chloroquine has been researched along with cycloheximide in 114 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (60.53) | 18.7374 |
| 1990's | 24 (21.05) | 18.2507 |
| 2000's | 13 (11.40) | 29.6817 |
| 2010's | 7 (6.14) | 24.3611 |
| 2020's | 1 (0.88) | 2.80 |
| Authors | Studies |
|---|---|
| Karmodiya, K; Mishra, S; Ramya, TN; Surolia, A; Surolia, N | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Beck, HP; Brun, R; Cohen, SB; Dartois, V; Dharia, NV; Diagana, TT; Fidock, DA; Goh, A; González-Páez, GE; Jegla, T; Keller, TH; Lakshminarayana, SB; Lee, MC; McNamara, C; Nosten, F; Plouffe, DM; Renia, L; Rottmann, M; Russell, B; Schmitt, EK; Seitz, P; Spencer, KR; Suwanarusk, R; Tan, J; Winzeler, EA; Yeung, BK; Zou, B | 1 |
| Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y | 1 |
| Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL | 1 |
| Bailey, JM; Butler, J; Wu, JD | 1 |
| Mørland, B | 1 |
| Chu, LL; Cohn, DV; MacGregor, RR | 1 |
| Griffin, EE; Morton, PC; Wakeland, JR; Wildenthal, K | 1 |
| Allen, RH; Mellman, IS; Rosenberg, LE; Youngdahl-Turner, P | 1 |
| Florén, CH; Nilsson, A | 1 |
| Chajek, T; Friedman, G; Stein, O; Stein, Y | 1 |
| Carpenter, G; Cohen, S | 1 |
| Butterworth, AE | 1 |
| Artemenko, NK; Freidlin, IS; Lyzlova, SN; Nersesova, LS; Petrova, TA | 1 |
| Pandey, KN | 1 |
| Polet, H | 1 |
| Sathre, KA; Steer, CJ; Tsang, ML; Weatherbee, JA | 1 |
| Homma, S; Oppenheim, RW; Prevette, D; Tytell, M | 1 |
| Duff, GW; Symons, JA | 1 |
| Abdelrahim, MM; Burman, KD; D'Avis, JC; Lahiri, S; Tseng, YL; Wartofsky, L | 1 |
| Knutson, VP | 1 |
| Burdge, G; Garrod, DR; Mattey, DL | 1 |
| Crowley, MT; Fathman, G; Inaba, K; Puré, E; Ruberti, G; Steinman, RM; Tardelli, L; Witmer-Pack, MD | 1 |
| Blomhoff, JP; Letnes, H; Stray, N | 1 |
| Sorimachi, K; Yasumura, Y | 1 |
| Blomhoff, JP; Drevon, CA; Nossen, JO; Rustan, AC | 1 |
| Drasar, BS; Harley, VS | 1 |
| Karpati, AP; Kovacs, J | 1 |
| Kuriyama, H; Maeda, M; Neda, H; Niitsu, Y; Sone, H; Urushizaki, I; Watanabe, N; Yamauchi, N | 1 |
| Braulke, T; Gartung, C; Hasilik, A; von Figura, K | 1 |
| Banno, Y; Nozawa, Y; Sasaki, N | 1 |
| Hoekstra, S; Ku, CS; Molnar, J; Van Alten, P | 1 |
| Gallagher, ND; Robertson, JA | 1 |
| Bagchi, N; Brown, TR; Shivers, B | 1 |
| Iwaki, T; Noguchi, A; Sekimoto, T | 1 |
| Brown, MS; Davis, CG; Elhammer, A; Goldstein, JL; Kornfeld, S; Russell, DW; Schneider, WJ | 1 |
| Austgulen, R; Kildahl-Andersen, O; Nissen-Meyer, J | 1 |
| Christoffersen, T; Gladhaug, IP | 1 |
| Cooper, EL; Ghoneum, M; Smith, C | 1 |
| Komuniecki, PR; Whitten, JJ | 1 |
| Hosaka, Y; Ohara, R; Sasao, F | 1 |
| Djiane, J; Ferland, LH; Houdebine, LM; Kelly, PA; Rosa, AA | 1 |
| Knutson, VP; Lane, MD; Ronnett, GV | 1 |
| Chen, GL; Chen, WW; Frayer, KL; Sutrina, SL | 1 |
| Damerau, B; Roesler, J; Vogt, W | 1 |
| Falke, D; Kahl, GF | 1 |
| Youmans, AS; Youmans, GP | 1 |
| Baggaley, VC; Homewood, CA; Warhurst, DC | 1 |
| Sinoara, H | 1 |
| Baggaley, VC; Homewood, CA; Peters, W; Warhurst, DC | 1 |
| Hussain Qadri, SM; Williams, RP | 1 |
| Chou, SC; Conklin, KA | 2 |
| Gonasun, LM; Potts, AM | 1 |
| Aikawa, M; Cook, RT; Fournier, MJ; Rock, RC | 1 |
| Baggaley, VC; Warhurst, DC | 1 |
| Robinson, BL; Warhurst, DC | 1 |
| Howells, RE; Peters, W; Robinson, BL; Warhurst, DC | 1 |
| Bridgers, WF; Cunningham, RD; Gressett, G | 1 |
| Lazarus, L; Murphy, LJ | 1 |
| Chen, BD; Kuhn, C; Lin, HS | 1 |
| Iacopetta, BJ; Morgan, EH | 1 |
| Pesanti, EL | 1 |
| Lee, C | 1 |
| Berg, T; Carlander, B; Drevon, CA; Tolleshaug, H | 1 |
| Cuatrecasas, P; Hernaez-Davis, L; King, AC | 1 |
| DiSorbo, DM; Litwack, G; Moriarity, DM; Savage, CR | 1 |
| Dal Canto, MC; Dille, BJ; Hughes, JV; Johnson, TC; Rabinowitz, SG | 1 |
| De Groot, PG; Hollemans, M; Meera Khan, P; Ovde Elferink, RO; Strijland, A; Tager, JM; Westerveld, A | 1 |
| Delouis, C; Djiane, J; Kelly, PA | 1 |
| Djiane, J; Gandilhon, F; Gandilhon, P; Kelly, PA; Melancon, R | 1 |
| Brown, WJ; Constantinescu, E; Farquhar, MG | 1 |
| Berhanu, P; Brandenburg, D; Heidenreich, KA; Olefsky, JM | 1 |
| Oikawa, A; Saeki, H | 1 |
| Aubery, M; Codogno, P; Goussault, Y; Hornebeck, W; Robert, L | 1 |
| Griffiths, N; Lamb, JF; Ogden, P | 1 |
| Barnard, T; Drevon, CA; Nossen, JO; Rustan, AC | 1 |
| Green, A; Marshall, S; Olefsky, JM | 1 |
| Mayer, RJ; Razooki Hasan, H; White, DA | 1 |
| Eady, RP; Hallam, C; Pritchard, DI; Trigg, S | 1 |
| Slaga, TJ; Solanki, V | 1 |
| Vladutiu, GD | 1 |
| Maurer, RA | 1 |
| Henderson, KG; Muller, HK; Qu, M; Woods, GM | 1 |
