Compounds > chloroquine

chloroquine and artesunate

chloroquine has been researched along with artesunate in 111 studies

Research

Studies (111)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (11.71)29.6817
2010's87 (78.38)24.3611
2020's11 (9.91)2.80

Authors

AuthorsStudies
Croft, SL; Jung, M; Kendrick, H; Lee, K; Robinson, BL1
Croft, SL; Jung, H; Jung, M; Kendrick, H; Lee, K; Yardley, V1
Brun, R; Charman, SA; Charman, WN; Chiu, FC; Chollet, J; Dong, Y; Dorn, A; Karle, JM; Matile, H; Santo Tomas, J; Scheurer, C; Scorneaux, B; Snyder, C; Tang, Y; Urwyler, H; Vennerstrom, JL; Wang, X; Wittlin, S1
Benoit-Vical, F; Berry, A; Cazelles, J; Dechy-Cabaret, O; Deymier, C; Lelièvre, J; Loup, C; Magnaval, JF; Meunier, B; Robert, A1
Benoit-Vical, F; Lelièvre, J; Loup, C; Meunier, B1
Anstey, NM; Brockman, A; Chalfein, F; Cheng, Q; Kenangalem, E; Piera, K; Prasetyorini, B; Prayoga, P; Price, RN; Russell, B; Sugiarto, P; Suwanarusk, R; Tjitra, E1
Becker, K; Davioud-Charvet, E; Friebolin, W; Furrer, J; Jannack, B; Lanzer, M; Oeser, T; Sanchez, CP; Wenzel, N; Yardley, V1
Lombardo, F; Obach, RS; Waters, NJ1
Andrews, KT; Anstey, NM; Boonma, P; Gardiner, DL; Lek-Uthai, U; Machunter, B; McCarthy, JS; Nosten, F; Piera, KA; Price, RN; Ruengweerayut, R; Russell, B; Skinner-Adams, TS; Suwanarusk, R1
Anstey, NM; Chalfien, F; Hasugian, AR; Kenangalem, E; Marfurt, J; Penttinen, PM; Piera, KA; Price, RN; Purba, HL; Ratcliff, A; Russell, B; Siswantoro, H; Tjitra, E; Wuwung, RM1
Alvarez-Doval, A; Angulo-Barturen, I; Gargallo-Viola, D; Garuti, H; Gómez, V; Ibáñez, J; Jiménez-Díaz, MB; Martínez, A; Mulet, T; Shultz, LD; Viera, S1
Bertinaria, M; Croft, SL; Crosetti, M; Fruttero, R; Gasco, A; Guglielmo, S; Rolando, B; Yardley, V1
Anquetin, G; Biot, C; Dive, D; Dubar, F; Khalife, J; Pradines, B1
Brun, R; Charman, SA; Charman, WN; Chollet, J; Creek, DJ; Dong, Y; Dorn, A; Koltun, M; Matile, H; Morizzi, J; Padmanilayam, M; Santo Tomas, J; Scheurer, C; Snyder, C; Sriraghavan, K; Tang, Y; Urwyler, H; Vennerstrom, JL; Wang, X; Wittlin, S1
Charman, SA; Charman, WN; Chiu, FC; Chollet, J; Dong, Y; Dorn, A; Johnson, LM; Matile, H; Morizzi, J; Scheurer, C; Snyder, C; Tang, Y; Tomas, JS; Urwyler, H; Vennerstrom, JL; Wittlin, S; Zhou, L1
Barragán, MJ; Benoit-Vical, F; Berry, A; Laurent, V; Lelièvre, J; Su, XZ; Witkowski, B1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Brun, R; Chitnumsub, P; Dartois, V; Diagana, TT; Goh, A; Kamchonwongpaisan, S; Keller, TH; Kiara, SM; Lakshminarayana, SB; Ma, NL; Maneeruttanarungroj, C; Nzila, A; Rottmann, M; Taweechai, S; Weaver, M; Wittlin, S; Wong, J; Yeung, BK; Yuthavong, Y; Zou, B1
Biagini, GA; Chandramohanadas, R; Darling, C; DeGrado, WF; Diamond, SL; Fisher, N; Greenbaum, DC; Jing, H; Jo, H; Lucumi, E; Napper, AD; Shone, AE; Ward, SA1
Ang, SH; Brun, R; Dartois, V; Diagana, TT; Fischli, C; Francotte, E; Goh, A; Henson, K; Keller, TH; Keller-Maerki, S; Krastel, P; Kuhen, K; Lakshminarayana, SB; Leong, SY; Petersen, F; Plouffe, D; Rottmann, M; Schmitt, EK; Tan, J; Wagner, T; Winzeler, EA; Wong, J; Yeung, BK; Zou, B1
Beck, HP; Brun, R; Cohen, SB; Dartois, V; Dharia, NV; Diagana, TT; Fidock, DA; Goh, A; González-Páez, GE; Jegla, T; Keller, TH; Lakshminarayana, SB; Lee, MC; McNamara, C; Nosten, F; Plouffe, DM; Renia, L; Rottmann, M; Russell, B; Schmitt, EK; Seitz, P; Spencer, KR; Suwanarusk, R; Tan, J; Winzeler, EA; Yeung, BK; Zou, B1
Anstey, NM; Chalfein, F; Kenangalem, E; Marfurt, J; Piera, KA; Price, RN; Russell, B; Tjitra, E1
Anstey, NM; Chalfein, F; Ebsworth, EP; Kenangalem, E; Marfurt, J; Piera, KA; Prasetyorini, B; Price, RN; Ratcliff, A; Russell, B; Siswantoro, H; Tjitra, E; Wuwung, M1
Andrews, KT; Anstey, NM; Chalfein, F; Fairlie, DP; Kenangalem, E; Marfurt, J; Piera, KA; Prayoga, P; Price, RN; Tjitra, E; Wabiser, F1
Birrell, GW; Chavchich, M; Cobbe, M; Edstein, MD; Kissell, R; Ovenden, SP1
Bathurst, I; Buckner, FS; Burrows, J; Charman, SA; Charman, WN; Creason, S; Deng, X; El Mazouni, F; Floyd, DM; Gujjar, R; Matthews, D; Phillips, MA; Rathod, PK; Shackleford, DM; White, J; White, KL1
Ang, HQ; Borboa, R; Brun, R; Caldwell, C; Chang, J; Chatterjee, AK; Chen, Z; Dartois, V; Diagana, T; Ek, J; Fischli, C; Francek, C; Gagaring, K; Glynne, R; Goh, A; Hollenbeck, T; Isbell, J; Kang, ML; Keller, T; Kuhen, K; Lakshminarayana, SB; Li, C; Lin, X; Liu, F; Nagle, A; Plouffe, D; Rottmann, M; Skolnik, S; Tan, M; Tan, W; Tully, DC; Tuntland, T; Wang, J; Winzeler, E; Wu, J; Wu, T; Ye, N; Zeng, P1
Dussault, PH; Rottman, M; Schiaffo, CE; Wittlin, S1
Angulo-Barturen, I; Bathurst, I; Bhamidipati, R; Burrows, JN; Charman, SA; Charman, WN; Coteron, JM; Deng, X; El Mazouni, F; Esquivias, J; Ferrer, SB; Floyd, D; Gamo, FJ; Goldsmith, EJ; Jiménez-Díaz, MB; Katneni, K; Kokkonda, S; Koltun, M; Marco, M; Matthews, D; Phillips, MA; Rathod, PK; Shackleford, DM; White, J; White, KL1
Burrows, JN; Charman, SA; Chibale, K; Douelle, F; Feng, TS; González Cabrera, D; Nchinda, AT; Ryan, E; Waterson, D; White, KL; Wittlin, S; Witty, MJ; Wu, Q; Younis, Y1
