chloroquine has been researched along with brefeldin a in 72 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 46 (63.89) | 18.2507 |
| 2000's | 23 (31.94) | 29.6817 |
| 2010's | 3 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Gapud, CP; Keil, W; Reiss, CS | 1 |
| Chakrabarti, D; Ghosh, SK | 1 |
| Buxbaum, JD; Caporaso, GL; Gandy, SE; Greengard, P | 1 |
| Hatch, GM; Vance, DE | 1 |
| Heldin, CH; Ostman, A; Thyberg, J; Westermark, B | 1 |
| Kaye, PM; Lang, T | 1 |
| Bertoletti, A; Cavalli, A; Chisari, FV; Fiaccadori, F; Fowler, P; Guilhot, S; Margolskee, RF; Moss, B; Penna, A; Valli, A | 1 |
| Carson, GR; Kane, LP; Terhorst, C; Wileman, T | 1 |
| Bachhawat, AK; Pillai, S | 1 |
| Hofmann, WJ; Koch, N; Moldenhauer, G; Möller, P | 1 |
| Biddison, WE; Klausner, RD; Nuchtern, JG | 1 |
| Chen, BP; Madrigal, A; Parham, P | 1 |
| Jaraquemada, D; Long, EO; Marti, M | 1 |
| al-Jaufy, AY; Jackson, MP; King, SR | 1 |
| Andersson, LM; Warburton, MJ | 1 |
| Bächi, T; Berger, EG; Bosshart, H; Grimm, K; Kleene, R; Watzele, M | 1 |
| Adorini, L; Busch, R; Drexler, J; Fuchs, S; Hämmerling, GJ; Momburg, F; Post, M | 1 |
| Cerundolo, V; Elliott, T; Townsend, A; Willis, A | 1 |
| Kovacsovics-Bankowski, M; Rock, KL | 1 |
| Hitzel, C; Koch, N; van Endert, P | 1 |
| Mendez, AJ | 1 |
| Abdel Motal, UM; Jondal, M; Siddiqi, AR; Zhou, MX | 1 |
| Andrews, JV; Eberlein, TJ; Goedegebuure, PS; Peoples, GE; Schoof, DD | 1 |
| Hatch, GM; Oskin, A; Vance, DE | 1 |
| Curran, PK; Fishman, PH; Orlandi, PA | 1 |
| Hirata, K; Ikeda, H; Kikuchi, K; Ohta, M; Sato, N; Takahashi, S; Ueda, D; Wada, Y | 1 |
| Getz, GS; Reardon, CA; Ye, SQ | 1 |
| Hoidal, JR; Marshall, BC; Rao, GV; Rao, NV | 1 |
| Barrett, AJ; Couriel, D; Dermime, S; Hensel, N; Jiang, YZ; Mavroudis, D; Molldrem, J | 1 |
| Gross, HJ; Merling, A; Moldenhauer, G; Schwartz-Albiez, R | 1 |
| Deng, P; Pattengale, PK; Rettenmier, CW | 1 |
| Barbieri, JT; Finck-Barbançon, V | 1 |
| Barret, A; Muller, L; Picart, R; Tougard, C | 1 |
| Dranoff, G; Reznikoff, G; Rock, KL; Shen, Z | 1 |
| Batuman, V; Guan, S | 1 |
| Freeman, DA; Porpaczy, Z; Tomasek, JJ | 1 |
| Bakke, O; Stang, E | 1 |
| Becich, MJ; Gau, JT; Grove, ML; Krill, D; Salter, RD | 1 |
| Breitschopf, K; Ciechanover, A; Gautschi, I; Ishikawa, T; Rotin, D; Schild, L; Staub, O | 1 |
| Balaji, KN; Boom, WH | 1 |
| DeLuca, A; Eckhardt, AE; Hill, RL; Perez-Vilar, J | 1 |
| Bortzov, F; Budker, V; Gurevich, V; Hagstrom, JE; Wolff, JA | 1 |
| Ishiura, S; Kinouchi, T; Kouchi, Z; Sorimachi, H; Suzuki, K | 1 |
| Caselmann, WH; Diepolder, HM; Gerlach, JT; Gr ner, N; Jung, MC; Pape, GR; Ries, G; Schlicht, HJ | 1 |
| Borowski, L; Fan, Z; Huang, XL; Rinaldo, CR; Wilson, CC; Zheng, L | 1 |
| Alonso, MA; Puertollano, R | 1 |
| Buschard, K; Ekblond, A; Fredman, P; Halldner, L; Horn, T; Josefsen, K; Mânsson, JE; Osterbye, T; Rynmark, BM | 1 |
| Bang, KW; Blanchette, VS; Freedman, J; Semple, JW; Speck, ER | 1 |
| Chang, JE; Dannies, PS; Lee, MS; Zhu, YL | 1 |
| Ostrand-Rosenberg, S; Qi, L | 1 |
| Früh, K; Gruhler, A; Peterson, PA | 1 |
| Blum, JS; Pathak, SS | 1 |
| McConnell, HM; Vacchino, JF | 1 |
| Fujii, Y; Fujimoto, K; Fujita, J; Fujita, T; Masunaga, Y; Mayumi, T; Mori, K; Nakagawa, S; Nakanishi, T; Okada, N; Saito, T; Tanaka, K; Yamamoto, A | 1 |
| Fouchier, RA; Nieuwkoop, NJ; Osterhaus, AD; Rimmelzwaan, GF; Voeten, JT | 1 |
| Harutyunyan, K; Holmes, RK; Joenje, H; Shah, M; Youssoufian, H | 1 |
| Engström, A; Larsson, M; Rask, L; Sakwe, AM | 1 |
| Harada, M; Morita, A; Nakayama, E; Ono, T; Ota, S; Uenaka, A | 1 |
| Boom, WH; Fournié, JJ; Harding, CV; Rojas, RE; Torres, M | 1 |
| Beacock-Sharp, H; Donachie, AM; Mowat, AM; Robson, NC | 1 |
| Blomqvist, M; Buschard, K; Fredman, P; Horn, T; Månsson, JE; Osterbye, T | 1 |
| Arai, H; Arita, M; Horiguchi, M; Inoue, K; Kaempf-Rotzoll, DE; Tsujimoto, M | 1 |
| Abastado, JP; Almunia, C; Babon, A; Beaumelle, B; Boccaccio, C; Gelb, MH; Gillet, D; Maillère, B; Ménez, A; Salcedo, M | 1 |