| Miyabo, S; Nakai, T; Oida, K; Shimada, A; Suzuki, J; Takahashi, S; Tamai, T | 1 |
| Brandt, CS; Carlberg, K; Myles, GM; Rohrschneider, LR | 1 |
| Hirata, K; Ikeda, H; Kikuchi, K; Ohta, M; Sato, N; Takahashi, S; Ueda, D; Wada, Y | 1 |
| Gainey, D; Inman, JK; McCoy, KL; Stutzman, R | 1 |
| Lodish, HF; Neumann, D; Watowich, SS; Wikström, L | 1 |
| Babior, BM; Gottlieb, RA; Nordberg, J; Skowronski, E | 1 |
| Kang, BK; Spaziani, E | 1 |
| Alonso, M; Hendricks, L; Hidalgo, J; Velasco, A | 1 |
| Chou, AC; Fitch, CD | 1 |
| Aldieri, E; Bosia, A; Costamagna, C; Garbarino, G; Ghigo, D; Pescarmona, G; Todde, R | 1 |
| Harney, J; Larsen, PR; Steinsapir, J | 1 |
| Everitt, E; Rodríguez, E | 1 |
| Amara, SG; Daniels, GM | 1 |
| Fayadat, L; Franc, JL; Lanet, J; Siffroi-Fernandez, S | 1 |
| Harada, M; Morita, A; Nakayama, E; Ono, T; Ota, S; Uenaka, A | 1 |
| Arai, H; Arita, M; Horiguchi, M; Inoue, K; Kaempf-Rotzoll, DE; Tsujimoto, M | 1 |
| Emerson, LR; Kuchler, K; Skillman, BC; Wirth, DF; Wolfger, H | 1 |
| Cowan, JW; Deng, L; Frank, SJ; He, K; Jiang, J; Li, X; Loesch, K; Wang, X | 1 |
| Fried, SK; Lee, MJ | 1 |
| Deng, L; Frank, SJ; Fuchs, SY; He, K; Jiang, J; Thangavel, C; Wang, X; Yang, N | 1 |
| Li, ML; Shih, SR; Stollar, V; Weng, KF | 1 |
| Ganapathy, V; Kashiwagi, H; Sugawara, M; Takekuma, Y; Yamazaki, K | 1 |
| Suzuki, K; Taniura, H; Yamamoto, N | 1 |
| Lefort, R; Pozueta, J; Shelanski, M | 1 |
| Auparakkitanon, S; Utaida, S; Wilairat, P | 1 |
| Fagerlund, R; Fortmann, KT; Hoffmann, A; Lewis, RD; Ngo, KA | 1 |
| Choi, HS; Kim, KJ; Kumar, S; Lee, B; Lee, K; Park, E; Seo, JE | 1 |
1 review(s) available for chloroquine and cycloheximide
| Article | Year |
|---|---|
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization | 2021 |
113 other study(ies) available for chloroquine and cycloheximide
| Article | Year |
|---|---|
Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum.
Topics: Acetone; Animals; Antimalarials; Azithromycin; Cerulenin; Chloramphenicol; Clindamycin; Erythrocytes; Fatty Acids; Gene Dosage; Humans; Organelles; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Tetracycline; Thioctic Acid; Triclosan | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Spiroindolones, a potent compound class for the treatment of malaria.
Topics: Adenosine Triphosphatases; Animals; Antimalarials; Cell Line; Drug Discovery; Drug Resistance; Erythrocytes; Female; Genes, Protozoan; Humans; Indoles; Malaria; Male; Mice; Models, Molecular; Mutant Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Plasmodium vivax; Protein Synthesis Inhibitors; Protozoan Proteins; Rats; Rats, Wistar; Spiro Compounds | 2010 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites | 2011 |
Lipid metabolism in cultured cells. XVIII. Comparative uptake of low density and high density lipoproteins by normal, hypercholesterolemic and tumor virus-transformed human fibroblasts.
Topics: Animals; Biological Transport; Cell Line; Cell Transformation, Viral; Chloroquine; Cycloheximide; Heterozygote; Homozygote; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Lung; Mice; Oncogenic Viruses; Skin | 1979 |
Studies on selective induction of lysosomal enzyme activities in mouse peritoneal macrophages.
Topics: Acid Phosphatase; Animals; Cathepsins; Cell Membrane; Chloroquine; Colchicine; Culture Media; Cycloheximide; Cytochalasin B; Dactinomycin; Endocytosis; Endotoxins; Glucuronidase; L-Lactate Dehydrogenase; Latex; Lysosomes; Macrophages; Mice; Microspheres; Subcellular Fractions; Trypsin | 1979 |
Energy-dependent intracellular translocation of proparathormone.
Topics: Anaerobiosis; Animals; Antimycin A; Cattle; Chloroquine; Colchicine; Cycloheximide; Cytochalasin B; Deoxyglucose; Deuterium; Dinitrophenols; In Vitro Techniques; Kinetics; Oligomycins; Parathyroid Glands; Parathyroid Hormone; Rotenone; Temperature; Tromethamine; Vinblastine | 1977 |
Inhibition of protein degradation in mouse hearts by agents that cause lysosomal dysfunction.
Topics: Amino Acids; Animals; Chloroquine; Cycloheximide; Fetal Heart; Lysosomes; Mice; Organ Culture Techniques; Proteins; Sucrose | 1978 |
Protein mediated vitamin uptake. Adsorptive endocytosis of the transcobalamin II-cobalamin complex by cultured human fibroblasts.
Topics: Azides; Blood Proteins; Cell Line; Cell Membrane; Chloroquine; Cycloheximide; Endocytosis; Fluorides; Receptors, Drug; Transcobalamins; Vitamin B 12 | 1979 |
Degradation of chylomicron remnant cholesteryl ester by rat hepatocyte monolayers. Inhibition by chloroquine and colchicine.
