chloroquine has been researched along with colchicine in 140 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 77 (55.00) | 18.7374 |
| 1990's | 34 (24.29) | 18.2507 |
| 2000's | 17 (12.14) | 29.6817 |
| 2010's | 12 (8.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Farasati, NA; Huang, Y; Randhawa, P | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chabot, GG; Deguin, B; Dumontet, V; Espindola, LS; Grellier, P; Grougnet, R; Mai, LH; Michel, S; Poulain, C; Quentin, L; Vo, HT | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Clauser, H; Djiane, J; Houdebine, LM | 1 |
| Florén, CH; Nilsson, A | 3 |
| Ostlund, RE; Pfleger, B; Schonfeld, G | 1 |
| Floman, Y | 1 |
| Chang, H; Kobayashi, M; Olefsky, JM | 1 |
| Mørland, B | 2 |
| Chu, LL; Cohn, DV; MacGregor, RR | 1 |
| Burkholder, DE; Maynard, JR; Pizzuti, DJ | 1 |
| Govaerts-Lepicard, M | 1 |
| Eidinger, D; Gery, I | 1 |
| Chajek, T; Friedman, G; Stein, O; Stein, Y | 1 |
| Florén, CH; Nilsson, A; Nordgren, H | 1 |
| Kameyama, T; Mukaide, A | 1 |
| Fintel, DJ; Maynard, JR; Nemerson, Y; Pitlick, FA | 1 |
| Florén, CH; Liao, W | 1 |
| Barluzzi, R; Bistoni, F; Blasi, E; Mazzolla, R; Mosci, P | 1 |
| Kramer, TT; Roof, MB; Roth, JA | 1 |
| Spear, PG; Wittels, M | 1 |
| Altar, CA; Baudry, M | 1 |
| Lear, MC; McAbee, DD; Weigel, PH | 1 |
| Marinelli, RA; Rodríguez Garay, EA; Roma, MG | 1 |
| Meryman, HT; Mincheff, MS | 1 |
| Blomgren, K; Thyberg, J | 1 |
| Clarke, BL; McAbee, DD; Oka, JA; Weigel, PH | 1 |
| Gordon, AH; Hart, PD; Young, MR | 1 |
| Odum, L; Rehfeld, JF | 1 |
| Giulian, D; Robertson, C | 1 |
| Blomhoff, JP; Letnes, H; Stray, N | 1 |
| Derksen, JT; Dijkstra, J; Roerdink, FH; Scherphof, GL; Spanjer, HH | 1 |
| Blomhoff, JP; Drevon, CA; Nossen, JO; Rustan, AC | 1 |
| Knecht, TP; Pittman, RC; Rosenbaum, MS; Taylor, CA | 1 |
| Chen, J; George, JK; Giulian, D; Ingeman, JE; Noponen, M | 1 |
| Clarke, BL; Weigel, PH | 1 |
| Gliemann, J; Sonne, O | 1 |
| Bjørneboe, A; Bjørneboe, GE; Drevon, CA; Hagen, BF; Nossen, JO | 1 |
| Charlwood, PA; Chindemi, PA; Regoeczi, E | 1 |
| Beck, WT; Cirtain, MC; Danks, MK; Felsted, RL; Safa, AR; Suttle, DP; Trent, JM; Wolverton, JS | 1 |
| Alaupovic, P; Dashti, N; Wolfbauer, G | 1 |
| Dashti, N; Wolfbauer, G | 1 |
| Austgulen, R; Kildahl-Andersen, O; Nissen-Meyer, J | 1 |
| Finbloom, DS | 1 |
| Morgan, EH; Sorokin, LM; Yeoh, GC | 1 |
| Lake, JR; Licko, V; Renner, EL; Scharschmidt, BF; Van Dyke, RW | 1 |
| Bergeron, JJ; Guyda, HJ; Lai, WH | 1 |
| Cooper, EL; Ghoneum, M; Smith, C | 1 |
| Djiane, J; Ferland, LH; Houdebine, LM; Kelly, PA; Rosa, AA | 1 |
| Damerau, B; Roesler, J; Vogt, W | 1 |
| Tiess, D | 1 |
| Alberto, R; Lyman, M; May, CD | 1 |
| Dukor, P; Weissmann, G; Zurier, RB | 1 |
| Hawkins, D | 1 |
| Chinea, G; Oronsky, AL; Perper, RJ; Sanda, M | 1 |
| Hegner, D | 1 |
| Hochschild, R | 1 |
| Ignarro, LJ | 1 |
| Paparopoli, G; Sciarrino, E | 1 |
| Howells, RE; Peters, W; Robinson, BL; Warhurst, DC | 1 |
| Datko, LJ; Kassarich, J; Rosenthale, ME; Schneider, F | 1 |
| Join, F; Tremblay, F | 1 |
| Fellman, M; Weimar, V | 1 |
| Chang, TM; Kullberg, DW | 1 |
| Berg, T; Tolleshaug, H | 1 |
| Berg, T; Bleken, A; Tolleshaug, H; Torjesen, P | 1 |
| Djiane, J; Houdebine, LM | 1 |
| Djiane, J; Houdebine, LM; Kelly, PA | 1 |
| DiSorbo, DM; Litwack, G; Moriarity, DM; Savage, CR | 1 |
| Attie, AD; Pittman, RC; Steinberg, D; Watanabe, Y | 1 |
| Baglioni, C; Branca, AA; D'Alessandro, SB; Faltynek, CR | 1 |
| Djiane, J; Gandilhon, F; Gandilhon, P; Kelly, PA; Melancon, R | 1 |
| Hansson, HA; Lange, S; Lönnroth, I; Rozell, B; Tinberg, H | 1 |
| Alaupovic, P; Dashti, N; Knowles, B; Koren, E; Wolfbauer, G | 1 |
| Bystryn, JC; Johnston, D | 1 |
| Gall, EP | 1 |
| Aubery, M; Codogno, P; Goussault, Y; Hornebeck, W; Robert, L | 1 |
| Goodman, HM; Gorin, E; Grichting, G | 1 |
| Lazarus, NR; O'Connor, KJ; Pogson, CI; Poole, GP | 1 |
| Andersson, A; Lantz, E | 1 |
| Baldeschwieler, JD; Tin, GW; Wu, PS | 1 |
| Darrow, RM; Nafz, MA; Varandani, PT | 1 |
| Crichton, RR; Hoffmann, P; Octave, JN; Schneider, YJ; Trouet, A | 1 |
| Kovács, AL; Seglen, PO | 1 |
| Eady, RP; Hallam, C; Pritchard, DI; Trigg, S | 1 |
| Brouwer, A; Knook, DL | 1 |
| Berg, T; Norum, KR; Ose, L; Røken, I | 1 |
| Brady, RO; Kusiak, JW; Quirk, JM | 1 |
| Chu, F; Cowman, AF; Gros, P; Karcz, S; Schurr, E; van Es, HH; Vidal, S | 1 |
| Bunnett, NW; Garland, AM; Grady, EF; Payan, DG; Vigna, SR | 1 |
| Harada, M; Itano, S; Mimura, Y; Noguchi, K; Ohishi, M; Sakisaka, S; Sata, M; Shakado, S; Yoshida, H; Yoshitake, M | 1 |
| Axelrod, JH; Baru, M; Nur, I | 1 |
| Broeks, A; Calafat, J; Janssen, HW; Plasterk, RH | 1 |
| Jiménez, E; Montiel, M; Vinson, GP | 1 |
| Albert, MJ; Ansaruzzaman, M; Bhuiyan, NA; Faruque, AS; Neogi, PK | 1 |
| DelValle, J; Kokudo, N; Kothary, PC; Raper, SE | 1 |
| Dash, PK; Moore, AN | 1 |
| Antohe, F; Dobrila, L; Heltianu, C; Simionescu, M; Simionescu, N | 1 |
| Barluzzi, R; Bistoni, F; Blasi, E; Mazzolla, R | 1 |
| Hirata, K; Ikeda, H; Kikuchi, K; Ohta, M; Sato, N; Takahashi, S; Ueda, D; Wada, Y | 1 |
| Khan, MA | 1 |
| Balkenende, AY; Slaper-Cortenbach, IC; van den Berg, H; van der Schoot, CE; Van Leeuwen, EF; Vervoordeldonk, SF; von dem Borne, AE | 1 |
| Holmin, S; Mathiesen, T | 1 |
| Morinelli, TA; Ullian, ME; Walsh, LG | 1 |
| Guan, X; Ruch, RJ | 1 |
| Dayer, JM; Galve-de Rochemonteix, B; Nicod, LP | 1 |
| Barnes, K; Turner, AJ | 1 |
| Arondelle, C; Broucker De, T; Margent, P; Tattevin, P | 1 |
| Bang, KW; Blanchette, VS; Freedman, J; Semple, JW; Speck, ER | 1 |
