chloroquine has been researched along with benzyloxycarbonylleucyl-leucyl-leucine aldehyde in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 8 (26.67) | 29.6817 |
| 2010's | 16 (53.33) | 24.3611 |
| 2020's | 3 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Androphy, EJ; Boaler, PJ; Burnett, BG; Calder, AN; Cherry, JJ; Choi, S; Cuny, GD; Fritsche, M; Glicksman, MA; Hodgetts, KJ; Kern, NL; Li, H; Lorson, CL; Lusic, H; Quist, KM; Rietz, A; Xing, X | 1 |
| Chen, F; Demers, LM; Kuhn, DC; Lu, Y; Maki, M; Shi, X; Sun, SC | 1 |
| Harney, J; Larsen, PR; Steinsapir, J | 1 |
| Friedmann, JM; Thévenod, F | 1 |
| Henry, P; Marchese, A; Morrione, A; Rotin, D; Vecchione, A | 1 |
| Baruch, A; Bogyo, M; Erickson, A; Goulet, B; Moon, NS; Nepveu, A; Poirier, M; Sansregret, LL | 1 |
| Benveniste, EN; Choi, C; Choi, K; Jeong, E; Kwon, D; Park, J | 1 |
| Caron, NJ; Quenneville, SP; Tremblay, JP | 1 |
| Jarosz-Wilkołazka, A; Staszczak, M | 1 |
| Fried, SK; Lee, MJ | 1 |
| Lim, G; Mao, J; Sung, B; Wang, S; Yang, L | 1 |
| Jia, L; Wang, MM; Yu, G; Zhang, Y | 1 |
| Kubo, M; Obata, F; Ohta, E | 1 |
| Henderson, P; Hupp, T; Lin, Y; Pettersson, S; Satsangi, J; Stevens, C | 1 |
| Closs, EI; Förstermann, U; Habermeier, A; Jaenecke, I; Karbach, S; Martiné, U; Simon, A; Slenzka, A | 1 |
| Anastas, JN; Aoyagi, A; Berndt, JD; Moon, RT; Tang, L; Yang, P | 1 |
| Yang, H; Zhou, L | 1 |
| Ann, EJ; Kim, MY; Kim, SM; Mo, JS; Park, HS; Yoon, JH | 1 |
| Burgis, NE; Lewis, BS; Sipes, RK; Xia, X | 1 |
| Ding, ZB; Fan, J; Gu, CY; Hui, B; Liu, WR; Peng, YF; Shi, GM; Shi, YH; Yang, H; Zhou, J | 1 |
| Beraldi, E; Fazli, L; Furukawa, J; Gleave, ME; Kumano, M; Shiota, M; Wiedmann, RM; Zardan, A; Zhang, F; Zoubeidi, A | 1 |
| Aminake, MN; Brouwer, AJ; Joanny, F; Jonker, AM; Knittel, S; Liskamp, RM; Mordmüller, B; Pradel, G; Tschan, S; Wagner, L; Werkhoven, PR | 1 |
| Chababi, W; Donates, YC; Gui, Y; Ilangumaran, S; Mayhue, M; Ramanathan, S; Saucier, C; Tobelaim, WS; Yeganeh, M; Yoshimura, A | 1 |
| Caldarola, S; Catalano, M; Cecconi, F; Corazzari, M; D'Alessandro, G; Di Bartolomeo, S; Esposito, V; Faienza, F; Lepore, F; Limatola, C; Valacca, C | 1 |
| Brilot, F; Fonteneau, JF; Gannagé, M; Münz, C | 1 |
| Chen, G; Fan, W; Lai, Y; Long, Y; Wang, X; Zhu, B | 1 |
| Ding, Y; He, Y; Liu, R; Mei, YA; Yang, G; Zhou, MH | 1 |
| Fenton, RA; Karaduman, T; Mergen, H; Moeller, HB; Saglar Ozer, E | 1 |
| Edemir, B; Kaiser, M | 1 |
| Chan, WK; Chen, J; Russu, WA; Yang, Y | 1 |
30 other study(ies) available for chloroquine and benzyloxycarbonylleucyl-leucyl-leucine aldehyde
| Article | Year |
|---|---|
Discovery of a Small Molecule Probe That Post-Translationally Stabilizes the Survival Motor Neuron Protein for the Treatment of Spinal Muscular Atrophy.
