chloroquine and deoxycytidine

chloroquine has been researched along with deoxycytidine in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	7 (63.64)	24.3611
2020's	4 (36.36)	2.80

Authors

Authors	Studies
Jenks, S	1
Bläuer, M; Hashimoto, D; Hirota, M; Ikonen, NH; Laukkarinen, J; Sand, J	1
Chen, L; Chen, M; Dai, F; He, M; Shen, P; Song, Y; Wan, X; Xiao, P	1
Bachmann, H; Knuth, A; Nguyen-Kim, TDL; Pascolo, S; Samaras, P; Seifert, B; Tusup, M; von Moos, R	1
Chen, L; Cheng, X; Feng, H; Fu, Z; Jin, Z; Kuang, J; Liang, J; Peng, C; Qiu, W; Shen, B; Shen, X; Yuen, S	1
Ji, Z; Xu, C; Xu, R; Zhu, J	1
Abdel Karim, N; Aljohani, HM; Bahassi, EM; Eldessouki, I; Gaber, O; Morris, J	1
Deng, CL; Li, XD; Wang, Z; Wei, HP; Xiao, SQ; Xiong, J; Yang, XL; Ye, HQ; Yuan, ZM; Zhang, B; Zhang, QY; Zhang, YN; Zhang, ZR	1
Fan, YZ; Li, XP; Pan, MS; Sun, W; Wang, FT; Wang, H; Wang, QW	1
Curiel, TJ; Deng, Y; Gupta, HB; Kancharla, A; Kari, S; Kornepati, AVR; Li, R; Osta, E; Padron, AS; Reyes, RM; Sun, X; Svatek, RS; Vadlamudi, R; Wu, B; Zhang, D	1
Dai, C; Gong, T; Guo, Y; Huang, Y; Pan, H; Wu, D; Yan, J; Yang, Y; Zhao, Y; Zhu, S	1

Reviews

1 review(s) available for chloroquine and deoxycytidine

Article	Year
The clinical value of using chloroquine or hydroxychloroquine as autophagy inhibitors in the treatment of cancers: A systematic review and meta-analysis. Medicine, 2018, Volume: 97, Issue:46 Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy; Chloroquine; Clinical Trials as Topic; Dacarbazine; Deoxycytidine; Doxorubicin; Gemcitabine; Humans; Hydroxychloroquine; Neoplasms; Risk; Temozolomide; Treatment Outcome	2018

Article

Year

The clinical value of using chloroquine or hydroxychloroquine as autophagy inhibitors in the treatment of cancers: A systematic review and meta-analysis.

Medicine, 2018, Volume: 97, Issue:46

Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy; Chloroquine; Clinical Trials as Topic; Dacarbazine; Deoxycytidine; Doxorubicin; Gemcitabine; Humans; Hydroxychloroquine; Neoplasms; Risk; Temozolomide; Treatment Outcome

2018

Trials

1 trial(s) available for chloroquine and deoxycytidine

Article	Year
Phase I study of a chloroquine-gemcitabine combination in patients with metastatic or unresectable pancreatic cancer. Cancer chemotherapy and pharmacology, 2017, Volume: 80, Issue:5 Topics: Aged; Antimalarials; Antimetabolites, Antineoplastic; Chloroquine; Deoxycytidine; Female; Gemcitabine; Humans; Male; Pancreatic Neoplasms	2017

Other Studies

9 other study(ies) available for chloroquine and deoxycytidine

Article	Year
AACR highlights: promise for treating pancreatic cancer. Journal of the National Cancer Institute, 2011, May-18, Volume: 103, Issue:10 Topics: Albumin-Bound Paclitaxel; Albumins; Anilides; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Chloroquine; Clinical Trials as Topic; Delayed Diagnosis; Deoxycytidine; Disease Progression; Gemcitabine; Genes, ras; Humans; Mice; Molecular Targeted Therapy; Mutation; Off-Label Use; Paclitaxel; Pancreatic Neoplasms; Pyridines; Signal Transduction; Transcription Factors; United States	2011
Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs. European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:7 Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Cell Proliferation; Chloroquine; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Microtubule-Associated Proteins; Pancreatic Neoplasms; Protein Kinase Inhibitors; Wortmannin	2014
The cytoprotective role of gemcitabine-induced autophagy associated with apoptosis inhibition in triple-negative MDA-MB-231 breast cancer cells. International journal of molecular medicine, 2014, Volume: 34, Issue:1 Topics: Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Cell Line, Tumor; Chloroquine; Deoxycytidine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mammary Glands, Human; Proto-Oncogene Proteins c-bcl-2; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53	2014
CQ sensitizes human pancreatic cancer cells to gemcitabine through the lysosomal apoptotic pathway via reactive oxygen species. Molecular oncology, 2018, Volume: 12, Issue:4 Topics: Animals; Apoptosis; Cell Line, Tumor; Chloroquine; Deoxycytidine; Gemcitabine; Humans; Lysosomes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Pancreatic Neoplasms; Reactive Oxygen Species; Xenograft Model Antitumor Assays	2018
Exosomes as a Surrogate Marker for Autophagy in Peripheral Blood, Correlative Data from Phase I Study of Chloroquine in Combination with Carboplatin/Gemcitabine in Advanced Solid Tumors. Asian Pacific journal of cancer prevention : APJCP, 2019, 12-01, Volume: 20, Issue:12 Topics: Antimalarials; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Biomarkers; Carboplatin; Chloroquine; Deoxycytidine; Drug Therapy, Combination; Exosomes; Gemcitabine; Humans; Neoplasms; Tumor Cells, Cultured	2019
Gemcitabine, lycorine and oxysophoridine inhibit novel coronavirus (SARS-CoV-2) in cell culture. Emerging microbes & infections, 2020, Volume: 9, Issue:1 Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antiviral Agents; Betacoronavirus; Cell Survival; Chlorocebus aethiops; Chloroquine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Gemcitabine; Phenanthridines; SARS-CoV-2; Vero Cells; Virus Replication	2020
Inhibition of autophagy by chloroquine enhances the antitumor activity of gemcitabine for gallbladder cancer. Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:2 Topics: Animals; Antimalarials; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Cell Proliferation; Chloroquine; Deoxycytidine; Drug Synergism; Drug Therapy, Combination; Gallbladder Neoplasms; Gemcitabine; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2020
Bladder cancer cell-intrinsic PD-L1 signals promote mTOR and autophagy activation that can be inhibited to improve cytotoxic chemotherapy. Cancer medicine, 2021, Volume: 10, Issue:6 Topics: Animals; Antibiotics, Antineoplastic; Autophagy; B7-H1 Antigen; Cell Line, Tumor; Cell Proliferation; Chloroquine; Cisplatin; Deoxycytidine; Drug Resistance, Neoplasm; Female; Gemcitabine; Gene Expression; Humans; Mechanistic Target of Rapamycin Complex 1; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; Ovarian Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Sirolimus; Urinary Bladder Neoplasms	2021
Matrix stiffness triggers chemoresistance through elevated autophagy in pancreatic ductal adenocarcinoma. Biomaterials science, 2023, Nov-07, Volume: 11, Issue:22 Topics: Autophagy; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Chloroquine; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Pancreatic Neoplasms	2023