| Bertsch, T; Fassbender, K; Fatar, M; Hennerici, M; Kischka, U; Kühl, S; Ragoschke, A; Schlueter, D; Schneider, S | 1 |
| Hu, Gf; Kim, Hj; Riordan, JF; Xu, Cj | 1 |
| Guéant, J; Guy, M; Hatier, R; Lambert, D; Pons, L | 1 |
| Cho, KM; Han, DJ; Kim, SC; Park, HY; We, YM | 1 |
| Lindblom, TH; Pierce, GJ; Sluder, AE | 1 |
| BOUMA, HG; DEVRIES, K; JANSZ, A; NIEWEG, HO | 1 |
| ASCHHEIM, E; EDDY, DD; FARBER, EM | 1 |
| ROOK, A | 1 |
| Chen, J; Chen, L; Huang, Y; Li, G; Lu, D; Lu, J; Wu, H; Zhang, J | 1 |
| Brownell, I; Franks, AG; Soter, NA | 1 |
| Khan, DA; Morgan, M | 1 |
| Kikuchi, H; Oite, T; Serikawa, T; Tanaka, K | 1 |
| Ju, JS; Miller, SE; Varadhachary, AS; Weihl, CC | 1 |
3 review(s) available for chloroquine and colchicine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Effects of myotoxins on skeletal muscle fibers.
Topics: Chloroquine; Cholinesterase Inhibitors; Colchicine; Drug-Related Side Effects and Adverse Reactions; Muscle Fibers, Skeletal; Muscle, Skeletal; Vincristine | 1995 |
Therapeutic alternatives for chronic urticaria: an evidence-based review, part 1.
Topics: Calcineurin Inhibitors; Chloroquine; Colchicine; Histamine Antagonists; Humans; Leukotriene Antagonists; Mycophenolic Acid; Prednisone; Sulfones; Urticaria | 2008 |
137 other study(ies) available for chloroquine and colchicine
| Article | Year |
|---|---|
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.
Topics: Antiviral Agents; BK Virus; Cell Line; Chloroquine; Humans; Microbial Sensitivity Tests; Molecular Structure; Nystatin; Virus Replication | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Antivascular and anti-parasite activities of natural and hemisynthetic flavonoids from New Caledonian Gardenia species (Rubiaceae).
Topics: Angiogenesis Inhibitors; Animals; Antiparasitic Agents; Cell Line, Tumor; Cell Survival; Drug Design; Flavonoids; Flowers; Gardenia; Humans; Leishmania; Molecular Structure; New Caledonia; Plant Extracts; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei gambiense | 2015 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
[Role of lysosomes, microtubules and microfilaments in the mechanism of the lactogenic action of prolactin in the rabbit mammary gland].
Topics: Ammonium Chloride; Animals; Caseins; Cattle; Chloroquine; Colchicine; Cytochalasin B; Cytoskeleton; Female; In Vitro Techniques; Lactation; Lysosomes; Mammary Glands, Animal; Microtubules; Pregnancy; Prolactin; Pseudopregnancy; Rabbits | 1979 |
Binding, interiorization and degradation of cholesteryl ester-labelled chylomicron-remmant particles by rat hepatocyte monolayers.
Topics: Animals; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Chylomicrons; Colchicine; Kinetics; Lipoproteins, HDL; Lipoproteins, VLDL; Liver; Male; Rats | 1977 |
Role of microtubules in low density lipoprotein processing by cultured cells.
Topics: Cells, Cultured; Chloroquine; Colchicine; Cytochalasins; Endocytosis; Lipoproteins, LDL; Lysosomes; Microtubules; Subcellular Fractions | 1979 |
Prostaglandin E production by cultured inflamed rat synovium; stimulation by colchicine and inhibition by chloroquine.
Topics: Animals; Arachidonic Acids; Arthritis; Cell-Free System; Chloroquine; Colchicine; Corticosterone; Culture Techniques; Dexamethasone; Male; Prostaglandins E; Rats; Streptococcus pyogenes; Synovitis | 1978 |
Interactions between insulin and its receptors after the initial binding event. Functional heterogeneity and relationships to insulin degradation.
Topics: Adipose Tissue; Animals; Cell Membrane; Chloroquine; Colchicine; Cytochalasin B; Deoxyglucose; Dinitrophenols; In Vitro Techniques; Insulin; Kinetics; Male; Protein Binding; Rats; Receptor, Insulin | 1979 |
Studies on selective induction of lysosomal enzyme activities in mouse peritoneal macrophages.
Topics: Acid Phosphatase; Animals; Cathepsins; Cell Membrane; Chloroquine; Colchicine; Culture Media; Cycloheximide; Cytochalasin B; Dactinomycin; Endocytosis; Endotoxins; Glucuronidase; L-Lactate Dehydrogenase; Latex; Lysosomes; Macrophages; Mice; Microspheres; Subcellular Fractions; Trypsin | 1979 |
Energy-dependent intracellular translocation of proparathormone.
Topics: Anaerobiosis; Animals; Antimycin A; Cattle; Chloroquine; Colchicine; Cycloheximide; Cytochalasin B; Deoxyglucose; Deuterium; Dinitrophenols; In Vitro Techniques; Kinetics; Oligomycins; Parathyroid Glands; Parathyroid Hormone; Rotenone; Temperature; Tromethamine; Vinblastine | 1977 |
Comparative pharmacologic effects on tissue factor activity in normal cells and an established cell line.
Topics: Amnion; Butyrates; Cell Line; Cells, Cultured; Chloroquine; Colchicine; Endothelium; Fibroblasts; HeLa Cells; Humans; Hydrocortisone; Male; Muscle, Smooth; Nucleotides, Cyclic; Penis; Thromboplastin; Umbilical Veins; Vinblastine | 1978 |
Uptake and degradation of iodine-labelled chylomicron remnant particles by monolayers of rat hepatocytes.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Chylomicrons; Colchicine; Concanavalin A; Electrophoresis, Polyacrylamide Gel; Lipid Metabolism; Liver; Male; Proteins; Rats | 1978 |
[Seriousness factors in acute poisoning].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Belgium; Child; Child, Preschool; Chloroquine; Colchicine; Diphenoxylate; Environmental Exposure; Female; Humans; Infant; Loperamide; Male; Medication Errors; Middle Aged; Poison Control Centers; Poisoning; Suicide, Attempted | 1978 |
Degradation of chylomicron remnant cholesteryl ester by rat hepatocyte monolayers. Inhibition by chloroquine and colchicine.