Chandrashekar, G; Chatterji, D; Meng, L; Robinson, K; Zhu, S1
Balzarini, J; Bharatam, PV; Chibale, K; Kaur, H; Little, S; Singh, K1
Alper, PB; Borboa, R; Brun, R; Caldwell, C; Chang, J; Chatterjee, AK; Chen, Z; Chuan, T; Diagana, TT; Ek, J; Fischli, C; Francek, C; Gagaring, K; Glynne, R; Hollenbeck, T; Isbell, J; Kuhen, K; Lakshminarayana, SB; Li, C; Lin, X; Liu, B; Liu, F; Nagle, A; Plouffe, D; Rottmann, M; Skolnik, S; Tully, DC; Tuntland, T; Wang, J; Winzeler, EA; Wu, T1
Bowman, JD; Brodie, PJ; Callmander, MW; Cassera, MB; Gorka, A; Harinantenaina, L; Kingston, DG; Rakotobe, E; Randrianaivo, R; Rasamison, VE; Roepe, PD; Slebodnick, C1
Charman, SA; Chiu, FC; Chollet, J; Dong, Y; Katneni, K; Mannila, J; Morizzi, J; Ryan, E; Santo Tomas, J; Scheurer, C; Snyder, C; Steuten, J; Vennerstrom, JL; Wang, X; Wittlin, S1
Biamonte, MA; Le Roch, KG; Wanner, J1
Balzarini, J; Chibale, K; Kaur, H; Singh, K1
Appel, J; Bouraoui, A; Croft, S; Dellai, A; Nefzi, A1
Avery, VM; Baell, JB; Duffy, S; Hutton, CA; Klonis, N; Lucantoni, L; Teguh, SC; Tilley, L1
Avery, VM; Sykes, ML1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Amewu, RK; Burrell-Saward, H; Chadwick, J; Hussain, A; Janneh, O; Miguel, C; O'Neill, PM; Panda, S; Rinki, R; Vivas, L; Ward, SA1
Chibale, K; D'hooghe, M; de Kock, C; Desmet, T; Smith, PJ; Tran, HG; Vandekerckhove, S1
Avery, VM; Charman, SA; Chibale, K; Douelle, F; Duffy, S; Gonzàlez Cabrera, D; Le Manach, C; March, C; Nchinda, AT; Ryan, E; Street, LJ; Taylor, D; Waterson, D; White, KL; Wiesner, L; Wittlin, S; Witty, MJ; Younis, Y1
Andrews, KT; Avery, VM; Duffy, S; Hamacher, A; Hansen, FK; Kassack, MU; Kuna, K; Kurz, T; Marek, L; Meister, S; Mordmüller, B; Schmetter, R; Stenzel, K; Sumanadasa, SD; Winzeler, EA1
Bathurst, I; Burrows, JN; Charman, SA; Cross, RM; Flanigan, DL; Fronczek, FR; Guida, WC; Kyle, DE; LaCrue, AN; Maignan, JR; Manetsch, R; Monastyrskyi, A; Mutka, TS; Sáenz, FE; Shackleford, DM; White, KL; Wojtas, L1
Avery, VM; Barth, S; Duffy, S; Frank, W; Geffken, D; Held, J; Kamber, J; Kuna, K; Kurz, T; Leven, M; Mordmüller, B; Sax, S; Siethoff, C; Tschan, S; Wittlin, S1
Cabrera, DG; Cheuka, PM; Chibale, K; Paquet, T1
Birkholtz, LM; N'Da, DD; Smit, FJ; van Biljon, RA1
Akoto, M; Avery, VM; Duffy, S; Hagen, TJ; Helgren, TR; Igbinoba, O; Lee, P; Sciotti, RJ1
Chibale, K; D'hooghe, M; Danneels, B; de Kock, C; Desmet, T; Smith, PJ; Van Herreweghe, S; Vandekerckhove, S; Willems, J1
Bacher, A; Behrendt, C; Brücher, K; Fischer, M; Gräwert, T; Held, J; Illarionov, B; Konzuch, S; Kurz, T; Lienau, C; Maes, L; Mordmüller, B; Wittlin, S1
Aroonkit, P; Krajangsri, S; Mungthin, M; Ruchirawat, S; Thongsornkleeb, C; Tummatorn, J1
Azas, N; Basmaciyan, L; Cohen, A; Crozet, MD; Dallemagne, P; Deharo, E; Dumètre, A; Hutter, S; Laget, M; Lancelot, JC; Lesnard, A; Lorthiois, A; Mazier, D; Paloque, L; Rathelot, P; Rault, S; Sibley, CH; Suzanne, P; Valentin, A; Vanelle, P; Verhaeghe, P1
Abramo, C; Carlos, BC; da Fonseca, CC; da Silva, AD; da Silva, JM; de Paula Dias, RM; de Pila Varotti, F; de Souza, LS; Lopes, FV; Moreira, PO; Scopel, KK; Soares, RR; Viana, GH1
Balzarini, J; Chibale, K; de Kock, C; Kaur, H; Singh, K; Smith, PJ1
Chibale, K; de Kock, C; Kaur, H; Machado, M; Prudêncio, M; Singh, K; Smith, P1
Blackie, MAL; de Kock, C; Pelly, SC; Smith, PJ; Taleli, L; van Otterlo, WAL1
Efferth, T; Friedrich, O; Fröhlich, T; Gruber, L; Hutterer, C; Kappes, B; Marschall, M; Reiter, C; Tsogoeva, SB; Voigtländer, C1
Coelho, L; Lukens, AK; Mazitschek, R; Moreira, R; Nogueira, F; Paulo, A; Santos, SA; Wirth, DF1
Chibale, K; Douelle, F; Gonzàlez Cabrera, D; Han, Z; Lawrence, N; Le Manach, C; Njoroge, M; Paquet, T; Street, LJ; Taylor, D; Waterson, D; Wiesner, L; Wittlin, S; Witty, MJ1
Angulo-Barturen, I; Bashyam, S; Birkholtz, LM; Botha, M; Brunschwig, C; Chibale, K; Churchyard, A; Coetzer, TL; Dhinakaran, R; Ferrer, S; Gonzàlez Cabrera, D; Han, Z; Jiménez-Díaz, MB; Lauterbach, S; Le Manach, C; Meister, S; Njoroge, M; Paquet, T; Reader, J; Santos Martínez, M; Street, LJ; Taylor, D; Waterson, D; Winzeler, EA; Wittlin, S; Witty, MJ1
Avery, V; Derese, S; Deyou, T; Duffy, S; Erdélyi, M; Fitzpatrick, PA; Gruhonjic, A; Gumula, I; Heydenreich, M; Holleran, J; Landberg, G; Mumo, M; Pang, F; Rissanen, K; Yenesew, A1
Beteck, RM; Birkholtz, LM; Coertzen, D; Haynes, RK; N'Da, DD; Smit, FJ1
Combrinck, J; de Kock, C; N'Da, DD; Smit, FJ; Smith, PJ; Zuma, NH1
Angulo-Barturen, I; Antonova-Koch, Y; Bashyam, S; Birkholtz, LM; Botha, ME; Charman, SA; Chibale, K; Ferrer, S; Gonzàlez Cabrera, D; Han, Z; Jiménez-Díaz, MB; Lawrence, N; Le Manach, C; Martínez, MS; Meister, S; Nchinda, AT; Nondaba, SH; Paquet, T; Reader, J; Street, LJ; Taylor, D; Waterson, D; White, KL; Winzeler, EA; Wittlin, S; Witty, MJ; Younis, Y; Zabiulla, M1
Chibale, K; De Kock, C; Espinoza-Moraga, M; Kaur, G; Njoroge, M; Okombo, J; Singh, K; Smith, PJ; Wittlin, S1
Dong, G; Liu, N; Sheng, C; Wang, Y; Wu, S1
Avery, VM; Baell, JB; Bullen, HE; Cowman, AF; Crabb, BS; Curtis, JM; Di Rago, AE; Duffy, S; Gilson, PR; Hutton, CA; Jarman, KE; Jousset Subroux, H; Lowes, KN; Nguyen, W; Prinz, B; Sleebs, BE; Tan, C1
