Compounds > chloroquine

chloroquine and desethylamodiaquine

chloroquine has been researched along with desethylamodiaquine in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.90)18.7374
1990's6 (14.29)18.2507
2000's13 (30.95)29.6817
2010's17 (40.48)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Bray, PG; Hawley, SR; O'Neill, PM; Park, BK; Storr, RC; Ward, SA; Willock, DJ1
Bambal, RB; Bates, M; Berry, N; Biagini, GA; Bonar-Law, R; Bray, PG; Brigandi, RA; Davis, CB; Gargallo, DV; Gibbons, P; Gomez-delas-Heras, FM; Gresham, SL; Hart, TK; Hindley, S; Lawrence, RM; Maggs, JL; Mukhtar, A; O'Neill, PM; Park, BK; Roberts, P; Shone, AE; Stocks, PA; Ward, SA; Winstanley, PA1
Asadollahy, E; Bambal, RB; Bates, M; Berry, N; Biagini, G; Bray, PG; Brigandi, RA; Davies, J; Davis, CB; Gargallo, DV; Gomez-de-Las-Heras, FM; Gresham, SL; Hall, C; Hindley, S; Lander, H; Maggs, JL; Nixon, G; O'Neill, PM; Parapini, S; Park, BK; Rimmer, K; Roberts, P; Shone, AE; Stanford, D; Stocks, PA; Taramelli, D; Vivas, L; Ward, SA; Winstanley, PA1
Almeras, L; Amalvict, R; Baret, E; Briolant, S; Fusaï, T; Henry, M; Parquet, V; Pradines, B; Rogier, C; Torrentino-Madamet, M1
Masseno, V; Muriithi, S; Nzila, A1
Andrianaranjaka, V; Andriantsoanirina, V; Bouchier, C; Durand, R; Jahevitra, M; Ménard, D; Mercereau-Puijalon, O; Rabarijaona, LP; Rabearimanana, S; Radrianjafy, R; Randriantsoa, T; Rason, MA; Ratsimbasoa, A; Tichit, M1
Greenhouse, B; Joloba, M; Kiggundu, M; Nanyunja, S; Nsobya, SL; Rosenthal, PJ1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Biot, C; Brun, R; Chavain, N; Davioud-Charvet, E; Friebolin, W; Herold-Mende, C; Lanzer, M; Maes, L; Pradines, B; Tóth, K; Wang, Y; Wenzel, NI; Yardley, V1
Amalvict, R; Baret, E; Briolant, S; Didillon, E; Henry, M; Oeuvray, C; Pradines, B; Rogier, C1
Gut, J; Kumar, V; Raj, R; Rosenthal, PJ; Singh, P1
Agnamey, P; Azas, N; Cohen, A; Damiani, C; Dassonville-Klimpt, A; Dormoi, J; Guillon, J; Marchivie, M; Mullié, C; Pradines, B; Schneider, J; Sonnet, P; Taudon, N; Tisnerat, C; Totet, A1
Basco, LK; Le Bras, J2
Basco, LK2
Breckenridge, AM; Coleman, JW; Maggs, JL; Park, BK; Winstanley, PA1
Boudreau, EF; Childs, GE; Davidson, DE; Milhous, WK; Pang, L; Pooyindee, N; Wimonwattratee, T1
Drouville, C; Guigon, D; Le Bras, J; Porte, J; Simon, F; Verdier, F1
Biaud, JM; Calmel, MB; Clausse, JL; Deloron, P; Hatin, I; Le Bras, J; Marchais, H; Porte, J; Ramanamirija, JA; Simon, F1
Coulanges, P; Le Bras, J; Marchais, H; Ramanamirija, JA1
Breckenridge, A; Edwards, G; Orme, M; Winstanley, P1
Baba, H; Campistron, G; Chretien, P; Coulais, Y; Laurent, F; Magnaval, JF; Peyron, F; Saivin, S; Sqalli, A; Tufenkji, AE1
Warhurst, DC1
D'Alessandro, U; Erhart, A; Karema, C; Mupfasoni, D; Rusanganwa, E; Rwagacondo, C; Tinto, H; Van Marck, E; Van Overmeir, C; Vandoren, W1
Bell, DJ; Molyneux, ME; Nyirongo, SK; Ward, SA; Winstanley, PA1
Andrianantenaina, HB; Ariey, F; Domarle, O; Randrianarivelojosia, M; Rason, MA; Raveloson, A1
Stepniewska, K; White, NJ1
Arango, E; Cravo, P; Do Rosário, VE; Maestre, A; Restrepo-Pineda, E1
Amalvict, R; Baret, E; Briolant, S; Fontaine, A; Fraisse, L; Fusaï, T; Henry, M; Mosnier, J; Pradines, B; Rogier, C1
Almeras, L; Amalvict, R; Baret, E; Briolant, S; Gil, M; Henry, M; Parquet, V; Pradines, B; Rogier, C; Wurtz, N1
Blair, S; Deharo, E; Pabón, A1
Amalvict, R; Baret, E; Briolant, S; Charras, S; Feraud, M; Henry, M; Huyghues des Etages, E; Pascual, A; Pradines, B; Rogier, C1
Anvikar, AR; Bhatt, RM; Dash, AP; Ghosh, SK; Kumar, A; Mohanty, SS; Pillai, CR; Sharma, B; Sharma, SK; Valecha, N1
Ali, A; Björkman, A; Ferreira, PE; Fröberg, G; Gil, JP; Mårtensson, A1
Cooksey, R; Dahlström, S; Fairhurst, RM; Flegg, JA; Guerin, PJ; Johnson, JD; Le Bras, J; Le Nagard, H; Lim, P; Ménard, D; Mentré, F; Murillo, C; Musset, L; Noedl, H; Nosten, F; Nsobya, SL; Pradines, B; Quashie, NB; Sibley, CH; Sinou, V; Sriprawat, K; Woodrow, CJ1
Baret, E; Bercion, R; Camara, C; Diatta, B; Diémé, Y; Fall, B; Fall, KB; Fall, M; Mbaye, PS; Nakoulima, A; Pascual, A; Pradines, B; Wade, B; Wurtz, N1
Bigira, V; Bloome, J; Byaruhanga, O; Conrad, MD; Cooper, RA; Dorsey, G; Greenhouse, B; Gut, J; Havlir, DV; Kakuru, A; Kamya, MR; Kapisi, J; Kozak, B; LeClair, N; Legac, J; Nakazibwe, C; Nsobya, SL; Okiring, J; Rosenthal, PJ; Tumwebaze, P; Walakira, A1
Craig, JC; Raheem, KS; Warhurst, DC1
Amalvict, R; Benoit, N; Briolant, S; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Kounta, MB; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA1
Amalvict, R; Bercion, R; Diatta, B; Diawara, S; Fall, B; Gueye, MW; Kounta, MB; Lo, G; Madamet, M; Nakoulima, A; Pradines, B; Wade, KA1
Byaruhanga, O; Ceja, FG; Conrad, MD; Cooper, RA; Katairo, T; Nsobya, SL; Rasmussen, SA; Rosenthal, PJ; Tumwebaze, PK1

