; Pericles Esteves, J; Santos Filho, A1
Mohr, W2
Joseph, WL; Mulder, DG; Price, JE1
Alvarez, V; Grube, D; Stillman, AE1
Duma, RJ; Markowitz, SM; Martinez, AJ; Shiel, FO1
Kumar, BR; Lal, M; Nanda, RB; Singh, I1
Hoskins, DW; Knight, R; Marsden, PD; Schultz, MG1
Longerbeam, JK; Reeves, CD; Tetz, EM1
Ansari, ZA; Gopal, MS; Rai, AN; Skaria, J; Vaish, SK1
Chhuttani, PN; Datta, DV; Singh, SA1
Tsai, SH1
Malik, TK; Nadkarni, SV; Parashar, SK; Varmi, RA1
Davies, ER; Gough, KR; Hinchliffe, A; Matthews, AW; Ross, FG1
Perumal, JR; Ramachandran, S; Sivalingam, S1
Griffin, FM1
Wilde, H1
Collin, DB; Henn, RM1
Saif, M1
Mialaret, J1
Mohankumar, VK; Padmanabhan, V; Poulose, KP; Ramachandran, M; Sahajanandan, VK1
Bindschadler, DD1
Huggins, D1
Spellberg, MA1
Ali Ata, AH; el-Raziky, ES1
Benchetrit, J; Paraf, A; Rousset, JJ; Trad, J1
Johnston, GS; Jones, AE1
Calvillo-Juárez, M; Green, L; Ibarra-Pérez, C; Vargas de la Cruz, J1
Gorbach, SL; Heller, RF; Loeb, HS; Rahimtoda, SH; Tatooles, CJ1
Gutiérrez, G; Sánchez-Rebolledo, JM; Serafín, F1
Tischendorf, P1
Bridgers, WF; Cunningham, RD; Gressett, G1
Elsdon-Dew, R; Powell, SJ; Wilmot, AJ1
Forjaz, A; Imhof, PR; Jarumilinta, R; Lambert, CR; Ruas, A1
MacLeod, IN; Powell, SJ; Wilmot, AJ1
Duma, RJ; Ferrell, HW; Jones, MM; Nelson, EC1
Boube, G; Boucheron, M; Kermarec, J; Lobry, M; Pernod, J; Sackpraseuth, S1
Powell, SJ; Scragg, JN3
Davies, AH; Hardman, EW; Jones, RL1
Charmot, G1
Cervantes, LF; González-Montesinos, F; Landa, L; Sepúlveda, B1
Sodeman, WA1
Seaton, DR1
Wilson, ES1
Babaev, OG1
Askerkhanov, RP1
Joseph, K; Massarrat, S; Mitzkat, HJ; Streicher, HJ1
Klein, E1
Coberly, JC; Wenger, J1
Elsdon-Dew, R; Macleod, IN; Powell, SJ; Wilmot, AJ2
Herrera-Llerandi, R1
Balwani, JH; Joglekar, GV; Kale, AK1
Burchett, PM1
Nigam, PD; Prakash, A; Sethi, RS1
Dorrough, RL1
Knight, R1
Carneiro Chaves, FJ; Cruz, I1
Wolfe, MS1
Seidel, J1
Campo, JM; Labarga, P; Milazzo, A; Pascual, J; Salcedo, J; Yanguela, J1
Kumar, VS; Mohan Rao, VK; Saxena, KC; Saxena, PN; Tripathi, LM1
Cosma, GN; Wenzel, DG1
Biagi, F1
Bianchini, C; Cifarelli, F; Paparo, BS; Sanguigni, S1
Berstein, GS; Trifunac, NP1
Bru, C; Corachán, M; García-Forcada, A; Gascón, J; Sans, M; Valls, ME1
Fayadat, L; Franc, JL; Lanet, J; Siffroi-Fernandez, S1
GAMBARDELLA, A1
DOLKART, RE1
BHATTACHARYA, RC1
SCHAIBLE, G1
ADAMS, EB; POWELL, SJ; WILMOT, AJ2
GUCCIARDI, G; TERRANOVA, S1
ASTUTO, R; SCAFFIDI, V2
ABD-EL-GHAFFAR, V1
BOIVIN, P; FAUVERT, R; PIGUET, H1
FOX, H1
CHUANG, CY; SUNG, JL; YU, JY1
SIERPINSKI, M1
BRANDT, EN; DELASHAW, JB; MANNERBERG, FD1
NWOKOLO, C1
COVO, Y; DEVRIES, A; GALDETTI, M; PINHAS, Y1
OSBORN, JR1
WINNICKI, S; WOJDAT, W1
WALTERS, J1
CHESLER, E; OPESKIN, I1
TELLA, A1
ACOSTA, AL; CARRILLO, PE1
CHANG, KC; CHIEN, TS; MENG, HY1
CHANG, TF; CHENG, S; CHIN, CM; FAN, KC; JOHN, L; SUN, KJ; TSENG, FJ; TU, CC; TU, SF; WANG, CN1
DEMICHELE, D; FINELLI, L; GAMBARDELLA, A1
MATHUR, BB; SANGHVI, LM1
JARUMILINTA, R; KRADOLFER, F1
HARINASUTA, C1
REINERTSON, JW; THOMPSON, PE1
ROOVERS, JJ; VAN STEENIS, PB1
GOLDMAN, MJ1
Deakin, J; Idris-Usman, M; Matthews, H; Nirmalan, NJ; Rajab, M1
Anastasiou, IA; Eleftheriadou, I; Tentolouris, A; Tentolouris, N; Tsilingiris, D1
Lebedev, T; Prassolov, V; Shyrokova, E; Spirin, P; Vedernikova, V1

Reviews

9 review(s) available for chloroquine and emetine

ArticleYear
Drugs for the Treatment of Zika Virus Infection.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection

2020
Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
    Journal of medicinal chemistry, 2020, 11-25, Volume: 63, Issue:22

    Topics: Antiviral Agents; China; Coronavirus Protease Inhibitors; COVID-19; COVID-19 Drug Treatment; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; SARS-CoV-2; Small Molecule Libraries

2020
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
    Medicinal research reviews, 2021, Volume: 41, Issue:1

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization

2021
[Cardiotoxic effects of drugs and various other substances. A review].
    Fortschritte der Medizin, 1978, Apr-13, Volume: 96, Issue:14

    Topics: Adrenergic Agonists; Amphetamine; Antimony; Arrhythmias, Cardiac; Arsenic Poisoning; Catecholamines; Chloroquine; Clofibrate; Cyclophosphamide; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Emetine; Endomyocardial Fibrosis; Heart; Heart Arrest; Heart Block; Humans; Hypertension; Lithium; Methysergide; Myocarditis; Myofibrils; Psychotropic Drugs

1978
Intestinal parasites.
    Gut, 1973, Volume: 14, Issue:2

    Topics: Animals; Anthelmintics; Antimony; Chloroquine; Coccidiosis; Diphyllobothriasis; Dysentery, Amebic; Emetine; Giardiasis; Humans; Infant; Intestinal Diseases, Parasitic; Liver Abscess, Amebic; Male; Metronidazole; Nematode Infections; Niclosamide; Niridazole; Schistosomiasis; Thiabendazole

1973
[Management of parasitic intestinal diseases].
    Revista brasileira de medicina, 1968, Volume: 25, Issue:10

    Topics: Amebicides; Anthelmintics; Balantidiasis; Brazil; Chloroquine; Chloroquinolinols; Dysentery, Amebic; Emetine; Furazolidone; Giardiasis; Humans; Intestinal Diseases, Parasitic; Metronidazole; Oxytetracycline; Paromomycin; Quinolines

1968
The treatment of intestinal protozoan infections.
    The Medical clinics of North America, 1982, Volume: 66, Issue:3

    Topics: Amebicides; Antimalarials; Antiprotozoal Agents; Balantidiasis; Chloroquine; Coccidiosis; Dientamoebiasis; Drug Combinations; Dysentery, Amebic; Emetine; Furans; Furazolidone; Giardiasis; Humans; Intestinal Diseases, Parasitic; Iodoquinol; Liver Abscess, Amebic; Metronidazole; Paromomycin; Quinacrine; Sulfamethoxazole; Tetracycline; Tinidazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1982
[Fasciola hepatica. Review and current status of the disease].
    Revista clinica espanola, 1984, May-31, Volume: 173, Issue:4

    Topics: Animals; Chloroquine; Cholestasis, Intrahepatic; Emetine; Fasciola hepatica; Fascioliasis; Humans; Intradermal Tests; Laparoscopy; Liver Diseases; Parasite Egg Count; Rupture, Spontaneous; Snails

1984
[Modern concepts concerning therapy of amebiasis].
    La Clinica terapeutica, 1981, Aug-31, Volume: 98, Issue:4

    Topics: Acetanilides; Amebiasis; Amebicides; Anti-Bacterial Agents; Chloroquine; Dysentery, Amebic; Emetine; Furans; Humans; Iodoquinol; Liver Abscess, Amebic; Metronidazole

1981

Trials

3 trial(s) available for chloroquine and emetine

ArticleYear
Comparison of metronidazole with emetine & chloroquine in the treatment of hepatic amoebiasis--A controlled double blind study.
    The Ceylon medical journal, 1975, Volume: 20, Issue:2