Topics: Anilides; Area Under Curve; Benzamides; Cell Line; Drug Discovery; Half-Life; Humans; Isoxazoles; Molecular Probes; Muscular Atrophy, Spinal; Protein Processing, Post-Translational; Protein Stability; Quinolones; Structure-Activity Relationship; Survival of Motor Neuron 1 Protein; Thiazoles | 2017 |
Calpain contributes to silica-induced I kappa B-alpha degradation and nuclear factor-kappa B activation.
Topics: Animals; Blotting, Western; Calcium-Binding Proteins; Calpain; Cell Extracts; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; DNA, Complementary; I-kappa B Proteins; Leupeptins; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Silicon Dioxide; Transfection | 1997 |
Type 2 iodothyronine deiodinase in rat pituitary tumor cells is inactivated in proteasomes.
Topics: Adenosine Triphosphate; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chloroquine; Cycloheximide; Cysteine Endopeptidases; Cytochalasin B; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Isoenzymes; Leupeptins; Multienzyme Complexes; Neoplasm Proteins; Pituitary Neoplasms; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Rats; Thyroxine; Triiodothyronine, Reverse; Tumor Cells, Cultured; Ubiquitins | 1998 |
Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K(+)-ATPase through proteasomal and endo-/lysosomal proteolytic pathways.
Topics: Ammonium Chloride; Animals; Biological Transport; Cadmium; Cell Line; Cell Membrane; Chloroquine; Cysteine Endopeptidases; Endosomes; Enzyme Stability; Kidney Tubules, Proximal; Leupeptins; Lysosomes; Models, Biological; Multienzyme Complexes; Oxidative Stress; Proteasome Endopeptidase Complex; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Serine Proteinase Inhibitors; Sodium-Potassium-Exchanging ATPase; Ubiquitins | 1999 |
The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor.
Topics: Animals; Calcium-Binding Proteins; Cell Membrane; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endosomal Sorting Complexes Required for Transport; Fibroblasts; Gene Expression; GRB10 Adaptor Protein; Insulin-Like Growth Factor I; Leupeptins; Ligands; Ligases; Lysosomes; Macromolecular Substances; Mice; Multienzyme Complexes; Mutation; Nedd4 Ubiquitin Protein Ligases; Precipitin Tests; Proteasome Endopeptidase Complex; Proteins; Receptor, IGF Type 1; Recombinant Proteins; src Homology Domains; Transport Vesicles; Ubiquitin; Ubiquitin-Protein Ligases | 2003 |
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor.
Topics: Animals; Catalysis; Cathepsin L; Cathepsins; Cell Cycle; Cell Extracts; Cell Nucleus; Chloroquine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Homeodomain Proteins; Leupeptins; Mice; NIH 3T3 Cells; Nuclear Proteins; Protein Isoforms; Protein Processing, Post-Translational; Protein Sorting Signals; Recombinant Proteins; Repressor Proteins; RNA, Messenger; S Phase; Subcellular Fractions | 2004 |
Reactive oxygen species mediate chloroquine-induced expression of chemokines by human astroglial cells.
Topics: Acetylcysteine; Astrocytes; Biphenyl Compounds; Cells, Cultured; Chemokines; Chloroquine; Dose-Response Relationship, Drug; Encephalitis; Humans; Inflammation Mediators; Leupeptins; NF-kappa B; Onium Compounds; Reaction Time; Reactive Oxygen Species; RNA, Messenger; Tosylphenylalanyl Chloromethyl Ketone | 2004 |
Endosome disruption enhances the functional nuclear delivery of Tat-fusion proteins.
Topics: Animals; Cell Nucleus; Chloroquine; Cytosol; Dose-Response Relationship, Drug; Endocytosis; Endosomes; Enzyme Inhibitors; Gene Products, tat; Gene Transfer Techniques; Immunoblotting; Integrases; Kinetics; Leupeptins; Lysosomes; Macrolides; Mice; NIH 3T3 Cells; Recombinant Fusion Proteins; Sucrose; Temperature; Time Factors; Viral Proteins | 2004 |
Inhibition of the proteasome strongly affects cadmium stimulated laccase activity in Trametes versicolor.
Topics: Acetylcysteine; Cadmium; Chloroquine; Dose-Response Relationship, Drug; Fungal Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Laccase; Leupeptins; Mycelium; Proteasome Endopeptidase Complex; Proteasome Inhibitors | 2005 |
Multilevel regulation of leptin storage, turnover, and secretion by feeding and insulin in rat adipose tissue.
Topics: Adipocytes; Adipose Tissue; Animals; Blotting, Northern; Body Weight; Chloroquine; Cycloheximide; Insulin; Iodine Isotopes; Leptin; Leupeptins; Lysosomes; Male; Rats; Rats, Wistar; RNA, Messenger; Starvation; Sulfur Isotopes | 2006 |
Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation.