| Braun, NA; Fazio, S; Hasty, AH; Linton, MF; Mohler, PJ; Su, YR; Swift, LL; Weisgraber, KH; Yancey, PG | 1 |
| Gerelchuluun, T; Han, K; Im, SA; Kim, K; Lee, CK; Lee, YH; Lee, YR; Park, JS; Song, S | 1 |
| Donachie, AM; Mowat, AM; Robson, NC | 1 |
| Cabral, HR; Novak, IT | 1 |
| Belizaire, R; Unanue, ER | 1 |
| Cowman, AF; de Koning-Ward, T; Ehlgen, F; Pham, JS; Ralph, SA | 1 |
| Choudhury, A; Inamdar, SM; Jung, JJ; Nihalani, D; Tiwari, A | 1 |
| Crowley, LC; McKenna, SL; Nyhan, MJ; O'Donovan, TR | 1 |
72 other study(ies) available for chloroquine and brefeldin a
| Article | Year |
|---|---|
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Newly synthesized class II MHC chains are required for VSV G presentation to CTL clones.
Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Antigens, Viral; Brefeldin A; Chloroquine; Clone Cells; Cyclopentanes; Emetine; Glycoproteins; Histocompatibility Antigens Class II; Lymphocyte Cooperation; Membrane Glycoproteins; Mice; Recombinant Proteins; Solubility; T-Lymphocytes, Cytotoxic; Vesicular stomatitis Indiana virus; Viral Envelope Proteins | 1992 |
Induction of syngeneic cytotoxic T lymphocytes against a B cell tumor. III. MHC class I-restricted CTL recognizes the processed form(s) of idiotype.
Topics: Animals; Antigen-Presenting Cells; Brefeldin A; Chloroquine; Cyclopentanes; Histocompatibility Antigens Class I; Immunoglobulin Idiotypes; Lymphoma, B-Cell; Mice; Mice, Inbred BALB C; Receptors, Antigen, B-Cell; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic | 1992 |
Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.
Topics: Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Bacterial Agents; Autoradiography; Brefeldin A; Chloroquine; Cyclopentanes; Glycosylation; Kinetics; Methionine; Molecular Weight; Monensin; Organelles; PC12 Cells; Protein Processing, Post-Translational; Sulfur Radioisotopes; Time Factors | 1992 |
Stimulation of sphingomyelin biosynthesis by brefeldin A and sphingomyelin breakdown by okadaic acid treatment of rat hepatocytes.
Topics: Animals; Brefeldin A; Chloroquine; Colforsin; Cyclopentanes; Ethers, Cyclic; Kinetics; Liver; Male; Okadaic Acid; Phosphatidylcholines; Rats; Rats, Inbred Strains; Sphingomyelins | 1992 |
PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly.
Topics: Animals; Brefeldin A; Chloroquine; CHO Cells; Cricetinae; Cyclopentanes; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Golgi Apparatus; Lysosomes; Microscopy, Immunoelectron; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Transfection | 1992 |
Presentation of Leishmania donovani promastigotes occurs via a brefeldin A-sensitive pathway.
Topics: Animals; Antigen-Presenting Cells; Antigens, Protozoan; Brefeldin A; CD4-Positive T-Lymphocytes; Chloroquine; Cyclopentanes; Histocompatibility Antigens Class II; Leishmania donovani; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Peritoneal Cavity | 1991 |
Hepatitis B virus (HBV)-specific cytotoxic T-cell (CTL) response in humans: characterization of HLA class II-restricted CTLs that recognize endogenously synthesized HBV envelope antigens.
Topics: Ammonium Chloride; Antigens, Viral; Antiviral Agents; Brefeldin A; CD4 Antigens; Chloroquine; Clone Cells; Cyclopentanes; Hepatitis B; Hepatitis B virus; HLA-D Antigens; Humans; Recombination, Genetic; T-Lymphocytes, Cytotoxic; Vaccinia virus; Viral Envelope Proteins | 1992 |
Depletion of cellular calcium accelerates protein degradation in the endoplasmic reticulum.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Brefeldin A; Calcimycin; Calcium; Calcium-Transporting ATPases; CD3 Complex; Cell Line; Chloroquine; Cricetinae; Cyclopentanes; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Humans; In Vitro Techniques; Lysosomes; Protein Processing, Post-Translational; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Interleukin-2; Secretory Rate; Terpenes; Thapsigargin; Transfection | 1991 |
Distinct intracellular fates of membrane and secretory immunoglobulin heavy chains in a pre-B cell line.
