chloroquine and cyclosporine

chloroquine has been researched along with cyclosporine in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	19 (36.54)	18.2507
2000's	16 (30.77)	29.6817
2010's	13 (25.00)	24.3611
2020's	4 (7.69)	2.80

Authors

Authors	Studies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Avery, VM; Sykes, ML	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Byun, SY; Choi, I; Jeon, S; Kim, S; Ko, M; Lee, J; Park, S; Shum, D	1
Flores, A; Little, GH	1
Breedveld, FC; Daha, MR; Dijkmans, BA; Landewé, RB; Miltenburg, AM	1
Gupta, RK; Johny, KV; Nampoory, MR; Nessim, J	1
Demidem, A; Grammer, SF; Streilein, JW; Taylor, JR	1
Gergely, P	1
Breedveld, FC; Daha, MR; Dijkmans, BA; Landewé, RB; Miltenburg, AM; Verdonk, MJ; Verweij, CL	1
Chong, AS; Coon, JS; Gebel, HM; Markham, PN	1
Breedveld, FC; Dijkmans, BA; Goei Thè, HS; Landewé, RB; van Rijthoven, AW	1
Chuet, C; Finielz, P; Gendoo, Z; Guiserix, J	1
Goos, M; Mertins, K; Nussbaum, G; Ockenfels, HM; Schultewolter, T; Wagner, SN	1
Hatta, N; Imai, T; Sakai, H; Takata, M; Takehara, K; Tsutsui, K	1
Breedveld, FC; Dijkmans, BA; Landewe, RB; Miltenburg, AM; van den Borne, BE; Verweij, CL	1
Bader, S; Nelson, D; Schultz, KR	1
Breedveld, FC; Dijkmans, BA; Landewé, RB; The, HS; van den Borne, BE	1
Aizel, A; Guiserix, J	1
Gilman, AL; Schultz, KR	1
Bader, S; HayGlass, KT; Nelson, D; Schultz, KR; Wang, MD	1
Menninger, H	1
Breedveld, FC; Bruyn, GA; Dijkmans, BA; Goei The, HS; Landewé, RB; Rietveld, JH; van den Borne, BE; Zwinderman, AH	1
Baldwin, W; Chen, W; Hess, AD; Hruban, R; Miura, Y; Qian, Z; Sommer, M; Thoburn, CJ	1
Di Poi, E; Fabris, M; Ferraccioli, G; Mecchia, F	1
Konishi, M; Takahashi, K; Yoneda, K; Yoshimoto, E	1
Gross, WL; Schnabel, A	1
Lasserson, T; Paramothayan, S; Walters, EH	1
Lasserson, TJ; Paramothayan, S; Walters, EH	1
Wieczorek, D	1
Tłustochowicz, W	1
Gergely, P; Poór, G	1
Assaraf, YG; Kaplan, A; Kreiserman, R; Stark, M; Yunaev, A; Zhitomirsky, B	1
Jamali, Z; Pirhadi, R; Pourahmad, J; Ramazani, M; Salimi, A; Yousefsani, BS	1
Amiri, N; Baldwin, C; De Vera, MA; Rebić, N; Sayre, EC; Zusman, EZ	1
Brun, P; Dubois, J; Dulière, V; Julien, T; Lina, B; Padey, B; Pizzorno, A; Rosa-Calatrava, M; Terrier, O; Traversier, A	1
Bennett, C; Chen, S; Hannon, CW; Lima, HC; McCourt, C	1