Topics: Animals; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Chylomicrons; Colchicine; Cycloheximide; Kinetics; Liver; Male; Rats | 1977 |
Effect of colchicine, cycloheximide and chloroquine on the hepatic triacylglycerol hydrolase in the intact rat and perfused liver.
Topics: Animals; Chloroquine; Colchicine; Cycloheximide; Half-Life; Heparin; Kinetics; Lipase; Liver; Male; Perfusion; Rats; Triglycerides | 1977 |
125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.
Topics: Ammonium Chloride; Anesthetics, Local; Azides; Binding, Competitive; Cell Membrane; Chloroquine; Cyanides; Cycloheximide; Dinitrophenols; Epidermal Growth Factor; Fibroblasts; Fluorides; Humans; Iodine Radioisotopes; Kinetics; Peptides; Temperature; Trypsin Inhibitors | 1976 |
Nonspecific cytotoxic effects of antigen-transformed lymphocytes. II. Inhibition by drugs.
Topics: Cells, Cultured; Chloroquine; Cycloheximide; Cytotoxicity Tests, Immunologic; Dactinomycin; Humans; Lymphocyte Activation; Lymphocytes; Mitomycins; Prednisolone; Thymidine; Tritium; Tuberculin | 1975 |
[Changes in the functional activity of macrophages, their morphology and metabolism under the influence of several biologically active substances].
Topics: Ascorbic Acid; Carbon Radioisotopes; Cathepsins; Chloramphenicol; Chloroquine; Creatine Kinase; Culture Techniques; Cycloheximide; Dactinomycin; Lipopolysaccharides; Lysine; Macrophages; Orotic Acid; Peritoneum; Phagocytosis; Protein Biosynthesis; Puromycin; Rifampin; RNA; Tetracycline; Uridine | 1975 |
Kinetic analysis of internalization, recycling and redistribution of atrial natriuretic factor-receptor complex in cultured vascular smooth-muscle cells. Ligand-dependent receptor down-regulation.
Topics: Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cells, Cultured; Chloroquine; Cycloheximide; Dinitrophenols; Down-Regulation; Endocytosis; Kinetics; Muscle, Smooth, Vascular; Rats; Receptors, Atrial Natriuretic Factor | 1992 |
Effects of platelet-derived growth factor on degradation, nuclear translocation of nonhistone proteins, and DNA synthesis.
Topics: Animals; Biological Transport; Cell Division; Cell Nucleus; Chloroquine; Cycloheximide; DNA; Lysosomes; Platelet-Derived Growth Factor; Proteins; Rats | 1992 |
Binding and internalization of transforming growth factor-beta 1 by human hepatoma cells: evidence for receptor recycling.
Topics: Binding, Competitive; Carcinoma, Hepatocellular; Chloroquine; Cycloheximide; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Monensin; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured | 1991 |
Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: evidence for the role of cell death genes.
Topics: Animals; Cell Survival; Chick Embryo; Chloroquine; Curare; Cycloheximide; Dactinomycin; Ganglia, Spinal; Gene Expression; Genotype; Leupeptins; Microscopy, Electron; Motor Neurons; Protein Biosynthesis; Puromycin; RNA; Spinal Cord | 1990 |
A soluble form of the interleukin-1 receptor produced by a human B cell line.
Topics: Aprotinin; B-Lymphocytes; Cell Line; Chloroquine; Cycloheximide; Dactinomycin; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Humans; Interleukin-1; Kinetics; Monensin; Protease Inhibitors; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins | 1990 |
Thyrotropin modulates receptor-mediated processing of the atrial natriuretic peptide receptor in cultured thyroid cells.
Topics: Cells, Cultured; Chloroquine; Cycloheximide; Humans; Iodine Radioisotopes; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thyroid Gland; Thyrotropin | 1991 |
Proteolytic processing of the insulin receptor beta subunit is associated with insulin-induced receptor down-regulation.
Topics: Animals; Blotting, Western; Cells, Cultured; Chloroquine; Cycloheximide; Cysteine Endopeptidases; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Insulin; Insulin Antagonists; Leucine; Leupeptins; Mice; Peptide Fragments; Receptor, Insulin | 1991 |
Development of desmosomal adhesion between MDCK cells following calcium switching.
Topics: Animals; Calcium; Cell Adhesion; Cell Line; Chloroquine; Chromatography, Affinity; Cycloheximide; Cytoplasm; Cytoskeletal Proteins; Desmocollins; Desmoplakins; Desmosomes; Dogs; Fluorescent Antibody Technique; Immunoblotting; Kinetics; Membrane Proteins | 1990 |
Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain.
Topics: Animals; Antigen-Presenting Cells; Cells, Cultured; Chloroquine; Cycloheximide; Dendritic Cells; Down-Regulation; Female; Gene Expression; Histocompatibility Antigens Class II; Hybridomas; Immunoglobulin gamma-Chains; Langerhans Cells; Lymphocytes; Mice; Microscopy, Fluorescence; Ovalbumin; Rhodamines; T-Lymphocytes | 1990 |
Intracellular regulation of lipoprotein lipase in human monocyte-derived macrophages.
Topics: Cell Differentiation; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Humans; In Vitro Techniques; Lipoprotein Lipase; Macrophages; Monensin; Monocytes; Secretory Rate; Tunicamycin | 1990 |
Regulation of alkaline phosphatase activity in rat hepatoma cells. Effects of serum proteins, cycloheximide, actinomycin D, chloroquine, dinitrophenol and potassium cyanide.
Topics: Alkaline Phosphatase; Animals; Blood; Blood Proteins; Cell Line; Chloroquine; Cycloheximide; Dactinomycin; Dinitrophenols; Electrophoresis, Polyacrylamide Gel; Homoarginine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver Neoplasms, Experimental; Phenylalanine; Potassium Cyanide; Protein Biosynthesis; Rats | 1986 |
Release of hepatic lipase and very low density lipoprotein by cultured rat hepatocytes.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Chloroquine; Colchicine; Cycloheximide; Dextrans; Heparin; Lipase; Lipoproteins, VLDL; Liver; Oleic Acid; Oleic Acids; Rats | 1986 |
Interaction of Legionella pneumophila with tissue culture cells.
Topics: Ammonium Chloride; Cell Division; Chloroquine; Cycloheximide; HeLa Cells; Humans; Legionella | 1989 |
Regression of autophagic vacuoles in mouse pancreatic cells: a morphometric study of the effect of methylamine and chloroquine followed by cycloheximide treatment.
Topics: Animals; Autophagy; Chloroquine; Cycloheximide; Male; Methylamines; Mice; Pancreas; Phagocytosis; Vacuoles | 1989 |
[Continuous internalization of TNF receptors in a human myosarcoma cell line].
