chloroquine has been researched along with artesunic acid in 154 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.60) | 18.7374 |
| 1990's | 12 (7.79) | 18.2507 |
| 2000's | 61 (39.61) | 29.6817 |
| 2010's | 65 (42.21) | 24.3611 |
| 2020's | 12 (7.79) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, DQ; Dong, Y; He, H; Liu, DQ; Liu, RJ; Yang, HL; Yang, PF; Zhang, CY | 1 |
| Bunyaratvej, A; Butthep, P; Fucharoen, S; Yuthavong, Y | 1 |
| Huang, WJ; Li, J | 1 |
| Du, YL; Jiang, Q; Li, CS | 1 |
| Li, GD | 1 |
| Dong, Y; Liu, D; Liu, R; Yang, H; Yang, P; Zhang, B; Zhang, C | 1 |
| Alin, MH; Ashton, M; Bjorkman, A; Bwijo, BA; Kihamia, CM; Mtey, GJ; Premji, Z | 1 |
| Adams, PA; Berman, PA; Egan, TJ; Marsh, PJ; Silver, J | 1 |
| Ezedinachi, E | 1 |
| Davis, TM; Johnston, WA; Manning, LS; Skinner, TS | 1 |
| Heppner, DG; Kawamoto, F; Nguyen, TD; Sookto, P; Trieu, NT; Wimonwattrawatee, T; Wongsrichanalai, C | 1 |
| Dong, Y; Huang, KG; Liao, MZ; Liu, DQ; Yang, HL; Yang, PF; Yang, YM; Zhang, CY | 1 |
| Chang, HL; Chang, SC; Chen, YC; Fang, CT; Hsieh, WC; Hsueh, PR; Hung, CC | 1 |
| Ding, DB; Li, GF; Shi, YL; Yang, JD; Zhao, JH | 1 |
| Agbenyega, T; Agranoff, D; Appiah, JA; Bedu-Addo, G; Krishna, S; Mansor, SM; Navaratnam, V; Owusu-Ofori, AK; Planche, T; Ramanathan, S; Woodrow, C | 1 |
| Bloland, PB; Ettling, M; Meek, S | 1 |
| Coleman, R; Doherty, T; Jawara, M; Targett, G; von Seidlein, L; Walraven, G | 1 |
| Coleman, R; Deen, J; Doherty, T; Drakeley, C; Jawara, M; Milligan, P; Pinder, M; Sutherland, C; Targett, G; von Seidlein, L; Walraven, G | 1 |
| Adabayeri, V; Akanmori, BD; Asare-Odei, G; Goka, BQ; Kurtzhals, J; Neequaye, J; Ofori-Adjei, D; Ofori-Adjei, E; Quarshie, B | 1 |
| Ishiyama, A; Kohana, A; Manabe, C; Omura, S; Otoguro, K; Shiomi, K; Ui, H; Yamada, H | 1 |
| Fan, B; Huang, Z; Ma, X; Wen, Y; Yang, J; Yang, Z; Zhao, W | 1 |
| Belsare, H; Patel, AB | 1 |
| Anstey, NM; Baker, J; Cheng, Q; Suprianto, S; Tjitra, E | 1 |
| Folb, P; Gumede, B; Ryffel, B | 1 |
| Gao, B; Huang, K; Yang, H | 1 |
| Faiz, MA; Hossain, MA; Miller, RS; Noedl, H; Pang, LW; Rahman, MR; Samad, R; Wongsrichanalai, C; Yunus, EB | 1 |
| Coleman, R; Drakeley, CJ; Jawara, M; Milligan, P; Obisike, U; Pinder, M; Sutherland, CJ; Targett, GA; Walraven, G | 1 |
| Cox-Singh, J; Davis, TM; Doan, HN; Hewitt, S; Le, DC; Nguyen, MH; Nguyen, TH; Tran, BK; Tran, QT; Vo, NP | 1 |
| Feng, XP; Liu, DQ | 1 |
| Coleman, R; Drakeley, CJ; Jawara, M; Obisike, U; Pinder, M; Sutherland, CJ; Targett, GA; Walraven, G | 1 |
| Niagia, S | 1 |
| Fontanet, A; Looareesuwan, S; Nacher, M; Phumratanaprapin, W; Silachamroon, U; Singhasivanon, P; Wilairatana, P | 1 |
| Chim, P; Fandeur, T; Lim, P; Maciejewski, L; Nhem, S; Sem, R | 1 |
| Majori, G | 1 |
| Annerberg, A; Barends, M; Keola, S; Khanthavong, M; Lindegårdh, N; Mayxay, M; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; White, NJ; Yapom, R | 1 |
| Kyaw, MK; Lwin, S; Savran, O; Shahmanesh, M; Smithuis, F; White, NJ | 1 |
| Chim, P; Denis, MB; Fandeur, T; Lim, C; Lim, P; Nemh, S; Poravuth, Y; Seila, S; Sem, R; Socheat, D; Tsuyuoka, R | 1 |
| Hamedi, Y; Kojima, S; Looareesuwan, S; Safa, O; Tan-ariya, P; Zare, S | 1 |
| Atkin, S; Checchi, F; Ford, N; Hamour, S; Hook, C; Keus, K; Melaku, Y; Montgomery, J; Wambugu, J | 1 |
| Ampuero, J; Balkan, S; D'Alessandro, U; Denoncin, A; Dujardin, JC; Dunand, J; Fortes, F; Franco, J; Gaboulaud, V; Gillet, P; Guthmann, JP; Legros, D; Saraiva, N; Tobback, S; van Herp, M; van Overmeir, C | 1 |
| Dismukes, R; Franco-Paredes, C; Kozarsky, PE; Nicolls, D | 1 |
| Anderson, TJ; Brockman, A; Nair, S; Nosten, F; Paiphun, L; Qin, H; Singlam, S | 1 |
| Ahmad, F; Durrani, N; Graham, K; Leslie, T; Rahim, S; Rowland, M | 1 |
| Abuaku, B; Duah, N; Koram, KA; Quashie, N | 1 |
| Bangali, AM; Barends, M; Das, S; Faiz, AM; Kamal, M; Liem, L; Maung, UA; Peters, A; Rahman, M; Rahman, MR; van den Broek, IV | 1 |
| Agnamey, P; Brasseur, P; Cisse, M; Dumoulin, J; Gaye, O; Olliaro, P; Rigal, J; Taylor, WR | 1 |
| Garner, P; Jones, K; Taylor-Robinson, D | 1 |
| Adedeji, AA; Fateye, BA; Fehintola, FA; Gbotosho, GO; Happi, TC; Oduola, AM; Sowunmi, A; Tambo, E | 1 |
| Day, NP; Newton, PN; White, NJ | 1 |
| Baruah, S; Campbell, P; Narain, K; Rogers, CC | 1 |
| Akanmori, BD; Goka, BQ; Kurtzhals, JA; Ofori-Adjei, D; Quashie, NB | 1 |
| Arbe-Barnes, S; Brun, R; Kocken, CH; Matile, H; Scheurer, C; Thomas, AW; van der Wel, A; Wittlin, S | 1 |
| Agnamey, P; Brasseur, P; de Pecoulas, PE; Olliaro, P; Vaillant, M | 1 |
| Ahmed, ES; Elamin, SB; Elhassan, AH; Elmardi, KA; Malik, EM; Mannan, AA; Mohamed, TA; Mowien, RM | 1 |
| Fernández, FM; Grande Ortiz, M; Green, MD; Khounsaknalath, L; Manolin, O; Nettey, H; Newton, PN; Pamanivong, C; Villalva Rojas, O; Vongsack, L | 1 |
| Brockman, A; Chotivanich, K; Day, NP; Stepniewska, K; White, NJ | 1 |