Topics: Ammonium Chloride; Animals; B-Lymphocytes; Brefeldin A; Cell Line, Transformed; Chloroquine; Cyclopentanes; Immunoglobulin A, Secretory; Immunoglobulin Heavy Chains; Immunoglobulin Isotypes; Kinetics; Lysosomes; Monensin; Receptors, Antigen, B-Cell | 1991 |
Rapid intracellular pathway gives rise to cell surface expression of the MHC class II-associated invariant chain (CD74).
Topics: Antigens, Differentiation, B-Lymphocyte; Antigens, Surface; Biological Transport; Brefeldin A; Chloroquine; Cyclopentanes; Histocompatibility Antigens Class II; Humans; Lymphoma, B-Cell; Microscopy, Immunoelectron; Tumor Cells, Cultured | 1991 |
Class II MHC molecules can use the endogenous pathway of antigen presentation.
Topics: Antigen-Presenting Cells; Biological Transport; Brefeldin A; CD4-Positive T-Lymphocytes; Chloroquine; Cyclopentanes; Cytoplasm; Histocompatibility Antigens Class I; HLA-D Antigens; Humans; Immunity, Cellular; In Vitro Techniques; Influenza A virus; Major Histocompatibility Complex; T-Lymphocytes, Cytotoxic; Viral Matrix Proteins | 1990 |
Cytotoxic T cell recognition of an endogenous class I HLA peptide presented by a class II HLA molecule.
Topics: Anti-Bacterial Agents; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Brefeldin A; CD4 Antigens; CD8 Antigens; Cell Line; Chloroquine; Cyclopentanes; Cytotoxicity, Immunologic; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Leukocytes; Peptide Fragments; T-Lymphocytes, Cytotoxic | 1990 |
An endogenous processing pathway in vaccinia virus-infected cells for presentation of cytoplasmic antigens to class II-restricted T cells.
Topics: Anti-Bacterial Agents; Brefeldin A; Cell Line; Chloroquine; Cyclopentanes; Cytotoxicity, Immunologic; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Influenza A virus; Kinetics; Recombination, Genetic; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Vaccinia virus; Viral Matrix Proteins | 1990 |
Purification and characterization of a Shiga toxin A subunit-CD4 fusion protein cytotoxic to human immunodeficiency virus-infected cells.
Topics: Ammonium Chloride; Animals; Bacterial Toxins; Base Sequence; Brefeldin A; CD4 Antigens; Cell Compartmentation; Cell Line; Chlorocebus aethiops; Chloroquine; Cyclopentanes; Cytotoxins; DNA Primers; HIV Infections; Humans; In Vitro Techniques; Molecular Sequence Data; Recombinant Fusion Proteins; Shiga Toxins; Vero Cells | 1995 |
Intracellular degradation of type I collagen and fibronectin in human lung fibroblasts: evidence against degradation in pre-lysosomal compartments.
Topics: 2,2'-Dipyridyl; Biological Transport; Brefeldin A; Canavanine; Cell Line; Cell Membrane Permeability; Chloroquine; Collagen; Cyclopentanes; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Fibroblasts; Fibronectins; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydroxybenzoates; Lung; Monensin; Organelles; Protein Folding; Protein Synthesis Inhibitors | 1995 |
Double immunofluorescent staining of alpha 2,6 sialyltransferase and beta 1,4 galactosyltransferase in monensin-treated cells: evidence for different Golgi compartments?
Topics: Antibodies, Monoclonal; Base Sequence; beta-D-Galactoside alpha 2-6-Sialyltransferase; Brefeldin A; Cell Compartmentation; Chloroquine; Cyclopentanes; Fluorescent Antibody Technique; Golgi Apparatus; HeLa Cells; Humans; Molecular Sequence Data; Monensin; N-Acetyllactosamine Synthase; Nocodazole; Sialyltransferases; Staining and Labeling; Tumor Cells, Cultured | 1993 |
Epitope-specific enhancement of antigen presentation by invariant chain.
Topics: Animals; Antigen-Presenting Cells; Antigens, Differentiation, B-Lymphocyte; Brefeldin A; Cells, Cultured; Chloroquine; Cyclopentanes; Epitopes; HeLa Cells; Histocompatibility Antigens Class II; Humans; Hybridomas; Rats | 1993 |
Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum.
Topics: Amino Acid Sequence; Animals; Antigen Presentation; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Biological Transport; Brefeldin A; Cell Compartmentation; Chloroquine; Cyclopentanes; Endoplasmic Reticulum; H-2 Antigens; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Immunodominant Epitopes; L Cells; Mice; Mice, Inbred CBA; Molecular Sequence Data; Peptide Fragments; Tosyllysine Chloromethyl Ketone | 1995 |
A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules.