Topics: Cell Line; Chloroquine; Cycloheximide; Humans; Myosarcoma; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Sarcoma; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1988 |
Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes?
Topics: Ammonium Chloride; Carrier Proteins; Cathepsin D; Cell Membrane; Cells, Cultured; Chloroquine; Cycloheximide; Humans; Intracellular Membranes; Lysosomes; Mannosephosphates; Monensin; Receptor, IGF Type 2 | 1987 |
Secretion heterogeneity of lysosomal enzymes in Tetrahymena pyriformis.
Topics: Acid Phosphatase; Age Factors; alpha-Mannosidase; Ammonium Chloride; Animals; Azides; beta-Galactosidase; beta-N-Acetylhexosaminidases; Cell Compartmentation; Chloroquine; Cycloheximide; Extracellular Space; Glucosidases; Lysosomes; Mannosidases; Sodium Azide; Starvation; Tetrahymena pyriformis | 1987 |
Evidence for the recycling nature of the fibronectin receptor of macrophages.
Topics: Animals; Carrier Proteins; Chloroquine; Cycloheximide; Fibronectins; Macrophages; Peptide Hydrolases; Phagocytosis; Protein Binding; Protein Conformation; Rats; Receptors, Fibronectin; Receptors, Immunologic; Temperature | 1987 |
In vivo evidence that cobalamin is absorbed by receptor-mediated endocytosis in the mouse.
Topics: Animals; Biological Transport; Chloroquine; Cycloheximide; Endocytosis; Intestinal Absorption; Lysosomes; Mice; Receptors, Cell Surface; Vitamin B 12 | 1985 |
Studies on the mechanism of acute inhibition of thyroglobulin hydrolysis by iodine.
Topics: Ammonium Chloride; Animals; Bucladesine; Cells, Cultured; Chloroquine; Cycloheximide; Dactinomycin; Female; Hydrolysis; Iodine; Methimazole; Mice; Sodium Iodide; Thyroglobulin; Thyroid Gland; Time Factors | 1985 |
Sources of extramitochondrial corticoidogenic cholesterol in the adrenal cortex.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Calcium; Cattle; Chloroquine; Cholesterol; Cricetinae; Cycloheximide; Dichlorvos; Female; In Vitro Techniques; Lovastatin; Male; Mesocricetus; Naphthalenes; Rats; Rats, Inbred Strains; Species Specificity; Sulfonamides | 1985 |
Deletion of clustered O-linked carbohydrates does not impair function of low density lipoprotein receptor in transfected fibroblasts.
Topics: Amino Acid Sequence; Animals; Carbohydrates; Cell Line; Chloroquine; Chromatography, Affinity; Chromatography, Paper; Cricetinae; Cricetulus; Cycloheximide; DNA; Female; Fibroblasts; Glucosamine; Humans; Molecular Weight; Monensin; Ovary; Receptors, LDL; Simian virus 40; Transfection; Tunicamycin | 1986 |
Human monocyte-released cytotoxic factor: effect on various cellular functions, and dependency of cytolysis on various metabolic processes.
Topics: Adenosine Triphosphate; Cell Survival; Chloroquine; Colchicine; Cycloheximide; Cytotoxicity, Immunologic; Cytotoxins; Dactinomycin; Humans; Mitomycin; Mitomycins; Monocytes; Nucleic Acids; Protein Biosynthesis; Ricin; Uncoupling Agents | 1986 |
Rapid constitutive internalization and externalization of epidermal growth factor receptors in isolated rat hepatocytes. Monensin inhibits receptor externalization and reduces the capacity for continued endocytosis of epidermal growth factor.
Topics: Animals; Cell Membrane; Chloroquine; Cycloheximide; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Kinetics; Liver; Male; Monensin; Rats; Rats, Inbred Strains; Tunicamycin | 1988 |
Inhibition of SK cell activity in frogs by certain drugs and sugars.
Topics: Animals; Carbohydrates; Cell Line; Chloroquine; Colchicine; Cycloheximide; Cytotoxicity, Immunologic; Erythrocytes; Female; Humans; Killer Cells, Natural; Male; Neoplasms, Experimental; Rana pipiens | 1987 |
Brugia pahangi: inhibition of protein synthesis.
Topics: Animals; Antimycin A; Brugia; Chloramphenicol; Chloroquine; Cyanides; Cycloheximide; Electron Transport; Lactates; Molecular Weight; Movement; Protein Biosynthesis; Protein Synthesis Inhibitors; Quinacrine | 1987 |
Cell-mediated lysis of heat-inactivated influenza virus-coated murine targets.
Topics: Animals; Antigens, Viral; Chloroquine; Cross Reactions; Cycloheximide; Dactinomycin; H-2 Antigens; Hemagglutinins, Viral; Hot Temperature; In Vitro Techniques; Mice; Mice, Inbred Strains; Orthomyxoviridae; T-Lymphocytes, Cytotoxic; Ultraviolet Rays | 1985 |
Maintenance of prolactin (PRL) binding sites in rat liver cells in suspension culture: effect of PRL and of inhibitors of various cellular functions.
Topics: Animals; Binding Sites; Cells, Cultured; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Dinitrophenols; Female; Histological Techniques; Liver; Prolactin; Rats | 1985 |
The effects of cycloheximide and chloroquine on insulin receptor metabolism. Differential effects on receptor recycling and inactivation and insulin degradation.
Topics: Animals; Cell Line; Chloroquine; Cycloheximide; Dactinomycin; Fibroblasts; Insulin; Kinetics; Mice; Pactamycin; Protein Biosynthesis; Puromycin; Receptor, Insulin; RNA, Messenger | 1985 |
Effects of lysosomotropic agents on lipogenesis.
Topics: Acetates; Ammonium Chloride; Cells, Cultured; Chloroquine; Choline; Cycloheximide; Fibroblasts; Humans; Hydrogen-Ion Concentration; Lipids; Lysosomes; Palmitates; Pyruvates; Quinine; Water | 1986 |
Pharmacological characterization of the slow component of deactivation of guinea-pig isolated ileum to the spasmogenic action of C5adesArg.
Topics: Animals; Chloroquine; Colchicine; Complement C5; Complement C5a, des-Arginine; Cycloheximide; Cytochalasin B; Guinea Pigs; Ileum; In Vitro Techniques; Lumicolchicines; Muscle Contraction; Muscle, Smooth; Vinblastine | 1985 |
The inhibitory effect of compound 48-80 on the formation of giant cells induced by herpesvirus hominis.
