chloroquine has been researched along with chlorpheniramine in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (15.38) | 18.7374 |
| 1990's | 7 (17.95) | 18.2507 |
| 2000's | 18 (46.15) | 29.6817 |
| 2010's | 8 (20.51) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Cooper, RA; Dodean, RA; Hinrichs, DJ; Janowsky, A; Johnson, RA; Kelly, JX; Lane, KD; Riscoe, M; Smilkstein, MJ; Winter, R | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Sen, S; Sinha, N | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Okor, RS | 1 |
| Mnyika, KS | 1 |
| Onaya, T | 1 |
| Hochschild, R | 1 |
| Picchioni, AL | 1 |
| Chin, L; Duplisse, BR; Picchioni, AL | 1 |
| Chin, L; Gillespie, T; Picchioni, AL | 2 |
| Osifo, NG | 1 |
| Basco, LK; Le Bras, J | 1 |
| Bagla, P | 1 |
| Jin, LJ; Li, SF | 1 |
| Andrisano, V; Cavrini, V; Gotti, R; Mascellani, G | 1 |
| Adedeji, AA; Akinyinka, OO; Falade, AG; Falade, CO; Fehintola, FA; Oduola, AM; Sowunmi, A | 1 |
| Adedeji, AA; Ayede, AI; Falade, AG; Falade, CO; Happi, TC; Ndikum, VN; Oduola, AM; Sowunmi, A; Sowunmi, CO | 1 |
| Adedeji, AA; Sowunmi, A | 1 |
| Adedeji, AA; Fateye, BA; Fehintola, FA; Happi, TC; Sowunmi, A | 1 |
| Adedeji, AA; Fateye, BA; Fehintola, FA; Gbotosho, GO; Happi, TC; Oduola, AM; Sowunmi, A | 1 |
| Gbotosho, GO; Gerena, L; Happi, CT; Kyle, DE; Milhous, WK; Oduola, AM; Ogundahunsi, OA; Salako, LA; Sowunmi, A | 1 |
| Adedeji, AA; Fateye, BA; Gbotosho, GO; Happi, TC; Sowunmi, A | 1 |
| Adedeji, AA; Bolaji, OM; Fateye, BA; Fehintola, FA; Gbotosho, GO; Happi, CT; Oduola, AM; Sowunmi, A | 1 |
| Gbotosho, GO; Happi, CT; Oduola, AM; Ogundahunsi, OA; Sijuade, A; Sowunmi, A | 1 |
| Kolawole, SO; Ogungbamigbe, TO; Ogunro, PS; Ojurongbe, O; Okanlawon, BM | 1 |
| Adedapo, AD; Adedapo, KS; Ademowo, OG; Demissie, K; Osinubi, OY | 1 |
| Alcantara, LM; Ayong, LS; Franco, CH; Franzoi, KD; Freitas-Junior, LH; Kim, J; Lee, S; Moraes, CB | 1 |
3 review(s) available for chloroquine and chlorpheniramine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Thyroid stimulating hormone (TSH)].
Topics: Adenylyl Cyclases; Animals; Chloroquine; Chlorpheniramine; Cyclic AMP; Dactinomycin; Iodine; Lysosomes; Phlorhizin; Phospholipids; Prostaglandins; Protein Biosynthesis; Rats; Thioridazine; Thyroid Gland; Thyrotropin; Trifluoperazine | 1971 |
Activated charcoal. A neglected antidote.
Topics: Antidotes; Aspirin; Barbiturates; Charcoal; Child; Chloroquine; Chlorpheniramine; Humans; Intestinal Absorption; Poisoning; Time Factors | 1970 |
9 trial(s) available for chloroquine and chlorpheniramine
| Article | Year |
|---|---|
The efficacy of piriton on chloroquine-induced pruritus in patients with malaria.
Topics: Chloroquine; Chlorpheniramine; Female; Humans; Malaria; Male; Pruritus | 1991 |
The antipruritic effects of chlorpheniramine, cyproheptadine and sulphapyridine monitored with limb activity meters on chloroquine induced pruritus among patients with malaria.
Topics: Adolescent; Adult; Antimalarials; Antipruritics; Chloroquine; Chlorpheniramine; Cyproheptadine; Dermatologic Agents; Drug Monitoring; Extremities; Humans; Malaria; Male; Movement; Pruritus; Sulfapyridine | 1995 |
Comparative efficacy of chloroquine plus chlorpheniramine alone and in a sequential combination with sulfadoxine-pyrimethamine, for the treatment of acute, uncomplicated, falciparum malaria in children.
Topics: Animals; Antimalarials; Antipruritics; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Administration Schedule; Drug Therapy, Combination; Fever; Germ Cells; Humans; Infant; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2000 |
Randomized comparison of chloroquine and amodiaquine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Age Factors; Amodiaquine; Analysis of Variance; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Normal Distribution; Parasitemia; Statistics, Nonparametric; Time Factors; Treatment Outcome | 2001 |
The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Acute Disease; Adolescent; Amodiaquine; Antimalarials; Area Under Curve; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Therapy, Combination; Hepatomegaly; Humans; Infant; Malaria, Falciparum; Prospective Studies; Treatment Outcome | 2002 |
Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children.