| Anderson, T; Barends, M; Brockman, A; Jaidee, A; Mayxay, M; Nair, S; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Sudimack, D; White, NJ | 1 |
| Keola, S; Khanthavong, M; Mayxay, M; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Taylor, AM; White, NJ | 1 |
| Cao, YM; Chen, G; Feng, H; Guo, SY; Li, DM; Liu, YJ; Ma, SH; Wang, JC; Zheng, L | 1 |
| Andrianina, NN; Jahevitra, M; Ménard, D; Ramiandrasoa, Z; Randriamanantena, A; Rasoarilalao, N; Ratsimbasoa, A; Raveloson, A; Tuseo, L | 1 |
| Abuaku, B; Duah, NO; Koram, KA; Quashie, NB | 1 |
| Ariey, F; Bedja, SA; Rabarijaona, LP; Randrianarivelojosia, M; Robert, V; Tall, A | 1 |
| Afonso, A; Carter, R; Cheesman, S; Cravo, P; Creasey, A; Culleton, R; do Rosario, V; Fidock, DA; Hunt, P; Logan, J; McNae, I; Sidhu, AB; Valderramos, SG | 1 |
| Sharma, VP | 1 |
| Durrani, N; Kolaczinski, K; Rahim, S; Rowland, M | 1 |
| Nyunt, MM; Plowe, CV | 1 |
| Agbowai, C; Akogbeto, M; Coosemans, M; D'Alessandro, U; Erhart, A; Gazard, D; Massougbodji, A; Menten, J; Nahum, A; van Loen, H; Van Overmeir, C | 1 |
| Bissagnene, E; Die-Kakou, H; Jansen, FH; Lesaffre, E; Penali, LK; Zattera, MJ | 1 |
| Kreidenweiss, A; Kremsner, PG; Mordmüller, B | 1 |
| Benoit-Vical, F; Berry, A; Garcia-Alvarez, MC; Nicolau, ML; Olagnier, D; Soh, PN; Witkowski, B | 1 |
| Atta, H; Elmi, HH; Hassan, AM; Hassan, HM; Jibril, AM; Klena, JD; Waqar, BA; Warsame, M | 1 |
| Davis, TM; Gomorrai, PS; Griffin, S; Ilett, KF; Karunajeewa, HA; Kotab, K; Lautu, D; Law, I; Lin, E; Mueller, I; Oa, O; Page-Sharp, M; Salman, S; Senn, M; Siba, P; Suano, P; Tarongka, N; Ura, A; Wong, R | 1 |
| Ariey, F; Chim, P; Lim, P; Muth, S; Rogers, WO; Sem, R; Socheat, D; Tero, T; Wongsrichanalai, C | 1 |
| Anvikar, A; Bhatt, RM; Dua, VK; Kar, PK | 1 |
| Bélard, S; Kremsner, PG; Kurth, F; Mordmüller, B; Pongratz, P; Ramharter, M | 1 |
| Chaijaroenkul, W; Harnyuttanakorn, P; Mungthin, M; Na Bangchang, K; Suwandittakul, N | 1 |
| Alvarez-Doval, A; Angulo-Barturen, I; Gargallo-Viola, D; Garuti, H; Gómez, V; Ibáñez, J; Jiménez-Díaz, MB; Martínez, A; Mulet, T; Shultz, LD; Viera, S | 1 |
| Chaijaroenkul, W; Na-Bangchang, K; Wisedpanichkij, R | 1 |
| Giha, HA | 1 |
| Avabratha, KS; Chettiyar, LA; John, NP | 1 |
| Ariey, F; Beck, HP; Bouth, DM; Chim, P; Chy, S; Coppee, JY; Duong, S; Fandeur, T; Genton, B; Gobert, JG; Khim, N; Kim, S; Le Bras, J; Lim, P; Mercereau-Puijalon, O; Nhem, S; Ringwald, P; Rogers, WO; Sem, R; Wongsrichanalai, C; Yi, P | 1 |
| Boussinesq, M; Djomo, PN; Kamgno, J; Pion, SD; Thylefors, B | 1 |
| Balogun, ST; Fehintola, FA | 1 |
| Brady, NR; Efferth, T; Eils, R; Hamacher-Brady, A; Jennewein, N; Mora, R; Stein, HA; Toegel, I; Turschner, S | 1 |
| Arora, U; Dash, AP; Dhillon, GP; Meshnick, SR; Shah, NK; Valecha, N | 1 |
| Kaewpongsri, S; Kyle, DE; Leimanis, M; Lek-Uthai, U; Lwin, KM; Nosten, F; Phyo, AP; Renia, L; Russell, B; Sriprawat, K; Suwanarusk, R; Zwang, J | 1 |
| Bisvigou, U; Dinzouna Boutamba, SD; Ekomy, H; Lekana-Douki, JB; Toure-Ndouo, FS; Zang Edou, SE; Zatra, R | 1 |
| Borghini-Fuhrer, I; Duparc, S; Fleckenstein, L; Poravuth, Y; Purnama, A; Pyae Phyo, A; Rao, BH; Rueangweerayut, R; Shin, CS; Socheat, D; Tjitra, E; Uthaisin, C; Valecha, N | 1 |
| Terlouw, DJ; van Eijk, AM | 1 |
| Anstey, NM; Chan, L; Donaldson, S; Frederick, C; Jelip, J; Khoo, S; Ma, G; Menon, J; Rajahram, G; William, T; Yeo, TW | 1 |
| Sonkar, GK; Sonkar, SK; Uniyal, R | 1 |
| Afsharpad, M; Djadid, ND; Pirahmadi, S; Zakeri, S | 1 |
| Alonso, PL; Bassat, Q; Betuela, I; Kiniboro, B; Mueller, I; Robinson, LJ; Rosanas-Urgell, A; Siba, PM; Stanisic, D | 1 |
| Ali, I; Barends, M; Beshir, K; Durrani, N; Hallett, R; Kolaczinski, K; Lee, S; Leslie, T; Ord, R; Rowland, M | 1 |
| Anvikar, AR; Bhatt, RM; Dash, AP; Ghosh, SK; Kumar, A; Mohanty, SS; Pillai, CR; Sharma, B; Sharma, SK; Valecha, N | 1 |
| Anstey, NM; Chalfein, F; Haynes, RK; Kenangalem, E; Marfurt, J; Möhrle, JJ; Piera, KA; Prayoga, P; Price, RN; Sebayang, B; Wabiser, F; Wirjanata, G; Wittlin, S | 1 |
| Dzinjalamala, FK; Laufer, MK; Laurens, MB; Masonga, R; Nyirenda, OM; Plowe, CV; Stokes-Riner, A; Taylor, TE; Thesing, PC | 1 |
| Garner, P; Gelband, H; Graves, PM | 3 |
| Beeson, JG; Goodman, CD; Langer, C; McFadden, GI; Wilson, DW | 1 |
| Bagai, U; Rajan, A | 1 |
| Anderson, TJ; Jamsen, KM; Nair, S; Nosten, F; Price, RN; Simpson, JA; White, NJ; Woodrow, C; Zaloumis, S | 1 |
| Dondorp, AM; Faiz, MA; Hien, TT; Mokuolu, OA; Pukrittayakamee, S; White, NJ | 1 |
| Burkholder, B; Bustos, MD; Delacollette, C; Wongsrichanalai, C | 1 |
| Agbaje, EO; Aina, OO; Iribhogbe, OI; Oreagba, IA; Ota, AD | 1 |
| Choi, AR; Kim, JH; Kim, YK; Yoon, S | 1 |
| Chaijaroenkul, W; Muhamad, P; Na-Bangchang, K; Phompradit, P; Wisedpanichkij, R | 1 |
| Anvikar, AR; Das, MK; Gupta, R; Mishra, N; Rana, R; Shahi, B; Singh, S; Valecha, N | 1 |
| Chansiripornchai, N; Nithiuthai, S; Sasipreeyajan, J; Sohsuebngarm, D | 1 |
