Compounds > chloroquine

chloroquine and chlorambucil

chloroquine has been researched along with chlorambucil in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (26.67)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (40.00)	29.6817
2010's	5 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Mach, ES; Safonova, TN; Simonova, MV; Vasil'ev, VI	1
Andreev, T; Kozhukharova, M; Pilosof, T	1
Gandzha, IM; Shub, NI	1
Beresten', TI; Nasonova, VA; Sidel'nikova, SM; Tarasenkova, TA; Trofimova, TM	1
Konishi, M; Takahashi, K; Yoneda, K; Yoshimoto, E	1

Reviews

2 review(s) available for chloroquine and chlorambucil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Non-steroid therapy for sarcoidosis]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:9 Topics: Anti-Inflammatory Agents; Antimalarials; Azathioprine; Chlorambucil; Chloroquine; Cyclophosphamide; Cyclosporine; Humans; Methotrexate; Sarcoidosis; Steroids	2002

Trials

1 trial(s) available for chloroquine and chlorambucil

Article	Year
[Comparative evaluation of the treatment of Sjögren's syndrome with anti-rheumatic preparations]. Terapevticheskii arkhiv, 1988, Volume: 60, Issue:4 Topics: Adolescent; Adult; Anti-Inflammatory Agents; Chlorambucil; Chloroquine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Prednisolone; Sjogren's Syndrome	1988

Other Studies

12 other study(ies) available for chloroquine and chlorambucil

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
[Dynamics of circulating anti-tissue antibodies and titer of rheumatoid factor in rheumatoid polyarthritis under the effect of immunosuppressive drugs, antimalarials and gold salts]. Vutreshni bolesti, 1972, Volume: 11, Issue:3 Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antibody Formation; Antimalarials; Arthritis, Rheumatoid; Autoantibodies; Azathioprine; Chlorambucil; Chloroquine; Cyclophosphamide; Female; Gold; Humans; Immunosuppressive Agents; Male; Middle Aged; Rheumatoid Factor	1972
[Immunodepressants in the treatment of the major collagenoses]. Vrachebnoe delo, 1972, Volume: 11 Topics: Adolescent; Adult; Arthritis, Rheumatoid; Chlorambucil; Chloroquine; Female; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Male; Prednisolone	1972
[Treatment of rheumatoid arthritis with prolonged-action drugs]. Klinicheskaia meditsina, 1980, Volume: 58, Issue:8 Topics: Aminoquinolines; Arthritis, Rheumatoid; Chlorambucil; Chloroquine; Glucocorticoids; Gold; Humans; Immunosuppressive Agents; Penicillamine; Time Factors	1980