Topics: Animals; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Chylomicrons; Colchicine; Cycloheximide; Kinetics; Liver; Male; Rats | 1977 |
Selective and opposing effects of cytochalasin B and other drugs on lymphocyte responses to different doses of mitogens.
Topics: Animals; Cell Adhesion; Chloroquine; Chlorpromazine; Colchicine; Concanavalin A; Cytochalasin B; Dose-Response Relationship, Immunologic; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred CBA; Mitogens; Time Factors | 1977 |
Effect of colchicine, cycloheximide and chloroquine on the hepatic triacylglycerol hydrolase in the intact rat and perfused liver.
Topics: Animals; Chloroquine; Colchicine; Cycloheximide; Half-Life; Heparin; Kinetics; Lipase; Liver; Male; Perfusion; Rats; Triglycerides | 1977 |
Effects of chloroquine and colchicine on the degradation of chyle cholesteryl ester and phospholipids in vivo.
Topics: Animals; Cell Membrane; Chloroquine; Cholesterol Esters; Chyle; Colchicine; Dose-Response Relationship, Drug; Liver; Male; Microscopy, Electron; Phospholipids; Rats; Subcellular Fractions | 1977 |
[Effects of drugs on leukocyte migration].
Topics: Animals; Chemotaxis; Chloroquine; Colchicine; Cytochalasin B; Hydrocortisone; In Vitro Techniques; Leukocytes; Neutrophils; Nucleotides, Cyclic; Rabbits | 1976 |
Tissue factor in cultured cells: pharmacologic effects.
Topics: Amnion; Cell Line; Cell Membrane; Cells, Cultured; Chloroquine; Colchicine; Dimethyl Sulfoxide; Glucocorticoids; Humans; In Vitro Techniques; Nucleotides, Cyclic; Ouabain; Thromboplastin; Vinblastine | 1976 |
Polymyxin B enhances low density lipoprotein catabolism in hepatic and extrahepatic cells.
Topics: Animals; Calcium; Carcinoma, Hepatocellular; Cattle; Cells, Cultured; Chloroquine; Colchicine; Endothelium, Vascular; Fibroblasts; Humans; Lipoproteins, LDL; Liver; Liver Neoplasms; Muscle, Smooth; Polymyxin B; Pronase; Receptors, LDL; Tumor Cells, Cultured; Type C Phospholipases | 1992 |
Experimental model of intracerebral infection with Cryptococcus neoformans: roles of phagocytes and opsonization.
Topics: Animals; Brain Diseases; Chloroquine; Colchicine; Cryptococcosis; Disease Models, Animal; Female; Mice; Opsonin Proteins; Phagocytes; Phagocytosis | 1992 |
A comparison of virulent and avirulent strains of Salmonella choleraesuis and their ability to invade Vero cell monolayers.
Topics: Actin Cytoskeleton; Animals; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Blotting, Western; Chloroquine; Chromatography, Affinity; Colchicine; Cytochalasins; Electrophoresis, Polyacrylamide Gel; Lethal Dose 50; Mannose; Mice; Microtubules; Salmonella; Trypsin; Vero Cells; Virulence | 1992 |
Penetration of cells by herpes simplex virus does not require a low pH-dependent endocytic pathway.
Topics: Adsorption; Amantadine; Animals; Chloroquine; Colchicine; Concanavalin A; Cytochalasin B; Dithiothreitol; Endocytosis; Heparin; Hydrogen-Ion Concentration; Microscopy, Electron; Monensin; Simplexvirus; Trifluoperazine; Tumor Cells, Cultured; Vero Cells; Vesicular stomatitis Indiana virus; Viral Plaque Assay; Wheat Germ Agglutinins | 1991 |
Entorhinal cortex lesion or intrahippocampal colchicine injection increases peripheral type benzodiazepine binding sites in rat hippocampus.
Topics: Animals; Autoradiography; Benzodiazepinones; Cerebral Ventricles; Chloroquine; Colchicine; Hippocampus; Injections, Intraventricular; Isoquinolines; Male; Microinjections; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium | 1991 |
Total cellular activity and distribution of a subpopulation of galactosyl receptors in isolated rat hepatocytes are differentially affected by microtubule drugs, monensin, low temperature, and chloroquine.
Topics: Animals; Asialoglycoproteins; Cells, Cultured; Chloroquine; Colchicine; Galactose; Kinetics; Liver; Male; Microtubules; Monensin; Orosomucoid; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Temperature | 1991 |
Biliary excretion of polyethylene glycol molecular weight 900. Evidence for a bile salt-stimulated vesicular transport mechanism.
Topics: Animals; Bile; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Chloroquine; Colchicine; Dehydrocholic Acid; Liver; Male; Molecular Weight; Polyethylene Glycols; Rats; Rats, Inbred Strains; Sucrose; Umbelliferones; Vinblastine | 1991 |
Costimulatory signals necessary for induction of T cell proliferation.
Topics: Antigen-Presenting Cells; Cell Adhesion Molecules; Chloroquine; Colchicine; Concanavalin A; Fixatives; Formaldehyde; Glycosylation; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-6; Lymphocyte Activation; Polymers; Protein Biosynthesis; T-Lymphocytes | 1990 |
Phenotype modulation in primary cultures of rat aortic smooth muscle cells. Effects of drugs that interfere with the functions of the vacuolar system and the cytoskeleton.
Topics: Animals; Aorta; Cell Adhesion; Cell Survival; Cells, Cultured; Chloroquine; Colchicine; Cytochalasins; Cytoskeleton; Male; Microtubules; Monensin; Muscle Development; Muscle, Smooth, Vascular; Nocodazole; Organ Specificity; Rats; Rats, Inbred Strains | 1990 |
The surface activity of the same subpopulation of galactosyl receptors on isolated rat hepatocytes is modulated by colchicine, monensin, ATP depletion, and chloroquine.
Topics: Adenosine Triphosphate; Animals; Asialoglycoproteins; Chloroquine; Colchicine; Endocytosis; In Vitro Techniques; Kinetics; Liver; Monensin; Orosomucoid; Rats; Receptors, Cell Surface | 1990 |
Tubular lysosomes and their drug reactivity in cultured resident macrophages and in cell-free medium.
Topics: Ammonium Chloride; Animals; Cell-Free System; Cells, Cultured; Chloroquine; Colchicine; Culture Media; Female; Lysosomes; Macrophages; Mice; Microscopy, Fluorescence; Microtubules; Nocodazole; Tetradecanoylphorbol Acetate | 1990 |
Expression and processing of procholecystokinin in a rat medullary thyroid carcinoma cell line.
Topics: Animals; Carcinoma; Chloroquine; Cholecystokinin; Chromatography, Gel; Colchicine; Dexamethasone; Gene Expression; Glycine; Monensin; Peptide Fragments; Protein Precursors; Protein Processing, Post-Translational; Rats; Sincalide; Sulfates; Thyroid Neoplasms; Tumor Cells, Cultured | 1990 |
Inhibition of mononuclear phagocytes reduces ischemic injury in the spinal cord.