| Aguiar, AC; Amaral, NS; De Marco, L; Krettli, AU; Pereira, DB | 1 |
| Chen, L; Choi, K; Gibson, C; Huang, F; Keitany, GJ; Peng, X; Vignali, M; Wang, R | 1 |
| Bathurst, I; Chaorattanakawee, S; Ding, XC; Lanteri, CA; Lon, C; Rutvisuttinunt, W; Saunders, DL; Tyner, SD; Yingyuen, K | 1 |
| Gebru, T; Gerth, K; Held, J; Jansen, R; Kalesse, M; Mordmüller, B; Müller, R | 1 |
| Arboleda, M; Blair, S; Fernández, D; Garavito, G; Pabón, A; Segura, C | 1 |
| Anstey, NM; Barber, BE; Dhanaraj, P; Grigg, MJ; Menon, J; Price, RN; Rajahram, G; von Seidlein, L; William, T; Yeo, TW | 1 |
| Button, RW; Ercolano, E; Hanemann, CO; Hu, B; Lin, F; Luo, S; Vincent, JH | 1 |
| Adekunle, AI; Cromer, D; Davenport, MP; Luxemburger, C; McGready, R; Nosten, F; Pinkevych, M; White, LJ | 1 |
| Aime, E; Annoura, T; Arese, P; Capuccini, B; Chevalley-Maurel, S; Crisanti, A; Deroost, K; Franke-Fayard, BM; Janse, CJ; Khan, SM; Koster, AJ; Kroeze, H; Langhorne, J; Lin, JW; Mommaas-Kienhuis, AM; O'Toole, T; Prins, F; Ramesar, J; Ravelli, RB; Sajid, M; Schwarzer, E; Spaccapelo, R; Tanke, HJ; Van den Steen, PE | 1 |
| Blackie, MAL; de Kock, C; Pelly, SC; Smith, PJ; Taleli, L; van Otterlo, WAL | 1 |
| Auburn, S; Handayuni, I; Marfurt, J; Noviyanti, R; Pava, Z; Poespoprodjo, JR; Price, RN; To, S; Trianty, L; Wirjanata, G | 1 |
| Bannister-Tyrrell, M; Coosemans, M; d'Alessandro, U; Dierickx, S; Durnez, L; Erhart, A; Gerrets, R; Gryseels, C; Hausmann-Muela, S; Hoibak, S; Muela Ribera, J; Peeters Grietens, K; Phoeuk, P; Set, S; Sluydts, V; Suon, S; Tho, S; Trienekens, S; Uk, S | 1 |
| Anstey, NM; Barber, BE; Dhanaraj, P; Grigg, MJ; McCarthy, JS; Menon, J; Pasay, C; Price, RN; Rajahram, GS; von Seidlein, L; Wilkes, CS; William, T; Yeo, TW | 1 |
| Anto, F; Ayanful-Torgby, R; Dery, V; Duah, NO; Matrevi, SA; Quashie, NB | 1 |
| Aguirre-Acevedo, DC; Tamayo Perez, ME; Zuluaga-Idarraga, LM | 1 |
| Kamchonwongpaisan, S; Koonyosying, P; Songsungthong, W; Uthaipibull, C | 1 |
| Anstey, NM; Auburn, S; Barber, BE; Edstein, MD; Grigg, MJ; Menon, J; Price, RN; Rajahram, GS; Wilkes, CS; William, T; Yeo, TW | 1 |
| Amalvict, R; Benoit, N; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA | 1 |
| Cabral, L; Cristiano, ML; Lobo, L; Nogueira, F; Sousa, Bd | 1 |
| Abdul-Ghani, R; Alareqi, LMQ; Fong, MY; Lau, YL; Mahdy, MAK; Mahmud, R | 1 |
| Anstey, NM; Barber, BE; Grigg, MJ; William, T; Yeo, TW | 1 |
| Arez, AP; Berzosa, P; de Sousa, B; Guerra, M; Mendes, C; Ndong-Mabale, N; Neres, R; Salgueiro, P | 1 |
| Muhamad, P; Na-Bangchang, K; Phompradit, P; Thiengsusuk, A | 1 |
| Amalvict, R; Benoit, N; Briolant, S; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Kounta, MB; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA | 1 |
| Ataide, R; Beeson, JG; Boel, M; Drew, D; Fowkes, FJI; McGready, R; McLean, ARD; Nosten, F; Simpson, JA; Tsuboi, T | 1 |
| Aniweh, Y; Ansah, F; Awandare, GA; Chirawurah, JD; Duodu, S; Nyarko, PB | 1 |
| Aung, AA; Bancone, G; Carrara, VI; Cheah, PY; Chu, CS; Chue, AL; Imwong, M; Lwin, KM; Moore, KA; Nosten, F; Phyo, AP; Proux, S; Raksapraidee, R; San, T; Sriprawat, K; Tarning, J; Watson, J; White, NJ; Wiladphaingern, J; Win, HH; Winterberg, M | 1 |
| Araki, N; Cha'on, U; Guragain, D; Kobayashi, D; Sawanyawisuth, K; Seubwai, W; Silsinivanit, A; Vaeteewoottacharn, K; Wongkham, C; Wongkham, S | 1 |
| Ansbro, MR; Chookajorn, T; Chotivanich, K; de Cozar, C; Gamo, FJ; Kochakarn, T; Kotanan, N; Kümpornsin, K; Lee, MCS; Loesbanluechai, D; Sanz, LM; White, NJ; Wilairat, P | 1 |
| Abdel-Muhsin, AA; Abdelraheem, MH; Al Dhuhli, A; Al Hosni, A; Al Rubkhi, M; Al-Hamidhi, S; Babiker, HA; Bakhiet, AMA; Gadalla, A; Gismelseed, L; Kheir, A; Mukhtar, M; Naiem, A; Omer, S; Sultan, AA | 1 |
| Baird, JK; Cui, L; He, X; Huang, Y; Lu, Y; Pan, M; Pi, L; Qin, P; Qin, Y; Yang, Z; Zeng, W; Zhao, L; Zou, C | 1 |
| Obiebi, IP | 1 |
| Biagini, GA; Horrocks, PD; Mete, A; Sharma, R; Ullah, I; Wetzel, DM | 1 |
| Li, Z; Lin, F; Luo, SQ; Qiu, JL; Xiang, M; Zhu, YT | 1 |
| Lai, SK; Loo, HL; Preiser, PR; Sheriff, O; Sze, SK; Yaw, A | 1 |
| Al Khaja, KAJ; Sequeira, RP | 1 |
| Arwati, H; Basuki, DR; Ekasari, W; Wahyuni, TS | 1 |
| Rein, T | 1 |
| Asinya, M; Jeuronlon, MK; Kamara, P; Koko, VS; Kollie, A; Ma, L; Menard, D; Nyansaiye, P; Parwon, S; Pratt, OJ; Ringwald, P; Taweh, F; Tehmeh, L; Vonhm, B; Warsame, M | 1 |
| Daily, JP; Khan, N; Minuti, A | 1 |
| Andrianaranjaka, VHI; Jeannoda, V; Rakoto, DAD; Rakotomanga, TA; Rakotosaona, R; Ralinoro, F; Ramanantsahala, AD; Randrianarivo, RH; Ratsimbasoa, A; Ravaoarisoa, É | 1 |
| Duarte, D; Nunes, M; Ricardo, S; Vale, N | 1 |
| Bal, M; Das, A; Khan, N; Pati, S; Rana, R; Ranjit, M; Sandeepta, S | 1 |
| Chen, Y; Du, Q; Gong, Z; Pan, D; Peng, J; Sun, R; Wang, Q; Zhou, J | 1 |
17 review(s) available for chloroquine and artesunic acid
| Article | Year |
|---|---|
Combination therapy for malaria in Africa: hype or hope?
Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Cross-Cultural Comparison; Half-Life; Humans; Insecticide Resistance; Malaria; Mefloquine; Pyrimethamine; Self Medication; Sesquiterpenes; Sulfadoxine; Thailand | 2000 |
[Combined antimalarial therapy using artemisinin].
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2004 |
Malaria: uncomplicated, caused by Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Proguanil; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2005 |
Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Bayes Theorem; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Malaria; Mefloquine; Pyrimethamine; Randomized Controlled Trials as Topic; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Artemisinin derivatives for treatment of uncomplicated Plasmodium falciparum malaria in Sudan: too early for too much hope.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria, Falciparum; Pyrimethamine; Sudan; Sulfadoxine; Treatment Failure | 2010 |
Antimalarial drug resistance of Plasmodium falciparum in India: changes over time and space.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Geography; Humans; India; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Time Factors; Treatment Outcome | 2011 |
Azithromycin for treating uncomplicated malaria.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Atovaquone; Azithromycin; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Proguanil; Pyrimethamine; Randomized Controlled Trials as Topic; Sulfadoxine; Treatment Failure | 2011 |
Primaquine for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2012 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine | 2014 |
Monitoring antimalarial drug efficacy in the Greater Mekong Subregion: an overview of in vivo results from 2008 to 2010.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Directly Observed Therapy; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Quinolines | 2013 |
Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2014 |
Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2015 |
Therapeutic efficacy of alternative primaquine regimens to standard treatment in preventing relapses by Plasmodium vivax: A systematic review and meta-analysis.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Administration Schedule; Humans; Malaria, Vivax; Plasmodium vivax; Primaquine; Recurrence; Secondary Prevention | 2015 |
The Treatment of Plasmodium knowlesi Malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Coinfection; Humans; Malaria; Malaria, Falciparum; Plasmodium knowlesi | 2017 |
Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines.
Topics: Adult; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Chloroquine; Drug Combinations; Female; Humans; Malaria; Parasitemia; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinine; Sulfadoxine | 2021 |
Harnessing autophagy to fight SARS-CoV-2: An update in view of recent drug development efforts.
Topics: Antidepressive Agents; Antiviral Agents; Artesunate; Autophagy; Chloroquine; COVID-19 Drug Treatment; Drug Development; Drug Repositioning; Endoplasmic Reticulum; Endosomes; Humans; Hydroxychloroquine; Imatinib Mesylate; Infliximab; Intracellular Membranes; Ivermectin; Macrolides; Middle East Respiratory Syndrome Coronavirus; Niclosamide; Pandemics; RNA, Viral; SARS-CoV-2; Virus Replication | 2022 |
Diagnosis, Treatment, and Prevention of Malaria in the US: A Review.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Malaria; Malaria, Falciparum; Travel; Travel-Related Illness; United States | 2022 |
35 trial(s) available for chloroquine and artesunic acid
| Article | Year |
|---|---|
Efficacy of oral and intravenous artesunate in male Tanzanian adults with Plasmodium falciparum malaria and in vitro susceptibility to artemisinin, chloroquine, and mefloquine.
Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drugs, Chinese Herbal; Erythrocytes; Humans; Injections, Intravenous; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Parasitemia; Plasmodium falciparum; Recurrence; Sesquiterpenes; Tanzania | 1995 |
In vivo efficacy of chloroquine, halofantrine, pyrimethamine-sulfadoxine and qinghaosu (artesunate) in the treatment of malaria in Calabar, Nigeria.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Nigeria; Phenanthrenes; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Time Factors; Urban Health | 1996 |
Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria.
Topics: Administration, Rectal; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Female; Follow-Up Studies; Ghana; Humans; Infant; Injections, Intravenous; Malaria; Malaria, Cerebral; Male; Sesquiterpenes | 2001 |
Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.
Topics: Adolescent; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Gambia; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2001 |
Comparison of chloroquine with artesunate in the treatment of cerebral malaria in Ghanaian children.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Female; Ghana; Humans; Malaria, Cerebral; Male; Plasmodium falciparum; Sesquiterpenes | 2001 |
Therapeutic efficacies of artesunate-sulfadoxine-pyrimethamine and chloroquine-sulfadoxine-pyrimethamine in vivax malaria pilot studies: relationship to Plasmodium vivax dhfr mutations.
Topics: Adolescent; Adult; Animals; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Vivax; Male; Plasmodium vivax; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2002 |
The addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children delays, but does not prevent treatment failure.
Topics: Age Factors; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Gambia; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Sesquiterpenes; Treatment Failure | 2003 |
Treatment of uncomplicated falciparum malaria in southern Vietnam: can chloroquine or sulfadoxine-pyrimethamine be reintroduced in combination with artesunate?
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Humans; Malaria, Falciparum; Male; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Vietnam | 2003 |
Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes.
Topics: Acute Disease; Age Factors; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Gambia; Humans; Infant; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Prevalence; Sesquiterpenes; Treatment Failure | 2004 |
Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2004 |
Comparison of chloroquine, sulfadoxine/pyrimethamine, mefloquine and mefloquine-artesunate for the treatment of falciparum malaria in Kachin State, North Myanmar.
Topics: Adolescent; Adult; Age Distribution; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Myanmar; Pyrimethamine; Recurrence; Sesquiterpenes; Sulfadoxine; Treatment Failure | 2004 |
Therapeutic efficacy of artesunate in Plasmodium vivax malaria in Thailand.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Primaquine; Sesquiterpenes; Thailand; Treatment Outcome | 2004 |
Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Membrane Proteins; Membrane Transport Proteins; Protozoan Proteins; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2005 |
Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central Angola.
Topics: Amodiaquine; Angola; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure | 2005 |
Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum in Afghanistan.
Topics: Adolescent; Adult; Afghanistan; Aged; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasite Egg Count; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; Treatment Outcome | 2005 |
Comparative efficacy of antimalarial drugs including ACTs in the treatment of uncomplicated malaria among children under 5 years in Ghana.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Ghana; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2005 |
Efficacy of chloroquine + sulfadoxine--pyrimethamine, mefloquine + artesunate and artemether + lumefantrine combination therapies to treat Plasmodium falciparum malaria in the Chittagong Hill Tracts, Bangladesh.
Topics: Adolescent; Antimalarials; Artemether; Artemisinins; Artesunate; Bangladesh; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2005 |
Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Fever; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Parasitemia; Polymerase Chain Reaction; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; Treatment Outcome | 2005 |
A randomized trial comparing the efficacy of four treatment regimens for uncomplicated falciparum malaria in Assam state, India.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; India; Infant; Malaria, Falciparum; Male; Mefloquine; Prospective Studies; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2006 |
Thiamin deficiency and uncomplicated falciparum malaria in Laos.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Beriberi; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Enzyme Activation; Erythrocytes; Female; Humans; Infant; Laos; Malaria, Falciparum; Male; Middle Aged; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Thiamine Deficiency; Transketolase; Treatment Outcome | 2007 |
Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Madagascar; Malaria, Falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Efficacy of artesunate plus amodiaquine, artesunate plus sulfadoxine-pyrimethamine, and chloroquine plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union.
Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Comoros; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2007 |
Sulfadoxine-pyrimethamine plus artesunate compared with chloroquine for the treatment of vivax malaria in areas co-endemic for Plasmodium falciparum and P. vivax: a randomised non-inferiority trial in eastern Afghanistan.
