chloroquine has been researched along with dactolisib in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Cheng, C; Debnath, J; Fan, QW; Feldman, M; Haas-Kogan, D; Hackett, C; Houseman, BT; James, CD; Nicolaides, T; Oakes, SA; Shokat, KM; Weiss, WA | 1 |
| Fang, G; Khuri, FR; Owonikoko, TK; Ramalingam, SS; Sun, SY; Tao, H; Xu, CX; Yue, P; Zhao, L | 1 |
| Jin, X; Kong, X; Li, H; Xing, Y; Zhang, Z | 1 |
| Cristofanon, S; Fulda, S; Hugle, M; Seitz, C; Tchoghandjian, A | 1 |
| Fulda, S; Hugle, M | 1 |
| Cai, W; Di, W; Ji, Y; Lu, Z; Wu, J; Yang, Q | 1 |
| Avniel-Polak, S; Glaser, B; Gross, DJ; Grozinsky-Glasberg, S; Leibowitz, G; Riahi, Y | 1 |
8 other study(ies) available for chloroquine and dactolisib
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Akt and autophagy cooperate to promote survival of drug-resistant glioma.
Topics: Animals; Autophagy; Cell Line, Tumor; Chloroquine; Drug Synergism; Flow Cytometry; Furans; Glioma; Histological Techniques; Humans; Imidazoles; Immunoblotting; Immunohistochemistry; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Mitochondria; Mutation; Oncogene Protein v-akt; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Pyridines; Pyrimidines; Quinolines; Sirolimus; TOR Serine-Threonine Kinases; Transplantation, Heterologous | 2010 |
Augmentation of NVP-BEZ235's anticancer activity against human lung cancer cells by blockage of autophagy.
Topics: Animals; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chloroquine; Drug Synergism; Female; Humans; Imidazoles; Lung Neoplasms; Mice; Mice, Nude; Proto-Oncogene Proteins c-akt; Quinolines; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Burden; Xenograft Model Antitumor Assays | 2011 |
Inhibition of autophagy enhances apoptosis induced by the PI3K/AKT/mTor inhibitor NVP-BEZ235 in renal cell carcinoma cells.
Topics: Adenine; Apoptosis; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; Chloroquine; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Kidney Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases | 2013 |
The dual PI3K/mTOR inhibitor NVP-BEZ235 and chloroquine synergize to trigger apoptosis via mitochondrial-lysosomal cross-talk.
Topics: Antimalarials; Apoptosis; Autophagy; bcl-2-Associated X Protein; Blotting, Western; Cell Membrane Permeability; Chloroquine; Drug Synergism; Enzyme Inhibitors; Humans; Imidazoles; Immunoprecipitation; Lysosomes; Membrane Potential, Mitochondrial; Mitochondria; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2013 |
Dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 synergizes with chloroquine to induce apoptosis in embryonal rhabdomyosarcoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cell Line, Tumor; Chloroquine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Humans; Imidazoles; Lysosomes; Molecular Targeted Therapy; Mutation; Myeloid Cell Leukemia Sequence 1 Protein; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinolines; Reactive Oxygen Species; Rhabdomyosarcoma, Embryonal; Signal Transduction; TOR Serine-Threonine Kinases; Transfection | 2015 |
Inhibition of Autophagy Increases Proliferation Inhibition and Apoptosis Induced by the PI3K/mTOR Inhibitor NVP-BEZ235 in Breast Cancer Cells.
Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Autophagy-Related Protein 7; Breast Neoplasms; Cell Proliferation; Cell Survival; Chloroquine; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; MCF-7 Cells; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Transfection; Ubiquitin-Activating Enzymes | 2015 |
Abrogation of Autophagy by Chloroquine Alone or in Combination with mTOR Inhibitors Induces Apoptosis in Neuroendocrine Tumor Cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Everolimus; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Ki-67 Antigen; Microtubule-Associated Proteins; Neuroendocrine Tumors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Time Factors; TOR Serine-Threonine Kinases | 2016 |