chloroquine has been researched along with bafilomycin a in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 11 (35.48) | 24.3611 |
| 2020's | 4 (12.90) | 2.80 |
| Authors | Studies |
|---|---|
| Aerts, H; Renkema, H; Schurr, E; van Es, HH | 1 |
| Haynes, DR; Howie, DW; Pearcy, MJ; Rogers, SD; Vernon-Roberts, B | 1 |
| Inoue, K; Kurosumi, K; Nakayama, K; Tanaka, S; Yora, T | 1 |
| Boyer, JL; Hayes, JH; Rios-Velez, L; Soroka, CJ | 1 |
| Almonte, C; Brisson, M; Huang, L; Tseng, WC; Watkins, S | 1 |
| Griffin, GE; Harrison, TS; Levitz, SM | 1 |
| Levitz, SM; Weber, SM | 1 |
| Chang, JE; Dannies, PS; Lee, MS; Zhu, YL | 1 |
| Adám, E; Banizs, B; Dobay, O; Glatz, K; Huszár, T; Jeney, C; Nász, I | 1 |
| Benveniste, EN; Choi, C; Kwon, D; Oh, JW; Park, J | 1 |
| Balbis, A; Baquiran, G; Dumas, V; Posner, BI | 1 |
| Gorelick, FS; Kolodecik, TR; Thrower, EC; Waterford, SD | 1 |
| Bates, EE; Benguigui, B; Caux, C; de Bouteiller, O; Hasan, UA; Hubac, S; Merck, E; Trinchieri, G | 1 |
| Lee, CM; Tannock, IF | 1 |
| Habuchi, O; Kimata, K; Kondo, S; Matsumura, K; Morisaki, T; Ohtake, S | 1 |
| Chauhan, A; Nath, A; Vijaykumar, TS | 1 |
| Birkus, G; Chou, T; Cihlar, T; Frey, CR; Kutty, N; McDermott, M; Shribata, R; Wagner, C | 1 |
| Kandala, PK; Srivastava, SK | 1 |
| Liu, CX; Ma, CM; Sun, Y; Wei, W; Wu, YL; Yan, H; Zhao, S | 1 |
| De Robertis, EM; Dobrowolski, R; Gumper, I; Ploper, D; Sabatini, DD; Snitkin, H; Vick, P | 1 |
| Bellosillo, B; Bigas, A; Colomer, C; Espinosa, L; Iglesias, M; Margalef, P; Martínez-Iniesta, M; Montagut, C; Salazar, R; Villanueva, A | 1 |
| Adam, V; Cerna, T; Doktorova, H; Eckschlager, T; Frei, E; Groh, T; Hrabeta, J; Khalil, MA; Kizek, R; Poljakova, J; Stiborova, M; Uhlik, J | 1 |
| Fagerlund, R; Fortmann, KT; Hoffmann, A; Lewis, RD; Ngo, KA | 1 |
| Brigger, D; Garattini, E; Schläfli, AM; Tschan, MP | 1 |
| Astolfi, M; Buschmann, MD; Lavertu, M; Thibault, M | 1 |
| Akpinar, B; Debnath, S; Laukova, J; Olsson, M; Safarikova, B; Vaculova, AH; Zhivotovsky, B | 1 |
| Adame, A; Barkovits, K; Bergmann, A; Buzás, EI; Emmanouilidou, E; Galasko, D; Kittel, A; Klucken, J; Lie, DC; Marcus, K; Marxreiter, F; Masliah, E; Menges, S; Minakaki, G; Mollenhauer, B; Rockenstein, E; Schaeffner, I; Schlötzer-Schrehardt, U; Vekrellis, K; Winkler, J; Xiang, W | 1 |
| Edemir, B; Kaiser, M | 1 |
| Chiu, CH; Hsu, HJ; Hsu, MC; Huang, C; Jiang, YF; Jong, DS; Wang, ME; Wu, LS | 1 |
| Rein, T | 1 |
| Dutta, RK; Kwon, HM; Maharjan, Y; Park, C; Park, R; Son, J; Wei, X | 1 |
1 review(s) available for chloroquine and bafilomycin a
| Article | Year |
|---|---|
Harnessing autophagy to fight SARS-CoV-2: An update in view of recent drug development efforts.
Topics: Antidepressive Agents; Antiviral Agents; Artesunate; Autophagy; Chloroquine; COVID-19 Drug Treatment; Drug Development; Drug Repositioning; Endoplasmic Reticulum; Endosomes; Humans; Hydroxychloroquine; Imatinib Mesylate; Infliximab; Intracellular Membranes; Ivermectin; Macrolides; Middle East Respiratory Syndrome Coronavirus; Niclosamide; Pandemics; RNA, Viral; SARS-CoV-2; Virus Replication | 2022 |
30 other study(ies) available for chloroquine and bafilomycin a
| Article | Year |
|---|---|
Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr1 gene.