    Topics: Adult; Aged; Chloroquine; Drug Combinations; Emetine; Female; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged

1975
Treatment of amebic liver abscess with emetine hydrochloride, niridazole, and metronidazole. A controlled clinical trial.
    The American journal of tropical medicine and hygiene, 1974, Volume: 23, Issue:4

    Topics: Adult; Chloroquine; Clinical Trials as Topic; Drug Therapy, Combination; Emetine; Hallucinations; Humans; Liver Abscess, Amebic; Metronidazole; Middle Aged; Movement Disorders; Niridazole

1974
A comparative trial of dehydroemetine and emetine hydrochloride in identical dosage in amoebic liver abscess.
    Annals of tropical medicine and parasitology, 1967, Volume: 61, Issue:1

    Topics: Adult; Amebicides; Brain Abscess; Chloroquine; Drug Synergism; Electrocardiography; Emetine; Heart; Humans; Injections, Intramuscular; Liver Abscess, Amebic; Male; South Africa

1967

Other Studies

184 other study(ies) available for chloroquine and emetine

ArticleYear
Strychnogucines A and B, two new antiplasmodial bisindole alkaloids from Strychnos icaja.
    Journal of natural products, 2001, Volume: 64, Issue:1

    Topics: Alkaloids; Animals; Antimalarials; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plasmodium falciparum; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Strychnine

2001
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Antiparasitic alkaloids from Psychotria klugii.
    Journal of natural products, 2003, Volume: 66, Issue:7

    Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leishmania donovani; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peru; Plants, Medicinal; Plasmodium falciparum; Psychotria; Quinazolines; Tumor Cells, Cultured

2003
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26

    Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Synthesis of novel 2-alkoxy-3-amino-3-arylpropan-1-ols and 5-alkoxy-4-aryl-1,3-oxazinanes with antimalarial activity.
    Journal of medicinal chemistry, 2009, Jul-09, Volume: 52, Issue:13

    Topics: Amino Alcohols; Animals; Antimalarials; Inhibitory Concentration 50; Oxazines; Parasitic Sensitivity Tests; Plasmodium falciparum; Propanols; Structure-Activity Relationship

2009
Antiplasmodial isoflavanones from the roots of Sophora mollis.
    Journal of natural products, 2009, Volume: 72, Issue:7

    Topics: Animals; Antimalarials; Isoflavones; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pakistan; Parasitic Sensitivity Tests; Plant Roots; Plants, Medicinal; Plasmodium falciparum; Sophora

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Artemisinin-quinoline hybrid-dimers: synthesis and in vitro antiplasmodial activity.
    Bioorganic & medicinal chemistry letters, 2010, Dec-01, Volume: 20, Issue:23

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dimerization; Drug Resistance; Plasmodium falciparum; Quinolines

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Synthesis of 2-(aminomethyl)aziridines and their microwave-assisted ring opening to 1,2,3-triaminopropanes as novel antimalarial pharmacophores.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Antimalarials; Aziridines; Microwaves; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Propylamines; Stereoisomerism; Structure-Activity Relationship

2011
Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybrids.
    Bioorganic & medicinal chemistry letters, 2011, Mar-15, Volume: 21, Issue:6

    Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Cell Survival; In Vitro Techniques; Plasmodium falciparum

2011
Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant Plasmodium falciparum and inhibit chloroquine transport via the P. falciparum chloroquine-resistance transporter (PfCRT).
    Journal of medicinal chemistry, 2011, Oct-13, Volume: 54, Issue:19

    Topics: Animals; Antimalarials; Biological Transport; Cell Survival; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Female; Malaria; Membrane Transport Proteins; Mice; Molecular Structure; Oocytes; Parasitemia; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Protozoan Proteins; Structure-Activity Relationship; Xenopus laevis

2011
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
    Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061

    Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites

2011
Synthesis, antimalarial activity and cytotoxicity of 10-aminoethylether derivatives of artemisinin.
    Bioorganic & medicinal chemistry, 2012, Aug-01, Volume: 20, Issue:15

    Topics: Animals; Antimalarials; Artemisinins; Cell Survival; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2012
Synthesis and in vitro antimalarial activity of a series of bisquinoline and bispyrrolo[1,2a]quinoxaline compounds.
    European journal of medicinal chemistry, 2012, Volume: 55

    Topics: Animals; Antimalarials; Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; CHO Cells; Cricetinae; Cricetulus; Humans; Quinolines; Quinoxalines; Solubility; Water

2012
Synthesis, characterization and antimalarial activity of quinoline-pyrimidine hybrids.
    Bioorganic & medicinal chemistry, 2013, Jan-01, Volume: 21, Issue:1

    Topics: Animals; Antimalarials; Cell Survival; CHO Cells; Cricetinae; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Pyrimidines; Quinolines

2013
Synthesis and antiplasmodial evaluation of novel (4-aminobutyloxy)quinolines.
    Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1

    Topics: Animals; Antimalarials; Catalysis; Cell Survival; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Plasmodium falciparum; Rhodium

2013
Synthesis of 2-aminomethyl-4-phenyl-1-azabicyclo[2.2.1]heptanes via LiAlH₄-induced reductive cyclization of 2-(4-chloro-2-cyano-2-phenylbutyl)aziridines and evaluation of their antimalarial activity.
    Bioorganic & medicinal chemistry letters, 2013, Mar-01, Volume: 23, Issue:5

    Topics: Aluminum Compounds; Antimalarials; Aziridines; Bridged Bicyclo Compounds; Cyclization; Heptanes; Humans; Ligands; Lithium Compounds; Molecular Docking Simulation; Stereoisomerism; Structure-Activity Relationship

2013
Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents.
    Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17

    Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Binding Sites; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Resistance; Half-Life; Humans; Microsomes, Liver; Molecular Docking Simulation; Plasmodium falciparum; Protein Structure, Tertiary; Rats; Structure-Activity Relationship; Tetrazoles

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vitro antimalarial activity, β-haematin inhibition and structure-activity relationships in a series of quinoline triazoles.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Antimalarials; Dose-Response Relationship, Drug; Hemeproteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship; Triazoles

2013
Synthesis of halogenated 4-quinolones and evaluation of their antiplasmodial activity.
    Bioorganic & medicinal chemistry letters, 2014, Feb-15, Volume: 24, Issue:4

    Topics: 4-Quinolones; Animals; Antimalarials; Cell Survival; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2014
Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds.
    ACS medicinal chemistry letters, 2013, Dec-12, Volume: 4, Issue:12

    Topics:

2013
Pentacycloundecylamines and conjugates thereof as chemosensitizers and reversed chloroquine agents.
    Bioorganic & medicinal chemistry letters, 2014, Dec-01, Volume: 24, Issue:23

    Topics: Amines; Antimalarials; Chloroquine; Humans; Malaria; Molecular Structure

2014
Synthesis and in vitro biological evaluation of dihydroartemisinyl-chalcone esters.
    European journal of medicinal chemistry, 2015, Jan-27, Volume: 90

    Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; Humans; MCF-7 Cells; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2015
Synthesis of functionalized 3-, 5-, 6- and 8-aminoquinolines via intermediate (3-pyrrolin-1-yl)- and (2-oxopyrrolidin-1-yl)quinolines and evaluation of their antiplasmodial and antifungal activity.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Aminoquinolines; Antifungal Agents; Antimalarials; Aspergillus flavus; Dose-Response Relationship, Drug; Parasitic Sensitivity Tests; Plasmodium falciparum; Rhodotorula; Structure-Activity Relationship

2015
Syntheses and in Vitro Antiplasmodial Activity of Aminoalkylated Chalcones and Analogues.
    Journal of natural products, 2015, Aug-28, Volume: 78, Issue:8

    Topics: Animals; Antimalarials; Cell Survival; Chalcones; Chloroquine; CHO Cells; Combinatorial Chemistry Techniques; Cricetinae; Cricetulus; Drug Resistance; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2015
Antimalarial benzoheterocyclic 4-aminoquinolines: Structure-activity relationship, in vivo evaluation, mechanistic and bioactivation studies.
    Bioorganic & medicinal chemistry, 2015, Sep-01, Volume: 23, Issue:17

    Topics: Aminoquinolines; Animals; Antimalarials; Benzene Derivatives; Humans; Malaria; Malaria, Falciparum; Mice; Mice, Inbred C57BL; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship

2015
Polycyclic amines as chloroquine resistance modulating agents in Plasmodium falciparum.
    Bioorganic & medicinal chemistry letters, 2016, Feb-15, Volume: 26, Issue:4

    Topics: Adamantane; Amines; Animals; Antimalarials; Calcium Channels; Cell Survival; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Drug Resistance; Inhibitory Concentration 50; Plasmodium falciparum; Protein Binding; Structure-Activity Relationship

2016
Indolyl-3-ethanone-α-thioethers: A promising new class of non-toxic antimalarial agents.
    European journal of medicinal chemistry, 2016, May-23, Volume: 114

    Topics: Antimalarials; Dose-Response Relationship, Drug; HeLa Cells; Humans; Indoles; Malaria; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Sulfides