Reviews

11 review(s) available for chloroquine and cyclosporine

Article	Year
Approaches to protozoan drug discovery: phenotypic screening. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2013
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Chloroquine combined with cyclosporine in rheumatoid arthritis: more than the addition of 2 drugs alone. The Journal of rheumatology. Supplement, 1996, Volume: 44 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cyclosporine; Drug Synergism; Drug Therapy, Combination; Humans	1996
The lysosomotropic amines, chloroquine and hydroxychloroquine: a potentially novel therapy for graft-versus-host disease. Leukemia & lymphoma, 1997, Volume: 24, Issue:3-4 Topics: Animals; Antigen Presentation; Bone Marrow Transplantation; Chloroquine; Clinical Trials as Topic; Cyclosporine; Drug Synergism; Graft vs Host Disease; H-2 Antigens; Histocompatibility Antigens Class II; HLA Antigens; Humans; Hydroxychloroquine; Immunosuppressive Agents; Isoantigens; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; T-Lymphocytes, Cytotoxic	1997
[Basic therapeutic combination therapy in chronic polyarthritis: an overview]. Zeitschrift fur Rheumatologie, 1998, Volume: 57, Issue:1 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Clinical Trials as Topic; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Methotrexate; Treatment Outcome	1998
[Non-steroid therapy for sarcoidosis]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:9 Topics: Anti-Inflammatory Agents; Antimalarials; Azathioprine; Chlorambucil; Chloroquine; Cyclophosphamide; Cyclosporine; Humans; Methotrexate; Sarcoidosis; Steroids	2002
Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis. The Cochrane database of systematic reviews, 2003, Issue:3 Topics: Antineoplastic Agents; Chloroquine; Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Randomized Controlled Trials as Topic; Sarcoidosis, Pulmonary	2003
Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis. The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3 Topics: Antineoplastic Agents; Chloroquine; Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Pentoxifylline; Prednisone; Randomized Controlled Trials as Topic; Sarcoidosis, Pulmonary	2006
[Rational therapeutic approach in rheumatoid arthritis]. Annales Academiae Medicae Stetinensis, 2006, Volume: 52 Suppl 2 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Isoxazoles; Joint Prosthesis; Leflunomide; Methotrexate; Prostheses and Implants; Sulfasalazine	2006
[New ways in the management of rheumatoid arthritis in Hungary]. Lege artis medicinae : uj magyar orvosi hirmondo, 2007, Volume: 17, Issue:10 Topics: Abatacept; Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Rheumatoid; Autoimmunity; Azathioprine; Chloroquine; Cyclophosphamide; Cyclosporine; Diagnosis, Differential; Early Diagnosis; Etanercept; Humans; Hungary; Immunoconjugates; Immunoglobulin G; Immunologic Factors; Immunosuppressive Agents; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Prognosis; Receptors, Tumor Necrosis Factor; Rituximab; Sulfasalazine; Tumor Necrosis Factor-alpha	2007
Interventions for cutaneous disease in systemic lupus erythematosus. The Cochrane database of systematic reviews, 2021, 03-09, Volume: 3 Topics: Age of Onset; Azathioprine; Bias; Biological Factors; Chloroquine; Cosmetic Techniques; Cyclosporine; Dermatologic Agents; Exanthema; Female; Humans; Hydroxychloroquine; Immunosuppressive Agents; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Male; Medicine, Chinese Traditional; Methotrexate; Placebos; Quality of Life; Randomized Controlled Trials as Topic; Skin Diseases; Symptom Flare Up	2021

Trials

3 trial(s) available for chloroquine and cyclosporine

Article	Year
A randomized, double-blind, 24-week controlled study of low-dose cyclosporine versus chloroquine for early rheumatoid arthritis. Arthritis and rheumatism, 1994, Volume: 37, Issue:5 Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Pressure; Chloroquine; Creatinine; Cyclosporine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Prospective Studies; Treatment Outcome	1994
Low dose cyclosporine in early rheumatoid arthritis: effective and safe after two years of therapy when compared with chloroquine. Scandinavian journal of rheumatology, 1996, Volume: 25, Issue:5 Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cyclosporine; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Radiography	1996
Combination therapy in recent onset rheumatoid arthritis: a randomized double blind trial of the addition of low dose cyclosporine to patients treated with low dose chloroquine. The Journal of rheumatology, 1998, Volume: 25, Issue:8 Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cyclosporine; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Treatment Outcome	1998