Topics: Adolescent; Afghanistan; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; Humans; Malaria, Falciparum; Malaria, Vivax; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Adding artesunate to sulphadoxine-pyrimethamine greatly improves the treatment efficacy in children with uncomplicated falciparum malaria on the coast of Benin, West Africa.
Topics: Analysis of Variance; Anemia; Animals; Antimalarials; Artemisinins; Artesunate; Benin; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Fever; Follow-Up Studies; Humans; Infant; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Respiratory Tract Infections; Sesquiterpenes; Sulfadoxine; Time Factors; Treatment Outcome | 2007 |
A trial of combination antimalarial therapies in children from Papua New Guinea.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Kaplan-Meier Estimate; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Male; Proportional Hazards Models; Pyrimethamine; Quinolines; Recurrence; Sulfadoxine | 2008 |
A controlled trial to assess the effect of quinine, chloroquine, amodiaquine, and artesunate on Loa loa microfilaremia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amodiaquine; Animals; Anthelmintics; Artemisinins; Artesunate; Chloroquine; Humans; Loa; Loiasis; Middle Aged; Quinine; Young Adult | 2010 |
Comparative study of efficacy of artesunate plus cotrimoxazole and artesunate plus chloroquine in the treatment of malaria in Nigerian children: a preliminary report.
Topics: Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2010 |
Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Fever; Humans; Malaria, Vivax; Male; Middle Aged; Naphthyridines; Time Factors; Treatment Outcome; Young Adult | 2011 |
Defining Plasmodium falciparum treatment in South West Asia: a randomized trial comparing artesunate or primaquine combined with chloroquine or SP.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Pakistan; Patient Selection; Plasmodium falciparum; Polymerase Chain Reaction; Primaquine; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2012 |
A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Atovaquone; Azithromycin; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Endpoint Determination; Female; Genotyping Techniques; Humans; Infant; Longitudinal Studies; Malaria; Male; Proguanil | 2012 |
The efficacy of artesunate, chloroquine, doxycycline, primaquine and a combination of artesunate and primaquine against avian malaria in broilers.
Topics: Analysis of Variance; Animals; Antimalarials; Artemisinins; Artesunate; Body Weight; Chickens; Chloroquine; Doxycycline; Drug Combinations; Malaria, Avian; Parasitemia; Poultry Diseases; Primaquine; Treatment Outcome | 2014 |
A study protocol for a randomised open-label clinical trial of artesunate-mefloquine versus chloroquine in patients with non-severe Plasmodium knowlesi malaria in Sabah, Malaysia (ACT KNOW trial).
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Female; Humans; Malaria; Malaysia; Male; Mefloquine; Plasmodium knowlesi; Research Design; Severity of Illness Index | 2014 |
Artesunate-mefloquine versus chloroquine for treatment of uncomplicated Plasmodium knowlesi malaria in Malaysia (ACT KNOW): an open-label, randomised controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria; Malaysia; Male; Mefloquine; Middle Aged; Plasmodium knowlesi; Young Adult | 2016 |
Efficacy of Artesunate-mefloquine for Chloroquine-resistant Plasmodium vivax Malaria in Malaysia: An Open-label, Randomized, Controlled Trial.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Infant; Malaria, Vivax; Male; Mefloquine; Middle Aged; Plasmodium vivax; Treatment Outcome; Young Adult | 2016 |
Comparison of the Cumulative Efficacy and Safety of Chloroquine, Artesunate, and Chloroquine-Primaquine in Plasmodium vivax Malaria.
Topics: Adolescent; Adult; Antimalarials; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Vivax; Male; Middle Aged; Myanmar; Parasitemia; Plasmodium vivax; Primaquine; Recurrence; Thailand; Treatment Outcome; Young Adult | 2018 |
102 other study(ies) available for chloroquine and artesunic acid
| Article | Year |
|---|---|
[Sensitivity in vitro of Plasmodium falciparum to chloroquine, pyronaridine, artesunate and piperaquine in south Yunnan].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes | 1992 |
Decreased sensitivity of artesunate and chloroquine of Plasmodium falciparum infecting hemoglobin H and/or hemoglobin constant spring erythrocytes.
Topics: Animals; Artemisinins; Artesunate; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Erythrocytes; Hemoglobin H; Hemoglobins, Abnormal; Humans; Malaria; Plasmodium falciparum; Sesquiterpenes | 1989 |
[Effects of artesunate, pyronaridine and hydroxypiperaquine on chloroquine-sensitive and chloroquine-resistant isolates of Plasmodium falciparum in vitro].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes | 1988 |
[Development of a qinghaosu-resistant line of Plasmodium berghei ANKA and N strain].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Microbial; Malaria; Male; Mice; Plasmodium berghei; Primaquine; Pyrans; Sesquiterpenes | 1986 |
[Development of a piperaquine-resistant line of Plasmodium berghei K 173 strain].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes | 1985 |
[Sensitivity of Plasmodium falciparum to seven antimalarials in China-Laos border].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes | 1995 |
The iron environment in heme and heme-antimalarial complexes of pharmacological interest.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Heme; Hemeproteins; Hemin; Humans; Iron; Malaria; Quinine; Sesquiterpenes; Spectroscopy, Mossbauer | 1996 |
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs.
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes | 1996 |
In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes; Vietnam | 1997 |
In vitro sensitivity of Plasmodium falciparum to eight antimalarials in China-Myanmar and China-Lao PDR border areas.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; China; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Laos; Microbial Sensitivity Tests; Myanmar; Naphthyridines; Plasmodium falciparum; Quinine; Sesquiterpenes | 1997 |
Imported malaria: successful treatment of 31 patients in the era of chloroquine resistance.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Male; Middle Aged; Primaquine; Quinine; Retrospective Studies; Sesquiterpenes; Travel | 1999 |
Schizontocidal effects of oral artesunate on Plasmodium berghei in mice and P knowlesi in monkeys.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Female; Macaca mulatta; Malaria; Male; Mice; Plasmodium berghei; Plasmodium knowlesi; Sesquiterpenes | 1999 |
Parasitaemia and gametocytaemia after treatment with chloroquine, pyrimethamine/sulfadoxine, and pyrimethamine/sulfadoxine combined with artesunate in young Gambians with uncomplicated malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Cost-Benefit Analysis; Disease Transmission, Infectious; Drug Combinations; Female; Gambia; Gametogenesis; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Pyrimethamine; Random Allocation; Rural Health; Seasons; Sesquiterpenes; Sulfadoxine; Time Factors; Treatment Outcome | 2001 |
Potent antimalarial activities of polyether antibiotic, X-206.
Topics: Actinomycetales; Animals; Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Artesunate; Cell Death; Cell Line; Chloroquine; Drug Resistance; Embryo, Mammalian; Embryo, Nonmammalian; Ethers, Cyclic; Humans; Malaria; Mice; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes | 2001 |
[In vitro sensitivity of Plasmodium falciparum to chloroquine, piperaquine, pyronaridine and artesunate in Yuxi prefecture of Yunnan province].
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; In Vitro Techniques; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes | 1998 |
Resistant malaria in a neonate.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant, Newborn; Malaria, Falciparum; Mefloquine; Quinine; Risk Assessment; Sesquiterpenes; Severity of Illness Index; Treatment Outcome | 2002 |
Oral artesunate prevents Plasmodium berghei Anka infection in mice.
Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Therapy, Combination; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Plasmodium berghei; Sesquiterpenes | 2003 |
[Comparison of sensitivity of artesunate-sensitive and artesunate-resistant Plasmodium falciparum to chloroquine and amodiaquine].