Avery, VM; Carroll, AR; Duffy, S; Senadeera, SPD1
Avery, VM; Buchholz, M; Delves, MJ; Duffy, S; Fischli, C; Held, J; Knaab, TC; Kuna, K; Kurz, T; Lehmann, U; Leven, M; Lungerich, B; Meister, S; Meitzner, D; Mordmüller, B; Stahlke, P; Winzeler, EA; Wittlin, S1
Avery, VM; Davis, RA; Duffy, S; Kumar, R1
Copp, BR; Kaiser, M; Pearce, AN1
Chibale, K; Egan, TJ; Hunter, R; Joshi, MC; Ndove, J; Nsumiwa, S; Okombo, J; Taylor, D; Wiesner, L1
Avery, VM; Carroll, AR; Duffy, S; Robertson, LP; Wang, D; Wang, Y1
Aguiar, ACC; Berlinck, RGS; Bertonha, AF; Costa, TR; de Souza, GE; Ferreira, AG; Gadelha, FR; Grazzia, N; Guido, RVC; Hajdu, E; Miguel, DC; Oliva, G; Parra, LLL; Romo, D; Severo, IRM1
Bonnet, SL; Noreljaleel, AEM; van der Westhuizen, JH; Wilhelm, A1
Chibale, K; Chopra, R; Singh, K1
Avery, VM; Carroll, AR; Davis, RA; Duffy, S; Kumar, R1
Abay, E; Angulo-Barturen, I; Brunschwig, C; Burrows, J; Chibale, K; Duffy, J; Ferrer, S; Gonzàlez Cabrera, D; Jiménez-Díaz, MB; Lafuente-Monasterio, MJ; Lawrence, N; Le Manach, C; Nchinda, AT; Njoroge, M; Paquet, T; Santos Martínez, M; Street, LJ; Taylor, D; Wicht, KJ; Wittlin, S1
Aguiar, ACC; Correia, CRD; Costa, JL; de Souza, GE; Garcia, CRS; Garcia, ML; Guido, RVC; Nakabashi, M; Oliva, G; Panciera, M; Simão Dos Santos, EF; Singh, MK1
Çapcı Karagöz, A; Efferth, T; Friedrich, O; Gruber, L; Hahn, F; Hampel, F; Kappes, B; Klein, V; Leidenberger, M; Marschall, M; Reiter, C; Seo, EJ; Tsogoeva, SB1
Avery, VM; Carroll, AR; Duffy, S; Lucantoni, L; Senadeera, SPD1
Chibale, K; Kaur, G; Pavadai, E; Wittlin, S1
Andrews, KT; Antonova-Koch, Y; Avery, VM; Diedrich, D; Duffy, S; Fisher, G; Gebru, T; Hansen, FK; Held, J; Hesping, E; Kurz, T; Meister, S; Schöler, A; Stenzel, K; Winzeler, EA1
Basarab, GS; Brunschwig, C; Chibale, K; Duffy, J; Eyermann, CJ; Fish, PV; Gibhard, L; Lawrence, N; Le Manach, C; Nchinda, AT; Njoroge, M; Paquet, T; Street, LJ; Taylor, D; Wicht, K; Wittlin, S1
Higuchi, T; Hisamatsu, Y; Ishikawa, H; Kato, K; Kato, N; Kim, HS; Kobayashi, Y; Omiya, H; Sakata, Y; Satoh, T; Tomita, Y; Umezawa, N; Wataya, Y; Yabunaka, K; Yagi, H1
Blackie, MAL; de Kock, C; Jacobs, L; Pelly, SC; Taylor, D1
Cheuka, PM; Chibale, K; Lawrence, N; Taylor, D; Wittlin, S1
Avery, VM; Butler, GS; Drinkwater, N; Duffy, S; Grin, PM; Kassiou, M; Lucantoni, L; Malcolm, TR; McGowan, S; Overall, CM; Scammells, PJ; Vinh, NB1
Bezuidenhout, B; Birkholtz, LM; Chibale, K; Churchyard, A; Coetzer, TL; Egan, TJ; Fontinha, D; Gibhard, L; Lauterbach, S; Mayoka, G; Njoroge, M; Okombo, J; Prudêncio, M; Reader, J; Sanches-Vaz, M; van der Watt, M; Wittlin, S; Yeates, C1
Aguiar, ACC; de Souza, JO; Fagundez, C; Gamo, FJ; Guido, RVC; Ottilie, S; Peña, S; Sanz, LM; Scarone, L; Sellanes, D; Serra, GL; Stewart, L; Winzeler, EA; Yardley, V1
Avery, VM; Baell, JB; Ban, K; Beveridge, JG; Blundell, S; Charman, SA; Chavchich, M; Chiu, FCK; Creek, D; Cuellar, ME; Dahlin, JL; Diab, S; Dingjan, T; Duffy, S; Edstein, MD; Ellis, K; Fletcher, S; Harjani, JR; Huang, F; Lucantoni, L; Marfurt, J; Noviyanti, R; Price, RN; Ralph, SA; Shi, DH; Strasser, JM; Teguh, S; Walters, MA; Wirjanata, G; Xue, L1
Avery, VM; Carroll, AR; Duffy, S; Lucantoni, L; Robertson, LP1
Das, D; Hong, J1
Attram, HD; Chibale, K; Wittlin, S1
Das, US; Khan, SI; Ponnan, P; Rawat, DS; Taylor, D; Tekwani, BL; Tripathi, M; Velpandian, T1
Berger, O; Bressolle, F; Denoyelle, S; Durand, T; Escale, R; Ortial, S; Vial, HJ; Vo-Hoang, Y; Wein, S1
Baartzes, N; Chibale, K; Seldon, R; Smith, GS; Stringer, T; Taylor, D; Warner, DF; Wittlin, S1
Banchio, C; Bofill Verdaguer, I; Ferreira de Azevedo, M; Katzin, AM; Labadie, GR; Perez, C; Porta, EOJ1
Cheong, SL; Ng, CH; Tibon, NS1
Avery, VM; Carroll, AR; Duffy, S; Kleks, G; Lucantoni, L1
Avery, VM; Duffy, S; Erdélyi, M; Lindblad, S; Maeda, G; Munissi, JJE; Nyandoro, SS; Pelletier, J1
Bourchenin, G; Cerdan, R; Cheviet, T; Lagacherie, M; Périgaud, C; Peyrottes, S; Wein, S1
Atilaw, Y; Avery, VM; Bogaerts, J; Duffy, S; Erdélyi, M; Heydenreich, M; Muiva-Mutisya, L; Rissanen, K; Valkonen, A; Yenesew, A1
Aguiar, ACC; Albuquerque, MG; Boechat, N; Campos, VR; de Souza, JO; Guido, RVC; Hoelz, LVB; Jabor, VAP; Nonato, MC; Pinheiro, LCS; Silveira, FF1
Beteck, RM; Legoabe, LJ; Patel, OPS1
Avery, VM; Dans, MG; de Koning-Ward, TF; Duffy, S; Gancheva, MR; Gilson, PR; Lowes, KN; Ngo, A; Nguyen, W; Romeo, O; Sabroux, HJ; Sleebs, BE; Wilson, DW1
Baum, J; Bridgford, JL; Charman, SA; Churchyard, A; Crespo, B; Deni, I; Fidock, DA; Gahalawat, S; Gamo, FJ; Laleu, B; Lawong, A; Mittal, N; Mok, S; Niederstrasser, H; Okombo, J; Palmer, MJ; Phillips, MA; Posner, B; Ready, JM; Striepen, J; Winzeler, E; Wittlin, S; Yeo, T; Zhou, A1
Avery, VM; Challis, MP; Creek, DJ; De Paoli, A; Devine, SM; Kigotho, JK; MacRaild, CA; Norton, RS; Scammells, PJ; Siddiqui, G1
Akao, Y; Avery, VM; Charman, SA; Chen, G; Chen, X; Chiu, FCK; Cho, N; Crespo, B; Dechering, KJ; Duffy, S; Kamaura, M; Katneni, K; Laleu, B; Lucantoni, L; Ochida, A; Sanz, LM; Shackleford, DM; Sturm, A; Wang, B; White, KL; Wittlin, S1