Topics: Amino Acid Sequence; Animals; Antigen Presentation; Antigens; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Brefeldin A; Cell Line; Chloroquine; Cyclopentanes; Cysteine Endopeptidases; Cytosol; Histocompatibility Antigens Class I; Macrophages; Mice; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Ovalbumin; Phagocytosis; Phagosomes; Plant Proteins; Proteasome Endopeptidase Complex; Ribosome Inactivating Proteins, Type 1 | 1995 |
Acquisition of peptides by MHC class II polypeptides in the absence of the invariant chain.
Topics: Amino Acid Sequence; Animals; Antigen Presentation; Antigens, Differentiation, B-Lymphocyte; Brefeldin A; Cell Line; Chloroquine; Cyclopentanes; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Leupeptins; Molecular Sequence Data; Peptides; Precipitin Tests; Protein Binding; Rats; Sodium Dodecyl Sulfate; Transfection; Tumor Cells, Cultured | 1995 |
Monensin and brefeldin A inhibit high density lipoprotein-mediated cholesterol efflux from cholesterol-enriched cells. Implications for intracellular cholesterol transport.
Topics: Ammonium Chloride; Animals; Aorta, Abdominal; Biological Transport; Brefeldin A; Cells, Cultured; Chloroquine; Cholesterol; Cyclopentanes; Dose-Response Relationship, Drug; Fibroblasts; Humans; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Male; Models, Biological; Monensin; Muscle, Smooth, Vascular; Nigericin; Protein Synthesis Inhibitors; Skin; Sterols; Swine | 1995 |
Regulation of MHC class I membrane expression by beta 2-microglobulin.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antigens, Surface; beta 2-Microglobulin; Brefeldin A; Chloroquine; Cyclopentanes; Flow Cytometry; Histocompatibility Antigens Class I; Humans; Mice; Molecular Sequence Data; Peptides; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured; Up-Regulation | 1993 |
HLA-A2 presents shared tumor-associated antigens derived from endogenous proteins in ovarian cancer.
Topics: Antigen Presentation; Antigens, Neoplasm; Brefeldin A; Chloroquine; Cyclopentanes; Cytotoxicity, Immunologic; Female; HLA-A2 Antigen; Humans; Lymphocytes, Tumor-Infiltrating; Ovarian Neoplasms; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1993 |
Involvement of the lysosome in the catabolism of intracellular lysophosphatidylcholine and evidence for distinct pools of lysophosphatidylcholine.
Topics: Albumins; Animals; Brefeldin A; Chloroquine; Choline; Cyclopentanes; Cytidine Diphosphate Choline; Liver; Lysophosphatidylcholines; Lysosomes; Methionine; Methylation; Phosphatidylcholines; Rats; Tritium | 1993 |
Brefeldin A blocks the response of cultured cells to cholera toxin. Implications for intracellular trafficking in toxin action.
Topics: Adenocarcinoma; Adenylyl Cyclases; Animals; Biological Transport; Brefeldin A; Cell Line; Chloroquine; Cholera Toxin; Colonic Neoplasms; Cyclic AMP; Cyclopentanes; Enzyme Activation; Glioma; Golgi Apparatus; Humans; Isoproterenol; Kinetics; Monensin; Mycotoxins; Rats; Time Factors; Tumor Cells, Cultured | 1993 |
Brefeldin A blocks the cytotoxicity of T cell receptor alpha/beta and gamma/delta cytotoxic T lymphocyte clones reacting against human autologous cancer cells.
Topics: Brefeldin A; Chloroquine; Colchicine; Cycloheximide; Cyclopentanes; Cytotoxicity Tests, Immunologic; Humans; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1993 |
Inhibition of apolipoprotein E degradation in a post-Golgi compartment by a cysteine protease inhibitor.
Topics: Albumins; Ammonium Chloride; Animals; Apolipoproteins E; Brefeldin A; Calcium; Cathepsin B; Cathepsin L; Cathepsins; Chloroquine; CHO Cells; Cricetinae; Cyclopentanes; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Golgi Apparatus; Humans; Kinetics; Leupeptins; Molecular Sequence Data; Transfection; Tumor Cells, Cultured | 1993 |
Biosynthesis and processing of proteinase 3 in U937 cells. Processing pathways are distinct from those of cathepsin G.
Topics: Amino Acid Sequence; Ammonium Chloride; Animals; Autoradiography; Brefeldin A; Cathepsin C; Cathepsin G; Cathepsins; Cell Line; Chloroquine; Cricetinae; Cyclopentanes; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Electrophoresis, Polyacrylamide Gel; Enzyme Precursors; Humans; Isoleucine; Methionine; Molecular Sequence Data; Myeloblastin; Neutrophils; Peptide Fragments; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Sequence Homology, Amino Acid; Serine Endopeptidases; Sulfur Radioisotopes; Tritium | 1996 |
Alloreactive CD4+ T lymphocytes can exert cytotoxicity to chronic myeloid leukaemia cells processing and presenting exogenous antigen.
Topics: Bone Marrow Transplantation; Brefeldin A; CD4-Positive T-Lymphocytes; Chloroquine; Cyclopentanes; Cytotoxicity, Immunologic; fas Receptor; Graft vs Host Reaction; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Protein Synthesis Inhibitors | 1996 |
Ecto-sialyltransferase of human B lymphocytes reconstitutes differentiation markers in the presence of exogenous CMP-N-acetyl neuraminic acid.
Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; beta-D-Galactoside alpha 2-6-Sialyltransferase; beta-Galactoside alpha-2,3-Sialyltransferase; Brefeldin A; Chloroquine; Culture Media, Conditioned; Cyclopentanes; Cytidine Monophosphate N-Acetylneuraminic Acid; Enzyme Inhibitors; Glycosylation; HLA-D Antigens; Humans; Membrane Glycoproteins; Neoplasm Proteins; Neuraminic Acids; Protein Processing, Post-Translational; Receptors, Antigen, B-Cell; Receptors, Transferrin; Sialyltransferases; Tumor Cells, Cultured | 1996 |
Structural requirements for the ectodomain cleavage of human cell surface macrophage colony-stimulating factor.
Topics: 3T3 Cells; Allosteric Regulation; Amino Acid Sequence; Animals; Brefeldin A; Calcimycin; Cell Membrane; Chloroquine; Cyclopentanes; DNA, Complementary; Humans; Macrophage Colony-Stimulating Factor; Methionine; Mice; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Conformation; Protein Synthesis Inhibitors; Recombinant Proteins; Sequence Deletion; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Preferential processing of the S1 subunit of pertussis toxin that is bound to eukaryotic cells.
Topics: Animals; Biological Transport; Brefeldin A; Cell Compartmentation; Chloroquine; CHO Cells; Cricetinae; Cyclopentanes; Dogs; Endosomes; Eukaryotic Cells; Iodine Radioisotopes; Isotope Labeling; Models, Biological; Nocodazole; Pertussis Toxin; Pronase; Protein Conformation; Receptors, Cell Surface; Swine; Virulence Factors, Bordetella | 1996 |
Proteolytic processing of sulfated secretogranin II in the trans-Golgi network of GH3B6 prolactin cells.
Topics: Animals; Brefeldin A; Chloroquine; Chromogranins; Cyclopentanes; Golgi Apparatus; Hydrogen-Ion Concentration; Neuropeptides; Neurosecretory Systems; Prolactin; Proteins; Sulfates; Thyrotropin-Releasing Hormone | 1997 |
Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules.
Topics: Animals; Antigen Presentation; Antigens, Surface; Bone Marrow Cells; Brefeldin A; Cell Line; Cell Separation; Chloroquine; Clone Cells; Cyclopentanes; Cysteine Endopeptidases; Cytochalasin B; Dendritic Cells; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Ovalbumin; Particle Size; Phagocytosis; Proteasome Endopeptidase Complex | 1997 |
Receptor-mediated endocytosis of immunoglobulin light chains by renal proximal tubule cells.
Topics: Ammonium Chloride; Animals; Brefeldin A; Cattle; Cell Line; Cell Line, Transformed; Cells, Cultured; Chloroquine; Cyclopentanes; Endocytosis; Enzyme Inhibitors; Female; Humans; Hypertonic Solutions; Immunoglobulin Light Chains; Iodine Radioisotopes; Kidney Tubules, Proximal; Kinetics; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Simian virus 40; Sucrose; Temperature | 1997 |
Internalized plasma membrane cholesterol passes through an endosome compartment that is distinct from the acid vesicle-lysosome compartment.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Brefeldin A; Bucladesine; Cell Fractionation; Cell Membrane; Chloroquine; Cholesterol; Cholesterol Esters; Cholesterol, LDL; Cyclopentanes; Endosomes; Fluorescent Dyes; Golgi Apparatus; Leydig Cell Tumor; Lysosomes; Mice; Progesterone; Protein Synthesis Inhibitors; Sphingosine; Tumor Cells, Cultured | 1997 |
MHC class II-associated invariant chain-induced enlarged endosomal structures: a morphological study.
Topics: Adenine; Antigens, CD; Brefeldin A; Cell Line; Chloroquine; Cyclopentanes; Endocytosis; Endosomes; Fibroblasts; HLA-DR alpha-Chains; HLA-DR Antigens; Humans; Immunohistochemistry; Leupeptins; Lysosomal Membrane Proteins; Lysosomes; Macromolecular Substances; Membrane Glycoproteins; Receptor, IGF Type 2; Recombinant Proteins; Transfection | 1997 |
The biosynthesis and secretion of prostate-specific antigen in LNCaP cells.
Topics: 1-Deoxynojirimycin; Biological Transport; Brefeldin A; Chloroquine; Cyclopentanes; Dihydrotestosterone; Dithiothreitol; Endoplasmic Reticulum; Golgi Apparatus; Humans; Male; Neoplasm Proteins; Pilocarpine; Precipitin Tests; Prostate-Specific Antigen; Protein Synthesis Inhibitors; Saponins; Tumor Cells, Cultured; Tunicamycin | 1997 |
Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; Brefeldin A; Calcium-Binding Proteins; Cell Line; Chloroquine; Cyclopentanes; Cysteine Endopeptidases; Dogs; Endosomal Sorting Complexes Required for Transport; Endosomes; Epithelial Sodium Channels; Epithelium; Half-Life; Ion Channel Gating; Ion Transport; Ligases; Lysosomes; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Nedd4 Ubiquitin Protein Ligases; Nuclear Magnetic Resonance, Biomolecular; Oocytes; Point Mutation; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Conformation; Protein Processing, Post-Translational; Rats; Recombinant Fusion Proteins; Sodium; Sodium Channels; Transfection; Ubiquitin-Protein Ligases; Ubiquitins; Up-Regulation; Xenopus laevis; Xenopus Proteins | 1997 |
Processing of Mycobacterium tuberculosis bacilli by human monocytes for CD4+ alphabeta and gammadelta T cells: role of particulate antigen.