Topics: Acids; Ammonium Chloride; Animals; Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Cells, Cultured; Chloroquine; CHO Cells; Cricetinae; Gene Expression; Hydrogen-Ion Concentration; Lysosomes; Macrolides; Plasmodium falciparum; Proton-Translocating ATPases; Protozoan Proteins; Stereoisomerism; Transfection | 1994 |
Drug inhibition of the macrophage response to metal wear particles in vitro.
Topics: Ammonium Chloride; Animals; Anti-Bacterial Agents; Cells, Cultured; Chloroquine; Chromium Compounds; Corrosion; Cytochalasin B; Dinoprostone; Hydrogen-Ion Concentration; Interleukin-6; Macrolides; Macrophages; Phagocytosis; Piroxicam; Rats; Titanium | 1996 |
Proteolytic processing of pro-opiomelanocortin occurs in acidifying secretory granules of AtT-20 cells.
Topics: Animals; Anti-Bacterial Agents; Aspartic Acid Endopeptidases; Chloroquine; Cytoplasmic Granules; Endopeptidases; Enzyme Inhibitors; Macrolides; Mice; Organelles; Peptide Fragments; Pro-Opiomelanocortin; Proprotein Convertase 1; Proprotein Convertases; Protein Processing, Post-Translational; Proton-Translocating ATPases; Tumor Cells, Cultured; Vacuolar Proton-Translocating ATPases | 1997 |
Hepatic sequestration and modulation of the canalicular transport of the organic cation, daunorubicin, in the Rat.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Bile Canaliculi; Biological Transport; Bucladesine; Cations; Chloroquine; Daunorubicin; Kinetics; Liver; Macrolides; Male; Mitochondrial Proteins; Nocodazole; Rats; Rats, Wistar; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Taurocholic Acid; Verapamil | 1999 |
Subcellular trafficking of the cytoplasmic expression system.
Topics: Anti-Bacterial Agents; Cation Exchange Resins; Cell Line; Cell Nucleus; Chloroquine; Cytochalasin B; Cytoplasm; DNA; Endocytosis; Enzyme Inhibitors; Epidermal Growth Factor; Fatty Acids, Monounsaturated; Gene Expression Regulation; Humans; Kidney; Lipids; Liposomes; Luciferases; Macrolides; Mitosis; Nocodazole; Promoter Regions, Genetic; Protamines; Quaternary Ammonium Compounds; Subcellular Fractions | 1999 |
Conditional lethality of the diprotic weak bases chloroquine and quinacrine against Cryptococcus neoformans.
Topics: Anti-Bacterial Agents; Antifungal Agents; Cell Division; Chloroquine; Cryptococcus neoformans; Drug Combinations; Enzyme Inhibitors; Macrolides; Microbial Sensitivity Tests; Quinacrine | 2000 |
Chloroquine interferes with lipopolysaccharide-induced TNF-alpha gene expression by a nonlysosomotropic mechanism.
Topics: Anti-Bacterial Agents; Biological Transport; Cell Nucleus; Chemokine CCL5; Chloroquine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Immunosuppressive Agents; Interleukin-1; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Lysosomes; Macrolides; NF-kappa B; NF-kappa B p50 Subunit; Protein Biosynthesis; Protein Processing, Post-Translational; RNA, Messenger; Transcription Factor RelA; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2000 |
Acquisition of Lubrol insolubility, a common step for growth hormone and prolactin in the secretory pathway of neuroendocrine cells.
Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Chloroquine; COS Cells; Dinitrobenzenes; Endoplasmic Reticulum; Epidermal Growth Factor; Estradiol; Human Growth Hormone; Hydrogen-Ion Concentration; Insulin; Macrolides; Mutation; Pituitary Gland; Polyethylene Glycols; Prolactin; Protein Transport; Rats; Secretory Vesicles; Solubility; Substrate Specificity; Tumor Cells, Cultured; Ultracentrifugation | 2001 |
The endosomal epsilon-coatomer protein is involved in human adenovirus type 5 internalisation.
Topics: Adenoviruses, Human; Animals; Anti-Bacterial Agents; Chloroquine; CHO Cells; Coatomer Protein; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Cricetinae; Endocytosis; Endosomes; HeLa Cells; Humans; Hydrogen-Ion Concentration; Macrolides; Proton Pump Inhibitors; Proton Pumps; Receptors, Virus; Virus Replication | 2002 |
Chloroquine induces activation of nuclear factor-kappaB and subsequent expression of pro-inflammatory cytokines by human astroglial cells.