Reviews

6 review(s) available for chloroquine and artesunate

ArticleYear
Recent advances in malaria drug discovery.
    Bioorganic & medicinal chemistry letters, 2013, May-15, Volume: 23, Issue:10

    Topics: Animals; Antimalarials; Drug Discovery; Humans; Liver; Liver Transplantation; Malaria; Molecular Structure

2013
Approaches to protozoan drug discovery: phenotypic screening.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi

2013
Tackling Fungal Resistance by Biofilm Inhibitors.
    Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6

    Topics: Animals; Antifungal Agents; Biofilms; Drug Discovery; Drug Resistance, Fungal; Fungi; Humans; Models, Molecular; Mycoses; Small Molecule Libraries

2017
Recent advancements of 4-aminoquinazoline derivatives as kinase inhibitors and their applications in medicinal chemistry.
    European journal of medicinal chemistry, 2019, May-15, Volume: 170

    Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Neoplasms; Protein Kinase Inhibitors; Quinazolines

2019
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
    European journal of medicinal chemistry, 2020, Feb-15, Volume: 188

    Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines

2020
Antimalarial application of quinones: A recent update.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Antimalarials; Dose-Response Relationship, Drug; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinones; Structure-Activity Relationship

2021

Other Studies

105 other study(ies) available for chloroquine and artesunate

ArticleYear
Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid.
    Journal of medicinal chemistry, 2002, Oct-24, Volume: 45, Issue:22

    Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Heterocyclic Compounds, 3-Ring; Hydrolysis; Malaria; Mice; Plasmodium; Solubility; Stereoisomerism

2002
Antimalarial activities of (+)-deoxoartemisitene and its novel C-11, 13 derivatives.
    Bioorganic & medicinal chemistry letters, 2004, Apr-19, Volume: 14, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Drug Evaluation, Preclinical; Molecular Structure; Plasmodium falciparum

2004
Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.
    Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15

    Topics: Adamantane; Animals; Antimalarials; Cell Line, Tumor; Drug Resistance; Half-Life; Malaria; Malaria, Falciparum; Mice; Micronucleus Tests; Ozone; Peroxides; Plasmodium berghei; Rats; Spiro Compounds; Structure-Activity Relationship

2005
Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytes.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Aminoquinolines; Animals; Antimalarials; Erythrocytes; Mice; Plasmodium falciparum

2007
Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10

    Topics: Alkylation; Animals; Antimalarials; Artemisinins; Chloroquine; Dioxanes; Heme; Hemeproteins; Plasmodium; Sesquiterpenes; Spectrophotometry, Infrared

2007
Determinants of in vitro drug susceptibility testing of Plasmodium vivax.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3

    Topics: Animals; Antimalarials; Chloroquine; Humans; Inhibitory Concentration 50; Life Cycle Stages; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax; Schizonts; Time Factors

2008
Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum.
    Journal of medicinal chemistry, 2008, Mar-13, Volume: 51, Issue:5

    Topics: Animals; Antimalarials; Biological Transport; Cell Line, Tumor; Chloroquine; Drug Resistance; Drug Therapy, Combination; Glutathione Reductase; Humans; In Vitro Techniques; Malaria; Mice; Mice, Inbred BALB C; Naphthalenes; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Stronger activity of human immunodeficiency virus type 1 protease inhibitors against clinical isolates of Plasmodium vivax than against those of P. falciparum.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Animals; Antimalarials; Drug Resistance, Multiple; Gene Dosage; Genes, MDR; Genes, Protozoan; HIV Infections; HIV Protease Inhibitors; Humans; In Vitro Techniques; Malaria, Falciparum; Malaria, Vivax; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax; Ritonavir; Saquinavir

2008
In vivo and in vitro efficacy of amodiaquine monotherapy for treatment of infection by chloroquine-resistant Plasmodium vivax.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Adolescent; Age Distribution; Amodiaquine; Animals; Antimalarials; Chloroquine; Confidence Intervals; Drug Resistance; Drug Tolerance; Female; Follow-Up Studies; Humans; Inhibitory Concentration 50; Male; Outpatients; Parasitemia; Plasmodium vivax; Prospective Studies; Recurrence; Rural Health; Time Factors; Treatment Failure; Treatment Outcome

2009
Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Erythrocytes; Humans; Interleukin Receptor Common gamma Subunit; Kinetics; Malaria, Falciparum; Mice; Mice, Inbred NOD; Mice, SCID; Pyridones; Pyrimethamine

2009
A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:12

    Topics: Amodiaquine; Animals; Anthelmintics; Antiprotozoal Agents; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Leishmania donovani; Macrophages; Mice; Molecular Structure; Plasmodium falciparum

2009
Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.
    Journal of medicinal chemistry, 2009, Dec-24, Volume: 52, Issue:24