Topics: Ammonium Chloride; Antigen Presentation; Antigens, Bacterial; Brefeldin A; CD4-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Chloroquine; Cyclopentanes; Cytochalasin D; Cytotoxicity Tests, Immunologic; Formaldehyde; HLA-DR Antigens; Humans; Monocytes; Mycobacterium tuberculosis; Phagocytosis; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta | 1998 |
Porcine submaxillary mucin forms disulfide-linked multimers through its amino-terminal D-domains.
Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Chloroquine; COS Cells; Cyclopentanes; Disulfides; Glycosylation; Golgi Apparatus; Hydrogen-Ion Concentration; Macrolides; Molecular Sequence Data; Monensin; Mucins; Protein Conformation; Proton-Translocating ATPases; Recombinant Proteins; Submandibular Gland; Swine; Transfection | 1998 |
pH-sensitive, cationic liposomes: a new synthetic virus-like vector.
Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Brefeldin A; Cations; Chloroquine; Cyclopentanes; Endosomes; Genetic Vectors; Hydrogen-Ion Concentration; Liposomes; Macrolides; Mice; Transfection | 1996 |
The deletion of the C-terminal tail and addition of an endoplasmic reticulum targeting signal to Alzheimer's amyloid precursor protein change its localization, secretion, and intracellular proteolysis.
Topics: Adenovirus Early Proteins; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biotinylation; Brefeldin A; Chloroquine; COS Cells; Endoplasmic Reticulum; Fluorescent Antibody Technique; Humans; Kinetics; Microscopy, Fluorescence; Monensin; Protein Sorting Signals; Recombinant Fusion Proteins; Transfection | 1998 |
Differential antigen-processing pathways of the hepatitis B virus e and core proteins.
Topics: Amino Acid Sequence; Antigen-Presenting Cells; Brefeldin A; CD4-Positive T-Lymphocytes; Chloroquine; Clone Cells; Epitopes; Hepatitis B Core Antigens; Hepatitis B e Antigens; HLA-D Antigens; Humans; Lymphocyte Activation; Molecular Sequence Data; Recombinant Proteins; T-Lymphocytes; Vaccinia virus | 1999 |
Delivery of liposome-encapsulated HIV type 1 proteins to human dendritic cells for stimulation of HIV type 1-specific memory cytotoxic T lymphocyte responses.
Topics: Adult; Antigen Presentation; Antiviral Agents; Brefeldin A; Cells, Cultured; Chloroquine; Cohort Studies; Dendritic Cells; HIV-1; Homosexuality, Male; Humans; Immunologic Memory; Liposomes; Male; T-Lymphocytes, Cytotoxic; Viral Proteins | 1999 |
MAL, an integral element of the apical sorting machinery, is an itinerant protein that cycles between the trans-Golgi network and the plasma membrane.
Topics: Ammonium Chloride; Animals; Biological Transport; Biotinylation; Brefeldin A; Cell Line; Cell Membrane; Chloroquine; COS Cells; Dogs; Endosomes; Flow Cytometry; Fluorescent Antibody Technique; Glycosylation; Golgi Apparatus; Membrane Transport Proteins; Monensin; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Neuraminidase; Nocodazole; Oligopeptides; Peptides; Proteolipids; Recombinant Proteins; Transfection; Transferrin | 1999 |
The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking.
Topics: Animals; Biological Transport; Brefeldin A; Carboxylic Acids; Chloroquine; Fumonisins; Galactosyltransferases; Ganglioside Galactosyltransferase; Glycosphingolipids; Insulin; Islets of Langerhans; Male; Microscopy, Electron; Rats; Rats, Inbred Lew; RNA, Messenger; Sulfoglycosphingolipids; Sulfotransferases | 2000 |
Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MHC antigens.
Topics: Ammonium Chloride; Animals; Antibody Specificity; Antigen Presentation; Antigen-Presenting Cells; Blood Donors; Blood Platelets; Brefeldin A; Chloroquine; Colchicine; Cytosol; Endocytosis; Endosomes; Enzyme Activation; Female; H-2 Antigens; Immunoglobulin G; Interleukin-4; Isoantibodies; Leupeptins; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microtubules; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Transfusion; T-Lymphocytes, Helper-Inducer; Tubulin | 2000 |
Acquisition of Lubrol insolubility, a common step for growth hormone and prolactin in the secretory pathway of neuroendocrine cells.
Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Chloroquine; COS Cells; Dinitrobenzenes; Endoplasmic Reticulum; Epidermal Growth Factor; Estradiol; Human Growth Hormone; Hydrogen-Ion Concentration; Insulin; Macrolides; Mutation; Pituitary Gland; Polyethylene Glycols; Prolactin; Protein Transport; Rats; Secretory Vesicles; Solubility; Substrate Specificity; Tumor Cells, Cultured; Ultracentrifugation | 2001 |
MHC class II presentation of endogenous tumor antigen by cellular vaccines depends on the endocytic pathway but not H2-M.
