chloroquine and clindamycin

chloroquine has been researched along with clindamycin in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19909 (31.03)18.7374
1990's4 (13.79)18.2507
2000's8 (27.59)29.6817
2010's8 (27.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karmodiya, K; Mishra, S; Ramya, TN; Surolia, A; Surolia, N1
Dahl, EL; Rosenthal, PJ1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aikawa, M; Nugent, KM; Powers, KG1
Doberstyn, EB; Hall, AP; Nanokorn, A; Sonkom, P1
el-Fakahany, AF; el-Ridi, AM; Hamadto, HH; Marii, NE; Rashed, SM; Sobhy, MM1
Klempner, MS; Styrt, B1
Schmidt, LH1
Jackson, EA; McLeod, DC1
Divo, AA; Geary, TG; Jensen, JB1
Brodasky, TF; Gluzman, IY; Krogstad, DJ; Parquette, AR; Phillips, GW; Seaberg, LS1
Pazzaglia, G; Woodward, WE1
Bienzle, U; Graninger, W; Jenne, L; Kremsner, PG; Wildling, E1
Bienzle, U; Brandts, C; Graninger, W; Kremsner, PG; Neifer, S; Winkler, S1
Bienzle, U; Brandts, C; Graninger, W; Kremsner, PG; Winkler, S1
Bienzle, U; Graninger, W; Kremsner, PG; Metzger, W; Mordmüller, B1
Kremsner, PG; Lell, B1
Chandramohan, D; Chico, RM1
Fuehrer, HP; Ganesh, D; Graninger, W; Haque, R; Khan, WA; Noedl, H; Starzengruber, P; Swoboda, P1
Andrews, KT; Arnold, MS; Chua, MJ; Engel, JA; Fisher, GM; Skinner-Adams, TS1
Chen, H; Huang, S; Jin, L; Li, J; Ni, Q; Pan, C; Yao, L; Zhang, L1

Reviews

2 review(s) available for chloroquine and clindamycin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clindamycin as an antimalarial drug: review of clinical trials.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Antimalarials; Chloroquine; Clindamycin; Drug Combinations; Female; Humans; Malaria; Plasmodium vivax; Pregnancy; Quinine

2002

Trials

4 trial(s) available for chloroquine and clindamycin

ArticleYear
Comparison of micronized halofantrine with chloroquine-antibiotic combinations for treating Plasmodium falciparum malaria in adults from Gabon.
    The American journal of tropical medicine and hygiene, 1994, Volume: 50, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antimalarials; Chloroquine; Clindamycin; Doxycycline; Drug Therapy, Combination; Female; Follow-Up Studies; Gabon; Humans; Malaria, Falciparum; Male; Middle Aged; Phenanthrenes

1994
Clindamycin in combination with chloroquine or quinine is an effective therapy for uncomplicated Plasmodium falciparum malaria in children from Gabon.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Chloroquine; Clindamycin; Drug Therapy, Combination; Female; Gabon; Humans; Malaria, Falciparum; Male; Quinine

1994
Curing of chloroquine-resistant malaria with clindamycin.
    The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:5

    Topics: Adolescent; Adult; Aged; Animals; Chloroquine; Clindamycin; Drug Resistance; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Recurrence

1993
Sulfadoxine/pyrimethamine or chloroquine/clindamycin treatment of Gabonese school children infected with chloroquine resistant malaria.
    The Journal of antimicrobial chemotherapy, 1995, Volume: 36, Issue:4

    Topics: Adolescent; Animals; Anti-Bacterial Agents; Antimalarials; Child; Child, Preschool; Chloroquine; Clindamycin; Drug Combinations; Drug Resistance; Female; Gabon; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine

1995

Other Studies

23 other study(ies) available for chloroquine and clindamycin

ArticleYear
Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Acetone; Animals; Antimalarials; Azithromycin; Cerulenin; Chloramphenicol; Clindamycin; Erythrocytes; Fatty Acids; Gene Dosage; Humans; Organelles; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Tetracycline; Thioctic Acid; Triclosan

2007
Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Antimalarials; Drug Resistance; Flow Cytometry; Green Fluorescent Proteins; Plasmodium falciparum; Protein Synthesis Inhibitors; Topoisomerase II Inhibitors

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Plasmodium knowlesi: morphology and course of infection in rhesus monkeys treated with clindamycin and its N-demethyl-4'-pentyl analog.
    Experimental parasitology, 1976, Volume: 40, Issue:1