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Drug Synergism; Plasmodium falciparum; Sesquiterpenes | 1999 |
Drug-resistant malaria in Bangladesh: an in vitro assessment.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Bangladesh; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes | 2003 |
[Factors affecting the in vitro microtest for drug sensitivity of Plasmodium falciparum].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood; Chloroquine; Humans; Malaria, Falciparum; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes | 2003 |
Ghana battles drug-resistant malaria with artesunate.
Topics: Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Malaria; Sesquiterpenes | 2004 |
Comparison of artesunate and chloroquine activities against Plasmodium vivax gametocytes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemisinins; Artesunate; Carrier State; Child; Child, Preschool; Chloroquine; Female; Humans; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Risk Assessment; Sesquiterpenes | 2004 |
The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Sesquiterpenes | 2004 |
In vitro monitoring of Plasmodium falciparum susceptibility to artesunate, mefloquine, quinine and chloroquine in Cambodia: 2001-2002.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Statistics, Nonparametric | 2005 |
Neurotoxicity due to antimalarial therapy associated with misdiagnosis of malaria.
Topics: Adult; Antimalarials; Anxiety; Artemisinins; Artesunate; Ataxia; Chloroquine; Diagnostic Errors; Humans; Malaria; Male; Sesquiterpenes; Tremor | 2005 |
Are transporter genes other than the chloroquine resistance locus (pfcrt) and multidrug resistance gene (pfmdr) associated with antimalarial drug resistance?
Topics: Animals; Antimalarials; Artemisinins; Artesunate; ATP-Binding Cassette Transporters; Chloroquine; Drug Resistance; Genes, MDR; Genes, Protozoan; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Sesquiterpenes | 2005 |
Economic evaluation of a policy change from single-agent treatment for suspected malaria to artesunate-amodiaquine for microscopically confirmed uncomplicated falciparum malaria in the Oussouye District of south-western Senegal.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Health Care Costs; Health Policy; Humans; Infant; Malaria, Falciparum; Male; Quinine; Rural Health; Senegal; Sesquiterpenes | 2005 |
Misattribution of central nervous system dysfunction to artesunate.
Topics: Antimalarials; Artemisinins; Artesunate; Central Nervous System Diseases; Chloroquine; Humans; Sesquiterpenes | 2005 |
Factors contributing to the development of anaemia in Plasmodium falciparum malaria: what about drug-resistant parasites?
Topics: Amodiaquine; Anemia; Animals; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria; Plasmodium falciparum; Sesquiterpenes | 2006 |
Plasmodium vivax: in vitro susceptibility of blood stages to synthetic trioxolane compounds and the diamidine DB75.
Topics: Animals; Antimalarials; Aotidae; Artemether; Artemisinins; Artesunate; Benzamidines; Chloroquine; Drug Resistance; Heterocyclic Compounds, 1-Ring; Inhibitory Concentration 50; Malaria, Vivax; Parasitemia; Peroxides; Plasmodium falciparum; Plasmodium vivax; Sesquiterpenes; Spiro Compounds; Time Factors | 2006 |
Plasmodium falciparum in vitro susceptibility to antimalarial drugs in Casamance (southwestern Senegal) during the first 5 years of routine use of artesunate-amodiaquine.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Plasmodium falciparum; Sesquiterpenes | 2006 |
From chloroquine to artemisinin-based combination therapy: the Sudanese experience.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Policy; Humans; Lumefantrine; Malaria, Falciparum; Product Surveillance, Postmarketing; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Time Factors | 2006 |
Use of refractometry and colorimetry as field methods to rapidly assess antimalarial drug quality.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Chromatography, High Pressure Liquid; Colorimetry; Indicators and Reagents; Quality Control; Quinine; Reference Standards; Refractometry; Sesquiterpenes; Spectrophotometry, Ultraviolet; Sulfadoxine | 2007 |
Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC50 values using a Bayesian approach.
Topics: Algorithms; Animals; Antimalarials; Artemisinins; Artesunate; Bayes Theorem; Chloroquine; Computer Simulation; Dose-Response Relationship, Drug; Drug Resistance; False Positive Reactions; Inhibitory Concentration 50; Mefloquine; Models, Biological; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes | 2007 |
In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Protozoan Proteins; Sesquiterpenes | 2007 |
Plasmodium yoelii: influence of antimalarial treatment on acquisition of immunity in BALB/c and DBA/2 mice.
Topics: Animals; Antibodies, Protozoan; Antimalarials; Artemisinins; Artesunate; Chloroquine; Female; Immunoglobulin G; Interferon-gamma; Malaria; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Parasitemia; Plasmodium yoelii; Recurrence; Sesquiterpenes | 2007 |
The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Infant; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes | 2007 |
Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites.
Topics: Amino Acid Sequence; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Female; Genes, Protozoan; Humans; Mice; Mice, Inbred CBA; Models, Molecular; Mutation; Parasitic Sensitivity Tests; Plasmodium chabaudi; Sesquiterpenes; Ubiquitin | 2007 |
Battling the malaria iceberg with chloroquine in India.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Delivery of Health Care; Drug Combinations; Drug Resistance; Humans; India; Malaria; Preventive Health Services; Pyrimethamine; Sesquiterpenes; Socioeconomic Factors; Sulfadoxine; Time Factors | 2007 |
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Global Health; Half-Life; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2007 |
Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Gabon; Humans; Infant; Inhibitory Concentration 50; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Proteasome Inhibitors | 2008 |
In vitro and in vivo properties of ellagic acid in malaria treatment.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Chloroquine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ellagic Acid; Erythrocytes; Female; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Mice; Mice, Inbred Strains; Molecular Structure; Molecular Weight; Parasitemia; Parasitic Sensitivity Tests; Plasmodium; Plasmodium falciparum; Schizonts; Trophozoites | 2009 |
Efficacy of monotherapies and artesunate-based combination therapies in children with uncomplicated malaria in Somalia.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Pyrimethamine; Somalia; Sulfadoxine; Treatment Outcome | 2009 |
Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia.
Topics: Adult; Animals; Antimalarials; Artemisinins; Artesunate; Cambodia; Child; Chloroquine; Drug Therapy, Combination; Female; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Multidrug Resistance-Associated Proteins; Parasitemia; Plasmodium falciparum; Polymerase Chain Reaction; Survival Analysis; Treatment Failure | 2009 |
Malaria - change in therapeutic policy.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2009 |
In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays.
Topics: Administration, Oral; Adolescent; Animals; Antigens, Protozoan; Antimalarials; Artemisinins; Artesunate; Biological Assay; Child; Child, Preschool; Chloroquine; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Female; Gabon; Humans; Infant; Malaria, Falciparum; Male; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinine; Regression Analysis | 2009 |
Drug resistance and in vitro susceptibility of Plasmodium falciparum in Thailand during 1988-2003.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Thailand | 2009 |
Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Erythrocytes; Humans; Interleukin Receptor Common gamma Subunit; Kinetics; Malaria, Falciparum; Mice; Mice, Inbred NOD; Mice, SCID; Pyridones; Pyrimethamine | 2009 |
Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Gene Dosage; Genetic Markers; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Myanmar; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Thailand | 2010 |
Oral artesunate for neonatal malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Therapy, Combination; Humans; Infant, Newborn; Malaria, Vivax; Male; Plasmodium vivax; Treatment Outcome | 2010 |
Decreased in vitro susceptibility of Plasmodium falciparum isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001 to 2007.
Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Drug Resistance, Bacterial; Geographic Information Systems; In Vitro Techniques; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Oligonucleotide Array Sequence Analysis; Plasmodium falciparum; Point Mutation; Polymorphism, Single Nucleotide; Quinine | 2010 |
Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production.