Trials

2 trial(s) available for chloroquine and desethylamodiaquine

ArticleYear
In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Antimalarials; Child; Child, Preschool; Cohort Studies; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Treatment Outcome; Uganda

2010
Changing Antimalarial Drug Sensitivities in Uganda.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12

    Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Child; Child, Preschool; Chloroquine; Drug Resistance; Ethanolamines; Female; Fluorenes; Gene Expression; Humans; Infant; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinolines; Uganda; Young Adult

2017

Other Studies

40 other study(ies) available for chloroquine and desethylamodiaquine

ArticleYear
Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues.
    Journal of medicinal chemistry, 1997, Feb-14, Volume: 40, Issue:4

    Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Heme; Humans; Models, Molecular; Plasmodium falciparum

1997
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
    Journal of medicinal chemistry, 2009, Mar-12, Volume: 52, Issue:5

    Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Benzylamines; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Female; Haplorhini; Heme; Humans; Malaria; Mice; Models, Molecular; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Structure-Activity Relationship

2009
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
    Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7

    Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Cell Survival; Chloroquine; Dogs; Drug Resistance; Female; Haplorhini; Hepatocytes; Humans; In Vitro Techniques; Malaria; Male; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Rats, Wistar; Structure-Activity Relationship

2009
Atorvastatin is a promising partner for antimalarial drugs in treatment of Plasmodium falciparum malaria.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Animals; Antimalarials; Atorvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Plasmodium falciparum; Pyrroles

2009
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil

2009
Plasmodium falciparum drug resistance in Madagascar: facing the spread of unusual pfdhfr and pfmdr-1 haplotypes and the decrease of dihydroartemisinin susceptibility.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Haplotypes; Madagascar; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Aminoquinolines; Antimalarials; Antineoplastic Agents; Cell Line, Tumor; DNA; Drug Resistance; Drug Screening Assays, Antitumor; Hemeproteins; Humans; Mannich Bases; Plasmodium falciparum; Structure-Activity Relationship

2010
Absence of association between piperaquine in vitro responses and polymorphisms in the pfcrt, pfmdr1, pfmrp, and pfnhe genes in Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Animals; Antimalarials; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines

2010
Urea/oxalamide tethered β-lactam-7-chloroquinoline conjugates: synthesis and in vitro antimalarial evaluation.
    European journal of medicinal chemistry, 2014, Volume: 71

    Topics: Antimalarials; beta-Lactams; Chloroquine; Humans; Malaria, Falciparum; Oxamic Acid; Plasmodium falciparum; Structure-Activity Relationship; Urea

2014
Design, synthesis, and characterization of novel aminoalcohol quinolines with strong in vitro antimalarial activity.
    European journal of medicinal chemistry, 2022, Jan-15, Volume: 228

    Topics: Amino Alcohols; Animals; Antimalarials; Cell Line; Cricetulus; Dose-Response Relationship, Drug; Drug Design; Ether-A-Go-Go Potassium Channels; Female; Humans; Malaria; Mice; Mice, Inbred BALB C; Microsomes, Liver; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship

2022
In vitro activity of pyronaridine against African strains of Plasmodium falciparum.
    Annals of tropical medicine and parasitology, 1992, Volume: 86, Issue:5

    Topics: Africa; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Naphthyridines; Plasmodium falciparum

1992
Inefficacy of amodiaquine against chloroquine-resistant malaria.
    Lancet (London, England), 1991, Dec-07, Volume: 338, Issue:8780

    Topics: Amodiaquine; Animals; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Plasmodium falciparum

1991
The toxicity of amodiaquine and its principal metabolites towards mononuclear leucocytes and granulocyte/monocyte colony forming units.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:4

    Topics: Amodiaquine; Bone Marrow; Bone Marrow Cells; Cell Survival; Chloroquine; Colony-Forming Units Assay; Granulocytes; Humans; In Vitro Techniques; Leukocytes, Mononuclear

1990
A comparison of the in vitro activities of amodiaquine and desethylamodiaquine against isolates of Plasmodium falciparum.
    The American journal of tropical medicine and hygiene, 1989, Volume: 40, Issue:1

    Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinolines; Thailand

1989
[Drug sensitivity of malaria in a population of children in Pointe-Noire, Congo, in the first half of 1986].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1987, Volume: 80, Issue:3 Pt 2

    Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Congo; Drug Resistance; Humans; Infant; Malaria; Plasmodium falciparum

1987
[Sensitivity of Plasmodium falciparum to quinolines and therapeutic strategies: comparison of the situation in Africa and Madagascar between 1983 and 1986].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1987, Volume: 80, Issue:3 Pt 2

    Topics: Amodiaquine; Angola; Animals; Antimalarials; Burkina Faso; Cameroon; Chloroquine; Drug Resistance; Humans; Madagascar; Malaria; Mefloquine; Plasmodium falciparum; Quinine; Quinolines

1987
[In vivo and in vitro sensitivity to 4-aminoquinolines of Plasmodium falciparum in Madagascar: results of a study conducted on the east coast (July 1985-July 1986)].
    Archives de l'Institut Pasteur de Madagascar, 1987, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Aminoquinolines; Amodiaquine; Animals; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Infant; Madagascar; Malaria; Plasmodium falciparum

1987
The disposition of amodiaquine in man after oral administration.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:1

    Topics: Administration, Oral; Adult; Amodiaquine; Chloroquine; Erythrocytes; Humans; Kinetics; Male; Mass Spectrometry

1987
Pharmacokinetic and pharmacodynamic study of amodiaquine and its two metabolites after a single oral dose in human volunteers.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:5

    Topics: Adult; Amodiaquine; Animals; Chloroquine; Diffusion Chambers, Culture; Erythrocytes; Half-Life; Humans; Leukocytes; Male; Plasmodium falciparum; Spectrophotometry, Ultraviolet

1993
In vitro activity of monodesethylamodiaquine and amopyroquine against African isolates and clones of Plasmodium falciparum.
    The American journal of tropical medicine and hygiene, 1993, Volume: 48, Issue:1

    Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Plasmodium falciparum; Regression Analysis

1993
Molecular epidemiology of malaria in Cameroon. XV. Experimental studies on serum substitutes and supplements and alternative culture media for in vitro drug sensitivity assays using fresh isolates of Plasmodium falciparum.
    The American journal of tropical medicine and hygiene, 2003, Volume: 69, Issue:2

    Topics: Amodiaquine; Animals; Antimalarials; Cameroon; Chloroquine; Culture Media; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Serum Albumin

2003
Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine.
    Malaria journal, 2003, Sep-19, Volume: 2

    Topics: Amodiaquine; Animals; Antimalarials; Cell Line; Chloride Channels; Chloroquine; Drug Resistance; Drug Synergism; Hydrophobic and Hydrophilic Interactions; Ion Channels; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Transfection; Verapamil