2016
Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities.
    Bioorganic & medicinal chemistry letters, 2016, 07-01, Volume: 26, Issue:13

    Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Decoquinate; Drug Resistance, Multiple; Emetine; Humans; Inhibitory Concentration 50; Plasmodium falciparum; Quinolones

2016
Synthesis and biological evaluation of a series of non-hemiacetal ester derivatives of artemisinin.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Artemisinins; Cell Line, Tumor; Chemistry Techniques, Synthetic; CHO Cells; Cricetinae; Cricetulus; Drug Design; Esters; Humans; Plasmodium falciparum

2016
Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: Amides; Antimalarials; Chloroquine; Drug Resistance; Esters; Fusidic Acid; Plasmodium falciparum; Structure-Activity Relationship

2017
4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice.
    Journal of medicinal chemistry, 2017, 12-28, Volume: 60, Issue:24

    Topics: Administration, Oral; Aminopyridines; Aminoquinolines; Animals; Antimalarials; Cell Membrane Permeability; Chloroquine; CHO Cells; Cricetulus; Drug Evaluation, Preclinical; Drug Resistance, Microbial; ERG1 Potassium Channel; Hemeproteins; Humans; Malaria; Male; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Solubility; Structure-Activity Relationship

2017
Pyrimidine-chloroquinoline hybrids: Synthesis and antiplasmodial activity.
    European journal of medicinal chemistry, 2018, Mar-25, Volume: 148

    Topics: Animals; Antiprotozoal Agents; Binding Sites; Chlorocebus aethiops; Chloroquine; DNA; Drug Resistance; Hemin; Plasmodium falciparum; Pyrimidines; Vero Cells

2018
Adamantane amine-linked chloroquinoline derivatives as chloroquine resistance modulating agents in Plasmodium falciparum.
    Bioorganic & medicinal chemistry letters, 2018, 05-01, Volume: 28, Issue:8

    Topics: Adamantane; Aminoquinolines; Animals; Antimalarials; CHO Cells; Cricetulus; Drug Resistance, Microbial; Erythrocytes; Humans; Inhibitory Concentration 50; Molecular Structure; Plasmodium falciparum

2018
Identification of steroid-like natural products as antiplasmodial agents by 2D and 3D similarity-based virtual screening.
    MedChemComm, 2017, Jun-01, Volume: 8, Issue:6

    Topics:

2017
Hemozoin inhibiting 2-phenylbenzimidazoles active against malaria parasites.
    European journal of medicinal chemistry, 2018, Nov-05, Volume: 159

    Topics: Antimalarials; Benzimidazoles; Dose-Response Relationship, Drug; Hemeproteins; Malaria, Falciparum; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2018
Antiplasmodial imidazopyridazines: structure-activity relationship studies lead to the identification of analogues with improved solubility and hERG profiles.
    MedChemComm, 2018, Oct-01, Volume: 9, Issue:10

    Topics:

2018
Incorporation of an intramolecular hydrogen bonding motif in the side chain of antimalarial benzimidazoles.
    MedChemComm, 2019, Mar-01, Volume: 10, Issue:3

    Topics:

2019
Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids: Antimicrobial evaluation and mechanistic insights.
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Anti-Bacterial Agents; Antimalarials; Benzimidazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Ferrous Compounds; Malaria; Mice; Molecular Structure; Mycobacterium tuberculosis; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship

2019
Synthesis and biological evaluation of bis-N
    Bioorganic & medicinal chemistry letters, 2020, 03-01, Volume: 30, Issue:5

    Topics: Antifungal Agents; Antitubercular Agents; Catalytic Domain; Coumarins; HeLa Cells; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Hydrazines; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Protein Binding; Trypanocidal Agents; Trypanosoma brucei brucei

2020
Synthesis and biological evaluation of novel quinoline-piperidine scaffolds as antiplasmodium agents.
    European journal of medicinal chemistry, 2020, Jul-15, Volume: 198

    Topics: Antimalarials; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Piperidines; Plasmodium falciparum; Quinolines; Structure-Activity Relationship

2020
Design, synthesis and biological evaluation of mono- and bisquinoline methanamine derivatives as potential antiplasmodial agents.
    Bioorganic & medicinal chemistry letters, 2021, 04-15, Volume: 38

    Topics: Antimalarials; Dose-Response Relationship, Drug; Drug Design; Methylamines; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship

2021
[Amebiasis 2].
    Medizinische Klinik, 1976, Dec-17, Volume: 71, Issue:51-52

    Topics: Amebiasis; Chloroquine; Diagnosis, Differential; Emetine; Feces; Humans; Liver Abscess, Amebic; Metronidazole; Radionuclide Imaging; Serologic Tests; Tomography, X-Ray; Ultrasonography

1976
Amoebic liver abscess presenting as obstructive jaundice--a case report.
    JPMA. The Journal of the Pakistan Medical Association, 1976, Volume: 26, Issue:9

    Topics: Adult; Chloroquine; Cholestasis; Diagnosis, Differential; Emetine; Humans; Liver Abscess, Amebic; Male; Metronidazole; Pakistan

1976
Antiamoebic activity of drugs given singly and in combination against axenically grown Entamoeba histolytica.
    Archivos de investigacion medica, 1978, Volume: 9 Suppl 1

    Topics: Amebicides; Chloroquine; Culture Media; Drug Combinations; Emetine; Entamoeba; Entamoeba histolytica; Iodoquinol; Nitroimidazoles; Tetracycline

1978
Ventricular tachycardia in a patient on dehydroemetine and chloroquine for amoebic liver abscess.
    The Medical journal of Australia, 1979, May-05, Volume: 1, Issue:9

    Topics: Adult; Chloroquine; Electrocardiography; Emetine; Heart Ventricles; Humans; Liver Abscess, Amebic; Male; Tachycardia

1979
[Choledochal obstruction due to Fasciola hepatica (author's transl)].
    Medicina clinica, 1979, Dec-15, Volume: 73, Issue:10

    Topics: Chloroquine; Cholecystectomy; Cholecystitis; Cholelithiasis; Cholestasis; Common Bile Duct Diseases; Emetine; Fasciola hepatica; Fascioliasis; Female; Humans; Middle Aged

1979
Amebic liver abscess in childhood.
    Clinical pediatrics, 1975, Volume: 14, Issue:2

    Topics: Aortography; Chloroquine; Emetine; Entamoeba histolytica; Humans; Infant; Iodoquinol; Liver Abscess, Amebic; Male; Metronidazole; Niridazole; Radionuclide Imaging; Tetracycline

1975
[Biological diagnosis of malaria and amebiasis].
    Schweizerische medizinische Wochenschrift, 1977, May-07, Volume: 107, Issue:18

    Topics: Acetamides; Amebiasis; Chloroquine; Emetine; Entamoeba histolytica; Feces; Humans; Malaria; Methods; Nitroimidazoles; Primaquine; Quinine; Serologic Tests

1977
[Prevention and therapy of malaria and amebiasis].
    Schweizerische medizinische Wochenschrift, 1977, May-07, Volume: 107, Issue:18

    Topics: Acetamides; Amebiasis; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Emetine; Humans; Malaria; Nitroimidazoles; Protective Devices; Pyrimethamine; Sulfadoxine; Tetracycline

1977
Letter: Amebic liver abscess.
    JAMA, 1976, Apr-05, Volume: 235, Issue:14

    Topics: Chloroquine; Drug Therapy, Combination; Emetine; Humans; Liver Abscess, Amebic; Tetracyclines

1976
The treatment of amebiasis. A recurrent agony.
    JAMA, 1976, Feb-02, Volume: 235, Issue:5

    Topics: Amebiasis; Amebicides; Chloroquine; Drug Therapy, Combination; Dysentery, Amebic; Emetine; Humans; Iodoquinol; Legislation, Drug; Liver Abscess, Amebic; Metronidazole; Recurrence; United States; United States Food and Drug Administration

1976
Amebic abscess of the liver and spleen in pregnancy and the puerperium.
    Obstetrics and gynecology, 1975, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Amebiasis; Chloroquine; Emetine; Female; Humans; Infant, Newborn; Liver Abscess, Amebic; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; Puerperal Disorders; Radionuclide Imaging; Splenic Diseases

1975
Amoebic liver abscees presenting as obstructive jaundice: a case report.
    The Journal of tropical medicine and hygiene, 1975, Volume: 78, Issue:6

    Topics: Amoeba; Biopsy, Needle; Chloroquine; Cholestasis; Diagnosis, Differential; Emetine; Humans; Liver Abscess, Amebic; Liver Diseases; Liver Function Tests; Male; Middle Aged; Pakistan; Serologic Tests

1975
Recurrent amebic abscess of the liver.
    JAMA, 1975, Apr-21, Volume: 232, Issue:3

    Topics: Adult; Antibody Formation; Biopsy, Needle; Chloroquine; Emetine; Humans; Liver Abscess, Amebic; Male; Radiography, Abdominal; Radiography, Thoracic; Radionuclide Imaging; Recurrence; Time Factors

1975
A refractory case of hepatic amoebiasis.
    Gastroenterology, 1976, Volume: 70, Issue:4

    Topics: Adult; Amebicides; Chloroquine; Dysentery, Amebic; Emetine; Humans; Liver Abscess, Amebic; Male; Metronidazole; Time Factors