Topics: Acetylcysteine; Amino Acid Transport System X-AG; Analgesics, Opioid; Animals; Chloroquine; Excitatory Amino Acid Transporter 3; Humans; Leupeptins; Male; Morphine; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Ubiquitin | 2008 |
Lysosome-dependent degradation of Notch3.
Topics: Ammonium Chloride; Animals; Chloroquine; Cysteine Proteinase Inhibitors; Epithelial Cells; HeLa Cells; Humans; Leupeptins; Lysosomes; Mice; Protein Transport; Receptor, Notch3; Receptors, Notch; Signal Transduction; Transfection | 2009 |
Prevention of intracellular degradation of I2020T mutant LRRK2 restores its protectivity against apoptosis.
Topics: Acetylcysteine; Apoptosis; Chloroquine; Gene Knockdown Techniques; Humans; Hydrogen Peroxide; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Leupeptins; Lysosomes; Parkinson Disease; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Serine-Threonine Kinases | 2010 |
Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; Autophagy; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Line; Cell Line, Tumor; Chloroquine; Death-Associated Protein Kinases; Fibroblasts; Gene Expression; HEK293 Cells; Humans; Leupeptins; Lysosomes; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred Strains; Mice, Knockout; Models, Biological; Monomeric GTP-Binding Proteins; Multiprotein Complexes; Mutation, Missense; Neuropeptides; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Interaction Domains and Motifs; Proteins; Ras Homolog Enriched in Brain Protein; Regulatory-Associated Protein of mTOR; Ribosomal Protein S6 Kinases; RNA, Small Interfering; Sequence Deletion; Sirolimus; TOR Serine-Threonine Kinases; Transfection; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2011 |
Relative contribution of different l-arginine sources to the substrate supply of endothelial nitric oxide synthase.
Topics: Arginine; Atherosclerosis; Biological Transport; Cell Line; Chloroquine; Chromatography, High Pressure Liquid; Citrulline; Dipeptides; Endothelium, Vascular; Genes, Reporter; Histidine; Human Umbilical Vein Endothelial Cells; Humans; Leupeptins; Lysosomes; Membrane Transport Proteins; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteolysis | 2011 |
Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.
Topics: Amyloid Precursor Protein Secretases; Animal Structures; Animals; beta Catenin; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Line, Tumor; Cell Membrane; Chloroquine; DNA-Binding Proteins; Endosomal Sorting Complexes Required for Transport; Female; Gene Expression; HEK293 Cells; HeLa Cells; Humans; Intracellular Membranes; Leupeptins; Low Density Lipoprotein Receptor-Related Protein-6; Lysosomes; Mice; Mutation; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Interaction Domains and Motifs; Protein Interaction Mapping; Protein Transport; rab5 GTP-Binding Proteins; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering; Signal Transduction; Transcription Factors; Transfection; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination; Wnt Proteins; Wnt Signaling Pathway; Wnt3A Protein | 2011 |
The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.
Topics: Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Carcinoma, Renal Cell; Cell Line, Tumor; Chloroquine; Cysteine Proteinase Inhibitors; Down-Regulation; Enzyme Activation; ErbB Receptors; Humans; Kidney Neoplasms; Leupeptins; Proto-Oncogene Proteins c-cbl; RNA Interference; Ubiquitination; Von Hippel-Lindau Tumor Suppressor Protein | 2011 |
Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase.
Topics: Acetylcysteine; Ammonium Chloride; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Gene Knockout Techniques; HEK293 Cells; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Leupeptins; Lysosomes; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Presenilin-1; Presenilin-2; Proteasome Inhibitors; Proteolysis; Receptor, Notch1; Transcription, Genetic; Transcriptional Activation; Ubiquitination | 2012 |
Evidence that aberrant protein metabolism contributes to chemoresistance in multiple myeloma cells.
Topics: Antineoplastic Agents; B-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Chloroquine; Drug Resistance, Neoplasm; Humans; Leupeptins; Lysosomes; Male; Melphalan; Multiple Myeloma; Neoplasm Proteins; Proteasome Endopeptidase Complex; Proteins; Proteolysis | 2012 |
Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.