Topics: Animals; Chloroquine; Colchicine; Dexamethasone; Evoked Potentials, Somatosensory; Ischemia; Phagocytes; Rabbits; Spinal Cord; Spinal Cord Injuries | 1990 |
Intracellular regulation of lipoprotein lipase in human monocyte-derived macrophages.
Topics: Cell Differentiation; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Humans; In Vitro Techniques; Lipoprotein Lipase; Macrophages; Monensin; Monocytes; Secretory Rate; Tunicamycin | 1990 |
Uptake and intracellular processing of targeted and nontargeted liposomes by rat Kupffer cells in vivo and in vitro.
Topics: alpha-Fetoproteins; Animals; Asialoglycoproteins; Cells, Cultured; Chloroquine; Colchicine; Cytochalasins; Endocytosis; Fetuins; Hexosamines; Kupffer Cells; Lactosylceramides; Liposomes; Lysosomes; Membrane Lipids; Metabolic Clearance Rate; Monensin; Phosphatidylcholines; Rats; Sphingomyelins; Structure-Activity Relationship; Trifluoperazine | 1985 |
Release of hepatic lipase and very low density lipoprotein by cultured rat hepatocytes.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Chloroquine; Colchicine; Cycloheximide; Dextrans; Heparin; Lipase; Lipoproteins, VLDL; Liver; Oleic Acid; Oleic Acids; Rats | 1986 |
A nonendocytotic mechanism for the selective uptake of high density lipoprotein-associated cholesterol esters.
Topics: Adrenal Cortex Neoplasms; alpha-Fetoproteins; Animals; Apolipoprotein A-I; Apolipoproteins A; Asialoglycoproteins; Azides; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Colchicine; Fetuins; Fibroblasts; Heparin; Humans; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Liver Neoplasms; Mice; Monensin; Pinocytosis; Rats; Sodium Azide | 1987 |
The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain.
Topics: Animals; Astrocytes; Brain Injuries; Cerebral Cortex; Chloroquine; Colchicine; Dexamethasone; Encephalitis; Gliosis; Microspheres; Neovascularization, Pathologic; Phagocytes; Rats; Rats, Inbred Strains; Wound Healing; Wounds, Penetrating | 1989 |
Differential effects of leupeptin, monensin and colchicine on ligand degradation mediated by the two asialoglycoprotein receptor pathways in isolated rat hepatocytes.
Topics: Animals; Asialoglycoproteins; Cells, Cultured; Chloroquine; Colchicine; Dose-Response Relationship, Drug; Galactose; Leupeptins; Liver; Male; Monensin; Oligopeptides; Orosomucoid; Rats; Rats, Inbred Strains; Receptors, Cell Surface | 1989 |
Uptake and degradation of insulin and alpha 2-macroglobulin-trypsin complex in rat adipocytes. Evidence for different pathways.
Topics: Adipose Tissue; alpha-Macroglobulins; Amines; Animals; Biological Transport, Active; Chloroquine; Colchicine; Epididymis; In Vitro Techniques; Insulin; Male; Rats; Rats, Inbred Strains; Trypsin | 1985 |
Secretion of alpha-tocopherol from cultured rat hepatocytes.
Topics: Animals; Cells, Cultured; Chloroquine; Colchicine; Eicosapentaenoic Acid; Kinetics; Liver; Male; Monensin; Oleic Acid; Oleic Acids; Perfusion; Rats; Rats, Inbred Strains; Vitamin E | 1987 |
The effects of cytotropic compounds on the resialylation of human asialotransferrin type 3 in the rat.
Topics: Alkaloids; Animals; Asialoglycoproteins; Chloroquine; Colchicine; Female; Humans; Leupeptins; Liver; Lysine; Male; Microtubules; Paclitaxel; Protein Biosynthesis; Rats; Starvation; Transferrin; Vinblastine | 1985 |
Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Chromosome Banding; Chromosomes, Human, Pair 13; Colchicine; Dactinomycin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia; Membrane Glycoproteins; Molecular Weight; Podophyllotoxin; Teniposide; Tumor Cells, Cultured; Verapamil; Vinblastine; Vinca Alkaloids | 1987 |
Binding and degradation of human high-density lipoproteins by human hepatoma cell line HepG2.
Topics: Binding Sites; Carcinoma, Hepatocellular; Cell Line; Chemical Phenomena; Chemistry; Chloroquine; Cholesterol; Colchicine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Liver Neoplasms; Substrate Specificity | 1985 |
Studies on the binding and degradation of human very-low-density lipoproteins by human hepatoma cell line HepG2.
Topics: Apolipoproteins B; Apolipoproteins E; Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Cholesterol Esters; Colchicine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Liver Neoplasms; Lysosomes; Protein Binding; Receptors, LDL; Sterols | 1986 |
Human monocyte-released cytotoxic factor: effect on various cellular functions, and dependency of cytolysis on various metabolic processes.
Topics: Adenosine Triphosphate; Cell Survival; Chloroquine; Colchicine; Cycloheximide; Cytotoxicity, Immunologic; Cytotoxins; Dactinomycin; Humans; Mitomycin; Mitomycins; Monocytes; Nucleic Acids; Protein Biosynthesis; Ricin; Uncoupling Agents | 1986 |
Internalization and degradation of human recombinant interferon-gamma in the human histiocytic lymphoma cell line, U937: relationship to Fc receptor enhancement and antiproliferation.
Topics: Cell Line; Chloroquine; Colchicine; Cytochalasin B; Endocytosis; Humans; In Vitro Techniques; Interferon-gamma; Monensin; Monocytes; Receptors, Fc; Recombinant Proteins; Time Factors | 1988 |
Transferrin endocytosis and iron uptake in developing myogenic cells in culture: effects of microtubular and metabolic inhibitors, sulphydryl reagents and lysosomotrophic agents.
Topics: 2,4-Dinitrophenol; Ammonium Chloride; Animals; Antimycin A; Azides; Cells, Cultured; Chick Embryo; Chloroquine; Colchicine; Dinitrophenols; Endocytosis; Iron; Methylamines; Muscles; Podophyllotoxin; Sodium Azide; Sulfhydryl Reagents; Transferrin; Vinblastine | 1988 |
Fluid phase endocytosis by cultured rat hepatocytes and perfused rat liver: implications for plasma membrane turnover and vesicular trafficking of fluid phase markers.
Topics: Animals; Cell Membrane; Cells, Cultured; Chloroquine; Colchicine; Endocytosis; Exocytosis; Extracellular Space; Inulin; Kinetics; Liver; Perfusion; Rats; Taurocholic Acid | 1986 |
Binding and internalization of epidermal growth factor in human term placental cells in culture.
Topics: 3-O-Methylglucose; Bacitracin; Cells, Cultured; Chloroquine; Colchicine; Epidermal Growth Factor; Female; Humans; Kinetics; Methylglucosides; Microscopy, Electron; Microvilli; Placenta; Pregnancy; Trophoblasts | 1986 |
Inhibition of SK cell activity in frogs by certain drugs and sugars.
Topics: Animals; Carbohydrates; Cell Line; Chloroquine; Colchicine; Cycloheximide; Cytotoxicity, Immunologic; Erythrocytes; Female; Humans; Killer Cells, Natural; Male; Neoplasms, Experimental; Rana pipiens | 1987 |
Cytotoxic activity of stimulated mouse macrophages exposed to various inhibitors.
Topics: Animals; Carbon Radioisotopes; Cell Line; Chloroquine; Colchicine; Cytotoxicity, Immunologic; Lysosomes; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Monensin; Neoplasms, Experimental; Peritoneal Cavity; Zymosan | 1986 |
Maintenance of prolactin (PRL) binding sites in rat liver cells in suspension culture: effect of PRL and of inhibitors of various cellular functions.