Topics: Ammonium Chloride; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Astrocytes; Cells, Cultured; Chloroquine; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inflammation; Interleukin-1; Interleukin-6; Lipopolysaccharides; Lymphotoxin-alpha; Lymphotoxin-beta; Macrolides; Membrane Proteins; Mice; Microglia; Monocytes; NF-kappa B; Tumor Necrosis Factor-alpha | 2003 |
Effect of inhibiting vacuolar acidification on insulin signaling in hepatocytes.
Topics: Animals; Antioxidants; Binding Sites; Cell Division; Cell Membrane; Cells, Cultured; Chloroquine; Endosomes; Enzyme Inhibitors; Evolution, Molecular; Glycogen; Hepatocytes; Histidine; Insulin; Macrolides; Male; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Phylogeny; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Superoxides; Swine; Thymidine; Time Factors; Tyrosine | 2004 |
Vacuolar ATPase regulates zymogen activation in pancreatic acini.
Topics: Amylases; Animals; Calcium; Carbachol; Cell Membrane; Cells, Cultured; Ceruletide; Chloroquine; Chymotrypsin; Enzyme Activation; Enzyme Precursors; Hydrogen-Ion Concentration; Macrolides; Male; Monensin; Pancreas; Protein Subunits; Protein Transport; Rats; Rats, Sprague-Dawley; Solubility; Thapsigargin; Trypsin; Vacuolar Proton-Translocating ATPases | 2005 |
Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH.
Topics: Amino Acid Sequence; Antigens, CD; Antirheumatic Agents; Base Sequence; Binding Sites; Blotting, Western; Calcium; Cell Line; Cell Membrane; Cell Separation; Chloroquine; Cross-Linking Reagents; Cysteine; Cytokines; Dendritic Cells; Dimerization; DNA; Dose-Response Relationship, Drug; Endosomes; Enzyme Inhibitors; Flow Cytometry; Genes, Dominant; Genes, Reporter; Glycosylation; Humans; Hydrogen-Ion Concentration; Leucine; Leukocytes, Mononuclear; Ligands; Luciferases; Lysosomes; Macrolides; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NF-kappa B; Phagosomes; Protein Binding; Protein Structure, Tertiary; Receptors, IgG; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Signal Transduction; Time Factors; Toll-Like Receptor 3; Transfection; Tyrosine; U937 Cells | 2005 |
Inhibition of endosomal sequestration of basic anticancer drugs: influence on cytotoxicity and tissue penetration.
Topics: Animals; Antibiotics, Antineoplastic; Antimalarials; Antineoplastic Agents; Breast Neoplasms; Chloroquine; Doxorubicin; Drug Interactions; Endosomes; Enzyme Inhibitors; Hydrogen-Ion Concentration; Macrolides; Mammary Neoplasms, Animal; Mice; Mitoxantrone; Omeprazole; Sarcoma; Tumor Cells, Cultured | 2006 |
Expression of sulfotransferases involved in the biosynthesis of chondroitin sulfate E in the bone marrow derived mast cells.
Topics: Ammonium Chloride; Animals; Bone Marrow Cells; Cells, Cultured; Chloroquine; Chondroitin Sulfates; Chromatography, Gel; Chromatography, High Pressure Liquid; Disaccharides; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hydrogen-Ion Concentration; Macrolides; Mast Cells; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulfotransferases | 2008 |
Chloroquine mediated molecular tuning of astrocytes for enhanced permissiveness to HIV infection.
Topics: Antirheumatic Agents; Astrocytes; Brain; Cells, Cultured; Chloroquine; Enzyme Inhibitors; HIV; HIV Infections; Humans; Jurkat Cells; Macrolides | 2008 |
Role of cathepsin A and lysosomes in the intracellular activation of novel antipapillomavirus agent GS-9191.
Topics: Antiviral Agents; Cathepsin A; Cell Line, Tumor; Chloroquine; Female; HeLa Cells; Humans; Hydrogen-Ion Concentration; Immunoblotting; Lysosomes; Macrolides; Papillomaviridae; Phenylalanine; Uterine Cervical Neoplasms | 2011 |
Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling glucose regulatory protein 78 and AMPK.
Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinase Kinases; Autophagy; Autophagy-Related Protein 12; Calcium Signaling; Carcinoma; Cell Line, Tumor; Chloroquine; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endoribonucleases; Female; Heat-Shock Proteins; Humans; Indoles; Macrolides; Membrane Proteins; Microtubule-Associated Proteins; Ovarian Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Sequestosome-1 Protein; Small Ubiquitin-Related Modifier Proteins; Transcription Factor CHOP | 2012 |
Autophagy inhibition enhances isobavachalcone-induced cell death in multiple myeloma cells.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cells, Cultured; Chalcones; Chloroquine; Gene Knockdown Techniques; HEK293 Cells; Humans; Macrolides; Membrane Potential, Mitochondrial; Membrane Proteins; Mitochondria; Multiple Myeloma; Protein Kinase C-delta; Proteolysis | 2012 |
Presenilin deficiency or lysosomal inhibition enhances Wnt signaling through relocalization of GSK3 to the late-endosomal compartment.
Topics: 3T3 Cells; Animals; Antimalarials; beta Catenin; Cell Line; Chloroquine; Endosomal Sorting Complexes Required for Transport; Glycogen Synthase Kinase 3; HEK293 Cells; HeLa Cells; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Lysosomes; Macrolides; Mice; Multivesicular Bodies; Presenilins; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; tau Proteins; Tetraspanin 30; Wnt Proteins | 2012 |
BRAF-induced tumorigenesis is IKKα-dependent but NF-κB-independent.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Chloroquine; DNA; Dose-Response Relationship, Drug; Endosomes; HEK293 Cells; Humans; I-kappa B Kinase; Inflammation; Macrolides; Mice; Mice, Knockout; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; NF-kappa B p50 Subunit; NIH 3T3 Cells; Phosphorylation; Prognosis; Proto-Oncogene Proteins B-raf | 2015 |
Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chloroquine; DNA Adducts; Drug Resistance, Neoplasm; Ellipticines; Humans; Macrolides; Neuroblastoma; Vacuolar Proton-Translocating ATPases; Vacuoles | 2015 |
A Regulated, Ubiquitin-Independent Degron in IκBα.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Ankyrin Repeat; Cell Line; Chloroquine; Cycloheximide; DNA-Binding Proteins; Green Fluorescent Proteins; HEK293 Cells; Humans; I-kappa B Proteins; Lysosomes; Macrolides; Mice; NF-KappaB Inhibitor alpha; Proteolysis; Signal Transduction; Transcription Factor RelA; Ubiquitin | 2015 |
Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Cell Differentiation; Cell Line, Tumor; Chloroquine; Drug Resistance, Neoplasm; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Macrolides; Mammary Glands, Human; Microtubule-Associated Proteins; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; RNA, Small Interfering; Signal Transduction; Tretinoin; Ubiquitin-Activating Enzymes | 2015 |
Structure Dependence of Lysosomal Transit of Chitosan-Based Polyplexes for Gene Delivery.
Topics: Cell Survival; Chitosan; Chloroquine; DNA; Gene Transfer Techniques; HEK293 Cells; Humans; Lysosomes; Macrolides; Materials Testing; Transfection | 2016 |
Aberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activation.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Cell Membrane; Chloroquine; Cholesterol; Fluorouracil; HCT116 Cells; Humans; Ligands; Lysosomes; Macrolides; Mitochondria; Phagosomes; Protein Transport; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA Interference; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53 | 2016 |
Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype.
Topics: alpha-Synuclein; Animals; Autophagosomes; Autophagy; Biomarkers; Cells, Cultured; Chloroquine; Exosomes; Humans; Lewy Body Disease; Lysosomes; Macrolides; Mice; Neurons; Parkinson Disease; Protein Transport; Rats, Sprague-Dawley | 2018 |
Lithium Chloride and GSK3 Inhibition Reduce Aquaporin-2 Expression in Primary Cultured Inner Medullary Collecting Duct Cells Due to Independent Mechanisms.
Topics: Animals; Aquaporin 2; Aquaporin 3; Aquaporin 4; Cells, Cultured; Chloroquine; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Female; Glycogen Synthase Kinase 3; Indoles; Kidney Tubules, Collecting; Leupeptins; Lithium Chloride; Macrolides; Maleimides; Protein Kinase Inhibitors; Proteolysis; Pyrimidines; Pyrroles; Rats, Wistar; RNA, Messenger | 2020 |
Fatty acids suppress the steroidogenesis of the MA-10 mouse Leydig cell line by downregulating CYP11A1 and inhibiting late-stage autophagy.
Topics: Animals; Autophagy; Chloroquine; Cholesterol Side-Chain Cleavage Enzyme; Endocrine Cells; Fatty Acids; Gene Expression Regulation; Humans; Leydig Cells; Lipids; Macrolides; Male; Mice; Obesity; Sirolimus; Steroids | 2021 |
Intracellular cholesterol transport inhibition Impairs autophagy flux by decreasing autophagosome-lysosome fusion.
Topics: Autophagosomes; Autophagy; Chloroquine; Cholesterol; Lysosomes | 2022 |