Topics: Amino Acids; Animals; Cell Count; Chloroquine; Choline; Cromolyn Sodium; Culture Techniques; Cycloheximide; Cytopathogenic Effect, Viral; DNA; Fluorometry; Heparin; Histamine Release; Hydrazines; Isonicotinic Acids; Kidney; Lipids; Lysosomes; Macrophages; p-Methoxy-N-methylphenethylamine; Protein Biosynthesis; Quaternary Ammonium Compounds; Rabbits; Rats; RNA; Simplexvirus; Staining and Labeling; Thymidine; Time Factors; Tritium; Uridine | 1971 |
The effect of metabolic inhibitors and hydroxylamine on the immune response in mice to mycobacterial ribonucleic acid vaccines.
Topics: Animals; Antibody Formation; Antimetabolites; Bacterial Vaccines; Chloramphenicol; Chloroquine; Cycloheximide; Dactinomycin; Ethidium; Flavins; Floxuridine; Hemagglutination Tests; Hydroxylamines; Male; Mice; Mycobacterium tuberculosis; Rifampin; RNA, Bacterial; Streptomycin; Vaccination | 1974 |
The chemotherapy of rodent malaria. XX. Autophagic vacuole formation in Plasmodium berghei in vitro.
Topics: Animals; Anti-Bacterial Agents; Chloroquine; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Erythrocytes; In Vitro Techniques; Inclusion Bodies; Malaria; Mice; Pigments, Biological; Plasmodium berghei; Protein Biosynthesis; Puromycin; Time Factors; Vacuoles | 1974 |
Amino acid transport in spores of Aspergillus oryzae.
Topics: Acridines; Amino Acids; Arginine; Aspergillus; Biological Transport; Carbon Radioisotopes; Cell Membrane; Chloroquine; Chlorpromazine; Cycloheximide; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Leucine; Mannitol; Naphthalenesulfonates; Osmolar Concentration; Phosphates; Potassium Chloride; Pronase; Salicylates; Sodium Dodecyl Sulfate; Spores, Fungal; Time Factors | 1974 |
Lysosomes, pH and the anti-malarial action of chloroquine.
Topics: Animals; Chloroquine; Cycloheximide; Drug Resistance, Microbial; Erythrocytes; Hydrogen-Ion Concentration; Lysosomes; Malaria; Mammals; Plasmodium | 1972 |
Biosynthesis of the tripyrrole bacterial pigment, prodigiosin, by nonproliferating cells of Serratia marcescens.
Topics: Amino Acids; Anti-Bacterial Agents; Carbon Isotopes; Cell Count; Chloramphenicol; Chloroquine; Cycloheximide; Dactinomycin; Fluorouracil; Kinetics; Mitomycins; Pigments, Biological; Prodigiosin; Proteins; Puromycin; Pyrroles; Serratia marcescens; Streptomycin; Temperature; Tryptophan | 1972 |
The effects of antimalarial drugs on uptake and incorporation of macromolecular precursors by Tetrahymena pyriformis.
Topics: Amino Acids; Animals; Antimalarials; Carbon Isotopes; Cell Division; Chloroquine; Cycloheximide; Dactinomycin; DNA; Kinetics; Macromolecular Substances; Nalidixic Acid; Primaquine; Quinacrine; Quinine; RNA; Tetrahymena pyriformis; Thymidine; Uridine | 1972 |
In vitro inhibition of protein synthesis in the retinal pigment epithelium by chloroquine.
Topics: Animals; Carbon Radioisotopes; Cattle; Chloroquine; Cycloheximide; Epithelium; Eye Proteins; Hydroxychloroquine; In Vitro Techniques; Leucine; Lysine; Phenylalanine; Puromycin; Quinine; Retina; Tissue Extracts | 1974 |
Ribosomes of the malarial parasite, Plasmodium knowlesi. I. Isolation, activity and sedimentation velocity.
Topics: Amino Acids; Animals; Bile Acids and Salts; Biological Evolution; Carbon Isotopes; Cell Fractionation; Chloramphenicol; Chloroquine; Cycloheximide; Dialysis; Filtration; Haplorhini; Kinetics; Macaca; Magnesium; Microscopy, Electron; Plasmodium; Protein Biosynthesis; Puromycin; Ribosomes; Streptomycin; Ultracentrifugation | 1971 |
Autophagic vacuole formation in P. berghei in vitro.
Topics: Antimalarials; Chloroquine; Culture Media; Cycloheximide; Dactinomycin; Methods; Pigments, Biological; Plasmodium; Protein Biosynthesis; RNA; Rotenone | 1972 |
Cytotoxic agents and haemozoin pigment in malaria parasites (Plasmodium berghei).
Topics: Animals; Antineoplastic Agents; Azaserine; Chloramphenicol; Chloroquine; Cycloheximide; Cytoplasm; Dactinomycin; Injections, Intraperitoneal; Malaria; Male; Mercaptopurine; Mice; Mitomycins; Nucleic Acids; Pigments, Biological; Plasmodium; Protein Biosynthesis; Puromycin; Streptomycin; Tetracycline; Uracil | 1971 |
The effect of cytotoxic agents on autophagic vacuole formation in chloroquine-treated malaria parasites (Plasmodium berghei).
Topics: Animals; Antineoplastic Agents; Azaserine; Chloroquine; Colchicine; Cycloheximide; Cytoplasm; Dactinomycin; Malaria; Mercaptopurine; Mice; Mitomycins; Nucleic Acids; Pigments, Biological; Plasmodium; Protein Biosynthesis; Ribosomes; Uracil | 1971 |
Properties distinguishing mitochondrial and synaptosomal protein synthesis.
Topics: Animals; Brain; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Chloroquine; Cycloheximide; Depression, Chemical; Drug Antagonism; Emetine; Leucine; Mice; Mitochondria; Nerve Endings; Nerve Tissue Proteins; Synaptic Vesicles; Synaptosomes | 1971 |
Antimalarials: effects on in vivo and in vitro protein synthesis.
Topics: Amino Acids; Antimalarials; Carbon Isotopes; Cell-Free System; Chloroquine; Cycloheximide; Primaquine; Protein Biosynthesis; Quinacrine; Quinine; Tetrahymena | 1970 |
The mouse fibroblast growth hormone receptor: ligand processing and receptor modulation and turnover.
Topics: Animals; Antimetabolites; Cell Line; Chloroquine; Cycloheximide; Fibroblasts; Mice; Mice, Inbred BALB C; Receptors, Cell Surface; Receptors, Somatotropin; Time Factors | 1984 |
Receptor-mediated binding and internalization of colony-stimulating factor (CSF-1) by mouse peritoneal exudate macrophages.