Other Studies

38 other study(ies) available for chloroquine and cyclosporine

Article	Year
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs. Antimicrobial agents and chemotherapy, 2020, 06-23, Volume: 64, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Betacoronavirus; Cell Line; Chlorocebus aethiops; Coronavirus Infections; COVID-19; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Niclosamide; Pandemics; Pneumonia, Viral; Pregnenediones; SARS-CoV-2; Vero Cells	2020
Inhibition of programmed cell death by cyclosporin. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 103, Issue:3 Topics: Animals; Apoptosis; Cell Membrane; Chloroquine; Cyclosporine; Ethylmaleimide; Membrane Proteins; Rana catesbeiana; Superoxides; Triiodothyronine	1992
Cyclosporine and chloroquine synergistically inhibit the interferon-gamma production by CD4 positive and CD8 positive synovial T cell clones derived from a patient with rheumatoid arthritis. The Journal of rheumatology, 1992, Volume: 19, Issue:9 Topics: Arthritis, Rheumatoid; CD4 Antigens; CD8 Antigens; Cells, Cultured; Chloroquine; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; Synovial Membrane; T-Lymphocytes	1992
Drug interaction of chloroquine with ciclosporin. Nephron, 1992, Volume: 62, Issue:1 Topics: Chloroquine; Cyclosporine; Drug Interactions; Humans; Kidney Failure, Chronic; Malaria; Male; Middle Aged	1992
Effects of chloroquine on antigen-presenting functions of epidermal cells from normal and psoriatic skin. The Journal of investigative dermatology, 1992, Volume: 98, Issue:2 Topics: Antigen-Presenting Cells; Chloroquine; Cyclosporine; Humans; Lymphotoxin-alpha; Psoriasis; Skin	1992
Treatment of autoimmune patients. Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 1991, Volume: 62, Issue:3-4 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Antineoplastic Agents; Autoimmune Diseases; Chloroquine; Complement C3; Complement C4; Cyclosporine; Glutamine; Humans; Immunologic Tests; Lupus Erythematosus, Systemic; Parathyroid Hormone; Taurine; Thymus Hormones; Vitamin A	1991
Chloroquine inhibits T cell proliferation by interfering with IL-2 production and responsiveness. Clinical and experimental immunology, 1995, Volume: 102, Issue:1 Topics: Antibodies, Monoclonal; Antirheumatic Agents; Base Sequence; CD3 Complex; Chloroquine; Cyclosporine; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Molecular Sequence Data; T-Lymphocytes	1995
Natural killer cell cytotoxicity and the multidrug resistance gene. Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 1 Topics: CD8 Antigens; Chloroquine; Cyclosporine; Cytotoxicity, Immunologic; DNA; Drug Resistance; Humans; Killer Cells, Natural; Membrane Glycoproteins; Perforin; Polyethylene Glycols; Polymerase Chain Reaction; Pore Forming Cytotoxic Proteins; RNA; Stearic Acids; T-Lymphocytes, Cytotoxic; Verapamil	1993
Interaction between cyclosporin and chloroquine. Nephron, 1993, Volume: 65, Issue:2 Topics: Adult; Chloroquine; Cyclosporine; Drug Interactions; Glomerulonephritis; Humans; Kidney Transplantation; Male	1993
Tyrosine phosphorylation in psoriatic T cells is modulated by drugs that induce or improve psoriasis. Dermatology (Basel, Switzerland), 1995, Volume: 191, Issue:3 Topics: Adolescent; Adult; Aged; Case-Control Studies; Cells, Cultured; Chloroquine; Cyclosporine; Ethanol; Female; Humans; Immunosuppressive Agents; Irritants; Lithium; Lymphocyte Activation; Male; Middle Aged; Phosphorylation; Phytohemagglutinins; Propranolol; Protein-Tyrosine Kinases; Psoriasis; T-Lymphocytes; Tacrolimus; Time Factors; Tyrosine	1995
Widespread pruritic plaques in a patient with subacute cutaneous lupus erythematosus and hypocomplementemia: response to dapsone therapy. Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:2 Pt 2 Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Complement C3; Complement System Proteins; Cyclosporine; Dapsone; Dermatologic Agents; Female; Humans; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Lupus Erythematosus, Cutaneous; Methylprednisolone; Prednisolone; Pruritus; Skin Diseases, Papulosquamous	1996
Synergy between lysosomotropic amines and cyclosporin A on human T cell responses to an exogenous protein antigen, tetanus toxoid. Bone marrow transplantation, 1996, Volume: 18, Issue:3 Topics: Adult; Antigens, Differentiation, B-Lymphocyte; Chloroquine; Cyclosporine; Drug Synergism; Graft vs Host Disease; Histocompatibility Antigens Class II; Humans; Hydroxychloroquine; Immunosuppressive Agents; Lymphocyte Activation; T-Lymphocytes; Tetanus Toxoid	1996
[Cyclosporine-chloroquine interactions]. Presse medicale (Paris, France : 1983), 1996, Sep-14, Volume: 25, Issue:26 Topics: Adult; Chloroquine; Cyclosporine; Drug Interactions; Humans; Male	1996