    Topics: Aminoquinolines; Antimalarials; Ciprofloxacin; Ferrous Compounds; Metallocenes; Plasmodium falciparum; Prodrugs

2009
The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).
    Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1

    Topics: Animals; Antimalarials; Heterocyclic Compounds, 1-Ring; Malaria, Falciparum; Mice; Molecular Conformation; Parasitic Sensitivity Tests; Peroxides; Plasmodium falciparum; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship

2010
The comparative antimalarial properties of weak base and neutral synthetic ozonides.
    Bioorganic & medicinal chemistry letters, 2010, Jan-15, Volume: 20, Issue:2

    Topics: Animals; Antimalarials; Heterocyclic Compounds; Mice; Plasmodium falciparum; Rats

2010
Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Drug Resistance, Bacterial; Erythrocytes; Flow Cytometry; Gene Expression Profiling; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Oligonucleotide Array Sequence Analysis; Parasitic Sensitivity Tests; Plasmodium falciparum; Thailand

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Drug Resistance; Female; Folic Acid Antagonists; Humans; In Vitro Techniques; Malaria; Malaria, Falciparum; Male; Mice; Models, Molecular; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinazolines; Rats; Rats, Wistar; Tetrahydrofolate Dehydrogenase

2010
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Animals; Antimalarials; Drug Resistance, Multiple; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum

2010
Spirotetrahydro beta-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Animals; Antimalarials; Carbolines; Cell Line; Crystallography, X-Ray; Humans; In Vitro Techniques; Indoles; Malaria; Mice; Microsomes, Liver; Molecular Structure; Plasmodium berghei; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship

2010
Spiroindolones, a potent compound class for the treatment of malaria.
    Science (New York, N.Y.), 2010, Sep-03, Volume: 329, Issue:5996

    Topics: Adenosine Triphosphatases; Animals; Antimalarials; Cell Line; Drug Discovery; Drug Resistance; Erythrocytes; Female; Genes, Protozoan; Humans; Indoles; Malaria; Male; Mice; Models, Molecular; Mutant Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Plasmodium vivax; Protein Synthesis Inhibitors; Protozoan Proteins; Rats; Rats, Wistar; Spiro Compounds

2010
In vitro activity of pyronaridine against multidrug-resistant Plasmodium falciparum and Plasmodium vivax.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Inhibitory Concentration 50; Naphthyridines; Plasmodium falciparum; Plasmodium vivax

2010
In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Female; Humans; Indonesia; Malaria; Male; Middle Aged; Plasmodium malariae; Plasmodium ovale; Treatment Outcome; Young Adult

2011
Ex vivo activity of histone deacetylase inhibitors against multidrug-resistant clinical isolates of Plasmodium falciparum and P. vivax.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:3

    Topics: Drug Resistance, Multiple, Bacterial; Histone Deacetylase Inhibitors; Hydroxamic Acids; Microbial Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax; Vorinostat

2011
Phenolic glycosides with antimalarial activity from Grevillea "Poorinda Queen".
    Journal of natural products, 2011, Jan-28, Volume: 74, Issue:1

    Topics: Animals; Antimalarials; Australia; Chloroquine; Drug Resistance; Drug Screening Assays, Antitumor; Glycosides; HEK293 Cells; Hep G2 Cells; Humans; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenols; Plant Leaves; Plant Stems; Plasmodium falciparum; Proteaceae

2011
Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice.
    Journal of medicinal chemistry, 2011, Jun-09, Volume: 54, Issue:11

    Topics: Animals; Antimalarials; Dihydroorotate Dehydrogenase; Disease Models, Animal; Drug Design; Drug Discovery; Enzyme Inhibitors; Humans; Malaria; Mice; Microsomes, Liver; Molecular Structure; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium berghei; Plasmodium falciparum; Protein Binding; Pyrimidines; Solubility; Structure-Activity Relationship; Triazoles

2011
Imidazolopiperazines: hit to lead optimization of new antimalarial agents.
    Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14

    Topics: Amino Acids; Aniline Compounds; Animals; Antimalarials; Benzene Derivatives; Cell Line; Drug Resistance; Female; Humans; Imidazoles; Inhibitory Concentration 50; Malaria; Mice; Mice, Inbred BALB C; Piperazines; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship

2011
3-Alkoxy-1,2-Dioxolanes: Synthesis and Evaluation as Potential Antimalarial Agents.
    ACS medicinal chemistry letters, 2011, Apr-14, Volume: 2, Issue:4

    Topics:

2011
Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential.
    Journal of medicinal chemistry, 2011, Aug-11, Volume: 54, Issue:15

    Topics: Animals; Antimalarials; Chemical Phenomena; Crystallography, X-Ray; Dihydroorotate Dehydrogenase; Drug Resistance; Humans; Mice; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium falciparum; Pyrimidines; Rats; Structure-Activity Relationship; Triazoles

2011
Novel orally active antimalarial thiazoles.
    Journal of medicinal chemistry, 2011, Nov-10, Volume: 54, Issue:21

    Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Cytochrome P-450 CYP1A2 Inhibitors; Drug Interactions; Drug Resistance; Ether-A-Go-Go Potassium Channels; Humans; In Vitro Techniques; Injections, Intravenous; Malaria; Male; Mice; Microsomes; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles

2011
Febrifugine analogue compounds: synthesis and antimalarial evaluation.
    Bioorganic & medicinal chemistry, 2012, Jan-15, Volume: 20, Issue:2

    Topics: Animals; Antimalarials; Aotus trivirgatus; Drug Evaluation, Preclinical; Malaria; Piperidines; Plasmodium falciparum; Quinazolines

2012
2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.
    European journal of medicinal chemistry, 2012, Volume: 52

    Topics: Aminoquinolines; Animals; Antimalarials; Cell Line; DNA; Dogs; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Plasmodium falciparum; Protoporphyrins; Pyrimidines; Structure-Activity Relationship; Viruses

2012
Imidazolopiperazines: lead optimization of the second-generation antimalarial agents.
    Journal of medicinal chemistry, 2012, May-10, Volume: 55, Issue:9

    Topics: Animals; Antimalarials; Biological Availability; Caco-2 Cells; Humans; Imidazoles; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Piperazines; Plasmodium falciparum; Rats; Rats, Wistar; Structure-Activity Relationship

2012
Antiproliferative and antiplasmodial dimeric phloroglucinols from Mallotus oppositifolius from the Madagascar Dry Forest (1).
    Journal of natural products, 2013, Mar-22, Volume: 76, Issue:3

    Topics: Antimalarials; Antineoplastic Agents, Phytogenic; Chloroquine; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Madagascar; Mallotus Plant; Molecular Structure; Phloroglucinol; Plant Leaves; Plasmodium falciparum; Trees

2013
Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277, OZ439, and their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres.
    Journal of medicinal chemistry, 2013, Mar-28, Volume: 56, Issue:6

    Topics: Absorption; Adamantane; Animals; Antimalarials; Dioxolanes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Male; Mice; Peroxides; Plasmodium berghei; Plasmodium falciparum; Spiro Compounds; Structure-Activity Relationship; Tetraoxanes

2013
Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies.
    European journal of medicinal chemistry, 2013, Volume: 66

    Topics: Antimalarials; Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; DNA; Heme; Humans; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship

2013
Antimalarial and cytotoxic activities of chiral triamines.
    Bioorganic & medicinal chemistry letters, 2013, Aug-15, Volume: 23, Issue:16

    Topics: Animals; Antimalarials; Artemisinins; Cell Line; Cell Survival; Chloroquine; Cyclization; Humans; Plasmodium falciparum; Polyamines; Small Molecule Libraries

2013
Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity.
    Journal of medicinal chemistry, 2013, Aug-08, Volume: 56, Issue:15

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Drug Resistance; HEK293 Cells; Hemeproteins; Hemoglobins; Humans; Indoles; Inhibitory Concentration 50; Membrane Potential, Mitochondrial; Mitochondria; Plasmodium falciparum; Structure-Activity Relationship

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
    Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23

    Topics: Antimalarials; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Dimerization; Humans; Malaria, Falciparum; Neoplasms; Plasmodium falciparum; Tetraoxanes

2013
Synthesis of halogenated 4-quinolones and evaluation of their antiplasmodial activity.
    Bioorganic & medicinal chemistry letters, 2014, Feb-15, Volume: 24, Issue:4

    Topics: 4-Quinolones; Animals; Antimalarials; Cell Survival; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2014
Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1.
    Journal of medicinal chemistry, 2014, Mar-27, Volume: 57, Issue:6

    Topics: Animals; Antimalarials; Biological Availability; Drug Design; Drug Resistance; Drug Stability; Gene Library; Half-Life; High-Throughput Screening Assays; Imidazoles; Malaria; Malaria, Falciparum; Mice; Mice, SCID; Parasitic Sensitivity Tests; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Protein Kinase Inhibitors; Protein Kinases; Pyridazines; Rats; Structure-Activity Relationship

2014
Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Antimalarials; Dose-Response Relationship, Drug; Drug Discovery; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Repressor Proteins; Structure-Activity Relationship

2014
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Animals; Antimalarials; Humans; Inhibitory Concentration 50; Malaria; Mice; Microsomes, Liver; Parasitemia; Plasmodium; Plasmodium berghei; Quinolones; Structure-Activity Relationship

2014
Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds.
    Journal of medicinal chemistry, 2014, Oct-09, Volume: 57, Issue:19

    Topics: Animals; Antimalarials; Chloroquine; Malaria; Mice; Parasitemia; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship

2014
Structure-activity relationship studies of antiplasmodial aminomethylthiazoles.
    Bioorganic & medicinal chemistry letters, 2014, Nov-15, Volume: 24, Issue:22

    Topics: Animals; Antimalarials; Mice; Plasmodium falciparum; Structure-Activity Relationship; Thiazoles

2014
Synthesis and in vitro biological evaluation of dihydroartemisinyl-chalcone esters.
    European journal of medicinal chemistry, 2015, Jan-27, Volume: 90

    Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; Humans; MCF-7 Cells; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2015
The synthesis, antimalarial activity and CoMFA analysis of novel aminoalkylated quercetin analogs.
    Bioorganic & medicinal chemistry letters, 2015, Jan-15, Volume: 25, Issue:2

    Topics: Antimalarials; Humans; Malaria; Models, Molecular; Molecular Structure; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Quercetin; Stereoisomerism

2015
Synthesis of functionalized 3-, 5-, 6- and 8-aminoquinolines via intermediate (3-pyrrolin-1-yl)- and (2-oxopyrrolidin-1-yl)quinolines and evaluation of their antiplasmodial and antifungal activity.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Aminoquinolines; Antifungal Agents; Antimalarials; Aspergillus flavus; Dose-Response Relationship, Drug; Parasitic Sensitivity Tests; Plasmodium falciparum; Rhodotorula; Structure-Activity Relationship

2015
Prodrugs of reverse fosmidomycin analogues.
    Journal of medicinal chemistry, 2015, Feb-26, Volume: 58, Issue:4

    Topics: Animals; Antimalarials; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Fosfomycin; HeLa Cells; Humans; Malaria; Mice; Mice, SCID; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship

2015
Synthesis of isocryptolepine analogues and their structure-activity relationship studies as antiplasmodial and antiproliferative agents.
    European journal of medicinal chemistry, 2015, Apr-13, Volume: 94

    Topics: Antimalarials; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Chemistry Techniques, Synthetic; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Indole Alkaloids; Plasmodium falciparum; Quinolines; Structure-Activity Relationship

2015
Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium.
    European journal of medicinal chemistry, 2015, May-05, Volume: 95

    Topics: Animals; Antimalarials; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Drug Discovery; Erythrocytes; Hep G2 Cells; Humans; Liver; Malaria; Male; Mice; Parasitemia; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship; Trophozoites

2015
New quinoline derivatives demonstrate a promising antimalarial activity against Plasmodium falciparum in vitro and Plasmodium berghei in vivo.
    Bioorganic & medicinal chemistry letters, 2015, Jun-01, Volume: 25, Issue:11

    Topics: Animals; Antimalarials; Malaria; Mice; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Quinolines

2015
Synthesis, antiplasmodial activity and mechanistic studies of pyrimidine-5-carbonitrile and quinoline hybrids.
    European journal of medicinal chemistry, 2015, Aug-28, Volume: 101

    Topics: Animals; Antimalarials; Antiviral Agents; Cell Line; DNA Viruses; Dose-Response Relationship, Drug; Heme; Humans; Mice; Models, Molecular; Molecular Structure; Nitriles; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimidines; Quinolines; RNA Viruses; Structure-Activity Relationship

2015
Primaquine-pyrimidine hybrids: synthesis and dual-stage antiplasmodial activity.
    European journal of medicinal chemistry, 2015, Aug-28, Volume: 101

    Topics: Animals; Antimalarials; Cell Line; Dose-Response Relationship, Drug; Humans; Liver; Mice; Mice, Inbred C57BL; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Primaquine; Pyrimidines; Structure-Activity Relationship

2015
In vitro antiplasmodial activity of triazole-linked chloroquinoline derivatives synthesized from 7-chloro-N-(prop-2-yn-1-yl)quinolin-4-amine.
    Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15

    Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Click Chemistry; Drug Evaluation, Preclinical; Drug Resistance; Molecular Structure; Plasmodium falciparum; Triazoles

2015
Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities.
    Bioorganic & medicinal chemistry, 2015, Sep-01, Volume: 23, Issue:17

    Topics: Antimalarials; Antineoplastic Agents, Phytogenic; Antiviral Agents; Artemisinins; Humans; Molecular Structure

2015
Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype.
    European journal of medicinal chemistry, 2015, Sep-18, Volume: 102

    Topics: Antimalarials; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Indoles; Malaria; Molecular Structure; Niacinamide; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2015
Structure-Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidines.
    Journal of medicinal chemistry, 2015, Sep-24, Volume: 58, Issue:18

    Topics: Administration, Oral; Animals; Antimalarials; Crystallography, X-Ray; Drug Resistance; Ether-A-Go-Go Potassium Channels; Female; Humans; Malaria; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Patch-Clamp Techniques; Plasmodium berghei; Plasmodium falciparum; Protein Conformation; Pyrimidines; Solubility; Structure-Activity Relationship

2015
A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.
    Journal of medicinal chemistry, 2015, Nov-12, Volume: 58, Issue:21