Topics: Animals; Ascitic Fluid; Autoradiography; Cells, Cultured; Chloroquine; Colony-Stimulating Factors; Cycloheximide; Histocytochemistry; Macrophages; Male; Mice; Mice, Inbred C3H; Microscopy, Electron; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Temperature | 1984 |
The kinetics of transferrin endocytosis and iron uptake from transferrin in rabbit reticulocytes.
Topics: Acyltransferases; Ammonium Chloride; Animals; Chloroquine; Cycloheximide; Endocytosis; Iron; Kinetics; Rabbits; Reticulocytes; Temperature; Transferrin; Transglutaminases | 1983 |
In vitro effects of antiprotozoan drugs and immune serum on Pneumocystis carinii.
Topics: Animals; Antiprotozoal Agents; Chloroquine; Cycloheximide; Idoxuridine; Immune Sera; Iodoacetates; Pneumocystis; Rabbits; Staining and Labeling | 1980 |
Physiology of castration-induced regression in rat prostate.
Topics: Animals; Atrophy; Castration; Cathepsin D; Cathepsins; Chloroquine; Cycloheximide; Dactinomycin; Male; Microscopy, Electron; Organ Size; Prostate; Proteins; Rats; Rats, Inbred Strains; RNA | 1981 |
Metabolism of asialoglycoproteins in cultured rat hepatocytes: evidence for receptor mediated uptake and degradation which is not feed-back regulated.
Topics: alpha-Fetoproteins; Ammonium Chloride; Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Cells, Cultured; Chloroquine; Cycloheximide; Fetuins; Leupeptins; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface | 1983 |
Lysomotropic amines cause intracellular accumulation of receptors for epidermal growth factor.
Topics: Amines; Animals; Cells, Cultured; Chloroquine; Cycloheximide; Epidermal Growth Factor; ErbB Receptors; Humans; Methylamines; Mice; Peptides; Pinocytosis; Receptors, Cell Surface; Time Factors; Trypsin | 1980 |
Epidermal growth factor stimulation of ornithine decarboxylase activity in a human hepatoma cell line.
Topics: Ammonium Chloride; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Enzyme Induction; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Liver Neoplasms; Ornithine Decarboxylase; Peptides; Receptors, Cell Surface | 1981 |
Cytopathic effects in mouse neuroblastoma cells during a non-permissive infection with a mutant of vesicular stomatitis virus.
Topics: Animals; Cell Fusion; Cell Line; Chloroquine; Cycloheximide; Cytopathogenic Effect, Viral; Dactinomycin; Mice; Mitochondria; Mutation; Neuroblastoma; Neurons; Vacuoles; Vesicular stomatitis Indiana virus | 1981 |
Inactivation by chloroquine of alpha-galactosidase in cultured human skin fibroblasts.
Topics: alpha-Galactosidase; Ammonium Chloride; Cells, Cultured; Chloroquine; Culture Media; Cycloheximide; Dose-Response Relationship, Drug; Fibroblasts; Galactosidases; Glucuronidase; Hexosaminidases; Humans | 1981 |
Prolactin receptor turnover in explants of pseudopregnant rabbit mammary gland.
Topics: 2,4-Dinitrophenol; Animals; Chloroquine; Cycloheximide; Dactinomycin; Dinitrophenols; Female; Lysosomes; Mammary Glands, Animal; Organ Culture Techniques; Ouabain; Prolactin; Pseudopregnancy; Rabbits; Receptors, Cell Surface | 1982 |
Prolactin receptors in explant cultures of carcinogen-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chloroquine; Colchicine; Cycloheximide; Cytochalasin B; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Organoids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prolactin | 1983 |
Redistribution of mannose-6-phosphate receptors induced by tunicamycin and chloroquine.
Topics: Animals; Cells, Cultured; Chloroquine; Coated Pits, Cell-Membrane; Cycloheximide; Fluorescent Antibody Technique; Glucosamine; Immunoenzyme Techniques; Liver; Microscopy, Electron; Rats; Receptor, IGF Type 2; Receptors, Cell Surface; Tissue Distribution; Tunicamycin | 1984 |
Degradation of insulin receptors in rat adipocytes.
Topics: Adipose Tissue; Affinity Labels; Animals; Autoradiography; Azides; Chloroquine; Cycloheximide; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Insulin; Iodine Radioisotopes; Kinetics; Male; Photochemistry; Rats; Rats, Inbred Strains; Receptor, Insulin | 1983 |
Stimulation of tyrosinase activity of cultured melanoma cells by lysosomotropic agents.
Topics: Ammonium Chloride; Animals; Catechol Oxidase; Cell Line; Chloroquine; Cycloheximide; Ethylamines; Hydrogen-Ion Concentration; Imidazoles; Melanins; Melanoma; Methylamines; Mice; Monophenol Monooxygenase | 1983 |
Elastase activity in chick embryo fibroblasts, quantitative changes induced by agents which affect cell functions and variations during embryogenesis.
Topics: Animals; Cell Differentiation; Chick Embryo; Chloroquine; Colchicine; Cycloheximide; Fibroblasts; Pancreatic Elastase; Tunicamycin; Vinblastine | 1983 |
The effects of chloroquine and other weak bases on the accumulation and efflux of digoxin and ouabain in HeLa cells.
Topics: Amantadine; Biological Transport, Active; Chloroquine; Cycloheximide; Digoxin; HeLa Cells; Humans; Ouabain; Potassium; Sodium | 1983 |
Inhibition by chloroquine of the secretion of very low density lipoproteins by cultured rat hepatocytes.
Topics: Animals; Cells, Cultured; Chloroquine; Cycloheximide; Dose-Response Relationship, Drug; Endocytosis; Lipoproteins, VLDL; Liver; Lysosomes; Protein Biosynthesis; Rats; Secretory Rate; Triglycerides | 1984 |
Evidence for recycling of insulin receptors in isolated rat adipocytes.
Topics: Adipose Tissue; Animals; Buffers; Chloroquine; Cycloheximide; In Vitro Techniques; Insulin; Kinetics; Male; Protein Biosynthesis; Rats; Rats, Inbred Strains; Receptor, Insulin | 1981 |
Extensive destruction of newly synthesized casein in mammary explants in organ culture.