Topics: Animals; Binding Sites; Cells, Cultured; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Dinitrophenols; Female; Histological Techniques; Liver; Prolactin; Rats | 1985 |
Pharmacological characterization of the slow component of deactivation of guinea-pig isolated ileum to the spasmogenic action of C5adesArg.
Topics: Animals; Chloroquine; Colchicine; Complement C5; Complement C5a, des-Arginine; Cycloheximide; Cytochalasin B; Guinea Pigs; Ileum; In Vitro Techniques; Lumicolchicines; Muscle Contraction; Muscle, Smooth; Vinblastine | 1985 |
[Rapid UV-spectrophotometric determination of toxic materials in samples of stomach contents, with special reference to the relatively less common organic poisons].
Topics: Adult; Aged; Anticonvulsants; Barbiturates; Benzalkonium Compounds; Chemistry, Clinical; Chloroquine; Cholinesterase Inhibitors; Colchicine; Forensic Medicine; Humans; Isoniazid; Methaqualone; Middle Aged; Niacinamide; Nicotine; Oils; Poisons; Promazine; Pyridines; Spectrophotometry; Stomach; Ultraviolet Rays | 1969 |
Effects of compounds which inhibit lymphocyte stimulation on the utilization of glucose by leukocytes.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Carbon Isotopes; Chloroquine; Colchicine; Culture Media; Culture Techniques; Ethanol; Glucose; Humans; Hydrocortisone; Lectins; Leukocytes; Lymphocyte Activation; Lymphocytes; Niacinamide; Ouabain; Theophylline; Time Factors; Tritium | 1970 |
Effect of cyclic AMP on release of lysosomal enzymes from phagocytes.
Topics: Adenine Nucleotides; Amidohydrolases; Animals; Cathepsins; Chloroquine; Colchicine; Culture Techniques; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dimethyl Sulfoxide; Glucuronidase; Humans; Hydrolases; L-Lactate Dehydrogenase; Leukocytes; Lysosomes; Macrophages; Mice; Phagocytosis; Prostaglandins; Stimulation, Chemical; Sulfatases; Theophylline; Vinblastine; Zymosan | 1971 |
Neutrophilic leukocytes in immunologic reactions in vitro. 3. Pharmacologic modulation of lysosomal constituent release.
Topics: Animals; Bucladesine; Chloroquine; Colchicine; Collagen; Epinephrine; Ethylmaleimide; Exocytosis; Ferritins; Glucose; Hydrocortisone; Iodoacetates; Isoproterenol; Latex; Lysosomes; Membranes; Microspheres; Models, Biological; Neutrophils; Phagocytosis; Phenylephrine; Propranolol; Rabbits; Salicylates; Theophylline; Vinblastine | 1974 |
Leukocyte chemotaxis in vivo. II. Analysis of the selective inhibition of neutrophil or mononuclear cell accumulation.
Topics: Animals; Bucladesine; Carrageenan; Chemotaxis; Chloroquine; Chlorpromazine; Chromium Radioisotopes; Clonidine; Colchicine; Cyclophosphamide; Female; Flufenamic Acid; Indomethacin; Inflammation; Leukocyte Transfusion; Leukocytes; Methylprednisolone; Monocytes; Neutrophils; Phenylbutazone; Rats; Transplantation, Homologous; Venoms; Vinblastine | 1974 |
[Protective effect of different drugs on the membrane of isolated granules from polymorphonuclear leukocytes of cattle. (The modification of lysophosphate conditioned granulysis)].
Topics: Acid Phosphatase; Animals; Anti-Inflammatory Agents; Cattle; Cell Membrane; Chloroquine; Colchicine; Glucocorticoids; Histamine H1 Antagonists; In Vitro Techniques; Leukocytes; Lysophosphatidylcholines; Lysosomes; Microscopy, Electron; Peptides; Phenothiazines; Phospholipases; Pyrazoles; Salicylates | 1969 |
Effect of membrane stabilizing drugs on mortality in Drosophila melanogaster.
Topics: Adrenal Cortex Hormones; Aging; Analgesics; Animals; Cell Membrane; Central Nervous System Stimulants; Chloroquine; Colchicine; Drosophila; Female; Histamine H1 Antagonists; Inositol; Life Expectancy; Lysosomes; Male; Meclofenoxate; Membranes; Pantothenic Acid; Phenothiazines; Povidone; Procaine; Salicylates | 1971 |
Release of neutral protease and beta-glucuronidase from human neutrophils in the presence of cartilage treated with various immunologic reactants.
Topics: Allopurinol; Arthritis, Rheumatoid; Aspirin; Cartilage; Chloroquine; Colchicine; Factor VIII; Glucuronidase; Hot Temperature; Humans; Immunoglobulin G; Indomethacin; Iodine Radioisotopes; L-Lactate Dehydrogenase; Methylprednisolone; Neutrophils; Peptide Hydrolases; Probenecid; Protein Denaturation; Sulfur Radioisotopes; Synovial Fluid; Triamcinolone Acetonide; Vinblastine | 1974 |
[Recent diagnostic and therapeutic acquisitions in malignant melanoma].
Topics: Antineoplastic Agents; Camptothecin; Chloroquine; Colchicine; Humans; Hydroxyurea; Imidazoles; Immunotherapy; Iodine Radioisotopes; Melanoma; Nitrosourea Compounds; Radionuclide Imaging; Triazenes | 1974 |
The effect of cytotoxic agents on autophagic vacuole formation in chloroquine-treated malaria parasites (Plasmodium berghei).
Topics: Animals; Antineoplastic Agents; Azaserine; Chloroquine; Colchicine; Cycloheximide; Cytoplasm; Dactinomycin; Malaria; Mercaptopurine; Mice; Mitomycins; Nucleic Acids; Pigments, Biological; Plasmodium; Protein Biosynthesis; Ribosomes; Uracil | 1971 |
Chemotherapy of experimental allergic encephalomyelitis (EAE).
Topics: Allopurinol; Aminocaproates; Analgesics; Animals; Antineoplastic Agents; Azathioprine; Body Weight; Chloroquine; Colchicine; Cortisone; Cyclophosphamide; Cyproheptadine; Diazoxide; Dimethyl Sulfoxide; Encephalomyelitis, Autoimmune, Experimental; Hydrocortisone; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Methyldopa; Nialamide; Oils; Organ Size; Rats; Strychnine; Talc; Thalidomide; Thioguanine; Thiomalates | 1969 |
Platelet reactions and immune processes. II. The inhibition of platelet aggregation by complement inhibitors.
Topics: Aldehydes; Blood Platelets; Catechols; Cell Membrane; Chloroquine; Colchicine; Collagen; Complement Fixation Tests; Complement Inactivator Proteins; Guaiacol; Humans; Latex Fixation Tests; Lupus Erythematosus, Systemic; ortho-Aminobenzoates; Phenylbutazone; Platelet Adhesiveness; Resorcinols; Salicylates; Silicones; Sodium; Sulfinpyrazone | 1969 |
Connective tissue cell mobilization and migration following wounding. I. Inhibition of mobilization by chloroquine and inhibition of migration by colchicine.
Topics: Animals; Cell Movement; Chloroquine; Colchicine; Coloring Agents; Connective Tissue; Connective Tissue Cells; Cornea; Corneal Injuries; Female; Fibroblasts; Freezing; Male; Organ Culture Techniques; Rabbits; Time Factors; Wound Healing | 1970 |
Diacytosis of 125I-asialoorosomucoid by rat hepatocytes. A non-lysosomal pathway insensitive to inhibition by inhibitors of ligand degradation.