    Topics: Animals; Antimalarials; Ether-A-Go-Go Potassium Channels; Humans; Liver; Malaria; Malaria, Falciparum; Mice; Plasmodium berghei; Plasmodium falciparum; Pyrazoles; Pyridines; Rats; Structure-Activity Relationship

2015
Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis.
    Journal of natural products, 2015, Dec-24, Volume: 78, Issue:12

    Topics: Antimalarials; Chalcones; Chloroquine; Crystallography, X-Ray; Flavanones; Flavonoids; HEK293 Cells; Humans; Millettia; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plant Extracts; Plasmodium falciparum

2015
Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities.
    Bioorganic & medicinal chemistry letters, 2016, 07-01, Volume: 26, Issue:13

    Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Decoquinate; Drug Resistance, Multiple; Emetine; Humans; Inhibitory Concentration 50; Plasmodium falciparum; Quinolones

2016
Synthesis and biological evaluation of a series of non-hemiacetal ester derivatives of artemisinin.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Artemisinins; Cell Line, Tumor; Chemistry Techniques, Synthetic; CHO Cells; Cricetinae; Cricetulus; Drug Design; Esters; Humans; Plasmodium falciparum

2016
Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle.
    Journal of medicinal chemistry, 2016, 11-10, Volume: 59, Issue:21

    Topics: Animals; Antimalarials; Disease Models, Animal; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Hep G2 Cells; Humans; Life Cycle Stages; Malaria; Mice; Mice, SCID; Microsomes, Liver; Molecular Structure; Parasitic Diseases, Animal; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyrazines; Solubility; Structure-Activity Relationship; Water

2016
Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: Amides; Antimalarials; Chloroquine; Drug Resistance; Esters; Fusidic Acid; Plasmodium falciparum; Structure-Activity Relationship

2017
Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity.
    Journal of medicinal chemistry, 2017, 02-09, Volume: 60, Issue:3

    Topics: Administration, Oral; Animals; Antimalarials; Disease Models, Animal; Mice; Plasmodium falciparum; Quinazolines; Structure-Activity Relationship

2017
Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana.
    Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11

    Topics: Antimalarials; Australia; Cell Survival; Chloroquine; Drug Resistance; Flowers; HEK293 Cells; Humans; Ketones; Magnetic Resonance Spectroscopy; Molecular Conformation; Myrtaceae; Plant Extracts; Plasmodium falciparum; Sesquiterpenes

2017
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.
    Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14

    Topics: Amides; Animals; Antimalarials; Hep G2 Cells; Humans; Hydrazones; Malaria; Mice; Phenanthrenes; Plasmodium berghei; Stereoisomerism; Structure-Activity Relationship

2017
Synthesis of antimalarial amide analogues based on the plant serrulatane diterpenoid 3,7,8-trihydroxyserrulat-14-en-19-oic acid.
    Bioorganic & medicinal chemistry letters, 2017, 09-01, Volume: 27, Issue:17

    Topics: Amides; Antimalarials; Australia; Biological Products; Cell Survival; Diterpenes; Dose-Response Relationship, Drug; Eremophila Plant; HEK293 Cells; Humans; Molecular Structure; Plant Extracts; Plasmodium falciparum; Structure-Activity Relationship

2017
Synthesis and antimalarial evaluation of artesunate-polyamine and trioxolane-polyamine conjugates.
    European journal of medicinal chemistry, 2017, Nov-10, Volume: 140

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Humans; Polyamines; Rats; Spectrum Analysis; Structure-Activity Relationship

2017
4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice.
    Journal of medicinal chemistry, 2017, 12-28, Volume: 60, Issue:24

    Topics: Administration, Oral; Aminopyridines; Aminoquinolines; Animals; Antimalarials; Cell Membrane Permeability; Chloroquine; CHO Cells; Cricetulus; Drug Evaluation, Preclinical; Drug Resistance, Microbial; ERG1 Potassium Channel; Hemeproteins; Humans; Malaria; Male; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Solubility; Structure-Activity Relationship

2017
Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana.
    Journal of natural products, 2017, 12-22, Volume: 80, Issue:12

    Topics: Antimalarials; Australia; Biological Products; Indole Alkaloids; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves; Plasmodium falciparum; Rutaceae; Trees

2017
Isolation, Derivative Synthesis, and Structure-Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis.
    Journal of natural products, 2018, 01-26, Volume: 81, Issue:1

    Topics: Alkaloids; Animals; Antimalarials; Antiparasitic Agents; Antiprotozoal Agents; Chagas Disease; Leishmania infantum; Leishmaniasis, Visceral; Parasitic Sensitivity Tests; Plasmodium falciparum; Porifera; Structure-Activity Relationship; Trypanosoma cruzi

2018
Synthesis and Bioactivity of Reduced Chalcones Containing Sulfonamide Side Chains.
    Journal of natural products, 2018, 01-26, Volume: 81, Issue:1

    Topics: Antimalarials; Chalcones; Inhibitory Concentration 50; Mycobacterium tuberculosis; Plasmodium falciparum; Structure-Activity Relationship; Sulfonamides

2018
Pyrimidine-chloroquinoline hybrids: Synthesis and antiplasmodial activity.
    European journal of medicinal chemistry, 2018, Mar-25, Volume: 148

    Topics: Animals; Antiprotozoal Agents; Binding Sites; Chlorocebus aethiops; Chloroquine; DNA; Drug Resistance; Hemin; Plasmodium falciparum; Pyrimidines; Vero Cells

2018
Microthecaline A, a Quinoline Serrulatane Alkaloid from the Roots of the Australian Desert Plant Eremophila microtheca.
    Journal of natural products, 2018, 04-27, Volume: 81, Issue:4

    Topics: Alkaloids; Antimalarials; Australia; Biological Products; Eremophila Plant; Plant Extracts; Plant Roots; Plasmodium falciparum; Quinolines

2018
Identification of Fast-Acting 2,6-Disubstituted Imidazopyridines That Are Efficacious in the in Vivo Humanized Plasmodium falciparum NODscidIL2Rγ
    Journal of medicinal chemistry, 2018, 05-10, Volume: 61, Issue:9

    Topics: Animals; Disease Models, Animal; Drug Discovery; Drug Stability; ERG1 Potassium Channel; Humans; Imidazoles; Malaria; Mice; Plasmodium falciparum; Pyridines; Solubility; Structure-Activity Relationship; Tissue Distribution; Water

2018
Discovery of Marinoquinolines as Potent and Fast-Acting Plasmodium falciparum Inhibitors with in Vivo Activity.
    Journal of medicinal chemistry, 2018, 07-12, Volume: 61, Issue:13

    Topics: Animals; Antimalarials; Drug Design; Mice; Models, Molecular; Molecular Conformation; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Quinolines

2018
Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin.
    Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

    Topics: Animals; Anisoles; Antimalarials; Antineoplastic Agents; Antiviral Agents; Artemisinins; Benzofurans; Benzoquinones; Biological Products; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Cytomegalovirus; Humans; Molecular Conformation; Plasmodium falciparum

2018
Antiplasmodial β-Triketone-Flavanone Hybrids from the Flowers of the Australian Tree Corymbia torelliana.
    Journal of natural products, 2018, 07-27, Volume: 81, Issue:7