    Topics: Animals; Blood; Chloroquine; Clindamycin; Endoplasmic Reticulum; Erythrocytes; Haplorhini; Macaca mulatta; Malaria; Mitochondrial Swelling; Plasmodium; Ribosomes

1976
Falciparum malaria semi-resistant to clindamycin.
    British medical journal, 1975, Apr-05, Volume: 2, Issue:5961

    Topics: Blood; Child; Chloroquine; Clindamycin; Colitis; Digestive System; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male; Plasmodium falciparum; Quinine; Tetracycline

1975
The effect of some drugs on acute toxoplasmosis in mice.
    Journal of the Egyptian Society of Parasitology, 1989, Volume: 19, Issue:2

    Topics: Animals; Chloroquine; Clindamycin; Drug Combinations; Levamisole; Mice; Praziquantel; Sulfamethoxazole; Toxoplasmosis, Animal; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1989
Inhibition of neutrophil oxidative metabolism by lysosomotropic weak bases.
    Blood, 1986, Volume: 67, Issue:2

    Topics: Ammonium Chloride; Chloroquine; Clindamycin; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lysosomes; Methylamines; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate

1986
Enhancement of the curative activity of primaquine by concomitant administration of mirincamycin.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:2

    Topics: Animals; Antimalarials; Chloroquine; Clindamycin; Drug Therapy, Combination; Female; Macaca mulatta; Malaria; Male; Plasmodium vivax; Primaquine

1985
Pharmacokinetics and dosing of antimicrobial agents in renal impairment, Part II.
    American journal of hospital pharmacy, 1974, Volume: 31, Issue:2

    Topics: Anti-Infective Agents; Bacitracin; Chloramphenicol; Chloroquine; Clindamycin; Dapsone; Ethambutol; Humans; Isoniazid; Kidney Diseases; Methenamine; Nalidixic Acid; Neomycin; Nitrofurantoin; Sulfadimethoxine; Sulfamethizole; Sulfamethoxazole; Sulfamethoxypyridazine; Sulfisomidine; Sulfisoxazole; Vancomycin

1974
An in vitro assay system for the identification of potential antimalarial drugs.
    The Journal of parasitology, 1983, Volume: 69, Issue:3

    Topics: Animals; Antimalarials; Cattle; Chloramphenicol; Chloroquine; Clindamycin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Piperidines; Plasmodium falciparum; Quinazolines; Quinazolinones; Rabbits

1983
Clindamycin activity against chloroquine-resistant Plasmodium falciparum.
    The Journal of infectious diseases, 1984, Volume: 150, Issue:6

    Topics: Chloroquine; Clindamycin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Synergism; Hypoxanthine; Hypoxanthines; Plasmodium falciparum

1984
An analysis of the relationship of host factors to clinical falciparum malaria by multiple regression techniques.
    The American journal of tropical medicine and hygiene, 1982, Volume: 31, Issue:2

    Topics: Adult; Age Factors; Black People; Body Weight; Chloroquine; Clindamycin; Fever; Humans; Malaria; Male; Plasmodium falciparum; Quinine; Recurrence; Regression Analysis; White People

1982
Quinine for the treatment of malaria in pregnancy.
    The Lancet. Infectious diseases, 2010, Volume: 10, Issue:3

    Topics: Animals; Antimalarials; Azithromycin; Chloroquine; Clindamycin; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Quinine

2010
Mirincamycin, an old candidate for malaria combination treatment and prophylaxis in the 21st century: in vitro interaction profiles with potential partner drugs in continuous culture and field isolates.
    Malaria journal, 2014, Jun-10, Volume: 13

    Topics: Adolescent; Adult; Aged; Aminoquinolines; Antimalarials; Artemisinins; Child; Chloroquine; Clindamycin; Drug Interactions; Female; Humans; Male; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Young Adult

2014
Adaptation of the [3H]Hypoxanthine Uptake Assay for In Vitro-Cultured Plasmodium knowlesi Malaria Parasites.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7

    Topics: Animals; Antimalarials; Chloroquine; Clindamycin; Hypoxanthine; Inhibitory Concentration 50; Malaria; Plasmodium falciparum; Plasmodium knowlesi; Proguanil; Triazines

2016
Human babesiosis in Southeast China: A case report.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2018, Volume: 68

    Topics: Administration, Intravenous; Anemia, Hemolytic; Anti-Bacterial Agents; Azithromycin; Babesiosis; C-Reactive Protein; China; Chloroquine; Clindamycin; Female; Fever; Humans; Middle Aged; Neutropenia; Thrombocytopenia

2018