Topics: Amodiaquine; Animals; Antimalarials; Carrier State; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Nigeria; Parasitemia; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Regression Analysis; Risk Factors; Sulfadoxine | 2004 |
Predictors of the failure of treatment with chloroquine plus chlorpheniramine, in children with acute, uncomplicated, Plasmodium falciparum malaria.
Topics: Acute Disease; Age Factors; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Prospective Studies; Risk Factors; Statistics as Topic; Treatment Failure; Treatment Outcome | 2005 |
Comparative study of interactions between chloroquine and chlorpheniramine or promethazine in healthy volunteers: a potential combination-therapy phenomenon for resuscitating chloroquine for malaria treatment in Africa.
Topics: Adult; Animals; Antimalarials; Area Under Curve; Chloroquine; Chlorpheniramine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Promethazine | 2008 |
Potential toxicity of chlorpheniramine plus chloroquine for the treatment of childhood malaria.
Topics: Adolescent; Antimalarials; Antipruritics; Chi-Square Distribution; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Statistics, Nonparametric; Treatment Outcome | 2009 |
27 other study(ies) available for chloroquine and chlorpheniramine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum.
Topics: Acridones; Animals; Antimalarials; Cell Survival; Cells, Cultured; Drug Design; Drug Interactions; Drug Resistance, Multiple; Lymphocytes; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Molecular Structure; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Onset of pruritogenicity of chloroquine and the implication for the timing of suppressive therapy.
Topics: Adult; Chloroquine; Chlorpheniramine; Humans; Pruritus | 1991 |
Effects of various drugs on longevity in female C57BL-6J mice.
Topics: Acetaminophen; Age Factors; Analgesics; Animals; Aspirin; Body Weight; Buffers; Cell Membrane; Chemical Phenomena; Chemistry; Chloroquine; Chlorpheniramine; Chlorpromazine; Female; Glycolates; Longevity; Mice; Mice, Inbred C57BL | 1973 |
The action of activated charcoal on poisons in the digestive tract.
Topics: Animals; Aspirin; Barbiturates; Charcoal; Chloroquine; Chlorpheniramine; Chlorpromazine; Digestive System; Dogs; Glutethimide; Intestinal Absorption; Liver; Male; Pentobarbital; Poisoning; Rats; Time Factors | 1970 |
Evaluation of activated charcoal-sorbitol suspension as an antidote.
Topics: Animals; Antidotes; Aspirin; Charcoal; Chloroquine; Chlorpheniramine; Drug Combinations; Drug Evaluation, Preclinical; Liver; Male; Pentobarbital; Rats; Rats, Inbred Strains; Sorbitol | 1982 |
Saline cathartics and saline cathartics plus activated charcoal as antidotal treatments.
Topics: Animals; Antidotes; Aspirin; Cathartics; Charcoal; Chloroquine; Chlorpheniramine; Female; Pentobarbital; Rats; Sodium; Sulfates | 1981 |
In vitro reversal of chloroquine resistance with chlorpheniramine against African isolates of Plasmodium falciparum.
Topics: Africa; Animals; Chloroquine; Chlorpheniramine; Drug Resistance; Humans; Plasmodium falciparum | 1994 |
Malaria fighters gather at site of early victory.
Topics: Acquired Immunodeficiency Syndrome; Africa; Animals; Animals, Genetically Modified; Anopheles; Antimalarials; Chloroquine; Chlorpheniramine; Drug Resistance; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; India; Insect Vectors; Malaria; Plasmodium | 1997 |
Comparison of chiral recognition capabilities of cyclodextrins for the separation of basic drugs in capillary zone electrophoresis.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Antimalarials; beta-Cyclodextrins; Chloroquine; Chlorpheniramine; Cyclodextrins; Electrophoresis, Capillary; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Molecular Conformation; Sulfates | 1998 |
Semisynthetic chondroitins as chiral buffer additives in capillary electrophoresis.
Topics: Anions; Buffers; Chloroquine; Chlorpheniramine; Chondroitin Sulfates; Dermatan Sulfate; Dimethindene; Electrophoresis, Capillary; Heparin; Humans; Hydrogen-Ion Concentration; Stereoisomerism | 1999 |
The effects of alpha1-acid glycoprotein on the reversal of chloroquine resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Calcium Channel Blockers; Chloroquine; Chlorpheniramine; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Enzyme Inhibitors; Histamine H1 Antagonists; Orosomucoid; Plasmodium falciparum; Promethazine; Verapamil | 2006 |
Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Combinations; Drug Therapy, Combination; Gametogenesis; Histamine H1 Antagonists; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Time Factors; Treatment Outcome | 2006 |
Enhancement of the antimalarial efficacy of amodiaquine by chlorpheniramine in vivo.
Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Synergism; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Infant; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins | 2007 |
Chloroquine resistant Plasmodium falciparum malaria in Osogbo Nigeria: efficacy of amodiaquine + sulfadoxine-pyrimethamine and chloroquine + chlorpheniramine for treatment.
Topics: Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Clinical Protocols; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2008 |
Chemosensitization potential of P-glycoprotein inhibitors in malaria parasites.
Topics: Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Boron Compounds; Chloroquine; Chlorpheniramine; Dibenzocycloheptenes; Drug Interactions; Drug Resistance, Multiple; Erythrocytes; Fluorescent Dyes; Gefitinib; Humans; Imatinib Mesylate; Mefloquine; Piperazines; Plasmodium falciparum; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Quinolines | 2013 |