Immune suppression by lysosomotropic amines and cyclosporine on T-cell responses to minor and major histocompatibility antigens: does synergy exist? Transplantation, 1997, Oct-15, Volume: 64, Issue:7 Topics: Animals; Cell Survival; Cells, Cultured; Chloroquine; Concanavalin A; Cyclosporine; Drug Synergism; Female; Graft vs Host Disease; Histocompatibility Antigens Class II; Hydroxychloroquine; Interferon-gamma; Interleukin-2; Kinetics; Lymphocyte Activation; Lysosomes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Minor Histocompatibility Antigens; Spleen; T-Lymphocytes	1997
Autoimmune-mediated vasculopathy. Clinical immunology (Orlando, Fla.), 2001, Volume: 100, Issue:1 Topics: Adoptive Transfer; Animals; Antigens, Differentiation, B-Lymphocyte; Arteriosclerosis; Autoimmune Diseases; Chloroquine; Cyclosporine; Cytotoxicity, Immunologic; Disease Progression; Female; Graft Rejection; Graft vs Host Disease; Heart Transplantation; Histocompatibility Antigens Class II; Immunosuppressive Agents; Lymphocyte Depletion; Lymphokines; Macromolecular Substances; Postoperative Complications; Radiation Chimera; Rats; Rats, Inbred Lew; T-Lymphocytes; Th1 Cells; Th2 Cells; Thymectomy; Transplantation, Isogeneic; Tunica Intima; Tunica Media; Vasculitis	2001
Anticardiolipin antibodies in rheumatoid patients treated with etanercept or conventional combination therapy: direct and indirect evidence for a possible association with infections. Annals of the rheumatic diseases, 2002, Volume: 61, Issue:4 Topics: Adolescent; Adult; Aged; Antibodies, Anticardiolipin; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Rheumatoid; Child; Child, Preschool; Chloroquine; Cyclosporine; Drug Combinations; Etanercept; Humans; Immunoglobulin G; Immunoglobulin M; Infant; Infant, Newborn; Methotrexate; Middle Aged; Receptors, Tumor Necrosis Factor; Staphylococcal Infections; Staphylococcus aureus	2002
[Evidence-based treatment of methotrexate-resistant rheumatoid arthritis. Combinations of conventional disease-modifying antirheumatic agents]. Deutsche medizinische Wochenschrift (1946), 2003, Jan-24, Volume: 128, Issue:4 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cyclosporine; Drug Resistance; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydroxychloroquine; Immunosuppressive Agents; Isoxazoles; Leflunomide; Methotrexate; Placebos; Prednisolone; Randomized Controlled Trials as Topic; Sulfasalazine; Time Factors	2003
[Treating chronic urticaria]. MMW Fortschritte der Medizin, 2006, Aug-03, Volume: 148, Issue:31-32 Topics: Adrenal Cortex Hormones; Adult; Child; Chloroquine; Chronic Disease; Cyclosporine; Dapsone; Diagnosis, Differential; Histamine Antagonists; Humans; Pruritus; Urticaria	2006
Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity. Cell death & disease, 2018, 12-13, Volume: 9, Issue:12 Topics: 14-3-3 Proteins; Active Transport, Cell Nucleus; Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Calcineurin; Calcium; Cell Membrane; Chloroquine; Cyclosporine; Cytoplasm; Exocytosis; Humans; Indoles; Lysosomes; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Phosphorylation; Spiro Compounds	2018
Mitochondrial and lysosomal protective agents ameliorate cytotoxicity and oxidative stress induced by cyclophosphamide and methotrexate in human blood lymphocytes. Human & experimental toxicology, 2019, Volume: 38, Issue:11 Topics: Adolescent; Adult; Antineoplastic Agents; Butylated Hydroxytoluene; Cell Survival; Cells, Cultured; Chloroquine; Cyclophosphamide; Cyclosporine; Glutathione; Humans; Immunosuppressive Agents; Lymphocytes; Lysosomes; Methotrexate; Mitochondria; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Young Adult	2019
Perinatal use and discontinuation of disease-modifying anti-rheumatic drugs and biologics in women with rheumatoid arthritis: a cohort study. Rheumatology (Oxford, England), 2020, 07-01, Volume: 59, Issue:7 Topics: Abatacept; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Biological Products; British Columbia; Chloroquine; Cohort Studies; Cyclophosphamide; Cyclosporine; Deprescriptions; Female; Glucocorticoids; Gold Compounds; Humans; Hydroxychloroquine; Interleukin 1 Receptor Antagonist Protein; Leflunomide; Logistic Models; Maternal Age; Methotrexate; Mycophenolic Acid; Odds Ratio; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, First; Rheumatology; Rituximab; Sulfasalazine; Tumor Necrosis Factor Inhibitors	2020
In vitro evaluation of antiviral activity of single and combined repurposable drugs against SARS-CoV-2. Antiviral research, 2020, Volume: 181 Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Berberine; Betacoronavirus; Chlorocebus aethiops; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cyclosporine; Drug Antagonism; Drug Combinations; Drug Repositioning; Drug Synergism; Humans; Indoles; Lopinavir; Pandemics; Pneumonia, Viral; SARS-CoV-2; Vero Cells	2020