1976
Susceptibility of an emetine-resistant mutant of Entamoeba histolytica to multiple drugs and to channel blockers.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Animals; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Chloroquine; Clone Cells; Drug Resistance; Emetine; Entamoeba histolytica; Furans; Iodoquinol; Ion Channels; Metronidazole; Mutation; Phenotype

1992
Newly synthesized class II MHC chains are required for VSV G presentation to CTL clones.
    Cellular immunology, 1992, Volume: 139, Issue:1

    Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Antigens, Viral; Brefeldin A; Chloroquine; Clone Cells; Cyclopentanes; Emetine; Glycoproteins; Histocompatibility Antigens Class II; Lymphocyte Cooperation; Membrane Glycoproteins; Mice; Recombinant Proteins; Solubility; T-Lymphocytes, Cytotoxic; Vesicular stomatitis Indiana virus; Viral Envelope Proteins

1992
Demonstration of MHC class II-restricted cytotoxic T lymphocytes in mice against herpes simplex virus.
    Immunology, 1990, Volume: 71, Issue:1

    Topics: Animals; Antigens, Differentiation; Cell Line; Chloroquine; Cytotoxicity, Immunologic; Emetine; Female; Herpes Simplex; Histocompatibility Antigens Class II; Lymph Nodes; Mice; Mice, Inbred BALB C; T-Lymphocytes, Cytotoxic

1990
In vitro effect of emetine and chloroquine on the macromolecular biosynthesis of murine thymus cells.
    Acta biochimica et biophysica Hungarica, 1987, Volume: 22, Issue:1

    Topics: Animals; Cell Survival; Chloroquine; DNA; Emetine; In Vitro Techniques; Macromolecular Substances; Male; Mice; Mice, Inbred Strains; Protein Biosynthesis; RNA; Thymus Gland

1987
Genotoxicity of amebicide and anthelmintic drugs in Escherichia coli pol A+/pol A-.
    Mutation research, 1987, Volume: 188, Issue:2

    Topics: Amebicides; Animals; Anthelmintics; Bacterial Proteins; Chloroquine; Clioquinol; DNA Polymerase I; Emetine; Escherichia coli; Hexylresorcinol; Iodoquinol; Male; Microbial Sensitivity Tests; Microsomes, Liver; Mutagenicity Tests; Pyrvinium Compounds; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Suspensions

1987
Effect of emetine and chloroquine on phagocytic processes of rat macrophages.
    Biochemical pharmacology, 1986, Sep-01, Volume: 35, Issue:17

    Topics: Animals; Carbon Radioisotopes; Cell Adhesion; Chloroquine; Cytoskeleton; Emetine; Glycolysis; Leucine; Macrophages; Phagocytosis; Protein Biosynthesis; Rats; Rats, Inbred Strains

1986
[Cardiotoxic drugs].
    Schweizerische medizinische Wochenschrift, 1973, Apr-28, Volume: 103, Issue:17

    Topics: Adult; Angina Pectoris; Anti-Bacterial Agents; Antipsychotic Agents; Chloroquine; Contraceptives, Oral; Death, Sudden; Electrocardiography; Emetine; Female; Heart Diseases; Humans; Imipramine; Middle Aged; Myocardial Infarction; Phenothiazines; Phenylbutazone

1973
Human fascioliasis in Shropshire.
    British medical journal, 1970, Aug-29, Volume: 3, Issue:5721

    Topics: Administration, Oral; Adolescent; Adult; Animals; Anthelmintics; Body Temperature; Chloroquine; Complement Fixation Tests; Disease Vectors; Emetine; Eosinophilia; Fascioliasis; Feces; Female; gamma-Globulins; Humans; Male; Middle Aged; Precipitin Tests; Pruritus; Splenic Diseases; Sulfides

1970
The amoebicidal, trichomonicidal, and antibacterial effects of niridazole in laboratory animals.
    Annals of the New York Academy of Sciences, 1969, Oct-06, Volume: 160, Issue:2

    Topics: Amebiasis; Amebicides; Amoeba; Animals; Anthelmintics; Antimony; Antiprotozoal Agents; Chloroquine; Clioquinol; Cricetinae; Dysentery, Bacillary; Emetine; Enterobacteriaceae Infections; Furazolidone; Imidazoles; Intestinal Diseases, Parasitic; Liver Abscess, Amebic; Metronidazole; Mice; Quinacrine; Salmonella Infections; Sulfonamides; Sulfones; Tartrates; Tetracycline; Thiazoles; Trichomonas Infections

1969
Subdiaphragmatic infection.
    Diseases of the chest, 1967, Volume: 52, Issue:2

    Topics: Adult; Bacteria; Blood Cell Count; Chloroquine; Diaphragm; Drainage; Emetine; Entamoeba histolytica; Feces; Female; Fluoroscopy; Humans; Infections; Inhalation; Male; Middle Aged; Pneumoperitoneum, Artificial; Suppuration

1967
Hepatic abscess: review of seven patients seen at Wilford Hall USAF Hospital, 1956-1966.
    Archives of surgery (Chicago, Ill. : 1960), 1968, Volume: 96, Issue:1

    Topics: Adolescent; Adult; Chloroquine; Drainage; Emetine; Entamoeba histolytica; Fluoroscopy; Gold Isotopes; Humans; Liver Abscess; Liver Abscess, Amebic; Male; Military Medicine; Radionuclide Imaging

1968
Amebic liver abscess.
    The American journal of digestive diseases, 1968, Volume: 13, Issue:9

    Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Sedimentation; Chloroquine; Emetine; Entamoeba histolytica; Giardia; Hemoglobinometry; Hepatomegaly; Humans; Iodine Radioisotopes; Leukocyte Count; Liver Abscess, Amebic; Male; Military Medicine; Radionuclide Imaging; Rose Bengal; Sulfobromophthalein; Tetracycline; Vietnam

1968
[The amebic abscess of the liver. Clinical and therapeutic aspects].
    Schweizerische medizinische Wochenschrift, 1968, Jun-29, Volume: 98, Issue:26

    Topics: Adult; Aged; Amebicides; Blood Sedimentation; Chloroquine; Congo; Diagnosis, Differential; Drainage; Emetine; Feces; Female; Humans; Imidazoles; Iodized Oil; Leukocyte Count; Liver Abscess, Amebic; Male; Middle Aged; Proctoscopy; Punctures; Radiography; Tablets, Enteric-Coated; Thiazoles

1968
Amebic abscess of the liver. Experience with 15 cases in 3 and one-half years in California.
    The American journal of digestive diseases, 1969, Volume: 14, Issue:4

    Topics: Bacteria; California; Chloroquine; Diagnosis, Differential; Drainage; Emetine; Entamoeba histolytica; Humans; Liver Abscess, Amebic; Liver Function Tests; Lung; Mexico; Radiography; Radionuclide Imaging; Tetracycline; Travel

1969
[On the relations between Entamoeba histolytica, Laredo strains, Entamoeba invadens and Entamoeba moshkovskii evaluated according to their sensitivity to anti-amebic drugs].
    Giornale di malattie infettive e parassitarie, 1968, Volume: 20, Issue:3

    Topics: Amebicides; Antifungal Agents; Arsenicals; Chloroquine; Chlortetracycline; Emetine; Entamoeba; Entamoeba histolytica; Hydroxyquinolines; In Vitro Techniques

1968
Intracavitary I-131-labeled BSP as follow-up for management of amebic liver abscess.
    The American journal of gastroenterology, 1971, Volume: 55, Issue:1

    Topics: Adult; Chloroquine; Drainage; Emetine; Entamoeba histolytica; Follow-Up Studies; Humans; Iodine Radioisotopes; Liver Abscess, Amebic; Liver Function Tests; Male; Methods; Middle Aged; Radionuclide Imaging; Sulfobromophthalein

1971
Right lower lobe abscess in a Nigerian.
    Chest, 1972, Volume: 61, Issue:4

    Topics: Adult; Amebiasis; Chloroquine; Emetine; Entamoeba histolytica; Humans; Lung Abscess; Male; Radiography; Sputum

1972
[Medical treatment of amebiasis].
    Archivos de investigacion medica, 1972, Volume: 2

    Topics: Amebiasis; Amebicides; Arsenicals; Chloroquine; Emetine; Entamoeba histolytica; Evaluation Studies as Topic; Humans; Liver Abscess, Amebic; Metronidazole; Paromomycin; Quinolines

1972
Amebiasis presenting as an acute abdomen.
    American journal of surgery, 1974, Volume: 127, Issue:3

    Topics: Abdomen, Acute; Adult; Amebiasis; Cephalothin; Chloroquine; Diagnosis, Differential; Diagnostic Errors; Emetine; Entamoeba histolytica; Humans; Kanamycin; Liver Abscess, Amebic; Male; Middle Aged; Postoperative Complications; United States; Vietnam

1974
Amebic liver abscess following metronidazole therapy for amebic colitis.
    The American journal of tropical medicine and hygiene, 1974, Volume: 23, Issue:2