Topics: Animals; Caseins; Chloroquine; Cycloheximide; Fatty Acid Synthases; Female; Hexosamines; Leucine; Mammary Glands, Animal; Organ Culture Techniques; Pregnancy; Proline; Rabbits | 1982 |
Rat eosinophil-mediated antibody-dependent cellular cytotoxicity: investigations of the mechanisms of target cell lysis and inhibition by glucocorticoids.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Chloroquine; Colchicine; Cycloheximide; Cytochalasin B; Eosinophils; Female; Methylprednisolone; Rats; Rats, Inbred Strains; Receptors, Fc | 1982 |
The down-modulation of receptors for phorbol ester tumor promoter in primary epidermal cells.
Topics: Animals; Arginine; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Chloroquine; Chlorpromazine; Cycloheximide; Epidermis; Mice; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Solubility | 1982 |
The effect of chloroquine on the distribution of newly synthesized and old beta-hexosaminidase in fibroblasts.
Topics: Acetylglucosaminidase; Cells, Cultured; Chloroquine; Cycloheximide; Endocytosis; Fibroblasts; Hexosaminidases; Humans; Leucine; Mannosephosphates | 1982 |
Bromoergocryptine-induced prolactin degradation in cultured pituitary cells.
Topics: Animals; Bromocriptine; Cells, Cultured; Chloroquine; Cycloheximide; Female; Kinetics; Pituitary Gland; Prolactin; Rats | 1980 |
Processing of complex antigens and simple hapten-like molecules by epidermal Langerhans cells.
Topics: Animals; Antigen Presentation; Chloroquine; Cycloheximide; Cytochalasin B; Dermatitis, Contact; Female; Langerhans Cells; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Monensin; Ovalbumin; Skin; Trinitrobenzenes | 1995 |
Increase in neutral cholesteryl ester hydrolase activity produced by extralysosomal hydrolysis of high-density lipoprotein cholesteryl esters in rat hepatoma cells (H-35).
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Cholesterol; Cholesterol Esters; Cycloheximide; Cytoplasm; Lipoproteins, HDL; Rats; Sterol Esterase | 1994 |
Tyrosine 569 in the c-Fms juxtamembrane domain is essential for kinase activity and macrophage colony-stimulating factor-dependent internalization.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chloroquine; Cloning, Molecular; Cycloheximide; Endocytosis; Glycophorins; Kinetics; Lysosomes; Macrophage Colony-Stimulating Factor; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Protein-Tyrosine Kinases; Rats; Receptor, Macrophage Colony-Stimulating Factor; Recombinant Fusion Proteins; Sequence Deletion; Signal Transduction; Transfection; Tyrosine | 1994 |
Brefeldin A blocks the cytotoxicity of T cell receptor alpha/beta and gamma/delta cytotoxic T lymphocyte clones reacting against human autologous cancer cells.
Topics: Brefeldin A; Chloroquine; Colchicine; Cycloheximide; Cyclopentanes; Cytotoxicity Tests, Immunologic; Humans; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1993 |
Antigen presentation by B lymphoma cells. Requirements for processing of exogenous antigen internalized through transferrin receptors.
Topics: Antigen Presentation; Antigen-Presenting Cells; Cell Line; Chloroquine; Cycloheximide; Cytochrome c Group; Humans; Lymphoma, B-Cell; Receptors, Transferrin; Tumor Cells, Cultured | 1993 |
Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes.
Topics: 3T3 Cells; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Cycloheximide; Endoplasmic Reticulum; Golgi Apparatus; Hexosaminidases; Leupeptins; Lysosomes; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Peptide Fragments; Receptors, Erythropoietin | 1993 |
Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification.
Topics: Acids; Alkalies; Apoptosis; Cell Line; Cell Nucleus; Ceramides; Chloroquine; Cycloheximide; DNA; Endonucleases; fas Receptor; Flow Cytometry; Hydrogen-Ion Concentration; Imidazoles; Immunologic Capping; Ploidies; T-Lymphocytes; Ultraviolet Rays | 1996 |
Uptake of high-density lipoprotein by Y-organs of the crab Cancer antennarius: III. Evidence for adsorptive endocytosis and the absence of lysosomal processing.
Topics: Animals; Brachyura; Chloroquine; Cycloheximide; Endocrine Glands; Endocytosis; Female; Immunohistochemistry; Lipoproteins, HDL; Lysosomes; Time Factors | 1995 |
Degradation of aggrecan precursors within a specialized subcompartment of the chicken chondrocyte endoplasmic reticulum.
Topics: Aggrecans; Ammonium Chloride; Animals; Azides; Calcium; Cartilage; Cells, Cultured; Chick Embryo; Chloroquine; Chondroitin Sulfate Proteoglycans; Cycloheximide; Cysteine Endopeptidases; Endoplasmic Reticulum, Smooth; Extracellular Matrix Proteins; Fluorescent Antibody Technique; Lectins, C-Type; Lysosomes; Oxidation-Reduction; Protease Inhibitors; Protein Precursors; Proteoglycans; Serine Endopeptidases; Sodium Azide; Temperature | 1996 |
Regulation of heme polymerizing activity and the antimalarial action of chloroquine.
Topics: Animals; Antimalarials; Chloroquine; Cycloheximide; Erythrocytes; Hemin; Injections, Intraperitoneal; Male; Mice; Plasmodium berghei; Polymers; Quinine; Transferases | 1997 |
Chloroquine stimulates nitric oxide synthesis in murine, porcine, and human endothelial cells.
Topics: Aconitate Hydratase; Animals; Calcium; Canavanine; Cell Division; Cell Line, Transformed; Chloroquine; Cycloheximide; Cytosol; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Guanidines; Heme; Humans; Hydrogen-Ion Concentration; Iron; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ornithine Decarboxylase; Protein Synthesis Inhibitors; Stimulation, Chemical; Swine | 1998 |
Type 2 iodothyronine deiodinase in rat pituitary tumor cells is inactivated in proteasomes.
Topics: Adenosine Triphosphate; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chloroquine; Cycloheximide; Cysteine Endopeptidases; Cytochalasin B; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Isoenzymes; Leupeptins; Multienzyme Complexes; Neoplasm Proteins; Pituitary Neoplasms; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Rats; Thyroxine; Triiodothyronine, Reverse; Tumor Cells, Cultured; Ubiquitins | 1998 |
Adenovirus cellular receptor site recirculation of HeLa cells upon receptor-mediated endocytosis is not low pH-dependent.
Topics: Adenoviruses, Human; Amantadine; Ammonium Chloride; Chloroquine; Cycloheximide; Endocytosis; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Methionine; Monensin; Nigericin; Receptors, Virus; Sulfur Radioisotopes | 1999 |
Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters.
