chloroquine has been researched along with caffeine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (33.33) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 7 (21.21) | 29.6817 |
| 2010's | 13 (39.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choo, YM; Doerksen, RJ; Gertsch, J; Hamann, MT; Jacob, MR; Khan, SI; Kudrimoti, S; Madgula, V; Mayer, AM; Odde, S; Peng, J; Pennaka, HK; Prasanna, S; Rao, KV; Tekwani, BL; Tu, LC; Wang, B | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Sen, S; Sinha, N | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cornelis, JJ; Hendrickx, B; Lakhanisky, T; Mouton, RF | 1 |
| Latarjet, R; Zajdela, F | 1 |
| Ayitey-Smith, E; Vartanian, GA | 1 |
| Gombe, S; Norman, C | 1 |
| Riley, TL; Yielding, KL; Yielding, LW | 1 |
| Okwuasaba, FK; Otubu, JA; Udoh, FV | 1 |
| Pearson, PL | 1 |
| Oldendorf, WH | 1 |
| Gaudin, D; Gregg, RS; Yielding, KL | 1 |
| Igarashi, SJ; Nakano, NI | 1 |
| Brown, J; Gaudin, D; Stabler, A; Yielding, KL | 1 |
| Gaudin, D; Yielding, KL | 1 |
| Adedoyin, A; Branch, RA; Frye, RF; Mauro, K | 1 |
| Sanderson, MJ; Tan, X | 1 |
| Abrial, C; Alvarez, JC; Brollo, M; Devillier, P; Faisy, C; Fayad-Kobeissi, S; Grassin-Delyle, S; Naline, E | 1 |
| Guo, D; Ji, G; Liu, QH; Peng, YB; Qin, G; Shen, J; Wei, MY; Wu, YF; Xu, JC | 1 |
1 review(s) available for chloroquine and caffeine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
32 other study(ies) available for chloroquine and caffeine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections.
Topics: Animals; Anti-Infective Agents; Carbazoles; Cerebellar Diseases; Indole Alkaloids; Mice; Microbial Sensitivity Tests; Molecular Structure; Neurogenic Inflammation; Porifera; Stereoisomerism; Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A serological study of removal of UV-induced photoproducts in the DNA of Tetrahymena pyriformis GL: influence of caffeine, quinacrine and chloroquine.
Topics: Animals; Caffeine; Chloroquine; DNA; DNA Repair; Immunologic Techniques; Photochemistry; Quinacrine; Tetrahymena pyriformis; Ultraviolet Rays | 1979 |
Inhibition of skin carcinogenesis in vivo by caffeine and other agents.
Topics: Animals; Caffeine; Cell Line; Chloroquine; DNA; DNA Repair; Female; Malondialdehyde; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Skin; Skin Neoplasms; Theophylline; Ultraviolet Rays | 1978 |
Dual action of chloroquine on frog's skeletal muscle contraction.
Topics: Acetylcholine; Animals; Caffeine; Carbachol; Chloroquine; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Muscle Contraction; Physostigmine; Potassium; Ranidae | 1975 |
Stimulatory effect of the lysosomal stabilizer, chloroquine, on the respiration and motility of fresh and aged bovine spermatozoa.
Topics: Animals; Caffeine; Cattle; Chloroquine; In Vitro Techniques; Male; Oxygen Consumption; Sperm Motility; Sperm Tail; Spermatozoa; Stimulation, Chemical; Theophylline; Tissue Preservation | 1975 |
Preliminary study of caffeine and chloroquine enhancement of x-ray induced birth defects.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Chloroquine; Drug Synergism; Female; Male; Mice; Mice, Inbred Strains; Radiation Effects; Teratogens | 1976 |
Mode of inhibitory actions of acute and chronic chloroquine administration on the electrically stimulated mouse diaphragm in vitro.
Topics: Animals; Caffeine; Calcium; Chloroquine; Dantrolene; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol; Male; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Procaine; Thiocyanates; Tubocurarine | 1990 |
The behavior of chromosomes.
Topics: Acridines; Caffeine; Chloroquine; Depression, Chemical; DNA; DNA Repair; DNA Replication; Floxuridine; Humans; Male; Meiosis; Sex Chromosomes; Spermatogenesis; Spermatozoa; Uracil; Urea | 1973 |
Brain uptake of metabolites and drugs following carotid arterial injections.
Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats | 1971 |
Inhibition of DNA repair replication by DNA binding drugs which sensitize cells to alkylating agents and X-rays.
Topics: Alkylating Agents; Caffeine; Chloroquine; Cyanides; Cyclophosphamide; Dinitrophenols; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Drug Combinations; Humans; Hydroxyurea; Injections, Intraperitoneal; Leukocyte Count; Lymphocytes; Protein Binding; Quinacrine; Quinolines; Radiation Effects; Radiation-Sensitizing Agents; Thymidine; Tritium; Ultraviolet Rays | 1972 |
Molecular interactions of pyrimidines, purines, and some other heteroaromatic compounds in aqueous media.
Topics: Adenine; Caffeine; Chemical Phenomena; Chemistry; Chloroquine; Drug Stability; Guanidines; Hypoxanthines; Nucleosides; Purines; Pyrimidines; Quinoxalines; Solubility; Theophylline; Tritium; Water | 1970 |
The effect of DNA repair inhibitors on e response of tumors treated with x-ray and alkylating agents.
Topics: Alkylating Agents; Animals; Bone Marrow; Caffeine; Chloroquine; Cricetinae; Cyclophosphamide; DNA; Leukocyte Count; Leukocytes; Melanoma; Nitrogen Mustard Compounds; Phenylalanine; Plasmacytoma | 1971 |
Response of a "resistant" plasmacytoma to alkylating agents and x-ray in combination with the "excision" repair inhibitors caffeine and chloroquine.
Topics: Animals; Caffeine; Chloroquine; Cricetinae; Cyclophosphamide; Depression, Chemical; DNA, Neoplasm; Mechlorethamine; Neoplasms, Experimental; Plasmacytoma | 1969 |
Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail.
Topics: Adult; Analysis of Variance; Antimalarials; Caffeine; Chloroquine; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Administration Schedule; Drug Interactions; Humans; Isoenzymes; Male; Phenotype | 1998 |
Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity.
Topics: Airway Resistance; Animals; Bronchodilator Agents; Caffeine; Calcium Channel Blockers; Calcium Signaling; Chloroquine; Drug Resistance; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lung; Mice; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Ryanodine; Taste | 2014 |
The expression and relaxant effect of bitter taste receptors in human bronchi.
Topics: Adult; Aged; Aged, 80 and over; Bronchi; Bronchoconstriction; Bronchodilator Agents; Caffeine; Chloroquine; Female; Humans; Male; Middle Aged; Piperidines; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Strychnine; Taste | 2013 |
Chloroquine Inhibits Ca(2+) Signaling in Murine CD4(+) Thymocytes.
Topics: Animals; Caffeine; Calcium; Calcium Signaling; CD4-Positive T-Lymphocytes; Cells, Cultured; Chloroquine; Gene Expression Regulation; Male; Mice; Pyrazoles; Thapsigargin; Thymocytes | 2015 |