    Topics: Adult; Chloroquine; Dysentery, Amebic; Emetine; Entamoeba histolytica; Follow-Up Studies; Heart Diseases; Humans; Iodoquinol; Liver Abscess, Amebic; Male; Metronidazole; Neoplasms; Radionuclide Imaging; Time Factors; Vietnam

1974
Latest developments in the treatment of amebiasis.
    Advances in pharmacology and chemotherapy, 1972, Volume: 10

    Topics: Amebiasis; Amebicides; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Chloroquine; Dysentery, Amebic; Emetine; Entamoeba histolytica; Humans; Intestinal Diseases; Liver Abscess, Amebic; Metronidazole; Niridazole; Nitroimidazoles

1972
Acute suppurative amebic pericarditis.
    The American journal of cardiology, 1974, Volume: 34, Issue:1

    Topics: Acute Disease; Amebiasis; Blood Pressure; Cardiac Catheterization; Cardiac Tamponade; Cardiomegaly; Chloroquine; Drainage; Electrocardiography; Emetine; Entamoeba histolytica; Humans; Liver Abscess, Amebic; Male; Metronidazole; Pericarditis; Pericarditis, Constrictive; Pericardium; Radiography

1974
[Clinical aspects of amebic dysentery].
    Gastroenterologische Fortbildungskurse fur die Praxis, 1973, Volume: 3

    Topics: Acute Disease; Antibody Formation; Chloroquine; Complement Fixation Tests; Dysentery, Amebic; Emetine; Entamoeba histolytica; Hemagglutination Tests; Humans; Latex Fixation Tests; Metronidazole; Proctoscopy; Radiography; Radionuclide Imaging

1973
Diagnosis and treatment of intrahepatic abscess.
    The American surgeon, 1967, Volume: 33, Issue:10

    Topics: Adult; Aged; Angiography; Cephalothin; Chloroquine; Cholangiography; Drainage; Emetine; Female; Ganglionic Blockers; Humans; Kanamycin; Liver Abscess; Liver Abscess, Amebic; Male; Middle Aged; Radiography, Thoracic; Radionuclide Imaging; Tetracycline

1967
Hepatic amebic abscess. Unresponsiveness to combination of metronidazole and surgical drainage.
    JAMA, 1974, Jul-01, Volume: 229, Issue:1

    Topics: Administration, Oral; Adult; Chloroquine; Drainage; Emetine; Female; Humans; Injections, Intramuscular; Liver Abscess, Amebic; Metronidazole; Pregnancy; Pregnancy Complications, Infectious

1974
Myocarditis associated with primary amebic (Naegleria) meningoencephalitis.
    American journal of clinical pathology, 1974, Volume: 62, Issue:5

    Topics: Adolescent; Adult; Amoeba; Amphotericin B; Brain; Bronchopneumonia; Child; Chloroquine; Electrocardiography; Emetine; Eosinophils; Exudates and Transudates; Female; Hepatitis; Humans; Male; Meningoencephalitis; Metronidazole; Myocarditis; Myocardium; Penicillins; Pulmonary Edema; Sulfadiazine; Sulfisoxazole

1974
Hepatic amoebiasis at high altitude.
    International journal of biometeorology, 1974, Volume: 18, Issue:4

    Topics: Adult; Altitude; Chloroquine; Emetine; Evaluation Studies as Topic; Humans; India; Liver Abscess, Amebic; Male; Middle Aged; Military Personnel; Recurrence; Seasons

1974
Treatment of liver abscesses. A conservative surgical approach.
    American journal of surgery, 1973, Volume: 126, Issue:2

    Topics: Adult; Autopsy; Chloroquine; Drainage; Emetine; Humans; Iodoquinol; Liver Abscess; Liver Abscess, Amebic; Male; Metronidazole; Radionuclide Imaging; Tetracycline

1973
Situs inversus with amoebic liver abscess.
    The Journal of tropical medicine and hygiene, 1973, Volume: 76, Issue:7

    Topics: Adult; Chloroquine; Dextrocardia; Emetine; Humans; Inhalation; Iodoquinol; Liver Abscess, Amebic; Liver Function Tests; Male; Situs Inversus

1973
Experiences in the therapy of amebic liver abscess on Taiwan.
    The American journal of tropical medicine and hygiene, 1973, Volume: 22, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Chloroquine; Chlortetracycline; Emetine; Female; Humans; Inhalation; Injections, Intramuscular; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; Taiwan

1973
Amebic abscess of the liver.
    International surgery, 1973, Volume: 58, Issue:2

    Topics: Adult; Chloroquine; Emetine; Humans; India; Liver Abscess, Amebic; Male; Middle Aged

1973
The use of combined ultrasonic and isotope scanning in the diagnosis of amoebic liver disease.
    Gut, 1973, Volume: 14, Issue:1

    Topics: Adult; Alkaline Phosphatase; Bilirubin; Chloroquine; Emetine; Humans; Liver Abscess, Amebic; Liver Function Tests; Male; Metronidazole; Middle Aged; Radionuclide Imaging; Technetium; Ultrasonography

1973
Concepts in hepatic amoebiasis.
    The Journal of tropical medicine and hygiene, 1973, Volume: 76, Issue:2

    Topics: Biopsy; Chloroquine; Diarrhea; Emetine; Humans; Leukocytosis; Liver Abscess, Amebic; Radiography

1973
Failure of metronidazole to cure hepatic amebic abscess.
    The New England journal of medicine, 1973, Jun-28, Volume: 288, Issue:26

    Topics: Adult; Chloroquine; Emetine; Humans; Liver Abscess, Amebic; Male; Metronidazole

1973
Hepatic amebic abscess not responding to metronidazole.
    The New England journal of medicine, 1973, Aug-16, Volume: 289, Issue:7

    Topics: Adult; Chloroquine; Emetine; Female; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged

1973
Amebic abscess of the liver. Treatment failure with metronidazole.
    JAMA, 1973, Jun-04, Volume: 224, Issue:10

    Topics: Administration, Oral; Adult; Chloroquine; Emetine; Humans; Liver Abscess, Amebic; Liver Function Tests; Lung; Male; Metronidazole; Pleural Effusion; Radiography; Time Factors

1973
Treatment of amoebiasis.
    The Journal of the Egyptian Public Health Association, 1973, Volume: 48, Issue:3

    Topics: Acute Disease; Amebiasis; Anti-Bacterial Agents; Chloroquine; Chronic Disease; Dysentery, Amebic; Egypt; Emetine; Humans; Liver Abscess, Amebic; Metronidazole

1973
[Present orientation in treatment of amoebic abscess (author's transl)].
    The Journal of the Egyptian Public Health Association, 1973, Volume: 48, Issue:3

    Topics: Chloroquine; Drainage; Drug Therapy, Combination; Emetine; Hepatectomy; Humans; Liver Abscess, Amebic

1973
Resolution of amoebic liver abscess, studied by serial liver scanning.
    The Journal of the Association of Physicians of India, 1974, Volume: 22, Issue:3

    Topics: Chloroquine; Emetine; Humans; Iodine Radioisotopes; Liver Abscess, Amebic; Radionuclide Imaging

1974
Amebic liver abscesses.
    Rocky Mountain medical journal, 1974, Volume: 71, Issue:7

    Topics: Adult; Chloramphenicol; Chloroquine; Dysentery, Amebic; Emetine; Humans; Liver Abscess, Amebic; Male; Metronidazole

1974
[Therapy of amebiasis].
    Der Internist, 1968, Volume: 9, Issue:8

    Topics: Amebiasis; Anti-Bacterial Agents; Chloroquine; Diet Therapy; Dysentery, Amebic; Emetine; Humans; Liver Abscess, Amebic; Physical Therapy Modalities

1968
Treatment of amebic abscess of the liver.
    The American journal of gastroenterology, 1969, Volume: 51, Issue:4

    Topics: Chloroquine; Drainage; Emetine; Glaucarubin; Humans; Iodoquinol; Liver Abscess, Amebic; Paromomycin; Tetracycline

1969
Trials of BT 436 in amoebiasis.
    Zeitschrift fur Tropenmedizin und Parasitologie, 1967, Volume: 18, Issue:3

    Topics: Amebiasis; Amebicides; Chloroquine; Drug Synergism; Dysentery, Amebic; Emetine; Hydroxyquinolines; Iodoquinol; Liver Abscess, Amebic; Tablets

1967
[Apropos of a case of hepatic distomatosis due to Fasciola gigantica contracted in Cameroon].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1968, Volume: 61, Issue:2

    Topics: Abscess; Adult; Anxiety; Buttocks; Cameroon; Chloroquine; Delirium; Emetine; Eosinophilia; Fasciola; Female; Humans; Immunodiffusion; Liver Diseases; Phenanthrolines; Prednisone; Quinones; Serologic Tests; Strongyloidiasis; Trematode Infections

1968
Sequential liver scanning.
    Journal of surgical oncology, 1969, Volume: 1, Issue:3

    Topics: Adult; Breast Neoplasms; Chloroquine; Colonic Neoplasms; Dactinomycin; Emetine; Estrogens; Female; Fluorouracil; Gold Colloid, Radioactive; Humans; Liver Abscess, Amebic; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Radionuclide Imaging; Thiotepa