Topics: Acetylcysteine; Animals; Carrier Proteins; Cell Line; Chloroquine; Clathrin; Colforsin; Cycloheximide; Dogs; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocytosis; Enzyme Activation; Humans; Kinetics; Lysosomes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phorbols; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Degradation of human thyroperoxidase in the endoplasmic reticulum involves two different pathways depending on the folding state of the protein.
Topics: Acetylcysteine; Ammonium Chloride; Animals; Antibodies, Monoclonal; Chloroquine; CHO Cells; Cricetinae; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Emetine; Endoplasmic Reticulum; Humans; Multienzyme Complexes; Peroxidase; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Folding; Thyroid Gland | 2000 |
Cellular processing of a multibranched lysine core with tumor antigen peptides and presentation of peptide epitopes recognized by cytotoxic T lymphocytes on antigen-presenting cells.
Topics: Animals; Antigen Presentation; Antigen-Presenting Cells; Antigens, Neoplasm; Brefeldin A; Chloroquine; Cycloheximide; Epitopes, T-Lymphocyte; Female; Mice; Mice, Inbred BALB C; Microscopy, Confocal; T-Lymphocytes, Cytotoxic | 2002 |
pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes.
Topics: Amino Acid Sequence; Androstadienes; Animals; Biological Transport; Brefeldin A; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Cells, Cultured; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cycloheximide; Cytosol; Endosomes; Enzyme Inhibitors; Hepatocytes; Hydrogen-Ion Concentration; Liver Neoplasms; Metabolism; Molecular Sequence Data; Nocodazole; Protein Synthesis Inhibitors; Rats; Recombinant Proteins; Time Factors; Wortmannin | 2003 |
The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs.
Topics: Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Cycloheximide; Drug Resistance, Multiple, Fungal; Gene Deletion; Genes, Fungal; Mefloquine; Mutation; Quinacrine; Quinidine; Quinine; Saccharomyces cerevisiae; Transcription, Genetic | 2004 |
Janus kinase 2 enhances the stability of the mature growth hormone receptor.
Topics: Ammonium Chloride; Cell Line, Tumor; Chloroquine; Cycloheximide; Drug Stability; Human Growth Hormone; Humans; Janus Kinase 2; Lactones; Lysosomes; Molecular Conformation; Proteasome Inhibitors; Protein Synthesis Inhibitors; Protein Transport; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Somatotropin; RNA Interference; Signal Transduction; Tissue Distribution | 2005 |
Multilevel regulation of leptin storage, turnover, and secretion by feeding and insulin in rat adipose tissue.
Topics: Adipocytes; Adipose Tissue; Animals; Blotting, Northern; Body Weight; Chloroquine; Cycloheximide; Insulin; Iodine Isotopes; Leptin; Leupeptins; Lysosomes; Male; Rats; Rats, Wistar; RNA, Messenger; Starvation; Sulfur Isotopes | 2006 |
Determinants of growth hormone receptor down-regulation.
Topics: Acetylcysteine; Animals; Cell Line; Chloroquine; Cycloheximide; Down-Regulation; Human Growth Hormone; Humans; Janus Kinase 2; Lysosomes; Mice; Mutation; Phosphorylation; Proteasome Inhibitors; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Rabbits; Receptors, Somatotropin; Recombinant Proteins; Transfection; Tyrosine | 2007 |
Viral protein synthesis is required for Enterovirus 71 to induce apoptosis in human glioblastoma cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Chlorocebus aethiops; Chloroquine; Cycloheximide; DNA Fragmentation; Enterovirus A, Human; Glioblastoma; Guanidine; Humans; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Ultraviolet Rays; Vero Cells; Viral Proteins; Virus Replication | 2008 |
Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.
Topics: Amino Acid Transport System A; Amino Acid Transport Systems; Amino Acids; Androstadienes; Animals; Anthracenes; Cell Line; Chloroquine; Cycloheximide; Dactinomycin; Flavonoids; Insulin; Insulin Antagonists; Muscle, Skeletal; Osmotic Pressure; Protein Synthesis Inhibitors; Rats; Up-Regulation; Wortmannin | 2009 |
Insulin inhibits Abeta fibrillogenesis through a decrease of the GM1 ganglioside-rich microdomain in neuronal membranes.
Topics: Actins; Amyloid beta-Peptides; Animals; Blotting, Western; Cell Membrane; Chloroquine; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; G(M1) Ganglioside; Homeostasis; Hypoglycemic Agents; Insulin; Liposomes; Morpholines; Neurofibrillary Tangles; Neurons; PC12 Cells; Phosphatidylinositol 3-Kinases; Protein Synthesis Inhibitors; Rats | 2010 |
Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease.
Topics: Adaptor Proteins, Vesicular Transport; Amino Acids; Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Antibodies, Monoclonal; Aspartic Acid Endopeptidases; Caspase 3; Cell Death; Cell Membrane; Cells, Cultured; Chloroquine; Cycloheximide; Dendritic Spines; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Lysosomes; Male; Membrane Proteins; Mice; Neurons; Neuropeptides; Oligonucleotides; Protein Synthesis Inhibitors; Rats; Transfection | 2012 |
Synergism of antimalarial antibiotics with hydrogen peroxide in inhibiting Plasmodium falciparum growth in culture.
Topics: Anti-Bacterial Agents; Antimalarials; Chloramphenicol; Chloroquine; Cycloheximide; Drug Resistance; Drug Synergism; Hydrogen Peroxide; Oxidants; Plasmodium falciparum; Tetracycline | 2014 |
A Regulated, Ubiquitin-Independent Degron in IκBα.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Ankyrin Repeat; Cell Line; Chloroquine; Cycloheximide; DNA-Binding Proteins; Green Fluorescent Proteins; HEK293 Cells; Humans; I-kappa B Proteins; Lysosomes; Macrolides; Mice; NF-KappaB Inhibitor alpha; Proteolysis; Signal Transduction; Transcription Factor RelA; Ubiquitin | 2015 |
Estrogen receptor-related receptor γ regulates testicular steroidogenesis through direct and indirect regulation of steroidogenic gene expression.
Topics: Analysis of Variance; Animals; Chloroquine; Cyclic AMP; Cycloheximide; Gene Expression; Gene Expression Regulation; HEK293 Cells; Humans; Leydig Cells; Male; Mice; Mice, Inbred C57BL; Nuclear Receptor Subfamily 4, Group A, Member 1; Phosphoproteins; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Receptors, Estrogen; RNA, Messenger; Sequence Deletion; Steroid 17-alpha-Hydroxylase; Testosterone | 2017 |