Topics: Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Cells, Cultured; Chloroquine; Colchicine; Cold Temperature; Endocytosis; Endosomes; Exocytosis; Kinetics; Leupeptins; Liver; Lysosomes; Monensin; Rats; Receptors, Immunologic | 1984 |
The effects of ammonium ions and chloroquine on uptake and degradation of 125I-labeled asialo-fetuin in isolated rat hepatocytes.
Topics: alpha-Fetoproteins; Animals; Asialoglycoproteins; Biotransformation; Chloroquine; Colchicine; Digitonin; Fetuins; In Vitro Techniques; Liver; Male; Quaternary Ammonium Compounds; Rats; Subcellular Fractions | 1980 |
Uptake and degradation of desialylated luteinizing hormone by suspended hepatocytes.
Topics: alpha-Fetoproteins; Animals; Asialoglycoproteins; Biological Transport; Chloroquine; Colchicine; Cytochalasin B; Fetuins; Kinetics; Leupeptins; Liver; Luteinizing Hormone; Male; Rats | 1982 |
Effects of lysomotropic agents, and of microfilament- and microtubule-disrupting drugs on the activation of casein-gene expression by prolactin in the mammary gland.
Topics: Ammonium Chloride; Animals; Caseins; Chloroquine; Colchicine; Cytochalasin B; Cytoskeleton; Female; Lysosomes; Mammary Glands, Animal; Microtubules; Organ Culture Techniques; Prolactin; Rabbits; Receptors, Cell Surface; RNA, Messenger | 1980 |
Effects of lysosomotropic agents, cytochalasin B and colchicine on the "down-regulation" of prolactin receptors in mammary gland explants.
Topics: Animals; Binding, Competitive; Chloroquine; Colchicine; Cytochalasin B; Female; Insulin; Mammary Glands, Animal; Methylamines; Organ Culture Techniques; Prolactin; Rabbits; Receptors, Cell Surface | 1980 |
Epidermal growth factor stimulation of ornithine decarboxylase activity in a human hepatoma cell line.
Topics: Ammonium Chloride; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Enzyme Induction; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Liver Neoplasms; Ornithine Decarboxylase; Peptides; Receptors, Cell Surface | 1981 |
Low density lipoprotein receptor deficiency in cultured hepatocytes of the WHHL rabbit. Further evidence of two pathways for catabolism of exogenous proteins.
Topics: Animals; Cells, Cultured; Chloroquine; Colchicine; Female; Hydroxymethylglutaryl CoA Reductases; Hyperlipidemias; Kinetics; Lipoproteins, LDL; Liver; Rabbits; Receptors, Cell Surface; Receptors, LDL | 1981 |
Interaction of interferon with cellular receptors. Internalization and degradation of cell-bound interferon.
Topics: Biological Transport; Burkitt Lymphoma; Cell Line; Chloroquine; Colchicine; Cytochalasin D; Cytochalasins; Humans; Interferon Type I; Kinetics; Lysosomes; Methylamines; Receptors, Cell Surface; Receptors, Interferon; Temperature | 1982 |
Prolactin receptors in explant cultures of carcinogen-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chloroquine; Colchicine; Cycloheximide; Cytochalasin B; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Organoids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prolactin | 1983 |
Cytoskeletal disarrangement in rat intestinal epithelium after in vivo exposure to secretagogues.
Topics: Animals; Bacterial Toxins; Bucladesine; Chloroquine; Chlorpromazine; Cholera Toxin; Colchicine; Cytochalasin B; Cytoskeleton; Enterotoxins; Epithelium; Escherichia coli; Escherichia coli Proteins; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Rats; Rats, Inbred Strains | 1984 |
Catabolism of human low density lipoproteins by human hepatoma cell line HepG2.
Topics: Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Liver Neoplasms; Time Factors | 1984 |
Mechanism of autodegradation of cell-surface macromolecules shed by human melanoma cells.
Topics: Ammonium Chloride; Biological Transport; Cadaverine; Cell Line; Chloroquine; Coated Pits, Cell-Membrane; Colchicine; Cytochalasin B; Endocytosis; Humans; Leupeptins; Lysosomes; Melanoma; Membrane Proteins; Monensin; Neoplasm Proteins; Time Factors; Tunicamycin | 1984 |
The use of drugs in rheumatic diseases.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Aurothioglucose; Chloroquine; Colchicine; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Penicillamine; Prednisone; Rheumatic Diseases; Salicylates | 1984 |
Elastase activity in chick embryo fibroblasts, quantitative changes induced by agents which affect cell functions and variations during embryogenesis.
Topics: Animals; Cell Differentiation; Chick Embryo; Chloroquine; Colchicine; Cycloheximide; Fibroblasts; Pancreatic Elastase; Tunicamycin; Vinblastine | 1983 |
Binding and degradation of [125I]human growth hormone in rat adipocytes.
Topics: Adipose Tissue; Ammonium Chloride; Animals; Chloroquine; Colchicine; Growth Hormone; Humans; Iodine Radioisotopes; Leupeptins; Rats; Rats, Inbred Strains; Temperature; Time Factors | 1984 |
The internalisation of [125I] insulin by isolated rat hepatocytes.
Topics: Animals; Chloroquine; Colchicine; Diamide; Insulin; Liver; Male; Methylamines; Rats; Temperature; Time Factors | 1982 |
Release of fibrinolytic activators from the cornea and conjunctiva.
Topics: Animals; Chloroquine; Colchicine; Concanavalin A; Conjunctiva; Cornea; Female; Male; Plasminogen Activators; Prednisolone; Rabbits; Sodium Salicylate; Tears; Tetradecanoylphorbol Acetate; Thrombin | 1982 |
Phagocytosis of carbohydrate-modified phospholipid vesicles by macrophage.
Topics: Animals; Ascitic Fluid; Chloroquine; Cholesterol; Colchicine; Cytochalasin B; Glycolipids; Liposomes; Macrophages; Mice; Phagocytosis; Phospholipids | 1981 |
Cellular processing of insulin. Effects of lectin, lysosomotropic and other agents.
Topics: Animals; Cells, Cultured; Chloroquine; Colchicine; Concanavalin A; Insulin; Lectins; Liver; Rats; Vincristine | 1982 |
Transferrin uptake by cultured rat embryo fibroblasts. The influence of lysosomotropic agents, iron chelators and colchicine on the uptake of iron and transferrin.
Topics: Animals; Cells, Cultured; Chelating Agents; Chloroquine; Colchicine; Embryo, Mammalian; Endocytosis; Fibroblasts; Iron; Kinetics; Lysosomes; Methylamines; Rats; Subcellular Fractions; Transferrin | 1982 |
Inhibition of hepatocytic protein degradation by inducers of autophagosome accumulation.
Topics: Animals; Autophagy; Cadmium; Chloroquine; Colchicine; Liver; Male; Neutral Red; Octoxynol; Phagocytosis; Polyethylene Glycols; Proteins; Puromycin; Rats; Rats, Inbred Strains; Sucrose; Vinblastine | 1982 |
Rat eosinophil-mediated antibody-dependent cellular cytotoxicity: investigations of the mechanisms of target cell lysis and inhibition by glucocorticoids.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Chloroquine; Colchicine; Cycloheximide; Cytochalasin B; Eosinophils; Female; Methylprednisolone; Rats; Rats, Inbred Strains; Receptors, Fc | 1982 |
Endocytosis of heat-denatured albumin by cultured rat Kupffer cells.