1969
Diagnosis and treatment of rupture of amebic abscess of the liver into the pericardium.
    The Journal of thoracic and cardiovascular surgery, 1972, Volume: 64, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Child, Preschool; Chloroquine; Drainage; Electrocardiography; Emetine; Female; Humans; Infant; Liver Abscess, Amebic; Male; Middle Aged; Pericardium; Radiography; Rupture, Spontaneous

1972
Amebic pericarditis.
    JAMA, 1972, May-15, Volume: 220, Issue:7

    Topics: Adult; Amebiasis; Angiocardiography; Biopsy; Cardiac Tamponade; Chloroquine; Emetine; Female; Hemagglutination Tests; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; Pericardial Effusion; Pericarditis; Radionuclide Imaging; Rupture

1972
[Advances in the treatment of amebic liver abscess in children].
    Archivos de investigacion medica, 1972, Volume: 3, Issue:2

    Topics: Adolescent; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Chloroquine; Drainage; Emetine; Evaluation Studies as Topic; Female; Humans; Infant; Laparotomy; Liver Abscess, Amebic; Male; Metronidazole

1972
[Clinical picture of the amebic liver abscess].
    Medizinische Klinik, 1971, Nov-05, Volume: 66, Issue:45

    Topics: Adult; Amoeba; Autopsy; Blood Sedimentation; Chloroquine; Diagnosis, Differential; Emetine; Feces; Humans; Liver Abscess, Amebic; Male; Medical History Taking; Metronidazole; Palpation; Prognosis; Punctures; Radiography; Radionuclide Imaging

1971
Properties distinguishing mitochondrial and synaptosomal protein synthesis.
    Biochemical and biophysical research communications, 1971, Oct-15, Volume: 45, Issue:2

    Topics: Animals; Brain; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Chloroquine; Cycloheximide; Depression, Chemical; Drug Antagonism; Emetine; Leucine; Mice; Mitochondria; Nerve Endings; Nerve Tissue Proteins; Synaptic Vesicles; Synaptosomes

1971
The use of niridazole alone and in combination with other amoebicides in amoebic dysentery and amoebic liver abscess.
    Annals of the New York Academy of Sciences, 1969, Oct-06, Volume: 160, Issue:2

    Topics: Amebicides; Anthelmintics; Chloroquine; Dysentery, Amebic; Electrocardiography; Emetine; Humans; Imidazoles; Intestines; Liver; Liver Diseases, Parasitic; Metronidazole; Thiazoles

1969
Comparative study of the effects of ambilhar and a combination of dehydroemetine and chloroquine in amoebic liver abscess.
    Annals of the New York Academy of Sciences, 1969, Oct-06, Volume: 160, Issue:2

    Topics: Adult; Aged; Anthelmintics; Blood Sedimentation; Chloroquine; Electrocardiography; Emetine; Female; Hemoglobinometry; Humans; Imidazoles; Leukocyte Count; Liver Abscess, Amebic; Male; Middle Aged; Mucoproteins; Thiazoles

1969
Amoebic pericarditis.
    The Quarterly journal of medicine, 1966, Volume: 35, Issue:138

    Topics: Adolescent; Adult; Amebiasis; Chloroquine; Electrocardiography; Emetine; Female; Humans; Inhalation; Iodoquinol; Liver Abscess, Amebic; Male; Middle Aged; Pericarditis; Pericarditis, Constrictive

1966
Primary amebic meningoencephalitis.
    The New England journal of medicine, 1969, Dec-11, Volume: 281, Issue:24

    Topics: Adolescent; Amebiasis; Amoeba; Autopsy; Brain; Cerebrospinal Fluid; Chloroquine; Diagnosis, Differential; Emetine; Female; Humans; Lung; Meningoencephalitis; Metronidazole; Myocarditis; Neurologic Manifestations; Pulmonary Edema; Spinal Puncture; Spleen; Swimming; Virginia

1969
[Pulmonary paragonimiasis or distomatosis (apropos of 8 cases)].
    Le Poumon et le coeur, 1969, Volume: 25, Issue:8

    Topics: Chloroquine; Emetine; Humans; Lung Diseases, Parasitic; Paragonimiasis; Radiography

1969
Metronidazole and niridazole combined with dehydroemetine in treatment of children with amoebic liver abscess.
    Archives of disease in childhood, 1970, Volume: 45, Issue:240

    Topics: Amebicides; Anthelmintics; Child; Child, Preschool; Chloroquine; Drug Synergism; Electrocardiography; Emetine; Female; Humans; Infant; Liver; Liver Abscess, Amebic; Male; Metronidazole

1970
Drugs for dysentery.
    British medical journal, 1970, Apr-04, Volume: 2, Issue:5700

    Topics: Adult; Amebicides; Child; Chloroquine; Drug Resistance, Microbial; Dysentery, Amebic; Dysentery, Bacillary; Emetine; Humans; Liver Abscess, Amebic; Metronidazole; Nalidixic Acid; Streptomycin; Sulfonamides; Tetracycline

1970
Fascioliasis--a large outbreak.
    British medical journal, 1970, Aug-29, Volume: 3, Issue:5721

    Topics: Adolescent; Adult; Aged; Blood Cell Count; Child; Chloroquine; Complement Fixation Tests; Disease Outbreaks; Emetine; Fasciola hepatica; Fascioliasis; Feces; Female; Humans; Liver Function Tests; Male; Middle Aged; Wales

1970
[Present treatment of amebiasis].
    La Presse medicale, 1970, Nov-21, Volume: 78, Issue:49

    Topics: Amebicides; Chloroquine; Dysentery, Amebic; Emetine; Humans; Liver Abscess, Amebic; Metronidazole; Paromomycin

1970
[Comparative study of drugs used in the treatment of acute amebic hepatic abscess].
    Archivos de investigacion medica, 1970, Volume: 1

    Topics: Chloroquine; Emetine; Evaluation Studies as Topic; Humans; Liver Abscess, Amebic; Metronidazole

1970
Amebiasis. Weekly clinical conference of the section of gastroenterology of the University of Michigan.
    The American journal of digestive diseases, 1971, Volume: 16, Issue:1

    Topics: Amebiasis; Chloroquine; Climate; Disease Outbreaks; Emetine; Humans; Metronidazole; Paromomycin; Temperature

1971
Amoebicides.
    The Practitioner, 1971, Volume: 206, Issue:231

    Topics: Amebicides; Chloroquine; Dysentery, Amebic; Emetine; Humans; Imidazoles; Metronidazole; Oxytetracycline

1971
Pleuropulmonary amebiasis.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1971, Volume: 111, Issue:3

    Topics: Adult; Amebiasis; Chloroquine; Diagnosis, Differential; Emetine; Empyema; Humans; Liver Abscess, Amebic; Lung Abscess; Lung Diseases, Parasitic; Male; Middle Aged; Pleural Diseases; Pneumonia; Radiography

1971
[Peritonitis in perforations of amebic abscesses in the liver].
    Khirurgiia, 1967, Volume: 43, Issue:1

    Topics: Adult; Chloroquine; Emetine; Female; Humans; Liver Abscess, Amebic; Male; Middle Aged; Peritonitis

1967
[Clinical picture and treatment of amebiasis of the liver].
    Khirurgiia, 1967, Volume: 43, Issue:1

    Topics: Adolescent; Adult; Antiprotozoal Agents; Child; Chloroquine; Emetine; Female; Humans; Liver Abscess, Amebic; Male

1967
Emetine hydrochloride and dehydroemetine combined with chloroquine in the treatment of children with amoebic liver abscess.
    Archives of disease in childhood, 1968, Volume: 43, Issue:227

    Topics: Child; Child, Preschool; Chloroquine; Electrocardiography; Emetine; Follow-Up Studies; Humans; Infant; Liver Abscess, Amebic

1968
[Amebic liver abscess].
    Medizinische Klinik, 1968, Aug-02, Volume: 63, Issue:31

    Topics: Adult; Ampicillin; Chloramphenicol; Chloroquine; Diagnosis, Differential; Emetine; Humans; Liver; Liver Abscess, Amebic; Male; Nitrofurantoin; Penicillins; Radiography, Thoracic; Radionuclide Imaging; Ureteral Calculi

1968
[Clinical observations in patients with acute amebic dysentery].
    Medizinische Klinik, 1968, Jul-05, Volume: 63, Issue:27

    Topics: Acute Disease; Chloroquine; Colitis, Ulcerative; Diagnosis, Differential; Dysentery, Amebic; Emetine; Feces; Female; Humans; Hydroxyquinolines; Hyperbilirubinemia; Liver Diseases; Male; Transaminases

1968
Rapid diagnostic approach to amebic liver abscess.
    The American journal of digestive diseases, 1969, Volume: 14, Issue:4

    Topics: Adult; Chloroquine; Complement Fixation Tests; Drainage; Emetine; Gold Isotopes; Hemagglutination Tests; Humans; Liver Abscess, Amebic; Liver Function Tests; Male; Methods; Radionuclide Imaging

1969
A comparative trial of dehydroemetine, emetine hydrochloride and chloroquine in the treatment of amoebic liver abscess.
    Annals of tropical medicine and parasitology, 1965, Volume: 59, Issue:4