Topics: Antimalarials; Apoptosis; Artemisinins; Artesunate; Breast Neoplasms; Cell Line, Tumor; Chloroquine; Enzyme Inhibitors; Female; Humans; Iron; Lysosomes; Macrolides; Mitochondria; Mitochondrial Membranes; Permeability; Reactive Oxygen Species | 2011 |
The presence of leukocytes in ex vivo assays significantly increases the 50-percent inhibitory concentrations of artesunate and chloroquine against Plasmodium vivax and Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Humans; Inhibitory Concentration 50; Leukocytes; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax | 2011 |
Increased prevalence of the Plasmodium falciparum Pfmdr1 86N genotype among field isolates from Franceville, Gabon after replacement of chloroquine by artemether-lumefantrine and artesunate-mefloquine.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Gabon; Genotype; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitemia; Plasmodium falciparum; Polymorphism, Genetic; Prevalence; Protozoan Proteins | 2011 |
Severe Plasmodium knowlesi malaria in a tertiary care hospital, Sabah, Malaysia.
Topics: Acute Kidney Injury; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Ethanolamines; Female; Fluorenes; Hospitals, Urban; Humans; Lumefantrine; Malaria; Malaysia; Microscopy; Middle Aged; Parasitemia; Patient Selection; Plasmodium knowlesi; Polymerase Chain Reaction; Quinine; Respiratory Distress Syndrome; Severity of Illness Index; Shock; Survival Rate | 2011 |
Three unusual presentations of plasmodium vivax malaria.
Topics: Adult; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Female; Humans; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Primaquine; Respiratory Distress Syndrome; Shock; Splenic Infarction; Treatment Outcome | 2011 |
Molecular assessment of dhfr/dhps mutations among Plasmodium vivax clinical isolates after introduction of sulfadoxine/pyrimethamine in combination with artesunate in Iran.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Dihydropteroate Synthase; DNA, Protozoan; Drug Combinations; Drug Resistance; Haplotypes; Humans; Infant; Iran; Malaria, Vivax; Middle Aged; Mutation; Plasmodium vivax; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Young Adult | 2012 |
Tolerability and safety of primaquine in Papua New Guinean children 1 to 10 years of age.
Topics: Aging; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Cohort Studies; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; New Guinea; Primaquine | 2012 |
In vitro assessment of drug resistance in Plasmodium falciparum in five States of India.
Topics: Amodiaquine; Artemisinins; Artesunate; Biomarkers, Pharmacological; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; India; Mefloquine; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins | 2012 |
Comparative ex vivo activity of novel endoperoxides in multidrug-resistant plasmodium falciparum and P. vivax.
Topics: Adamantane; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Heterocyclic Compounds, 1-Ring; Microbial Sensitivity Tests; Peroxides; Plasmodium falciparum; Plasmodium vivax; Quinolines; Spiro Compounds | 2012 |
Defining the timing of action of antimalarial drugs against Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Flow Cytometry; High-Throughput Screening Assays; Hydroxamic Acids; Inhibitory Concentration 50; Mefloquine; Merozoites; Plasmodium falciparum; Quinine; Quinolines; Schizonts; Time Factors | 2013 |
Antimalarial potential of China 30 and Chelidonium 30 in combination therapy against lethal rodent malaria parasite: Plasmodium berghei.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chelidonium; Chloroquine; Cinchona; Female; Homeopathy; Malaria; Male; Materia Medica; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Phytotherapy; Plant Extracts; Plasmodium berghei; Pyrimethamine | 2013 |
Nonlinear mixed-effects modelling of in vitro drug susceptibility and molecular correlates of multidrug resistant Plasmodium falciparum.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Ethanolamines; Fluorenes; Lumefantrine; Mefloquine; Models, Statistical; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protozoan Proteins | 2013 |
Oxidative stress and micronutrient therapy in malaria: an in vivo study in Plasmodium berghei infected mice.
Topics: Animals; Antioxidants; Artemisinins; Artesunate; Chloroquine; Dose-Response Relationship, Drug; Female; Hemolysis; Malaria; Male; Mice; Micronutrients; Oxidative Stress; Plasmodium berghei; Selenium; Vitamin A; Vitamin E; Zinc | 2013 |
Co-treatment with the anti-malarial drugs mefloquine and primaquine highly sensitizes drug-resistant cancer cells by increasing P-gp inhibition.
Topics: Antimalarials; Antineoplastic Agents; Apoptosis; Artemisinins; Artesunate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chloroquine; Doxycycline; Drug Resistance, Neoplasm; Humans; Mefloquine; Primaquine; Verapamil; Vinblastine | 2013 |
Four years' monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Seasons; Thailand; Time Factors | 2014 |
Insights following change in drug policy: a descriptive study for antimalarial prescription practices in children of public sector health facilities in Jharkhand state of India.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Health Facilities; Humans; Inappropriate Prescribing; India; Infant; Malaria; Male; Practice Patterns, Physicians'; Prescriptions; Prospective Studies; Public Sector; Pyrimethamine; Retrospective Studies; Sulfadoxine | 2013 |
Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti-malarials and gene characterization in Rondônia, West Amazon, Brazil.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Brazil; Chloroquine; DNA, Protozoan; Drug Resistance; Female; Genotype; Humans; Inhibitory Concentration 50; Malaria; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation, Missense; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins | 2014 |
Artesunate versus chloroquine infection-treatment-vaccination defines stage-specific immune responses associated with prolonged sterile protection against both pre-erythrocytic and erythrocytic Plasmodium yoelii infection.
Topics: Animals; Anopheles; Antibodies, Protozoan; Antimalarials; Artemisia; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Female; Malaria; Malaria Vaccines; Mice; Mice, Inbred BALB C; Phytotherapy; Plasmodium yoelii; Sporozoites; Time Factors; Vaccines, Attenuated | 2014 |
Ex vivo activity of endoperoxide antimalarials, including artemisone and arterolane, against multidrug-resistant Plasmodium falciparum isolates from Cambodia.
Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Heterocyclic Compounds, 1-Ring; Parasitic Sensitivity Tests; Peroxides; Plasmodium falciparum; Spiro Compounds | 2014 |
Antimalarial activity of the myxobacterial macrolide chlorotonil a.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Hydrocarbons, Chlorinated; Macrolides; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Myxococcales; Parasitemia; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum | 2014 |
In vitro susceptibility of Plasmodium vivax to antimalarials in Colombia.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Colombia; Drug Resistance; Malaria, Vivax; Mefloquine; Parasitic Sensitivity Tests; Plasmodium vivax; Quinine | 2014 |
Artesunate induces necrotic cell death in schwannoma cells.
Topics: Apoptosis; Artemisinins; Artesunate; Autophagy; Cell Line, Tumor; Chloroquine; Drug Synergism; Free Radical Scavengers; Humans; Necrosis; Neurilemmoma; Nuclear Pore Complex Proteins; Reactive Oxygen Species; RNA-Binding Proteins | 2014 |
Modeling the dynamics of Plasmodium vivax infection and hypnozoite reactivation in vivo.
Topics: Aged; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Female; Humans; Liver; Malaria, Vivax; Male; Models, Biological; Papua New Guinea; Plasmodium vivax; Primaquine; Sporozoites; Thailand; Torpor | 2015 |
Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Cytoplasm; Drug Resistance; Erythrocytes; Female; Gene Deletion; Genes, Reporter; Hemeproteins; Hemoglobins; Malaria; Male; Mice; Mice, Inbred BALB C; Mutation; Plasmodium berghei; Reticulocytes | 2015 |
In vitro antiplasmodial activity of triazole-linked chloroquinoline derivatives synthesized from 7-chloro-N-(prop-2-yn-1-yl)quinolin-4-amine.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Click Chemistry; Drug Evaluation, Preclinical; Drug Resistance; Molecular Structure; Plasmodium falciparum; Triazoles | 2015 |
Expression of Plasmodium vivax crt-o Is Related to Parasite Stage but Not Ex Vivo Chloroquine Susceptibility.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Erythrocytes; Fructose-Bisphosphate Aldolase; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Life Cycle Stages; Malaria, Vivax; Mefloquine; Membrane Transport Proteins; Plasmodium vivax; Protozoan Proteins; Quinolines; Transcription, Genetic; Tubulin | 2016 |
Characterizing Types of Human Mobility to Inform Differential and Targeted Malaria Elimination Strategies in Northeast Cambodia.