Topics: Animals; Antimycin A; Cattle; Cells, Cultured; Chloroquine; Colchicine; Colloids; Endocytosis; Female; Fluorides; Glycolysis; Hot Temperature; Iodine Radioisotopes; Kinetics; Kupffer Cells; Mitochondria, Liver; Rats; Rats, Inbred BN; Serum Albumin, Bovine; Time Factors | 1982 |
The effect of ammonia, chloroquine, leupeptin, colchicine and cytochalasin B on degradation of high density lipoproteins in isolated rat hepatocytes.
Topics: Ammonia; Animals; Cells, Cultured; Chloroquine; Colchicine; Cytochalasin B; Cytoskeleton; Depression, Chemical; Drug Interactions; Endocytosis; Leupeptins; Lipoproteins, HDL; Liver; Lysosomes; Male; Microtubules; Oligopeptides; Rats | 1980 |
Factors that influence the uptake of beta-hexosaminidase A by rat peritoneal macrophages.
Topics: Acetylglucosaminidase; Ammonium Chloride; Animals; Biological Transport; Chloroquine; Colchicine; Cytochalasin B; Female; Glycoproteins; Hexosaminidases; Humans; Kinetics; Macrophages; Methylamines; Phagocytosis; Placenta; Pregnancy; Quinacrine; Rats | 1980 |
Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Base Sequence; Biological Transport; Cell Survival; Chloroquine; CHO Cells; Colchicine; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Protozoan; Doxorubicin; Drug Resistance; Female; Gene Expression; Genes, Protozoan; Membrane Proteins; Oligonucleotides, Antisense; Oocytes; Plasmodium falciparum; Primaquine; Protozoan Proteins; Quinine; Restriction Mapping; Verapamil; Vinblastine; Xenopus laevis | 1994 |
Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells.
Topics: Amino Acid Sequence; Ammonium Chloride; Animals; Arsenicals; Cell Line, Transformed; Chloroquine; Colchicine; Endocytosis; Epithelium; Hypertonic Solutions; Immune Sera; Immunohistochemistry; Kinetics; Leupeptins; Microscopy, Fluorescence; Molecular Sequence Data; Monensin; Peptides; Rats; Receptors, Neurokinin-1; Recombinant Proteins; Substance P; Time Factors; Transfection | 1994 |
Role of cytoskeleton and acidification of endocytic compartment in asialoglycoprotein metabolism in isolated rat hepatocyte couplets.
Topics: Acids; alpha-Fetoproteins; Animals; Asialoglycoproteins; Cell Separation; Chloroquine; Colchicine; Cytochalasin B; Cytoskeleton; Endocytosis; Fetuins; Gold; Horseradish Peroxidase; Liver; Male; Microscopy, Electron; Rats; Rats, Wistar | 1995 |
Liposome-encapsulated DNA-mediated gene transfer and synthesis of human factor IX in mice.
Topics: Animals; Chloroquine; Colchicine; DNA; Factor IX; Gene Transfer Techniques; Genetic Therapy; Hemophilia B; Humans; Injections, Intravenous; Liposomes; Liver; Mice; Mice, Inbred BALB C; Mice, Transgenic; Plasmids; Spleen; Tissue Distribution | 1995 |
A P-glycoprotein protects Caenorhabditis elegans against natural toxins.
Topics: Animals; Animals, Genetically Modified; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chloroquine; Colchicine; DNA, Helminth; Drug Resistance; Genes, Helminth; Helminth Proteins; Microscopy, Electron; Molecular Sequence Data; Mutation; Tissue Distribution; Toxins, Biological | 1995 |
Angiotensin II (AII)-binding sites in nuclei from rat liver: partial characterization of the mechanism of AII accumulation in nuclei.
Topics: Angiotensin II; Animals; Cell Fractionation; Cell Membrane; Cell Nucleus; Chloroquine; Colchicine; Isoelectric Focusing; Liver; Male; Rats; Rats, Wistar; Receptors, Angiotensin | 1994 |
Characteristics of invasion of HEp-2 cells by Providencia alcalifaciens.
Topics: Adolescent; Adult; Ammonium Chloride; Cadaverine; Cell Line; Child; Child, Preschool; Chloroquine; Colchicine; Cytochalasin D; Diarrhea; Diarrhea, Infantile; Enterobacteriaceae Infections; Female; Humans; Immunosuppressive Agents; Infant; Male; Middle Aged; Providencia; Temperature; Time Factors | 1995 |
Hepatectomy impairs hepatic processing of somatostatin-14.
Topics: Animals; Biological Transport; Chloroquine; Colchicine; Hepatectomy; Iodine Radioisotopes; Leupeptins; Liver; Liver Regeneration; Male; Rats; Rats, Sprague-Dawley; Somatostatin; Vinblastine | 1993 |
Inhibitors of endocytosis, endosome fusion, and lysosomal processing inhibit the intracellular proteolysis of the amyloid precursor protein.
Topics: Adenine; Amyloid beta-Protein Precursor; Animals; Chloroquine; Colchicine; Cytochalasin B; Endocytosis; Lysosomes; Monensin; Organelles; PC12 Cells; Rats | 1993 |
Albumin-binding proteins function in the receptor-mediated binding and transcytosis of albumin across cultured endothelial cells.
Topics: Animals; Antibodies, Anti-Idiotypic; Arachidonic Acid; Binding, Competitive; Biological Transport; Cattle; Cells, Cultured; Chloroquine; Colchicine; Endothelium, Vascular; Oleic Acid; Oleic Acids; Receptors, Albumin; Serum Albumin | 1993 |
Differential host susceptibility to intracerebral infections with Candida albicans and Cryptococcus neoformans.
Topics: Animals; Brain Diseases; Candidiasis; Chloroquine; Colchicine; Cryptococcosis; Disease Susceptibility; Female; Macrophages; Mice; Picolinic Acids | 1993 |
Brefeldin A blocks the cytotoxicity of T cell receptor alpha/beta and gamma/delta cytotoxic T lymphocyte clones reacting against human autologous cancer cells.
Topics: Brefeldin A; Chloroquine; Colchicine; Cycloheximide; Cyclopentanes; Cytotoxicity Tests, Immunologic; Humans; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1993 |
Degradation of radioiodinated B cell monoclonal antibodies: inhibition via a FCgamma-receptor-II-mediated mechanism and by drugs.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; B-Lymphocytes; Biological Transport; Burkitt Lymphoma; Calcium Channel Blockers; Cell Adhesion Molecules; Chloroquine; Colchicine; Etoposide; Humans; Immunoglobulin Isotypes; Immunotoxins; Iodine Radioisotopes; Lectins; Leukemia, B-Cell; Mice; Monensin; Paclitaxel; Radioimmunotherapy; Receptors, IgG; Sialic Acid Binding Ig-like Lectin 2; Verapamil; Vinblastine; Vincristine | 1996 |
Dexamethasone and colchicine reduce inflammation and delayed oedema following experimental brain contusion.
Topics: Animals; Anti-Inflammatory Agents; Brain; Brain Concussion; Brain Damage, Chronic; Brain Edema; Chloroquine; Colchicine; Dexamethasone; Encephalitis; Female; Gout Suppressants; Immunoenzyme Techniques; Nerve Degeneration; Rats; Rats, Sprague-Dawley | 1996 |
Potentiation of angiotensin II action by corticosteroids in vascular tissue.