Topics: Acetylcysteine; Animals; Antigen Presentation; Antigen-Presenting Cells; Antigens, Neoplasm; Antimalarials; Brefeldin A; CD4-Positive T-Lymphocytes; Chloroquine; Coculture Techniques; Cysteine Proteinase Inhibitors; Cytosol; Dose-Response Relationship, Drug; Endocytosis; Endoplasmic Reticulum; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Genes, MHC Class II; Humans; Hybridomas; Leupeptins; Major Histocompatibility Complex; Mice; Muramidase; Plasmids; Primaquine; Protein Synthesis Inhibitors; Protein Transport; Ribonucleases; Transfection; Tumor Cells, Cultured | 2000 |
Human cytomegalovirus immediate early glycoprotein US3 retains MHC class I molecules by transient association.
Topics: Anti-Bacterial Agents; Antigen Presentation; Antimalarials; Brefeldin A; CD4 Antigens; CD8 Antigens; Cell Adhesion Molecules, Neuronal; Cell Line; Cell Separation; Chloroquine; Cytoplasm; Cytosol; Endoplasmic Reticulum; Epitopes; Flow Cytometry; Glycoproteins; Golgi Apparatus; GPI-Linked Proteins; HeLa Cells; Hexosaminidases; Histocompatibility Antigens Class I; Humans; Immediate-Early Proteins; Lysosomes; Macrolides; Membrane Proteins; Microscopy, Confocal; Precipitin Tests; Protein Transport; Puromycin; Time Factors; Transfection | 2000 |
Endocytic recycling is required for the presentation of an exogenous peptide via MHC class II molecules.
Topics: Anti-Bacterial Agents; Antigen Presentation; Antigens, Viral; Biotinylation; Brefeldin A; Cell Line; Chloroquine; Deoxyglucose; Endocytosis; Genes, MHC Class II; Hemagglutinin Glycoproteins, Influenza Virus; HLA-DR Antigens; HLA-DR4 Antigen; HLA-DRB1 Chains; Humans; Macrolides; Macromolecular Substances; Peptide Fragments; Protein Transport; Serum Albumin; Severe Combined Immunodeficiency; Sodium Azide; Transfection | 2000 |
Peptide binding to active class II MHC protein on the cell surface.
Topics: Amino Acid Sequence; Animals; Antigen Presentation; Biotinylation; Brefeldin A; Cell Membrane; Chloroquine; CHO Cells; Cricetinae; Cytochrome c Group; Histocompatibility Antigens Class II; Kinetics; Mice; Molecular Sequence Data; Moths; Peptide Fragments; Protein Binding; Protein Transport; Sodium Azide; Solubility; Transfection | 2001 |
Effects of lipofectin-antigen complexes on major histocompatibility complex class I-restricted antigen presentation pathway in murine dendritic cells and on dendritic cell maturation.
Topics: Acetylcysteine; Animals; Antigen Presentation; Antigens; Brefeldin A; Cell Line; Cell Survival; Chloroquine; Cytochalasin B; Dendritic Cells; Histocompatibility Antigens Class I; Major Histocompatibility Complex; Mice; Ovalbumin; Phosphatidylethanolamines; Time Factors | 2001 |
Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells.
Topics: Acetylcysteine; Antigen Presentation; B-Lymphocytes; Brefeldin A; Chloroquine; Endosomes; Enzyme Inhibitors; Hematopoietic Stem Cells; Histocompatibility Antigens Class I; Humans; Influenza A virus; Major Histocompatibility Complex; Nucleocapsid Proteins; Nucleoproteins; Peptide Fragments; RNA-Binding Proteins; Viral Core Proteins | 2001 |
Correction of cross-linker sensitivity of Fanconi anemia group F cells by CD33-mediated protein transfer.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brefeldin A; Cell Membrane; Cell Nucleus; Chloroquine; Cross-Linking Reagents; Endosomes; Escherichia coli; Fanconi Anemia; Fanconi Anemia Complementation Group F Protein; Gene Expression; Gene Targeting; Golgi Apparatus; Half-Life; HeLa Cells; Hematopoietic Stem Cells; Histidine; Humans; Lymphocytes; Recombinant Fusion Proteins; RNA-Binding Proteins; Sialic Acid Binding Ig-like Lectin 3; Transfection | 2001 |
Biosynthesis and secretion of parathyroid hormone are sensitive to proteasome inhibitors in dispersed bovine parathyroid cells.
Topics: Acetylcysteine; Animals; Brefeldin A; Calpain; Cattle; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; HSP70 Heat-Shock Proteins; Multienzyme Complexes; Parathyroid Glands; Parathyroid Hormone; Proteasome Endopeptidase Complex; Protein Precursors | 2002 |
Cellular processing of a multibranched lysine core with tumor antigen peptides and presentation of peptide epitopes recognized by cytotoxic T lymphocytes on antigen-presenting cells.
Topics: Animals; Antigen Presentation; Antigen-Presenting Cells; Antigens, Neoplasm; Brefeldin A; Chloroquine; Cycloheximide; Epitopes, T-Lymphocyte; Female; Mice; Mice, Inbred BALB C; Microscopy, Confocal; T-Lymphocytes, Cytotoxic | 2002 |
Phosphoantigen presentation by macrophages to mycobacterium tuberculosis--reactive Vgamma9Vdelta2+ T cells: modulation by chloroquine.