Topics: Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Disease Eradication; Health Surveys; Humans; Insect Vectors; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Plasmodium falciparum; Plasmodium vivax; Transients and Migrants | 2015 |
An improved SYBR Green-1-based fluorescence method for the routine monitoring of Plasmodium falciparum resistance to anti-malarial drugs.
Topics: Antimalarials; Artemisinins; Artesunate; Benzothiazoles; Child; Child, Preschool; Chloroquine; Diamines; Drug Resistance; Fluorometry; Humans; Inhibitory Concentration 50; Mefloquine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Staining and Labeling | 2015 |
Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Female; Glutamate-Cysteine Ligase; Glutathione; Malaria; Mice; Mice, Inbred BALB C; Plasmodium berghei; Pyrimethamine; Sulfadoxine | 2016 |
Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Lumefantrine; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Quinine; Quinolines; Senegal; Ubiquitin-Protein Ligases | 2016 |
Highly active ozonides selected against drug resistant malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Female; Humans; Malaria, Falciparum; Mefloquine; Mice; Parasitemia; Plasmodium falciparum | 2016 |
Molecular markers associated with resistance to commonly used antimalarial drugs among Plasmodium falciparum isolates from a malaria-endemic area in Taiz governorate-Yemen during the transmission season.
Topics: Alleles; Antimalarials; Artemisinins; Artesunate; Chloroquine; Cross-Sectional Studies; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Genotype; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Yemen | 2016 |
Plasmodium falciparum Genetic Diversity in Continental Equatorial Guinea before and after Introduction of Artemisinin-Based Combination Therapy.
Topics: Amodiaquine; Antigens, Protozoan; Antimalarials; Artemisinins; Artesunate; Chloroquine; DNA Copy Number Variations; Drug Combinations; Drug Resistance; Equatorial Guinea; Female; Genetic Loci; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Male; Membrane Transport Proteins; Microsatellite Repeats; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2017 |
In vitro sensitivity of antimalarial drugs and correlation with clinico-parasitological response following treatment with a 3-day artesunate-mefloquine combination in patients with falciparum malaria along the Thai-Myanmar border.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Myanmar; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Thailand; Young Adult | 2017 |
Association between Polymorphisms in the Pf
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal | 2017 |
Antibody Responses to
Topics: Adaptive Immunity; Antibodies, Protozoan; Antimalarials; Artemisinins; Artesunate; Chloroquine; Cohort Studies; Disease Resistance; Disease Susceptibility; Female; Humans; Immunoglobulin G; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Merozoite Surface Protein 1; Parasitemia; Parturition; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Proportional Hazards Models; Risk; Time Factors | 2017 |
Antimalarial activity of Malaria Box Compounds against Plasmodium falciparum clinical isolates.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Ghana; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum | 2017 |
Artesunate and chloroquine induce cytotoxic activity on cholangiocarcinoma cells via different cell death mechanisms.
Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Artesunate; Bile Duct Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Chloroquine; Cholangiocarcinoma; Humans | 2018 |
Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine.
Topics: Antimalarials; Artesunate; Aspartic Acid Endopeptidases; Cambodia; Chloroquine; Drug Resistance; Gene Dosage; Inhibitory Concentration 50; Microbial Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinolines | 2019 |
Evolution of Plasmodium falciparum drug resistance genes following artemisinin combination therapy in Sudan.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; DNA, Protozoan; Drug Resistance; Drug Therapy, Combination; Genetic Markers; Genotype; Humans; Lumefantrine; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sudan; Sulfadoxine | 2019 |
Multiple relapses of Plasmodium vivax malaria acquired from West Africa and association with poor metabolizer CYP2D6 variant: a case report.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Cytochrome P-450 CYP2D6; Ghana; Humans; Inactivation, Metabolic; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Primaquine; Recurrence | 2019 |
Adherence to antimalarial drug policy among doctors in Delta State, Nigeria: implications for malaria control.
Topics: Adult; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Chloroquine; Drug Resistance, Microbial; Female; Guideline Adherence; Health Policy; Humans; Malaria, Falciparum; Male; Middle Aged; Nigeria; Plasmodium falciparum; Practice Guidelines as Topic; Practice Patterns, Physicians'; Quinine; Surveys and Questionnaires; Young Adult | 2019 |
The relative rate of kill of the MMV Malaria Box compounds provides links to the mode of antimalarial action and highlights scaffolds of medicinal chemistry interest.
Topics: Antimalarials; Artesunate; Chloroquine; Drug Development; Plasmodium falciparum | 2020 |
Enhanced lysosomal function is critical for paclitaxel resistance in cancer cells: reversed by artesunate.
Topics: Antineoplastic Agents; Artesunate; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cathepsins; Cell Death; Cell Line, Tumor; Cell Proliferation; Chloroquine; Chromans; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Gene Knockdown Techniques; Humans; Lysosomes; Paclitaxel | 2021 |
Plasmodium falciparum replication factor C subunit 1 is involved in genotoxic stress response.
Topics: Antimalarials; Artesunate; Cell Death; Chloroquine; DNA Damage; DNA Repair; DNA Replication; DNA, Protozoan; Erythrocytes; Gene Expression Regulation; Host-Parasite Interactions; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Reactive Oxygen Species; Replication Protein C | 2021 |
Antiplasmodial activity of Ethanolic extract of Cassia spectabilis DC leaf and its inhibition effect in Heme detoxification.
Topics: Animals; Antimalarials; Artesunate; Cassia; Chloroquine; Heme; Ketones; Malaria; Male; Mice, Inbred BALB C; Phytotherapy; Piperidines; Plant Extracts; Plant Leaves; Plasmodium berghei; Plasmodium falciparum | 2021 |
Artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Child; Chloroquine; DNA Copy Number Variations; Female; Humans; Liberia; Malaria; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Pregnancy | 2022 |
[Pcr-rflp genotyping of
Topics: Amodiaquine; Artesunate; Child; Chloroquine; Drug Resistance; Genotype; Humans; Madagascar; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Protozoan Proteins | 2022 |
Combination of Antimalarial and CNS Drugs with Antineoplastic Agents in MCF-7 Breast and HT-29 Colon Cancer Cells: Biosafety Evaluation and Mechanism of Action.
Topics: Adenosine Diphosphate; Antimalarials; Antineoplastic Agents; Artesunate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benztropine; Breast Neoplasms; Cell Line, Tumor; Chloroquine; Colonic Neoplasms; Containment of Biohazards; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Fluoxetine; Fluphenazine; Humans; Ki-67 Antigen; MCF-7 Cells; Michigan; NF-kappa B; Paclitaxel; Poly(ADP-ribose) Polymerase Inhibitors; Ribose; Sertraline; Thioridazine | 2022 |
Molecular surveillance of anti-malarial drug resistance genes in Plasmodium falciparum isolates in Odisha, India.
Topics: Antimalarials; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Humans; India; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2022 |
Dual-targeting of artesunate and chloroquine to tumor cells and tumor-associated macrophages by a biomimetic PLGA nanoparticle for colorectal cancer treatment.
Topics: Animals; Artesunate; Biomimetics; Cell Line, Tumor; Chloroquine; Colorectal Neoplasms; Mice; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Tumor Microenvironment; Tumor-Associated Macrophages | 2023 |