    Topics: Antimalarials; Flavanones; Flowers; HEK293 Cells; Humans; Ketones; Magnetic Resonance Spectroscopy; Molecular Structure; Myrtaceae; Plant Extracts; Trees

2018
Identification of steroid-like natural products as antiplasmodial agents by 2D and 3D similarity-based virtual screening.
    MedChemComm, 2017, Jun-01, Volume: 8, Issue:6

    Topics:

2017
One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Acetylation; Antimalarials; Hep G2 Cells; Histone Deacetylase Inhibitors; Histones; Humans; Malaria, Falciparum; Peptoids; Plasmodium falciparum; Protozoan Proteins

2018
Antimalarial Lead-Optimization Studies on a 2,6-Imidazopyridine Series within a Constrained Chemical Space To Circumvent Atypical Dose-Response Curves against Multidrug Resistant Parasite Strains.
    Journal of medicinal chemistry, 2018, 10-25, Volume: 61, Issue:20

    Topics: Absorption, Physicochemical; Animals; Antimalarials; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Imidazoles; Mice; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Tissue Distribution

2018
Potent Antimalarial Activity of Two Arenes Linked with Triamine Designed To Have Multiple Interactions with Heme.
    ACS medicinal chemistry letters, 2018, Oct-11, Volume: 9, Issue:10

    Topics:

2018
Synthesis of five libraries of 6,5-fused heterocycles to establish the importance of the heterocyclic core for antiplasmodial activity.
    Bioorganic & medicinal chemistry, 2018, 11-15, Volume: 26, Issue:21

    Topics: Antimalarials; Benzimidazoles; Benzoxazoles; Indoles; Molecular Structure; Plasmodium falciparum; Small Molecule Libraries; Structure-Activity Relationship; Thiophenes

2018
Antiplasmodial imidazopyridazines: structure-activity relationship studies lead to the identification of analogues with improved solubility and hERG profiles.
    MedChemComm, 2018, Oct-01, Volume: 9, Issue:10

    Topics:

2018
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
    Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2

    Topics: Aminopeptidases; Antimalarials; Binding Sites; Catalytic Domain; Cell Survival; Drug Resistance; HEK293 Cells; Humans; Hydroxamic Acids; Molecular Docking Simulation; Plasmodium; Protease Inhibitors; Protozoan Proteins; Structure-Activity Relationship

2019
Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-trifluoromethyl Pyrido[1,2- a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria.
    Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2

    Topics: Animals; Antimalarials; Benzimidazoles; Disease Models, Animal; Drug Design; ERG1 Potassium Channel; Half-Life; Hemeproteins; Life Cycle Stages; Malaria; Mice; Mice, Inbred C57BL; Plasmodium; Structure-Activity Relationship; Survival Rate

2019
Synthesis, Profiling, and in Vivo Evaluation of Cyclopeptides Containing
    ACS medicinal chemistry letters, 2019, Jan-10, Volume: 10, Issue:1

    Topics:

2019
3,3'-Disubstituted 5,5'-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity.
    Journal of medicinal chemistry, 2019, 03-14, Volume: 62, Issue:5

    Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Plasmodium; Species Specificity; Structure-Activity Relationship; Triazines

2019
Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens.
    Journal of natural products, 2019, 04-26, Volume: 82, Issue:4

    Topics: Oxidation-Reduction; Plant Roots; Rutaceae; Xanthenes

2019
Incorporation of an intramolecular hydrogen bonding motif in the side chain of antimalarial benzimidazoles.
    MedChemComm, 2019, Mar-01, Volume: 10, Issue:3

    Topics:

2019
Hybridization of Fluoro-amodiaquine (FAQ) with Pyrimidines: Synthesis and Antimalarial Efficacy of FAQ-Pyrimidines.
    ACS medicinal chemistry letters, 2019, May-09, Volume: 10, Issue:5

    Topics:

2019
Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Antimalarials; Humans; Oximes; Plasmodium falciparum; Prodrugs

2019
Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids: Antimicrobial evaluation and mechanistic insights.
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Anti-Bacterial Agents; Antimalarials; Benzimidazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Ferrous Compounds; Malaria; Mice; Molecular Structure; Mycobacterium tuberculosis; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship

2019
Repositioning Salirasib as a new antimalarial agent.
    MedChemComm, 2019, Sep-01, Volume: 10, Issue:9

    Topics:

2019
Orthoscuticellines A-E, β-Carboline Alkaloids from the Bryozoan
    Journal of natural products, 2020, 02-28, Volume: 83, Issue:2

    Topics: Alkaloids; Animals; Australia; Bryozoa; Carbolines; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum

2020
A Meroisoprenoid, Heptenolides, and
    Journal of natural products, 2020, 02-28, Volume: 83, Issue:2

    Topics: Annonaceae; Antimalarials; Flavanones; Flavonoids; HEK293 Cells; Humans; Molecular Structure; Plant Extracts; Plant Leaves; Plasmodium berghei; Plasmodium falciparum

2020
β-Hydroxy- and β-Aminophosphonate Acyclonucleosides as Potent Inhibitors of
    Journal of medicinal chemistry, 2020, 08-13, Volume: 63, Issue:15

    Topics: Animals; Antimalarials; Female; Humans; K562 Cells; Malaria, Falciparum; Mice; Nucleosides; Organophosphonates; Plasmodium falciparum

2020
Prenylated Flavonoids from the Roots of
    Journal of natural products, 2020, 08-28, Volume: 83, Issue:8

    Topics: Antimalarials; Crystallography, X-Ray; Flavonoids; Molecular Structure; Plant Roots; Plasmodium falciparum; Prenylation; Spectrum Analysis; Tephrosia

2020
Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Antimalarials; Chloroquine; Dihydroorotate Dehydrogenase; Drug Design; Enzyme Inhibitors; Hep G2 Cells; Humans; Malaria, Falciparum; Molecular Docking Simulation; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium falciparum; Protein Binding; Pyrimidines; Quinolines; Structure-Activity Relationship; Triazoles

2021
Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion.
    European journal of medicinal chemistry, 2021, Mar-15, Volume: 214

    Topics: Animals; Antimalarials; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Erythrocytes; Hep G2 Cells; Humans; Malaria, Falciparum; Mice; Microsomes, Liver; Molecular Structure; Parasitic Sensitivity Tests; Piperazines; Plasmodium falciparum; Plasmodium knowlesi; Solubility; Structure-Activity Relationship

2021
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in
    Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5

    Topics: Amides; Antimalarials; Drug Resistance, Microbial; Hemeproteins; Hemoglobins; Hep G2 Cells; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Small Molecule Libraries; Structure-Activity Relationship; Tetrazoles

2021
Discovery and development of 2-aminobenzimidazoles as potent antimalarials.
    European journal of medicinal chemistry, 2021, Oct-05, Volume: 221

    Topics: Antimalarials; Benzimidazoles; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2021
Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials.
    Journal of medicinal chemistry, 2021, 09-09, Volume: 64, Issue:17

    Topics: Administration, Oral; Animals; Antimalarials; Humans; Malaria, Falciparum; Mice; Molecular Structure; Plasmodium falciparum; Quinazolinones; Structure-Activity Relationship

2021