2003
In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Multiple; Female; Humans; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Rwanda; Sesquiterpenes

2006
Practical HPLC methods for the quantitative determination of common antimalarials in Africa.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Mar-01, Volume: 847, Issue:2

    Topics: Africa; Amodiaquine; Antimalarials; Chloroquine; Chromatography, High Pressure Liquid; Humans; Pyrimethamine; Reproducibility of Results; Sulfadoxine

2007
Prevalent pfmdr1 n86y mutant Plasmodium falciparum in Madagascar despite absence of pfcrt mutant strains.
    The American journal of tropical medicine and hygiene, 2007, Volume: 76, Issue:6

    Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; DNA, Protozoan; Drug Resistance; Humans; Inhibitory Concentration 50; Madagascar; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Protozoan Proteins; Quinine; Rural Population

2007
Pharmacokinetic determinants of the window of selection for antimalarial drug resistance.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Algorithms; Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Computer Simulation; Drug Resistance; Malaria; Mefloquine; Models, Theoretical; Pyrimethamine; Quinine

2008
Studies on antimalarial drug susceptibility in Colombia, in relation to Pfmdr1 and Pfcrt.
    Parasitology, 2008, Volume: 135, Issue:5

    Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Colombia; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Protozoan Proteins

2008
In vitro activity of ferroquine is independent of polymorphisms in transport protein genes implicated in quinoline resistance in Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Aminoquinolines; Amodiaquine; Animals; Chloroquine; Drug Resistance, Bacterial; Ferrous Compounds; Mefloquine; Membrane Transport Proteins; Metallocenes; Microsatellite Repeats; Molecular Structure; Plasmodium falciparum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines

2008
Synergy of mefloquine activity with atorvastatin, but not chloroquine and monodesethylamodiaquine, and association with the pfmdr1 gene.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:7

    Topics: Amodiaquine; Antimalarials; Atorvastatin; Chloroquine; DNA, Protozoan; Drug Synergism; Gene Dosage; Genotype; Heptanoic Acids; Humans; Inhibitory Concentration 50; Mefloquine; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrroles

2010
Plasmodium falciparum: Solanum nudum SN-1 steroid antiplasmodial activity when combined with antimalarial drugs.
    Experimental parasitology, 2011, Volume: 127, Issue:1

    Topics: Amodiaquine; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Synergism; Erythrocytes; Flow Cytometry; Humans; Phytosterols; Plasmodium falciparum; Quinine; Solanum; Trophozoites

2011
In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5

    Topics: Amodiaquine; Antimalarials; Chloroquine; Ethanolamines; Fluorenes; Inhibitory Concentration 50; Lumefantrine; Mefloquine; Methylene Blue; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine

2011
In vitro assessment of drug resistance in Plasmodium falciparum in five States of India.
    The Indian journal of medical research, 2012, Volume: 135, Issue:4

    Topics: Amodiaquine; Artemisinins; Artesunate; Biomarkers, Pharmacological; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; India; Mefloquine; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins

2012
Assessing the cost-benefit effect of a Plasmodium falciparum drug resistance mutation on parasite growth in vitro.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Amodiaquine; Antimalarials; Biological Transport; Chloroquine; Drug Resistance; Genetic Fitness; Genotype; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum

2013
High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Amodiaquine; Antimalarials; Artemisinins; Automation, Laboratory; Chloroquine; Drug Resistance; Drug Therapy, Combination; High-Throughput Screening Assays; Internet; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine

2013
Role of Pfmdr1 in in vitro Plasmodium falciparum susceptibility to chloroquine, quinine, monodesethylamodiaquine, mefloquine, lumefantrine, and dihydroartemisinin.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12

    Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Biological Transport; Child; Chloroquine; Drug Resistance; Erythrocytes; Ethanolamines; Female; Fluorenes; Gene Expression; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinine; Senegal

2014
Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6

    Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Clinical Trials as Topic; Ethanolamines; Fluorenes; Humans; Infant; Lumefantrine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Quinolines; Uganda

2015
Influence of LAR and VAR on Para-Aminopyridine Antimalarials Targetting Haematin in Chloroquine-Resistance.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Amodiaquine; Antimalarials; Biological Transport; Chloroquine; Drug Design; Drug Resistance; Heme; Hemin; Hydrophobic and Hydrophilic Interactions; Plasmodium falciparum; Quinolines; Structure-Activity Relationship; Vacuoles

2016
Association between Polymorphisms in the Pf
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:3

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal

2017
Confirmation of Plasmodium falciparum in vitro resistance to monodesethylamodiaquine and chloroquine in Dakar, Senegal, in 2015.
    Malaria journal, 2017, 03-16, Volume: 16, Issue:1

    Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Plasmodium falciparum; Senegal

2017