Topics: Adrenal Cortex Hormones; Angiotensin II; Animals; Chloroquine; Colchicine; Immunoblotting; In Vitro Techniques; Methionine; Muscle, Smooth, Vascular; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Up-Regulation; Vasoconstriction | 1996 |
Gap junction endocytosis and lysosomal degradation of connexin43-P2 in WB-F344 rat liver epithelial cells treated with DDT and lindane.
Topics: Animals; Blotting, Western; Cells, Cultured; Chloroquine; Colchicine; Connexin 43; DDT; Endocytosis; Epithelium; Gap Junctions; Hexachlorocyclohexane; Kinetics; Liver; Lysosomes; Phosphorylation; Rats; Rats, Inbred F344 | 1996 |
Tumor necrosis factor soluble receptor 75: the principal receptor form released by human alveolar macrophages and monocytes in the presence of interferon gamma.
Topics: Animals; Antigens, CD; Cells, Cultured; Chloroquine; Colchicine; Culture Media; Growth Substances; Humans; Interferon-gamma; L Cells; Lipopolysaccharides; Macrophage Activation; Macrophages, Alveolar; Mice; Microtubules; Monensin; Monocytes; Protein Synthesis Inhibitors; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Endothelin converting enzyme is located on alpha-actin filaments in smooth muscle cells.
Topics: Actins; Animals; Aspartic Acid Endopeptidases; Biotinylation; Cell Line; Cell Membrane; Cells, Cultured; Chloroquine; Chromatography, High Pressure Liquid; Colchicine; Cytochalasin D; Endothelin-Converting Enzymes; Fluorescent Antibody Technique; Glycopeptides; Humans; Metalloendopeptidases; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Protease Inhibitors; Rats; Umbilical Arteries | 1999 |
[Neuromuscular complications of long-term treatment of inflammatory diseases. 3 cases].
Topics: Adult; Behcet Syndrome; Chloroquine; Colchicine; Familial Mediterranean Fever; Female; Follow-Up Studies; Humans; Iatrogenic Disease; Lupus Erythematosus, Systemic; Male; Middle Aged; Neuromuscular Diseases; Time Factors | 1999 |
Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MHC antigens.
Topics: Ammonium Chloride; Animals; Antibody Specificity; Antigen Presentation; Antigen-Presenting Cells; Blood Donors; Blood Platelets; Brefeldin A; Chloroquine; Colchicine; Cytosol; Endocytosis; Endosomes; Enzyme Activation; Female; H-2 Antigens; Immunoglobulin G; Interleukin-4; Isoantibodies; Leupeptins; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microtubules; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Transfusion; T-Lymphocytes, Helper-Inducer; Tubulin | 2000 |
Temporal profile of release of interleukin-1beta in neurotrauma.
Topics: Animals; Brain; Brain Injuries; Chloroquine; Colchicine; Immunohistochemistry; Inflammation; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Male; Microdialysis; Microglia; Rats; Rats, Wistar; RNA, Messenger; Serpins; Time Factors; Viral Proteins | 2000 |
Fibroblast growth factors are translocated to the nucleus of human endothelial cells in a microtubule- and lysosome-independent pathway.
Topics: Biological Transport, Active; Cell Nucleus; Cells, Cultured; Chloroquine; Colchicine; Cytosol; Endothelium, Vascular; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Fibroblast Growth Factors; Humans; Kinetics; Leupeptins; Lysosomes; Microtubules; Subcellular Fractions | 2000 |
Transcytosis and coenzymatic conversion of [(57)Co]cobalamin bound to either endogenous transcobalamin II or exogenous intrinsic factor in caco-2 cells.
Topics: Biological Transport; Caco-2 Cells; Cell Polarity; Chloroquine; Cobalt Radioisotopes; Colchicine; Edetic Acid; Humans; Intrinsic Factor; Transcobalamins; Vitamin B 12 | 2000 |
Monocyte inhibitors as a potent immunosuppressant in rodent heart transplantation.
Topics: Animals; Chloroquine; Colchicine; Cytokines; Graft Survival; Heart Transplantation; Interferon-gamma; Interleukins; Lymphotoxin-alpha; Monocytes; Rats; Rats, Inbred Lew; Rats, Wistar; Time Factors; Transplantation, Homologous; Tumor Necrosis Factor-alpha | 2000 |
A C. elegans orphan nuclear receptor contributes to xenobiotic resistance.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Biodegradation, Environmental; Biological Transport; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chloroquine; Colchicine; Digestive System; Drug Resistance; Gene Expression Regulation; Genes, Helminth; Helminth Proteins; Receptors, Cytoplasmic and Nuclear; Xenobiotics | 2001 |
HAEMATOLOGICAL SIDE-EFFECTS OF SOME ANTI-RHEUMATIC DRUGS.
Topics: Aminopyrine; Antirheumatic Agents; Aspirin; Blood Platelets; Chloroquine; Colchicine; Complement Fixation Tests; Drug Hypersensitivity; Gold; Humans; Hydroxychloroquine; Meprobamate; Phenacetin; Phenylbutazone; Probenecid; Purpura; Purpura, Thrombocytopenic; Quinacrine; Rheumatic Diseases; Splenectomy; Toxicology | 1963 |
EXPERIMENTAL ANALYSIS OF ISOMORPHIC (KOEBNER) RESPONSE IN PSORIASIS.
Topics: Chloroquine; Colchicine; Cold Temperature; Dermabrasion; Histology; Humans; Idoxuridine; Iontophoresis; Lidocaine; Psoriasis; Vasodilator Agents; Wounds and Injuries | 1964 |
SOME CHEMICAL INFLUENCES ON HAIR GROWTH AND PIGMENTATION.
Topics: Alopecia; Aminopterin; Anticoagulants; Child; Chloroquine; Colchicine; Cyclophosphamide; Geriatrics; Hair; Humans; Mephenesin; Neoplasms; Pigmentation; Plant Poisoning; Poisoning; Thallium; Toxicology; Triparanol; Tyrosine Decarboxylase; Vitamin A | 1965 |
A novel type of PTD, common helix-loop-helix motif, could efficiently mediate protein transduction into mammalian cells.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Chloroquine; Colchicine; Endocytosis; Helix-Loop-Helix Motifs; Heparin; Humans; Male; Membrane Microdomains; Microphthalmia-Associated Transcription Factor; Nerve Tissue Proteins; Pinocytosis; Protein Structure, Tertiary; Protein Transport; Rats; Sodium Azide; Transcriptional Activation | 2006 |
Familial linear scleroderma (en coup de sabre) responsive to antimalarials and narrowband ultraviolet B therapy.
Topics: Adult; Antimalarials; Chloroquine; Colchicine; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; Forehead; Genetic Predisposition to Disease; Gout Suppressants; Humans; Scleroderma, Localized; Ultraviolet Therapy | 2007 |
Enhancement of gene expression efficiency using cationic liposomes on ovarian cancer cells.
Topics: Ammonium Chloride; Cations; Cell Line, Tumor; Chloroquine; Colchicine; Female; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Humans; Liposomes; Microscopy, Confocal; Ovarian Neoplasms; Transfection | 2008 |
Quantitation of "autophagic flux" in mature skeletal muscle.
Topics: Animals; Antirheumatic Agents; Autophagy; Cell Line; Chloroquine; Colchicine; Humans; Male; Mice; Microtubule-Associated Proteins; Muscle Denervation; Muscle, Skeletal; Protein Isoforms; Tubulin Modulators; Vinblastine | 2010 |