Topics: Adenine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Boronic Acids; Bortezomib; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chloroquine; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Membrane Proteins; Microtubule-Associated Proteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines | 2012 |
Cotargeting stress-activated Hsp27 and autophagy as a combinatorial strategy to amplify endoplasmic reticular stress in prostate cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Chloroquine; Drug Synergism; Endoplasmic Reticulum Stress; Gene Expression; Gene Silencing; HSP27 Heat-Shock Proteins; Humans; Leupeptins; Male; Oligonucleotides, Antisense; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Tumor Burden; Ubiquitin; Xenograft Model Antitumor Assays | 2012 |
Broad-spectrum antimalarial activity of peptido sulfonyl fluorides, a new class of proteasome inhibitors.
Topics: Animals; Antimalarials; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Female; HEK293 Cells; HeLa Cells; Humans; Leupeptins; Mice; Oligopeptides; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Schizonts; Sulfinic Acids | 2013 |
Regulation of MET receptor tyrosine kinase signaling by suppressor of cytokine signaling 1 in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; Chloroquine; COS Cells; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hep G2 Cells; Humans; Leupeptins; Liver Neoplasms; Mice; Proto-Oncogene Proteins c-cbl; Proto-Oncogene Proteins c-met; Signal Transduction; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins | 2015 |
Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells.
Topics: Animals; Autophagy; Cell Line, Tumor; Cell Movement; Chloroquine; Culture Media, Serum-Free; Epithelial-Mesenchymal Transition; Glioblastoma; Humans; Leupeptins; Mice; Naphthyridines; Neoplasm Invasiveness; Up-Regulation | 2015 |
The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer.
Topics: Acetylcysteine; Antigen Presentation; Antigens, Neoplasm; Autophagy; Autophagy-Related Protein 12; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Chloroquine; Dendritic Cells; Endocytosis; Epitopes, T-Lymphocyte; Histocompatibility Antigens Class II; Humans; Immunotherapy, Adoptive; Leupeptins; Lymphocyte Activation; Lysosomal-Associated Membrane Protein 2; Melanoma; Membrane Proteins; RNA Interference; RNA, Small Interfering; Small Ubiquitin-Related Modifier Proteins | 2016 |
NPAS4 Facilitates the Autophagic Clearance of Endogenous Tau in Rat Cortical Neurons.
Topics: Adenine; Animals; Autophagy; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Cerebral Cortex; Chloroquine; Cyclin-Dependent Kinase 5; Glycogen Synthase Kinase 3; Leupeptins; Neurons; Proteolysis; Rats; Rats, Sprague-Dawley; tau Proteins | 2016 |
Flotillin-1 downregulates K(+) current by directly coupling with Kv2.1 subunit.
Topics: Chloroquine; Down-Regulation; Gene Expression; HEK293 Cells; Humans; Leupeptins; Membrane Proteins; Microscopy, Fluorescence; Protein Binding; Protein Subunits; RNA Interference; RNA, Small Interfering; Shab Potassium Channels | 2016 |
Molecular characterization of an aquaporin-2 mutation causing a severe form of nephrogenic diabetes insipidus.
Topics: Animals; Aquaporin 2; Cell Line; Cell Membrane Permeability; Chloroquine; Diabetes Insipidus, Nephrogenic; Dogs; HEK293 Cells; Humans; Kidney Tubules, Collecting; Leupeptins; Madin Darby Canine Kidney Cells; Oocytes; Protein Folding; Proteostasis Deficiencies; Ubiquitination; Xenopus laevis | 2020 |
Lithium Chloride and GSK3 Inhibition Reduce Aquaporin-2 Expression in Primary Cultured Inner Medullary Collecting Duct Cells Due to Independent Mechanisms.
Topics: Animals; Aquaporin 2; Aquaporin 3; Aquaporin 4; Cells, Cultured; Chloroquine; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Female; Glycogen Synthase Kinase 3; Indoles; Kidney Tubules, Collecting; Leupeptins; Lithium Chloride; Macrolides; Maleimides; Protein Kinase Inhibitors; Proteolysis; Pyrimidines; Pyrroles; Rats, Wistar; RNA, Messenger | 2020 |
The Aryl Hydrocarbon Receptor Undergoes Chaperone-Mediated Autophagy in Triple-Negative Breast Cancer Cells.
Topics: Amino Acid Sequence; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Chaperone-Mediated Autophagy; Chloroquine; Cytochrome P-450 CYP1A1; Estrogen Receptor alpha; Humans; Leupeptins; Lysosomal-Associated Membrane Protein 2; Lysosomes; MCF-7 Cells; Proteolysis; Receptors, Aryl Hydrocarbon; Receptors, Progesterone; RNA Interference; Signal Transduction; Triple Negative Breast Neoplasms | 2021 |