Topics: Adult; Antigen Presentation; Antigen-Presenting Cells; Antigens, Bacterial; Brefeldin A; Cell Division; Chloroquine; Diphosphates; Humans; Interferon-gamma; Interleukin-2; Macrophages; Middle Aged; Mycobacterium tuberculosis; Phosphoproteins; Protein Synthesis Inhibitors; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes | 2002 |
Dendritic cell maturation enhances CD8+ T-cell responses to exogenous antigen via a proteasome-independent mechanism of major histocompatibility complex class I loading.
Topics: Animals; Antigen Presentation; Brefeldin A; CD4-Positive T-Lymphocytes; CD40 Antigens; CD8-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Chloroquine; Dendritic Cells; Dose-Response Relationship, Immunologic; Female; Histocompatibility Antigens Class I; ISCOMs; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Ovalbumin | 2003 |
Selective lack of the C16:0 fatty acid isoform of sulfatide in pancreas of type II diabetic animal models.
Topics: Animals; Brefeldin A; Chloroquine; Chromatography, Thin Layer; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Fumonisins; Galactosylceramides; Humans; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Obese; Microscopy, Electron; Protein Isoforms; Protein Synthesis Inhibitors; Rats; Rats, Inbred Lew; Spectrometry, Mass, Electrospray Ionization; Sulfoglycosphingolipids | 2003 |
pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes.
Topics: Amino Acid Sequence; Androstadienes; Animals; Biological Transport; Brefeldin A; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Cells, Cultured; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cycloheximide; Cytosol; Endosomes; Enzyme Inhibitors; Hepatocytes; Hydrogen-Ion Concentration; Liver Neoplasms; Metabolism; Molecular Sequence Data; Nocodazole; Protein Synthesis Inhibitors; Rats; Recombinant Proteins; Time Factors; Wortmannin | 2003 |
Cross-presentation of a CMV pp65 epitope by human dendritic cells using bee venom PLA2 as a membrane-binding vector.
Topics: Antigen Presentation; Antigens, Viral; Bee Venoms; Brefeldin A; CD8-Positive T-Lymphocytes; Cell Membrane; Chloroquine; Cross-Priming; Dendritic Cells; Endosomes; Histocompatibility Antigens Class I; Humans; Immunodominant Epitopes; Lymphocyte Activation; Phospholipases A; Phospholipases A2; Phosphoproteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Structure, Secondary; Recombinant Fusion Proteins; Viral Matrix Proteins | 2005 |
Intracellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins E; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Brefeldin A; Chloroquine; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Cyclodextrins; Female; Fluorescent Antibody Technique; Humans; Lipoproteins, VLDL; Microscopy, Confocal; Monensin; Protein Transport | 2006 |
Dendritic cells process antigens encapsulated in a biodegradable polymer, poly(D,L-lactide-co-glycolide), via an alternate class I MHC processing pathway.
Topics: Acetylcysteine; Antigen Presentation; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Brefeldin A; Cell Line; Chloroquine; Dendritic Cells; Histocompatibility Antigens Class I; Humans; Lactic Acid; Nanospheres; Ovalbumin; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2007 |
Simultaneous presentation and cross-presentation of immune-stimulating complex-associated cognate antigen by antigen-specific B cells.
Topics: Acetylcysteine; Adoptive Transfer; Animals; Antigen Presentation; Antigens; B-Lymphocytes; Brefeldin A; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Chloroquine; Cysteine Proteinase Inhibitors; Epitopes, B-Lymphocyte; ISCOMs; Kinetics; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Mice, Transgenic; Muramidase; Ovalbumin; Peptide Fragments; Receptors, Antigen, T-Cell; Vaccination | 2008 |
Rosette formation by macrophages with adhered T lymphocytes is precluded by inhibitors of antigen processing and presentation.
Topics: Adolescent; Adult; Antigen Presentation; Antirheumatic Agents; Brefeldin A; Cell Adhesion; Cells, Cultured; Chloroquine; Female; HLA-DR Antigens; Humans; Macrophages; Male; Middle Aged; Protein Synthesis Inhibitors; T-Lymphocytes | 2008 |
Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation.
Topics: Animals; Brefeldin A; Chickens; Chloroquine; Dendritic Cells; Endocytosis; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Liposomes; Macrophages; Mice; Mice, Inbred NOD; Muramidase | 2009 |
Investigation of the Plasmodium falciparum food vacuole through inducible expression of the chloroquine resistance transporter (PfCRT).
Topics: Animals; Base Sequence; Blotting, Western; Brefeldin A; Cell Compartmentation; Chloroquine; DNA Primers; Fluorescent Antibody Technique; Membrane Transport Proteins; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Vacuoles | 2012 |
The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling.
Topics: Antimalarials; Brefeldin A; Caveolin 1; Cell Membrane; Cell Movement; Cell Proliferation; Chloroquine; Endocytosis; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydrazones; Membrane Microdomains; Molecular Motor Proteins; Myosin Type I; Neovascularization, Physiologic; Protein Synthesis Inhibitors; Protein Transport; RNA, Messenger; Secretory Pathway; Signal Transduction; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Pharmacological agents with inherent anti-autophagic activity improve the cytotoxicity of imatinib.
Topics: Antineoplastic Agents; Autophagy; Benzamides; Brefeldin A; Cell Cycle Checkpoints; Cell Shape; Cell Survival; Chloroquine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Imatinib Mesylate; K562 Cells; Piperazines; Pyrimidines; Vincristine | 2013 |