    Topics: Chloroquine; Electrocardiography; Emetine; Humans; Liver Abscess, Amebic

1965
Thoracic repercussions of amebiasis.
    The Journal of thoracic and cardiovascular surgery, 1966, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Aged; Amebiasis; Chloroquine; Diagnosis, Differential; Dysentery, Amebic; Emetine; Female; Humans; Male; Middle Aged; Radiography; Thoracic Diseases

1966
Effect of chloroquine and emetine on rat liver microsomal enzyme system.
    Journal of postgraduate medicine, 1966, Volume: 12, Issue:2

    Topics: Animals; Chloroquine; Emetine; In Vitro Techniques; Liver; Male; Rats

1966
Amoebiasis in the New Guinea Western Highlands.
    The Medical journal of Australia, 1966, Dec-03, Volume: 2, Issue:23

    Topics: Adolescent; Adult; Child; Child, Preschool; Chloroquine; Diarrhea; Diarrhea, Infantile; Dysentery, Amebic; Emetine; Female; Humans; Infant; Male; New Guinea; Tetracycline

1966
Emetine hydrochloride and chloroquine in the treatment of children with amoebic liver abscess.
    Archives of disease in childhood, 1966, Volume: 41, Issue:219

    Topics: Black or African American; Black People; Child; Child, Preschool; Chloroquine; Emetine; Female; Humans; Infant; Liver Abscess, Amebic; Male; South Africa

1966
Pleuropulmonary amoebiasis.
    The Journal of the Association of Physicians of India, 1966, Volume: 14, Issue:10

    Topics: Adult; Amebiasis; Chloroquine; Emetine; Empyema; Humans; Lung Diseases, Parasitic; Male; Middle Aged

1966
Amebic liver abscess.
    Southern medical journal, 1967, Volume: 60, Issue:3

    Topics: Adolescent; Adult; Aged; Amebiasis; Child; Chloroquine; Emetine; Feces; Female; Georgia; Humans; Korea; Liver Abscess, Amebic; Male; Middle Aged; Radiography

1967
The chemotherapy of amoebiasis.
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:5

    Topics: Acetanilides; Amebiasis; Amebicides; Arsenicals; Carrier State; Chloroquine; Dysentery, Amebic; Emetine; Entamoebiasis; Erythromycin; Furans; Humans; Hydroxyquinolines; Metronidazole; Nitroimidazoles; Paromomycin; Tetracyclines; Tinidazole

1980
Hepatic amebiasis: experience in the therapy of 56 cases.
    Acta medica portuguesa, 1981, Issue:Suppl 2

    Topics: Adult; Chloroquine; Drug Therapy, Combination; Emetine; Female; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; Retrospective Studies

1981
Diagnosis and management of amebic liver abscess in children.
    The Western journal of medicine, 1984, Volume: 140, Issue:6

    Topics: Adult; Child, Preschool; Chloroquine; Emetine; Female; Humans; Infant; Liver Abscess, Amebic; Male; Metronidazole; Ultrasonography

1984
Action of antiamoebic drugs on hepatic microsomal drug-metabolizing enzymes of hamster infected with virulent Entamoeba histolytica.
    The Indian journal of medical research, 1983, Volume: 78

    Topics: Amebicides; Animals; Chloroquine; Cricetinae; Emetine; Entamoeba histolytica; Liver Abscess, Amebic; Mesocricetus; Metronidazole; Microsomes, Liver

1983
A model system for measuring comparative toxicities of cardiotoxic drugs with cultured rat heart myocytes, endothelial cells and fibroblasts. I. Emetine, chloroquine and metronidazole.
    Toxicology, 1984, Volume: 33, Issue:2

    Topics: Animals; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Emetine; Endothelium; Fibroblasts; Heart; Metronidazole; Myocardium; Rats

1984
Amebiasis.
    Antibiotics and chemotherapy, 1981, Volume: 30

    Topics: Acetamides; Amebiasis; Amebicides; Chloroquine; Emetine; Entamoebiasis; Humans; Imidazoles; Intestines; Liver; Oxyquinoline

1981
Inhibition of the metabolism and motility of human spermatozoa by various alkaloids.
    Contraception, 1982, Volume: 25, Issue:1

    Topics: Antimalarials; Carbon Dioxide; Chloroquine; Emetine; Humans; Lactates; Lactic Acid; Male; Quinacrine; Quinine; Sperm Motility; Spermatozoa

1982
[Amebic liver abscess: review of 13 cases].
    Medicina clinica, 1995, Oct-28, Volume: 105, Issue:14

    Topics: Adult; Age Factors; Amebicides; Chloroquine; Drug Therapy, Combination; Emetine; Female; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; Sex Factors; Spain; Tinidazole

1995
Degradation of human thyroperoxidase in the endoplasmic reticulum involves two different pathways depending on the folding state of the protein.
    The Journal of biological chemistry, 2000, May-26, Volume: 275, Issue:21

    Topics: Acetylcysteine; Ammonium Chloride; Animals; Antibodies, Monoclonal; Chloroquine; CHO Cells; Cricetinae; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Emetine; Endoplasmic Reticulum; Humans; Multienzyme Complexes; Peroxidase; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Folding; Thyroid Gland

2000
[Further contribution on chloroquin (Resochin Bayer) therapy in emetine-resistant amebic hepatitis].
    Acta medica Italica di malattie infettive e parassitarie, 1952, Volume: 7, Issue:10

    Topics: Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Hepatitis; Humans; Liver Diseases

1952
The diagnosis and treatment of amebic dysentery.
    Journal of the American Geriatrics Society, 1953, Volume: 1, Issue:7

    Topics: Amebiasis; Anti-Bacterial Agents; Arsanilic Acid; Chloroquine; Dysentery, Amebic; Emetine; Humans; Iodoquinol; Sulfanilamide; Sulfanilamides; Sulfonamides

1953
Chloroquine in amoebic hepatitis; with a report of 14 cases.
    Journal of the Indian Medical Association, 1954, Volume: 23, Issue:6

    Topics: Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Hepatitis; Humans; Liver Abscess, Amebic

1954
[Resochin in the treatment of amebic hepatitis and liver abscess].
    Zeitschrift fur Tropenmedizin und Parasitologie, 1955, Volume: 6, Issue:2

    Topics: Abscess; Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Hepatitis; Humans; Liver Abscess; Liver Abscess, Amebic

1955
The comparative value of emetine and chloroquine in amebic liver abscess.
    The American journal of tropical medicine and hygiene, 1958, Volume: 7, Issue:2

    Topics: Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Humans; Liver Abscess, Amebic

1958
[Chloroquine therapy of diffuse emetine-resistant amebic colliquative hepatitis].
    La Riforma medica, 1958, Aug-02, Volume: 72, Issue:31

    Topics: Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Hepatitis; Hepatitis A; Humans; Liver Abscess, Amebic

1958
[Mixed treatment with emetine & chloroquine of amebic hepatitis; elective indications & advantages].
    Minerva medica, 1959, Feb-07, Volume: 50, Issue:11

    Topics: Amebiasis; Chloroquine; Emetine; Hepatitis; Humans; Liver Abscess, Amebic

1959
[OBSERVATIONS on the therapeutic value of chloroquine and chloroquine combined with emetine in the treatment of 160 cases of paragonimiasis].
    Zhonghua nei ke za zhi, 1959, Volume: 7, Issue:3

    Topics: Chloroquine; Emetine; Humans; Liver Diseases, Parasitic; Paragonimiasis

1959
Successful treatment of hepatic and splenic amebic abscesses with atabrine after failure of emetine, chloroquine and terramycin.
    The Journal of the Egyptian Medical Association, 1960, Volume: 43

    Topics: Amebiasis; Chloroquine; Disease; Dysentery, Amebic; Emetine; Humans; Liver Abscess; Oxytetracycline; Quinacrine; Spleen

1960
Chloroquine compared with chloroquine and emetine combined in ameblic liver abscess.
    The American journal of tropical medicine and hygiene, 1959, Volume: 8

    Topics: Abscess; Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Humans; Liver Abscess

1959
[A case of autochthonous, emetine-resistant, recurrent and spontaneously regressive hepatic amebiasis].
    Revue internationale d'hepatologie, 1963, Volume: 13

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Chloroquine; Emetine; Gold Colloid; Gold Colloid, Radioactive; Humans; Liver Abscess; Liver Abscess, Amebic; Radiometry

1963
Amoebic disease of the liver.
    The Manchester medical gazette, 1963, Volume: 42(2)

    Topics: Chloroquine; Emetine; Humans; Liver Abscess; Liver Abscess, Amebic

1963
Clinical observation of liver abscess.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1962, Jun-28, Volume: 61

    Topics: Chloroquine; Emetine; Humans; Liver Abscess; Liver Abscess, Amebic

1962
[ABSCESS OF THE LIVER AS A COMPLICATION OF AMEBIASIS].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1963, Jun-24, Volume: 18

    Topics: Abscess; Amebiasis; Chloroquine; Chlortetracycline; Clioquinol; Colitis; Colitis, Ulcerative; Congo; Dysentery, Amebic; Emetine; Humans; Iodoquinol; Liver Abscess; Liver Abscess, Amebic

