Compounds > chloroquine

chloroquine and clofazimine

chloroquine has been researched along with clofazimine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Barteselli, A; Basilico, N; Boido, V; Casagrande, M; Parapini, S; Rusconi, CM; Sparatore, A; Sparatore, F; Taramelli, D; Tonelli, M1
Trautman, JR1
Kashyap, A; Saha, K; Sehgal, VN1
Pfaltzgraff, RE1
Sehgal, VN; Sharma, V; Sharma, VK1
Razack, EM; Zahra, A1
Bhattacharya, SN; Chattopadhaya, D; Saha, K1
Bezerra, EL; da Trindade Neto, PB; Sato, EI; Vilar, MJ1

Trials

1 trial(s) available for chloroquine and clofazimine

ArticleYear
Double-blind, randomized, controlled clinical trial of clofazimine compared with chloroquine in patients with systemic lupus erythematosus.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Chloroquine; Clofazimine; Double-Blind Method; Female; Humans; Lupus Erythematosus, Systemic; Male; Remission Induction; Skin Diseases; Treatment Outcome

2005

Other Studies

11 other study(ies) available for chloroquine and clofazimine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Clofazimine analogs with antileishmanial and antiplasmodial activity.
    Bioorganic & medicinal chemistry, 2015, Jan-01, Volume: 23, Issue:1

    Topics: Anti-Inflammatory Agents; Antimalarials; Antiprotozoal Agents; Cell Line; Clofazimine; Endothelial Cells; Humans; Leishmania; Plasmodium falciparum

2015
Treatment of Hansen's disease.
    Cutis, 1976, Volume: 18, Issue:1

    Topics: Chloroquine; Clofazimine; Dapsone; Drug Resistance, Microbial; Erythema Nodosum; Humans; Leprosy; Prednisone; Rifampin; Thalidomide

1976
Reconstruction of anti-leprosy drug depleted complement haemolytic activity by addition of zymosan-treated sera (a source of C142) and CratEDTA (a source of C3-C9).
    International journal of immunopharmacology, 1992, Volume: 14, Issue:8

    Topics: Animals; Chloroquine; Clofazimine; Complement Activation; Complement System Proteins; Dapsone; Edetic Acid; Guinea Pigs; Hemolysis; Humans; Rats; Zymosan

1992
The management of reaction in leprosy.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1989, Volume: 57, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Benzenesulfonates; Chloroquine; Clofazimine; Cytotoxicity, Immunologic; Humans; Immunity, Cellular; Inflammation; Leprosy; Splints; Surgical Procedures, Operative; Thalidomide

1989
The effect of anti-reactional drugs on complement components in the type II, erythema nodosum leprosum, reaction.
    The British journal of dermatology, 1988, Volume: 119, Issue:2

    Topics: Chloroquine; Clofazimine; Complement C3; Complement Factor B; Complement System Proteins; Erythema Nodosum; Humans; Leprosy; Prednisolone

1988
Multi-drug treatment for reactions in leprosy.
    Leprosy in India, 1981, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Child; Chloroquine; Clofazimine; Diethylcarbamazine; Drug Therapy, Combination; Female; Humans; Leprosy; Male; Metronidazole; Middle Aged; Prednisolone

1981
Tumor necrosis factor: status in reactions in leprosy before and after treatment.
    International journal of dermatology, 1993, Volume: 32, Issue:6

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Clofazimine; Erythema Nodosum; Female; Humans; Hypersensitivity, Delayed; Leprostatic Agents; Leprosy, Borderline; Leprosy, Lepromatous; Leprosy, Tuberculoid; Male; Prednisolone; Tablets; Tumor Necrosis Factor-alpha

1993