chloroquine and eflornithine

chloroquine has been researched along with eflornithine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A1
Bitonti, AJ; Byers, TL; Cross-Doersen, DE; McCann, PP; Wright, PS1
Bitonti, AJ; Bush, TL; Dumont, JA; Edwards, ML; McCann, PP; Sjoerdsma, A; Stemerick, DM1
Bone, G; Charlier, J; Gillet, J; Lowa, P; Rona, AM; Schechter, PJ1
Königk, E; Putfarken, B2
Li, J; Liu, Y; Su, RB; Wei, XL1
Perišić, O1

Other Studies

11 other study(ies) available for chloroquine and eflornithine

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
    Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18

    Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids.
    Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

    Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2010
Irreversible inhibition of S-adenosylmethionine decarboxylase in Plasmodium falciparum-infected erythrocytes: growth inhibition in vitro.
    Biochemical pharmacology, 1991, Jun-01, Volume: 41, Issue:11

    Topics: Adenosylmethionine Decarboxylase; Animals; Cells, Cultured; Chloroquine; Deoxyadenosines; Eflornithine; Erythrocytes; Humans; Plasmodium falciparum; Polyamines; Spermidine; Spermine

1991
Bis(benzyl)polyamine analogs inhibit the growth of chloroquine-resistant human malaria parasites (Plasmodium falciparum) in vitro and in combination with alpha-difluoromethylornithine cure murine malaria.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:2

    Topics: Animals; Antimalarials; Chloroquine; DNA; Drug Resistance; Drug Therapy, Combination; Eflornithine; Humans; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Polyamines; Protein Biosynthesis; RNA

1989
alpha-Difluoromethylornithine induces protective immunity in mice inoculated with Plasmodium berghei sporozoites.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, Volume: 80, Issue:2

    Topics: Animals; Chloroquine; Eflornithine; Immunization; Malaria; Mice; Plasmodium berghei

1986
Ornithine decarboxylase of Plasmodium falciparum: a peak-function enzyme and its inhibition by chloroquine.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1985, Volume: 36, Issue:2

    Topics: Animals; Chloroquine; Drug Interactions; Eflornithine; Hydrogen-Ion Concentration; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plasmodium falciparum; Putrescine; Spermidine

1985
Inhibition of ornithine decarboxylase of in vitro cultured Plasmodium falciparum by chloroquine.
    Tropenmedizin und Parasitologie, 1983, Volume: 34, Issue:1

    Topics: Carboxy-Lyases; Chloroquine; Culture; DNA; Eflornithine; Humans; Mefloquine; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plasmodium falciparum; Quinolines

1983
Antimalarial effect of agmatine on Plasmodium berghei K173 strain.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:9

    Topics: Agmatine; Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Resistance; Eflornithine; Female; Malaria; Male; Mice; Ornithine Decarboxylase Inhibitors; Parasitemia; Parasitic Sensitivity Tests; Plasmodium berghei

2003
Recognition of Potential COVID-19 Drug Treatments through the Study of Existing Protein-Drug and Protein-Protein Structures: An Analysis of Kinetically Active Residues.
    Biomolecules, 2020, 09-21, Volume: 10, Issue:9

    Topics: Adenosine Monophosphate; Alanine; Angiotensin-Converting Enzyme 2; Antibodies, Viral; Antigen-Antibody Reactions; Antiviral Agents; Betacoronavirus; Binding Sites; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Eflornithine; Humans; Hydrophobic and Hydrophilic Interactions; Ivermectin; L-Lactate Dehydrogenase; Models, Molecular; Molecular Docking Simulation; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Proline; Protein Binding; Protein Conformation; Protein Interaction Mapping; Receptors, Glycine; Saposins; SARS-CoV-2; Sofosbuvir; Spike Glycoprotein, Coronavirus; Structure-Activity Relationship

2020