1963
AMEBIASIS.
    The Journal of the Oklahoma State Medical Association, 1964, Volume: 57

    Topics: Amebiasis; Amebicides; Arsenicals; Biopsy; Chloroquine; Colitis; Colitis, Ulcerative; Diagnosis, Differential; Dysentery; Dysentery, Amebic; Emetine; Epidemiology; Feces; Humans; Liver Abscess; Liver Abscess, Amebic; Oklahoma; Sigmoidoscopy

1964
PARAGONIMIASIS IN EASTERN NIGERIA.
    The Journal of tropical medicine and hygiene, 1964, Volume: 67

    Topics: Child; Chloroquine; Diagnosis; Emetine; Epidemiology; Humans; Nigeria; Paragonimiasis

1964
[MYOSITIS AND PARACENTRAL SCOTOMA DUE TO EMETINE AND ARALEN THERAPIES].
    Harefuah, 1963, Sep-15, Volume: 65

    Topics: Chloroquine; Emetine; Myositis; Scotoma; Toxicology

1963
EXTRA-INTESTINAL AMEBIASIS: REPORT OF FOUR CASES.
    The Medical annals of the District of Columbia, 1964, Volume: 33

    Topics: Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Humans; Liver Abscess; Liver Abscess, Amebic; Lung Abscess; Lung Diseases, Parasitic

1964
[A CASE OF AMEBIASIS COMPLICATED BY LIVER ABSCESS].
    Biuletyn Instytutu Medycyny Morskiej w Gdansku, 1964, Volume: 15

    Topics: Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Humans; Liver Abscess; Liver Abscess, Amebic

1964
AMOEBIASIS PAST AND PRESENT.
    The Journal of tropical medicine and hygiene, 1964, Volume: 67

    Topics: Amebiasis; Amebicides; Child; Chloroquine; Dysentery; Dysentery, Amebic; Emetine; Epidemiology; Humans; India; Liver Abscess; Liver Abscess, Amebic; Lung Diseases; Lung Diseases, Parasitic; Surgical Procedures, Operative

1964
RIGHT MIDDLE LOBE ABSCESS DUE TO ENDAMOEBA HISTOLYTICA. REPORT OF TWO CASES.
    Diseases of the chest, 1964, Volume: 45

    Topics: Abscess; Amebiasis; Black People; Bronchography; Bronchoscopy; Chloroquine; Dysentery, Amebic; Emetine; Entamoeba histolytica; Humans; Iodoquinol; Liver Abscess; Liver Abscess, Amebic; Lung Abscess; Lung Diseases, Parasitic; Pathology; Penicillins; Pneumonectomy; Pneumoperitoneum; Pneumoperitoneum, Artificial; Streptomycin; Tetracycline

1964
CHEMOTHERAPY OF TROPICAL DISEASES.
    Current medicine and drugs, 1964, Volume: 4, Issue:10

    Topics: Amebiasis; Amebicides; Anti-Bacterial Agents; Antimalarials; Antimony; Arsenicals; Chagas Disease; Chloroquine; Dysentery, Amebic; Emetine; Humans; Iodoquinol; Leishmaniasis; Leishmaniasis, Mucocutaneous; Leishmaniasis, Visceral; Malaria; Suramin; Trypanosomiasis; Trypanosomiasis, African; United States

1964
[OBSERVATIONS ON HEPATIC ABSCESS IN TRUJILLO STATE AND A THEORY TO EXPLAIN ITS INCREASE].
    Revista venezolana de sanidad y asistencia social, 1963, Volume: 28

    Topics: Adolescent; Anti-Bacterial Agents; Child; Chloroquine; Diagnosis; Emetine; Geriatrics; Humans; Infant; Liver Abscess; Liver Abscess, Amebic; Mortality; Pathology; Protein Synthesis Inhibitors; Radiography; Statistics as Topic; Surgical Procedures, Operative; Tetracycline; Venezuela

1963
CHEMOTHERAPY OF CUTANEOUS LEISHMANIASIS: LEISHMANIA TROPICA INFECTIONS IN MICE.
    Annals of tropical medicine and parasitology, 1964, Volume: 58

    Topics: Amidines; Animals; Antimony; Antiprotozoal Agents; Chloroquine; Chlortetracycline; Dapsone; Deoxyribonuclease I; Emetine; Hyaluronoglucosaminidase; Hydrastis; Leishmania tropica; Leishmaniasis; Leishmaniasis, Cutaneous; Leishmaniasis, Mucocutaneous; Mice; Pathology; Pharmacology; Primaquine; Pyrimethamine; Quinacrine; Research; Streptodornase and Streptokinase; Streptokinase; Sulfonamides; Surface-Active Agents; Toxicology

1964
PLEUROPULMONARY AMEBIASIS. CLINICAL ANALYSIS OF 64 CASES.
    Chinese medical journal (Peking, China : 1932), 1965, Volume: 84

    Topics: Amebiasis; Chloroquine; Diagnosis, Differential; Drainage; Drug Therapy; Emetine; Empyema; Humans; Liver Abscess; Liver Abscess, Amebic; Lung Abscess; Lung Diseases, Parasitic; Pathology; Pleural Effusion; Pleurisy; Prognosis; Quinacrine; Radiography, Thoracic

1965
HEXACHLOROPARAXYLOL IN THE TREATMENT OF CLONORCHIASIS SINENSIS.
    Chinese medical journal (Peking, China : 1932), 1965, Volume: 84

    Topics: Anthelmintics; Cats; Chloroquine; Clonorchiasis; Drug Therapy; Emetine; Hexachlorophene; Pharmacology; Toxicology; Xylenes

1965
[COLLIQUATIVE AMEBIC HAPITITIS, WITH SECONDARY PULMONARY ABSCESS. ASSOCIATED CHLOROQUINE-EMETINE TREATMENT. RECOVERY].
    Acta medica Italica di medicina tropicale e subtropicale e di gastroenterologia, 1963, Volume: 18

    Topics: Abscess; Chloroquine; Emetine; Geriatrics; Liver Abscess; Liver Abscess, Amebic; Lung Abscess; Lung Neoplasms

1963
ELECTROCARDIOGRAM AFTER CHLOROQUINE AND EMETINE.
    Circulation, 1965, Volume: 32

    Topics: Blood Chemical Analysis; Chloroquine; Drug Therapy; Dysentery; Dysentery, Amebic; Electrocardiography; Emetine; Liver Abscess; Liver Abscess, Amebic; Potassium; Toxicology

1965
CIBA 32,644-BA, A NEW SYSTEMICALLY ACTIVE AMOEBICIDE.
    Annals of tropical medicine and parasitology, 1965, Volume: 59

    Topics: Amebicides; Chloroquine; Cricetinae; Dysentery; Dysentery, Amebic; Emetine; Guinea Pigs; Liver Abscess; Liver Abscess, Amebic; Niridazole; Pathology; Pharmacology; Phenanthrolines; Quinones; Rats; Research; Toxicology

1965
Treatment of amoebic hepatitis with emetine and chloroquine.
    Panminerva medica, 1959, Volume: 1

    Topics: Amebiasis; Chloroquine; Emetine; Hepatitis; Humans

1959
A comparison of chloroquine and emetine in the treatment of amoebic liver abscess.
    The Indian medical gazette, 1951, Volume: 86, Issue:4

    Topics: Amebiasis; Chloroquine; Dysentery, Amebic; Emetine; Liver Abscess, Amebic; Quinine

1951
Chemotherapy of amebic hepatitis in hamsters with emetine, chloroquine, amodiaquin (camoquin), quinacrine and other drugs.
    The American journal of tropical medicine and hygiene, 1951, Volume: 31, Issue:6

    Topics: Amebiasis; Amodiaquine; Chloroquine; Dysentery, Amebic; Emetine; Hepatitis; Liver Diseases; Quinacrine

1951
[Chloroquine therapy of liver abscess].
    Nederlands tijdschrift voor geneeskunde, 1951, Nov-10, Volume: 95, Issue:45

    Topics: Amebiasis; Chloroquine; Emetine; Liver Abscess; Liver Diseases

1951
Less commonly recognized clinical features of amebiasis.
    California medicine, 1952, Volume: 76, Issue:4

    Topics: Amebiasis; Arsanilic Acid; Chloroquine; Cholecystitis; Diarrhea; Dysentery, Amebic; Emetine; Humans; Iodoquinol; Liver Abscess, Amebic; Pleurisy

1952
Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Computational Biology; Drug Combinations; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Emetine; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil

2017
In Vitro Data of Current Therapies for SARS-CoV-2.
    Current medicinal chemistry, 2020, Volume: 27, Issue:27

    Topics: Adenosine Monophosphate; Alanine; Betacoronavirus; China; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Emetine; Homoharringtonine; Humans; Hydroxychloroquine; Ivermectin; Lopinavir; Nitro Compounds; Pandemics; Pneumonia, Viral; SARS-CoV-2; Teicoplanin; Thiazoles

2020
Emetine in Combination with Chloroquine Induces Oncolytic Potential of HIV-1-Based Lentiviral Particles.
    Cells, 2022, 09-10, Volume: 11, Issue:18

    Topics: Antiviral Agents; Chloroquine; Emetine; HIV-1; Humans

2022